Publications by authors named "Matthew J Walter"

62Publications

Haploinsufficiency of multiple del(5q) genes induce B cell abnormalities in mice.

Leuk Res 2020 Sep 23;96:106428. Epub 2020 Jul 23.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, United States; Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri, United States. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2020.106428DOI Listing
September 2020

Genetics of progression from MDS to secondary leukemia.

Blood 2020 Jul;136(1):50-60

Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO; and.

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http://dx.doi.org/10.1182/blood.2019000942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7332895PMC
July 2020

Mutation Clearance after Transplantation for Myelodysplastic Syndrome.

N Engl J Med 2018 12;379(24):2380

Washington University School of Medicine, St. Louis, MO

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http://dx.doi.org/10.1056/NEJMc1813470DOI Listing
December 2018

Immune Escape of Relapsed AML Cells after Allogeneic Transplantation.

N Engl J Med 2018 12 31;379(24):2330-2341. Epub 2018 Oct 31.

From the Division of Oncology, Department of Internal Medicine (M.J.C., A.A.P., M.P.R., C.A.M., E.C., N.M.H., L.D.W., J.S.W., S.E.H., D.C.L., M.J.W., P.W., T.J.L., J.F.D.), the McDonnell Genome Institute (A.A.P., C.A.M., M.O., C.C.F., R.S.F., L.D.W., T.J.L.), the Department of Pathology and Immunology (E.J.D., J.E.P.), and the Division of Biostatistics (J.D.B.), Washington University in St. Louis, St. Louis; the Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN (J.M.K.); the Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH (R.K.W.); and the Center for Cancer Research, Massachusetts General Hospital, Boston (T.A.G.).

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http://www.nejm.org/doi/10.1056/NEJMoa1808777
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http://dx.doi.org/10.1056/NEJMoa1808777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322675PMC
December 2018

Mutation Clearance after Transplantation for Myelodysplastic Syndrome.

N Engl J Med 2018 Sep;379(11):1028-1041

From the Department of Pathology and Immunology (E.J.D.), the Department of Medicine, Division of Oncology (M.A.J., C.A.M., N.E., J.S., K.E., J.R., S.E.H., K.B., L.D.W., M.J.C., I.P., J.S.W., G.L.U., D.C.L., J.F.D., P.W., T.J.L., M.J.W.), the McDonnell Genome Institute (G.S.C., C.A.M., H.A., R.S.F., C.C.F., M.O.), the Department of Medicine, Division of Hospital Medicine (R.S.), and Siteman Biostatistics Shared Resource, Siteman Cancer Center (K.T.), Washington University School of Medicine in St. Louis, St. Louis; and Massachusetts General Hospital Cancer Center, Boston (T.A.G.).

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http://www.nejm.org/doi/10.1056/NEJMoa1804714
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http://dx.doi.org/10.1056/NEJMoa1804714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309244PMC
September 2018

Systematic Analysis of Splice-Site-Creating Mutations in Cancer.

Cell Rep 2018 04;23(1):270-281.e3

Department of Medicine, Washington University in St. Louis, St. Louis, MO 63110, USA; McDonnell Genome Institute, Washington University in St. Louis, St. Louis, MO 63108, USA; Division of Oncology, Washington University in St. Louis, St. Louis, MO 63110, USA; Department of Genetics, Washington University in St. Louis, St. Louis, MO 63110, USA; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.03.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055527PMC
April 2018

CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression.

Cell 2017 02 16;168(5):801-816.e13. Epub 2017 Feb 16.

Section of Stem Cell Biology, Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; The McDonnell Genome Institute, Washington University, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328582PMC
February 2017

Knockdown of HSPA9 induces TP53-dependent apoptosis in human hematopoietic progenitor cells.

PLoS One 2017 8;12(2):e0170470. Epub 2017 Feb 8.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0170470PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5298293PMC
August 2017

Antecedent CHIP in CML?

