Matthew J Simmonds

Matthew J Simmonds

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Matthew J Simmonds

Matthew J Simmonds

Publications by authors named "Matthew J Simmonds"

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Caveolin-1 single-nucleotide polymorphism and arterial stiffness in non-dialysis chronic kidney disease.

Nephrol Dial Transplant 2016 07 3;31(7):1140-4. Epub 2015 Oct 3.

Department of Renal Medicine, Queen Elizabeth Hospital Birmingham, Birmingham, UK Centre for Translational Inflammation Research, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1093/ndt/gfv350DOI Listing
July 2016

Using Genetic Variation to Predict and Extend Long-term Kidney Transplant Function.

Transplantation 2015 Oct;99(10):2038-48

1 Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford, Churchill Hospital, Headington, Oxford, United Kingdom.

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http://dx.doi.org/10.1097/TP.0000000000000836DOI Listing
October 2015

Endothelial nitric oxide synthase single nucleotide polymorphism and left ventricular function in early chronic kidney disease.

PLoS One 2015 22;10(1):e0116160. Epub 2015 Jan 22.

Department of Nephrology, Queen Elizabeth Hospital Birmingham, Birmingham, B15 2WB, United Kingdom; Centre for Translational Inflammation Research, University of Birmingham, Birmingham, B15 2WB, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116160PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303420PMC
September 2015

Impact of month of birth on the development of autoimmune thyroid disease in the United Kingdom and Europe.

J Clin Endocrinol Metab 2014 Aug 19;99(8):E1459-65. Epub 2014 May 19.

Oxford Centre for Diabetes, Endocrinology, and Metabolism (A.H., J.A.H.W., S.C.L.G., M.J.S.), Department of Physiology, Anatomy, and Genetics (G.D., S.V.R.), and Oxford National Institute for Health Research Biomedical Research Centre (J.C.T.), Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7LE, United Kingdom; Centre for Endocrinology, Diabetes, and Metabolism (P.R.N., J.D.C.-S., J.A.F.), School of Clinical and Experimental Medicine, College of Medical and Dental Science, Institute of Biomedical Research, University of Birmingham, Birmingham B15 2TT, United Kingdom; Northern General Hospital (A.A.), Sheffield S5 7AU, United Kingdom; Royal Bournemouth Hospital (M.A.), Bournemouth BH7 7DW, United Kingdom; Department of Endocrinology and Metabolism (T.H.B., L.H.), Odense University Hospital, DK-5000 Odense, Denmark; Department of Medicine (K.C.), University of Cambridge, Cambridge CB2 1TN, United Kingdom; School of Medicine (J.M.C.), University of Dundee, Dundee DD1 9SY, United Kingdom; Department of Medicine (P.J.H.), University of Otago, Dunedein 9016, New Zealand; Centre for Endocrine and Diabetes Sciences (J.H.L.), Cardiff University, Cardiff C14 4XN, United Kingdom; Institute of Genetic Medicine (S.H.P.), Newcastle University, Newcastle-upon-Tyne NE1 3BZ, Newcastle, United Kingdom; Kolling Institute (B.G.R.), Royal North Shore Hospital and The University of Sydney, Sydney NSW 2006, Australia; Royal Devon and Exeter Hospital (B.V.), Exeter EX2 5DW, United Kingdom; Department of Endocrinology and Metabolism (W.M.W.), University of Amsterdam, 1100 DE Amsterdam, The Netherlands; Department of Human Metabolism (A.P.W.), University of Sheffield, Sheffield S10 2RX, United Kingdom; and Oxford National Institute for Health Research Biomedical Research Centre (S.C.L.G.), Churchill Hospital, Oxford OX3 7LE, United Kingdom.

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http://dx.doi.org/10.1210/jc.2014-1270DOI Listing
August 2014

