Matthias W Laschke

Matthias W Laschke

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Matthias W Laschke

Matthias W Laschke

Publications by authors named "Matthias W Laschke"

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100Publications

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Vascularization, Regeneration and Tissue Engineering.

Authors:
Matthias W Laschke Brigitte Vollmar

Eur Surg Res 2018;59(3-4):230-231. Epub 2018 Sep 21.

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https://www.karger.com/Article/FullText/492372
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http://dx.doi.org/10.1159/000492372DOI Listing
September 2019

Evaluation of Gadopiclenol and P846, 2 High-Relaxivity Macrocyclic Magnetic Resonance Contrast Agents Without Protein Binding, in a Rodent Model of Hepatic Metastases: Potential Solutions for Improved Enhancement at Ultrahigh Field Strength.

Authors:
Peter Fries Alexander Massmann Philippe Robert Claire Corot Matthias W Laschke Günther Schneider Arno Buecker Andreas Müller

Invest Radiol 2019 Sep;54(9):549-558

From the Clinic for Diagnostic and Interventional Radiology, Saarland University Medical Center, Homburg, Germany.

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http://dx.doi.org/10.1097/RLI.0000000000000572DOI Listing
September 2019

The vasa vasorum reach deep into the human thoracic aorta.

Authors:
Jan Michael Federspiel Thomas Tschernig Matthias W Laschke Stefan Wagenpfeil Philipp Schnabel Hans-Joachim Schäfers

Ann Anat 2019 Sep 6;225:54-56. Epub 2019 Jul 6.

Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Faculty of Medicine, Saarland University, Campus Homburg/Saar, Saarland, Germany.

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http://dx.doi.org/10.1016/j.aanat.2019.06.001DOI Listing
September 2019

mRNA Binding Protein 2 Transgenic Mice Are More Prone to Develop a Ductular Reaction and to Progress Toward Cirrhosis.

Authors:
Beate Czepukojc Ali Abuhaliema Ahmad Barghash Sascha Tierling Norbert Naß Yvette Simon Christina Körbel Cristina Cadenas Noemi van Hul Agapios Sachinidis Jan G Hengstler Volkhard Helms Matthias W Laschke Jörn Walter Johannes Haybaeck Isabelle Leclercq Alexandra K Kiemer Sonja M Kessler

Front Med (Lausanne) 2019 4;6:179. Epub 2019 Sep 4.

Department of Pharmacy, Pharmaceutical Biology, Saarland University, Saarbrücken, Germany.

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http://dx.doi.org/10.3389/fmed.2019.00179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737005PMC
September 2019

Scratch Migration Assay and Dorsal Skinfold Chamber for In Vitro and In Vivo Analysis of Wound Healing.

Authors:
Anouar Belkacemi Matthias W Laschke Michael D Menger Veit Flockerzi

J Vis Exp 2019 Sep 26(151). Epub 2019 Sep 26.

Institute of Experimental and Clinical Pharmacology and Toxicology, Center for Molecular Signaling (PZMS), Saarland University.

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http://dx.doi.org/10.3791/59608DOI Listing
September 2019

The dorsal skinfold chamber: A valuable model for the in vivo evaluation of topical formulations.

Authors:
Indra N Dahmke Emmanuel Ampofo Michael D Menger Matthias W Laschke

Exp Dermatol 2019 Aug 4;28(8):940-947. Epub 2019 Jul 4.

Institute for Clinical & Experimental Surgery, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1111/exd.13983DOI Listing
August 2019

Distribution of the (synthetic) cannabinoids JWH-210, RCS-4, as well as ∆9-tetrahydrocannabinol following pulmonary administration to pigs.

Authors:
Nadine Schaefer Ann-Katrin Kröll Christina Körbel Matthias W Laschke Michael D Menger Hans H Maurer Markus R Meyer Peter H Schmidt

Arch Toxicol 2019 Aug 21;93(8):2211-2218. Epub 2019 Jun 21.

Institute of Legal Medicine, Saarland University, Building 49.1, 66421, Homburg, Saar, Germany.

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http://dx.doi.org/10.1007/s00204-019-02493-8DOI Listing
August 2019

Redox signals at the ER-mitochondria interface control melanoma progression.

Authors:
Xin Zhang Christine S Gibhardt Thorsten Will Hedwig Stanisz Christina Körbel Miso Mitkovski Ioana Stejerean Sabrina Cappello David Pacheu-Grau Jan Dudek Nasser Tahbaz Lucas Mina Thomas Simmen Matthias W Laschke Michael D Menger Michael P Schön Volkhard Helms Barbara A Niemeyer Peter Rehling Adina Vultur Ivan Bogeski

EMBO J 2019 Aug 15;38(15):e100871. Epub 2019 Jul 15.

Molecular Physiology, Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University, Göttingen, Germany.

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http://dx.doi.org/10.15252/embj.2018100871DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669928PMC
August 2019

Design, Synthesis, and Biological Characterization of Orally Active 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors Targeting the Prevention of Osteoporosis.

Authors:
Ahmed S Abdelsamie Mohamed Salah Lorenz Siebenbürger Ahmed Merabet Claudia Scheuer Martin Frotscher Sebastian T Müller Oliver Zierau Günter Vollmer Michael D Menger Matthias W Laschke Chris J van Koppen Sandrine Marchais-Oberwinkler Rolf W Hartmann

J Med Chem 2019 Aug 25;62(15):7289-7301. Epub 2019 Jul 25.

Department of Pharmaceutical and Medicinal Chemistry , Saarland University , 66123 Saarbrücken , Germany.

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https://pubs.acs.org/doi/10.1021/acs.jmedchem.9b00932
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http://dx.doi.org/10.1021/acs.jmedchem.9b00932DOI Listing
August 2019

Calligonum comosum (Escanbil) extract exerts anti-angiogenic, anti-proliferative and anti-inflammatory effects on endometriotic lesions.

Authors:
Kiandokht Kiani Jeannette Rudzitis-Auth Claudia Scheuer Mansoureh Movahedin Seyede Nargess Sadati Lamardi Hossein Malekafzali Ardakani Vivien Becker Ashraf Moini Reza Aflatoonian Seyed Nasser Ostad Michael D Menger Matthias W Laschke

J Ethnopharmacol 2019 Jul 26;239:111918. Epub 2019 Apr 26.

Institute for Clinical & Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jep.2019.111918DOI Listing
July 2019

University of Wisconsin solution for the xeno-free storage of adipose tissue-derived microvascular fragments.

Authors:
Matthias W Laschke Alexander Heß Claudia Scheuer Philipp Karschnia Elena Kontaxi Michael D Menger

Regen Med 2019 Jul 17;14(7):681-691. Epub 2019 Jul 17.

Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.2217/rme-2018-0164DOI Listing
July 2019

Profiling microRNA expression in murine bone healing and non-union formation: Role of miR-140 during the early stage of bone healing.

Authors:
Marcel Orth Claudia Scheuer Christina Backes Andreas Keller Mika F Rollmann Benedikt J Braun Nicole Ludwig Eckart Meese Tim Pohlemann Matthias W Laschke Michael D Menger Tina Histing

PLoS One 2019 19;14(7):e0218395. Epub 2019 Jul 19.

Department of Trauma, Hand and Reconstructive Surgery, Saarland University, Homburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0218395PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6641081PMC
July 2019

Soy Intake Since the Prepubertal Age May Contribute to the Pathogenesis of Endometriosis in Adulthood.

Authors:
Marie Alfrede Mvondo Jessica Darelle Ekenfack Stéphane Minko Essono Harding Saah Namekong Charline Florence Awounfack Matthias W Laschke Dieudonné Njamen

J Med Food 2019 Jun 13;22(6):631-638. Epub 2019 Mar 13.

2 Laboratory of Animal Physiology, University of Yaounde 1, Yaounde, Cameroon.

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http://dx.doi.org/10.1089/jmf.2018.0160DOI Listing
June 2019

miR-370 inhibits the angiogenic activity of endothelial cells by targeting smoothened (SMO) and bone morphogenetic protein (BMP)-2.

Authors:
Yuan Gu Vivien Becker Yingjun Zhao Michael D Menger Matthias W Laschke

FASEB J 2019 Jun 13;33(6):7213-7224. Epub 2019 Mar 13.

Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Germany; and.

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http://dx.doi.org/10.1096/fj.201802085RRDOI Listing
June 2019

The Evolution of Erythrocytes Becoming Red in Respect to Fluorescence.

Authors:
Laura Hertz Sandra Ruppenthal Greta Simionato Stephan Quint Alexander Kihm Asena Abay Polina Petkova-Kirova Ulrich Boehm Petra Weissgerber Christian Wagner Matthias W Laschke Lars Kaestner

Front Physiol 2019 19;10:753. Epub 2019 Jun 19.

Theoretical Medicine and Biosciences, Saarland University, Homburg, Germany.

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http://dx.doi.org/10.3389/fphys.2019.00753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6593091PMC
June 2019

Function of protein kinase CK2 in thrombus formation.

Authors:
Emmanuel Ampofo Beate M Schmitt Matthias W Laschke Michael D Menger

Platelets 2019 11;30(4):421-427. Epub 2018 Sep 11.

a Institute for Clinical & Experimental Surgery , Saarland University , Homburg/Saar , Germany.

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http://dx.doi.org/10.1080/09537104.2018.1513474DOI Listing
May 2019

Nerve/glial antigen 2 is crucially involved in the revascularization of freely transplanted pancreatic islets.

Authors:
Lisa Nalbach Beate M Schmitt Vivien Becker Anja Scheller Matthias W Laschke Michael D Menger Emmanuel Ampofo

Cell Tissue Res 2019 May 27. Epub 2019 May 27.

Institute for Clinical & Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.

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http://dx.doi.org/10.1007/s00441-019-03048-0DOI Listing
May 2019

VEGF-loaded mineral-coated microparticles improve bone repair and are associated with increased expression of epo and RUNX-2 in murine non-unions.

Authors:
Marcel Orth Amira K Shenar Claudia Scheuer Benedikt J Braun Steven C Herath Jörg H Holstein Tina Histing Xiaohua Yu William L Murphy Tim Pohlemann Matthias W Laschke Michael D Menger

J Orthop Res 2019 Apr 28;37(4):821-831. Epub 2019 Mar 28.

Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Germany.

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http://dx.doi.org/10.1002/jor.24267DOI Listing
April 2019

Maslinic acid alleviates ischemia/reperfusion-induced inflammation by downregulation of NFκB-mediated adhesion molecule expression.

Authors:
Emmanuel Ampofo Julian J Berg Michael D Menger Matthias W Laschke

Sci Rep 2019 Apr 16;9(1):6119. Epub 2019 Apr 16.

Institute for Clinical & Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.

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http://dx.doi.org/10.1038/s41598-019-42465-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467883PMC
April 2019

Microvascular Mechanisms of Polyphosphate-Induced Neutrophil-Endothelial Cell Interactions in vivo.

Authors:
Feifei Du Yongzhi Wang Zhiyi Ding Matthias W Laschke Henrik Thorlacius

Eur Surg Res 2019 25;60(1-2):53-62. Epub 2019 Mar 25.

Department of Clinical Sciences, Section of Surgery, Lund University, Malmö, Sweden,

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https://www.karger.com/Article/FullText/497435
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http://dx.doi.org/10.1159/000497435DOI Listing
March 2019

A murine model to study vasoreactivity and intravascular flow in lung isograft microvessels.

Authors:
Nora Regelin Susanne Heyder Matthias W Laschke Yalda Hadizamani Michèle Borgmann Ueli Moehrlen René Schramm Robert Bals Michael D Menger Jürg Hamacher

Sci Rep 2019 Mar 26;9(1):5170. Epub 2019 Mar 26.

Department of Internal Medicine V - Pulmonology, Allergology, Respiratory Intensive Care Medicine, Saarland University Hospital, 66424, Homburg, Germany.

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http://dx.doi.org/10.1038/s41598-019-41590-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6435642PMC
March 2019

Subnormothermic short-term cultivation improves the vascularization capacity of adipose tissue-derived microvascular fragments.

Authors:
Matthias W Laschke Alexander Heß Claudia Scheuer Philipp Karschnia Michael D Menger

J Tissue Eng Regen Med 2019 Feb 6;13(2):131-142. Epub 2019 Jan 6.

Institute for Clinical and Experimental Surgery, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1002/term.2774DOI Listing
February 2019

Targeted Endocrine Therapy: Design, Synthesis, and Proof-of-Principle of 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors in Bone Fracture Healing.

Authors:
Ahmed S Abdelsamie Steven Herath Yannik Biskupek Carsten Börger Lorenz Siebenbürger Mohamed Salah Claudia Scheuer Sandrine Marchais-Oberwinkler Martin Frotscher Tim Pohlemann Michael D Menger Rolf W Hartmann Matthias W Laschke Chris J van Koppen

J Med Chem 2019 Feb 15;62(3):1362-1372. Epub 2019 Jan 15.

ElexoPharm GmbH , Im Stadtwald, Building A1.2 , 66123 Saarbrücken , Germany.

