Matthew J Ellis

Matthew J Ellis

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Matthew J Ellis

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Clinical and Genomic Risk to Guide the Use of Adjuvant Therapy for Breast Cancer.

N Engl J Med 2019 06 3;380(25):2395-2405. Epub 2019 Jun 3.

From Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (J.A.S., D.F.M.); Dana-Farber Cancer Institute, Boston (R.J.G.); University of Texas, San Antonio (P.M.R.); Sunnybrook Research Institute, Toronto (K.I.P.), and McMaster University, Hamilton, ON (T.J.W.) - both in Canada; Loyola University Medical Center, Maywood (K.S.A.), and Northwestern University, Chicago (L.I.W., V.G.K.) - both in Illinois; University of Michigan, Ann Arbor (D.F.H.); Virginia Commonwealth University School of Medicine and the Massey Cancer Center, Richmond (C.E.G.); University of North Carolina, Chapel Hill (E.C.D.), and Duke University Medical Center, Durham (J.A.O., J.A.) - both in North Carolina; Mayo Clinic, Jacksonville, FL (M.P.G.); National Institutes of Health, National Cancer Institute, Bethesda, MD (T.L.); Indiana University School of Medicine (S.S.B.) and Indiana University Hospital (G.W.S.), Indianapolis; Vince Lombardi Cancer Clinic, Two Rivers (T.J.S.), and Fox Valley Hematology and Oncology, Appleton (T.F.G.) - both in Wisconsin; Washington University, St. Louis (M.J.E.); the National Surgical Adjuvant Breast and Bowel Project Pathology Office (S.P.) and the University of Pittsburgh (A.M.B.), Pittsburgh; Emory University, Atlanta (W.C.W.); Cancer Trials Ireland, Dublin (M.M.K.); Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru (H.L.G.M.); Cancer Center of Kansas, Wichita (P.S.R.); Vanderbilt University, Nashville (I.A.M.); Rutgers Cancer Institute of New Jersey, New Brunswick (D.L.T.); and the University of Hawaii Cancer Center, Honolulu (J.L.B.).

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http://dx.doi.org/10.1056/NEJMoa1904819DOI Listing
June 2019

MiRNAs and long-term breast cancer survival: Evidence from the WHEL Study.

Cancer Epidemiol Biomarkers Prev 2019 Jun 11. Epub 2019 Jun 11.

Moores Cancer Center, Center for Personalized Cancer Therapy A Division of Hematology and Oncology, UC San Diego.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-1322DOI Listing
June 2019

alterations and metastasis in estrogen receptor positive breast cancer.

J Cancer Metastasis Treat 2019 4;5. Epub 2019 May 4.

Interdepartmental Graduate Program in Translational Biology & Molecular Medicine, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.20517/2394-4722.2019.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519472PMC
May 2019

DNA damage repair defects as a new class of endocrine treatment resistance driver.

Oncotarget 2018 Nov 20;9(91):36252-36253. Epub 2018 Nov 20.

Svasti Haricharan: Department of Tumor Microenvironment and Cancer Immunology, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.

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http://dx.doi.org/10.18632/oncotarget.26363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284739PMC
November 2018

Comprehensive Profiling of DNA Repair Defects in Breast Cancer Identifies a Novel Class of Endocrine Therapy Resistance Drivers.

Clin Cancer Res 2018 Oct 23;24(19):4887-4899. Epub 2018 May 23.

Department of Medicine, Baylor College of Medicine, Houston, Texas.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-3702DOI Listing
October 2018

fusions drive endocrine therapy resistance and metastasis in breast cancer.

Mol Cell Oncol 2018 9;5(6):e1526005. Epub 2018 Oct 9.

Interdepartmental Graduate Program in Translational Biology & Molecular Medicine, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.1080/23723556.2018.1526005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276858PMC
October 2018

Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer.

N Engl J Med 2018 Jul 3;379(2):111-121. Epub 2018 Jun 3.

From Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (J.A.S., D.F.M.); Dana-Farber Cancer Institute, Boston (R.J.G.); Sunnybrook Research Institute, Toronto (K.I.P.), and McMaster University, Hamilton, ON (T.J.W.) - both in Canada; Loyola University Chicago Stritch School of Medicine, Maywood (K.S.A.), and Northwestern University, Chicago (L.I.W., V.G.K.) - both in Illinois; University of Michigan, Ann Arbor (D.F.H.); Virginia Commonwealth University School of Medicine and the Massey Cancer Center, Richmond (C.E.G.); University of North Carolina, Chapel Hill (E.C.D.), and Duke University Medical Center, Durham (J.A.O.) - both in North Carolina; Mayo Clinic, Jacksonville, FL (M.P.G.); National Institutes of Health, National Cancer Institute, Bethesda, MD (T.L., J.A.); Indiana University School of Medicine (S.S.B.) and Indiana University Hospital (G.W.S.), Indianapolis; Vince Lombardi Cancer Clinic, Two Rivers (T.J.S.), and Fox Valley Hematology and Oncology, Appleton (T.F.G.) - both in Wisconsin; Washington University, St. Louis (M.J.E.); National Surgical Adjuvant Breast and Bowel Project Pathology Office (S.P.) and University of Pittsburgh (A.M.B.), Pittsburgh; Emory University, Atlanta (W.C.W.); University of Texas, San Antonio (P.M.R.); Cancer Trials Ireland, Dublin (M.M.K.); Instituto Nacional de Enfermedades Neoplasicas, Lima, Peru (H.L.G.M.); Cancer Center of Kansas, Wichita (P.S.R.); Vanderbilt University, Nashville (I.A.M.); Rutgers Cancer Institute of New Jersey, New Brunswick (D.L.T.); and University of Hawaii Cancer Center, Honolulu (J.L.B.).

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http://www.nejm.org/doi/10.1056/NEJMoa1804710
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http://dx.doi.org/10.1056/NEJMoa1804710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172658PMC
July 2018

Endocrine therapy for ER-positive/HER2-negative metastatic breast cancer.

Chin Clin Oncol 2018 Jun;7(3):25

Instituto Nacional de Câncer (INCA-HCIII), Rio de Janeiro, Brazil.

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http://dx.doi.org/10.21037/cco.2018.06.06DOI Listing
June 2018

Current Status of Neoadjuvant Endocrine Therapy in Early Stage Breast Cancer.

Curr Treat Options Oncol 2018 04 16;19(5):23. Epub 2018 Apr 16.

Lester and Sue Smith Breast Cancer Center, Baylor College of Medicine, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s11864-018-0538-9DOI Listing
April 2018

Identifying biomarkers of breast cancer micrometastatic disease in bone marrow using a patient-derived xenograft mouse model.

Breast Cancer Res 2018 01 2;20(1). Epub 2018 Jan 2.

Department of Surgery, Washington University School of Medicine, 660 South Euclid Avenue, St. Louis, MO, 63110, USA.

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http://dx.doi.org/10.1186/s13058-017-0927-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748947PMC
January 2018

Cytoplasmic Cyclin E Mediates Resistance to Aromatase Inhibitors in Breast Cancer.

Clin Cancer Res 2017 Dec 25;23(23):7288-7300. Epub 2017 Sep 25.

Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://clincancerres.aacrjournals.org/lookup/doi/10.1158/107
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http://dx.doi.org/10.1158/1078-0432.CCR-17-1544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768442PMC
December 2017

Avoidance of Negative Results in Adjuvant Endocrine Therapy Trials for Estrogen Receptor-Positive Breast Cancer.

J Clin Oncol 2017 08 5;35(23):2718-2719. Epub 2017 Jun 5.

Rodrigo Goncalves, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Tomás Reinert, Hospital do Câncer Mãe de Deus, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil; and Matthew J. Ellis, Baylor College of Medicine, Houston, TX.

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http://dx.doi.org/10.1200/JCO.2017.73.0424DOI Listing
August 2017

Lessons in precision oncology from neoadjuvant endocrine therapy trials in ER+ breast cancer.

Authors:
Matthew J Ellis

Breast 2017 Aug 30;34 Suppl 1:S104-S107. Epub 2017 Jun 30.

Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.breast.2017.06.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592154PMC
August 2017

Defects in mismatch repair: the Achilles heel of estrogen receptor positive breast cancer with intrinsic endocrine therapy resistance?

Oncoscience 2017 Jul 21;4(7-8):77-78. Epub 2017 Sep 21.

Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.

