Matthew R Pincus

Matthew R Pincus

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Matthew R Pincus

Matthew R Pincus

Publications by authors named "Matthew R Pincus"

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Low Energy Conformations for S100 Binding Peptide from the Negative Regulatory Domain of p53.

Protein J 2018 12;37(6):510-517

Department of Pathology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY, 11203, USA.

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http://dx.doi.org/10.1007/s10930-018-9799-1DOI Listing
December 2018

Stability of Values for the Activities of Critical Enzymes Assayed in Serum Frozen for Prolonged Time Periods.

Ann Clin Lab Sci 2018 Sep;48(5):618-626

Division of Clinical Chemistry, Department of Pathology, SUNY Downstate Medical Center, Brooklyn, NY

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September 2018

Narcotic Analgesics and Common Drugs of Abuse: Clinical Correlations and Laboratory Assessment.

Clin Lab Med 2016 Dec;36(4):603-634

Department of Pathology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cll.2016.07.013DOI Listing
December 2016

Emerging Role of MDM2 as Target for Anti-Cancer Therapy: A Review.

Ann Clin Lab Sci 2016 Dec;46(6):627-634

Drexel University College of Medicine, Department of Surgery, Philadelphia, PA, USA

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December 2016

Ex vivo Efficacy of Anti-Cancer Drug PNC-27 in the Treatment of Patient-Derived Epithelial Ovarian Cancer.

Ann Clin Lab Sci 2015 ;45(6):650-8

Department of Pathology, SUNY Downstate Medical Center, Brooklyn, NY, USA Department of Cell Biology, SUNY Downstate Medical Center, Brooklyn, NY, USA.

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September 2016

Metastatic Small Cell Carcinoma of the Lung: An Unusual Cause of Acute Fulminant Hepatic Failure.

Fed Pract 2016 Aug;33(Suppl 5):30S-34S

, , , , , and are all resident physicians, is the chief of anatomic pathology, is co-chief of the Section of General Internal Medicine, is the chief of Medical Service, and is a critical care and pulmonary medicine physician, all at the Brooklyn Campus of the VA New York Harbor Healthcare System. Dr. Wieczorek is a clinical professor of pathology, is a professor of pathology, Dr. Blumenthal is a clinical associate professor of medicine, and Drs. Goozner and Al-Jam are assistant professors of medicine, all at SUNY Downstate Medical Center in Brooklyn.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375525PMC
August 2016

Papillary urothelial carcinoma with squamous differentiation in association with human papilloma virus: case report and literature review.

Am J Clin Exp Urol 2016 28;4(1):12-6. Epub 2016 Jan 28.

Department of Pathology, York University School of MedicineNew York, NY 10010, USA; Department of Veterans Affairs New York Harbor Healthcare SystemNew York, NY 10010, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749403PMC
April 2016

De novo large cell neuroendocrine carcinoma of the prostate, case report and literature review.

Am J Clin Exp Urol 2014 25;2(4):337-42. Epub 2014 Dec 25.

Department of Pathology, New York University School of Medicine New York, NY ; Department of New York Harbor Healthcare System, New York University School of Medicine New York, NY ; Department of Urology, New York University School of Medicine New York, NY.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297330PMC
January 2015

Tumor-targeting peptides and small molecules as anti-cancer agents to overcome drug resistance.

Curr Med Chem 2014 ;21(14):1618-30

Dept. Pathology, Box 25, 450 Clarkson Ave, BSB 4-122, Brooklyn, NY, 11203, USA.

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http://dx.doi.org/10.2174/09298673113209990223DOI Listing
December 2014

Low energy conformations for gonadotropin-releasing hormone with D- and L-amino acid substitutions for Gly 6: possible receptor-bound conformations.

Protein J 2014 Dec;33(6):575-87

Department of Pathology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY, 11203, USA,

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http://dx.doi.org/10.1007/s10930-014-9590-xDOI Listing
December 2014

The low-energy conformations of gonadotropin-releasing hormone in aqueous solution.

Protein J 2014 Dec;33(6):565-74

Department of Pathology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY, 11203, USA,

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http://dx.doi.org/10.1007/s10930-014-9589-3DOI Listing
December 2014

Beyond infectious disease: welcome to the era of population microbiology.

Clin Lab Med 2014 Dec 31;34(4):xi-xiii. Epub 2014 Oct 31.

New York University Medical Center, 550 First Avenue, New York, NY 10016, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cll.2014.09.001DOI Listing
December 2014

Comparison of glucose determinations on blood samples collected in three types of tubes.

Ann Clin Lab Sci 2013 ;43(3):278-84

Department of Pathology, SUNY Downstate Medical Center, Brooklyn, NY, 11209, USA.

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November 2013

Stability of BUN and creatinine determinations on the Siemens Advia 1800 analyzer.

