Publications by authors named "Matthias Kloor"

100Publications

Does Side Really Matter? Survival Analysis among Patients with Right- Versus Left-Sided Colon Cancer: A Propensity Score-Adjusted Analysis.

Ann Surg Oncol 2020 Sep 21. Epub 2020 Sep 21.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1245/s10434-020-09116-yDOI Listing
September 2020

Response to neoadjuvant treatment among rectal cancer patients in a population-based cohort.

Int J Colorectal Dis 2020 Sep 19. Epub 2020 Sep 19.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00384-020-03744-2DOI Listing
September 2020

Age-dependent performance of BRAF mutation testing in Lynch syndrome diagnostics.

Int J Cancer 2020 Nov 14;147(10):2801-2810. Epub 2020 Sep 14.

Department of Applied Tumor Biology, University Hospital Heidelberg, Cooperation Unit Applied Tumor Biology, German Cancer research Center (DKFZ), and Molecular Medicine Partnership Unit (MMPU), University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.33273DOI Listing
November 2020

Colonoscopy and Reduction of Colorectal Cancer Risk by Molecular Tumor Subtypes: A Population-Based Case-Control Study.

Am J Gastroenterol 2020 Aug 27. Epub 2020 Aug 27.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.14309/ajg.0000000000000819DOI Listing
August 2020

A Frameshift Peptide Neoantigen-Based Vaccine for Mismatch Repair-Deficient Cancers: A Phase I/IIa Clinical Trial.

Clin Cancer Res 2020 Sep 15;26(17):4503-4510. Epub 2020 Jun 15.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-3517DOI Listing
September 2020

Implications of Hereditary Origin on the Immune Phenotype of Mismatch Repair-Deficient Cancers: Systematic Literature Review.

J Clin Med 2020 Jun 4;9(6). Epub 2020 Jun 4.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.3390/jcm9061741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7357024PMC
June 2020

Smoking, alcohol consumption and colorectal cancer risk by molecular pathological subtypes and pathways.

Br J Cancer 2020 May 30;122(11):1604-1610. Epub 2020 Mar 30.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41416-020-0803-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250912PMC
May 2020

Resistance of the stable-towards more precise prediction of response to immune checkpoint blockade in microsatellite-unstable cancer patients.

Authors:
Matthias Kloor

Ann Transl Med 2019 Nov;7(21):603

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.21037/atm.2019.10.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011599PMC
November 2019

Postmenopausal hormone replacement therapy and colorectal cancer risk by molecular subtypes and pathways.

Int J Cancer 2020 Aug 30;147(4):1018-1026. Epub 2020 Jan 30.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.32868DOI Listing
August 2020

Association of BMI and major molecular pathological markers of colorectal cancer in men and women.

Am J Clin Nutr 2020 03;111(3):562-569

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1093/ajcn/nqz315DOI Listing
March 2020

E3 ubiquitin ligase Smurf2: a prognostic factor in microsatellite stable colorectal cancer.

Cancer Manag Res 2019 22;11:1795-1803. Epub 2019 Feb 22.

Department of General, Visceral and Transplantation Surgery, University of Heidelberg, Heidelberg 69120, Germany,

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http://dx.doi.org/10.2147/CMAR.S178111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391146PMC
February 2019

Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report.

Hered Cancer Clin Pract 2019 28;17. Epub 2019 Feb 28.

4Department of Tumor Biology, Institute of Cancer Research, The Norwegian Radium Hospital, part of Oslo University Hospital, Olso, Norway.

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https://hccpjournal.biomedcentral.com/articles/10.1186/s1305
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http://dx.doi.org/10.1186/s13053-019-0106-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394091PMC
February 2019

Hematological Malignancies in Adults With a Family Predisposition.

Dtsch Arztebl Int 2018 12;115(50):848-854

Department of Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital and Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ) Heidelberg, Germany; Department of Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany; Medical Oncology, National Center for Tumor Diseases (NCT), Heidelberg University Hospital, Heidelberg, Germany; Section Head of Translational Gynecology, University Women's Hospital Heidelberg, German Cancer Consortium (DKTK), Heidelberg, Germany; Institute of Pathology, Department of Applied Tumor Biology, Heidelberg University Hospital, Heidelberg, Germany.

