Matthew J Sweet

Matthew J Sweet

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SCIMP is a universal Toll-like receptor adaptor in macrophages.

J Leukoc Biol 2020 02 29;107(2):251-262. Epub 2019 Aug 29.

Institute for Molecular Bioscience (IMB) and IMB Centre for Inflammation and Disease Research, The University of Queensland, Brisbane, Queensland, Australia.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/JLB.2MA0819-
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http://dx.doi.org/10.1002/JLB.2MA0819-138RRDOI Listing
February 2020

Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2.

Cell Rep 2020 Feb;30(8):2712-2728.e8

Institute for Molecular Bioscience (IMB), The University of Queensland, Brisbane, Queensland 4072, Australia; IMB Centre for Inflammation and Disease Research and Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Queensland 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.02.007DOI Listing
February 2020

Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic type 2 inflammation.

Br J Pharmacol 2019 10 17;176(19):3775-3790. Epub 2019 Aug 17.

Centre for Inflammation and Disease Research, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1111/bph.14768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780048PMC
October 2019

Variation in hemolysin A expression between uropathogenic isolates determines NLRP3-dependent -independent macrophage cell death and host colonization.

FASEB J 2019 06 14;33(6):7437-7450. Epub 2019 Mar 14.

Centre for Inflammation and Disease Research, Institute for Molecular Bioscience (IMB), The University of Queensland, Brisbane, Queensland, Australia.

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https://www.fasebj.org/doi/10.1096/fj.201802100R
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http://dx.doi.org/10.1096/fj.201802100RDOI Listing
June 2019

Regulation of hemolysin in uropathogenic Escherichia coli fine-tunes killing of human macrophages.

Virulence 2018 12;9(1):967-980

a Institute for Molecular Bioscience (IMB), IMB Centre for Inflammation and Disease Research, and the Australian Infectious Diseases Research Centre, The University of Queensland , QLD , Australia.

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http://dx.doi.org/10.1080/21505594.2018.1465786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989160PMC
December 2018

Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion.

Cell Rep 2018 08;24(6):1425-1433

Institute for Molecular Bioscience (IMB), and IMB Centre for Inflammation and Disease Research, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.07.027DOI Listing
August 2018

Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps.

Sci Immunol 2018 08;3(26)

Institute for Molecular Bioscience (IMB) and IMB Centre for Inflammation and Disease Research, University of Queensland, St Lucia Brisbane 4072, Queensland, Australia.

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http://dx.doi.org/10.1126/sciimmunol.aar6676DOI Listing
August 2018

Lysine Deacetylases and Regulated Glycolysis in Macrophages.

Trends Immunol 2018 06 19;39(6):473-488. Epub 2018 Mar 19.

Institute for Molecular Bioscience (IMB), IMB Centre for Inflammation and Disease Research, and Australian Infectious Diseases Research Centre, University of Queensland, Brisbane, QLD 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.it.2018.02.009DOI Listing
June 2018

pTRAPs: Transmembrane adaptors in innate immune signaling.

J Leukoc Biol 2018 Mar 30. Epub 2018 Mar 30.

Institute for Molecular Bioscience (IMB), IMB Centre for Inflammation and Disease Research and Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1002/JLB.2RI1117-474RDOI Listing
March 2018

Group A streptococcal pharyngitis: Immune responses involved in bacterial clearance and GAS-associated immunopathologies.

J Leukoc Biol 2018 02 29;103(2):193-213. Epub 2017 Dec 29.

School of Chemistry and Molecular Biosciences, Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Australia.

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http://doi.wiley.com/10.1189/jlb.4MR0617-227RR
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http://dx.doi.org/10.1189/jlb.4MR0617-227RRDOI Listing
February 2018

For when bacterial infections persist: Toll-like receptor-inducible direct antimicrobial pathways in macrophages.

J Leukoc Biol 2018 01 3;103(1):35-51. Epub 2018 Jan 3.

