Matthias Eikermann

Matthias Eikermann

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Matthias Eikermann

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Effects of High Neuromuscular Blocking Agent Dose on Postoperative Respiratory Complications in Infants and Children.

Acta Anaesthesiol Scand 2019 Sep 17. Epub 2019 Sep 17.

Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.

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http://dx.doi.org/10.1111/aas.13478DOI Listing
September 2019

BOSTN Bundle Intervention for Perioperative Screening and Management of Patients With Suspected Obstructive Sleep Apnea: A Hospital Registry Study.

Anesth Analg 2019 Jul 2. Epub 2019 Jul 2.

From the Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000004294DOI Listing
July 2019

Global and Regional Respiratory Mechanics During Robotic-Assisted Laparoscopic Surgery: A Randomized Study.

Anesth Analg 2019 Jul 26. Epub 2019 Jul 26.

From the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000004289DOI Listing
July 2019

The Effects of Postoperative Residual Neuromuscular Blockade on Hospital Costs and Intensive Care Unit Admission: A Population-Based Cohort Study.

Anesth Analg 2019 Jun;128(6):1129-1136

Department of Anesthesia, Critical Care, and Pain Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000004028DOI Listing
June 2019

Contact-free respiratory monitoring using bed wheel sensors: a valid respiratory monitoring technique with significant potential impact on public health.

J Appl Physiol (1985) 2019 May 28;126(5):1430-1431. Epub 2019 Mar 28.

Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, Massachusetts.

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http://dx.doi.org/10.1152/japplphysiol.00198.2019DOI Listing
May 2019

Patent foramen ovale and long-term risk of ischaemic stroke after surgery.

Eur Heart J 2019 Mar;40(11):914-924

Department of Anaesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Centre, Harvard Medical School, 330 Brookline Avenue, Boston, MA, USA.

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http://dx.doi.org/10.1093/eurheartj/ehy402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416532PMC
March 2019

Does reversal of neuromuscular block with sugammadex reduce readmission rate after surgery?

Br J Anaesth 2019 03 23;122(3):294-298. Epub 2019 Jan 23.

Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bja.2018.12.015DOI Listing
March 2019

Effects of Anticholinesterase Reversal Under General Anesthesia on Postoperative Cardiovascular Complications: A Retrospective Cohort Study.

Anesth Analg 2019 Mar 14. Epub 2019 Mar 14.

From the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000004099DOI Listing
March 2019

The association between migraine and hospital readmission due to pain after surgery: A hospital registry study.

Cephalalgia 2019 Feb 8;39(2):286-295. Epub 2018 Jul 8.

1 Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1177/0333102418786457DOI Listing
February 2019

Influence of the initial level of consciousness on early, goal-directed mobilization: a post hoc analysis.

Intensive Care Med 2019 02 21;45(2):201-210. Epub 2019 Jan 21.

Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Ave, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s00134-019-05528-xDOI Listing
February 2019

Recent advances in understanding and managing postoperative respiratory problems.

F1000Res 2019 18;8. Epub 2019 Feb 18.

Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

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http://dx.doi.org/10.12688/f1000research.16687.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381803PMC
February 2019

Response: "Intraoperative Fluid Resuscitation: Importance of Individualized Treatment".

Ann Surg 2018 12;268(6):e43-e44

Massachusetts General Hospital, Department of Anesthesia, Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA Beth Israel Deaconess Medical Center, Department of Anesthesia and Critical Care, and Pain Medicine, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/SLA.0000000000002497DOI Listing
December 2018

Comparison of a novel clinical score to estimate the risk of REsidual neuromuscular block Prediction Score and the last train-of-four count documented in the electronic anaesthesia record: A retrospective cohort study of electronic data on file.

Eur J Anaesthesiol 2018 11;35(11):883-892

From the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital (MIR, PYN, HD, FTS, SDG, TTH), Harvard Medical School, Boston, Massachusetts (MIR, PYN, HD, FTS, SDG, TTH, ME), Department of Adult Intensive Care, Queen Mary Hospital and The University of Hong Kong, Pok Fu Lam, Hong Kong (PYN), Department of Anesthesiology, Vanderbilt University School of Medicine, Nashville, Tennessee (JPW), Department of Anesthesia, Critical Care, and Pain Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA (ME) and Universitätsklinikum Essen, Essen, Germany (ME).

