Matthew J Schiewer

Matthew J Schiewer

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Matthew J Schiewer

Matthew J Schiewer

Publications by authors named "Matthew J Schiewer"

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DNA Damage Response in Prostate Cancer.

Cold Spring Harb Perspect Med 2019 Jan 2;9(1). Epub 2019 Jan 2.

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania,19107.

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http://dx.doi.org/10.1101/cshperspect.a030486DOI Listing
January 2019

Detection of Activating Estrogen Receptor Gene () Mutations in Single Circulating Tumor Cells.

Clin Cancer Res 2017 Oct 5;23(20):6086-6093. Epub 2017 Jul 5.

Department of Cancer Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-1173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641250PMC
October 2017

PARP Inhibitors in Prostate Cancer.

Curr Treat Options Oncol 2017 06;18(6):37

Departments of Medical Oncology, The Sidney Kimmel Cancer Center at Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/s11864-017-0480-2DOI Listing
June 2017

Not So Fast: Cultivating miRs as Kinks in the Chain of the Cell Cycle.

Cancer Cell 2017 04;31(4):471-473

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Department of Medical Oncology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Department of Urology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA 19107, USA; The Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5709809PMC
April 2017

Linking DNA Damage and Hormone Signaling Pathways in Cancer.

Trends Endocrinol Metab 2016 Apr 1;27(4):216-225. Epub 2016 Mar 1.

Sidney Kimmel Cancer Center, Thomas Jefferson University, 233 S 10th St Philadelphia, PA 19107, USA; Department of Cancer Biology, Thomas Jefferson University, 233 S 10th St Philadelphia, PA 19107, USA; Department of Urology, Thomas Jefferson University, 233 S 10th St Philadelphia, PA 19107, USA; Department of Radiation Oncology, Thomas Jefferson University, 233 S 10th St Philadelphia, PA 19107, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tem.2016.02.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808434PMC
April 2016

DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis.

Cancer Cell 2015 Jul;28(1):97-113

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Department of Urology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA 19107, USA; Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4531387PMC
July 2015

Consequence of the tumor-associated conversion to cyclin D1b.

EMBO Mol Med 2015 May;7(5):628-47

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA Department of Urology, Thomas Jefferson University, Philadelphia, PA, USA Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, PA, USA

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http://dx.doi.org/10.15252/emmm.201404242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492821PMC
May 2015

Novel actions of next-generation taxanes benefit advanced stages of prostate cancer.

Clin Cancer Res 2015 Feb;21(4):795-807

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, Pennsylvania. Department of Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania. Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania. Department of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania. Department of Urology, Thomas Jefferson University, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-14-1358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333741PMC
February 2015

Transcriptional roles of PARP1 in cancer.

Mol Cancer Res 2014 Aug 10;12(8):1069-80. Epub 2014 Jun 10.

Kimmel Cancer Center, Departments of Cancer Biology, Urology, and Radiation Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania

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http://dx.doi.org/10.1158/1541-7786.MCR-13-0672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134958PMC
August 2014

AMPed up to treat prostate cancer: novel AMPK activators emerge for cancer therapy.

EMBO Mol Med 2014 04 20;6(4):439-41. Epub 2014 Feb 20.

Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1002/emmm.201303737DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992071PMC
April 2014

Progesterone receptor-cyclin D1 complexes induce cell cycle-dependent transcriptional programs in breast cancer cells.

Mol Endocrinol 2014 Apr 25;28(4):442-57. Epub 2014 Feb 25.

Departments of Medicine and Pharmacology (G.E.D., T.P.K., A.R.D., C.R.H., C.H.D., C.A.L.), Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455; and Departments of Cancer Biology, Urology, and Radiation Oncology (M.J.S., K.E.K.), Kimmel Cancer Center Thomas Jefferson University, Philadelphia, Pennsylvania 19107.

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http://dx.doi.org/10.1210/me.2013-1196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968407PMC
April 2014

Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer.

Cancer Res 2014 Jan 4;74(1):31-7. Epub 2013 Nov 4.

Authors' Affiliations: Departments of Biochemistry and Molecular Biology and Surgery, Division of Surgical Research, The Jefferson Pancreas, Biliary, and Related Cancer Center; and Department of Cancer Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-1701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903668PMC
January 2014

USP22 regulates oncogenic signaling pathways to drive lethal cancer progression.

Cancer Res 2014 Jan 6;74(1):272-86. Epub 2013 Nov 6.

Authors' Affiliations: Departments of Cancer Biology, Urology, Radiation Oncology, Pathology, and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania; Sidney Kimmel Comprehensive Cancer Center; Department of Pathology, Johns Hopkins University, Baltimore, Maryland; and Institute of Biomedical Technology, University of Tampere and Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947329PMC
January 2014

A hormone-DNA repair circuit governs the response to genotoxic insult.

Cancer Discov 2013 Nov 11;3(11):1254-71. Epub 2013 Sep 11.

Departments of 1Cancer Biology, 2Urology, and 3Radiation Oncology, and 4Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania; 5Michigan Center for Translational Pathology, 6Department of Radiation Oncology, and 7Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823813PMC
November 2013

The AR dependent cell cycle: mechanisms and cancer relevance.

Mol Cell Endocrinol 2012 Apr 12;352(1-2):34-45. Epub 2011 Jul 12.

Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.1016/j.mce.2011.06.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3641823PMC
April 2012

mTOR is a selective effector of the radiation therapy response in androgen receptor-positive prostate cancer.

Endocr Relat Cancer 2012 Feb 9;19(1):1-12. Epub 2012 Jan 9.

Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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http://dx.doi.org/10.1530/ERC-11-0072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3253653PMC
February 2012