Institute for Molecular Bioscience (IMB) and IMB Centre for Inflammation and Disease Research, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1002/JLB.4RI0917-358RDOI Listing
January 2018

In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis.

Tissue Barriers 2017 10 7;5(4):e1345353. Epub 2017 Jul 7.

a Division of Cell Biology and Molecular Medicine , Institute for Molecular Bioscience, The University of Queensland , St. Lucia, Brisbane , Queensland , Australia.

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http://dx.doi.org/10.1080/21688370.2017.1345353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788429PMC
October 2017

Genome-Wide Discovery of Genes Required for Capsule Production by Uropathogenic .

mBio 2017 10 24;8(5). Epub 2017 Oct 24.

School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia

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http://dx.doi.org/10.1128/mBio.01558-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654933PMC
October 2017

Development of SH2 probes and pull-down assays to detect pathogen-induced, site-specific tyrosine phosphorylation of the TLR adaptor SCIMP.

Immunol Cell Biol 2017 07 14;95(6):564-570. Epub 2017 Mar 14.

Institute for Molecular Bioscience (IMB) and IMB Centre for Inflammation and Disease Research, The University of Queensland, Brisbane, Queensland, Australia.

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http://doi.wiley.com/10.1038/icb.2017.10
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http://dx.doi.org/10.1038/icb.2017.10DOI Listing
July 2017

Small GTPase Rab8a-recruited Phosphatidylinositol 3-Kinase γ Regulates Signaling and Cytokine Outputs from Endosomal Toll-like Receptors.

J Biol Chem 2017 03 27;292(11):4411-4422. Epub 2017 Jan 27.

From the Institute for Molecular Bioscience (IMB) and IMB Centre for Inflammation and Disease Research, University of Queensland, Brisbane, Queensland 4072, Australia and

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http://www.jbc.org/lookup/doi/10.1074/jbc.M116.766337
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http://dx.doi.org/10.1074/jbc.M116.766337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5377761PMC
March 2017

The toll-like receptor 3 pathway in homeostasis, responses to injury and wound repair.

Semin Cell Dev Biol 2017 01 20;61:22-30. Epub 2016 Aug 20.

Institute for Molecular Bioscience (IMB), The University of Queensland, Brisbane, Qld 4072, Australia; IMB Centre for Inflammation and Disease Research, The University of Queensland, Brisbane, Qld 4072, Australia; Australian Infectious Disease Research Centre, The University of Queensland, Brisbane, Qld 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2016.08.014DOI Listing
January 2017

An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice.

J Pharmacol Exp Ther 2017 Jan 8;360(1):140-151. Epub 2016 Nov 8.

Institute for Molecular Bioscience (IMB), IMB Centre for Inflammation and Disease Research, and Australian Research Council Centre of Excellence in Advanced Molecular Imaging, The University of Queensland, Brisbane, Queensland, Australia

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http://dx.doi.org/10.1124/jpet.116.236711DOI Listing
January 2017

Co-transcriptomic Analysis by RNA Sequencing to Simultaneously Measure Regulated Gene Expression in Host and Bacterial Pathogen.

Methods Mol Biol 2016 ;1390:145-58

Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia.

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http://dx.doi.org/10.1007/978-1-4939-3335-8_10DOI Listing
October 2016

The E3 ubiquitin ligase RNF144B is LPS-inducible in human, but not mouse, macrophages and promotes inducible IL-1β expression.

J Leukoc Biol 2016 07 27;100(1):155-61. Epub 2016 Jan 27.

Institute for Molecular Bioscience (IMB), The University of Queensland, Brisbane, Queensland, Australia; IMB Centre for Inflammation and Disease Research, The University of Queensland, Brisbane, Queensland, Australia; Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Queensland, Australia; and

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http://doi.wiley.com/10.1189/jlb.2AB0815-339R
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http://dx.doi.org/10.1189/jlb.2AB0815-339RDOI Listing
July 2016

TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target.

