Publications by authors named "Matthew G Rees"

20Publications

Computational Analyses Connect Small-Molecule Sensitivity to Cellular Features Using Large Panels of Cancer Cell Lines.

Methods Mol Biol 2019 ;1888:233-254

Chemical Biology and Therapeutics Science Program, Broad Institute of Harvard and MIT, Cambridge, MA, USA.

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http://link.springer.com/10.1007/978-1-4939-8891-4_14
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http://dx.doi.org/10.1007/978-1-4939-8891-4_14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6563933PMC
June 2019

Discovery of a Small-Molecule Probe for V-ATPase Function.

J Am Chem Soc 2015 Apr 20;137(16):5563-8. Epub 2015 Apr 20.

∥Center for Computational and Integrative Biology, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114, United States.

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http://dx.doi.org/10.1021/jacs.5b02150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416280PMC
April 2015

Glucokinase regulatory protein: complexity at the crossroads of triglyceride and glucose metabolism.

Curr Opin Lipidol 2015 Apr;26(2):88-95

aOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK bCenter for the Science of Therapeutics, Broad Institute cHoward Hughes Medical Institute, Broad Institute, Cambridge, Massachusetts, USA dNIHR Oxford Biomedical Research Centre, ORH Trust, OCDEM, Churchill Hospital, Oxford, UK.

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http://dx.doi.org/10.1097/MOL.0000000000000155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422901PMC
April 2015

NAMPT is the cellular target of STF-31-like small-molecule probes.

ACS Chem Biol 2014 Oct 7;9(10):2247-54. Epub 2014 Aug 7.

Center for the Science of Therapeutics and ∥Howard Hughes Medical Institute, Broad Institute , 7 Cambridge Center, Cambridge, Massachusetts 02142, United States.

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http://dx.doi.org/10.1021/cb500347pDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201331PMC
October 2014

Inheritance of rare functional GCKR variants and their contribution to triglyceride levels in families.

Hum Mol Genet 2014 Oct 30;23(20):5570-8. Epub 2014 May 30.

Oxford Centre for Diabetes, Endocrinology & Metabolism, University of Oxford, Oxford OX3 7LE, UK, NIHR Oxford Biomedical Research Centre, ORH Trust, OCDEM, Churchill Hospital, Oxford OX3 7LE, UK

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
Publisher Site
http://dx.doi.org/10.1093/hmg/ddu269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168830PMC
October 2014

Small molecular glucokinase activators: has another new anti-diabetic therapeutic lost favour?

Br J Pharmacol 2013 Jan;168(2):335-8

Oxford Centre for Diabetes Endocrinology & Metabolism, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1111/j.1476-5381.2012.02201.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3572560PMC
January 2013

Six new loci associated with body mass index highlight a neuronal influence on body weight regulation.

Authors:
Cristen J Willer Elizabeth K Speliotes Ruth J F Loos Shengxu Li Cecilia M Lindgren Iris M Heid Sonja I Berndt Amanda L Elliott Anne U Jackson Claudia Lamina Guillaume Lettre Noha Lim Helen N Lyon Steven A McCarroll Konstantinos Papadakis Lu Qi Joshua C Randall Rosa Maria Roccasecca Serena Sanna Paul Scheet Michael N Weedon Eleanor Wheeler Jing Hua Zhao Leonie C Jacobs Inga Prokopenko Nicole Soranzo Toshiko Tanaka Nicholas J Timpson Peter Almgren Amanda Bennett Richard N Bergman Sheila A Bingham Lori L Bonnycastle Morris Brown Noël P Burtt Peter Chines Lachlan Coin Francis S Collins John M Connell Cyrus Cooper George Davey Smith Elaine M Dennison Parimal Deodhar Paul Elliott Michael R Erdos Karol Estrada David M Evans Lauren Gianniny Christian Gieger Christopher J Gillson Candace Guiducci Rachel Hackett David Hadley Alistair S Hall Aki S Havulinna Johannes Hebebrand Albert Hofman Bo Isomaa Kevin B Jacobs Toby Johnson Pekka Jousilahti Zorica Jovanovic Kay-Tee Khaw Peter Kraft Mikko Kuokkanen Johanna Kuusisto Jaana Laitinen Edward G Lakatta Jian'an Luan Robert N Luben Massimo Mangino Wendy L McArdle Thomas Meitinger Antonella Mulas Patricia B Munroe Narisu Narisu Andrew R Ness Kate Northstone Stephen O'Rahilly Carolin Purmann Matthew G Rees Martin Ridderstråle Susan M Ring Fernando Rivadeneira Aimo Ruokonen Manjinder S Sandhu Jouko Saramies Laura J Scott Angelo Scuteri Kaisa Silander Matthew A Sims Kijoung Song Jonathan Stephens Suzanne Stevens Heather M Stringham Y C Loraine Tung Timo T Valle Cornelia M Van Duijn Karani S Vimaleswaran Peter Vollenweider Gerard Waeber Chris Wallace Richard M Watanabe Dawn M Waterworth Nicholas Watkins Jacqueline C M Witteman Eleftheria Zeggini Guangju Zhai M Carola Zillikens David Altshuler Mark J Caulfield Stephen J Chanock I Sadaf Farooqi Luigi Ferrucci Jack M Guralnik Andrew T Hattersley Frank B Hu Marjo-Riitta Jarvelin Markku Laakso Vincent Mooser Ken K Ong Willem H Ouwehand Veikko Salomaa Nilesh J Samani Timothy D Spector Tiinamaija Tuomi Jaakko Tuomilehto Manuela Uda André G Uitterlinden Nicholas J Wareham Panagiotis Deloukas Timothy M Frayling Leif C Groop Richard B Hayes David J Hunter Karen L Mohlke Leena Peltonen David Schlessinger David P Strachan H-Erich Wichmann Mark I McCarthy Michael Boehnke Inês Barroso Gonçalo R Abecasis Joel N Hirschhorn

Nat Genet 2009 Jan 14;41(1):25-34. Epub 2008 Dec 14.

Genetic Investigation of ANthropometric Traits Consortium.

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http://dx.doi.org/10.1038/ng.287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695662PMC
January 2009