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

Authors:
Marco Medici Eleonora Porcu Giorgio Pistis Alexander Teumer Suzanne J Brown Richard A Jensen Rajesh Rawal Greet L Roef Theo S Plantinga Sita H Vermeulen Jari Lahti Matthew J Simmonds Lise Lotte N Husemoen Rachel M Freathy Beverley M Shields Diana Pietzner Rebecca Nagy Linda Broer Layal Chaker Tim I M Korevaar Maria Grazia Plia Cinzia Sala Uwe Völker J Brent Richards Fred C Sweep Christian Gieger Tanguy Corre Eero Kajantie Betina Thuesen Youri E Taes W Edward Visser Andrew T Hattersley Jürgen Kratzsch Alexander Hamilton Wei Li Georg Homuth Monia Lobina Stefano Mariotti Nicole Soranzo Massimiliano Cocca Matthias Nauck Christin Spielhagen Alec Ross Alice Arnold Martijn van de Bunt Sandya Liyanarachchi Margit Heier Hans Jörgen Grabe Corrado Masciullo Tessel E Galesloot Ee M Lim Eva Reischl Peter J Leedman Sandra Lai Alessandro Delitala Alexandra P Bremner David I W Philips John P Beilby Antonella Mulas Matteo Vocale Goncalo Abecasis Tom Forsen Alan James Elisabeth Widen Jennie Hui Holger Prokisch Ernst E Rietzschel Aarno Palotie Peter Feddema Stephen J Fletcher Katharina Schramm Jerome I Rotter Alexander Kluttig Dörte Radke Michela Traglia Gabriela L Surdulescu Huiling He Jayne A Franklyn Daniel Tiller Bijay Vaidya Tim de Meyer Torben Jørgensen Johan G Eriksson Peter C O'Leary Eric Wichmann Ad R Hermus Bruce M Psaty Till Ittermann Albert Hofman Emanuele Bosi David Schlessinger Henri Wallaschofski Nicola Pirastu Yurii S Aulchenko Albert de la Chapelle Romana T Netea-Maier Stephen C L Gough Henriette Meyer Zu Schwabedissen Timothy M Frayling Jean-Marc Kaufman Allan Linneberg Katri Räikkönen Johannes W A Smit Lambertus A Kiemeney Fernando Rivadeneira André G Uitterlinden John P Walsh Christa Meisinger Martin den Heijer Theo J Visser Timothy D Spector Scott G Wilson Henry Völzke Anne Cappola Daniela Toniolo Serena Sanna Silvia Naitza Robin P Peeters

PLoS Genet 2014 Feb 27;10(2):e1004123. Epub 2014 Feb 27.

Department of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://repub.eur.nl/pub/65428/REPUB_65428_OA.pdf
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http://dx.plos.org/10.1371/journal.pgen.1004123
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http://dx.doi.org/10.1371/journal.pgen.1004123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937134PMC
February 2014

Skewed X chromosome inactivation and female preponderance in autoimmune thyroid disease: an association study and meta-analysis.

J Clin Endocrinol Metab 2014 Jan 20;99(1):E127-31. Epub 2013 Dec 20.

Oxford Centre for Diabetes, Endocrinology, and Metabolism (M.J.S., F.K.K., O.J.B., S.C.L.G.) and Oxford National Institute for Health Research Biomedical Research Centre (F.K.K., S.C.L.G.), Churchill Hospital, Headington, Oxford OX3 7LJ, United Kingdom; and Centre for Endocrinology, Diabetes, and Metabolism (P.R.N., L.E.J., C.E.H., J.A.F.), School of Clinical and Experimental Medicine, College of Medical and Dental Science, Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.

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http://dx.doi.org/10.1210/jc.2013-2667DOI Listing
January 2014

GWAS in autoimmune thyroid disease: redefining our understanding of pathogenesis.

Nat Rev Endocrinol 2013 May 26;9(5):277-87. Epub 2013 Mar 26.

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Headington, Oxford OX3 7LJ, UK.

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http://dx.doi.org/10.1038/nrendo.2013.56DOI Listing
May 2013

Seven newly identified loci for autoimmune thyroid disease.

Hum Mol Genet 2012 Dec 24;21(23):5202-8. Epub 2012 Aug 24.

Department of Medical Genetics, Cambridge Institute for Medical Research, Juvenile Diabetes Research Foundation/ Wellcome Trust Diabetes and Inflammation Laboratory, NIHR Cambridge Biomedical Research Centre, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK.

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http://dx.doi.org/10.1093/hmg/dds357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3490518PMC
December 2012

Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

PLoS Genet 2011 Aug 4;7(8):e1002216. Epub 2011 Aug 4.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150451PMC
August 2011

The search for the genetic contribution to autoimmune thyroid disease: the never ending story?

Brief Funct Genomics 2011 Mar;10(2):77-90

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Headington, UK.

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http://dx.doi.org/10.1093/bfgp/elq036DOI Listing
March 2011

Association of Fc receptor-like 5 (FCRL5) with Graves' disease is secondary to the effect of FCRL3.

Clin Endocrinol (Oxf) 2010 Nov;73(5):654-60

Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Headington, Oxford, UK.

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http://dx.doi.org/10.1111/j.1365-2265.2010.03843.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299549PMC
November 2010

Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study.