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https://www.aerzteblatt.de/10.3238/arztebl.2018.0848
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http://dx.doi.org/10.3238/arztebl.2018.0848DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375069PMC
December 2018

Association of Aspirin and Nonsteroidal Anti-Inflammatory Drugs With Colorectal Cancer Risk by Molecular Subtypes.

J Natl Cancer Inst 2019 05;111(5):475-483

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1093/jnci/djy170DOI Listing
May 2019

Complex pattern of immune evasion in MSI colorectal cancer.

Oncoimmunology 2018 26;7(7):e1445453. Epub 2018 Mar 26.

Department of Applied Tumour Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1080/2162402X.2018.1445453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993484PMC
March 2018

The Association Between Mutations in BRAF and Colorectal Cancer-Specific Survival Depends on Microsatellite Status and Tumor Stage.

Clin Gastroenterol Hepatol 2019 02 13;17(3):455-462.e6. Epub 2018 Apr 13.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.cgh.2018.04.015DOI Listing
February 2019

Three molecular pathways model colorectal carcinogenesis in Lynch syndrome.

Int J Cancer 2018 07 23;143(1):139-150. Epub 2018 Feb 23.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.31300DOI Listing
July 2018

High numbers of PDCD1 (PD-1)-positive T cells and mutations in microsatellite-unstable colorectal cancer.

Oncoimmunology 2018 6;7(2):e1390640. Epub 2017 Nov 6.

Department of Applied Tumour Biology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Heidelberg, Germany, and Molecular Medicine Partnership Unit (MMPU), Heidelberg University Hospital and EMBL Heidelberg.

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http://dx.doi.org/10.1080/2162402X.2017.1390640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5749658PMC
November 2017

Associations Between Molecular Classifications of Colorectal Cancer and Patient Survival: A Systematic Review.

Clin Gastroenterol Hepatol 2019 02 3;17(3):402-410.e2. Epub 2018 Jan 3.

Division of Clinical Epidemiology and Aging Research, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2017.12.038DOI Listing
February 2019

Analyzing epigenetic control of galectin expression indicates silencing of galectin-12 by promoter methylation in colorectal cancer.

IUBMB Life 2017 12 3;69(12):962-970. Epub 2017 Nov 3.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Germany.

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http://dx.doi.org/10.1002/iub.1690DOI Listing
December 2017

Associations of red and processed meat intake with major molecular pathological features of colorectal cancer.

Eur J Epidemiol 2017 05 23;32(5):409-418. Epub 2017 Jun 23.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s10654-017-0275-6DOI Listing
May 2017

The association between microsatellite instability and lymph node count in colorectal cancer.

Virchows Arch 2017 Jul 23;471(1):57-64. Epub 2017 May 23.

Institute of Pathology, Charité University Medicine, Virchoweg 15 / Charitéplatz 1, 10117, Berlin, Germany.

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http://dx.doi.org/10.1007/s00428-017-2150-yDOI Listing
July 2017

HLA class II antigen-processing pathway in tumors: Molecular defects and clinical relevance.

Oncoimmunology 2017 6;6(2):e1171447. Epub 2017 Feb 6.

Departments of Surgery and Orthopedic Surgery, Massachusetts General Hospital, Harvard Medical School , Boston, MA, USA.

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http://dx.doi.org/10.1080/2162402X.2016.1171447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5353941PMC
February 2017

Double germline mutations in APC and BRCA2 in an individual with a pancreatic tumor.

Fam Cancer 2017 04;16(2):303-309

Institute of Human Genetics, Heidelberg University, Im Neuenheimer Feld 440, 69120, Heidelberg, Germany.

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http://link.springer.com/10.1007/s10689-016-9952-y
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http://dx.doi.org/10.1007/s10689-016-9952-yDOI Listing
April 2017

No association of CpG island methylator phenotype and colorectal cancer survival: population-based study.

Br J Cancer 2016 Nov 3;115(11):1359-1366. Epub 2016 Nov 3.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1038/bjc.2016.361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129826PMC
November 2016

Low density of FOXP3-positive T cells in normal colonic mucosa is related to the presence of beta2-microglobulin mutations in Lynch syndrome-associated colorectal cancer.

