Matthew Wortham

Matthew Wortham

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Matthew Wortham

Matthew Wortham

Publications by authors named "Matthew Wortham"

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Beta-cell dysfunction induced by non-cytotoxic concentrations of Interleukin-1β is associated with changes in expression of beta-cell maturity genes and associated histone modifications.

Mol Cell Endocrinol 2019 10 27;496:110524. Epub 2019 Jul 27.

Department of Biomedical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark; Lead Contact Nils Billestrup, Department of Biomedical Science, University of Copenhagen, Copenhagen, 2200, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2019.110524DOI Listing
October 2019

High T Gives β Cells a Boost.

Cell Metab 2016 May;23(5):761-3

Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California San Diego, La Jolla, CA 92093-0695, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.04.015DOI Listing
May 2016

Chromatin accessibility mapping identifies mediators of basal transcription and retinoid-induced repression of OTX2 in medulloblastoma.

PLoS One 2014 8;9(9):e107156. Epub 2014 Sep 8.

Department of Pathology, The Pediatric Brain Tumor Foundation Institute, and The Preston Robert Tisch Brain Tumor Center at Duke, Duke University Medical Center, Durham, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107156PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157845PMC
January 2016

Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways.

Proc Natl Acad Sci U S A 2012 Oct 8;109(43):17603-8. Epub 2012 Oct 8.

The Preston Robert Tisch Brain Tumor Center at Duke, Pediatric Brain Tumor Foundation Institute, cDepartment of Pathology, Duke University, Durham, NC 27710, USA.

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http://dx.doi.org/10.1073/pnas.1208807109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491484PMC
October 2012

Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells.

PLoS One 2012 27;7(4):e36211. Epub 2012 Apr 27.

Department of Pathology, The Pediatric Brain Tumor Foundation Institute, and The Preston Robert Tisch Brain Tumor Center at Duke, Duke University Medical Center, Durham, North Carolina, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036211PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338642PMC
September 2012

Apples to origins: identifying brain tumor stem cell genes by comparing transcriptomes of normal and cancer stem cells.

Cancer Discov 2012 Jun;2(6):492-4

Department of Pathology, The Pediatric Brain Tumor Foundation Institute, and The Preston Robert Tisch Brain Tumor Center at Duke, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1158/2159-8290.CD-12-0182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375910PMC
June 2012

OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas.

Cancer Res 2010 Jan 22;70(1):181-91. Epub 2009 Dec 22.

Department of Surgery, The Pediatric Brain Tumor Foundation Institute, and The Preston Robert Tisch Brain Tumor Center at Duke, Duke University Medical Center, Veterans Affairs Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943736PMC
January 2010

The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet.

Dig Dis Sci 2008 Oct 26;53(10):2761-74. Epub 2008 Feb 26.

Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.

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http://link.springer.com/10.1007/s10620-007-0193-7
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http://dx.doi.org/10.1007/s10620-007-0193-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991247PMC
October 2008