Publications by authors named "Matthias A Karajannis"

68Publications

Letter to the Editor regarding clinical debate concerning treatment of pediatric LGG by Cooney et al.

Neurooncol Pract 2020 Oct 16;7(5):569-570. Epub 2020 Jul 16.

Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York.

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October 2020

Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.

Authors:
Matthew Clarke Alan Mackay Britta Ismer Jessica C Pickles Ruth G Tatevossian Scott Newman Tejus A Bale Iris Stoler Elisa Izquierdo Sara Temelso Diana M Carvalho Valeria Molinari Anna Burford Louise Howell Alex Virasami Amy R Fairchild Aimee Avery Jane Chalker Mark Kristiansen Kelly Haupfear James D Dalton Wilda Orisme Ji Wen Michael Hubank Kathreena M Kurian Catherine Rowe Mellissa Maybury Stephen Crosier Jeffrey Knipstein Ulrich Schüller Uwe Kordes David E Kram Matija Snuderl Leslie Bridges Andrew J Martin Lawrence J Doey Safa Al-Sarraj Christopher Chandler Bassel Zebian Claire Cairns Rachael Natrajan Jessica K R Boult Simon P Robinson Martin Sill Ira J Dunkel Stephen W Gilheeney Marc K Rosenblum Debbie Hughes Paula Z Proszek Tobey J Macdonald Matthias Preusser Christine Haberler Irene Slavc Roger Packer Ho-Keung Ng Shani Caspi Mara Popović Barbara Faganel Kotnik Matthew D Wood Lissa Baird Monika Ashok Davare David A Solomon Thale Kristin Olsen Petter Brandal Michael Farrell Jane B Cryan Michael Capra Michael Karremann Jens Schittenhelm Martin U Schuhmann Martin Ebinger Winand N M Dinjens Kornelius Kerl Simone Hettmer Torsten Pietsch Felipe Andreiuolo Pablo Hernáiz Driever Andrey Korshunov Lotte Hiddingh Barbara C Worst Dominik Sturm Marc Zuckermann Olaf Witt Tabitha Bloom Clare Mitchell Evelina Miele Giovanna Stefania Colafati Francesca Diomedi-Camassei Simon Bailey Andrew S Moore Timothy E G Hassall Stephen P Lowis Maria Tsoli Mark J Cowley David S Ziegler Matthias A Karajannis Kristian Aquilina Darren R Hargrave Fernando Carceller Lynley V Marshall Andreas von Deimling Christof M Kramm Stefan M Pfister Felix Sahm Suzanne J Baker Angela Mastronuzzi Andrea Carai Maria Vinci David Capper Sergey Popov David W Ellison Thomas S Jacques David T W Jones Chris Jones

Cancer Discov 2020 Jul 1;10(7):942-963. Epub 2020 Apr 1.

Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.

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July 2020

Time to advance methylation profiling to the forefront of primary diagnostics for childhood brain tumours.

Lancet Child Adolesc Health 2020 02 27;4(2):93-95. Epub 2019 Nov 27.

Pediatric Neuro-Oncology Service, Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA. Electronic address:

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February 2020

Histone H3K36I mutation in a metastatic histiocytic tumor of the skull and response to sarcoma chemotherapy.

Cold Spring Harb Mol Case Stud 2019 10 23;5(5). Epub 2019 Oct 23.

Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA.

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October 2019

Subgroup-specific outcomes of children with malignant childhood brain tumors treated with an irradiation-sparing protocol.

Childs Nerv Syst 2020 01 2;36(1):133-144. Epub 2019 Aug 2.

Pediatric Neuro-Oncology, Department of Pediatrics, Hassenfeld Children's Hospital, NYU Langone Health, New York, USA.

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January 2020

Sustained imaging response and hearing preservation with low-dose bevacizumab in sporadic vestibular schwannoma.

Neuro Oncol 2019 06;21(6):822-824

Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York.

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June 2019

Effect of lapatinib on meningioma growth in adults with neurofibromatosis type 2.

J Neurooncol 2018 Sep 8;139(3):749-755. Epub 2018 Jun 8.

Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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September 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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March 2018

Patterns of relapse for children with localized intracranial ependymoma.

J Neurooncol 2018 Jun 6;138(2):435-445. Epub 2018 Mar 6.

Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.

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June 2018

Pre-treatment lymphopenia and indication of tumor-induced systemic immunosuppression in medulloblastoma.

