Matthew Meyerson

Matthew Meyerson

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A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma.

Cancer Res 2019 May 28;79(9):2352-2366. Epub 2019 Feb 28.

Cancer Program, The Broad Institute of M.I.T. and Harvard, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-2711DOI Listing
May 2019

Identification and Characterization of Oncogenic Mutations in Lung Adenocarcinoma.

Mol Cancer Res 2019 04 11;17(4):1002-1012. Epub 2019 Jan 11.

Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.

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http://mcr.aacrjournals.org/lookup/doi/10.1158/1541-7786.MCR
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http://dx.doi.org/10.1158/1541-7786.MCR-18-0316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445719PMC
April 2019

Circulating Tumor DNA Provides a Sneak Peek into Treatment Responses in Non-Small Cell Lung Cancer.

Cancer Res 2019 Mar;79(6):1038-1040

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-0231DOI Listing
March 2019

Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.

Cell 2019 Feb 31;176(5):998-1013.e16. Epub 2019 Jan 31.

David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.12.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691977PMC
February 2019

Distinct pathways affected by menin versus MLL1/MLL2 in MLL-rearranged acute myeloid leukemia.

Exp Hematol 2019 01 10;69:37-42. Epub 2018 Oct 10.

Department of Pediatrics, University of Colorado, Denver/Anschutz Medical Campus. Aurora, CO, USA; Department of Pharmacology, University of Colorado, Denver/Anschutz Medical Campus. Aurora, CO, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X183085
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http://dx.doi.org/10.1016/j.exphem.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472707PMC
January 2019

The Amount of Bifidobacterium Genus in Colorectal Carcinoma Tissue in Relation to Tumor Characteristics and Clinical Outcome.

Am J Pathol 2018 12 20;188(12):2839-2852. Epub 2018 Sep 20.

Department of Oncologic Pathology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts; Broad Institute of MIT and Harvard, Cambridge, Massachusetts; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Program in MPE Molecular Pathological Epidemiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2018.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284552PMC
December 2018

Autophosphorylation of the carboxyl-terminal domain is not required for oncogenic transformation by lung-cancer derived EGFR mutants.

Int J Cancer 2018 08 5;143(3):679-685. Epub 2018 Mar 5.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, 02115.

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http://dx.doi.org/10.1002/ijc.31332DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033109PMC
August 2018

Genomic and Functional Approaches to Understanding Cancer Aneuploidy.

Cancer Cell 2018 04 2;33(4):676-689.e3. Epub 2018 Apr 2.

Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA; Cancer Program, Broad Institute, 415 Main Street, Cambridge, MA 02142, USA; Department of Pathology, Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028190PMC
April 2018

Mechanistic Insights into Transmissible Cancers of Mammals.

Cancer Cell 2018 04;33(4):543-544

Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, MA, USA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.03.019DOI Listing
April 2018

Landscapes of childhood tumours.

Nature 2018 03;555(7696):316-317

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http://dx.doi.org/10.1038/d41586-018-01648-4DOI Listing
March 2018

Exon 14 Mutation Encodes an Actionable Therapeutic Target in Lung Adenocarcinoma.

Cancer Res 2017 08 18;77(16):4498-4505. Epub 2017 May 18.

Division of Hematology and Oncology, Department of Medicine and Helen Diller Family Comprehensive Cancer Center University of California, San Francisco, California.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004099PMC
August 2017

Emerging Concepts and Technologies for the Discovery of Microorganisms Involved in Human Disease.

Annu Rev Pathol 2017 Jan 5;12:217-244. Epub 2016 Dec 5.

Research Division, Joslin Diabetes Center, Boston, Massachusetts 02215; email:

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http://dx.doi.org/10.1146/annurev-pathol-012615-044305DOI Listing
January 2017

Insertions and Deletions Target Lineage-Defining Genes in Human Cancers.

Cell 2017 01 12;168(3):460-472.e14. Epub 2017 Jan 12.

Cancer Program, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.12.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5564321PMC
January 2017

Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets.

Cancer Biol Ther 2016 12 1;17(12):1274-1281. Epub 2016 Nov 1.

b Department of Medical Oncology & Center for Cancer Genome Discovery , Dana-Farber Cancer Institute, Harvard Medical School , Boston , MA , USA.

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http://dx.doi.org/10.1080/15384047.2016.1250986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5199165PMC
December 2016

Copy number alterations unmasked as enhancer hijackers.