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http://dx.doi.org/10.18632/oncoscience.363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616200PMC
July 2017

Ki67 Proliferation Index as a Tool for Chemotherapy Decisions During and After Neoadjuvant Aromatase Inhibitor Treatment of Breast Cancer: Results From the American College of Surgeons Oncology Group Z1031 Trial (Alliance).

J Clin Oncol 2017 Apr 3;35(10):1061-1069. Epub 2017 Jan 3.

Matthew J. Ellis and Chad J. Creighton, Baylor College of Medicine; Gildy Babiera and Kelly Hunt, MD Anderson Cancer Center, Houston; Gary Unzeitig, Doctor's Hospital of Laredo, Laredo; Marilyn Leitch, University of Texas Southwestern Campus, Dallas, TX; Vera J. Suman, Mayo Clinic, Rochester MN; Jeremy Hoog, Rodrigo Goncalves, Souzan Sanati, Katherine DeSchryver, Erika Crouch, Amy Brink, Mark Watson, Jingqin Luo, Yu Tao, Cynthia X. Ma, and D. Craig Allred, Washington University School of Medicine, St Louis; Timothy Pluard, St Lukes Hospital, Kansas City, MO; Michael Barnes, Roche Diagnostics, Mountain View; Laura Esserman, University of California San Francisco, San Francisco, CA; Mitchell Dowsett, Royal Marsden Hospital, London, UK; G. Thomas Budd, Cleveland Clinic; Paula Silverman, Case Western Reserve University, Cleveland OH; Eric Winer, Dana-Farber Cancer Institute, Boston MA; Lisa Carey, University of North Carolina, Chapel Hill; David Ota, Duke University, Durham, NC; Pat Whitworth, Nashville Breast Center, Nashville, TN; J. Michael Guenther, St Elizabeth Medical Center, Edgewood, KY; Zoneddy Dayao, University of New Mexico, Albuquerque, NM; and John A. Olson Jr, University of Maryland School of Medicine and Greenebaum Cancer Center, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2016.69.4406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455353PMC
April 2017

Reactivation of p53 by MDM2 Inhibitor MI-77301 for the Treatment of Endocrine-Resistant Breast Cancer.

Mol Cancer Ther 2016 12 7;15(12):2887-2893. Epub 2016 Oct 7.

Department of Internal Medicine, University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1158/1535-7163.MCT-16-0028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367629PMC
December 2016

Reply: Can Dead Space Ventilation Really Be Measured without Pa?

Am J Respir Crit Care Med 2016 12;194(12):1556-1557

1 The Alfred Melbourne, Victoria, Australia and.

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http://dx.doi.org/10.1164/rccm.201607-1336LEDOI Listing
December 2016

Reply: Dyspnea in Heart Failure: A Multiheaded Beast.

Am J Respir Crit Care Med 2016 09;194(6):775-6

1 The Alfred Melbourne, Victoria, Australia and.

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http://dx.doi.org/10.1164/rccm.201604-0837LEDOI Listing
September 2016

Prognostic and Predictive Biomarkers of Endocrine Responsiveness for Estrogen Receptor Positive Breast Cancer.

Adv Exp Med Biol 2016 ;882:125-54

Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, 320A Cullen, MS 600, 77030, Houston, TX, USA.

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http://dx.doi.org/10.1007/978-3-319-22909-6_5DOI Listing
August 2016

Phase III Trial Evaluating Letrozole As First-Line Endocrine Therapy With or Without Bevacizumab for the Treatment of Postmenopausal Women With Hormone Receptor-Positive Advanced-Stage Breast Cancer: CALGB 40503 (Alliance).

J Clin Oncol 2016 08 2;34(22):2602-9. Epub 2016 May 2.

Maura N. Dickler, Mary Ellen Moynahan, Diana E. Lake, and Clifford A. Hudis, Memorial Sloan Kettering Cancer Center, New York, NY; William T. Barry, Dana-Farber Cancer Institute; Eric P. Winer, Dana-Farber/Partners Cancer Care, Boston, MA; Constance T. Cirrincione, Duke University, Durham, NC; Matthew J. Ellis, Baylor College of Medicine; Debasish Tripathy, The University of Texas MD Anderson Cancer Center, Houston, TX; Federico Innocenti and Lisa A. Carey, University of North Carolina at Chapel Hill, Chapel Hill, NC; Arti Hurria, City of Hope, Duarte; Hope S. Rugo, University of California at San Francisco, San Francisco, CA; Olwen Hahn, Alliance for Clinical Trials in Oncology, Chicago, IL; and Bryan P. Schneider, Indiana University School of Medicine, Indianapolis, IN.

