Publications by authors named "Matthias Farlik"

31Publications

Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets.

Genome Biol 2020 05 6;21(1):106. Epub 2020 May 6.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH BT 25.3, 1090, Vienna, Austria.

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http://dx.doi.org/10.1186/s13059-020-02006-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201533PMC
May 2020

NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity.

J Immunol 2019 03 4;202(6):1724-1734. Epub 2019 Feb 4.

Department of Biomedical Science, Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, 1210 Vienna, Austria;

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http://dx.doi.org/10.4049/jimmunol.1701649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398083PMC
March 2019

Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency.

Cell Stem Cell 2019 01 21;24(1):123-137.e8. Epub 2018 Nov 21.

Department of Molecular Biology, Faculty of Science, Radboud University, Radboud Institute for Molecular Life Sciences (RIMLS), 6525GA Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.10.017DOI Listing
January 2019

An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion.

Cell Stem Cell 2018 Jun 24;22(6):879-892.e6. Epub 2018 May 24.

Department of Microbiology, Immunobiology and Genetics, Center for Molecular Biology of the University of Vienna, Max F. Perutz Laboratories, Vienna Biocenter (VBC), 1030 Vienna, Austria. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19345909183022
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http://dx.doi.org/10.1016/j.stem.2018.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988582PMC
June 2018

It is a differentiation game: STAT5 in a new role.

Cell Death Differ 2017 06 12;24(6):953-954. Epub 2017 May 12.

Department for Biomedical Sciences, Institute of Pharmacology and Toxicology, University of Veterinary Medicine, Vienna, Austria.

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http://dx.doi.org/10.1038/cdd.2017.71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442481PMC
June 2017

DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation.

Cell Stem Cell 2016 12 17;19(6):808-822. Epub 2016 Nov 17.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria; Max Planck Institute for Informatics, Saarland Informatics Campus, 66123 Saarbrücken, Germany; Department of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.10.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145815PMC
December 2016

Multi-Omics of Single Cells: Strategies and Applications.

Trends Biotechnol 2016 08 20;34(8):605-608. Epub 2016 May 20.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.

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http://dx.doi.org/10.1016/j.tibtech.2016.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959511PMC
August 2016

Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.

EMBO Rep 2016 Feb 21;17(2):178-87. Epub 2015 Dec 21.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria Christian Doppler Laboratory for Chemical Epigenetics and Antiinfectives, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

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http://dx.doi.org/10.15252/embr.201540946DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784001PMC
February 2016

Differential DNA Methylation Analysis without a Reference Genome.

Cell Rep 2015 Dec 8;13(11):2621-2633. Epub 2015 Dec 8.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria; Department of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria; Max Planck Institute for Informatics, 66123 Saarbrücken, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.11.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695333PMC
December 2015

Imprinted expression in cystic embryoid bodies shows an embryonic and not an extra-embryonic pattern.

Dev Biol 2015 Jun 24;402(2):291-305. Epub 2015 Apr 24.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Lazarettgasse 14, AKH-BT25.3, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2015.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454777PMC
June 2015

Single-cell DNA methylome sequencing and bioinformatic inference of epigenomic cell-state dynamics.

Cell Rep 2015 Mar 26;10(8):1386-97. Epub 2015 Feb 26.

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090 Vienna, Austria; Department of Laboratory Medicine, Medical University of Vienna, 1090 Vienna, Austria; Max Planck Institute for Informatics, 66123 Saarbrücken, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542311PMC
March 2015

Contribution of a TANK-binding kinase 1-interferon (IFN) regulatory factor 7 pathway to IFN-γ-induced gene expression.

Mol Cell Biol 2012 Mar 17;32(6):1032-43. Epub 2012 Jan 17.

Max F. Perutz Laboratories, Department of Genetics, Microbiology and Immunobiology, University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1128/MCB.06021-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295005PMC
March 2012

Nonconventional initiation complex assembly by STAT and NF-kappaB transcription factors regulates nitric oxide synthase expression.

Immunity 2010 Jul;33(1):25-34

Max F. Perutz Laboratories, Department of Genetics, Microbiology and Immunobiology, University of Vienna, Dr. Bohr-Gasse 9/4, A1030 Vienna, Austria.

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http://dx.doi.org/10.1016/j.immuni.2010.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2914224PMC
July 2010

Distinct modes of action applied by transcription factors STAT1 and IRF1 to initiate transcription of the IFN-gamma-inducible gbp2 gene.

Proc Natl Acad Sci U S A 2007 Feb 9;104(8):2849-54. Epub 2007 Feb 9.

Max F. Perutz Laboratories, Department of Microbiology and Immunobiology, University of Vienna, A1030 Vienna, Austria.

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http://dx.doi.org/10.1073/pnas.0610944104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1815270PMC
February 2007