Nat Genet 2016 12;49(1):5-6

Dana-Farber Cancer Institute, the Broad Institute of Harvard and MIT, and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3754DOI Listing
December 2016

Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia.

Cancer Cell 2016 Nov 3;30(5):750-763. Epub 2016 Nov 3.

Department of Medical Oncology, Dana-Farber Cancer Institute, Dana 540, 44 Binney Street, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02141, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127278PMC
November 2016

Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting.

Cancer Discov 2016 08 3;6(8):914-29. Epub 2016 Jun 3.

Dana-Farber Cancer Institute, Boston, Massachusetts. Broad Institute of Harvard and MIT, Cambridge, Massachusetts. Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Harvard Medical School, Boston, Massachusetts. Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-16-0154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4972686PMC
August 2016

VariantBam: filtering and profiling of next-generational sequencing data using region-specific rules.

Bioinformatics 2016 07 26;32(13):2029-31. Epub 2016 Feb 26.

The Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920121PMC
July 2016

Identification of an "Exceptional Responder" Cell Line to MEK1 Inhibition: Clinical Implications for MEK-Targeted Therapy.

Mol Cancer Res 2016 Feb 18;14(2):207-15. Epub 2015 Nov 18.

Broad Institute of Harvard and MIT, Cambridge, Massachusetts. Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Pathology, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1541-7786.MCR-15-0321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755909PMC
February 2016

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers.

Nat Genet 2016 Feb 14;48(2):176-82. Epub 2015 Dec 14.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3470DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857881PMC
February 2016

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma.

Authors:
W Marston Linehan Paul T Spellman Christopher J Ricketts Chad J Creighton Suzanne S Fei Caleb Davis David A Wheeler Bradley A Murray Laura Schmidt Cathy D Vocke Myron Peto Abu Amar M Al Mamun Eve Shinbrot Anurag Sethi Samira Brooks W Kimryn Rathmell Angela N Brooks Katherine A Hoadley A Gordon Robertson Denise Brooks Reanne Bowlby Sara Sadeghi Hui Shen Daniel J Weisenberger Moiz Bootwalla Stephen B Baylin Peter W Laird Andrew D Cherniack Gordon Saksena Scott Haake Jun Li Han Liang Yiling Lu Gordon B Mills Rehan Akbani Mark D M Leiserson Benjamin J Raphael Pavana Anur Donald Bottaro Laurence Albiges Nandita Barnabas Toni K Choueiri Bogdan Czerniak Andrew K Godwin A Ari Hakimi Thai H Ho James Hsieh Michael Ittmann William Y Kim Bhavani Krishnan Maria J Merino Kenna R Mills Shaw Victor E Reuter Ed Reznik Carl S Shelley Brian Shuch Sabina Signoretti Ramaprasad Srinivasan Pheroze Tamboli George Thomas Satish Tickoo Kenneth Burnett Daniel Crain Johanna Gardner Kevin Lau David Mallery Scott Morris Joseph D Paulauskis Robert J Penny Candace Shelton W Troy Shelton Mark Sherman Eric Thompson Peggy Yena Melissa T Avedon Jay Bowen Julie M Gastier-Foster Mark Gerken Kristen M Leraas Tara M Lichtenberg Nilsa C Ramirez Tracie Santos Lisa Wise Erik Zmuda John A Demchok Ina Felau Carolyn M Hutter Margi Sheth Heidi J Sofia Roy Tarnuzzer Zhining Wang Liming Yang Jean C Zenklusen Jiashan Zhang Brenda Ayala Julien Baboud Sudha Chudamani Jia Liu Laxmi Lolla Rashi Naresh Todd Pihl Qiang Sun Yunhu Wan Ye Wu Adrian Ally Miruna Balasundaram Saianand Balu Rameen Beroukhim Tom Bodenheimer Christian Buhay Yaron S N Butterfield Rebecca Carlsen Scott L Carter Hsu Chao Eric Chuah Amanda Clarke Kyle R Covington Mahmoud Dahdouli Ninad Dewal Noreen Dhalla Harsha V Doddapaneni Jennifer A Drummond Stacey B Gabriel Richard A Gibbs Ranabir Guin Walker Hale Alicia Hawes D Neil Hayes Robert A Holt Alan P Hoyle Stuart R Jefferys Steven J M Jones Corbin D Jones Divya Kalra Christie Kovar Lora Lewis Jie Li Yussanne Ma Marco A Marra Michael Mayo Shaowu Meng Matthew Meyerson Piotr A Mieczkowski Richard A Moore Donna Morton Lisle E Mose Andrew J Mungall Donna Muzny Joel S Parker Charles M Perou Jeffrey Roach Jacqueline E Schein Steven E Schumacher Yan Shi Janae V Simons Payal Sipahimalani Tara Skelly Matthew G Soloway Carrie Sougnez Angela Tam Donghui Tan Nina Thiessen Umadevi Veluvolu Min Wang Matthew D Wilkerson Tina Wong Junyuan Wu Liu Xi Jane Zhou Jason Bedford Fengju Chen Yao Fu Mark Gerstein David Haussler Katayoon Kasaian Phillip Lai Shiyun Ling Amie Radenbaugh David Van Den Berg John N Weinstein Jingchun Zhu Monique Albert Iakovina Alexopoulou Jeremiah J Andersen J Todd Auman John Bartlett Sheldon Bastacky Julie Bergsten Michael L Blute Lori Boice Roni J Bollag Jeff Boyd Erik Castle Ying-Bei Chen John C Cheville Erin Curley Benjamin Davies April DeVolk Rajiv Dhir Laura Dike John Eckman Jay Engel Jodi Harr Ronald Hrebinko Mei Huang Lori Huelsenbeck-Dill Mary Iacocca Bruce Jacobs Michael Lobis Jodi K Maranchie Scott McMeekin Jerome Myers Joel Nelson Jeremy Parfitt Anil Parwani Nicholas Petrelli Brenda Rabeno Somak Roy Andrew L Salner Joel Slaton Melissa Stanton R Houston Thompson Leigh Thorne Kelinda Tucker Paul M Weinberger Cynthia Winemiller Leigh Anne Zach Rosemary Zuna