Oncoimmunology 2016 Feb 11;5(2):e1075692. Epub 2015 Nov 11.

Department of Applied Tumour Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Im Neuenheimer Feld 280, Heidelberg, Germany, and Molecular Medicine Partnership Unit, University Hospital Heidelberg and EMBL Heidelberg , Germany.

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http://dx.doi.org/10.1080/2162402X.2015.1075692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801455PMC
February 2016

CTNNB1-mutant colorectal carcinomas with immediate invasive growth: a model of interval cancers in Lynch syndrome.

Fam Cancer 2016 10;15(4):579-86

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s10689-016-9899-zDOI Listing
October 2016

The Immune Biology of Microsatellite-Unstable Cancer.

Trends Cancer 2016 03 5;2(3):121-133. Epub 2016 Mar 5.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Clinical Cooperation Unit (CCU 105) of the German Cancer Research Center and Molecular Medicine Partner Unit (MMPU) of the European Molecular Biology Laboratory, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.trecan.2016.02.004DOI Listing
March 2016

Genetic heterogeneity in synchronous colorectal cancers impacts genotyping approaches and therapeutic strategies.

Genes Chromosomes Cancer 2016 Mar 9;55(3):268-77. Epub 2015 Dec 9.

Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/gcc.22330DOI Listing
March 2016

Microsatellite instability in pulmonary adenocarcinomas: a comprehensive study of 480 cases.

Virchows Arch 2016 Mar 4;468(3):313-9. Epub 2015 Dec 4.

Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00428-015-1892-7DOI Listing
March 2016

Overexpression of SIX1 is an independent prognostic marker in stage I-III colorectal cancer.

Int J Cancer 2015 Nov 21;137(9):2104-13. Epub 2015 May 21.

Department of Gastrointestinal, Thoracic and Vascular Surgery, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1002/ijc.29596DOI Listing
November 2015

Dose-dependent effect of 2-deoxy-D-glucose on glycoprotein mannosylation in cancer cells.

IUBMB Life 2015 Mar 9;67(3):218-26. Epub 2015 Apr 9.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany; Clinical Cooperation Unit Applied Tumor Biology, DKFZ (German Cancer Research Center) Heidelberg, Heidelberg, Germany; Molecular Medicine Partnership Unit, University of Heidelberg and European Molecular Biology Laboratory, Heidelberg, Germany.

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http://dx.doi.org/10.1002/iub.1364DOI Listing
March 2015

Mismatch repair-deficient crypt foci in Lynch syndrome--molecular alterations and association with clinical parameters.

PLoS One 2015 27;10(3):e0121980. Epub 2015 Mar 27.

Department of Applied Tumour Biology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, 69120 Heidelberg, Germany, and Clinical Cooperation Unit Applied Tumour Biology, DKFZ (German Cancer Research Center) Heidelberg, Im Neuenheimer Feld 280, Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121980PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376900PMC
March 2016

Distinctive Spatiotemporal Stability of Somatic Mutations in Metastasized Microsatellite-stable Colorectal Cancer.

Am J Surg Pathol 2015 Aug;39(8):1140-7

Departments of *General Pathology †Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg ‡Clinical Cooperation Unit Applied Tumor Biology, DKFZ ∥National Center for Tumor Diseases (NCT), Heidelberg §Institute of Pathology, Charité University Medicine, Berlin, Germany.

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http://dx.doi.org/10.1097/PAS.0000000000000423DOI Listing
August 2015

Statin use and survival after colorectal cancer: the importance of comprehensive confounder adjustment.

J Natl Cancer Inst 2015 Jun 13;107(6):djv045. Epub 2015 Mar 13.

Division of Clinical Epidemiology and Aging Research (MH, LJ, HBr), Division of Cancer Epidemiology (AR, JCC), and Unit of Molecular Tumor Pathology (WR), German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Pathology (CT, WR) and Department of Applied Tumor Biology (MK), Institute of Pathology, Heidelberg University Hospital, Germany; Institute of Pathology, Charité University Medicine, Berlin, Germany (HBl); German Cancer Consortium (DKTK), Heidelberg, Germany (HBr).

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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/djv045DOI Listing
June 2015

Association of high CD4-positive T cell infiltration with mutations in HLA class II-regulatory genes in microsatellite-unstable colorectal cancer.