J Leukoc Biol 2016 07 9;100(1):27-45. Epub 2016 May 9.

School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, Australia; Institute for Molecular Bioscience, Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Queensland, Australia;

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http://dx.doi.org/10.1189/jlb.2RI1115-531RDOI Listing
July 2016

Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages.

FASEB J 2016 05 2;30(5):1901-12. Epub 2016 Feb 2.

Institute for Molecular Bioscience (IMB), The University of Queensland, Brisbane, Australia; IMB Centre for Inflammation and Disease Research, The University of Queensland, Brisbane, Australia; Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Australia;

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http://dx.doi.org/10.1096/fj.201500061DOI Listing
May 2016

The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists.

Eur J Immunol 2016 Apr 1;46(4):1004-10. Epub 2016 Feb 1.

Institute for Molecular Bioscience and Centre for Inflammation and Disease Research, The University of Queensland, St Lucia, Australia.

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http://dx.doi.org/10.1002/eji.201545943DOI Listing
April 2016

Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.

Sci Rep 2016 Apr 20;6:24575. Epub 2016 Apr 20.

Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.

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http://dx.doi.org/10.1038/srep24575DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837355PMC
April 2016

Uropathogenic Escherichia coli Engages CD14-Dependent Signaling to Enable Bladder-Macrophage-Dependent Control of Acute Urinary Tract Infection.

J Infect Dis 2016 Feb 30;213(4):659-68. Epub 2015 Aug 30.

Menzies Health Institute Queensland, Griffith University, Gold Coast School of Medical Science, Griffith University, Gold Coast Division of Infectious Diseases, School of Medicine, University of Alabama at Birmingham.

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http://dx.doi.org/10.1093/infdis/jiv424DOI Listing
February 2016

Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat Arthritis.

J Pharmacol Exp Ther 2016 Feb 10;356(2):387-96. Epub 2015 Dec 10.

Centre for Inflammation and Disease Research, The Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia (R.J.L., A.I., T.J.F., A.C., P.G., R.C.R., M.J.S., D.P.F.); Centre for Kidney Disease Research, Translational Research Institute, The University of Queensland, Department of Medicine at the Princes Alexandra Hospital, Australia (D.A.V.);

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http://dx.doi.org/10.1124/jpet.115.229328DOI Listing
February 2016

Using the MCoTI-II Cyclotide Scaffold To Design a Stable Cyclic Peptide Antagonist of SET, a Protein Overexpressed in Human Cancer.

Biochemistry 2016 Jan 6;55(2):396-405. Epub 2016 Jan 6.

Institute for Molecular Bioscience, The University of Queensland , Brisbane, Queensland Australia , 4072.

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http://pubs.acs.org/doi/10.1021/acs.biochem.5b00529
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http://dx.doi.org/10.1021/acs.biochem.5b00529DOI Listing
January 2016

Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases.

Clin Transl Immunology 2016 Jan 29;5(1):e62. Epub 2016 Jan 29.

Institute for Molecular Bioscience, The University of Queensland, St Lucia, Queensland, Australia; IMB Centre for Inflammation and Disease Research, The University of Queensland, St Lucia, Queensland, Australia; Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, Queensland, Australia.

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http://dx.doi.org/10.1038/cti.2015.46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735065PMC
January 2016

Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL isoforms, reveals new insights into necroptotic cell death.

Biosci Rep 2015 Dec 24;36(1):e00291. Epub 2015 Dec 24.

Department of Chemistry and Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, SI-1000, Ljubljana, Slovenia

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http://dx.doi.org/10.1042/BSR20150246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725247PMC
December 2015

Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages.

Antimicrob Agents Chemother 2015 Dec 28;60(3):1521-9. Epub 2015 Dec 28.