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http://Insights.ovid.com/crossref?an=00003643-900000000-9854
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http://dx.doi.org/10.1097/EJA.0000000000000861DOI Listing
November 2018

Opioid Use Disorders and the Risk of Postoperative Pulmonary Complications.

Anesth Analg 2018 09;127(3):767-774

Department of Anesthesia and Pain Medicine, Toronto General Hospital and University of Toronto, Toronto, Canada.

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http://Insights.ovid.com/crossref?an=00000539-201809000-0002
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http://dx.doi.org/10.1213/ANE.0000000000003307DOI Listing
September 2018

Supplemental Carbon Dioxide Stabilizes the Upper Airway in Volunteers Anesthetized with Propofol.

Anesthesiology 2018 07;129(1):37-46

From the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts (K.J.R., H.D., T.H.) Department of Anesthesiology, Herlev and Gentofte Hospital, Herlev, Denmark (J.B.S.) Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Hospital, Boston, Massachusetts (J.Patlak, M.E.) Helios Klinikum Krefeld, Klinik für Orthopädie, Unfall- und Handchirurgie, Krefeld, Germany (J.C.R.S.) Klinik für Anäesthesiologie und Intensivmedizin, Universität Duisburg Essen and Universitätsklinikum Essen, Essen, Germany (J.Peters, M.E.).

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http://dx.doi.org/10.1097/ALN.0000000000002239DOI Listing
July 2018

In response to letter: Opioids use in ICU: a causal agent for sleep apnea, unmasking the undiagnosed sleep apnea or both in the ICU.

Sleep 2018 07;41(7)

Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1093/sleep/zsy082DOI Listing
July 2018

Quantifying the effect of slice thickness, intravenous contrast and tube current on muscle segmentation: Implications for body composition analysis.

Eur Radiol 2018 Jun 9;28(6):2455-2463. Epub 2018 Jan 9.

Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA.

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http://dx.doi.org/10.1007/s00330-017-5191-3DOI Listing
June 2018

Patent Foramen Ovale and Risk of Perioperative Stroke-Reply.

JAMA 2018 06;319(24):2557-2558

Beth Israel Deaconess Medical Center, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2018.5736DOI Listing
June 2018

Lumbar skeletal muscle index derived from routine computed tomography exams predict adverse post-extubation outcomes in critically ill patients.

J Crit Care 2018 04 23;44:117-123. Epub 2017 Oct 23.

Department of Radiology, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2017.10.033DOI Listing
April 2018

Variability in the Use of Protective Mechanical Ventilation During General Anesthesia.

Anesth Analg 2018 02;126(2):503-512

From the Department of Anesthesiology, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1213/ANE.0000000000002343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696999PMC
February 2018

Prediction of long-term outcome subtypes in ARDS: first steps towards personalised medicine in critical care.

Thorax 2017 12 7;72(12):1067-1068. Epub 2017 Oct 7.

Department of Anesthesia, Critical and Pain Medicine, Beth Israel Deconness Medical Center, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/thoraxjnl-2017-210775DOI Listing
December 2017

Postoperative interruption of sedation on arrival in the surgical ICU: a new standard of care.

Lancet Respir Med 2017 10 18;5(10):764-765. Epub 2017 Sep 18.

Department of Anaesthesia, Beth Israel Deaconness Medical Center, Boston, MA 02215, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S22132600173035
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http://dx.doi.org/10.1016/S2213-2600(17)30350-8DOI Listing
October 2017

The obesity conundrum in sepsis.

BMC Anesthesiol 2017 Oct 25;17(1):147. Epub 2017 Oct 25.

Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA, USA.

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http://dx.doi.org/10.1186/s12871-017-0434-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657099PMC
October 2017

Should Neuromuscular Blocking Agents Always Be Reversed?

Anesthesiology 2017 07;127(1):194

Massachusetts General Hospital, Boston, Massachusetts (M.J.M.).

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http://dx.doi.org/10.1097/ALN.0000000000001693DOI Listing
July 2017

Prevention of respiratory complications of the surgical patient: actionable plan for continued process improvement.

Curr Opin Anaesthesiol 2017 Jun;30(3):399-408

aDepartment of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA bKlinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen, Essen, Germany.

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http://dx.doi.org/10.1097/ACO.0000000000000465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434965PMC
June 2017

Inhibition of the P2X7-PANX1 complex suppresses spreading depolarization and neuroinflammation.

