Matthew T Wheeler

Matthew T Wheeler

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Matthew T Wheeler

Matthew T Wheeler

Publications by authors named "Matthew T Wheeler"

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Allele-Specific Silencing Ameliorates Restrictive Cardiomyopathy Attributable to a Human Myosin Regulatory Light Chain Mutation.

Circulation 2019 Aug 18;140(9):765-778. Epub 2019 Jul 18.

Division of Cardiovascular Medicine (K.Z.-R., A.D., P.C., G.R., C.S., J.L., T.F., W.N.P., S.S., K.S., N.S., N.J., Y.H., M.T.W., E.A.A.), Stanford University School of Medicine, CA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036965DOI Listing
August 2019

Expansion of the Human Phenotype Ontology (HPO) knowledge base and resources.

Nucleic Acids Res 2019 Jan;47(D1):D1018-D1027

Monarch Initiative, monarchinitiative.org.

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https://academic.oup.com/nar/advance-article/doi/10.1093/nar
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http://dx.doi.org/10.1093/nar/gky1105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324074PMC
January 2019

Effect of Genetic Diagnosis on Patients with Previously Undiagnosed Disease.

N Engl J Med 2018 11 10;379(22):2131-2139. Epub 2018 Oct 10.

From Harvard Medical School (K.S., C.E., I.S.K., J.L., A.T.M., D.A.S.), Brigham and Women's Hospital (J.L.), and Massachusetts General Hospital (D.A.S.) - all in Boston; the National Institutes of Health Clinical Center (D.R.A., W.A.G., J.J.M., C.J.T.) and the National Human Genome Research Institute (A.L.W.), Bethesda, and the University of Maryland, College Park (A.M.C.-J., B.K., L.P.) - all in Maryland; Baylor College of Medicine, Houston (C.A.B., H.J.B., C.M.E., B.H.L., X.L., M.F.W., S.Y.); Stanford University, Stanford (J.A.B., C.R., M.T.W., E.A.A.), and the University of California, Los Angeles, Los Angeles (S.F.N., C.G.S.P.) - both in California; Vanderbilt University, Nashville (R.H., J.A.P.); HudsonAlpha Institute for Biotechnology, Huntsville, AL (H.J.J., E.A.W.); Oregon Health and Science University, Portland (D.M.K.); the Pacific Northwest National Laboratory, Richland, WA (T.O.M.); the University of Oregon, Eugene (J.H.P., M.W.); and Duke University, Durham, NC (V.S., N.M.W.).

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http://www.nejm.org/doi/10.1056/NEJMoa1714458
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http://dx.doi.org/10.1056/NEJMoa1714458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481166PMC
November 2018

Genome Sequencing in Hypertrophic Cardiomyopathy.

J Am Coll Cardiol 2018 07;72(4):430-433

Center for Inherited Cardiovascular Disease, Stanford University, Stanford, California. Electronic address: https://twitter.com/MWheelerMD.

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http://dx.doi.org/10.1016/j.jacc.2018.05.029DOI Listing
July 2018

A New Approach to Rare Diseases of Children: The Undiagnosed Diseases Network.

J Pediatr 2018 05 11;196:291-297.e2. Epub 2018 Jan 11.

Stanford Center for Undiagnosed Diseases, Stanford University School of Medicine, Stanford, CA; Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2017.12.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924635PMC
May 2018

Value of Strain Imaging and Maximal Oxygen Consumption in Patients With Hypertrophic Cardiomyopathy.

Am J Cardiol 2017 Oct 17;120(7):1203-1208. Epub 2017 Jul 17.

Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California; Stanford Cardiovascular Institute, Stanford, California; Center for Inherited Cardiovascular Diseases, Stanford Hospital and Clinics, Stanford, California. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2017.06.070DOI Listing
October 2017

Repeats and Survival in Myotonic Dystrophy Type 1.

Circ Cardiovasc Genet 2017 06;10(3)

From the Center for Inherited Cardiovascular Diseases, Division of Cardiovascular Medicine, Stanford University School of Medicine and Center for Undiagnosed Diseases, Stanford University, Stanford, CA.

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http://dx.doi.org/10.1161/CIRCGENETICS.117.001783DOI Listing
June 2017

Accuracy in Wrist-Worn, Sensor-Based Measurements of Heart Rate and Energy Expenditure in a Diverse Cohort.

J Pers Med 2017 May 24;7(2). Epub 2017 May 24.

Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA 94305, USA.