Cancer Immunol Immunother 2015 Mar 2;64(3):357-66. Epub 2014 Dec 2.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00262-014-1638-4DOI Listing
March 2015

Potential of fecal microbiota for early-stage detection of colorectal cancer.

Mol Syst Biol 2014 Nov 28;10:766. Epub 2014 Nov 28.

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany Molecular Medicine Partnership Unit (MMPU), University Hospital Heidelberg and European Molecular Biology Laboratory, Heidelberg, Germany Max Delbrück Centre for Molecular Medicine, Berlin, Germany

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4299606PMC
http://dx.doi.org/10.15252/msb.20145645DOI Listing
November 2014

Genetic evolution of T-cell resistance in the course of melanoma progression.

Clin Cancer Res 2014 Dec 7;20(24):6593-604. Epub 2014 Oct 7.

Department of Dermatology, University Hospital Essen, University Duisburg-Essen, Essen, Germany. German Cancer Consortium (DKTK), Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-0567DOI Listing
December 2014

No evidence of oncogenic KRAS mutations in squamous cell carcinomas of the anogenital tract and head and neck region independent of human papillomavirus and p16(INK4a) status.

Hum Pathol 2014 Nov 23;45(11):2347-54. Epub 2014 Aug 23.

Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, and Clinical Cooperation Unit Applied Tumor Biology, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2014.08.001DOI Listing
November 2014

Lymph node count and prognosis in colorectal cancer: the influence of examination quality.

Int J Cancer 2015 Apr 24;136(8):1957-66. Epub 2014 Sep 24.

Department of General Pathology, Institute of Pathology, Charite University Medicine Hospital, Charitéplatz 1, Berlin, Germany.

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http://dx.doi.org/10.1002/ijc.29221DOI Listing
April 2015

Detection of coding microsatellite frameshift mutations in DNA mismatch repair-deficient mouse intestinal tumors.

Mol Carcinog 2015 Nov 11;54(11):1376-86. Epub 2014 Sep 11.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/mc.22213DOI Listing
November 2015

A multiplex method for the detection of serum antibodies against in silico-predicted tumor antigens.

Cancer Immunol Immunother 2014 Dec 21;63(12):1251-9. Epub 2014 Aug 21.

Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 224, 69120, Heidelberg, Germany,

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http://dx.doi.org/10.1007/s00262-014-1595-yDOI Listing
December 2014

Lack of Absent in Melanoma 2 (AIM2) expression in tumor cells is closely associated with poor survival in colorectal cancer patients.

Int J Cancer 2014 Nov 28;135(10):2387-96. Epub 2014 Apr 28.

Department of Vascular and Endovascular Surgery, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.28891DOI Listing
November 2014

Immune escape and survival mechanisms in circulating tumor cells of colorectal cancer.

Cancer Res 2014 Mar 5;74(6):1694-704. Epub 2014 Mar 5.

Authors' Affiliations: Department of General, Gastrointestinal and Transplant Surgery; Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg; German Cancer Research Center, Division of Biostatistics, Heidelberg; Department of Gastrointestinal, Thoracic and Vascular Surgery, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Department of General, Visceral and Paediatric Surgery, Medical Faculty, University Hospital, Heinrich Heine University, Düsseldorf, Germany; and Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1885DOI Listing
March 2014

Colorectal cancer.

Lancet 2014 Apr 11;383(9927):1490-1502. Epub 2013 Nov 11.

Department of Medicine, Ruhr University, Bochum, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736136164
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http://dx.doi.org/10.1016/S0140-6736(13)61649-9DOI Listing
April 2014

Body mass index and microsatellite instability in colorectal cancer: a population-based study.

Cancer Epidemiol Biomarkers Prev 2013 Dec 14;22(12):2303-11. Epub 2013 Oct 14.

Authors' Affiliations: Division of Clinical Epidemiology and Aging Research; Unit of Genetic Epidemiology, German Cancer Research Center (DKFZ); Department of Pathology, Institute of Pathology; Department of Applied Tumor Biology, Institute of Pathology, Heidelberg University Hospital; National Center for Tumor Diseases (NCT) Tissue Bank, Heidelberg; and Institute of Pathology, Charité University Medicine, Berlin, Germany.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0239DOI Listing
December 2013

Clinical significance of microsatellite instability in colorectal cancer.

