Matthias Mann

Matthias Mann

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Matthias Mann

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Plasma Proteome Profiling to detect and avoid sample-related biases in biomarker studies.

EMBO Mol Med 2019 Nov 30;11(11):e10427. Epub 2019 Sep 30.

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

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http://dx.doi.org/10.15252/emmm.201910427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835559PMC
November 2019

SILAC-based quantitative proteomics using mass spectrometry quantifies endoplasmic reticulum stress in whole HeLa cells.

Dis Model Mech 2019 Nov 11;12(11). Epub 2019 Nov 11.

Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, 82152 Martinsried, Germany

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http://dx.doi.org/10.1242/dmm.040741DOI Listing
November 2019

Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine.

Cell Metab 2019 Nov 24;30(5):963-975.e7. Epub 2019 Oct 24.

Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark; The Centre of Inflammation and Metabolism and the Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.10.001DOI Listing
November 2019

Sleep-wake cycles drive daily dynamics of synaptic phosphorylation.

Science 2019 10;366(6462)

Institute of Medical Psychology, Faculty of Medicine, LMU Munich, Germany.

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http://dx.doi.org/10.1126/science.aav3617DOI Listing
October 2019

Response to Raaijmakers & Medema.

EMBO J 2019 Oct 22:e103547. Epub 2019 Oct 22.

Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.15252/embj.2019103547DOI Listing
October 2019

The ever expanding scope of electrospray mass spectrometry-a 30 year journey.

Authors:
Matthias Mann

Nat Commun 2019 Sep 9;10(1):3744. Epub 2019 Sep 9.

Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

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http://dx.doi.org/10.1038/s41467-019-11747-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733869PMC
September 2019

Metallopeptidase inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer.

Mol Oncol 2019 Sep 23. Epub 2019 Sep 23.

Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

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http://dx.doi.org/10.1002/1878-0261.12575DOI Listing
September 2019

Myosin binding protein H-like (MYBPHL): a promising biomarker to predict atrial damage.

Sci Rep 2019 Jul 10;9(1):9986. Epub 2019 Jul 10.

Department of Cardiovascular Surgery, Division of Experimental Surgery, Institute Insure (Institute for Translational Cardiac Surgery), German Heart Center Munich at the Technical University of Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41598-019-46123-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6620353PMC
July 2019

Phosphoproteomics Reveals the GSK3-PDX1 Axis as a Key Pathogenic Signaling Node in Diabetic Islets.

Cell Metab 2019 Jun 14;29(6):1422-1432.e3. Epub 2019 Mar 14.

Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, 82152 Martinsried, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.02.012DOI Listing
June 2019

MaxQuant.Live Enables Global Targeting of More Than 25,000 Peptides.

Mol Cell Proteomics 2019 05 12;18(5):982-994. Epub 2019 Feb 12.

§Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany;

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http://dx.doi.org/10.1074/mcp.TIR118.001131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495250PMC
May 2019

Multi-omic Profiling Reveals Dynamics of the Phased Progression of Pluripotency.

Cell Syst 2019 May 8;8(5):427-445.e10. Epub 2019 May 8.

Epigenetics & Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24054712193011
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http://dx.doi.org/10.1016/j.cels.2019.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6544180PMC
May 2019

Phosphoproteomic approach for agonist-specific signaling in mouse brains: mTOR pathway is involved in κ opioid aversion.

Neuropsychopharmacology 2019 04 20;44(5):939-949. Epub 2018 Jul 20.

Center for Substance Abuse Research & Department of Pharmacology, Temple University Lewis Katz School of Medicine, Philadelphia, PA, 19140, USA.

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http://dx.doi.org/10.1038/s41386-018-0155-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462019PMC
April 2019

Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex.

EMBO J 2019 Apr 19;38(7). Epub 2019 Feb 19.

Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

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https://onlinelibrary.wiley.com/doi/abs/10.15252/embj.201810
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http://dx.doi.org/10.15252/embj.2018100977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443202PMC
April 2019

The Case for Proteomics and Phospho-Proteomics in Personalized Cancer Medicine.

Proteomics Clin Appl 2019 03;13(2):e1800113

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152, Martinsried, Germany.

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http://dx.doi.org/10.1002/prca.201800113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519247PMC
March 2019

Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts.

Mol Cell 2019 02 27;73(3):574-588.e7. Epub 2018 Dec 27.

Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, DK-2200 Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375733PMC
February 2019

The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair.

Cell 2019 01 27;176(1-2):167-181.e21. Epub 2018 Dec 27.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Howard Hughes Medical Institute, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.10.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475077PMC
January 2019

Catching Lipid Droplet Contacts by Proteomics.

Contact (Thousand Oaks) 2019 Jan 4;2:2515256419859186. Epub 2019 Jul 4.

