Matthew R Hildebrandt

Matthew R Hildebrandt

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Matthew R Hildebrandt

Matthew R Hildebrandt

Publications by authors named "Matthew R Hildebrandt"

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Cytoplasmic aggregation of DDX1 in developing embryos: Early embryonic lethality associated with Ddx1 knockout.

Dev Biol 2019 Nov 19;455(2):420-433. Epub 2019 Jul 19.

Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, Alberta, T6G 1Z2, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2019.07.014DOI Listing
November 2019

Generation of infant- and pediatric-derived urinary induced pluripotent stem cells competent to form kidney organoids.

Pediatr Res 2019 Oct 19. Epub 2019 Oct 19.

Division of Nephrology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/s41390-019-0618-yDOI Listing
October 2019

The Personal Genome Project Canada: findings from whole genome sequences of the inaugural 56 participants.

CMAJ 2018 02;190(5):E126-E136

The Centre for Applied Genomics (Reuter, Walker, Thiruvahindrapuram, Whitney, Yuen, Trost, Paton, Pereira, Herbrick, Wintle, Merico, Howe, MacDonald, Lu, Nalpathamkalam, Sung, Wang, Patel, Pellecchia, J. Wei, Strug, Bell, Kellam, Mahtani, Hosseini, Fiume, Marshall, Buchanan, Scherer); Divisions of Clinical Pharmacology and Toxicology (I. Cohn), or Clinical, and Metabolic Genetics (Sondheimer, Weksberg, Shuman, Bowdin, Meyn, Monfared), The Hospital for Sick Children; Departments of Paediatrics (Sondheimer, R. Cohn) and Molecular Genetics (Yuen, Weksberg, Shuman, R. Cohn, Ellis, Meyn), University of Toronto; Deep Genomics Inc. (Merico); Department of Psychiatry (Bassett), University Health Network and Centre for Addiction and Mental Health, University of Toronto; Li Ka Shing Knowledge Institute (Bombard), St. Michael's Hospital; Institute of Health Policy, Management and Evaluation (Bombard), University of Toronto; Centre for Genetic Medicine (Stavropoulos, Bowdin, Ray, Monfared); Molecular Genetics Laboratory (Stavropoulos, Ray, Marshall), Division of Genome Diagnostics, Paediatric Laboratory Medicine; Developmental and Stem Cell Biology (Hildebrandt, W. Wei, Romm, Pasceri, Ellis); Ted Rogers Cardiac Genome Clinic (Hosseini); Cytogenetics Laboratory (Joseph-George), Division of Genome Diagnostics, Paediatric Laboratory Medicine, The Hospital for Sick Children; Departments of Biochemistry and Laboratory Medicine, and Pathobiology (Keeley), University of Toronto; DNAstack (Cook, Fiume); McLaughlin Centre (Lee, Scherer), University of Toronto; Medcan Health Management Inc. (Davies, Hazell); Dalla Lana School of Public Health (Szego), Department of Family and Community Medicine, and The Joint Centre for Bioethics, University of Toronto; Centre for Clinical Ethics (Szego), St. Joseph's Health Centre, Toronto, Ont.

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http://dx.doi.org/10.1503/cmaj.171151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798982PMC
February 2018

Role for RIF1-interacting partner DDX1 in BLM recruitment to DNA double-strand breaks.

DNA Repair (Amst) 2017 07 13;55:47-63. Epub 2017 May 13.

Department of Oncology, Cross Cancer Institute, University of Alberta, 11560 University Avenue, Edmonton Alberta T6G 1Z2, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2017.05.001DOI Listing
July 2017

DEAD Box 1 Facilitates Removal of RNA and Homologous Recombination at DNA Double-Strand Breaks.

Mol Cell Biol 2016 11 28;36(22):2794-2810. Epub 2016 Oct 28.

Department of Oncology, University of Alberta, Cross Cancer Institute, Edmonton, Alberta, Canada

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http://dx.doi.org/10.1128/MCB.00415-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086521PMC
November 2016

Loss of the Drosophila melanogaster DEAD box protein Ddx1 leads to reduced size and aberrant gametogenesis.

Dev Biol 2015 Nov 1;407(2):232-45. Epub 2015 Oct 1.

Departments of Oncology University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, T6G 1Z2, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2015.09.012DOI Listing
November 2015

Ddx1 knockout results in transgenerational wild-type lethality in mice.

Sci Rep 2015 Apr 24;5:9829. Epub 2015 Apr 24.

Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta T6G 1Z2, Canada.

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http://dx.doi.org/10.1038/srep09829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4408975PMC
April 2015