Matthew J Farrer

Matthew J Farrer

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Matthew J Farrer

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Pathophysiology of and therapeutic options for a GABRA1 variant linked to epileptic encephalopathy.

Mol Brain 2019 Nov 10;12(1):92. Epub 2019 Nov 10.

Djavad Mowafaghian Centre for Brain Health and Department of Medicine, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1186/s13041-019-0513-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842544PMC
November 2019

Family with primary periodic paralysis and a mutation in MCM3AP, a gene implicated in mRNA transport.

Muscle Nerve 2019 Sep 7;60(3):311-314. Epub 2019 Jul 7.

Department of Neurology, St. Olav's Hospital, Trondheim, Norway.

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http://dx.doi.org/10.1002/mus.26622DOI Listing
September 2019

Whole-Exome Sequencing of an Exceptional Longevity Cohort.

J Gerontol A Biol Sci Med Sci 2019 Aug;74(9):1386-1390

Program in Cellular Neuroscience, Neurodegeneration and Repair (CNNR), Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1093/gerona/gly098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696723PMC
August 2019

Mitochondrial DNA Deletions Discriminate Affected from Unaffected LRRK2 Mutation Carriers.

Ann Neurol 2019 Aug 12;86(2):324-326. Epub 2019 Jun 12.

Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg.

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http://dx.doi.org/10.1002/ana.25510DOI Listing
August 2019

DNAJC13 p.Asn855Ser, implicated in familial parkinsonism, alters membrane dynamics of sorting nexin 1.

Neurosci Lett 2019 07 11;706:114-122. Epub 2019 May 11.

Centre for Applied Neurogenetics, Department of Medical Genetics, University of British Columbia, Vancouver, B.C., Canada.

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http://dx.doi.org/10.1016/j.neulet.2019.04.043DOI Listing
July 2019

Endosomal trafficking leads the way in Parkinson's disease.

Mov Disord 2019 04 27;34(4):443-445. Epub 2019 Feb 27.

Centre for Applied Neurogenetics, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/mds.27647DOI Listing
April 2019

Single Inflammatory Trigger Leads to Neuroinflammation in LRRK2 Rodent Model without Degeneration of Dopaminergic Neurons.

J Parkinsons Dis 2019 ;9(1):121-139

Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.3233/JPD-181446DOI Listing
January 2019

A Meta-Analysis of α-Synuclein Multiplication in Familial Parkinsonism.

Front Neurol 2018 11;9:1021. Epub 2018 Dec 11.

Department of Medical Genetics, Centre for Applied Neurogenetics, University of British Columbia, Vancouver, BC, Canada.

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https://www.frontiersin.org/article/10.3389/fneur.2018.01021
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http://dx.doi.org/10.3389/fneur.2018.01021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297377PMC
December 2018

Assessing an Interactive Online Tool to Support Parents' Genomic Testing Decisions.

J Genet Couns 2018 Jul 23. Epub 2018 Jul 23.

Department of Medical Genetics, University of British Columbia, Box 153, 4500 Oak Street, Vancouver, BC, V6H 3N1, Canada.

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http://dx.doi.org/10.1007/s10897-018-0281-1DOI Listing
July 2018

A Case of Parkinson's Disease with No Lewy Body Pathology due to a Homozygous Exon Deletion in .

Case Rep Neurol Med 2018 28;2018:6838965. Epub 2018 Jun 28.

Department of Neurology, St. Olavs University Hospital, Trondheim, Norway.

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http://dx.doi.org/10.1155/2018/6838965DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046180PMC
June 2018

Pipeline to gene discovery - Analysing familial Parkinsonism in the Queensland Parkinson's Project.

Parkinsonism Relat Disord 2018 04 3;49:34-41. Epub 2018 Jan 3.

Griffith Institute for Drug Discovery, Griffith University, Don Young Road, Nathan, Queensland, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2017.12.033DOI Listing
April 2018

The emerging role of Rab GTPases in the pathogenesis of Parkinson's disease.

Mov Disord 2018 02 9;33(2):196-207. Epub 2018 Jan 9.

Bruce Lefroy Centre for Genetic Health Research, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/mds.27270DOI Listing
February 2018

p.Met233Val in a Complex Neurodegenerative Movement and Neuropsychiatric Disorder.

J Mov Disord 2018 Jan 11;11(1):45-48. Epub 2018 Jan 11.

