Publications by authors named "Matthias Bieg"

24Publications

Unraveling most abundant mutational signatures in head and neck cancer.

Int J Cancer 2020 Sep 15. Epub 2020 Sep 15.

Section Experimental and Translational Head and Neck Oncology, Department of Otolaryngology, Head and Neck Surgery, University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.33297DOI Listing
September 2020

Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenocarcinoma Reveals Predictive Aberrant Methylation in the Promoter Region of the Long Noncoding RNA PLUT: An Exploratory Study.

J Thorac Oncol 2020 Aug 7;15(8):1338-1350. Epub 2020 Apr 7.

Translational Lung Research Centre Heidelberg, Member of the German Centre for Lung Research (Deutsches Zentrum für Lungenforschung), Heidelberg, Germany; Translational Research Unit, Thoraxklinik at University Hospital Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.jtho.2020.03.023DOI Listing
August 2020

Integrative Analysis of Multi-omics Data Identified EGFR and PTGS2 as Key Nodes in a Gene Regulatory Network Related to Immune Phenotypes in Head and Neck Cancer.

Clin Cancer Res 2020 Jul 11;26(14):3616-3628. Epub 2020 Mar 11.

Department of Otorhinolaryngology, Head and Neck Surgery, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-3997DOI Listing
July 2020

Impact of cancer mutational signatures on transcription factor motifs in the human genome.

BMC Med Genomics 2019 05 20;12(1):64. Epub 2019 May 20.

Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany.

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http://dx.doi.org/10.1186/s12920-019-0525-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6528224PMC
May 2019

Early-onset childhood atopic dermatitis is related to NLRP2 repression.

J Allergy Clin Immunol 2018 04 9;141(4):1482-1485.e16. Epub 2017 Dec 9.

Department of Environmental Immunology, Helmholtz Centre for Environmental Research Leipzig, Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.11.018DOI Listing
April 2018

The whole-genome landscape of medulloblastoma subtypes.

Nature 2017 07;547(7663):311-317

Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature22973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905700PMC
July 2017

Recurrent Somatic PDGFRB Mutations in Sporadic Infantile/Solitary Adult Myofibromas But Not in Angioleiomyomas and Myopericytomas.

Am J Surg Pathol 2017 Feb;41(2):195-203

*Institute of Pathology ¶Department of Paediatrics, University Hospital, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen †Division of Theoretical Bioinformatics (B080) #Division Molecular Genome Analysis **Genomics & Proteomics Core Facility, German Cancer Research Center (DKFZ), Heidelberg §Institute of Pathology, St. Vincent's Hospital, Karlsruhe ∥Institute of Pathology, Klinikum Augsburg, Augsburg ‡‡Dermatopathologische Gemeinschaftspraxis, Friedrichshafen, Germany ‡Department of Pathology, Faculty of Medicine in Plzen and Charles University Hospital, Biomedical Center ††Department of Pathology, Faculty of Medicine, Charles University, Plzen, Czech Republic.

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http://dx.doi.org/10.1097/PAS.0000000000000752DOI Listing
February 2017

Increased vitamin D levels at birth and in early infancy increase offspring allergy risk-evidence for involvement of epigenetic mechanisms.

J Allergy Clin Immunol 2016 Feb 15;137(2):610-3. Epub 2015 Aug 15.

Department of Environmental Immunology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany; Core Facility Studies, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.06.040DOI Listing
February 2016

Aberrant DNA hypermethylation of SDHC: a novel mechanism of tumor development in Carney triad.

Endocr Relat Cancer 2014 Aug 23;21(4):567-77. Epub 2014 May 23.

Institute of PathologyUniversity Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Krankenhausstraße 8-10, D-91054 Erlangen, GermanyProgram on Developmental Endocrinology and GeneticsEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USADivision Molecular Genome AnalysisDivision of Theoretical BioinformaticsGerman Cancer Research Center (DKFZ), Heidelberg, GermanyInstitut CochinINSERM U1016, CNRS UMR 8104, Université Paris Descartes, Sorbonne Paris Cité, Paris, FranceDepartment of EndocrinologyReferal Center for Rare Adrenal Diseases, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, FranceInstitute of PathologyUniversity Medical Center, Georg-August University, Göttingen, GermanyInstitute of PathologyUniversity Hospital, Albert-Ludwigs University Freiburg, Freiburg, GermanySchool of Clinical and Experimental MedicineCollege of Medical and Dental Sciences, Centre for Rare Diseases and Personalised Medicine, Birmingham Women's Hospital, University of Birmingham and West Midlands Regional Genetics Service, Birmingham, UKDepartment of Medical GeneticsUniversity of Cambridge, Cambridge CB2 0QQ, UKLaboratory Medicine and PathologyEmeritus Staff, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1530/ERC-14-0254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722532PMC
August 2014

Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia.

Cancer Discov 2014 Mar 19;4(3):348-61. Epub 2013 Dec 19.

Divisions of 1Epigenomics and Cancer Risk Factors, 2Theoretical Bioinformatics, 3Biostatistics, and 4Molecular Genetics; 5Department of Translational Oncology, National Center for Tumor Diseases (NCT), The German Cancer Research Center (DKFZ); 6Department of Medicine V, University of Heidelberg, Heidelberg; 7Department of Medicine, University of Freiburg Medical Center, Freiburg; 8Department of Internal Medicine III, University of Ulm, Ulm; 9The German Cancer Consortium, Germany; 10Department of Medicine, University of California at San Diego Moores Cancer Center, La Jolla, California; and 11Division of Hematology, The Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134522PMC
March 2014

Imprinted genes show unique patterns of sequence conservation.

BMC Genomics 2010 Nov 22;11:649. Epub 2010 Nov 22.

Universität des Saarlandes, Saarbrücken, Germany.

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http://dx.doi.org/10.1186/1471-2164-11-649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091771PMC
November 2010

Divergence of imprinted genes during mammalian evolution.

BMC Evol Biol 2010 Apr 29;10:116. Epub 2010 Apr 29.

Lehrstuhl für Computational Biology, Universität des Saarlandes, D-66041 Saarbrücken, Germany.

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http://dx.doi.org/10.1186/1471-2148-10-116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875234PMC
April 2010