Characterization of DDR2 Inhibitors for the Treatment of DDR2 Mutated Nonsmall Cell Lung Cancer.

ACS Chem Biol 2015 Dec 25;10(12):2687-96. Epub 2015 Sep 25.

Department of Medical Oncology, Dana-Farber Cancer Institute , Boston, Massachusetts, United States.

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http://pubs.acs.org/doi/10.1021/acschembio.5b00655
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http://dx.doi.org/10.1021/acschembio.5b00655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685943PMC
December 2015

Chromothripsis from DNA damage in micronuclei.

Nature 2015 Jun 27;522(7555):179-84. Epub 2015 May 27.

1] Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [2] Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA [3] Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA [4] Howard Hughes Medical Institute, Chevy Chase, Maryland 20815, USA.

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http://dx.doi.org/10.1038/nature14493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742237PMC
June 2015

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

Authors:
Daniel J Brat Roel G W Verhaak Kenneth D Aldape W K Alfred Yung Sofie R Salama Lee A D Cooper Esther Rheinbay C Ryan Miller Mark Vitucci Olena Morozova A Gordon Robertson Houtan Noushmehr Peter W Laird Andrew D Cherniack Rehan Akbani Jason T Huse Giovanni Ciriello Laila M Poisson Jill S Barnholtz-Sloan Mitchel S Berger Cameron Brennan Rivka R Colen Howard Colman Adam E Flanders Caterina Giannini Mia Grifford Antonio Iavarone Rajan Jain Isaac Joseph Jaegil Kim Katayoon Kasaian Tom Mikkelsen Bradley A Murray Brian Patrick O'Neill Lior Pachter Donald W Parsons Carrie Sougnez Erik P Sulman Scott R Vandenberg Erwin G Van Meir Andreas von Deimling Hailei Zhang Daniel Crain Kevin Lau David Mallery Scott Morris Joseph Paulauskis Robert Penny Troy Shelton Mark Sherman Peggy Yena Aaron Black Jay Bowen Katie Dicostanzo Julie Gastier-Foster Kristen M Leraas Tara M Lichtenberg Christopher R Pierson Nilsa C Ramirez Cynthia Taylor Stephanie Weaver Lisa Wise Erik Zmuda Tanja Davidsen John A Demchok Greg Eley Martin L Ferguson Carolyn M Hutter Kenna R Mills Shaw Bradley A Ozenberger Margi Sheth Heidi J Sofia Roy Tarnuzzer Zhining Wang Liming Yang Jean Claude Zenklusen Brenda Ayala Julien Baboud Sudha Chudamani Mark A Jensen Jia Liu Todd Pihl Rohini Raman Yunhu Wan Ye Wu Adrian Ally J Todd Auman Miruna Balasundaram Saianand Balu Stephen B Baylin Rameen Beroukhim Moiz S Bootwalla Reanne Bowlby Christopher A Bristow Denise Brooks Yaron Butterfield Rebecca Carlsen Scott Carter Lynda Chin Andy Chu Eric Chuah Kristian Cibulskis Amanda Clarke Simon G Coetzee Noreen Dhalla Tim Fennell Sheila Fisher Stacey Gabriel Gad Getz Richard Gibbs Ranabir Guin Angela Hadjipanayis D Neil Hayes Toshinori Hinoue Katherine Hoadley Robert A Holt Alan P Hoyle Stuart R Jefferys Steven Jones Corbin D