Brain 2017 Jun;140(6):1643-1656

Neurovascular Research Lab, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.

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https://academic.oup.com/brain/article/140/6/1643/3744970
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http://dx.doi.org/10.1093/brain/awx085DOI Listing
June 2017

Development and validation of a Score for Preoperative Prediction of Obstructive Sleep Apnea (SPOSA) and its perioperative outcomes.

BMC Anesthesiol 2017 05 30;17(1):71. Epub 2017 May 30.

Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, 55 Fruit Street, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1186/s12871-017-0361-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450400PMC
May 2017

Anesthesia Residents Preferentially Request Operating Room Case Assignments with Complex Cases.

J Med Syst 2017 Apr 10;41(4):64. Epub 2017 Mar 10.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1007/s10916-017-0718-3DOI Listing
April 2017

In Response.

Anesth Analg 2017 04;124(4):1371-1372

Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts,

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http://dx.doi.org/10.1213/ANE.0000000000001869DOI Listing
April 2017

Proper selection of sedative drugs improves outcomes: volatile anesthetics are surgeons' best friends.

Ann Transl Med 2017 Mar;5(5):122

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA;; Klinik für Anästhesiologie und Intensivmedizin, Universitaetsklinikum Essen, Essen, Germany.

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http://dx.doi.org/10.21037/atm.2017.02.24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5360622PMC
March 2017

Early goal-directed mobilisation after surgery - Authors' reply.

Lancet 2017 02 17;389(10070):695-696. Epub 2017 Feb 17.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/S0140-6736(17)30334-3DOI Listing
February 2017

Dose-Dependent Protective Effect of Inhalational Anesthetics Against Postoperative Respiratory Complications: A Prospective Analysis of Data on File From Three Hospitals in New England.

Crit Care Med 2017 Jan;45(1):e30-e39

1Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA. 2Department of Anesthesiology, University of Copenhagen, Herlev Hospital, Herlev, Denmark. 3Institute of Public Health, Charité - Universitätsmedizin Berlin, Germany. 4Klinik für Anästhesiologie und Intensivmedizin, Universitaetsklinikum Essen, Essen, Germany.

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http://dx.doi.org/10.1097/CCM.0000000000002015DOI Listing
January 2017

Migraine and risk of perioperative ischemic stroke and hospital readmission: hospital based registry study.

BMJ 2017 Jan 10;356:i6635. Epub 2017 Jan 10.

Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225233PMC
http://dx.doi.org/10.1136/bmj.i6635DOI Listing
January 2017

Can Sarcopenia Quantified by Ultrasound of the Rectus Femoris Muscle Predict Adverse Outcome of Surgical Intensive Care Unit Patients as well as Frailty? A Prospective, Observational Cohort Study.

Ann Surg 2016 Dec;264(6):1116-1124

*Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA†Departments of Emergency Medicine and Anesthesiology, Division of Critical Care, University of California, San Diego, CA‡Departments of Surgery and Emergency Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA§Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA¶Department of Surgery, University of Michigan Medical School, Ann Arbor, MI||Inserm Research Center for Epidemiology and Biostatistics (U897)-Team Neuroepidemiology, University of Bordeaux, College of Health Sciences, Bordeaux, France**University of Bordeaux, College of Health Sciences, Bordeaux, France††Department of Anesthesia and Critical Care Medicine, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000001546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4907876PMC
December 2016

In Response.

Anesth Analg 2016 10;123(4):1060-1

Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts,

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http://dx.doi.org/10.1213/ANE.0000000000001443DOI Listing
October 2016

Early, goal-directed mobilisation in the surgical intensive care unit: a randomised controlled trial.

Lancet 2016 Oct;388(10052):1377-1388

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA; Universität Duisburg-Essen, Klinik für Anaesthesiologie und Intensivmedizin, Essen, Germany. Electronic address:

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http://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(
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http://dx.doi.org/10.1016/S0140-6736(16)31637-3DOI Listing
October 2016

Minimum Effective Doses of Succinylcholine and Rocuronium During Electroconvulsive Therapy: A Prospective, Randomized, Crossover Trial.