Eur J Hum Genet 2010 Sep 5;18(9):1021-6. Epub 2010 May 5.

Centre for Endocrinology, Diabetes and Metabolism, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, Institute of Biomedical Research, University of Birmingham, Birmingham, West Midlands, UK.

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http://dx.doi.org/10.1038/ejhg.2010.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987410PMC
September 2010

Association of FcGRIIa with Graves' disease: a potential role for dysregulated autoantibody clearance in disease onset/progression.

Clin Endocrinol (Oxf) 2010 Jul 10;73(1):119-25. Epub 2010 Feb 10.

Centre for Endocrinology, Diabetes and Metabolism, School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham, UK.

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http://dx.doi.org/10.1111/j.1365-2265.2010.03780.xDOI Listing
July 2010

Confirmation of association of chromosome 5q31-33 with United Kingdom Caucasian Graves' disease.

Thyroid 2010 Apr;20(4):413-7

Institute of Biomedical Research, University of Birmingham , Edgbaston, Birmingham, UK .

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http://dx.doi.org/10.1089/thy.2009.0375DOI Listing
April 2010

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls.

Authors:
Nick Craddock Matthew E Hurles Niall Cardin Richard D Pearson Vincent Plagnol Samuel Robson Damjan Vukcevic Chris Barnes Donald F Conrad Eleni Giannoulatou Chris Holmes Jonathan L Marchini Kathy Stirrups Martin D Tobin Louise V Wain Chris Yau Jan Aerts Tariq Ahmad T Daniel Andrews Hazel Arbury Anthony Attwood Adam Auton Stephen G Ball Anthony J Balmforth Jeffrey C Barrett Inês Barroso Anne Barton Amanda J Bennett Sanjeev Bhaskar Katarzyna Blaszczyk John Bowes Oliver J Brand Peter S Braund Francesca Bredin Gerome Breen Morris J Brown Ian N Bruce Jaswinder Bull Oliver S Burren John Burton Jake Byrnes Sian Caesar Chris M Clee Alison J Coffey John M C Connell Jason D Cooper Anna F Dominiczak Kate Downes Hazel E Drummond Darshna Dudakia Andrew Dunham Bernadette Ebbs Diana Eccles Sarah Edkins Cathryn Edwards Anna Elliot Paul Emery David M Evans Gareth Evans Steve Eyre Anne Farmer I Nicol Ferrier Lars Feuk Tomas Fitzgerald Edward Flynn Alistair Forbes Liz Forty Jayne A Franklyn Rachel M Freathy Polly Gibbs Paul Gilbert Omer Gokumen Katherine Gordon-Smith Emma Gray Elaine Green Chris J Groves Detelina Grozeva Rhian Gwilliam Anita Hall Naomi Hammond Matt Hardy Pile Harrison Neelam Hassanali Husam Hebaishi Sarah Hines Anne Hinks Graham A Hitman Lynne Hocking Eleanor Howard Philip Howard Joanna M M Howson Debbie Hughes Sarah Hunt John D Isaacs Mahim Jain Derek P Jewell Toby Johnson Jennifer D Jolley Ian R Jones Lisa A Jones George Kirov Cordelia F Langford Hana Lango-Allen G Mark Lathrop James Lee Kate L Lee Charlie Lees Kevin Lewis Cecilia M Lindgren Meeta Maisuria-Armer Julian Maller John Mansfield Paul Martin Dunecan C O Massey Wendy L McArdle Peter McGuffin Kirsten E McLay Alex Mentzer Michael L Mimmack Ann E Morgan Andrew P Morris Craig Mowat Simon Myers William Newman Elaine R Nimmo Michael C O'Donovan Abiodun Onipinla Ifejinelo Onyiah Nigel R Ovington Michael J Owen Kimmo Palin Kirstie Parnell David Pernet John R B Perry Anne Phillips Dalila Pinto Natalie J Prescott Inga Prokopenko Michael A Quail Suzanne Rafelt Nigel W Rayner Richard Redon David M Reid Renwick Susan M Ring Neil Robertson Ellie Russell David St Clair Jennifer G Sambrook Jeremy D Sanderson Helen Schuilenburg Carol E Scott Richard Scott Sheila Seal Sue Shaw-Hawkins Beverley M Shields Matthew J Simmonds Debbie J Smyth Elilan Somaskantharajah Katarina Spanova Sophia Steer Jonathan Stephens Helen E Stevens Millicent A Stone Zhan Su Deborah P M Symmons John R Thompson Wendy Thomson Mary E Travers Clare Turnbull Armand Valsesia Mark Walker Neil M Walker Chris Wallace Margaret Warren-Perry Nicholas A Watkins John Webster Michael N Weedon Anthony G Wilson Matthew Woodburn B Paul Wordsworth Allan H Young Eleftheria Zeggini Nigel P Carter Timothy M Frayling Charles Lee Gil McVean Patricia B Munroe Aarno Palotie Stephen J Sawcer Stephen W Scherer David P Strachan Chris Tyler-Smith Matthew A Brown Paul R Burton Mark J Caulfield Alastair Compston Martin Farrall Stephen C L Gough Alistair S Hall Andrew T Hattersley Adrian V S Hill Christopher G Mathew Marcus Pembrey Jack Satsangi Michael R Stratton Jane Worthington Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem Ouwehand Miles Parkes Nazneen Rahman John A Todd Nilesh J Samani Peter Donnelly