Institute for Molecular Bioscience, IMB Centre for Inflammation and Disease Research and Australian Infectious Diseases Research Centre, The University of Queensland, Brisbane, Queensland, Australia

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http://aac.asm.org/content/early/2015/12/15/AAC.01876-15.ful
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http://aac.asm.org/content/60/3/1521.full.pdf
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http://aac.asm.org/lookup/doi/10.1128/AAC.01876-15
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http://dx.doi.org/10.1128/AAC.01876-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775968PMC
December 2015

Innate immune perturbations, accumulating DAMPs and inflammasome dysregulation: A ticking time bomb in ageing.

Ageing Res Rev 2015 Nov 25;24(Pt A):40-53. Epub 2015 Feb 25.

Institute for Molecular Bioscience, The University of Queensland, St. Lucia, Qld, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2015.02.005DOI Listing
November 2015

HMGB1 binds to activated platelets via the receptor for advanced glycation end products and is present in platelet rich human coronary artery thrombi.

Thromb Haemost 2015 Nov 23;114(5):994-1003. Epub 2015 Jul 23.

PD Dr. Ingo Ahrens, Heart Center, University of Freiburg, Cardiology and Angiology I, Hugstetter Str. 55, 79106 Freiburg, Germany, E-mail:

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http://dx.doi.org/10.1160/TH14-12-1073DOI Listing
November 2015

The role of H4 flagella in Escherichia coli ST131 virulence.

Sci Rep 2015 Nov 9;5:16149. Epub 2015 Nov 9.

School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/srep16149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4637896PMC
November 2015

TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes.

Immunol Cell Biol 2015 Oct 25;93(9):771-9. Epub 2015 Aug 25.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/icb.2015.77DOI Listing
October 2015

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury.

Fibrogenesis Tissue Repair 2015 15;8:19. Epub 2015 Oct 15.

Centre for Liver Disease Research, School of Medicine, The University of Queensland, Translational Research Institute, 37 Kent St, Brisbane, 4102 Australia.

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http://dx.doi.org/10.1186/s13069-015-0036-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4606475PMC
October 2015

Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.

J Immunol 2015 Aug 26;195(3):1233-41. Epub 2015 Jun 26.

School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane 4072, Queensland, Australia; Institute for Molecular Bioscience, The University of Queensland, Brisbane 4072, Queensland, Australia

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http://dx.doi.org/10.4049/jimmunol.1402859DOI Listing
August 2015

The co-transcriptome of uropathogenic Escherichia coli-infected mouse macrophages reveals new insights into host-pathogen interactions.

Cell Microbiol 2015 May 24;17(5):730-46. Epub 2015 Jan 24.

Division of Biological and Environmental Sciences and Engineering, Division of Computer, Electrical and Mathematical Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Kingdom of Saudi Arabia; Division of Medical Genetics, Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, USA.

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http://doi.wiley.com/10.1111/cmi.12397
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http://dx.doi.org/10.1111/cmi.12397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950338PMC
May 2015

Senescent human hepatocytes express a unique secretory phenotype and promote macrophage migration.

World J Gastroenterol 2014 Dec;20(47):17851-62

Katharine M Irvine, Richard Skoien, Michelle Melino, Andrew D Clouston, Elizabeth E Powell, Centre for Liver Disease Research, School of Medicine, The University of Queensland, Translational Research Institute, Brisbane 4102, Australia.

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http://dx.doi.org/10.3748/wjg.v20.i47.17851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273135PMC
December 2014

Receptor-interacting protein kinase 4 and interferon regulatory factor 6 function as a signaling axis to regulate keratinocyte differentiation.

J Biol Chem 2014 Nov 22;289(45):31077-87. Epub 2014 Sep 22.

From the Oral Health Cooperative Research Centre, Melbourne Dental School, and Bio21 Institute, and Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria 3010, Australia and

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http://dx.doi.org/10.1074/jbc.M114.589382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223312PMC
November 2014

Interferon regulatory factor 6 differentially regulates Toll-like receptor 2-dependent chemokine gene expression in epithelial cells.