Anesth Analg 2016 09;123(3):587-96

From the *Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; †Broad Institute of MIT and Harvard, Cambridge, Massachusetts; ‡Department of Biomedical Informatics, Harvard Medical School, Boston, Massachusetts; §Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden University, Leiden, The Netherlands; ‖Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; ¶Patient Care Services/Special Care Nursery, Massachusetts General Hospital, Boston, Massachusetts; and #Clinic for Anesthesiology and Intensive Care, Essen University Hospital, Essen, Germany.

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http://dx.doi.org/10.1213/ANE.0000000000001218DOI Listing
September 2016

Effects of Depth of Propofol and Sevoflurane Anesthesia on Upper Airway Collapsibility, Respiratory Genioglossus Activation, and Breathing in Healthy Volunteers.

Anesthesiology 2016 09;125(3):525-34

From the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (J.C.P.S., E.P., D.D.-.G., S.A.M., M.J.M., F.P.T., J.B.S., C.E.R., R.M.K., M.E.); Department of Orthopaedic and Trauma Surgery, University of Cologne, Cologne, Germany (J.C.P.S.); Department of Anesthesiology, University of Copenhagen, Herlev Hospital, Copenhagen, Denmark (J.B.S.); Department of Respiratory Care, Harvard Medical School, Boston, Massachusetts (R.M.K.); and Department of Anesthesia and Critical Care, University of Essen, Essen, Germany (M.E.).

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http://dx.doi.org/10.1097/ALN.0000000000001225DOI Listing
September 2016

Reversing neuromuscular blockade: inhibitors of the acetylcholinesterase versus the encapsulating agents sugammadex and calabadion.

Expert Opin Pharmacother 2016 14;17(6):819-33. Epub 2016 Mar 14.

a Department of Anesthesia, Critical Care and Pain Medicine , Massachusetts General Hospital and Harvard Medical School , Boston , MA , USA.

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http://dx.doi.org/10.1517/14656566.2016.1145667DOI Listing
August 2016

A Novel Strategy to Reverse General Anesthesia by Scavenging with the Acyclic Cucurbit[n]uril-type Molecular Container Calabadion 2.

Anesthesiology 2016 08;125(2):333-45

From the Anesthesia, Critical Care and Pain Medicine (D.D.-G., F.H., J.C.P.S., S.D.G., I.M.D., J.F.C., M.E.), Radiology (K.E.-H.), and Biostatistics (H.D.), Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts; Cell Biology and Molecular Genetics (S.F., G.K.H., V.B.) and Chemistry and Biochemistry (S.G., B.Z., L.I.), University of Maryland, College Park, Maryland; Neurology, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, Massachusetts (N.L.C.); and Anesthesia and Critical Care Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany (M.E.).

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http://dx.doi.org/10.1097/ALN.0000000000001199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4955735PMC
August 2016

Society of Anesthesia and Sleep Medicine Guidelines on Preoperative Screening and Assessment of Adult Patients With Obstructive Sleep Apnea.

Anesth Analg 2016 08;123(2):452-73

From the *Department of Anesthesiology, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada; †Department of Anesthesiology, Weill Cornell Medical College and Hospital for Special Surgery, New York, New York; ‡Department of Anesthesiology, University of Michigan, Ann Arbor, Michigan; §Department of Anesthesiology and Perioperative Medicine, University Hospital, St. Joseph's Hospital and Victoria Hospital, London Health Sciences Centre and St. Joseph's Health care, Western University, London, Ontario, Canada; ‖Paracelsus Medical University, Department of Anesthesiology, Perioperative Medicine and Intensive Care, Salzburg, Austria; ¶Department of Anesthesiology, Hospital for Special Surgery, Weill Cornell Medical College New York, New York; #Department of Anesthesia, Perioperative Medicine and Intensive Care, Paracelsus Medical University, Salzburg, Austria; **Department of Medicine, University of California San Diego, San Diego, California; ††Sparrow Hospital, Lansing, Michigan; ‡‡Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical School, Texas; §§Department of Medicine, Division of Respiratory Medicine, The University of British Columbia, Vancouver, BC, Canada; ‖‖University of British Columbia, Vancouver, BC, Canada; ¶¶Department of Medicine, Emory University, Atlanta, Georgia; ##Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University Medical Center, Palo Alto, California; ***Department of Anesthesia, Critical Care and Pain Medicine, Harvard University, Cambridge, Massachusetts; †††Library and Information Services, University Health Network, University of Toronto, Toronto, Ontario, Canada; ‡‡‡Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota; §§§Department of Pulmonary, Critical Care and Sleep Medicine, Mayo Clinic, Rochester, Minnesota; ‖‖‖School of Medicine, Universidad Peruana de Ciencias Apl

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http://dx.doi.org/10.1213/ANE.0000000000001416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956681PMC
August 2016

Continuous Positive Airway Pressure Mitigates Opioid-induced Worsening of Sleep-disordered Breathing Early after Bariatric Surgery.