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http://pubs.acs.org/doi/10.1021/acs.jmedchem.8b01493
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http://dx.doi.org/10.1021/acs.jmedchem.8b01493DOI Listing
February 2019

Retrieval of Migrated Volume Coils Using Different Clot Retrievers in a Porcine Model.

Authors:
Andreas Simgen Toshiki Tomori Ruben Mühl-Benninghaus Hagen Bomberg Umut Yilmaz Heiko Körner Matthias W Laschke Michael D Menger Wolfgang Reith

Clin Neuroradiol 2018 Dec 1;28(4):593-600. Epub 2017 Jun 1.

Department of Neuroradiology, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1007/s00062-017-0600-1DOI Listing
December 2018

Highly Potent 17β-HSD2 Inhibitors with a Promising Pharmacokinetic Profile for Targeted Osteoporosis Therapy.

Authors:
Lorenz Siebenbuerger Victor Hernandez-Olmos Ahmed S Abdelsamie Martin Frotscher Chris J van Koppen Sandrine Marchais-Oberwinkler Claudia Scheuer Matthias W Laschke Michael D Menger Carsten Boerger Rolf W Hartmann

J Med Chem 2018 12 27;61(23):10724-10738. Epub 2018 Nov 27.

Department of Pharmacy , Saarland University , Campus C2.3 , 66123 Saarbrücken , Germany.

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http://dx.doi.org/10.1021/acs.jmedchem.8b01373DOI Listing
December 2018

Marble-derived microcalcite improves bone healing in mice osteotomy.

Authors:
Marcel Orth Takhirjan Shadmanov Claudia Scheuer Benedikt J Braun Tobias Fritz Jörg H Holstein Tina Histing Matthias W Laschke Tim Pohlemann Michael D Menger

Biomed Mater 2018 12 7;14(2):025001. Epub 2018 Dec 7.

Department of Trauma, Hand and Reconstructive Surgery, Saarland University, Homburg, Germany. Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Germany.

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http://dx.doi.org/10.1088/1748-605X/aaee54DOI Listing
December 2018

In Vivo Biocompatibility of a Novel Expanded Polytetrafluoroethylene Suture for Annuloplasty.

Authors:
Daniel W Dudenhöffer Matthias W Laschke Christian Giebels Irem Karliova Ulrich Schneider Michael D Menger Hans-Joachim Schäfers

Thorac Cardiovasc Surg 2018 Nov 20. Epub 2018 Nov 20.

Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg, Germany.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1675595
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http://dx.doi.org/10.1055/s-0038-1675595DOI Listing
November 2018

Prevascularization of collagen-glycosaminoglycan scaffolds: stromal vascular fraction versus adipose tissue-derived microvascular fragments.

Authors:
Thomas Später Florian S Frueh Ruth M Nickels Michael D Menger Matthias W Laschke

J Biol Eng 2018 13;12:24. Epub 2018 Nov 13.

1Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1186/s13036-018-0118-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234670PMC
November 2018

Development of an In-vitro Drug Delivery Efficiency Test for a Pulmonary Toxicokinetic Pig Study.

Authors:
Nadine Schaefer Ann K Kroll Matthias W Laschke Michael D Menger Hans H Maurer Markus R Meyer Peter H Schmidt

Curr Drug Deliv 2018 ;15(8):1167-1171

Institute of Legal Medicine, Saarland University, Building 80.2, D-66421 Homburg (Saar), Germany.

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http://dx.doi.org/10.2174/1567201815666180214130014DOI Listing
October 2018

Can toxicokinetics of (synthetic) cannabinoids in pigs after pulmonary administration be upscaled to humans by allometric techniques?

Authors:
Nadine Schaefer Jan-Georg Wojtyniak Ann-Katrin Kroell Christina Koerbel Matthias W Laschke Thorsten Lehr Michael D Menger Hans H Maurer Markus R Meyer Peter H Schmidt

Biochem Pharmacol 2018 09 24;155:403-418. Epub 2018 Jul 24.

Institute of Legal Medicine, Saarland University, Building 80.2, D-66421 Homburg, Saar, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S00062952183029
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http://dx.doi.org/10.1016/j.bcp.2018.07.029DOI Listing
September 2018

Reply: Vascularization in endometriosis and its clinical applications.

Authors:
Matthias W Laschke Michael D Menger

Hum Reprod Update 2018 09;24(5):638

Institute for Clinical & Experimental Surgery, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1093/humupd/dmy024DOI Listing
September 2018

Targeting the Microcirculation by Indole-3-carbinol and Its Main Derivate 3,3,'-diindolylmethane: Effects on Angiogenesis, Thrombosis and Inflammation.

Authors:
Emmanuel Ampofo Beate M Schmitt Michael D Menger Matthias W Laschke

Mini Rev Med Chem 2018 ;18(11):962-968

Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.2174/1389557518666180313100144DOI Listing
July 2018

Effects of TGF-β Overexpression via rAAV Gene Transfer on the Early Repair Processes in an Osteochondral Defect Model in Minipigs.

Authors:
Magali Cucchiarini Ann-Kathrin Asen Lars Goebel Jagadeesh K Venkatesan Gertrud Schmitt David Zurakowski Michael D Menger Matthias W Laschke Henning Madry

Am J Sports Med 2018 07 24;46(8):1987-1996. Epub 2018 May 24.

Center of Experimental Orthopaedics, Saarland University Medical Center, Homburg/Saar, Germany.

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http://dx.doi.org/10.1177/0363546518773709DOI Listing
July 2018

Antimargination of Microparticles and Platelets in the Vicinity of Branching Vessels.

Authors:
Christian Bächer Alexander Kihm Lukas Schrack Lars Kaestner Matthias W Laschke Christian Wagner Stephan Gekle

Biophys J 2018 07;115(2):411-425

Biofluid Simulation and Modeling, Theoretische Physik, Universität Bayreuth, Bayreuth, Germany.

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http://dx.doi.org/10.1016/j.bpj.2018.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051480PMC
July 2018

Prevascularization of dermal substitutes with adipose tissue-derived microvascular fragments enhances early skin grafting.

Authors:
Florian S Frueh Thomas Später Christina Körbel Claudia Scheuer Anna C Simson Nicole Lindenblatt Pietro Giovanoli Michael D Menger Matthias W Laschke

Sci Rep 2018 Jul 20;8(1):10977. Epub 2018 Jul 20.

Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.

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http://dx.doi.org/10.1038/s41598-018-29252-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054621PMC
July 2018

Dual inhibition of PI3K and mTOR by VS-5584 suppresses thrombus formation.

Authors:
Thomas Später Isabelle Müller Hermann Eichler Michael D Menger Matthias W Laschke Emmanuel Ampofo

Platelets 2018 May 15;29(3):277-287. Epub 2017 May 15.

a Institute for Clinical & Experimental Surgery , Saarland University , Homburg/Saar , Germany.