J Neurooncol 2018 Feb 16;136(3):541-544. Epub 2017 Nov 16.

Department of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Box 234, New York, NY, 10065, USA.

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February 2018

Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2.

Cell Rep 2017 Oct;21(5):1267-1280

Department of Neurosurgery, NYU School of Medicine, New York, NY 10016, USA; Kimmel Center for Stem Cell Biology, NYU School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, NYU School of Medicine, New York, NY 10016, USA; Brain Tumor Center, NYU School of Medicine, New York, NY 10016, USA; Neuroscience Institute, NYU School of Medicine, New York, NY 10016, USA. Electronic address:

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October 2017

Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas.

J Clin Oncol 2017 Sep 20;35(25):2934-2941. Epub 2017 Jul 20.

Alvaro Lassaletta, Michal Zapotocky, Matthew Mistry, Vijay Ramaswamy, Marion Honnorat, Rahul Krishnatry, Ana Guerreiro Stucklin, Nataliya Zhukova, Anthony Arnoldo, Scott Ryall, Catriona Ling, Tara McKeown, Jim Loukides, James T. Rutka, Peter Dirks, Michael D. Taylor, Shiyi Chen, Ute Bartels, Annie Huang, Eric Bouffet, Cynthia Hawkins, and Uri Tabori, The Hospital for Sick Children, Toronto; Adam Fleming, McMaster Children's Hospital, McMaster University, Hamilton; Shayna Zelcer, Children's Hospital of Western Ontario, London, Ontario; David Eisenstat and Bev Wilson, Stollery Children's Hospital, University of Alberta, Edmonton, Alberta; Anne Sophie Carret, Hospital Sainte Justine; Nada Jabado, McGill University, Montreal; Valerie Larouche, Centre Hospitalier Universitaire de Québec, Québec City, Quebec, Canada; Ofelia Cruz and Carmen de Torres, Hospital Sant Joan de Déu, Barcelona, Spain; Cheng-Ying Ho, University of Maryland School of Medicine, Baltimore, MD; Roger J. Packer, Children's National Health System, Washington, DC; Ruth Tatevossian, Ibrahim Qaddoumi, Julie H. Harreld, James D. Dalton, and David W. Ellison, St Jude Children's Research Hospital, Memphis, TN; Jean Mulcahy-Levy and Nicholas Foreman, Children's Hospital Colorado, Aurora, CO; Matthias A. Karajannis, Shiyang Wang, and Matija Snuderl, New York University Langone Medical Center, New York, NY; Amulya Nageswara Rao and Caterina Giannini, The Mayo Clinic, Rochester, MN; Mark Kieran and Keith L. Ligon, Dana-Farber Cancer Institute, Boston Children's Hospital, Boston, MA; Maria Luisa Garre, Paolo Nozza, Samantha Mascelli, and Alessandro Raso, Istituto Giannina Gaslini, Genoa, Italy; Sabine Mueller and Theodore Nicolaides, University of California, San Francisco, San Francisco, CA; Karen Silva and Romain Perbet, Hospices Civils de Lyon; Alexandre Vasiljevic, Cécile Faure Conter, and Didier Frappaz, Institute of Pediatric Hematology and Oncology, Lyon, France; Sarah Leary and Courtney Crane, Seattle Children's Hospital, Seattle, WA; Aden Chan and Ho-Keung Ng, The Chinese University of Hong Kong, Hong Kong; Zhi-Feng Shi and Ying Mao, Huashan Hospital, Fudan University, Shanghai, People's Republic of China; Elizabeth Finch, University of North Carolina, School of Medicine, Chapel Hill, NC; Peter Hauser, Semmelweis University, Budapest, Hungary; and David Sumerauer and Lenka Krskova, University Hospital Motol, Charles University, 2nd Medical School, Prague, Czech Republic.

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September 2017

Endothelium-Independent Primitive Myxoid Vascularization Creates Invertebrate-Like Channels to Maintain Blood Supply in Optic Gliomas.

Am J Pathol 2017 Aug 9;187(8):1867-1878. Epub 2017 Jun 9.

Division of Neuropathology, Department of Pathology, New York University Langone Medical Center and Medical School, New York, New York; Department of Neurosurgery, New York University Langone Medical Center and Medical School, New York, New York; Microvascular and Molecular Neurooncology Laboratory, Department of Pathology, New York University Langone Medical Center, New York, New York. Electronic address:

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August 2017

Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses Loss-Driven Tumorigenesis.