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http://dx.doi.org/10.1200/JCO.2015.66.1595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012690PMC
August 2016

Increased Dead Space Ventilation Mediates Reduced Exercise Capacity in Systolic Heart Failure.

Am J Respir Crit Care Med 2016 06;193(11):1292-300

1 Department of Allergy, Immunology and Respiratory Medicine, The Alfred, Prahran, Victoria, Australia; and.

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http://dx.doi.org/10.1164/rccm.201508-1555OCDOI Listing
June 2016

Reply to T. Reinert et al.

J Clin Oncol 2016 06 21;34(16):1960-1. Epub 2016 Mar 21.

University of Nottingham, Derby, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2016.66.6727DOI Listing
June 2016

Maximal exercise does not increase ventilation heterogeneity in healthy trained adults.

Physiol Rep 2016 Apr;4(7)

Department of Medicine, Monash University, Melbourne, Australia Allergy, Immunology & Respiratory Medicine, The Alfred, Melbourne, Australia.

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http://dx.doi.org/10.14814/phy2.12747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831321PMC
April 2016

QuantFusion: Novel Unified Methodology for Enhanced Coverage and Precision in Quantifying Global Proteomic Changes in Whole Tissues.

Mol Cell Proteomics 2016 Feb 23;15(2):740-51. Epub 2015 Nov 23.

From the ‡Department of Biochemistry and Biophysics, §Lineberger Comprehensive Cancer Center, and

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http://dx.doi.org/10.1074/mcp.O115.049791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739686PMC
February 2016

Application of a Novel CT-Based Iliac Artery Calcification Scoring System for Predicting Renal Transplant Outcomes.

AJR Am J Roentgenol 2016 Feb;206(2):436-41

1 Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710.

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http://dx.doi.org/10.2214/AJR.15.14794DOI Listing
February 2016

Integrated Bottom-Up and Top-Down Proteomics of Patient-Derived Breast Tumor Xenografts.

Mol Cell Proteomics 2016 Jan 26;15(1):45-56. Epub 2015 Oct 26.

From the ‡Proteomics Center of Excellence, §Department of Chemistry, and ¶Department of Molecular BiosciencesNorthwestern University, Evanston, IL 60208;

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http://dx.doi.org/10.1074/mcp.M114.047480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762530PMC
January 2016

Fulvestrant 500 mg Versus Anastrozole 1 mg for the First-Line Treatment of Advanced Breast Cancer: Overall Survival Analysis From the Phase II FIRST Study.

J Clin Oncol 2015 Nov 14;33(32):3781-7. Epub 2015 Sep 14.

Matthew J. Ellis, Baylor College of Medicine, Houston, TX; Antonio Llombart-Cussac, Hospital Arnau de Vilanova, Lérida, Spain; David Feltl, FNsP Ostrava, Ostrava-Poruba, Czech Republic; John A. Dewar, Ninewells Hospital and Medical School, Dundee; Nicola Hewson and Yuri Rukazenkov, AstraZeneca Pharmaceuticals, Macclesfield; John F.R. Robertson, University of Nottingham, Derby, United Kingdom; and Marek Jasiówka, Instytut im Marii Skłodowskiej-Curie, Kraków, Poland.

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http://dx.doi.org/10.1200/JCO.2015.61.5831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737861PMC
November 2015

Prospective Validation of a 21-Gene Expression Assay in Breast Cancer.

N Engl J Med 2015 Nov 27;373(21):2005-14. Epub 2015 Sep 27.