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

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http://dx.doi.org/10.1177/2515256419859186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660307PMC
January 2019

Online Parallel Accumulation-Serial Fragmentation (PASEF) with a Novel Trapped Ion Mobility Mass Spectrometer.

Mol Cell Proteomics 2018 12 1;17(12):2534-2545. Epub 2018 Nov 1.

From the ‡Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany;

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http://dx.doi.org/10.1074/mcp.TIR118.000900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283298PMC
December 2018

Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery.

Cell Syst 2018 12 5;7(6):601-612.e3. Epub 2018 Dec 5.

Faculty of Health and Medical Sciences, NNF Center for Protein Research, University of Copenhagen, Copenhagen, Denmark; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2018.10.012DOI Listing
December 2018

Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis.

Dev Cell 2018 10;47(2):205-221.e7

Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried 82152, Germany; Faculty of Health Sciences, NNF Center for Protein Research, University of Copenhagen, Copenhagen 2200, Denmark. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15345807183077
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http://dx.doi.org/10.1016/j.devcel.2018.09.017DOI Listing
October 2018

High-throughput and high-sensitivity phosphoproteomics with the EasyPhos platform.

Nat Protoc 2018 09;13(9):1897-1916

Max Planck Institute of Biochemistry, Martinsried, Germany.

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http://www.nature.com/articles/s41596-018-0014-9
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http://dx.doi.org/10.1038/s41596-018-0014-9DOI Listing
September 2018

The Transcription Factor ETV1 Induces Atrial Remodeling and Arrhythmia.

Circ Res 2018 08;123(5):550-563

From the Institute of Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine (C.R., S.R., A.L., M.B., M.S., R.G., T.B., T.S., S.M., L.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.118.313036DOI Listing
August 2018

Proteomics for blood biomarker exploration of severe mental illness: pitfalls of the past and potential for the future.

Transl Psychiatry 2018 08 16;8(1):160. Epub 2018 Aug 16.

Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital Munich, LMU, 80336, Munich, Germany.

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http://dx.doi.org/10.1038/s41398-018-0219-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6095863PMC
August 2018

The hemicellulose-degrading enzyme system of the thermophilic bacterium : comparative characterisation and addition of new hemicellulolytic glycoside hydrolases.

Biotechnol Biofuels 2018 23;11:229. Epub 2018 Aug 23.

1Department of Microbiology, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Emil-Ramann-Str. 4, 85354 Freising, Germany.

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http://dx.doi.org/10.1186/s13068-018-1228-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106730PMC
August 2018

EASI-tag enables accurate multiplexed and interference-free MS2-based proteome quantification.

Nat Methods 2018 07 18;15(7):527-530. Epub 2018 Jun 18.

Experimental Systems Immunology, Max Planck Institute of Biochemistry, Martinsried, Germany.

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http://dx.doi.org/10.1038/s41592-018-0037-8DOI Listing
July 2018

BoxCar acquisition method enables single-shot proteomics at a depth of 10,000 proteins in 100 minutes.

Nat Methods 2018 06 7;15(6):440-448. Epub 2018 May 7.

Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.

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http://www.nature.com/articles/s41592-018-0003-5
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http://dx.doi.org/10.1038/s41592-018-0003-5DOI Listing
June 2018

In-depth proteomic analyses of (greenlip abalone) nacre and prismatic organic shell matrix.

Proteome Sci 2018 15;16:11. Epub 2018 Jun 15.

2Department of Geobiology, Georg-August University of Göttingen, Goldschmidstr. 3, 37077 Göttingen, Germany.

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http://dx.doi.org/10.1186/s12953-018-0139-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003135PMC
June 2018

Dimethyl-Labeling-Based Quantification of the Lysine Acetylome and Proteome of Plants.

Methods Mol Biol 2017 ;1653:65-81

Plant Proteomics, Max-Planck Institute for Plant Breeding Research, Carl-von-Linné Weg 10, 50829, Köln, Germany.

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http://dx.doi.org/10.1007/978-1-4939-7225-8_5DOI Listing
April 2018

A Primer on Concepts and Applications of Proteomics in Neuroscience.

Neuron 2017 Nov;96(3):558-571

Max-Planck-Institute of Biochemistry, Department of Proteomics and Signal Transduction, 82152 Martinsried, Germany; The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2017.09.025DOI Listing
November 2017

Region and cell-type resolved quantitative proteomic map of the human heart.

Nat Commun 2017 11 13;8(1):1469. Epub 2017 Nov 13.

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, 82152, Germany.

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http://dx.doi.org/10.1038/s41467-017-01747-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5684139PMC
November 2017

Spatiotemporal Proteomic Profiling of Huntington's Disease Inclusions Reveals Widespread Loss of Protein Function.