Nature 2010 Apr;464(7289):713-20

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http://dx.doi.org/10.1038/nature08979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892339PMC
April 2010

Association of caveolin-1 gene polymorphism with kidney transplant fibrosis and allograft failure.

JAMA 2010 Apr;303(13):1282-7

Department of Nephrology and Transplantation, Renal Institute of Birmingham, University Hospital Birmingham, Birmingham B15 2TH, England.

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http://dx.doi.org/10.1001/jama.2010.356DOI Listing
April 2010

Prevalence and relative risk of other autoimmune diseases in subjects with autoimmune thyroid disease.

Am J Med 2010 Feb;123(2):183.e1-9

School of Clinical and Experimental Medicine, College of Medical and Dental Sciences, Institute of Biomedical Research, University of Birmingham, Edgbaston, Birmingham, United Kingdom.

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http://dx.doi.org/10.1016/j.amjmed.2009.06.030DOI Listing
February 2010

Phenotypic differences in alpha 1 antitrypsin-deficient sibling pairs may relate to genetic variation.

COPD 2008 Dec;5(6):353-9

Department of Medical Sciences, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1080/15412550802522320DOI Listing
December 2008

The TNFalpha gene relates to clinical phenotype in alpha-1-antitrypsin deficiency.

Respir Res 2008 Jul 11;9:52. Epub 2008 Jul 11.

Division of Medical Sciences, The Medical School, University of Birmingham, Birmingham, B15 2TT, UK.

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http://dx.doi.org/10.1186/1465-9921-9-52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478658PMC
July 2008

Genetic developments in autoimmune thyroid disease: an evolutionary process.

Clin Endocrinol (Oxf) 2008 May 13;68(5):671-82. Epub 2007 Dec 13.

Division of Medical Sciences, Institute of Biomedical Research, University of Birmingham, Birmingham, B15 2TT, UK.

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http://dx.doi.org/10.1111/j.1365-2265.2007.03075.xDOI Listing
May 2008

Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants.