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http://dx.doi.org/10.1080/09537104.2017.1306040DOI Listing
May 2018

Effects of cryopreservation on adipose tissue-derived microvascular fragments.

Authors:
Matthias W Laschke Philipp Karschnia Claudia Scheuer Alexander Heß Wolfgang Metzger Michael D Menger

J Tissue Eng Regen Med 2018 04 27;12(4):1020-1030. Epub 2017 Nov 27.

Institute for Clinical and Experimental Surgery, Saarland University, Homburg/Saar, Germany.

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http://doi.wiley.com/10.1002/term.2591
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http://dx.doi.org/10.1002/term.2591DOI Listing
April 2018

Distribution of Synthetic Cannabinoids JWH-210, RCS-4 and Δ 9-Tetrahydrocannabinol After Intravenous Administration to Pigs.

Authors:
Nadine Schaefer Mattias Kettner Matthias W Laschke Julia Schlote Andreas H Ewald Michael D Menger Hans H Maurer Peter H Schmidt

Curr Neuropharmacol 2017 ;15(5):713-723

Institute of Legal Medicine, Saarland University, Building 80.2, D-66421 Homburg (Saar). Germany.

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http://dx.doi.org/10.2174/1570159X15666161111114214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771047PMC
March 2018

Notch signaling controls sprouting angiogenesis of endometriotic lesions.

Authors:
Christina Körbel Miriam D Gerstner Michael D Menger Matthias W Laschke

Angiogenesis 2018 02 9;21(1):37-46. Epub 2017 Oct 9.

Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.

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http://dx.doi.org/10.1007/s10456-017-9580-7DOI Listing
February 2018

Inhibition of Cyclooxygenase-2 Suppresses the Recruitment of Endothelial Progenitor Cells in the Microvasculature of Endometriotic Lesions.

Authors:
Jeannette Rudzitis-Auth Ruth M Nickels Michael D Menger Matthias W Laschke

Am J Pathol 2018 02 13;188(2):450-460. Epub 2017 Dec 13.

Institute for Clinical & Experimental Surgery, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.ajpath.2017.10.013DOI Listing
February 2018

In vivo biocompatibility, vascularization, and incorporation of Integra dermal regenerative template and flowable wound matrix.

Authors:
Thomas Später Florian S Frueh Wolfgang Metzger Michael D Menger Matthias W Laschke

J Biomed Mater Res B Appl Biomater 2018 Jan 14;106(1):52-60. Epub 2016 Nov 14.

Institute for Clinical & Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.

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http://dx.doi.org/10.1002/jbm.b.33813DOI Listing
January 2018

Nerve/glial antigen (NG) 2 is a crucial regulator of intercellular adhesion molecule (ICAM)-1 expression.

Authors:
Beate M Schmitt Matthias W Laschke Oliver G Rössler Wenhui Huang Anja Scheller Michael D Menger Emmanuel Ampofo

Biochim Biophys Acta Mol Cell Res 2018 Jan 28;1865(1):57-66. Epub 2017 Sep 28.

Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2017.09.019DOI Listing
January 2018

Basic mechanisms of vascularization in endometriosis and their clinical implications.

Authors:
Matthias W Laschke Michael D Menger

Hum Reprod Update 2018 Jan 25. Epub 2018 Jan 25.

Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1093/humupd/dmy001DOI Listing
January 2018

IP Receptor-Dependent Cytoplasmic Ca Signals Are Tightly Controlled by Cavβ3.

Authors:
Anouar Belkacemi Xin Hui Barbara Wardas Matthias W Laschke Ulrich Wissenbach Michael D Menger Peter Lipp Andreas Beck Veit Flockerzi

Cell Rep 2018 01;22(5):1339-1349

Institut für Experimentelle und Klinische Pharmakologie und Toxikologie der Universität des Saarlandes, 66421 Homburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.01.010DOI Listing
January 2018

Enoxaparin does not affect network formation of adipose tissue-derived microvascular fragments.

Authors:
Thomas Später Florian S Frueh Philipp Karschnia Michael D Menger Matthias W Laschke

Wound Repair Regen 2018 01 25;26(1):36-45. Epub 2018 Mar 25.

Institute for Clinical & Experimental Surgery, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1111/wrr.12621DOI Listing
January 2018

Magnetic Resonance Lymphography at 9.4 T Using a Gadolinium-Based Nanoparticle in Rats: Investigations in Healthy Animals and in a Hindlimb Lymphedema Model.

Authors:
Andreas Müller Peter Fries Bijan Jelvani François Lux Claudia E Rübe Stephanie Kremp Pietro Giovanoli Arno Buecker Michael D Menger Matthias W Laschke Florian S Frueh

Invest Radiol 2017 12;52(12):725-733

From the *Clinic of Diagnostic and Interventional Radiology, Saarland University Medical Center, Homburg/Saar, Germany; †Institute for Clinical and Experimental Surgery, Saarland University, Homburg/Saar, Germany; ‡Institut Lumière Matière, Université Claude Bernard Lyon 1, CNRS, Lyon, France; §Department of Radiotherapy and Radiation Oncology, Saarland University Medical Center, Homburg/Saar, Germany; and ∥Division of Plastic Surgery and Hand Surgery, University Hospital Zürich, University of Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1097/RLI.0000000000000398DOI Listing
December 2017

Red Blood Cell Passage of Small Capillaries Is Associated with Transient Ca-mediated Adaptations.

Authors:
Jens G Danielczok Emmanuel Terriac Laura Hertz Polina Petkova-Kirova Franziska Lautenschläger Matthias W Laschke Lars Kaestner

Front Physiol 2017 5;8:979. Epub 2017 Dec 5.

Experimental Physics, Saarland University, Saarbrücken, Germany.

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http://dx.doi.org/10.3389/fphys.2017.00979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723316PMC
December 2017

Spheroids as vascularization units: From angiogenesis research to tissue engineering applications.

Authors:
Matthias W Laschke Michael D Menger

Biotechnol Adv 2017 Nov 8;35(6):782-791. Epub 2017 Jul 8.

Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.biotechadv.2017.07.002DOI Listing
November 2017

Bacterial keratitis: Photodynamic inactivation reduced experimental inflammation.

Authors:
Mona Deichelbohrer Ming-Feng Wu Berthold Seitz Dirk Hüttenberger Matthias W Laschke Hans-Jochen Foth Bodo Wonnenberg Stefan Wagenpfeil Carola Meier Markus Bischoff Thomas Tschernig

Exp Ther Med 2017 Nov 5;14(5):4509-4514. Epub 2017 Sep 5.