Jones Raju Kucherlapati Phillip H Lai Eric Lander Semin Lee Lee Lichtenstein Yussanne Ma Dennis T Maglinte Harshad S Mahadeshwar Marco A Marra Michael Mayo Shaowu Meng Matthew L Meyerson Piotr A Mieczkowski Richard A Moore Lisle E Mose Andrew J Mungall Angeliki Pantazi Michael Parfenov Peter J Park Joel S Parker Charles M Perou Alexei Protopopov Xiaojia Ren Jeffrey Roach Thaís S Sabedot Jacqueline Schein Steven E Schumacher Jonathan G Seidman Sahil Seth Hui Shen Janae V Simons Payal Sipahimalani Matthew G Soloway Xingzhi Song Huandong Sun Barbara Tabak Angela Tam Donghui Tan Jiabin Tang Nina Thiessen Timothy Triche David J Van Den Berg Umadevi Veluvolu Scot Waring Daniel J Weisenberger Matthew D Wilkerson Tina Wong Junyuan Wu Liu Xi Andrew W Xu Lixing Yang Travis I Zack Jianhua Zhang B Arman Aksoy Harindra Arachchi Chris Benz Brady Bernard Daniel Carlin Juok Cho Daniel DiCara Scott Frazer Gregory N Fuller JianJiong Gao Nils Gehlenborg David Haussler David I Heiman Lisa Iype Anders Jacobsen Zhenlin Ju Sol Katzman Hoon Kim Theo Knijnenburg Richard Bailey Kreisberg Michael S Lawrence William Lee Kalle Leinonen Pei Lin Shiyun Ling Wenbin Liu Yingchun Liu Yuexin Liu Yiling Lu Gordon Mills Sam Ng Michael S Noble Evan Paull Arvind Rao Sheila Reynolds Gordon Saksena Zack Sanborn Chris Sander Nikolaus Schultz Yasin Senbabaoglu Ronglai Shen Ilya Shmulevich Rileen Sinha Josh Stuart S Onur Sumer Yichao Sun Natalie Tasman Barry S Taylor Doug Voet Nils Weinhold John N Weinstein Da Yang Kosuke Yoshihara Siyuan Zheng Wei Zhang Lihua Zou Ty Abel Sara Sadeghi Mark L Cohen Jenny Eschbacher Eyas M Hattab Aditya Raghunathan Matthew J Schniederjan Dina Aziz Gene Barnett Wendi Barrett Darell D Bigner Lori Boice Cathy Brewer Chiara Calatozzolo Benito Campos Carlos Gilberto Carlotti Timothy A Chan Lucia Cuppini Erin Curley Stefania Cuzzubbo Karen Devine Francesco DiMeco Rebecca Duell J Bradley Elder Ashley Fehrenbach Gaetano Finocchiaro William Friedman Jordonna Fulop Johanna Gardner Beth Hermes Christel Herold-Mende Christine Jungk Ady Kendler Norman L Lehman Eric Lipp Ouida Liu Randy Mandt Mary McGraw Roger Mclendon Christopher McPherson Luciano Neder Phuong Nguyen Ardene Noss Raffaele Nunziata Quinn T Ostrom Cheryl Palmer Alessandro Perin Bianca Pollo Alexander Potapov Olga Potapova W Kimryn Rathmell Daniil Rotin Lisa Scarpace Cathy Schilero Kelly Senecal Kristen Shimmel Vsevolod Shurkhay Suzanne Sifri Rosy Singh Andrew E Sloan Kathy Smolenski Susan M Staugaitis Ruth Steele Leigh Thorne Daniela P C Tirapelli Andreas Unterberg Mahitha Vallurupalli Yun Wang Ronald Warnick Felicia Williams Yingli Wolinsky Sue Bell Mara Rosenberg Chip Stewart Franklin Huang Jonna L Grimsby Amie J Radenbaugh Jianan Zhang
June 2015

Updated Frequency of EGFR and KRAS Mutations in NonSmall-Cell Lung Cancer in Latin America: The Latin-American Consortium for the Investigation of Lung Cancer (CLICaP).

