Publications by authors named "Matthew R Bersi"

21Publications

Genetic ablation of serotonin receptor 2B improves aortic valve hemodynamics of Notch1 heterozygous mice in a high-cholesterol diet model.

Authors:
J Ethan Joll Cynthia R Clark Christine S Peters Michael A Raddatz Matthew R Bersi W David Merryman

PLoS One 2020 25;15(11):e0238407. Epub 2020 Nov 25.

Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States of America.

View Article and Find Full Text PDF
December 2020

Inhibition of focal adhesion kinase increases myofibril viscosity in cardiac myocytes.

Authors:
Nilay Taneja Matthew R Bersi Megan L Rasmussen Vivian Gama W David Merryman Dylan T Burnette

Cytoskeleton (Hoboken) 2020 09 9;77(9):342-350. Epub 2020 Sep 9.

Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.

View Article and Find Full Text PDF
September 2020

Computational Modeling Predicts Immuno-Mechanical Mechanisms of Maladaptive Aortic Remodeling in Hypertension.

Authors:
Marcos Latorre Matthew R Bersi Jay D Humphrey

Int J Eng Sci 2019 Aug 31;141:35-46. Epub 2019 May 31.

Department of Biomedical Engineering Yale University, New Haven, CT, USA.

View Article and Find Full Text PDF
August 2019

Multimodality Imaging-Based Characterization of Regional Material Properties in a Murine Model of Aortic Dissection.

Authors:
Matthew R Bersi Víctor A Acosta Santamaría Karl Marback Paolo Di Achille Evan H Phillips Craig J Goergen Jay D Humphrey Stéphane Avril

Sci Rep 2020 06 8;10(1):9244. Epub 2020 Jun 8.

Mines Saint-Etienne, University of Lyon, University Jean Monnet, INSERM, Saint-Etienne, France.

View Article and Find Full Text PDF
June 2020

Macrophages Promote Aortic Valve Cell Calcification and Alter STAT3 Splicing.

Authors:
Michael A Raddatz Tessa Huffstater Matthew R Bersi Bradley I Reinfeld Matthew Z Madden Sabrina E Booton W Kimryn Rathmell Jeffrey C Rathmell Brian R Lindman Meena S Madhur W David Merryman

Arterioscler Thromb Vasc Biol 2020 06 16;40(6):e153-e165. Epub 2020 Apr 16.

Department of Biomedical Engineering (M.A.R., T.H., M.R.B., S.E.B., W.D.M.), Vanderbilt University, Nashville, TN.

View Article and Find Full Text PDF
June 2020

Precise Tuning of Cortical Contractility Regulates Cell Shape during Cytokinesis.

Authors:
Nilay Taneja Matthew R Bersi Sophie M Baillargeon Aidan M Fenix James A Cooper Ryoma Ohi Vivian Gama W David Merryman Dylan T Burnette

Cell Rep 2020 04;31(1):107477

Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

View Article and Find Full Text PDF
April 2020

Chronic mTOR activation induces a degradative smooth muscle cell phenotype.

Authors:
Guangxin Li Mo Wang Alexander W Caulk Nicholas A Cilfone Sharvari Gujja Lingfeng Qin Pei-Yu Chen Zehua Chen Sameh Yousef Yang Jiao Changshun He Bo Jiang Arina Korneva Matthew R Bersi Guilin Wang Xinran Liu Sameet Mehta Arnar Geirsson Jeffrey R Gulcher Thomas W Chittenden Michael Simons Jay D Humphrey George Tellides

J Clin Invest 2020 03;130(3):1233-1251

Department of Surgery, Yale School of Medicine, New Haven, Connecticut, USA.

View Article and Find Full Text PDF
March 2020

A detailed mechanical and microstructural analysis of ovine tricuspid valve leaflets.

Authors:
William D Meador Mrudang Mathur Gabriella P Sugerman Tomasz Jazwiec Marcin Malinowski Matthew R Bersi Tomasz A Timek Manuel K Rausch

Acta Biomater 2020 01 22;102:100-113. Epub 2019 Nov 22.