Institute of Anatomy and Cell Biology, Medical Faculty, Saarland University, D-66424 Homburg/Saar, Germany.

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http://dx.doi.org/10.3892/etm.2017.5109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658727PMC
November 2017

Mechanical and biological characterization of alkaline substituted orthophosphate bone substitutes containing meta- and diphosphates.

Authors:
Moritz Klein Matthias W Laschke Jörg H Holstein Tina Histing Tim Pohlemann Michael D Menger Patric Garcia

Biomed Mater 2017 Sep 25;12(5):055007. Epub 2017 Sep 25.

Department of Trauma-, Hand- and Reconstructive Surgery, Saarland University, Kirrberger Str. 1, D-66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1088/1748-605X/aa7e80DOI Listing
September 2017

Current and emerging vascularization strategies in skin tissue engineering.

Authors:
Florian S Frueh Michael D Menger Nicole Lindenblatt Pietro Giovanoli Matthias W Laschke

Crit Rev Biotechnol 2017 Aug 20;37(5):613-625. Epub 2016 Jul 20.

a Institute for Clinical and Experimental Surgery , Saarland University , Homburg (Saar) , Germany.

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http://dx.doi.org/10.1080/07388551.2016.1209157DOI Listing
August 2017

miR-191 suppresses angiogenesis by activation of NF-κB signaling.

Authors:
Yuan Gu Emmanuel Ampofo Michael D Menger Matthias W Laschke

FASEB J 2017 08 19;31(8):3321-3333. Epub 2017 Apr 19.

Institute for Clinical and Experimental Surgery, Saarland University, Homburg/Saar, Germany

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http://dx.doi.org/10.1096/fj.201601263RDOI Listing
August 2017

The regulatory mechanisms of NG2/CSPG4 expression.

Authors:
Emmanuel Ampofo Beate M Schmitt Michael D Menger Matthias W Laschke

Cell Mol Biol Lett 2017 28;22. Epub 2017 Feb 28.

Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg, Germany.

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http://dx.doi.org/10.1186/s11658-017-0035-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5415841PMC
August 2017

Combination therapy with telmisartan and parecoxib induces regression of endometriotic lesions.

Authors:
Anca Nenicu Yuan Gu Christina Körbel Michael D Menger Matthias W Laschke

Br J Pharmacol 2017 Aug 6;174(16):2623-2635. Epub 2017 Jul 6.

Institute for Clinical & Experimental Surgery, Saarland University, Homburg/Saar, Germany.

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http://doi.wiley.com/10.1111/bph.13874
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522992PMC
August 2017

Indole-3-carbinol is a potent inhibitor of ischemia-reperfusion-induced inflammation.

Authors:
Emmanuel Ampofo Nico Lachnitt Jeannette Rudzitis-Auth Beate M Schmitt Michael D Menger Matthias W Laschke

J Surg Res 2017 07 31;215:34-46. Epub 2017 Mar 31.

Institute for Clinical & Experimental Surgery, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.jss.2017.03.019DOI Listing
July 2017

Lead Optimization Generates CYP11B1 Inhibitors of Pyridylmethyl Isoxazole Type with Improved Pharmacological Profile for the Treatment of Cushing's Disease.

Authors:
Juliette Emmerich Chris J van Koppen Jens L Burkhart Qingzhong Hu Lorenz Siebenbürger Carsten Boerger Claudia Scheuer Matthias W Laschke Michael D Menger Rolf W Hartmann

J Med Chem 2017 06 9;60(12):5086-5098. Epub 2017 Jun 9.

Pharmaceutical and Medicinal Chemistry, Saarland University , Campus E8.1, 66123 Saarbrücken, Germany.

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http://dx.doi.org/10.1021/acs.jmedchem.7b00437DOI Listing
June 2017

Protein Kinase CK2 Regulates Leukocyte-Endothelial Cell Interactions during Ischemia and Reperfusion in Striated Skin Muscle.

Authors:
Emmanuel Ampofo Daniela Widmaier Mathias Montenarh Michael D Menger Matthias W Laschke

Eur Surg Res 2016 8;57(1-2):111-24. Epub 2016 Jun 8.

Institute for Clinical and Experimental Surgery, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1159/000446367DOI Listing
April 2017

Metabolic patterns of JWH-210, RCS-4, and THC in pig urine elucidated using LC-HR-MS/MS: Do they reflect patterns in humans?

Authors:
Nadine Schaefer Andreas G Helfer Mattias Kettner Matthias W Laschke Julia Schlote Andreas H Ewald Markus R Meyer Michael D Menger Hans H Maurer Peter H Schmidt

Drug Test Anal 2017 Apr 22;9(4):613-625. Epub 2016 Jun 22.

Institute of Legal Medicine, Saarland University, Building 80.2, D-66421, Homburg (Saar), Germany.

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http://dx.doi.org/10.1002/dta.1995DOI Listing
April 2017

Isolation of Murine Adipose Tissue-derived Microvascular Fragments as Vascularization Units for Tissue Engineering.

Authors:
Florian S Frueh Thomas Später Claudia Scheuer Michael D Menger Matthias W Laschke

J Vis Exp 2017 04 30(122). Epub 2017 Apr 30.

Institute for Clinical and Experimental Surgery, Saarland University.

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https://www.jove.com/video/55721/isolation-murine-adipose-ti
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http://dx.doi.org/10.3791/55721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565147PMC
April 2017

Chlorin e6 mediated photodynamic inactivation for multidrug resistant Pseudomonas aeruginosa keratitis in mice in vivo.

Authors:
Ming-Feng Wu Mona Deichelbohrer Thomas Tschernig Matthias W Laschke Nóra Szentmáry Dirk Hüttenberger Hans-Jochen Foth Berthold Seitz Markus Bischoff

Sci Rep 2017 03 15;7:44537. Epub 2017 Mar 15.

Institute for Medical Microbiology and Hygiene, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1038/srep44537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353637PMC
March 2017

Life is 3D: Boosting Spheroid Function for Tissue Engineering.

Authors:
Matthias W Laschke Michael D Menger

Trends Biotechnol 2017 02 12;35(2):133-144. Epub 2016 Sep 12.

Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.tibtech.2016.08.004DOI Listing
February 2017

Treatment of estrogen-dependent diseases: Design, synthesis and profiling of a selective 17β-HSD1 inhibitor with sub-nanomolar IC for a proof-of-principle study.

Authors:
Ahmed S Abdelsamie Chris J van Koppen Emmanuel Bey Mohamed Salah Carsten Börger Lorenz Siebenbürger Matthias W Laschke Michael D Menger Martin Frotscher

Eur J Med Chem 2017 Feb 4;127:944-957. Epub 2016 Nov 4.