J Biol Chem 2014 Jul 28;289(28):19758-68. Epub 2014 May 28.

From the Oral Health Cooperative Research Centre, Melbourne Dental School, and Bio21 Institute, and Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Victoria 3010, Australia, and

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http://dx.doi.org/10.1074/jbc.M114.584540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094085PMC
July 2014

Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling.

Nat Commun 2014 Jul 15;5:4407. Epub 2014 Jul 15.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1038/ncomms5407DOI Listing
July 2014

The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge.

Cell Rep 2014 Jul 17;8(2):570-82. Epub 2014 Jul 17.

Institute for Molecular Bioscience, The University of Queensland, St Lucia 4072, Australia; Australian Infectious Disease Research Centre, The University of Queensland, St Lucia 4072, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.06.028DOI Listing
July 2014

Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis.

Cancer Med 2014 Jun 19;3(3):500-13. Epub 2014 Mar 19.

Inflammation Biology Group, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, 4029, Australia.

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http://dx.doi.org/10.1002/cam4.229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101741PMC
June 2014

Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4.

Eur J Immunol 2014 May 7;44(5):1480-90. Epub 2014 Mar 7.

The University of Queensland Diamantina Institute, The University of Queensland, Translational Research Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1002/eji.201343959DOI Listing
May 2014

Towards selective lysophospholipid GPCR modulators.

Trends Pharmacol Sci 2014 May 16;35(5):219-26. Epub 2014 Apr 16.

Division of Molecular and Cell Biology, The University of Queensland, Institute for Molecular Bioscience, St Lucia, Brisbane, QLD 4072, Australia.

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http://dx.doi.org/10.1016/j.tips.2014.03.004DOI Listing
May 2014

Protective role for Toll-like receptor-9 in the development of atherosclerosis in apolipoprotein E-deficient mice.

Arterioscler Thromb Vasc Biol 2014 Mar 16;34(3):516-25. Epub 2014 Jan 16.

From the Department of Cell Biology & Atherosclerosis (C.K., Y.C.C., C.H., I.A., T.S.K., C.T., A.B., K.P., A.A.) and Department of Diabetic Complications (C.K., T.A., K.J.-D.), Heart and Diabetes Institute, Melbourne, Victoria, Australia; Department of Cardiology and Angiology I, Heart Centre Freiburg University, Freiburg, Germany (I.A.); Molecular Cell Biology Division, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia (M.J.S.); Laboratory of Host Defense, WPI Immunology Frontier Research Centre, Osaka University, Osaka, Japan (S.A.); and Department of Immunology, Monash University, Melbourne, Victoria, Australia (A.B., K.P., A.A.).

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.113.302407
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http://dx.doi.org/10.1161/ATVBAHA.113.302407DOI Listing
March 2014

The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins.

Acta Crystallogr D Biol Crystallogr 2013 Dec 19;69(Pt 12):2420-30. Epub 2013 Nov 19.

School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.

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https://espace.library.uq.edu.au/view/UQ:312289/UQ312289_Sup
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http://scripts.iucr.org/cgi-bin/paper?S0907444913022385
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http://dx.doi.org/10.1107/S0907444913022385DOI Listing
December 2013

An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation.

Immunobiology 2013 Nov 15;218(11):1345-53. Epub 2013 Jul 15.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Qld 4072, Australia; Australian Infectious Disease Research Centre, The University of Queensland, Brisbane, Qld 4072, Australia.

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http://dx.doi.org/10.1016/j.imbio.2013.07.001DOI Listing
November 2013

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 Oct 28;69(Pt 10):1167-70. Epub 2013 Sep 28.

School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, QLD 4072, Australia.

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http://dx.doi.org/10.1107/S1744309113024408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792682PMC
October 2013

An antioxidant role for catecholate siderophores in Salmonella.

Biochem J 2013 Sep;454(3):543-9

School of Chemistry and Molecular Biosciences, Australian Infectious Diseases Research Centre, University of Queensland, St Lucia 4072, QLD, Australia.

