Matthew J Merrins

Matthew J Merrins

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Matthew J Merrins

Matthew J Merrins

Publications by authors named "Matthew J Merrins"

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24Publications

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Age-Dependent Protection of Insulin Secretion in Diet Induced Obese Mice.

Sci Rep 2018 12 13;8(1):17814. Epub 2018 Dec 13.

Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, and the William S. Middleton Memorial Veterans Hospital, Madison, WI, USA.

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http://dx.doi.org/10.1038/s41598-018-36289-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292902PMC
December 2018

Pancreatic β-Cells From Mice Offset Age-Associated Mitochondrial Deficiency With Reduced KATP Channel Activity.

Diabetes 2016 09 9;65(9):2700-10. Epub 2016 Jun 9.

Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Wisconsin-Madison, Madison, WI Laboratory for Optical and Computational Instrumentation, University of Wisconsin-Madison, Madison, WI Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI William S. Middleton Memorial Veterans Hospital, Madison, WI

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http://dx.doi.org/10.2337/db16-0432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001174PMC
September 2016

Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health.

Cell Rep 2016 07 23;16(2):520-530. Epub 2016 Jun 23.

Department of Medicine, University of Wisconsin-Madison, Madison, WI 53705, USA; William S. Middleton Memorial Veterans Hospital, Madison, WI 53705, USA; Endocrinology and Reproductive Physiology Graduate Training Program, University of Wisconsin-Madison, Madison, WI 53706, USA; Interdisciplinary Graduate Program in Nutritional Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA; Rural and Urban Scholars in Community Health Program, University of Wisconsin-Madison, Madison, WI 53706, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.05.092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4947548PMC
July 2016

Phase Analysis of Metabolic Oscillations and Membrane Potential in Pancreatic Islet β-Cells.

Biophys J 2016 Feb;110(3):691-699

Department of Pharmacology and Brehm Diabetes Center, University of Michigan, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2015.12.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744170PMC
February 2016

Ca2+ Effects on ATP Production and Consumption Have Regulatory Roles on Oscillatory Islet Activity.

Biophys J 2016 Feb;110(3):733-742

Department of Mathematics, Florida State University, Tallahassee, Florida; Programs in Neuroscience and Molecular Biophysics, Florida State University, Tallahassee, Florida. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2015.11.3526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744176PMC
February 2016

Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell.

J Biol Chem 2014 Nov 30;289(47):32798-810. Epub 2014 Sep 30.

From the Departments of Biochemistry and Molecular Biology, Medicine, and Cellular and Integrative Physiology and the Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202, the Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana 46202

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http://dx.doi.org/10.1074/jbc.M114.575191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4239629PMC
November 2014

Calcium and Metabolic Oscillations in Pancreatic Islets: Who's Driving the Bus?

SIAM J Appl Dyn Syst 2014;13(2):683-703

National Institutes of Health, Bethesda, MD 20892. The first and sixth authors' research was supported by the NIH/NIDDK Intramural Research Program.

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http://dx.doi.org/10.1137/130920198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331037PMC
January 2014

Direct measurements of oscillatory glycolysis in pancreatic islet β-cells using novel fluorescence resonance energy transfer (FRET) biosensors for pyruvate kinase M2 activity.

J Biol Chem 2013 Nov 7;288(46):33312-22. Epub 2013 Oct 7.

From the Department of Pharmacology and Brehm Center for Diabetes Research, University of Michigan Medical School, Ann Arbor, Michigan 48105.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M113.508127
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http://dx.doi.org/10.1074/jbc.M113.508127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3829177PMC
November 2013

Phosphofructo-2-kinase/fructose-2,6-bisphosphatase modulates oscillations of pancreatic islet metabolism.

PLoS One 2012 20;7(4):e34036. Epub 2012 Apr 20.

Department of Pharmacology and Brehm Diabetes Center, University of Michigan, Ann Arbor, Michigan, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0034036PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3332096PMC
August 2012

Metabolic oscillations in pancreatic islets depend on the intracellular Ca2+ level but not Ca2+ oscillations.

Biophys J 2010 Jul;99(1):76-84

Department of Pharmacology and Brehm Diabetes Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1016/j.bpj.2010.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895383PMC
July 2010

Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic beta-cells.

J Physiol 2008 Nov 18;586(22):5367-81. Epub 2008 Sep 18.

Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109-0622, USA.

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http://dx.doi.org/10.1113/jphysiol.2008.158477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655366PMC
November 2008