Pharmaceutical and Medicinal Chemistry, Saarland University, Campus C23, D-66123 Saarbrücken, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2016.11.004DOI Listing
February 2017

Adipose Tissue-Derived Microvascular Fragments Improve Vascularization, Lymphangiogenesis, and Integration of Dermal Skin Substitutes.

Authors:
Florian S Frueh Thomas Später Nicole Lindenblatt Maurizio Calcagni Pietro Giovanoli Claudia Scheuer Michael D Menger Matthias W Laschke

J Invest Dermatol 2017 01 26;137(1):217-227. Epub 2016 Aug 26.

Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.jid.2016.08.010DOI Listing
January 2017

Perigraft vascularization and incorporation of implanted Dacron prostheses are affected by rifampicin coating.

Authors:
Mohammed R Moussavian Matthias W Laschke Georg Schlachtenberger Maximilian von Heesen Matthias Wagner Matthias Glanemann Michael D Menger

J Vasc Surg 2016 Dec 19;64(6):1815-1824. Epub 2015 Nov 19.

Institute for Clinical and Experimental Surgery, Saarland University, Homburg, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S07415214150197
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http://dx.doi.org/10.1016/j.jvs.2015.07.104DOI Listing
December 2016

Prevascularization in tissue engineering: Current concepts and future directions.

Authors:
Matthias W Laschke Michael D Menger

Biotechnol Adv 2016 Mar-Apr;34(2):112-21. Epub 2015 Dec 7.

Institute for Clinical & Experimental Surgery, Saarland University, D-66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.biotechadv.2015.12.004DOI Listing
November 2016

Surface modification by plasma etching impairs early vascularization and tissue incorporation of porous polyethylene (Medpor ) implants.

Authors:
Matthias W Laschke Victor A Augustin Fadime Sahin Dieter Anschütz Wolfgang Metzger Claudia Scheuer Markus Bischoff Cenk Aktas Michael D Menger

J Biomed Mater Res B Appl Biomater 2016 11 10;104(8):1738-1748. Epub 2015 Sep 10.

Institute for Clinical & Experimental Surgery, Saarland University, 66421, Homburg/Saar, Germany.

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http://dx.doi.org/10.1002/jbm.b.33528DOI Listing
November 2016

High-resolution 3D volumetry versus conventional measuring techniques for the assessment of experimental lymphedema in the mouse hindlimb.

Authors:
Florian S Frueh Christina Körbel Laura Gassert Andreas Müller Epameinondas Gousopoulos Nicole Lindenblatt Pietro Giovanoli Matthias W Laschke Michael D Menger

Sci Rep 2016 10 4;6:34673. Epub 2016 Oct 4.

Institute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1038/srep34673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048170PMC
October 2016

Inhibition of Hyaluronic Acid Synthesis Suppresses Angiogenesis in Developing Endometriotic Lesions.

Authors:
Carla N Olivares Laura D Alaniz Michael D Menger Rosa I Barañao Matthias W Laschke Gabriela F Meresman

PLoS One 2016 28;11(3):e0152302. Epub 2016 Mar 28.

Instituto de Biología y Medicina Experimental (IBYME-CONICET), Ciudad Autónoma de Buenos Aires, Argentina.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152302PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809563PMC
August 2016

Estrogen Stimulates Homing of Endothelial Progenitor Cells to Endometriotic Lesions.

Authors:
Jeannette Rudzitis-Auth Anca Nenicu Ruth M Nickels Michael D Menger Matthias W Laschke

Am J Pathol 2016 08 14;186(8):2129-2142. Epub 2016 Jun 14.

Institute for Clinical and Experimental Surgery, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.ajpath.2016.04.004DOI Listing
August 2016

The gut microbiota: a puppet master in the pathogenesis of endometriosis?

Authors:
Matthias W Laschke Michael D Menger

Am J Obstet Gynecol 2016 07 18;215(1):68.e1-4. Epub 2016 Feb 18.

Institute for Clinical & Experimental Surgery, Saarland University, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.ajog.2016.02.036DOI Listing
July 2016

Portal Hyperperfusion after Extended Hepatectomy Does Not Induce a Hepatic Arterial Buffer Response (HABR) but Impairs Mitochondrial Redox State and Hepatocellular Oxygenation.

Authors:
Stefan Dold Sven Richter Otto Kollmar Maximilian von Heesen Claudia Scheuer Matthias W Laschke Brigitte Vollmar Martin K Schilling Michael D Menger

PLoS One 2015 2;10(11):e0141877. Epub 2015 Nov 2.

Institute for Clinical & Experimental Surgery, University of Saarland, Homburg/Saar, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0141877PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4629903PMC
June 2016

Pharmacokinetics of (synthetic) cannabinoids in pigs and their relevance for clinical and forensic toxicology.

Authors:
Nadine Schaefer Jan-Georg Wojtyniak Mattias Kettner Julia Schlote Matthias W Laschke Andreas H Ewald Thorsten Lehr Michael D Menger Hans H Maurer Peter H Schmidt

Toxicol Lett 2016 Jun 23;253:7-16. Epub 2016 Apr 23.

Institute of Legal Medicine, Saarland University, Building 80.2, D-66421 Homburg, Saarland, Germany.

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http://dx.doi.org/10.1016/j.toxlet.2016.04.021DOI Listing
June 2016

Bioengineered vascular grafts off the shelf.

Authors:
Matthias W Laschke Michael D Menger

Lancet 2016 May;387(10032):1976-8

Institute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/S0140-6736(16)30180-5DOI Listing
May 2016

Geraniol Suppresses Angiogenesis by Downregulating Vascular Endothelial Growth Factor (VEGF)/VEGFR-2 Signaling.

Authors:
Christine Wittig Claudia Scheuer Julia Parakenings Michael D Menger Matthias W Laschke

PLoS One 2015 8;10(7):e0131946. Epub 2015 Jul 8.

Institute for Clinical & Experimental Surgery, University of Saarland, Homburg/Saar, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131946PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4496091PMC
April 2016

Initial Host Response to Bacteria in the Murine Lung Differs Between Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae.

Authors:
Liselotte Preu Markus Bischoff Nils T Veith Martin Rosenbruch Dirk Theegarten Matthias W Laschke Carola Meier Thomas Tschernig

Inflammation 2016 Apr;39(2):513-7

Institute for Anatomy and Cell Biology, Saarland University, Kirrberger Strasse, 66421, Homburg, Saar, Germany.

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http://dx.doi.org/10.1007/s10753-015-0274-2DOI Listing
April 2016

Tubeimoside-1 suppresses tumor angiogenesis by stimulation of proteasomal VEGFR2 and Tie2 degradation in a non-small cell lung cancer xenograft model.