From the Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY (J.A.S., D.F.M.); Dana-Farber Cancer Institute, Boston (R.J.G.); Sunnybrook Research Institute, Toronto (K.I.P.) and Juravinski Cancer Center, Hamilton, ON (T.J.W.) - both in Canada; Loyola University Medical Center, Maywood (K.S.A.), and Northwestern University, Chicago (L.I.W., V.G.K.) - both in Illinois; University of Michigan, Ann Arbor (D.F.H.); Virginia Commonwealth University School of Medicine and the Massey Cancer Center, Richmond (C.E.G.); University of North Carolina, Chapel Hill (E.C.D.), Duke University Medical Center, Durham (J.A.O.), Wake Forest University Health Service, Winston-Salem (L.I.W.), and Southeast Clinical Oncology Research Consortium, Goldsboro (J.N.A.) - all in North Carolina; Mayo Clinic, Jacksonville, FL (E.A.P.); University of Maryland School of Medicine, Baltimore (J.A.O.), and National Institutes of Health, Bethesda (J.Z., T.L.) - both in Maryland; Indiana University School of Medicine (S.S.B.) and Indiana University Hospital (G.W.S.) - both in Indianapolis; Vince Lombardi Cancer Clinic, Two Rivers (T.J.S.), and Fox Valley Hematology and Oncology, Appleton (T.F.G.) - both in Wisconsin; Baylor College of Medicine, Houston (M.J.E.), and University of Texas, San Antonio (P.R.) - both in Texas; Washington University, St. Louis (M.J.E.); Allegheny General Hospital (S.P.) and University of Pittsburgh (A.M.B.) - both in Pittsburgh; the Department of Medical Oncology and Breast Center, Yonsei University College of Medicine, Seoul, South Korea (S.P.); Emory University, Atlanta (W.C.W.); Irish Clinical Oncology Research Group, Dublin (M.M.K.); Instituto Nacional de Enfermedades Neoplásicas, Lima, Peru (H.L.G.M.); Cancer Center of Kansas, Wichita (P.S.R.); Vanderbilt University, Nashville (I.A.M.); Rutgers Cancer Institute of New Jersey, New Brunswick (D.L.T.); University of Hawaii Cancer Center, Honolulu (J.L.B.); and Stanford University, Stanford, CA (G.W.S.)

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http://dx.doi.org/10.1056/NEJMoa1510764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701034PMC
November 2015

Early bronchiolitis obliterans syndrome shows an abnormality of perfusion not ventilation in lung transplant recipients.

Respir Physiol Neurobiol 2015 Sep 14;216:28-34. Epub 2015 May 14.

Departments of Medicine and Radiology University of California, La Jolla, San Diego, CA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15699048150010
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http://dx.doi.org/10.1016/j.resp.2015.05.003DOI Listing
September 2015

HER2-Mutated Breast Cancer Responds to Treatment With Single-Agent Neratinib, a Second-Generation HER2/EGFR Tyrosine Kinase Inhibitor.

J Natl Compr Canc Netw 2015 Sep;13(9):1061-4

From the Department of Oncology, Kaplan Medical Center, Rehovot, Israel; Section of Breast Oncology, Division of Oncology, Department of Medicine, Siteman Cancer Center, and Washington University School of Medicine, St. Louis, Missouri; and Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas. From the Department of Oncology, Kaplan Medical Center, Rehovot, Israel; Section of Breast Oncology, Division of Oncology, Department of Medicine, Siteman Cancer Center, and Washington University School of Medicine, St. Louis, Missouri; and Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas. From the Department of Oncology, Kaplan Medical Center, Rehovot, Israel; Section of Breast Oncology, Division of Oncology, Department of Medicine, Siteman Cancer Center, and Washington University School of Medicine, St. Louis, Missouri; and Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas.

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http://www.jnccn.org/content/13/9/1061.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701428PMC
September 2015

New concepts in breast cancer genomics and genetics.

Breast Cancer Res 2014 ;16(5):460

Breast Cancer Program, Department of Medical Oncology, Washington University School of Medicine, 660 S. Euclid Ave, St Louis 63110, MO, USA; Siteman Cancer Center, Washington University School of Medicine, 660 S. Euclid Ave, St Louis 63110, MO, USA; Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, 320A Cullen MS600, Houston 77030, TX, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384360PMC
July 2015

US breast cancer mortality trends in young women according to race.

Cancer 2015 May 5;121(9):1469-76. Epub 2014 Dec 5.

Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St. Louis, Missouri.

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http://dx.doi.org/10.1002/cncr.29178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409464PMC
May 2015

Mechanisms of aromatase inhibitor resistance.

Nat Rev Cancer 2015 May;15(5):261-75

Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston 77030, Texas, USA.

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http://dx.doi.org/10.1038/nrc3920DOI Listing
May 2015

Defining breast cancer intrinsic subtypes by quantitative receptor expression.