Authors:
Paul R Burton David G Clayton Lon R Cardon Nick Craddock Panos Deloukas Audrey Duncanson Dominic P Kwiatkowski Mark I McCarthy Willem H Ouwehand Nilesh J Samani John A Todd Peter Donnelly Jeffrey C Barrett Dan Davison Doug Easton David M Evans Hin-Tak Leung Jonathan L Marchini Andrew P Morris Chris C A Spencer Martin D Tobin Antony P Attwood James P Boorman Barbara Cant Ursula Everson Judith M Hussey Jennifer D Jolley Alexandra S Knight Kerstin Koch Elizabeth Meech Sarah Nutland Christopher V Prowse Helen E Stevens Niall C Taylor Graham R Walters Neil M Walker Nicholas A Watkins Thilo Winzer Richard W Jones Wendy L McArdle Susan M Ring David P Strachan Marcus Pembrey Gerome Breen David St Clair Sian Caesar Katharine Gordon-Smith Lisa Jones Christine Fraser Elaine K Green Detelina Grozeva Marian L Hamshere Peter A Holmans Ian R Jones George Kirov Valentina Moskivina Ivan Nikolov Michael C O'Donovan Michael J Owen David A Collier Amanda Elkin Anne Farmer Richard Williamson Peter McGuffin Allan H Young I Nicol Ferrier Stephen G Ball Anthony J Balmforth Jennifer H Barrett Timothy D Bishop Mark M Iles Azhar Maqbool Nadira Yuldasheva Alistair S Hall Peter S Braund Richard J Dixon Massimo Mangino Suzanne Stevens John R Thompson Francesca Bredin Mark Tremelling Miles Parkes Hazel Drummond Charles W Lees Elaine R Nimmo Jack Satsangi Sheila A Fisher Alastair Forbes Cathryn M Lewis Clive M Onnie Natalie J Prescott Jeremy Sanderson Christopher G Matthew Jamie Barbour M Khalid Mohiuddin Catherine E Todhunter John C Mansfield Tariq Ahmad Fraser R Cummings Derek P Jewell John Webster Morris J Brown Mark G Lathrop John Connell Anna Dominiczak Carolina A Braga Marcano Beverley Burke Richard Dobson Johannie Gungadoo Kate L Lee Patricia B Munroe Stephen J Newhouse Abiodun Onipinla Chris Wallace Mingzhan Xue Mark Caulfield Martin Farrall Anne Barton Ian N Bruce Hannah Donovan Steve Eyre Paul D Gilbert Samantha L Hilder Anne M Hinks Sally L John Catherine Potter Alan J Silman Deborah P M Symmons Wendy Thomson Jane Worthington David B Dunger Barry Widmer Timothy M Frayling Rachel M Freathy Hana Lango John R B Perry Beverley M Shields Michael N Weedon Andrew T Hattersley Graham A Hitman Mark Walker Kate S Elliott Christopher J Groves Cecilia M Lindgren Nigel W Rayner Nicolas J Timpson Eleftheria Zeggini Melanie Newport Giorgio Sirugo Emily Lyons Fredrik Vannberg Adrian V S Hill Linda A Bradbury Claire Farrar Jennifer J Pointon Paul Wordsworth Matthew A Brown Jayne A Franklyn Joanne M Heward Matthew J Simmonds Stephen C L Gough Sheila Seal Michael R Stratton Nazneen Rahman Maria Ban An Goris Stephen J Sawcer Alastair Compston David Conway Muminatou Jallow Melanie Newport Giorgio Sirugo Kirk A Rockett Suzannah J Bumpstead Amy Chaney Kate Downes Mohammed J R Ghori Rhian Gwilliam Sarah E Hunt Michael Inouye Andrew Keniry Emma King Ralph McGinnis Simon Potter Rathi Ravindrarajah Pamela Whittaker Claire Widden David Withers Niall J Cardin Dan Davison Teresa Ferreira Joanne Pereira-Gale Ingeleif B Hallgrimsdo'ttir Bryan N Howie Zhan Su Yik Ying Teo Damjan Vukcevic David Bentley Matthew A Brown Alastair Compston Martin Farrall Alistair S Hall Andrew T Hattersley Adrian V S Hill Miles Parkes Marcus Pembrey Michael R Stratton Sarah L Mitchell Paul R Newby Oliver J Brand Jackie Carr-Smith Simon H S Pearce R McGinnis A Keniry P Deloukas John D Reveille Xiaodong Zhou Anne-Marie Sims Alison Dowling Jacqueline Taylor Tracy Doan John C Davis Laurie Savage Michael M Ward Thomas L Learch Michael H Weisman Mathew Brown

Nat Genet 2007 Nov 21;39(11):1329-37. Epub 2007 Oct 21.

Genetic Epidemiology Group, Department of Health Sciences, University of Leicester, Adrian Building, University Road, Leicester LE1 7RH, UK.

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http://dx.doi.org/10.1038/ng.2007.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680141PMC
November 2007

A novel and major association of HLA-C in Graves' disease that eclipses the classical HLA-DRB1 effect.

Hum Mol Genet 2007 Sep 27;16(18):2149-53. Epub 2007 Jun 27.

Division of Medical Sciences, University of Birmingham, UK.

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http://dx.doi.org/10.1093/hmg/ddm165DOI Listing
September 2007

Regression mapping of association between the human leukocyte antigen region and Graves disease.

Am J Hum Genet 2005 Jan 22;76(1):157-63. Epub 2004 Nov 22.

Division of Medical Sciences, Institute of Biomedical Research, University of Birmingham, and Birmingham Heartlands Hospital, Birmingham B9 5SS, United Kingdom.

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http://dx.doi.org/10.1086/426947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1196419PMC
January 2005

A single nucleotide polymorphism in the CD40 gene on chromosome 20q (GD-2) provides no evidence for susceptibility to Graves' disease in UK Caucasians.

Clin Endocrinol (Oxf) 2004 Aug;61(2):269-72

Division of Medical Sciences, University of Birmingham, Institute of Biomedical Research, Edgbaston, Birmingham, UK, B15 2TT.

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http://dx.doi.org/10.1111/j.1365-2265.2004.02099.xDOI Listing
August 2004