Pacific Parkinson's Research Centre and Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.14802/jmd.17066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5790629PMC
January 2018

An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2.

Pediatr Neurol 2017 Oct 8;75:87-90. Epub 2017 Jun 8.

Division of Neurology, Department of Pediatrics, University of British Columbia and BC Children's Hospital, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pediatrneurol.2017.06.003DOI Listing
October 2017

Neurobehavioral characterization of adult-onset Alexander disease: A family study.

Neurol Clin Pract 2017 Oct;7(5):425-429

Division of Neurology, Department of Medicine (MLL, HBN, SH, JJSB, HHF), Department of Medical Genetics, Faculty of Medicine (ED), Centre for Applied Neurogenetics, Department of Medical Genetics (MJF, MBM, IG, DME), Division of Neuroradiology, Department of Radiology (JRS), and Department of Ophthalmology and Visual Sciences (JJSB), University of British Columbia, Vancouver, Canada; Department of Geriatric Medicine (ARC), Khoo Teck Puat Hospital, Singapore; and Department of Neuroscience (HHF), University of California San Diego.

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http://dx.doi.org/10.1212/CPJ.0000000000000356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874457PMC
October 2017

Homozygous alpha-synuclein p.A53V in familial Parkinson's disease.

Neurobiol Aging 2017 09 27;57:248.e7-248.e12. Epub 2017 Jun 27.

Research Institute for Diseases of Old Age, Graduate School of Medicine, Juntendo University, Tokyo, Japan; Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.05.022DOI Listing
September 2017

SCA2 family presenting as typical Parkinson's disease: 34 year follow up.

Parkinsonism Relat Disord 2017 Jul 12;40:69-72. Epub 2017 Apr 12.

Graduate School of Convergence Science and Technology, Seoul National University, Suwon, Republic of Korea.

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http://dx.doi.org/10.1016/j.parkreldis.2017.04.003DOI Listing
July 2017

Genetic Identification in Early Onset Parkinsonism among Norwegian Patients.

Mov Disord Clin Pract 2017 Jul-Aug;4(4):499-508. Epub 2017 May 23.

Department of Neuroscience Norwegian University of Science and Technology Trondheim Norway.

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http://doi.wiley.com/10.1002/mdc3.12501
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http://dx.doi.org/10.1002/mdc3.12501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174458PMC
May 2017

Gender differences in Parkinson's disease depression.

Parkinsonism Relat Disord 2017 03 29;36:93-97. Epub 2016 Dec 29.

Pacific Parkinson's Research Centre, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 2B5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2016.12.026DOI Listing
March 2017

Conjugal parkinsonism is coincidental.

Parkinsonism Relat Disord 2016 12 7;33:149-150. Epub 2016 Oct 7.

Saskatchewan Movement Disorders Program, University of Saskatchewan/Saskatoon Health Region, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S13538020163039
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http://dx.doi.org/10.1016/j.parkreldis.2016.10.004DOI Listing
December 2016

De novo mutation in 2 patients with neonatal-onset epilepsy.

Neurol Genet 2016 Dec 10;2(6):e120. Epub 2016 Nov 10.

Centre for Applied Neurogenetics (CAN), Department of Medical Genetics (I.G., M.B.M., D.M.E., M.J.F.), Division of Neurology (L.H., E.B.T., S.E.B., M.B.C., M.D.), Department of Pediatrics, University of British Columbia and BC Children's Hospital, Vancouver, Canada; Department of Neurology (E.M.B.), University of Alabama at Birmingham; HudsonAlpha Institute for Biotechnology (M.L.T., G.M.C.), Huntsville, AL; Department of Medical Genetics (S.A., M.I.V.A.), University of British Columbia, Vancouver, Canada; and Departments of Pathology and Laboratory Medicine (T.N.N.), University of British Columbia and BC Children's Hospital, Vancouver, Canada.

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http://dx.doi.org/10.1212/NXG.0000000000000120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113095PMC
December 2016

Leucine-rich repeat kinase 2 (LRRK2) regulates α-synuclein clearance in microglia.

BMC Neurosci 2016 11 30;17(1):77. Epub 2016 Nov 30.

Division of Clinical Immunology, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa, 252-0373, Japan.

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http://dx.doi.org/10.1186/s12868-016-0315-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131420PMC
November 2016

Conjugal parkinsonism - Clinical, pathology and genetic study. No evidence of person-to-person transmission.