Authors:
Matthew J Walter

Blood 2017 01;129(1):3-4

WASHINGTON UNIVERSITY SCHOOL OF MEDICINE.

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http://dx.doi.org/10.1182/blood-2016-11-746842DOI Listing
January 2017

TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes.

N Engl J Med 2016 11;375(21):2023-2036

the Department of Internal Medicine, Division of Oncology (J.S.W., L.D.W., G.L.U., A.G., M.H.T., I.P., R.R., T.A.F., K.E.S.-G., R.V., S.T.O., C.N.A., A.F.C., M.A.S., M.A.J., S.E.H., K.L., M.R.J., M.J.W., P.W., D.C.L., J.F.D., T.J.L.), and the Division of Biostatistics (J.D.B.), and the Department of Pathology and Immunology (E.J.D., B.T., Y.-S.L.), Washington University School of Medicine, and McDonnell Genome Institute, Washington University in St. Louis (A.A.P., C.A.M., C.C.F., M.O., R.S.F., R.K.W., L.D.W., T.J.L.) - both in St. Louis; the Departments of Internal Medicine (A.H., N.K., M.J.S., W.S.) and Pharmacy (R.W.K.), University of Chicago, Chicago; and the Department of Internal Medicine (T.A.G.), Massachusetts General Hospital, Boston.

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http://dx.doi.org/10.1056/NEJMoa1605949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217532PMC
November 2016

Splicing factor gene mutations in hematologic malignancies.

Blood 2017 03 9;129(10):1260-1269. Epub 2016 Dec 9.

Massachusetts General Hospital Cancer Center, Boston, MA.

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http://dx.doi.org/10.1182/blood-2016-10-692400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5345729PMC
March 2017

Implications of Tumor Clonal Heterogeneity in the Era of Next-Generation Sequencing.

Trends Cancer 2015 Dec 25;1(4):231-241. Epub 2015 Nov 25.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St Louis, MO, USA; Alvin J. Siteman Cancer Center, Washington University School of Medicine, St Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.trecan.2015.10.006DOI Listing
December 2015

What came first: MDS or AML?

Authors:
Matthew J Walter

Blood 2015 Feb;125(9):1357-8

WASHINGTON UNIVERSITY.

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http://dx.doi.org/10.1182/blood-2015-01-621193DOI Listing
February 2015

Reduced levels of Hspa9 attenuate Stat5 activation in mouse B cells.

Exp Hematol 2015 Apr 27;43(4):319-30.e10. Epub 2014 Dec 27.

Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA; Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA; Siteman Cancer Center, Washington University School of Medicine, St. Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2014.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4375022PMC
April 2015

Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Nat Med 2014 Dec 19;20(12):1472-8. Epub 2014 Oct 19.

1] The Genome Institute, Washington University in St. Louis, St. Louis, Missouri, USA. [2] Department of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA. [3] Department of Genetics, Washington University in St. Louis, St. Louis, Missouri, USA. [4] Siteman Cancer Center, Washington University in St. Louis, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1038/nm.3733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313872PMC
December 2014

SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution.

PLoS Comput Biol 2014 Aug 7;10(8):e1003665. Epub 2014 Aug 7.

The Genome Institute, Washington University, St. Louis, Missouri, United States of America; Department of Internal Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Genetics, Washington University, St. Louis, Missouri, United States of America; Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1003665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125065PMC
August 2014

Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing.

PLoS Genet 2014 Jul 10;10(7):e1004462. Epub 2014 Jul 10.

Department of Internal Medicine, Division of Oncology, Washington University, St. Louis, Missouri, United States of America; Siteman Cancer Center, Washington University, St. Louis, Missouri, United States of America; Department of Pathology and Immunology, Washington University, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004462DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091781PMC
July 2014

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia.

Cancer Cell 2014 Mar 6;25(3):379-92. Epub 2014 Mar 6.

The Genome Institute, Washington University, St. Louis, MO 63110, USA; Division of Oncology, Section of Stem Cell Biology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.01.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983786PMC
March 2014

Acquired copy number alterations of miRNA genes in acute myeloid leukemia are uncommon.