Mol Cancer Ther 2017 08 3;16(8):1693-1704. Epub 2017 May 3.

Department of Cancer Biology and David H. Koch Center for Applied Research of Genitourinary Cancers, University of Texas MD Anderson Cancer Center, Houston, Texas.

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August 2017

A novel, potentially targetable TMEM106B-BRAF fusion in pleomorphic xanthoastrocytoma.

Cold Spring Harb Mol Case Stud 2017 03;3(2):a001396

Department of Pediatrics, Columbia University Medical Center, New York, New York 10032, USA.

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March 2017

Utility of MRI versus tumor markers for post-treatment surveillance of marker-positive CNS germ cell tumors.

J Neurooncol 2016 09 12;129(3):541-544. Epub 2016 Jul 12.

Division of Pediatric Hematology/Oncology, Department of Pediatrics and Otolaryngology, NYU Langone Medical Center and Perlmutter Cancer Center, New York, NY, USA.

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September 2016

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.

Authors:
Vijay Ramaswamy Thomas Hielscher Stephen C Mack Alvaro Lassaletta Tong Lin Kristian W Pajtler David T W Jones Betty Luu Florence M G Cavalli Kenneth Aldape Marc Remke Martin Mynarek Stefan Rutkowski Sridharan Gururangan Roger E McLendon Eric S Lipp Christopher Dunham Juliette Hukin David D Eisenstat Dorcas Fulton Frank K H van Landeghem Mariarita Santi Marie-Lise C van Veelen Erwin G Van Meir Satoru Osuka Xing Fan Karin M Muraszko Daniela P C Tirapelli Sueli M Oba-Shinjo Suely K N Marie Carlos G Carlotti Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Claudia C Faria Sofia Nunes Jaume Mora Ronald L Hamilton Peter Hauser Nada Jabado Kevin Petrecca Shin Jung Luca Massimi Massimo Zollo Giuseppe Cinalli László Bognár Almos Klekner Tibor Hortobágyi Sarah Leary Ralph P Ermoian James M Olson Jeffrey R Leonard Corrine Gardner Wieslawa A Grajkowska Lola B Chambless Jason Cain Charles G Eberhart Sama Ahsan Maura Massimino Felice Giangaspero Francesca R Buttarelli Roger J Packer Lyndsey Emery William H Yong Horacio Soto Linda M Liau Richard Everson Andrew Grossbach Tarek Shalaby Michael Grotzer Matthias A Karajannis David Zagzag Helen Wheeler Katja von Hoff Marta M Alonso Teresa Tuñon Ulrich Schüller Karel Zitterbart Jaroslav Sterba Jennifer A Chan Miguel Guzman Samer K Elbabaa Howard Colman Girish Dhall Paul G Fisher Maryam Fouladi Amar Gajjar Stewart Goldman Eugene Hwang Marcel Kool Harshad Ladha Elizabeth Vera-Bolanos Khalida Wani Frank Lieberman Tom Mikkelsen Antonio M Omuro Ian F Pollack Michael Prados H Ian Robins Riccardo Soffietti Jing Wu Phillipe Metellus Uri Tabori Ute Bartels Eric Bouffet Cynthia E Hawkins James T Rutka Peter Dirks Stefan M Pfister Thomas E Merchant Mark R Gilbert Terri S Armstrong Andrey Korshunov David W Ellison Michael D Taylor

J Clin Oncol 2016 07 6;34(21):2468-77. Epub 2016 Jun 6.