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http://dx.doi.org/10.3390/jpm7020003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491979PMC
May 2017

Exercise restrictions trigger psychological difficulty in active and athletic adults with hypertrophic cardiomyopathy.

Open Heart 2016 17;3(2):e000488. Epub 2016 Oct 17.

Stanford Center for Inherited Cardiovascular Disease, Stanford University School of Medicine , Stanford, California , USA.

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http://dx.doi.org/10.1136/openhrt-2016-000488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073663PMC
October 2016

Sports genetics moving forward: lessons learned from medical research.

Physiol Genomics 2016 Mar 12;48(3):175-82. Epub 2016 Jan 12.

Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, California; Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Stanford University, Stanford, California; Department of Genetics, Stanford University, Stanford, California.

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http://dx.doi.org/10.1152/physiolgenomics.00109.2015DOI Listing
March 2016

Medical implications of technical accuracy in genome sequencing.

Genome Med 2016 Mar 2;8(1):24. Epub 2016 Mar 2.

Department of Medicine, Stanford University, Stanford, CA, 94305, USA.

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http://dx.doi.org/10.1186/s13073-016-0269-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4774017PMC
March 2016

Computerized Q wave dimensions in athletes and hypertrophic cardiomyopathy patients.

J Electrocardiol 2015 May-Jun;48(3):362-7. Epub 2015 Feb 14.

Stanford University Medical School, Stanford Center for Inherited Cardiovascular Diseases, Stanford University, Stanford, CA. Electronic address:

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http://dx.doi.org/10.1016/j.jelectrocard.2015.01.009DOI Listing
February 2016

Limitations of Current AHA Guidelines and Proposal of New Guidelines for the Preparticipation Examination of Athletes.

Clin J Sport Med 2015 Nov;25(6):472-7

*Division of Cardiovascular Medicine, Standford University, Palo Alto, California; and †Division of Cardiovascular Medicine, Veterans Affairs Palo Alto Medical Center, Palo Alto, California.

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http://dx.doi.org/10.1097/JSM.0000000000000203DOI Listing
November 2015

Letter by Wheeler et al Regarding Article, "Recognition and Significance of Pathological T-Wave Inversions in Athletes".

Circulation 2015 Oct;132(14):e180

Stanford Clinic for Sports Cardiology, Division of Cardiovascular Medicine, Department of Medicine, Stanford University, Stanford, CA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.016237DOI Listing
October 2015

Personalized preventive medicine: genetics and the response to regular exercise in preventive interventions.

Prog Cardiovasc Dis 2015 Jan-Feb;57(4):337-46. Epub 2014 Aug 13.

Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Stanford University, Stanford, CA, USA; Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA USA.

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http://dx.doi.org/10.1016/j.pcad.2014.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4285566PMC
March 2015

Hypertrophic cardiomyopathy: can the horse be put back in the barn?

J Am Coll Cardiol 2015 Feb;65(6):570-2

Center for Inherited Cardiovascular Disease, Stanford University, Stanford, California. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2014.12.004DOI Listing
February 2015

Physical activity and other health behaviors in adults with hypertrophic cardiomyopathy.

Am J Cardiol 2013 Apr 19;111(7):1034-9. Epub 2013 Jan 19.

Department of Internal Medicine, Division of Cardiovascular Medicine, Penn State University School of Medicine, Hershey, PA, USA.

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http://dx.doi.org/10.1016/j.amjcard.2012.12.018DOI Listing
April 2013

DNA sequencing: clinical applications of new DNA sequencing technologies.

Circulation 2012 Feb;125(7):931-44

Center for Inherited Cardiovascular Disease, Division of Cardiovascular Medicine, Stanford University School of Medicine, Falk CVRB, 300 Pasteur Dr, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.110.972828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364518PMC
February 2012

Systems biology of heart failure, challenges and hopes.

Curr Opin Cardiol 2011 Jul;26(4):314-21

Division of Cardiovascular Medicine, Stanford Hospital and Clinics, Stanford, California, USA.

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http://dx.doi.org/10.1097/HCO.0b013e328346597dDOI Listing
July 2011

Extremely elevated lipoprotein(a), combined hyperlipidemia, and premature atherosclerosis in a Chinese family.

J Clin Lipidol 2010 Nov-Dec;4(6):543-7. Epub 2010 Sep 29.

Cardiovascular Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1016/j.jacl.2010.09.002DOI Listing
June 2011

Gene coexpression network topology of cardiac development, hypertrophy, and failure.

Circ Cardiovasc Genet 2011 Feb 2;4(1):26-35. Epub 2010 Dec 2.