Authors:
Yuan Gu Christina Körbel Claudia Scheuer Anca Nenicu Michael D Menger Matthias W Laschke

Oncotarget 2016 Feb;7(5):5258-72

Institute for Clinical & Experimental Surgery, Saarland University, Homburg/Saar 66421, Germany.

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http://dx.doi.org/10.18632/oncotarget.6676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4868684PMC
February 2016

Endothelin-1-induced remodelling of murine adult ventricular myocytes.

Authors:
Cedric Viero Silke Wegener Anke Scholz Sandra Ruppenthal Qinghai Tian Wiebke Tabellion Michael Kreinest Matthias W Laschke Lars Kaestner Peter Lipp

Cell Calcium 2016 Jan 5;59(1):41-53. Epub 2016 Jan 5.

Institute for Molecular Cell Biology, School of Medicine, Saarland University, Building 61, 66421 Homburg/Saar, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ceca.2015.12.005DOI Listing
January 2016

Role of protein kinase CK2 in the dynamic interaction of platelets, leukocytes and endothelial cells during thrombus formation.

Authors:
Emmanuel Ampofo Isabelle Müller Indra N Dahmke Hermann Eichler Mathias Montenarh Michael D Menger Matthias W Laschke

Thromb Res 2015 Nov 3;136(5):996-1006. Epub 2015 Sep 3.

Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.thromres.2015.08.023DOI Listing
November 2015

The Marine-Derived Kinase Inhibitor Fascaplysin Exerts Anti-Thrombotic Activity.

Authors:
Emmanuel Ampofo Thomas Später Isabelle Müller Hermann Eichler Michael D Menger Matthias W Laschke

Mar Drugs 2015 Nov 9;13(11):6774-91. Epub 2015 Nov 9.

Institute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.3390/md13116774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4663553PMC
November 2015

Inhibition of protein kinase CK2 suppresses tumor necrosis factor (TNF)-α-induced leukocyte-endothelial cell interaction.

Authors:
Emmanuel Ampofo Jeannette Rudzitis-Auth Indra N Dahmke Oliver G Rössler Gerald Thiel Mathias Montenarh Michael D Menger Matthias W Laschke

Biochim Biophys Acta 2015 Oct 17;1852(10 Pt A):2123-36. Epub 2015 Jul 17.

Institute for Clinical & Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.bbadis.2015.07.013DOI Listing
October 2015

Mesenchymal-endothelial transition in juvenile angiofibroma?

Authors:
Philipp Kulas Vivienne Willnecker Julia Dlugaiczyk Matthias W Laschke Bernhard Schick

Acta Otolaryngol 2015 Sep 7;135(9):955-61. Epub 2015 May 7.

Department of Otorhinolaryngology, Saarland University Medical Center , Homburg/Saar , Germany.

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http://dx.doi.org/10.3109/00016489.2015.1042042DOI Listing
September 2015

Adipose tissue-derived microvascular fragments: natural vascularization units for regenerative medicine.

Authors:
Matthias W Laschke Michael D Menger

Trends Biotechnol 2015 Aug 30;33(8):442-8. Epub 2015 Jun 30.

Institute for Clinical and Experimental Surgery, Saarland University, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.tibtech.2015.06.001DOI Listing
August 2015

Simultaneous LC-MS/MS determination of JWH-210, RCS-4, ∆(9)-tetrahydrocannabinol, and their main metabolites in pig and human serum, whole blood, and urine for comparing pharmacokinetic data.

Authors:
Nadine Schaefer Mattias Kettner Matthias W Laschke Julia Schlote Benjamin Peters Dietmar Bregel Michael D Menger Hans H Maurer Andreas H Ewald Peter H Schmidt

Anal Bioanal Chem 2015 May 15;407(13):3775-86. Epub 2015 Mar 15.

Institute of Legal Medicine, Saarland University, Building 80.2, 66421, Homburg, Saar, Germany.

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http://dx.doi.org/10.1007/s00216-015-8605-6DOI Listing
May 2015

Vascular and neural stem cells in the gut: do they need each other?

Authors:
Sandra Schrenk Anne Schuster Markus Klotz Franziska Schleser Jonathan Lake Robert O Heuckeroth Yoo-Jin Kim Matthias W Laschke Michael D Menger Karl-Herbert Schäfer

Histochem Cell Biol 2015 Apr 5;143(4):397-410. Epub 2014 Nov 5.

Department of Computer Sciences and Microsystem Technology, University of Applied Sciences Kaiserslautern, Zweibrücken, Germany.

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http://dx.doi.org/10.1007/s00418-014-1288-9DOI Listing
April 2015

In vitro osteogenic differentiation of adipose-derived mesenchymal stem cell spheroids impairs their in vivo vascularization capacity inside implanted porous polyurethane scaffolds.

Authors:
Matthias W Laschke Timo E Schank Claudia Scheuer Sascha Kleer Takhirjan Shadmanov David Eglin Mauro Alini Michael D Menger

Acta Biomater 2014 Oct 3;10(10):4226-35. Epub 2014 Jul 3.

Institute for Clinical & Experimental Surgery, University of Saarland, 66421 Homburg/Saar, Germany; Collaborative Research Partner Large Bone Defect Healing Program of AO Foundation, Switzerland.

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http://dx.doi.org/10.1016/j.actbio.2014.06.035DOI Listing
October 2014

Curcumin intake affects miRNA signature in murine melanoma with mmu-miR-205-5p most significantly altered.

Authors:
Indra N Dahmke Christina Backes Jeannette Rudzitis-Auth Matthias W Laschke Petra Leidinger Michael D Menger Eckart Meese Ulrich Mahlknecht

PLoS One 2013 12;8(12):e81122. Epub 2013 Dec 12.

Department for Internal Medicine - Hematology/Oncology, St. Lukas Klinik, Solingen, Germany ; Department of Internal Medicine, Division of Immunotherapy and Gene Therapy, Saarland University Medical Center, Homburg/Saar, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0081122PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861310PMC
September 2014

Human umbilical cord blood mononuclear cells in a double-hit model of bronchopulmonary dysplasia in neonatal mice.

Authors:
Dominik Monz Erol Tutdibi Céline Mildau Jie Shen Mariz Kasoha Matthias W Laschke Torge Roolfs Andreas Schmiedl Thomas Tschernig Karen Bieback Ludwig Gortner

PLoS One 2013 19;8(9):e74740. Epub 2013 Sep 19.

Department of Pediatrics and Neonatology, Saarland University, Homburg, Saar, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074740PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778007PMC
June 2014

Incorporation of bone marrow cells in pancreatic pseudoislets improves posttransplant vascularization and endocrine function.