Vijay Ramaswamy, Stephen C. Mack, Alvaro Lassaletta, Betty Luu, Florence M.G. Cavalli, Uri Tabori, Ute Bartels, Eric Bouffet, Cynthia E. Hawkins, James T. Rutka, Peter Dirks, and Michael D. Taylor, The Hospital for Sick Children; Vijay Ramaswamy, Kenneth Aldape, James T. Rutka, and Michael D. Taylor, University of Toronto; Kenneth Aldape, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario; Christopher Dunham and Juliette Hukin, British Columbia Children's Hospital; Juliette Hukin, University of British Columbia, Vancouver, British Columbia; David D. Eisenstat, Dorcas Fulton, and Frank K.H. van Landeghem, University of Alberta, Edmonton; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Nada Jabado and Kevin Petrecca, McGill University, Montreal, Quebec, Canada; Thomas Hielscher, Kristian W. Pajtler, David T.W. Jones, Marcel Kool, Stefan M. Pfister, and Andrey Korshunov, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Marc Remke, University Hospital Düsseldorf, Düsseldorf; Martin Mynarek, Stefan Rutkowski, and Katja von Hoff, University Medical Center Hamburg-Eppendorf, Hamburg; Ulrich Schüller, Ludwig-Maximilians-Universität, Munich, Germany; Stephen C. Mack, Cleveland Clinic Foundation, Cleveland; Maryam Fouladi, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Tong Lin, Amar Gajjar, Thomas E. Merchant, and David W. Ellison, St Jude Children's Research Hospital, Memphis; Lola B. Chambless, Vanderbilt Medical Center, Nashville, TN; Sridharan Gururangan, Roger E. McLendon, and Eric S. Lipp, Duke University, Durham; Jing Wu, University of North Carolina at Chapel Hill, Chapel Hill, NC; Mariarita Santi, Children's Hospital of Philadelphia; Lyndsey Emery, Hospital of the University of Pennsylvania, Philadelphia; Ronald L. Hamilton and Ian F. Pollack, University of Pittsburgh School of Medicine; Frank Lieberman, University of Pittsburgh Medical Cen

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July 2016

Pediatric Brain Tumors: An Update.

Curr Probl Pediatr Adolesc Health Care 2016 Jul 24;46(7):242-250. Epub 2016 May 24.

Division of Pediatric Hematology/Oncology, Department of Pediatrics, New York, NY; Department of Otolaryngology, NYU Langone Medical Center, New York, NY; Perlmutter Cancer Center, New York, NY.

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July 2016

The promise of molecular profiling of choroid plexus tumors for diagnostic and prognostic stratification: where to go from here?

Neuro Oncol 2016 06 22;18(6):757-8. Epub 2016 Mar 22.

Department of Pediatrics, Division of Pediatric Hematology/Oncology, NYU Langone Medical Center, New York, New York (D.S., M.A.K.); Department of Otolaryngology, NYU Langone Medical Center, New York, New York (M.A.K.); Perlmutter Cancer Center, NYU Langone Medical Center, New York, New York (M.A.K.).

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June 2016

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.

Authors:
Dominik Sturm Brent A Orr Umut H Toprak Volker Hovestadt David T W Jones David Capper Martin Sill Ivo Buchhalter Paul A Northcott Irina Leis Marina Ryzhova Christian Koelsche Elke Pfaff Sariah J Allen Gnanaprakash Balasubramanian Barbara C Worst Kristian W Pajtler Sebastian Brabetz Pascal D Johann Felix Sahm Jüri Reimand Alan Mackay Diana M Carvalho Marc Remke Joanna J Phillips Arie Perry Cynthia Cowdrey Rachid Drissi Maryam Fouladi Felice Giangaspero Maria Łastowska Wiesława Grajkowska Wolfram Scheurlen Torsten Pietsch Christian Hagel Johannes Gojo Daniela Lötsch Walter Berger Irene Slavc Christine Haberler Anne Jouvet Stefan Holm Silvia Hofer Marco Prinz Catherine Keohane Iris Fried Christian Mawrin David Scheie Bret C Mobley Matthew J Schniederjan Mariarita Santi Anna M Buccoliero Sonika Dahiya Christof M Kramm André O von Bueren Katja von Hoff Stefan Rutkowski Christel Herold-Mende Michael C Frühwald Till Milde Martin Hasselblatt Pieter Wesseling Jochen Rößler Ulrich Schüller Martin Ebinger Jens Schittenhelm Stephan Frank Rainer Grobholz Istvan Vajtai Volkmar Hans Reinhard Schneppenheim Karel Zitterbart V Peter Collins Eleonora Aronica Pascale Varlet Stephanie Puget Christelle Dufour Jacques Grill Dominique Figarella-Branger Marietta Wolter Martin U Schuhmann Tarek Shalaby Michael Grotzer Timothy van Meter Camelia-Maria Monoranu Jörg Felsberg Guido Reifenberger Matija Snuderl Lynn Ann Forrester Jan Koster Rogier Versteeg Richard Volckmann Peter van Sluis Stephan Wolf Tom Mikkelsen Amar Gajjar Kenneth Aldape Andrew S Moore Michael D Taylor Chris Jones Nada Jabado Matthias A Karajannis Roland Eils Matthias Schlesner Peter Lichter Andreas von Deimling Stefan M Pfister David W Ellison Andrey Korshunov Marcel Kool

Cell 2016 Feb;164(5):1060-1072

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.

