Matthew J Kolar

Matthew J Kolar

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Matthew J Kolar

Matthew J Kolar

Publications by authors named "Matthew J Kolar"

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16Publications

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Stereochemistry of Linoleic Acid Esters of Hydroxy Linoleic Acids.

Org Lett 2019 10 23;21(19):8080-8084. Epub 2019 Sep 23.

Skaggs School of Pharmacy and Pharmaceutical Sciences , UC San Diego , 9500 Gilman Drive , La Jolla , California 92093-0934 , United States.

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http://dx.doi.org/10.1021/acs.orglett.9b03054DOI Listing
October 2019

Linoleic acid esters of hydroxy linoleic acids are anti-inflammatory lipids found in plants and mammals.

J Biol Chem 2019 07 31;294(27):10698-10707. Epub 2019 May 31.

From the Clayton Foundation Laboratories for Peptide Biology, Salk Institute for Biological Studies, La Jolla, California 92037,

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http://dx.doi.org/10.1074/jbc.RA118.006956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615670PMC
July 2019

Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements.

Anal Chem 2018 04 26;90(8):5358-5365. Epub 2018 Mar 26.

Clayton Foundation Laboratories for Peptide Biology , Salk Institute for Biological Studies , 10010 North Torrey Pines Road , La Jolla , California 92037 , United States.

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http://dx.doi.org/10.1021/acs.analchem.8b00503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962352PMC
April 2018

Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.

Cell Metab 2018 02;27(2):419-427.e4

Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Center for Life Sciences, Room 747, 330 Brookline Avenue, Boston, MA 02215, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2018.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807007PMC
February 2018

Pharmacological activation of REV-ERBs is lethal in cancer and oncogene-induced senescence.

Nature 2018 01 10;553(7688):351-355. Epub 2018 Jan 10.

Regulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California 92037, USA.

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http://www.nature.com/doifinder/10.1038/nature25170
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http://dx.doi.org/10.1038/nature25170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924733PMC
January 2018

Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation.

J Am Chem Soc 2017 04 28;139(13):4943-4947. Epub 2017 Mar 28.

Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California-San Diego , 9500 Gilman Drive, La Jolla, California 92093-0934, United States.

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http://pubs.acs.org/doi/10.1021/jacs.7b01269
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http://dx.doi.org/10.1021/jacs.7b01269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568760PMC
April 2017

Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex.

Cell Metab 2017 02 12;25(2):463-471. Epub 2017 Jan 12.

Department of Genetics and Complex Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5299044PMC
February 2017

Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis.

Proc Natl Acad Sci U S A 2017 01 3;114(3):580-585. Epub 2017 Jan 3.

Department of Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390;

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http://dx.doi.org/10.1073/pnas.1614035114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5255630PMC
January 2017

Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase.

Biochemistry 2016 08 10;55(33):4636-41. Epub 2016 Aug 10.

Peptide Biology Laboratories, Helmsley Center for Genomic Medicine, Salk Institute for Biological Studies , La Jolla, California 92037, United States.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056623PMC
http://dx.doi.org/10.1021/acs.biochem.6b00565DOI Listing
August 2016

AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs.

Nat Chem Biol 2016 May 28;12(5):367-372. Epub 2016 Mar 28.

The Skaggs Institute for Chemical Biology, Department of Chemical Physiology, The Scripps Research Institute, La Jolla, CA 92037.

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http://dx.doi.org/10.1038/nchembio.2051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4837090PMC
May 2016