Parkinsonism Relat Disord 2016 10 26;31:87-90. Epub 2016 Jul 26.

Saskatchewan Movement Disorders Program, University of Saskatchewan/Saskatoon Health Region, Canada.

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http://dx.doi.org/10.1016/j.parkreldis.2016.07.011DOI Listing
October 2016

DCTN1 p.K56R in progressive supranuclear palsy.

Parkinsonism Relat Disord 2016 07 23;28:56-61. Epub 2016 Apr 23.

Centre for Applied Neurogenetics, Djavad Mowafaghian Centre for Brain Health, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2016.04.025DOI Listing
July 2016

α-synuclein genetic variability: A biomarker for dementia in Parkinson disease.

Ann Neurol 2016 Jun 5;79(6):991-9. Epub 2016 May 5.

Centre for Applied Neurogenetics, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.

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http://doi.wiley.com/10.1002/ana.24664
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http://dx.doi.org/10.1002/ana.24664DOI Listing
June 2016

Lovastatin protects neurite degeneration in LRRK2-G2019S parkinsonism through activating the Akt/Nrf pathway and inhibiting GSK3β activity.

Hum Mol Genet 2016 05 29;25(10):1965-1978. Epub 2016 Feb 29.

Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan.

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http://dx.doi.org/10.1093/hmg/ddw068DOI Listing
May 2016

Double homozygous mutations (R275W and M432V) in the ParkinGene associated with late-onset Parkinson's disease.

Mov Disord 2016 Mar 10;31(3):423-5. Epub 2016 Feb 10.

Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

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http://dx.doi.org/10.1002/mds.26524DOI Listing
March 2016

Leucine-rich repeat kinase 2 is a regulator of B cell function, affecting homeostasis, BCR signaling, IgA production, and TI antigen responses.

J Neuroimmunol 2016 Mar 8;292:1-8. Epub 2016 Jan 8.

Division of Immunology, Kitasato University School of Allied Health Sciences, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan; Division of Clinical Immunology, Graduate School of Medical Sciences, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan; Research Facility of Regenerative Medicine and Cell Design, Kitasato University School of Allied Health Sciences, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan.

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http://dx.doi.org/10.1016/j.jneuroim.2016.01.005DOI Listing
March 2016

Insights from late-onset familial parkinsonism on the pathogenesis of idiopathic Parkinson's disease.

Lancet Neurol 2015 Oct;14(10):1054-64

Department of Medical Genetics, Centre for Applied Neurogenetics, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(15)00186-6DOI Listing
October 2015

Novel LRRK2 mutations in Parkinsonism.

Parkinsonism Relat Disord 2015 Sep 18;21(9):1119-21. Epub 2015 Jul 18.

Djavad Mowafaghian Centre for Brain Health, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada; Pacific Parkinson's Research Centre, Department of Medicine (Neurology), University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.parkreldis.2015.07.011DOI Listing
September 2015

[11C]PBR28 PET imaging is sensitive to neuroinflammation in the aged rat.

J Cereb Blood Flow Metab 2015 Aug 1;35(8):1331-8. Epub 2015 Apr 1.

Department of Physics and Astronomy, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1038/jcbfm.2015.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528008PMC
August 2015

Parkinsonism in GTP cyclohydrolase 1 mutation carriers.

Brain 2015 May 13;138(Pt 5):e349. Epub 2014 Dec 13.

1 Djavad Mowafaghian Centre for Brain Health, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1093/brain/awu341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963401PMC
May 2015

Genetic variability of the retromer cargo recognition complex in parkinsonism.

Mov Disord 2015 Apr 5;30(4):580-4. Epub 2014 Dec 5.

Djavad Mowafaghian Centre for Brain Health, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada; Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway; Department of Neurology, St. Olav's Hospital, Trondheim, Norway.

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http://doi.wiley.com/10.1002/mds.26104
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http://dx.doi.org/10.1002/mds.26104DOI Listing
April 2015

Familial aggregation of Parkinson's disease in the Faroe Islands.

Mov Disord 2015 Apr 20;30(4):538-44. Epub 2015 Jan 20.

Department of Occupational Medicine and Public Health, the Faroese Hospital System, Tórshavn, Faroe Islands.

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http://dx.doi.org/10.1002/mds.26132DOI Listing
April 2015

DNAJC13 genetic variants in parkinsonism.