Blood 2013 Oct 5;122(15):e44-51. Epub 2013 Sep 5.

Jane Anne Nohl Division of Hematology, Department of Medicine, University of Southern California, Los Angeles, CA;

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http://dx.doi.org/10.1182/blood-2013-03-488007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795465PMC
October 2013

Emerging importance of mutational analysis in myelodysplastic syndrome and acute myelogenous leukemia.

Biol Blood Marrow Transplant 2013 Jan;19(1 Suppl):S33-7

Fred Hutchinson Cancer Research Center, Seattle, Washington; University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1016/j.bbmt.2012.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897298PMC
January 2013

Detection of copy number alterations in acute myeloid leukemia and myelodysplastic syndromes.

Expert Rev Mol Diagn 2012 Apr;12(3):253-64

Department of Internal Medicine, Washington University School of Medicine, Division of Oncology, Stem Cell Biology Section, Campus Box 8007, 660 South Euclid Avenue, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1586/erm.12.18DOI Listing
April 2012

Genetics of myelodysplastic syndromes: new insights.

Hematology Am Soc Hematol Educ Program 2011 ;2011:543-9

Washington University, St Louis, MO 63110, USA.

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http://dx.doi.org/10.1182/asheducation-2011.1.543DOI Listing
April 2012

Knockdown of Hspa9, a del(5q31.2) gene, results in a decrease in hematopoietic progenitors in mice.

Blood 2011 Feb 1;117(5):1530-9. Epub 2010 Dec 1.

Department of Medicine, Division of Oncology, Washington University School of Medicine, 660 South Euclid Ave., St Louis, MO 63110, USA.

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http://dx.doi.org/10.1182/blood-2010-06-293167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056590PMC
February 2011

Therapy related acute myeloid leukemia in breast cancer survivors, a population-based study.

Breast Cancer Res Treat 2009 Dec 26;118(3):593-8. Epub 2009 Mar 26.

Division of Oncology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8007, Saint Louis, MO 63110, USA.

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http://link.springer.com/10.1007/s10549-009-0376-3
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http://dx.doi.org/10.1007/s10549-009-0376-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400139PMC
December 2009

Expression of a bcr-1 isoform of RARalpha-PML does not affect the penetrance of acute promyelocytic leukemia or the acquisition of an interstitial deletion on mouse chromosome 2.

Blood 2007 Feb 28;109(3):1237-40. Epub 2006 Sep 28.

Department of Medicine, Division of Oncology, Siteman Cancer Center, Washington University School of Medicine, St Louis, MO 63110-1093, USA.

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http://dx.doi.org/10.1182/blood-2006-07-037465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1785146PMC
February 2007

Reduced PU.1 expression causes myeloid progenitor expansion and increased leukemia penetrance in mice expressing PML-RARalpha.

Proc Natl Acad Sci U S A 2005 Aug 19;102(35):12513-8. Epub 2005 Aug 19.

Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1073/pnas.0504247102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1188022PMC
August 2005

Expression profiling of murine acute promyelocytic leukemia cells reveals multiple model-dependent progression signatures.

Mol Cell Biol 2004 Dec;24(24):10882-93

Division of Oncology, Section of Stem Cell Biology, Campus Box 8007, 660 South Euclid Ave., St. Louis, MO 63110-1093, USA.

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http://dx.doi.org/10.1128/MCB.24.24.10882-10893.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC533966PMC
December 2004

Adaptive immunity cooperates with liposomal all-trans-retinoic acid (ATRA) to facilitate long-term molecular remissions in mice with acute promyelocytic leukemia.

Proc Natl Acad Sci U S A 2002 Jul 20;99(14):9468-73. Epub 2002 Jun 20.

Division of Oncology, Department of Medicine, Siteman Cancer Center, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8007, St. Louis, MO 63110-1093, USA.

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http://dx.doi.org/10.1073/pnas.132657799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123164PMC
July 2002