Anesthesiology 2016 Jul;125(1):92-104

From the Department of Anesthesia, Critical Care and Pain Medicine (S.Z., C.H.S., S.A.M., S.D.G., T.M., D.D-.G., M.E.), Department of Surgery (M.M.H.), and Respiratory Care, Department of Anesthesia, Critical Care and Pain Medicine (D.H.), Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts; Sleep Medicine, Department of Neurology, Rheinische Friedrich-Wilhelms-University, Bonn, Germany (S.Z.); German Center for Neurodegenerative Diseases (DZNE) within the Helmholtz Association, Bonn, Germany (S.Z.); Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, Michigan (S.K.R.); Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California San Diego, La Jolla, California (A.M.); and Department of Anesthesia and Critical Care, University Hospital Essen, Essen, Germany (M.E.).

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http://dx.doi.org/10.1097/ALN.0000000000001160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321128PMC
July 2016

Obstructive Sleep Apnea-a Perioperative Risk Factor.

Dtsch Arztebl Int 2016 Jul;113(27-28):463-9

Clinic for Anesthesiology and Intensive Care & Essen University Hospital, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, USA, und Universität Duisburg-Essen, Department of Interventional Pneumology, Ruhrlandklinik, University Hospital Essen.

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http://dx.doi.org/10.3238/arztebl.2016.0463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973000PMC
July 2016

In Reply.

Anesthesiology 2016 06;124(6):1417-8

Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (M.E.).

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http://dx.doi.org/10.1097/ALN.0000000000001098DOI Listing
June 2016

Significant but reasonable radiation exposure from computed tomography-related medical imaging in the ICU.

Emerg Radiol 2016 Apr 6;23(2):141-6. Epub 2016 Jan 6.

Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1007/s10140-015-1373-yDOI Listing
April 2016

The German Validation Study of the Surgical Intensive Care Unit Optimal Mobility Score.

J Crit Care 2016 Apr 30;32:201-6. Epub 2015 Dec 30.

Klinik für Anaesthesiologie, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

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http://dx.doi.org/10.1016/j.jcrc.2015.12.020DOI Listing
April 2016

Effects of parecoxib on analgesia benefit and blood loss following open prostatectomy: a multicentre randomized trial.

BMC Anesthesiol 2015 9;15:31. Epub 2015 Mar 9.

Klinik für Anästhesiologie und Intensivmedizin, Universität Duisburg-Essen, Universitätsklinikum Essen, Hufelandstrasse 55, Essen, D-45144 Germany ; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114 USA.

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http://dx.doi.org/10.1186/s12871-015-0015-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4357198PMC
March 2016

Prospective Observational Study of Predictors of Re-Intubation Following Extubation in the Surgical ICU.

Respir Care 2016 Mar 10;61(3):306-15. Epub 2015 Nov 10.

Department of Anesthesiology, University of California San Diego, San Diego, California.

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http://dx.doi.org/10.4187/respcare.04269DOI Listing
March 2016

Perioperative sleep apnea: a real problem or did we invent a new disease?

F1000Res 2016 11;5. Epub 2016 Jan 11.

Department of Anaesthesia Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, 02114, USA; Department of Anaesthesia and Critical Care, University Hospital Essen, Essen, 45147, Germany.

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http://dx.doi.org/10.12688/f1000research.7218.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797892PMC
March 2016

Acquired Muscle Weakness in the Surgical Intensive Care Unit: Nosology, Epidemiology, Diagnosis, and Prevention.

Anesthesiology 2016 Jan;124(1):207-34

From the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (H.F., I.M.-D., M.E.); Department of Anesthesia and Critical Care Medicine, Section of Neuroanesthesia and Neurocritical Care, University of Brescia at Spedali Civili, Brescia, Italy (N.L.); Department of Physical Medicine and Rehabilitation, Massachusetts General Hospital, Spaulding Rehabilitation Hospital and Harvard Medical School, Boston, Massachusetts (R.Z.); and Klinik für Anästhesiologie und Intensivmedizin, Universitaetsklinikum Essen, Essen, Germany (M.E.).