Mov Disord 2015 Feb 12;30(2):273-8. Epub 2014 Nov 12.

Djavad Mowafaghian Centre for Brain Health, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada; Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway; Department of Neurology, St. Olav's Hospital, Trondheim, Norway.

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http://dx.doi.org/10.1002/mds.26064DOI Listing
February 2015

Motor phenotype of LRRK2-associated Parkinson's disease: a Tunisian longitudinal study.

Mov Disord 2015 Feb 9;30(2):253-8. Epub 2014 Dec 9.

Neurology Department, National Institute Mongi Ben Hmida of Neurology, Faculty of Medicine of Tunis, University Tunis El Manar, Tunis, Tunisia.

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http://dx.doi.org/10.1002/mds.26097DOI Listing
February 2015

Parkinson's disease, genetic variability and the Faroe Islands.

Parkinsonism Relat Disord 2015 Jan 4;21(1):75-8. Epub 2014 Nov 4.

Djavad Mowafaghian Centre for Brain Health, Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2014.10.027DOI Listing
January 2015

LRRK2 exonic variants and risk of multiple system atrophy.

Neurology 2014 Dec 5;83(24):2256-61. Epub 2014 Nov 5.

From the Section of Biostatistics (M.G.H., N.N.D.) and Departments of Neuroscience (A.I.S.-O., S.R., K.O., M.E.M., D.W.D., O.A.R.) and Neurology (S.F., W.P.C., R.J.U., Z.K.W.), Mayo Clinic, Jacksonville, FL; Department of Molecular Neuroscience (L.S., A.S., H.H.), Institute of Neurology and The National Hospital for Neurology and Neurosurgery, Queen Square, London, UK; Department of Medical Genetics (M.J.F.), University of British Columbia, Vancouver, Canada; Laboratory of Neurogenetics (A.B.S.), National Institute on Aging, Bethesda, MD; Institute of Genetic Medicine (P.F.C., M.J.K.), Newcastle University, Central Parkway, Newcastle upon Tyne; Neuropathology Unit (S.M.G.), Department of Medicine, Imperial College London; Queen Square Brain Bank for Neurological Disorders (J.L.H., K.A.), Department of Molecular Neuroscience, UCL Institute of Neurology, University College London; Clinical and Cognitive Sciences Research Group (D.M.A.M.), Institute of Brain, Behavior and Mental Health, Faculty of Medical and Human Sciences, University of Manchester, Salford Royal Hospital, Salford; and MRC London Neurodegenerative Diseases Brain Bank (S.A.-S., C.T.), King's College London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000001078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4277668PMC
December 2014

Clinical, positron emission tomography, and pathological studies of DNAJC13 p.N855S Parkinsonism.

Mov Disord 2014 Nov 3;29(13):1684-7. Epub 2014 Sep 3.

Pacific Parkinson's Research Center, Division of Neurology, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/mds.26019DOI Listing
November 2014

Synaptic function is modulated by LRRK2 and glutamate release is increased in cortical neurons of G2019S LRRK2 knock-in mice.

Front Cell Neurosci 2014 26;8:301. Epub 2014 Sep 26.

Centre for Applied Neurogenetics, Medical Genetics, University of British Columbia Vancouver, BC, Canada ; Djavad Mowafaghian Centre for Brain Health, Faculty of Medicine, University of British Columbia Vancouver, BC, Canada ; Division of Neurology, University of British Columbia Vancouver, BC, Canada.

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http://dx.doi.org/10.3389/fncel.2014.00301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176085PMC
October 2014

A novel DCTN1 mutation with late-onset parkinsonism and frontotemporal atrophy.

Mov Disord 2014 Aug 22;29(9):1201-4. Epub 2014 Feb 22.

Department of Neurology, National Omuta Hospital, Fukuoka, Japan.

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http://dx.doi.org/10.1002/mds.25833DOI Listing
August 2014

LRRK2 parkinsonism in Tunisia and Norway: a comparative analysis of disease penetrance.

Neurology 2014 Aug 9;83(6):568-9. Epub 2014 Jul 9.

From Institut National Mongi Ben Hamida de Neurologie (F.H.), La Rabta, Tunis, Tunisia; the University of British Columbia (J.T., C.T., E.N., M.J.F.), Vancouver; and St. Olav's Hospital (J.O.A.), Norwegian University of Science and Technology, Trondheim, Norway.