Langenbecks Arch Surg 2014 Jan 19;399(1):23-31. Epub 2013 Sep 19.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany,

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http://dx.doi.org/10.1007/s00423-013-1112-3DOI Listing
January 2014

Towards a vaccine to prevent cancer in Lynch syndrome patients.

Fam Cancer 2013 Jun;12(2):307-12

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 224, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s10689-013-9662-7DOI Listing
June 2013

BRAF V600E-specific immunohistochemistry for the exclusion of Lynch syndrome in MSI-H colorectal cancer.

Int J Cancer 2013 Oct 25;133(7):1624-30. Epub 2013 Apr 25.

Department of Neuropathology, Institute of Pathology, University Hospital Heidelberg and Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.28183DOI Listing
October 2013

T cell responses against microsatellite instability-induced frameshift peptides and influence of regulatory T cells in colorectal cancer.

Cancer Immunol Immunother 2013 Jan 23;62(1):27-37. Epub 2012 Jun 23.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 220, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00262-012-1303-8DOI Listing
January 2013

Hepatoblastoma in two siblings and familial adenomatous polyposis: causal nexus or coincidence?

Fam Cancer 2012 Sep;11(3):529-33

Institute of Human Genetics, Heidelberg University, Im Neuenheimer Feld 366, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s10689-012-9538-2DOI Listing
September 2012

Colonic carcinogenesis along different genetic routes: glycophenotyping of tumor cases separated by microsatellite instability/stability.

Histochem Cell Biol 2012 Aug 8;138(2):339-50. Epub 2012 May 8.

Abteilung Angewandte Tumorbiologie, Universitaetsklinikum Heidelberg, Im Neuenheimer Feld 220/221, 69120 Heidelberg, Germany.

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http://link.springer.com/10.1007/s00418-012-0957-9
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http://dx.doi.org/10.1007/s00418-012-0957-9DOI Listing
August 2012

Prevalence of mismatch repair-deficient crypt foci in Lynch syndrome: a pathological study.

Lancet Oncol 2012 Jun 1;13(6):598-606. Epub 2012 May 1.

Department of Applied Tumour Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1016/S1470-2045(12)70109-2DOI Listing
June 2012

The molecular basis of EPCAM expression loss in Lynch syndrome-associated tumors.

Mod Pathol 2012 Jun 2;25(6):911-6. Epub 2012 Mar 2.

Department of Applied Tumor Biology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/modpathol.2012.30DOI Listing
June 2012

Lynch syndrome: clinical, pathological, and genetic insights.

Langenbecks Arch Surg 2012 Apr 24;397(4):513-25. Epub 2012 Feb 24.

Department of Visceral, Thoracic and Vascular Surgery, Philipps University, Marburg, Germany.

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http://dx.doi.org/10.1007/s00423-012-0918-8DOI Listing
April 2012

Brush border myosin Ia has tumor suppressor activity in the intestine.

Proc Natl Acad Sci U S A 2012 Jan 18;109(5):1530-5. Epub 2012 Jan 18.

Group of Molecular Oncology, and Group of Drug Delivery and Targeting, Centro de Investigaciones en Bioquímica y Biología Molecular-Nanomedicine, Vall d'Hebron University Hospital Research Institute, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.

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http://dx.doi.org/10.1073/pnas.1108411109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277176PMC
January 2012

Biallelic MLH1 SNP cDNA expression or constitutional promoter methylation can hide genomic rearrangements causing Lynch syndrome.

J Med Genet 2011 Aug 28;48(8):513-9. Epub 2011 Jun 28.

Medical Department, Campus Innenstadt, Klinikum der Universität, Munich, Germany; MGZ-Center of Medical Genetics, Munich, Germany.

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http://dx.doi.org/10.1136/jmedgenet-2011-100050DOI Listing
August 2011

Dendritic cell and macrophage infiltration in microsatellite-unstable and microsatellite-stable colorectal cancer.

Fam Cancer 2011 Sep;10(3):557-65

Department of Applied Tumour Biology, Institute of Pathology, University Hospital Heidelberg, Im Neuenheimer Feld 220, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s10689-011-9449-7DOI Listing
September 2011