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http://dx.doi.org/10.1097/ALN.0000000000000874DOI Listing
January 2016

Noise Levels in Surgical ICUs Are Consistently Above Recommended Standards.

Crit Care Med 2016 Jan;44(1):147-52

1Division of Critical Care, Department of Emergency Medicine and Department of Anesthesiology, University of California, San Diego, San Diego, CA.2Massachusetts General Hospital, Boston, MA.3Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, MA.4Department of Anesthesiology, Ohio State University, Columbus, OH.5Department of Surgery, Massachusetts General Hospital, Boston, MA.6Department of Surgery and Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA.

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http://dx.doi.org/10.1097/CCM.0000000000001378DOI Listing
January 2016

In Vitro selectivity of an acyclic cucurbit[n]uril molecular container towards neuromuscular blocking agents relative to commonly used drugs.

Org Biomol Chem 2016 Jan 9;14(4):1277-87. Epub 2015 Dec 9.

Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, USA.

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http://dx.doi.org/10.1039/c5ob02356dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720557PMC
January 2016

Effects of obstructive sleep apnoea risk on postoperative respiratory complications: protocol for a hospital-based registry study.

BMJ Open 2016 Jan 13;6(1):e008436. Epub 2016 Jan 13.

Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/bmjopen-2015-008436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735131PMC
January 2016

The Surgical Optimal Mobility Score predicts mortality and length of stay in an Italian population of medical, surgical, and neurologic intensive care unit patients.

J Crit Care 2015 Dec 5;30(6):1251-7. Epub 2015 Aug 5.

Department of Anesthesia, Critical Care Medicine and Emergency, Spedali Civili University Hospital, Brescia, Italy; Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Brescia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2015.08.002DOI Listing
December 2015

Comparative Effectiveness of Calabadion and Sugammadex to Reverse Non-depolarizing Neuromuscular-blocking Agents.

Anesthesiology 2015 Dec;123(6):1337-49

From the Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (F.H., J.C.P.S., I.M.D., D.D.-G., M.E.); Clinic of Anesthesiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany (U.F., M.B.); Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland (S.G., B.Z., L.I.); Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (K.E.-H., C.A.); and Department of Anesthesia and Critical Care Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany (M.E.).

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http://dx.doi.org/10.1097/ALN.0000000000000868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679413PMC
December 2015

Codifying healthcare--big data and the issue of misclassification.

BMC Anesthesiol 2015 Dec 15;15:179. Epub 2015 Dec 15.

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02115, United States.

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http://dx.doi.org/10.1186/s12871-015-0165-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678724PMC
December 2015

Elevated upper body position improves pregnancy-related OSA without impairing sleep quality or sleep architecture early after delivery.

Chest 2015 Oct;148(4):936-944

Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA; Department of Anesthesia and Critical Care Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany. Electronic address:

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http://dx.doi.org/10.1378/chest.14-2973DOI Listing
October 2015

The Deyo-Charlson and Elixhauser-van Walraven Comorbidity Indices as predictors of mortality in critically ill patients.

BMJ Open 2015 Sep 8;5(9):e008990. Epub 2015 Sep 8.

Division of Trauma, Emergency Surgery and Surgical Critical Care, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2015-00899
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http://dx.doi.org/10.1136/bmjopen-2015-008990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563218PMC
September 2015

Authors' reply to Whitlock and Saied and colleagues.

BMJ 2015 Sep 30;351:h5143. Epub 2015 Sep 30.

Department of Anesthesia, Critical Care, Pain Medicine, Massachusetts General Hospital, Boston, MA 02114, USA

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http://dx.doi.org/10.1136/bmj.h5143DOI Listing
September 2015

Apply Protective Mechanical Ventilation in the Operating Room in an Individualized Approach to Perioperative Respiratory Care.

Anesthesiology 2015 Jul;123(1):12-4

From the Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (M.E.); and Inserm Research Center for Epidemiology and Biostatistics (U897)-Team Neuroepidemiology, College of Health Sciences, University of Bordeaux, Bordeaux, France (T.K.).

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/ALN.0000000000000707DOI Listing
July 2015

Intraoperative protective mechanical ventilation and risk of postoperative respiratory complications: hospital based registry study.

