Matthew B Soellner

Matthew B Soellner

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Matthew B Soellner

Matthew B Soellner

Publications by authors named "Matthew B Soellner"

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31Publications

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Selective Proteolysis to Study the Global Conformation and Regulatory Mechanisms of c-Src Kinase.

ACS Chem Biol 2019 Jul 9;14(7):1556-1563. Epub 2019 Jul 9.

Department of Internal Medicine , University of Michigan , Ann Arbor , Michigan 48109 , United States.

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http://dx.doi.org/10.1021/acschembio.9b00306DOI Listing
July 2019

IL-4/IL-13 Stimulated Macrophages Enhance Breast Cancer Invasion Via Rho-GTPase Regulation of Synergistic VEGF/CCL-18 Signaling.

Front Oncol 2019 31;9:456. Epub 2019 May 31.

Department of Internal Medicine, Hematology-Oncology, Rogel Cancer Center, University of Michigan, Ann Arbor, MI, United States.

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http://dx.doi.org/10.3389/fonc.2019.00456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554436PMC
May 2019

Bivalent Inhibitors of c-Src Tyrosine Kinase That Bind a Regulatory Domain.

Bioconjug Chem 2016 Jul 22;27(7):1745-9. Epub 2016 Jun 22.

Departments of Medicinal Chemistry and ‡Chemistry, University of Michigan , Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/acs.bioconjchem.6b00243DOI Listing
July 2016

Conformation-Selective Analogues of Dasatinib Reveal Insight into Kinase Inhibitor Binding and Selectivity.

ACS Chem Biol 2016 05 1;11(5):1296-304. Epub 2016 Mar 1.

Department of Pharmacological Sciences, Stony Brook University , Stony Brook, New York 11794, United States.

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http://dx.doi.org/10.1021/acschembio.5b01018DOI Listing
May 2016

Synthesis and Biological Evaluation of Lactimidomycin and Its Analogues.

Chemistry 2015 Dec 18;21(52):19159-67. Epub 2015 Nov 18.

Department of Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, MI 48109-1055 (USA).

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http://sciforum.net/conference/ecsoc-17/paper/2299/download/
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http://doi.wiley.com/10.1002/chem.201503527
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http://dx.doi.org/10.1002/chem.201503527DOI Listing
December 2015

Discovery of Bivalent Kinase Inhibitors via Enzyme-Templated Fragment Elaboration.

ACS Med Chem Lett 2015 Aug 13;6(8):898-901. Epub 2015 Jul 13.

Departments of Medicinal Chemistry and Chemistry, University of Michigan , 930 North University Avenue, Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/acsmedchemlett.5b00167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538437PMC
August 2015

Exquisitely specific bisubstrate inhibitors of c-Src kinase.

ACS Chem Biol 2015 Jun 31;10(6):1387-91. Epub 2015 Mar 31.

†Department of Medicinal Chemistry and ‡Department of Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/cb501048bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578647PMC
June 2015

Small molecule substrate phosphorylation site inhibitors of protein kinases: approaches and challenges.

ACS Chem Biol 2015 Jan 23;10(1):175-89. Epub 2014 Dec 23.

Department of Medicinal Chemistry and ‡Department of Chemistry, University of Michigan , 930 N. University Avenue, Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/cb5008376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301090PMC
January 2015

Substrate activity screening with kinases: discovery of small-molecule substrate-competitive c-Src inhibitors.

Angew Chem Int Ed Engl 2014 Jul 2;53(27):7010-3. Epub 2014 May 2.

Departments of Medicinal Chemistry and Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, MI 48109 (USA).

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http://dx.doi.org/10.1002/anie.201311096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108202PMC
July 2014

Modulating noncatalytic function with kinase inhibitors.

Chem Biol 2014 May;21(5):569-71

Departments of Medicinal Chemistry & Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, MI 48109, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10745521140015
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http://dx.doi.org/10.1016/j.chembiol.2014.05.005DOI Listing
May 2014

Enzyme-triggered gelation: targeting proteases with internal cleavage sites.