J Clin Lab Anal 2013 Nov;27(6):435-7

Department of Pathology and Laboratory Medicine, NY Harbor VA Medical Center 800 Poly Place, Brooklyn, New York; Department of Pathology, SUNY Downstate Medical Center, Brooklyn, New York.

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http://dx.doi.org/10.1002/jcla.21624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807597PMC
November 2013

A peptide from a ras effector-domain blocks ras-dependent cardiac hypertrophy in myocytes.

Ann Clin Lab Sci 2009 ;39(4):351-60

Molecular Cardiology Program, NY Harbor VA Medical Center, Brooklyn, New York 11209, USA.

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September 2013

Parotid gland abscess caused by Haemophilus paraphrophilus: a case report.

Ann Clin Lab Sci 2012 ;42(4):422-3

Department of Pathology, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.

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March 2013

Stability of electrolyte determinations on the Siemens Advia 1800 analyzer.

J Clin Lab Anal 2012 Sep;26(5):372-5

Department of Pathology, SUNY Downstate Medical Center, Brooklyn, New York, NY, USA.

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http://dx.doi.org/10.1002/jcla.21533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807598PMC
September 2012

Anti-cancer peptides from ras-p21 and p53 proteins.

Curr Pharm Des 2011 ;17(25):2677-98

Department of Pathology & Laboratory Medicine, New York Harbor VA Medical Center, Brooklyn, NY 11209, USA.

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http://dx.doi.org/10.2174/138161211797416075DOI Listing
March 2012

Conformational effects of a common codon 751 polymorphism on the C-terminal domain of the xeroderma pigmentosum D protein.

J Carcinog 2009 ;8:12

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032; Division of Environmental and Occupational Health Sciences, School of Public Health, University of Illinois at Chicago, Chicago, IL 60612, USA.

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http://dx.doi.org/10.4103/1477-3163.54918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2799167PMC
July 2011

The anti-cancer peptide, PNC-27, induces tumor cell lysis as the intact peptide.

Cancer Chemother Pharmacol 2010 Jul 25;66(2):325-31. Epub 2010 Feb 25.

Department of Surgery, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.

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http://dx.doi.org/10.1007/s00280-009-1166-7DOI Listing
July 2010

Utility of desmin and a Masson's trichrome method to detect early acute myocardial infarction in autopsy tissues.

Int J Clin Exp Pathol 2009 Sep 20;3(1):98-105. Epub 2009 Sep 20.

Department of Pathology, State University of New York Downstate Medical Center, and New York Harbor Healthcare System, Brooklyn, NY 11209, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776270PMC
September 2009

Two peptides derived from ras-p21 induce either phenotypic reversion or tumor cell necrosis of ras-transformed human cancer cells.

Cancer Chemother Pharmacol 2008 Aug 8;62(3):491-8. Epub 2007 Dec 8.

Department of Pathology and Laboratory Medicine, New York Harbor VA Medical Center, 800 Poly Place, Brooklyn, NY 11209, USA.

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http://dx.doi.org/10.1007/s00280-007-0630-5DOI Listing
August 2008

IgG anti-cardiomyocyte antibodies in giant cell myocarditis.

Ann Clin Lab Sci 2008 ;38(1):83-7

Department of Pathology, SUNY Downstate Medical Center, Box 40, 450 Clarkson Avenue, Brooklyn, NY 11203, USA.

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April 2008

Conformational effects of a common codon 399 polymorphism on the BRCT1 domain of the XRCC1 protein.

Protein J 2007 Dec;26(8):541-6

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 60 Haven Avenue, B-1, New York, NY 10032, USA.

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http://dx.doi.org/10.1007/s10930-007-9095-yDOI Listing
December 2007

The dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type--but not by oncogenic--ras-p21 protein.

Front Biosci 2007 Sep 1;12:5089-97. Epub 2007 Sep 1.

Research and Development Service and Program in Molecular Cardiology, New York Harbor VA Medical Center, Brooklyn, NY 11209, USA.

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http://dx.doi.org/10.2741/2550DOI Listing
September 2007

Novel peptides from the RAS-p21 and p53 proteins for the treatment of cancer.

Cancer Ther 2007 ;5B:331-344

Department of Surgery, New York Harbor VA Medical Center, 800 Poly Place, Brooklyn, NY 11209.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2078333PMC
January 2007

Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic RAS-P21 in Xenopus oocytes.

Front Biosci 2006 Sep 1;11:2420-7. Epub 2006 Sep 1.

Molecular Cardiology, New York Harbor VA Medical Center, Brooklyn, NY 11209, USA.

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http://dx.doi.org/10.2741/1979DOI Listing
September 2006

Novel mutations of epidermal growth factor receptor in localized prostate cancer.

Front Biosci 2006 Sep 1;11:2518-25. Epub 2006 Sep 1.

Department of Urology, New York University School of Medicine, New York, NY 10016, USA.