BMJ 2015 Jul 14;351:h3646. Epub 2015 Jul 14.

Department of Anesthesia, Critical Care, Pain Medicine, Massachusetts General Hospital, Boston, MA 02114, USA Essen-Duisburg University, Essen, Germany

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501577PMC
http://dx.doi.org/10.1136/bmj.h3646DOI Listing
July 2015

Eliminate postoperative respiratory complications: preoperative screening opens the door to clinical pathways that individualise perioperative treatment.

Eur J Anaesthesiol 2015 Jul;32(7):455-7

From the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA and Department of Anaesthesiology, University of Copenhagen, Herlev Hospital, Herlev, Denmark (AKS-R), and Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA and Universität Duisburg Essen, Essen, Germany (ME).

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http://dx.doi.org/10.1097/EJA.0000000000000210DOI Listing
July 2015

In Reply.

Anesthesiology 2015 Jul;123(1):233-4

Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (M.J.M.).

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http://dx.doi.org/10.1097/ALN.0000000000000679DOI Listing
July 2015

Advanced imaging use in intensive care units has decreased, resulting in lower charges without negative effects on patient outcomes.

J Crit Care 2015 Jun 24;30(3):460-4. Epub 2014 Dec 24.

Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2014.12.012DOI Listing
June 2015

Dose-dependent Association between Intermediate-acting Neuromuscular-blocking Agents and Postoperative Respiratory Complications.

Anesthesiology 2015 Jun;122(6):1201-13

From the Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts (D.J.M., D.D.-G., H.N.F., K.S.L., M.E.); Inserm Research Center for Epidemiology and Biostatistics (U897)-Team Neuroepidemiology, Bordeaux, France (T.K.); University of Bordeaux, College of Health Sciences, Bordeaux, France (T.K.); Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts (T.K.); and Universitaetsklinkum Duisburg-Essen, Essen, Germany (M.E.).

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http://dx.doi.org/10.1097/ALN.0000000000000674DOI Listing
June 2015

Anesthesia and increased hypercarbic drive impair the coordination between breathing and swallowing.

Anesthesiology 2014 Dec;121(6):1175-83

From the Department of Anesthesia, Critical Care, and Pain Medicine, Carl Rosow Clinical Research Center, Massachusetts General Hospital, Boston, Massachusetts (O.M.D., D.D.-G., J.C.P.S., C.G., N.M., M.J.M., E.P., C.R., M.E.); Department of Speech, Language, and Swallowing Disorders, Massachusetts General Hospital, Boston, Massachusetts (D.N.); and Universitätsklinikum Essen, Klinik für Anästhesie und Intensivmedizin, Essen, Germany (M.E.).

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http://dx.doi.org/10.1097/ALN.0000000000000462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464404PMC
December 2014

Residual Paralysis: Does it Influence Outcome After Ambulatory Surgery?

Curr Anesthesiol Rep 2014 Dec;4(4):290-302

Department of Anesthesia, Critical Care and Pain Medicine, Harvard Medical School, Massachusetts General Hospital, 55, Fruit Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1007/s40140-014-0073-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267566PMC
December 2014

Etomidate and Ketamine: Residual Motor and Adrenal Dysfunction that Persist beyond Recovery from Loss of Righting Reflex in Rats.

Pharmaceuticals (Basel) 2014 Dec 29;8(1):21-37. Epub 2014 Dec 29.

Department of Anesthesia Critical Care and Pain Medicine, Massachusetts General Hospital, 55 Fruit Street, Boston, MA-02114 and Klinik fuer Anaesthesie und Intensivmedizin, Universitaetsklinikum Essen, 45147 Essen, Germany.

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http://dx.doi.org/10.3390/ph8010021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381199PMC
December 2014

Effects of neostigmine reversal of nondepolarizing neuromuscular blocking agents on postoperative respiratory outcomes: a prospective study.

Anesthesiology 2014 Nov;121(5):959-68

From the Department of Emergency and Critical Care Medicine, Showa General Hospital, Tokyo, Japan (N.S.); Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (M.J.M.); Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts (S.A.M., A.B.S., A.H.H.); MGH Anesthesia Research Grants, BWH Department of Preventive Medicine, and Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts (A.I.); Massachusetts General Hospital, Boston, Massachusetts (T.M., M.E.D.); and Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, and Klinik fuer Anaesthesie und Intensivmedizin, Universitaetsklinikum Essen, Essen, Germany (M.E.).