Cell Rep 2017 Nov;21(8):2291-2303

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82152 Martinsried, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.10.097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5714591PMC
November 2017

Why is it so difficult to measure glucagon-like peptide-1 in a mouse?

Diabetologia 2017 10 1;60(10):2066-2075. Epub 2017 Jul 1.

Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.

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http://dx.doi.org/10.1007/s00125-017-4347-7DOI Listing
October 2017

Revisiting biomarker discovery by plasma proteomics.

Mol Syst Biol 2017 09 26;13(9):942. Epub 2017 Sep 26.

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615924PMC
http://dx.doi.org/10.15252/msb.20156297DOI Listing
September 2017

Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging.

Cell Rep 2017 06;19(11):2396-2409

Max-Planck-Institute of Biochemistry, Martinsried 82152, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.05.054DOI Listing
June 2017

Social network architecture of human immune cells unveiled by quantitative proteomics.

Nat Immunol 2017 05 6;18(5):583-593. Epub 2017 Mar 6.

Experimental Systems Immunology, Max Planck Institute of Biochemistry, Bayern, Germany.

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http://dx.doi.org/10.1038/ni.3693DOI Listing
May 2017

Loss-less Nano-fractionator for High Sensitivity, High Coverage Proteomics.

Mol Cell Proteomics 2017 04 26;16(4):694-705. Epub 2017 Jan 26.

From the ‡Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany;

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http://dx.doi.org/10.1074/mcp.O116.065136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383787PMC
April 2017

Lysine acetylation in mitochondria: From inventory to function.

Mitochondrion 2017 Mar 28;33:58-71. Epub 2016 Jul 28.

Plant Proteomics, Max Planck Institute for Plant Breeding Research, Carl von Linné Weg 10, DE-50829 Cologne, Germany; Plant Physiology, Institute of Plant Biology and Biotechnology, University of Muenster, Schlossplatz 7, DE-48149 Muenster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2016.07.012DOI Listing
March 2017

CRL2 promotes unloading of the vertebrate replisome from chromatin during replication termination.

Genes Dev 2017 02 24;31(3):275-290. Epub 2017 Feb 24.

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://genesdev.cshlp.org/lookup/doi/10.1101/gad.291799.116
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http://dx.doi.org/10.1101/gad.291799.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5358724PMC
February 2017

Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology.

Cell Metab 2017 01 3;25(1):118-127. Epub 2016 Nov 3.

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried 82152, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.10.004DOI Listing
January 2017

C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons.

Nat Neurosci 2016 12 10;19(12):1610-1618. Epub 2016 Oct 10.

Institute of Clinical Neurobiology, University Hospital of Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1038/nn.4407DOI Listing
December 2016

SCAI promotes DNA double-strand break repair in distinct chromosomal contexts.

Nat Cell Biol 2016 Dec 7;18(12):1357-1366. Epub 2016 Nov 7.

Ubiquitin Signaling Group, Protein Signaling Program, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, DK-2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1038/ncb3436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278951PMC
December 2016

Proteomics reveals the effects of sustained weight loss on the human plasma proteome.

Mol Syst Biol 2016 Dec 22;12(12):901. Epub 2016 Dec 22.

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199119PMC
http://dx.doi.org/10.15252/msb.20167357DOI Listing
December 2016

Origins of mass spectrometry-based proteomics.

Authors:
Matthias Mann

Nat Rev Mol Cell Biol 2016 11 5;17(11):678. Epub 2016 Oct 5.

Department of Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, D-82152 Martinsried (near Munich), Germany.

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http://dx.doi.org/10.1038/nrm.2016.135DOI Listing
November 2016

Activation of the ATR kinase by the RPA-binding protein ETAA1.

Nat Cell Biol 2016 Nov 10;18(11):1196-1207. Epub 2016 Oct 10.

The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen, Denmark.

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http://dx.doi.org/10.1038/ncb3422DOI Listing
November 2016

Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion.

Nat Commun 2016 11 14;7:13250. Epub 2016 Nov 14.

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried 82152, Germany.

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http://dx.doi.org/10.1038/ncomms13250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114537PMC
November 2016

Proteomics to study DNA-bound and chromatin-associated gene regulatory complexes.

Hum Mol Genet 2016 Oct 11;25(R2):R106-R114. Epub 2016 Jul 11.

Department of Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Martinsried, Germany

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http://dx.doi.org/10.1093/hmg/ddw208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036873PMC
October 2016

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.

Cell 2016 Oct 13;167(3):829-842.e13. Epub 2016 Oct 13.

Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona 6500, Switzerland; Institute of Microbiology, ETH Zurich, Zurich 8093, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.09.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5075284PMC
October 2016

The Perseus computational platform for comprehensive analysis of (prote)omics data.

Nat Methods 2016 09 27;13(9):731-40. Epub 2016 Jun 27.

Computational Systems Biochemistry, Max Planck Institute of Biochemistry, Martinsried, Germany.

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http://dx.doi.org/10.1038/nmeth.3901DOI Listing
September 2016

Soluble Oligomers of PolyQ-Expanded Huntingtin Target a Multiplicity of Key Cellular Factors.

Mol Cell 2016 09 25;63(6):951-64. Epub 2016 Aug 25.

Department of Cellular Biochemistry, Max Planck Institute of Biochemistry, Am Klopferspitz 18, 82159 Martinsried, Germany; Munich Cluster for Systems Neurology, Adolf-Butenandt-Institut, Ludwig-Maximilians-Universität München, Schillerstrasse 44, 80336 München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.07.022DOI Listing
September 2016

Mass-spectrometric exploration of proteome structure and function.

Nature 2016 09;537(7620):347-55

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1038/nature19949DOI Listing
September 2016

HCD Fragmentation of Glycated Peptides.

J Proteome Res 2016 08 28;15(8):2881-90. Epub 2016 Jul 28.

Department of Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry , Am Klopferspitz 18, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1021/acs.jproteome.6b00464DOI Listing
August 2016

p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1.

Proc Natl Acad Sci U S A 2016 08 12;113(35):E5192-201. Epub 2016 Aug 12.

Max-von-Pettenkofer Institute, Ludwig-Maximilians-University Munich and German Center for Infection Research (DZIF), partner site Munich, 80336 Munich, Germany;

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http://dx.doi.org/10.1073/pnas.1603435113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024628PMC
August 2016

A Proteomics Approach to the Protein Normalization Problem: Selection of Unvarying Proteins for MS-Based Proteomics and Western Blotting.

J Proteome Res 2016 07 23;15(7):2321-6. Epub 2016 Jun 23.

Biochemical Proteomics Group, ‡Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry , 82152 Martinsried, Germany.

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http://dx.doi.org/10.1021/acs.jproteome.6b00403DOI Listing
July 2016

PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins.

J Biol Chem 2016 May 4;291(21):11016-29. Epub 2016 Apr 4.

From the Department of Cell Biology and Institute for Genetics and Genomics in Geneva (iGE3), University of Geneva, 1211-4 Geneva, Switzerland,

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http://dx.doi.org/10.1074/jbc.M115.712935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4900252PMC
May 2016

MicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Embryonic Stem Cells.

Stem Cell Reports 2016 05 14;6(5):635-642. Epub 2016 Apr 14.

Lymphocyte Development Group, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK; Epigenetics Section, MRC Clinical Sciences Centre, Faculty of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2016.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939759PMC
May 2016

Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC.

Genes Dev 2016 05;30(9):1116-27

Laboratory of Chromatin Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany;

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http://dx.doi.org/10.1101/gad.279141.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863741PMC
May 2016

Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma.

EBioMedicine 2016 May 31;7:112-20. Epub 2016 Mar 31.

Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.ebiom.2016.03.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909640PMC
May 2016

Ultra-deep and quantitative saliva proteome reveals dynamics of the oral microbiome.

Genome Med 2016 Apr 21;8(1):44. Epub 2016 Apr 21.

Department of Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, Am Klopferspitz 18, D-82152, Martinsried, Germany.

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http://dx.doi.org/10.1186/s13073-016-0293-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841045PMC
April 2016

Deep Proteomics of Breast Cancer Cells Reveals that Metformin Rewires Signaling Networks Away from a Pro-growth State.

Cell Syst 2016 03 3;2(3):159-71. Epub 2016 Mar 3.

Department of Biology, University of Rome Tor Vergata, 00133 Rome, Italy; Istituto Ricovero e Cura a Carattere Scientifico, Fondazione Santa Lucia, Rome, Italy. Electronic address:

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http://www.cell.com/cell-systems/pdf/S2405-4712(16)30035-7.p
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http://dx.doi.org/10.1016/j.cels.2016.02.005DOI Listing
March 2016

Plasma Proteome Profiling to Assess Human Health and Disease.

Cell Syst 2016 03 23;2(3):185-95. Epub 2016 Mar 23.

Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany; NNF Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, 2200 Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2016.02.015DOI Listing
March 2016

Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells.

Cell Syst 2015 Aug 26;1(2):141-51. Epub 2015 Aug 26.

Medical Systems Biology, UCC, Medical Faculty Carl Gustav Carus, TU Dresden, 01307 Dresden, Germany; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2015.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023010PMC
August 2015