Department of Internal Medicine and the Division of Cardiovascular Medicine, Stanford Hospital and Clinics, and Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1161/CIRCGENETICS.110.941757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324316PMC
February 2011

Challenges in the clinical application of whole-genome sequencing.

Lancet 2010 May 29;375(9727):1749-51. Epub 2010 Apr 29.

Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

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http://dx.doi.org/10.1016/S0140-6736(10)60599-5DOI Listing
May 2010

Addition of the electrocardiogram to the preparticipation examination of college athletes.

Clin J Sport Med 2010 Mar;20(2):98-105

Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California 94304, USA.

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http://dx.doi.org/10.1097/JSM.0b013e3181d44705DOI Listing
March 2010

Mechanisms of exercise intolerance in patients with hypertrophic cardiomyopathy.

Am Heart J 2009 Sep 16;158(3):e27-34. Epub 2009 Jul 16.

Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000287030900448
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http://dx.doi.org/10.1016/j.ahj.2009.06.006DOI Listing
September 2009

Pharmacogenetics of heart failure: evidence, opportunities, and challenges for cardiovascular pharmacogenomics.

J Cardiovasc Transl Res 2008 Mar 29;1(1):25-36. Epub 2008 Jan 29.

Division of Cardiovascular Medicine, Department of Medicine, Stanford University, 300 Pasteur Drive, Falk CVRC MC 5406, Stanford, CA 94305, USA.

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http://dx.doi.org/10.1007/s12265-007-9007-8DOI Listing
March 2008

The interaction of coronary tone and cardiac fibrosis.

Curr Atheroscler Rep 2005 May;7(3):219-26

Section of Cardiology, Department of Medicine, The University of Chicago, 5841 South Maryland Avenue, MC 6088, Chicago, IL 60637, USA.

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http://link.springer.com/content/pdf/10.1007/s11883-005-0010
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http://dx.doi.org/10.1007/s11883-005-0010-8DOI Listing
May 2005

The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses.

Nat Immunol 2004 Oct 29;5(10):1052-60. Epub 2004 Aug 29.

Department of Medicine, University of California at San Francisco, San Francisco, California 94143-0451, USA.

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http://dx.doi.org/10.1038/ni1110DOI Listing
October 2004

Secondary coronary artery vasospasm promotes cardiomyopathy progression.

Am J Pathol 2004 Mar;164(3):1063-71

Department of Molecular Genetics and Cell Biology, Section of Cardiology, University of Chicago, Chicago, Illinois, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1614719PMC
http://dx.doi.org/10.1016/S0002-9440(10)63193-8DOI Listing
March 2004

Smooth muscle cell-extrinsic vascular spasm arises from cardiomyocyte degeneration in sarcoglycan-deficient cardiomyopathy.

J Clin Invest 2004 Mar;113(5):668-75

Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, Illinois 60673, USA.

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http://dx.doi.org/10.1172/JCI20410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC351323PMC
March 2004

Functional nitric oxide synthase mislocalization in cardiomyopathy.

J Mol Cell Cardiol 2004 Feb;36(2):213-23

Department of Medicine, Section of Cardiology, The University of Chicago, 5841 S. Maryland, MC6088, Rm G611, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2003.09.020DOI Listing
February 2004

Sarcoglycans in vascular smooth and striated muscle.

Trends Cardiovasc Med 2003 Aug;13(6):238-43

Department of Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1016/s1050-1738(03)00101-4DOI Listing
August 2003

Cytoskeletal defects in cardiomyopathy.

J Mol Cell Cardiol 2003 Mar;35(3):231-41

Department of Medicine, The University of Chicago, 5841 S. Maryland, MC6088, Chicago, IL, USA.

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http://dx.doi.org/10.1016/s0022-2828(03)00018-xDOI Listing
March 2003

Zeta-sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophy.

Hum Mol Genet 2002 Sep;11(18):2147-54

Department of Molecular Genetics and Cell Biology, University of Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/hmg/11.18.2147DOI Listing
September 2002

Cardiomyopathy is independent of skeletal muscle disease in muscular dystrophy.

FASEB J 2002 Jul 8;16(9):1096-8. Epub 2002 May 8.

Department of Medicine, Section of Cardiology, The University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1096/fj.01-0954fjeDOI Listing
July 2002

Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels.

J Clin Invest 2002 Jul;110(2):203-8

University of Chicago, Department of Medicine, Section of Cardiology, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1172/JCI15672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC151064PMC
July 2002