Department of Biomedical Engineering, The University of Texas at Austin, Austin, TX 78705, USA; Department of Mechanical Engineering, The University of Texas at Austin, Austin, TX 78705, USA; Department of Aerospace Engineering and Engineering Mechanics, The University of Texas at Austin, Austin, TX 78705, USA. Electronic address:

View Article and Find Full Text PDF
January 2020

The regional-dependent biaxial behavior of young and aged mouse skin: A detailed histomechanical characterization, residual strain analysis, and constitutive model.

Authors:
William D Meador Gabriella P Sugerman Hannah M Story Ashley W Seifert Matthew R Bersi Adrian B Tepole Manuel K Rausch

Acta Biomater 2020 01 12;101:403-413. Epub 2019 Oct 12.

Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA; Department of Aerospace Engineering and Engineering Mechanics, University of Texas at Austin, Austin, TX, USA; Oden Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, USA. Electronic address:

View Article and Find Full Text PDF
January 2020

Cadherin-11 blockade reduces inflammation-driven fibrotic remodeling and improves outcomes after myocardial infarction.

Authors:
Alison K Schroer Matthew R Bersi Cynthia R Clark Qinkun Zhang Lehanna H Sanders Antonis K Hatzopoulos Thomas L Force Susan M Majka Hind Lal W David Merryman

JCI Insight 2019 09 19;4(18). Epub 2019 Sep 19.

Department of Biomedical Engineering.

View Article and Find Full Text PDF
September 2019

Co-localization of microstructural damage and excessive mechanical strain at aortic branches in angiotensin-II-infused mice.

Authors:
Lydia Aslanidou Mauro Ferraro Goran Lovric Matthew R Bersi Jay D Humphrey Patrick Segers Bram Trachet Nikos Stergiopulos

Biomech Model Mechanobiol 2020 Feb 4;19(1):81-97. Epub 2019 Jul 4.

Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

View Article and Find Full Text PDF
February 2020

Cadherin-11 as a regulator of valve myofibroblast mechanobiology.

Authors:
Meghan A Bowler Matthew R Bersi Larisa M Ryzhova Rachel J Jerrell Aron Parekh W David Merryman

Am J Physiol Heart Circ Physiol 2018 12 25;315(6):H1614-H1626. Epub 2018 Oct 25.

Department of Biomedical Engineering, Vanderbilt University , Nashville, Tennessee.

View Article and Find Full Text PDF
December 2018

LNK deficiency promotes acute aortic dissection and rupture.

Authors:
Fanny Laroumanie Arina Korneva Matthew R Bersi Matthew R Alexander Liang Xiao Xue Zhong Justin P Van Beusecum Yuhan Chen Mohamed A Saleh William G McMaster Kyle A Gavulic Bethany L Dale Shilin Zhao Yan Guo Yu Shyr Daniel S Perrien Nancy J Cox John A Curci Jay D Humphrey Meena S Madhur

JCI Insight 2018 10 18;3(20). Epub 2018 Oct 18.

Division of Clinical Pharmacology, Vanderbilt University Medical Center (VUMC), Nashville, Tennessee, USA.

View Article and Find Full Text PDF
October 2018

Local variations in material and structural properties characterize murine thoracic aortic aneurysm mechanics.

Authors:
Matthew R Bersi Chiara Bellini Jay D Humphrey Stéphane Avril

Biomech Model Mechanobiol 2019 Feb 24;18(1):203-218. Epub 2018 Sep 24.

INSERM U1059, SAINBIOSE, CIS-EMSE, Mines Saint-Etienne, University of Lyon, 42023, Saint Etienne, France.

View Article and Find Full Text PDF
February 2019

Data-driven Modeling of Hemodynamics and its Role on Thrombus Size and Shape in Aortic Dissections.

Authors:
Alireza Yazdani He Li Matthew R Bersi Paolo Di Achille Joseph Insley Jay D Humphrey George Em Karniadakis

Sci Rep 2018 02 6;8(1):2515. Epub 2018 Feb 6.