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http://dx.doi.org/10.1042/BJ20121771DOI Listing
September 2013

Crystallization and X-ray diffraction analysis of the N-terminal domain of the Toll-like receptor signalling adaptor protein TRIF/TICAM-1.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2013 Jul 28;69(Pt 7):766-70. Epub 2013 Jun 28.

School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1107/S174430911301419XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702321PMC
July 2013

Differences in the repertoire, regulation and function of Toll-like Receptors and inflammasome-forming Nod-like Receptors between human and mouse.

Curr Opin Microbiol 2013 Jun 26;16(3):303-10. Epub 2013 Mar 26.

The University of Queensland, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, Brisbane, Qld 4072, Australia.

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http://dx.doi.org/10.1016/j.mib.2013.03.002DOI Listing
June 2013

Towards isozyme-selective HDAC inhibitors for interrogating disease.

Curr Top Med Chem 2012 ;12(14):1479-99

Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Qld 4072, Australia.

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http://dx.doi.org/10.2174/156802612802652420DOI Listing
May 2013

The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized.

Acta Crystallogr D Biol Crystallogr 2013 May 11;69(Pt 5):774-84. Epub 2013 Apr 11.

Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1107/S0907444913001558DOI Listing
May 2013

Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C.

Liver Int 2013 Apr 13;33(4):569-79. Epub 2012 Dec 13.

Centre for Liver Disease Research, School of Medicine, The University of Queensland, Princess Alexandra Hospital, Brisbane, Qld, Australia.

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http://dx.doi.org/10.1111/liv.12050DOI Listing
April 2013

Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection.

Curr Opin Microbiol 2013 Feb 8;16(1):100-7. Epub 2013 Feb 8.

School of Medical Sciences, Centre for Medicine and Oral Health, Griffith University, Southport, Australia.

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https://espace.library.uq.edu.au/view/UQ:297220/UQ297220OA.p
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http://linkinghub.elsevier.com/retrieve/pii/S136952741300008
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http://dx.doi.org/10.1016/j.mib.2013.01.005DOI Listing
February 2013

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction.

Immunobiology 2012 Dec 27;217(12):1325-9. Epub 2012 Jul 27.

Institute for Molecular Bioscience, University of Queensland, St Lucia 4072, Australia.

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http://dx.doi.org/10.1016/j.imbio.2012.07.020DOI Listing
December 2012

The mammalian PYHIN gene family: phylogeny, evolution and expression.

BMC Evol Biol 2012 Aug 7;12:140. Epub 2012 Aug 7.

The University of Queensland, School of Chemistry and Molecular Biosciences, Brisbane, Qld 4072, Australia.

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http://dx.doi.org/10.1186/1471-2148-12-140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458909PMC
August 2012

The mammalian DUF59 protein Fam96a forms two distinct types of domain-swapped dimer.

Acta Crystallogr D Biol Crystallogr 2012 Jun 17;68(Pt 6):637-48. Epub 2012 May 17.

Institute for Molecular Bioscience, Division of Chemistry and Structural Biology, University of Queensland, Brisbane, Queensland 4072, Australia.

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http://scripts.iucr.org/cgi-bin/paper?S0907444912006592
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http://dx.doi.org/10.1107/S0907444912006592DOI Listing
June 2012

Copper redistribution in murine macrophages in response to Salmonella infection.

Biochem J 2012 May;444(1):51-7

School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Brisbane, Australia.

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http://dx.doi.org/10.1042/BJ20112180DOI Listing
May 2012

LPS-induced cytokine production in human monocytes and macrophages.

Crit Rev Immunol 2011 ;31(5):379-446

Department of Internal Medicine, Rheumatology, University of Leipzig, Liebigstr. 21, 04103 Leipzig, Germany.