J Thorac Oncol 2015 May;10(5):838-43

*Thoracic Oncology Clinic and Experimental Oncology Laboratory, Instituto Nacional de Cancerologia de México, México D.F., México; †Clinical and Translational Oncology Group, Fundación Santa Fe de Bogotá, Bogotá, Colombia; ‡Department of Oncology, Alexander Fleming Institute, Buenos Aires, Argentina; §Department of Clinical Oncology, Instituto de Enfermedades Neoplásicas, Perú; ‖Oncología Médica, Hospital San Juan de Dios, San José, Costa Rica; ¶Cátedra de Farmacología, Facultad de Farmacia y Bioquimica, Universidad de Buenos, Fundación Investigar, Buenos Aires, Argentina; #Instituto Oncológico Nacional, Ancón, Panamá; **Broad Institute of Harvard, Massachusetts Institute of Technology, Cambridge, Massachusetts; ††Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts; ‡‡Centro Médico Nacional 20 de Noviembre de México, ISSSTE, México D.F., México; §§Departament of Medicine, Hospital de Clínicas UdelaR, Montevideo, Uruguay; and ‖‖Clínica Del Hospital Británico de Buenos Aires, Ciudad Autónoma de Buenos Aires.

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http://dx.doi.org/10.1097/JTO.0000000000000481DOI Listing
May 2015

Dynamic epigenetic regulation by menin during pancreatic islet tumor formation.

Mol Cancer Res 2015 Apr 23;13(4):689-98. Epub 2014 Dec 23.

Department of Medical Oncology, Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts. Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts. Cancer program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0457DOI Listing
April 2015

Oncotator: cancer variant annotation tool.

Hum Mutat 2015 Apr 16;36(4):E2423-9. Epub 2015 Mar 16.

Cancer Program, Broad Institute, Cambridge, MA 02142, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Pathology, Harvard Medical School, Boston, MA 02115, USA; Cancer Center and Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://doi.wiley.com/10.1002/humu.22771
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http://dx.doi.org/10.1002/humu.22771DOI Listing
April 2015

Pugh et al. reply.

Nature 2015 Apr;520(7547):E12-4

1] Department of Medical Oncology and Center for Cancer Genome Discovery, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [2] Cancer Program, Broad Institute, Cambridge, Massachusetts, 02142, USA.

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http://dx.doi.org/10.1038/nature14266DOI Listing
April 2015

Calibrating genomic and allelic coverage bias in single-cell sequencing.

Nat Commun 2015 Apr 16;6:6822. Epub 2015 Apr 16.

Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, USA.

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http://dx.doi.org/10.1038/ncomms7822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4922254PMC
April 2015

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution.

Genome Res 2015 Mar 3;25(3):316-27. Epub 2015 Feb 3.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA;

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http://dx.doi.org/10.1101/gr.180612.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352879PMC
March 2015

BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers.

Nucleic Acids Res 2015 Feb 26;43(3):e19. Epub 2014 Nov 26.

Center for Cancer Genome Discovery and Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA Department of Pathology, Brigham and Women's Hospital, Boston, MA 02215, USA

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http://dx.doi.org/10.1093/nar/gku1211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4330340PMC
February 2015

Malawi polyomavirus is a prevalent human virus that interacts with known tumor suppressors.

J Virol 2015 Jan 15;89(1):857-62. Epub 2014 Oct 15.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA Program in Virology, Harvard University Graduate School of Arts and Sciences, Division of Medical Sciences, Boston, Massachusetts, USA Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA

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http://dx.doi.org/10.1128/JVI.02328-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301141PMC
January 2015

Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma.

Cancer Res 2015 Jan 8;75(2):264-9. Epub 2014 Dec 8.

Department of Cardiothoracic Surgery, NYU Langone Medical Center, New York, New York.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1008DOI Listing
January 2015

Genetic modifiers of EGFR dependence in non-small cell lung cancer.

Proc Natl Acad Sci U S A 2014 Dec 15;111(52):18661-6. Epub 2014 Dec 15.

Broad Institute of Harvard and MIT, Cambridge, MA 02142; Departments of Pathology and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115; and

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http://dx.doi.org/10.1073/pnas.1412228112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284598PMC
December 2014