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February 2016

Pediatric Brain Tumors: Innovative Genomic Information Is Transforming the Diagnostic and Clinical Landscape.

J Clin Oncol 2015 Sep 24;33(27):2986-98. Epub 2015 Aug 24.

Amar Gajjar, St Jude Children's Research Hospital, Memphis, TN; Daniel C. Bowers, University of Texas Southwestern Medical Center, Dallas, TX; Matthias A. Karajannis, New York University (NYU) Perlmutter Cancer Center and NYU Langone Medical Center, New York, NY; Sarah Leary, University of Washington School of Medicine and Fred Hutchinson Cancer Research Center, Seattle, WA; Hendrik Witt, German Cancer Research Center and University of Heidelberg, Heidelberg, Germany; and Nicholas G. Gottardo, Princess Margaret Hospital for Children and The University of Western Australia, Perth, Western Australia, Australia.

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September 2015

Neurofibromatosis-related tumors: emerging biology and therapies.

Curr Opin Pediatr 2015 Feb;27(1):26-33

aDepartments of Pediatrics and Otolaryngology, Division of Pediatric Hematology/Oncology, NYU Langone Medical Center, New York, USA bDepartment of Neurology, Guy's and St Thomas' NHS Foundation Trust, and Department of Clinical Neuroscience, Institute of Psychiatry, King's College London, London, UK.

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February 2015

Clinical response to bevacizumab in schwannomatosis.

Neurology 2014 Nov 22;83(21):1986-7. Epub 2014 Oct 22.

From The Johns Hopkins Hospital (J.O.B., K.C.S., A.L.B., A.J.B.), Baltimore, MD; St. Mary's Hospital (D.G.E.), Manchester, UK; University of Alabama at Birmingham (B.K.); and NYU Langone Medical Center (D.Z., M.A.K.), New York.

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November 2014

Glioblastoma multiforme: State of the art and future therapeutics.

Surg Neurol Int 2014 8;5:64. Epub 2014 May 8.

Department of Neurosurgery, Division of Oncology, New York University School of Medicine, NY, USA.

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July 2014

Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas.

Neuro Oncol 2014 Oct 6;16(10):1408-16. Epub 2014 May 6.

NYU Comprehensive Neurofibromatosis Center, Division of Pediatric Hematology/Oncology, Department of Pediatrics and Laura and Isaac Perlmutter Cancer Center at NYU Langone Medical Center, New York, New York (M.A.K., G.L., A.M., J.C.A.); Division of Oncology, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania (M.J.F., A.J.S.); Department of Radiology, NYU Langone Medical Center, New York, New York (S.S.M., M.C.B.); The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland (K.J.C.); Division of Pediatric Neurosurgery, Department of Neurosurgery, NYU Langone Medical Center, New York, New York (J.H.W., D.H.H.); Division of Biostatistics, Department of Population Health and The Laura and Isaac Perlmutter Cancer Center at NYU Langone Medical Center, New York, New York (J.D.G., T.H.); Department of Neurosurgery, Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania (A.C.R); Division of Hematology/Oncology, Children's Hospital Los Angeles, Los Angeles, California (G.D.); German Cancer Research Center and University Hospital, Heidelberg, Germany (D.T.W.J., A.K., S.M.P.); Division of Neuropathology, Department of Pathology, Johns Hopkins University, Baltimore, Maryland (C.G.E.); Division of Neuropathology, Department of Pathology, Department of Neurosurgery and Laura and Isaac Perlmutter Cancer Center at NYU Langone Medical Center, New York, New York (D.Z.).

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October 2014

Recurrent ascites in a patient with low-grade astrocytoma and ventriculo-peritoneal shunt treated with the multikinase inhibitor sorafenib.

J Pediatr Hematol Oncol 2014 Nov;36(8):e533-5

Departments of *Pediatrics ∥Radiology, NYU Langone Medical Center, New York, NY Departments of †Pediatric Oncology §Neurosurgery, Boston Children's Hospital ‡Department of Pediatric Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA.