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http://dx.doi.org/10.1615/critrevimmunol.v31.i5.20DOI Listing
April 2012

Macrophage secretory products induce an inflammatory phenotype in hepatocytes.

World J Gastroenterol 2012 Apr;18(15):1732-44

Centre for Liver Disease Research, School of Medicine, The University of Queensland, Princess Alexandra Hospital, Brisbane 4102, Queensland, Australia.

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http://dx.doi.org/10.3748/wjg.v18.i15.1732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332286PMC
April 2012

HDAC inhibitors: modulating leukocyte differentiation, survival, proliferation and inflammation.

Immunol Cell Biol 2012 Jan 25;90(1):14-22. Epub 2011 Oct 25.

The University of Queensland, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/icb.2011.88DOI Listing
January 2012

Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides.

J Biol Chem 2011 Oct 26;286(42):36932-43. Epub 2011 Aug 26.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M111.264424
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http://dx.doi.org/10.1074/jbc.M111.264424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3196123PMC
October 2011

Histone deacetylases as regulators of inflammation and immunity.

Trends Immunol 2011 Jul 12;32(7):335-43. Epub 2011 May 12.

The University of Queensland, Institute for Molecular Bioscience and Australian Infectious Diseases Research Centre, Queensland 4072, Australia.

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http://dx.doi.org/10.1016/j.it.2011.04.001DOI Listing
July 2011

B cells do not take up bacterial DNA: an essential role for antigen in exposure of DNA to toll-like receptor-9.

Immunol Cell Biol 2011 May 5;89(4):517-25. Epub 2010 Oct 5.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1038/icb.2010.112DOI Listing
May 2011

The immunostimulatory activity of phosphorothioate CpG oligonucleotides is affected by distal sequence changes.

Mol Immunol 2011 Apr 16;48(8):1027-34. Epub 2011 Feb 16.

The University of Queensland, Institute for Molecular Bioscience, Qld 4072, Australia.

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http://dx.doi.org/10.1016/j.molimm.2011.01.011DOI Listing
April 2011

Inhibitors selective for HDAC6 in enzymes and cells.

Bioorg Med Chem Lett 2010 Dec 12;20(23):7067-70. Epub 2010 Oct 12.

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1016/j.bmcl.2010.09.100DOI Listing
December 2010

Dead cells certainly do matter, particularly when they can speak from the grave.

Authors:
Matthew J Sweet

J Leukoc Biol 2010 Dec;88(6):1065-1066

The University of Queensland, Institute for Molecular Bioscience, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1189/jlb.0810443DOI Listing
December 2010

Development and characterization of new inhibitors of the human and mouse hematopoietic prostaglandin D(2) synthases.

J Med Chem 2010 Aug;53(15):5536-48

Institute for Molecular Bioscience, The University of Queensland, Queensland, Australia.

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http://dx.doi.org/10.1021/jm100194aDOI Listing
August 2010

Experimental and bioinformatic characterisation of the promoter region of the Marfan syndrome gene, FBN1.

Genomics 2009 Oct 30;94(4):233-40. Epub 2009 Jun 30.

The University of Edinburgh, The Roslin Institute and Royal (Dick) School of Veterinary Studies, Roslin, Midlothian EH25 9PS, UK.

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http://dx.doi.org/10.1016/j.ygeno.2009.06.005DOI Listing
October 2009

Histone deacetylase inhibitors in inflammatory disease.

Curr Top Med Chem 2009 ;9(3):309-19

Institute for Molecular Bioscience, The University of Queensland, Qld 4072, Australia.

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http://dx.doi.org/10.2174/156802609788085250DOI Listing
June 2009

TLR9-independent effects of inhibitory oligonucleotides on macrophage responses to S. typhimurium.

Immunol Cell Biol 2009 Mar-Apr;87(3):218-25. Epub 2008 Dec 2.

The University of Queensland, Institute for Molecular Bioscience, Queensland, Australia.