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http://dx.doi.org/10.1097/ALN.0000000000000440DOI Listing
November 2014

Mandatory health care insurance is associated with shorter hospital length of stay among critically injured trauma patients.

J Trauma Acute Care Surg 2014 Aug;77(2):298-303

From the Division of Trauma Emergency Surgery and Surgical Critical Care (J.L., M.S., H.K., E.K., D.D.Y., M.D, G.V.), and Department of Anesthesia, Critical Care and Pain Medicine (M.E.), Massachusetts General Hospital & Harvard Medical School, Boston, Massachusetts; Inserm Research Center for Epidemiology and Biostatistics (U897) (T.K.); University of Bordeaux (T.K.), Bordeaux, France; Icahn School of Medicine of Mount Sinai (K.S.), New York, New York; and Department of Emergency Medicine (A.S.R.), Brigham and Women's Hospital & Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1097/TA.0000000000000334DOI Listing
August 2014

Elevated body position early after delivery increased airway size during wakefulness, and decreased apnea hypopnea index in a woman with pregnancy related sleep apnea.

J Clin Sleep Med 2014 Jul 15;10(7):815-7. Epub 2014 Jul 15.

Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA ; Department of Anesthesia and Critical Care, University Hospital Essen, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.5664/jcsm.3886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067449PMC
July 2014

Therapeutic range of spontaneous breathing during mechanical ventilation.

Anesthesiology 2014 Mar;120(3):536-9

From the Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, and Klinik fuer Anaesthesiologie und Intensivmedizin, Universitaetsklinikum Essen, Dusiburg-Essen University, Essen, Germany (M.E.); and Department of Anesthesiology, Critical Care, and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (M.F.V.M.).

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http://dx.doi.org/10.1097/ALN.0000000000000126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3985085PMC
March 2014

Facemask ventilation during induction of anesthesia: how "gentle" is "gentle" enough?

Anesthesiology 2014 Feb;120(2):263-5

From the Department of Anesthesiology, Graduate School of Medicine, Chiba University, Chiba, Japan (S.I.); Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (M.E.); and Department of Endoscopic Diagnostics and Therapeutics, Chiba University Hospital, Chiba, Japan (T.O.).

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http://dx.doi.org/10.1097/ALN.0000000000000095DOI Listing
February 2014

What is new in prevention of muscle weakness in critically ill patients?

Intensive Care Med 2013 Dec 24;39(12):2200-3. Epub 2013 Oct 24.

Department of Anesthesia, Critical Care and Pain Medicine at Massachusetts General Hospital, and Harvard Medical School, 55 Fruit Street, Boston, MA, 02115, USA,

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http://link.springer.com/10.1007/s00134-013-3132-4
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http://dx.doi.org/10.1007/s00134-013-3132-4DOI Listing
December 2013

In reply.

Anesthesiology 2013 Oct;119(4):994-5

*Massachusetts General Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1097/ALN.0b013e3182a462b1DOI Listing
October 2013

Muscle weakness and nutrition in critical illness: matching nutrient supply and use.

Lancet Respir Med 2013 Oct 10;1(8):589-590. Epub 2013 Sep 10.

Department of Anaesthesia, Critical Care and Pain Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA; Klinik fuer Anaesthesiologie und Intensivmedizin, Essen-Duisburg University, Essen, Germany.

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http://dx.doi.org/10.1016/S2213-2600(13)70148-6DOI Listing
October 2013

Calabadion: A new agent to reverse the effects of benzylisoquinoline and steroidal neuromuscular-blocking agents.

Anesthesiology 2013 Aug;119(2):317-25

Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts, USA.

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http://anesthesiology.pubs.asahq.org/Article.aspx?doi=10.109
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http://dx.doi.org/10.1097/ALN.0b013e3182910213DOI Listing
August 2013

Muscle weakness predicts pharyngeal dysfunction and symptomatic aspiration in long-term ventilated patients.

Anesthesiology 2013 Aug;119(2):389-97

Department of Anesthesia, Critical Care, and Pain Medicine and Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/ALN.0b013e31829373feDOI Listing
August 2013

Development and validation of a score for prediction of postoperative respiratory complications.

Anesthesiology 2013 Jun;118(6):1276-85

Department of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1097/ALN.0b013e318293065cDOI Listing
June 2013