Oncologist 2015 May 23;20(5):474-82. Epub 2015 Apr 23.

Lineberger Comprehensive Cancer Center and Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA; Clinical Trials and Statistics Unit at The Institute of Cancer Research, London, United Kingdom; Servicio de Oncología Médica, Instituto de Investigacion Sanitaria Hospital Universitario Gregorio Marañón, Facultad de Medicina, Universidad Complutense, Madrid, Spain; Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada; Translation Genomics Unit, Vall d´Hebron Institute of Oncology, Barcelona, Spain; British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Department of Medical Oncology, Hospital General Universitario de Elche, Alicante, Spain; Department of Medical Oncology, Instituto Valenciano de Oncologia, Valencia, Spain; National Cancer Institute of Canada Clinical Trials Group, Kingston, Ontario, Canada; Department of Medical Oncology, Hospital Universitario Virgen del Rocio, Seville, Spain; Department of Medical Oncology, Complejo Hospitalario Universitario A Coruña, Coruña, Spain; Department of Medical Oncology, Hospital Universitario Virgen de la Victoria, Málaga, Spain; GEICAM, Madrid, Spain; Sunnybrook Odette Cancer Centre, University of Toronto, Toronto, Ontario, Canada; McMaster University, Hamilton, Ontario, Canada; Department of Oncology, Tom Baker Cancer Centre, University of Calgary, Calgary, Alberta, Canada; Department of Pathology, University of Utah Health Sciences Center, Salt Lake City, Utah, USA; Department of Medicine, Washington University, St. Louis, Missouri, USA; Department of Oncology, Hospital of Prato, Istituto Toscani Tumori, Florence, Italy

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http://dx.doi.org/10.1634/theoncologist.2014-0372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4425383PMC
May 2015

Detailed characterization of a long-term rodent model of critical illness and recovery.

Crit Care Med 2015 Mar;43(3):e84-96

1Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, London, United Kingdom. 2Academic Department of Military Medicine, Royal Centre for Defence Medicine, Birmingham, United Kingdom. 3Section of Investigative Medicine, Imperial College London, London, United Kingdom. 4Division of Neuropathology, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, United Kingdom. 5Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom. 6Dubowitz Neuromuscular Centre and MRC Centre for Neuromuscular Disorders, University College London Institute of Child Health and Great Ormond Street Hospital for Children, London, United Kingdom. 7Laboratoire de Physiologie de l'Exercice, Université de Lyon, Saint Etienne, France. 8Centre for Perioperative Medicine and Critical Care Research, Imperial College Healthcare NHS Trust, London, United Kingdom.

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http://dx.doi.org/10.1097/CCM.0000000000000854DOI Listing
March 2015

Outcomes in kidney transplant recipients from older living donors.

Transplantation 2015 Feb;99(2):309-15

1 Department of Surgery, Duke University Medical Center, Durham, NC. 2 Duke Clinical Research Institute, Durham, NC. 3 CTI, Clinical Trial and Consulting Services, Raleigh, NC. 4 Division of Abdominal Transplantation, Duke University Medical Center, Durham, NC. 5 Department of Medicine, Division of Nephrology, Duke University Medical Center, Durham, NC.

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http://dx.doi.org/10.1097/TP.0000000000000607DOI Listing
February 2015

Treatment-associated musculoskeletal and vasomotor symptoms and relapse-free survival in the NCIC CTG MA.27 adjuvant breast cancer aromatase inhibitor trial.

J Clin Oncol 2015 Jan 15;33(3):265-71. Epub 2014 Dec 15.

Vered Stearns, Kimmel Cancer Center, Johns Hopkins, Baltimore, MD; Judith-Anne W. Chapman, Aurélie Le Maitre, Jessica Kundapur, and Lois E. Shepherd, NCIC Clinical Trials Group, Queen's University, Kingston; Kathleen I. Pritchard, Sunnybrook Odette Cancer Centre and University of Toronto, Toronto, Ontario, Canada; Cynthia X. Ma, Siteman Cancer Center, Washington University, St Louis, MO; Matthew J. Ellis, Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX; James N. Ingle, Mayo Clinic, Rochester, MN; G. Thomas Budd, Cleveland Clinic, Cleveland, OH; George W. Sledge, Stanford University, San Francisco, CA; Pedro E.R. Liedke and Paul E. Goss, Harvard University; Paul E. Goss, Avon International Breast Cancer Research Program, Massachusetts General Hospital, Boston, MA; Manuela Rabaglio, Inselspital University Hospital and International Breast Cancer Study Group Coordinating Center, Berne, Switzerland; and Pedro E.R. Liedke, Hospital de Clínicas de Porto Alegre and Instituto do Cancer Mãe de Deus, Oncologia, Porto Alegre, Rio Grande do Sul, Brazil.