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http://dx.doi.org/10.1038/icb.2008.95DOI Listing
May 2009

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line.

Authors:
Harukazu Suzuki Alistair R R Forrest Erik van Nimwegen Carsten O Daub Piotr J Balwierz Katharine M Irvine Timo Lassmann Timothy Ravasi Yuki Hasegawa Michiel J L de Hoon Shintaro Katayama Kate Schroder Piero Carninci Yasuhiro Tomaru Mutsumi Kanamori-Katayama Atsutaka Kubosaki Altuna Akalin Yoshinari Ando Erik Arner Maki Asada Hiroshi Asahara Timothy Bailey Vladimir B Bajic Denis Bauer Anthony G Beckhouse Nicolas Bertin Johan Björkegren Frank Brombacher Erika Bulger Alistair M Chalk Joe Chiba Nicole Cloonan Adam Dawe Josee Dostie Pär G Engström Magbubah Essack Geoffrey J Faulkner J Lynn Fink David Fredman Ko Fujimori Masaaki Furuno Takashi Gojobori Julian Gough Sean M Grimmond Mika Gustafsson Megumi Hashimoto Takehiro Hashimoto Mariko Hatakeyama Susanne Heinzel Winston Hide Oliver Hofmann Michael Hörnquist Lukasz Huminiecki Kazuho Ikeo Naoko Imamoto Satoshi Inoue Yusuke Inoue Ryoko Ishihara Takao Iwayanagi Anders Jacobsen Mandeep Kaur Hideya Kawaji Markus C Kerr Ryuichiro Kimura Syuhei Kimura Yasumasa Kimura Hiroaki Kitano Hisashi Koga Toshio Kojima Shinji Kondo Takeshi Konno Anders Krogh Adele Kruger Ajit Kumar Boris Lenhard Andreas Lennartsson Morten Lindow Marina Lizio Cameron Macpherson Norihiro Maeda Christopher A Maher Monique Maqungo Jessica Mar Nicholas A Matigian Hideo Matsuda John S Mattick Stuart Meier Sei Miyamoto Etsuko Miyamoto-Sato Kazuhiko Nakabayashi Yutaka Nakachi Mika Nakano Sanne Nygaard Toshitsugu Okayama Yasushi Okazaki Haruka Okuda-Yabukami Valerio Orlando Jun Otomo Mikhail Pachkov Nikolai Petrovsky Charles Plessy John Quackenbush Aleksandar Radovanovic Michael Rehli Rintaro Saito Albin Sandelin Sebastian Schmeier Christian Schönbach Ariel S Schwartz Colin A Semple Miho Sera Jessica Severin Katsuhiko Shirahige Cas Simons George St Laurent Masanori Suzuki Takahiro Suzuki Matthew J Sweet Ryan J Taft Shizu Takeda Yoichi Takenaka Kai Tan Martin S Taylor Rohan D Teasdale Jesper Tegnér Sarah Teichmann Eivind Valen Claes Wahlestedt Kazunori Waki Andrew Waterhouse Christine A Wells Ole Winther Linda Wu Kazumi Yamaguchi Hiroshi Yanagawa Jun Yasuda Mihaela Zavolan David A Hume Takahiro Arakawa Shiro Fukuda Kengo Imamura Chikatoshi Kai Ai Kaiho Tsugumi Kawashima Chika Kawazu Yayoi Kitazume Miki Kojima Hisashi Miura Kayoko Murakami Mitsuyoshi Murata Noriko Ninomiya Hiromi Nishiyori Shohei Noma Chihiro Ogawa Takuma Sano Christophe Simon Michihira Tagami Yukari Takahashi Jun Kawai Yoshihide Hayashizaki

Nat Genet 2009 May 19;41(5):553-62. Epub 2009 Apr 19.

RIKEN Omics Science Center, RIKEN Yokohama Institute, Kanagawa, Japan.

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http://dx.doi.org/10.1038/ng.375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6711855PMC
May 2009