Authors:
Christine Wittig Matthias W Laschke Claudia Scheuer Michael D Menger

PLoS One 2013 18;8(7):e69975. Epub 2013 Jul 18.

Institute for Clinical & Experimental Surgery, University of Saarland, Homburg/Saar, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0069975PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715469PMC
February 2014

Luminal epithelium in endometrial fragments affects their vascularization, growth and morphological development into endometriosis-like lesions in mice.

Authors:
Dilu Feng Michael D Menger Hongbo Wang Matthias W Laschke

Dis Model Mech 2014 Feb 28;7(2):225-32. Epub 2013 Nov 28.

Institute for Clinical & Experimental Surgery, University of Saarland, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1242/dmm.013664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3917243PMC
February 2014

Silver acetate coating promotes early vascularization of Dacron vascular grafts without inducing host tissue inflammation.

Authors:
Pascal Jeanmonod Matthias W Laschke Nils Gola Maximilian von Heesen Matthias Glanemann Stefan Dold Michael D Menger Mohammed R Moussavian

J Vasc Surg 2013 Dec 15;58(6):1637-43. Epub 2013 May 15.

Department of General, Visceral, Vascular and Pediatric Surgery, University of Saarland, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.jvs.2013.02.012DOI Listing
December 2013

Glucose regulates protein kinase CK2 in pancreatic β-cells and its interaction with PDX-1.

Authors:
Sabrina Welker Claudia Götz Christina Servas Matthias W Laschke Michael D Menger Mathias Montenarh

Int J Biochem Cell Biol 2013 Dec 12;45(12):2786-95. Epub 2013 Oct 12.

Medical Biochemistry and Molecular Biology, Saarland University, Building 44, D-66424 Homburg, Germany.

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http://dx.doi.org/10.1016/j.biocel.2013.10.002DOI Listing
December 2013

Vascular disrupting effects of combretastatin A4 phosphate on murine endometriotic lesions.

Authors:
Dilu Feng Michael D Menger Matthias W Laschke

Fertil Steril 2013 Nov 28;100(5):1459-67. Epub 2013 Aug 28.

Institute for Clinical and Experimental Surgery, University of Saarland, Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.fertnstert.2013.07.1967DOI Listing
November 2013

Direct visualisation of microparticles in the living lung.

Authors:
Thomas Tschernig Nils T Veith René Schramm Matthias W Laschke Jonas Roller Martin Rosenbruch Dirk Theegarten Markus Bischoff Carola Meier Michael D Menger

Exp Toxicol Pathol 2013 Sep 11;65(6):883-6. Epub 2013 Jan 11.

Institute of Anatomy and Cell Biology, Saarland University, Medical Faculty, Kirrberger Strasse, D-66421 Homburg, Saar, Germany.

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http://dx.doi.org/10.1016/j.etp.2012.12.007DOI Listing
September 2013

Inhibition of angiogenesis: a novel antitumor mechanism of the herbal compound arctigenin.

Authors:
Yuan Gu Claudia Scheuer Dilu Feng Michael D Menger Matthias W Laschke

Anticancer Drugs 2013 Sep;24(8):781-91

Institute for Clinical and Experimental Surgery, University of Saarland, Homburg/Saar, Germany.

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http://dx.doi.org/10.1097/CAD.0b013e328362fb84DOI Listing
September 2013

Bronchopulmonary dysplasia in a double-hit mouse model induced by intrauterine hypoxia and postnatal hyperoxia: closer to clinical features?

Authors:
Ludwig Gortner Dominik Monz Céline Mildau Jie Shen Mariz Kasoha Matthias W Laschke Torge Roolfs Andreas Schmiedl Carola Meier Erol Tutdibi

Ann Anat 2013 Jul 20;195(4):351-8. Epub 2013 Apr 20.

Department of Pediatrics and Neonatology, Saarland University, Homburg, Saar, Germany.

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http://dx.doi.org/10.1016/j.aanat.2013.02.010DOI Listing
July 2013

Ultralarge von Willebrand factor fibers mediate luminal Staphylococcus aureus adhesion to an intact endothelial cell layer under shear stress.

Authors:
Karin I Pappelbaum Christian Gorzelanny Sandra Grässle Jan Suckau Matthias W Laschke Markus Bischoff Corinne Bauer Marina Schorpp-Kistner Christopher Weidenmaier Reinhard Schneppenheim Tobias Obser Bhanu Sinha Stefan W Schneider

Circulation 2013 Jul 29;128(1):50-9. Epub 2013 May 29.

Experimental Dermatology, Department of Dermatology, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.002008DOI Listing
July 2013

4-hydroxybenzyl alcohol: a novel inhibitor of tumor angiogenesis and growth.

Authors:
Matthias W Laschke Antonia E Vorsterman van Oijen Christina Körbel Claudia Scheuer Michael D Menger

Life Sci 2013 Jul 3;93(1):44-50. Epub 2013 Jun 3.

Institute for Clinical & Experimental Surgery, University of Saarland, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.lfs.2013.05.022DOI Listing
July 2013

Regional treatment with liquid barrier agents: a novel therapeutic option for intraperitoneal endometriosis?

Authors:
Matthias W Laschke Jeannette Rudzitis-Auth Michael D Menger

Med Hypotheses 2013 Jun 19;80(6):709-10. Epub 2013 Mar 19.

Institute for Clinical and Experimental Surgery, University of Saarland, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.mehy.2013.02.016DOI Listing
June 2013

Overcoming intrinsic multidrug resistance in melanoma by blocking the mitochondrial respiratory chain of slow-cycling JARID1B(high) cells.

Authors:
Alexander Roesch Adina Vultur Ivan Bogeski Huan Wang Katharina M Zimmermann David Speicher Christina Körbel Matthias W Laschke Phyllis A Gimotty Stephan E Philipp Elmar Krause Sylvie Pätzold Jessie Villanueva Clemens Krepler Mizuho Fukunaga-Kalabis Markus Hoth Boris C Bastian Thomas Vogt Meenhard Herlyn

Cancer Cell 2013 Jun;23(6):811-25

Department of Dermatology, The Saarland University Hospital, D-66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1016/j.ccr.2013.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3810180PMC
June 2013

Two-step labeling of Staphylococcus aureus with Lysostaphin-Azide and DIBO-Alexa using click chemistry.

Authors:
Inga Potapova David Eglin Matthias W Laschke Markus Bischoff R Geoff Richards T Fintan Moriarty

J Microbiol Methods 2013 Jan 13;92(1):90-8. Epub 2012 Nov 13.

AO Research Institute Davos, Clavadelerstrasse 8, 7270 Davos Platz, Switzerland.

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http://dx.doi.org/10.1016/j.mimet.2012.11.004DOI Listing
January 2013