Division of Applied Mathematics, Brown University, Providence, RI, 02912, USA.

View Article and Find Full Text PDF
February 2018

Correlation of Wall Microstructure and Heterogeneous Distributions of Strain in Evolving Murine Abdominal Aortic Aneurysms.

Authors:
John S Wilson Matthew R Bersi Guangxin Li Jay D Humphrey

Cardiovasc Eng Technol 2017 06 4;8(2):193-204. Epub 2017 Apr 4.

Department of Biomedical Engineering, Yale University, New Haven, CT, USA.

View Article and Find Full Text PDF
June 2017

Deficient Circumferential Growth Is the Primary Determinant of Aortic Obstruction Attributable to Partial Elastin Deficiency.

Authors:
Yang Jiao Guangxin Li Arina Korneva Alexander W Caulk Lingfeng Qin Matthew R Bersi Qingle Li Wei Li Robert P Mecham Jay D Humphrey George Tellides

Arterioscler Thromb Vasc Biol 2017 05 2;37(5):930-941. Epub 2017 Mar 2.

From the Department of Surgery, Yale University School of Medicine, New Haven, CT (Y.J., G.L., L.Q., Q.L., W.L., G.T.); Department of Vascular Surgery, Peking University People's Hospital, Beijing, People's Republic of China (Y.J., Q.L., W.L.); Department of Vascular Surgery, The First Hospital of China Medical University, Shenyang, People's Republic of China (G.L.); Department of Biomedical Engineering, Yale University, New Haven, CT (A.K., A.W.C., M.R.B., J.D.H.); Department of Cell Biology, Washington University School of Medicine, St Louis, MO (R.P.M.); Interdepartmental Program in Vascular Biology and Therapeutics, Yale University School of Medicine (J.D.H., G.T.); and Veterans Affairs Connecticut Healthcare System, West Haven (G.T.).

View Article and Find Full Text PDF
May 2017

Multi-Modality Imaging Enables Detailed Hemodynamic Simulations in Dissecting Aneurysms in Mice.

Authors:
Evan H Phillips Paolo Di Achille Matthew R Bersi Jay D Humphrey Craig J Goergen

IEEE Trans Med Imaging 2017 06 6;36(6):1297-1305. Epub 2017 Feb 6.

View Article and Find Full Text PDF
June 2017

Novel Methodology for Characterizing Regional Variations in the Material Properties of Murine Aortas.

Authors:
Matthew R Bersi Chiara Bellini Paolo Di Achille Jay D Humphrey Katia Genovese Stéphane Avril

J Biomech Eng 2016 07;138(7)

View Article and Find Full Text PDF
July 2016

Long-Term Functional Efficacy of a Novel Electrospun Poly(Glycerol Sebacate)-Based Arterial Graft in Mice.

Authors:
Ramak Khosravi Cameron A Best Robert A Allen Chelsea E T Stowell Ekene Onwuka Jennifer J Zhuang Yong-Ung Lee Tai Yi Matthew R Bersi Toshiharu Shinoka Jay D Humphrey Yadong Wang Christopher K Breuer

Ann Biomed Eng 2016 08 21;44(8):2402-2416. Epub 2016 Jan 21.

Tissue Engineering Program and Surgical Research, Nationwide Children's Hospital, 575 Children's Crossroads, Research III - WB4151, Columbus, OH, 43215, USA.

View Article and Find Full Text PDF
August 2016

Characterization of evolving biomechanical properties of tissue engineered vascular grafts in the arterial circulation.

Authors:
Brooks V Udelsman Ramak Khosravi Kristin S Miller Ethan W Dean Matthew R Bersi Kevin Rocco Tai Yi Jay D Humphrey Christopher K Breuer

J Biomech 2014 Jun 15;47(9):2070-9. Epub 2014 Mar 15.

Nationwide Children׳s Hospital, 700 Children׳s Drive-WB4151, Columbus, OH 43205, USA. Electronic address:

View Article and Find Full Text PDF
June 2014