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http://dx.doi.org/10.2741/1986DOI Listing
September 2006

Comparison of the predicted structures of loops in the ras-SOS protein bound to a single ras-p21 protein with the crystallographically determined structures in SOS bound to two ras-p21 proteins.

Protein J 2005 Aug;24(6):391-8

Department of Pathology, New York Harbor VA Medical Center, 800 Poly Place, Brooklyn, NY, 11209.

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http://dx.doi.org/10.1007/s10930-005-7593-3DOI Listing
August 2005

Specificity of inhibition of ras-p21 signal transduction by peptides from GTPase activating protein (GAP) and the son-of sevenless (SOS) ras-specific guanine nucleotide exchange protein.

Protein J 2005 May;24(4):253-8

Departments of Biology and Chemistry, Long Island University, 1 University Plaza, Brooklyn, NY, 11201, USA.

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http://dx.doi.org/10.1007/s10930-005-6723-2DOI Listing
May 2005

The role of alpha-helical structure in p53 peptides as a determinant for their mechanism of cell death: necrosis versus apoptosis.

Adv Drug Deliv Rev 2005 Feb 8;57(4):653-60. Epub 2005 Jan 8.

Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, 701 West 168th Street rm. 5-531, New York, NY 10032, USA.

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http://dx.doi.org/10.1016/j.addr.2004.10.008DOI Listing
February 2005

Effector peptides from glutathione-S-transferase-pi affect the activation of jun by jun-N-terminal kinase.

Ann Clin Lab Sci 2004 ;34(1):35-46

QRNA Corp, New York, NY, USA.

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November 2004

Computational protein chemistry of p53 and p53 peptides.

Front Biosci 2004 Sep 1;9:2778-87. Epub 2004 Sep 1.

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.2741/1435DOI Listing
September 2004

Development of new anti-cancer peptides from conformational energy analysis of the oncogenic ras-p21 protein and its complexes with target proteins.

Authors:
Matthew R Pincus

Front Biosci 2004 Sep 1;9:3486-509. Epub 2004 Sep 1.

Department of Pathology and Laboratory Medicine, New York Harbor VA Medical Center, 800 Poly Place, Brooklyn, NY 1209, USA.

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http://dx.doi.org/10.2741/1496DOI Listing
September 2004

An effector peptide from glutathione-S-transferase-pi strongly and selectively blocks mitotic signaling by oncogenic ras-p21.

Protein J 2004 Apr;23(3):235-8

Department of Pathology and Laboratory Medicine, New York Harbor VA Medical Center, Brooklyn, NY 11209, USA.

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http://dx.doi.org/10.1023/b:jopc.0000026419.54902.bbDOI Listing
April 2004

NMR solution structure of a peptide from the mdm-2 binding domain of the p53 protein that is selectively cytotoxic to cancer cells.

Biochemistry 2004 Feb;43(7):1854-61

Department of Environmental Health Sciences, Mailman School of Public Health of Columbia University, 60 Haven Avenue, New York, New York 10032, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi035718g
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http://dx.doi.org/10.1021/bi035718gDOI Listing
February 2004

A protein methyl transferase, PRMT5, selectively blocks oncogenic ras-p21 mitogenic signal transduction.

Ann Clin Lab Sci 2003 ;33(2):200-7

Department of Pathology & Laboratory Medicine, New York Harbor VA Medical Center, Brooklyn, NY 11209, USA.

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January 2004

Oncogenic and activated wild-type ras-p21 proteins induce different isoforms of protein kinase C in mitogenic signal transduction.

J Protein Chem 2003 Nov;22(7-8):625-9

Department of Pathology and Laboratory Medicine, New York Harbor VA Medical Center, 800 Poly Place, Brooklyn, NY 11209, USA.

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http://dx.doi.org/10.1023/b:jopc.0000008727.46554.9eDOI Listing
November 2003

Preferential induction of necrosis in human breast cancer cells by a p53 peptide derived from the MDM2 binding site.

Oncogene 2003 Mar;22(10):1431-44

Experimental Therapeutics Program, Division of Medical Oncology, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.

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http://dx.doi.org/10.1038/sj.onc.1206258DOI Listing
March 2003

Interactions that favor the native over the non-native disulfide bond among residues 58-72 in the oxidative folding of bovine pancreatic ribonuclease A.

Biochemistry 2002 Dec;41(50):14815-9

Department of Biochemistry, State University of New York Health Science Center, 450 Clarkson Avenue, Brooklyn 11203, USA.

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http://dx.doi.org/10.1021/bi0205350DOI Listing
December 2002

Identification of the site of inhibition of mitogenic signaling by oncogenic ras-p21 by a ras effector peptide.

J Protein Chem 2002 Jul;21(5):367-70

Department of Pathology and Laboratory Medicine, Harbor VA Medical Center, Brooklyn, NY 11209, USA.

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http://link.springer.com/content/pdf/10.1023/A:1019998403181
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http://dx.doi.org/10.1023/a:1019998403181DOI Listing
July 2002