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November 2014

Phase II study of everolimus in children and adults with neurofibromatosis type 2 and progressive vestibular schwannomas.

Neuro Oncol 2014 Jan 4;16(2):292-7. Epub 2013 Dec 4.

Corresponding author: Matthias A. Karajannis, MD, MS, NYU Langone Medical Center, Hassenfeld Children's Center for Cancer and Blood Disorders, 160 East 32nd Street, 2nd floor, New York, NY 10016.

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January 2014

Recommendations for imaging tumor response in neurofibromatosis clinical trials.

Neurology 2013 Nov;81(21 Suppl 1):S33-40

From the Pediatric Oncology Branch (E.D., B.C.W.), National Cancer Institute, Bethesda, MD; Department of Neurology (S.L.A.-H.), The Children's Hospital at Westmead, Sydney, Australia; Department of Medical Genetics (D. B.-V.), Mayo Clinic, Rochester, MN; Neurosurgical Service (F.G.B.), Department of Radiology (G.J.H.), and Department of Neurology and Cancer Center (S.R.P.), Massachusetts General Hospital, Boston, MA; Department of Neuroradiology (S.C.), King's College Hospital, London, UK; Department of Genetic Medicine (D.G.E.), MAHSC, St Mary's Hospital, Manchester, UK; Division of Oncology (M.J.F.) and Department of Radiology (D.J.), The Children's Hospital of Philadelphia; Department of Pediatrics (M.J.F.), The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA; Department of Neurosurgery (S.G.), Hôpital Beaujon, Clichy, France; Division of Pediatric Hematology/Oncology and NYU Cancer Institute (M.A.K.), NYU Langone Medical Center, New York, NY; Department of Genetics (B.R.K.), University of Alabama at Birmingham, Birmingham, AL; Department of Neurology (V.M.), University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Radiology (T.Y.P.), Boston Children's Hospital, Boston, MA; and Department of Pediatrics (K.R., C.-S.S.), Riley Hospital for Children, Indianapolis, IN.

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November 2013

Activation of mTORC1/mTORC2 signaling in pediatric low-grade glioma and pilocytic astrocytoma reveals mTOR as a therapeutic target.

Neuro Oncol 2013 Dec 6;15(12):1604-14. Epub 2013 Nov 6.

Corresponding Authors: Fausto J. Rodriguez, MD, Division of Neuropathology, Johns Hopkins Hospital, 1800 Orleans Street, Baltimore, MD 21231. Eric H. Raabe, MD, PhD, Division of Neuropathology, Johns Hopkins Hospital, 1800 Orleans Street, Baltimore, MD 21231

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December 2013

Noncarboplatin-induced Sensorineural Hearing Loss in a Patient With an Intracranial Nongerminomatous Germ Cell Tumor.

J Pediatr Hematol Oncol 2016 05;38(4):312-6

*NYU Langone Medical Center, Hassenfeld Children's Center for Cancer and Blood Disorders †Department of Neurosurgery, NYU Langone Medical Center, New York, NY.

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May 2016

Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus.

EMBO Rep 2012 Mar;13(3):204-15

Cell Biology Program, Sloan–Kettering Institute for Cancer Research, Memorial Sloan–Kettering Cancer Center, 1275 York Avenue, Box 216, New York, New York 10065, USA.

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March 2012

Overexpression and activation of epidermal growth factor receptor in hemangioblastomas.

J Neurooncol 2010 Sep 22;99(2):195-200. Epub 2010 Feb 22.

Department of Pathology, New York University School of Medicine, New York, NY, USA.

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September 2010

ErbB/HER receptor activation and preclinical efficacy of lapatinib in vestibular schwannoma.

Neuro Oncol 2010 Aug 11;12(8):834-43. Epub 2010 Feb 11.

Division of Pediatric Hematology/Oncology and NYU Cancer Institute, Hassenfeld Children's Center for Cancer and Blood Disorders, 160 East 32nd Street, 2nd Floor, New York, NY 10016, USA.

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August 2010

The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death.

Blood 2008 Feb 16;111(4):1951-61. Epub 2007 Nov 16.

Howard Hughes Medical Institute, Ansary Center for Stem Cell Therapeutics, Department of Genetic Medicine, Division of Hematology-Oncology, Weill Cornell Medical College, New York, NY 10021, USA.

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February 2008