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http://jco.ascopubs.org/content/33/3/265.full.pdf
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.57.6926
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http://dx.doi.org/10.1200/JCO.2014.57.6926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289722PMC
January 2015

Estrogen receptor expression is high but is of lower intensity in tubular carcinoma than in well-differentiated invasive ductal carcinoma.

Arch Pathol Lab Med 2014 Nov;138(11):1507-13

From the Department of Pathology (Drs Jorns and Thomas) and Comprehensive Cancer Center (Mr Healy and Ms Daignault), University of Michigan, Ann Arbor; the Genome Institute (Ms Vickery and Dr Mardis) and Division of Oncology (Ms Snider and Drs Davies and Ellis), Washington University School of Medicine, St Louis, Missouri; and the Department of Laboratory Medicine and Pathology (Dr Visscher), Mayo Medical Laboratories, Rochester, Minnesota.

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http://dx.doi.org/10.5858/arpa.2013-0621-OADOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4327939PMC
November 2014

Aromatase inhibitor-associated bone fractures: a case-cohort GWAS and functional genomics.

Mol Endocrinol 2014 Oct 22;28(10):1740-51. Epub 2014 Aug 22.

Division of Clinical Pharmacology (M.L., L.W., R.M.W.), Department of Molecular Pharmacology and Experimental Therapeutics; Departments of Oncology (J.N.I.) and Health Sciences Research (A.B., G.D.J., E.E.C., D.J.S.); and Division of Endocrinology (S.K.), Mayo Clinic, Rochester, Minnesota 55905; Massachusetts General Hospital (P.E.G.), Harvard University, Boston, Massachusetts 02114; Rikagaku Kenkyūsho Center for Integrative Medical Science (M.K., Y.F.), Yokohama, Japan 230-0045; School of Medicine (Y.N.), Chicago University, Chicago, Illinois 60637; National Cancer Institute of Canada Clinical Trials Group (J.-A.W.C., L.E.S.), Kingston, Ontario, Canada K7L 3N6; and Division of Oncology (M.J.E.), Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110.

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http://dx.doi.org/10.1210/me.2014-1147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179631PMC
October 2014

Loss of Trop2 causes ErbB3 activation through a neuregulin-1-dependent mechanism in the mesenchymal subtype of HNSCC.

Oncotarget 2014 Oct;5(19):9281-94

Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St. Louis, Missouri. The Alvin J. Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253434PMC
http://dx.doi.org/10.18632/oncotarget.2423DOI Listing
October 2014

Proteogenomic characterization of human colon and rectal cancer.

Nature 2014 Sep 20;513(7518):382-7. Epub 2014 Jul 20.

1] Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA [2] Jim Ayers Institute for Precancer Detection and Diagnosis, Vanderbilt-Ingram Cancer Center, Nashville, Tennessee 37232, USA.

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http://dx.doi.org/10.1038/nature13438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249766PMC
September 2014

SciClone: inferring clonal architecture and tracking the spatial and temporal patterns of tumor evolution.

PLoS Comput Biol 2014 Aug 7;10(8):e1003665. Epub 2014 Aug 7.

The Genome Institute, Washington University, St. Louis, Missouri, United States of America; Department of Internal Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, Missouri, United States of America; Department of Genetics, Washington University, St. Louis, Missouri, United States of America; Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1003665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125065PMC
August 2014

Tacrolimus dose requirements in African-American and Caucasian kidney transplant recipients on mycophenolate and prednisone.

Clin Transplant 2014 Jul 23;28(7):762-7. Epub 2014 May 23.

Department of Pharmacy, Duke University Health System, Durham, NC, USA.

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http://dx.doi.org/10.1111/ctr.12376DOI Listing
July 2014

The Cancer Genome Atlas: clinical applications for breast cancer.

Oncology (Williston Park) 2013 Dec;27(12):1263-9, 1274-9

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December 2013