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http://dx.doi.org/10.1212/WNL.0000000000000675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142000PMC
August 2014

Genetics and genomics of Parkinson's disease.

Genome Med 2014 30;6(6):48. Epub 2014 Jun 30.

Djavad Mowafaghian Centre for Brain Health, Centre for Applied Neurogenetics, Department of Medical Genetics, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.

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http://dx.doi.org/10.1186/gm566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4085542PMC
July 2014

Patient-control association study of the Leucine-Rich repeat kinase 2 (LRRK2) gene in South African Parkinson's disease patients.

Mov Disord 2013 Dec 6;28(14):2039-40. Epub 2013 Sep 6.

Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, University of Stellenbosch, Cape Town, South Africa.

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http://dx.doi.org/10.1002/mds.25637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859714PMC
December 2013

LRRK2 phosphorylates novel tau epitopes and promotes tauopathy.

Acta Neuropathol 2013 Dec 11;126(6):809-27. Epub 2013 Oct 11.

Department of Neuroscience, Center for Translational Research in Neurodegenerative Disease, University of Florida, Gainesville, FL, 32610, USA.

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http://dx.doi.org/10.1007/s00401-013-1188-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830748PMC
December 2013

Measuring dopaminergic function in the 6-OHDA-lesioned rat: a comparison of PET and microdialysis.

EJNMMI Res 2013 Oct 2;3(1):69. Epub 2013 Oct 2.

Department of Physics and Astronomy, University of British Columbia, 6224 Agricultural Road, Vancouver, British Columbia V6T 1Z1, Canada.

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http://dx.doi.org/10.1186/2191-219X-3-69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875899PMC
October 2013

Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease.

Mov Disord 2013 Jun 1;28(6):811-3. Epub 2013 Mar 1.

Department of Medicine (Neurology), Pacific Parkinson's Research Centre, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/mds.25421DOI Listing
June 2013

STX6 rs1411478 is not associated with increased risk of Parkinson's disease.

Parkinsonism Relat Disord 2013 May 14;19(5):563-5. Epub 2013 Feb 14.

Department of Medical Genetics, Centre for Applied Neurogenetics, University of British Columbia, Vancouver, BC, Canada V6T 2B5.

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http://dx.doi.org/10.1016/j.parkreldis.2013.01.019DOI Listing
May 2013

In-vivo measurement of LDOPA uptake, dopamine reserve and turnover in the rat brain using [18F]FDOPA PET.

J Cereb Blood Flow Metab 2013 Jan 29;33(1):59-66. Epub 2012 Aug 29.

Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1038/jcbfm.2012.120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597374PMC
January 2013

The genetics of Parkinson's disease: progress and therapeutic implications.

Mov Disord 2013 Jan;28(1):14-23

Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1002/mds.25249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3578399PMC
January 2013

Subclinical signs in LRRK2 mutation carriers.

Parkinsonism Relat Disord 2011 Aug 8;17(7):528-32. Epub 2011 Jun 8.

Department of Neurology, St. Olav's University Hospital, Trondheim, Norway.

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http://linkinghub.elsevier.com/retrieve/pii/S135380201100108
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http://dx.doi.org/10.1016/j.parkreldis.2011.04.014DOI Listing
August 2011

A comparative study of Lrrk2 function in primary neuronal cultures.

Parkinsonism Relat Disord 2010 Dec 17;16(10):650-5. Epub 2010 Sep 17.

Division of Neurogenetics, Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2010.08.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159957PMC
December 2010

Dopamine turnover increases in asymptomatic LRRK2 mutations carriers.

Mov Disord 2010 Dec;25(16):2717-23

Department of Physics and Astronomy, University of British Columbia, Vancouver British Columbia, Canada.

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http://dx.doi.org/10.1002/mds.23356DOI Listing
December 2010

Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinson's disease.

Parkinsonism Relat Disord 2010 Dec 23;16(10):686-7. Epub 2010 Oct 23.

Division of Neurogenetics, Department of Neuroscience, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2010.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381965PMC
December 2010

Autonomic failures in Perry syndrome with DCTN1 mutation.

Parkinsonism Relat Disord 2010 Nov 11;16(9):612-4. Epub 2010 Aug 11.

Department of Neurology, Kokura Memorial Hospital, Fukuoka, Japan.

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http://dx.doi.org/10.1016/j.parkreldis.2010.07.001DOI Listing
November 2010