Chem Commun (Camb) 2014 Feb;50(14):1691-3

Department of Chemistry and Macromolecular Science and Engineering Program, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan, 48109-1055, USA.

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http://dx.doi.org/10.1039/c3cc48132hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143987PMC
February 2014

Activation state-selective kinase inhibitor assay based on ion mobility-mass spectrometry.

Anal Chem 2013 Aug 23;85(15):6995-7002. Epub 2013 Jul 23.

Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/ac4012655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784979PMC
August 2013

Development of a chimeric c-Src kinase and HDAC inhibitor.

ACS Med Chem Lett 2013 Aug;4(8):779-783

Department of Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, Michigan 48109, United States.

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http://dx.doi.org/10.1021/ml400175dDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3763859PMC
August 2013

Irreversible inhibitors of c-Src kinase that target a nonconserved cysteine.

ACS Chem Biol 2012 Nov 5;7(11):1910-7. Epub 2012 Sep 5.

Department of Medicinal Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, Michigan 48109, United States.

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ftp://50-201-185-115-static.hfc.comcastbusiness.net/BrettW/I
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http://pubs.acs.org/doi/abs/10.1021/cb300337u
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http://dx.doi.org/10.1021/cb300337uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500393PMC
November 2012

Development of a highly selective c-Src kinase inhibitor.

ACS Chem Biol 2012 Aug 4;7(8):1393-8. Epub 2012 Jun 4.

Department of Medicinal Chemistry, University of Michigan, 930 N. University Avenue, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1021/cb300172eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3423592PMC
August 2012

A general method for detecting protease activity via gelation and its application to artificial clotting.

Chem Commun (Camb) 2012 Jun 27;48(44):5482-4. Epub 2012 Apr 27.

Department of Medicinal Chemistry, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan, 48109-1055, USA.

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http://dx.doi.org/10.1039/c2cc31537hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376645PMC
June 2012

Electronic and steric effects on the rate of the traceless Staudinger ligation.

Org Biomol Chem 2008 Apr 3;6(7):1173-5. Epub 2008 Mar 3.

Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://xlink.rsc.org/?DOI=b802336k
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http://dx.doi.org/10.1039/b802336kDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2715360PMC
April 2008

Protein prosthesis: 1,5-disubstituted[1,2,3]triazoles as cis-peptide bond surrogates.

J Am Chem Soc 2007 Oct 3;129(42):12670-1. Epub 2007 Oct 3.

Department of Chemistry and Biochemistry, University of Wisconsin, Madison, WI 53706, USA.

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http://pubs.acs.org/doi/abs/10.1021/ja075865s
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http://dx.doi.org/10.1021/ja075865sDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2531141PMC
October 2007

Water-soluble phosphinothiols for traceless staudinger ligation and integration with expressed protein ligation.

J Am Chem Soc 2007 Sep 22;129(37):11421-30. Epub 2007 Aug 22.

Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://pubs.acs.org/doi/abs/10.1021/ja073204p
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http://dx.doi.org/10.1021/ja073204pDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851833PMC
September 2007

Fragment-based substrate activity screening method for the identification of potent inhibitors of the Mycobacterium tuberculosis phosphatase PtpB.

J Am Chem Soc 2007 Aug 18;129(31):9613-5. Epub 2007 Jul 18.

Department of Chemistry, University of California, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1021/ja0727520DOI Listing
August 2007

Human glycinamide ribonucleotide transformylase: active site mutants as mechanistic probes.

Biochemistry 2007 Jan;46(1):156-63

Division of Pharmaceutical Sciences, College of Pharmacy, University of Cincinnati Medical Center, P.O. Box 670004, Cincinnati, Ohio 45267, USA.

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http://dx.doi.org/10.1021/bi0619270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518408PMC
January 2007

Staudinger ligation of peptides at non-glycyl residues.

J Org Chem 2006 Dec;71(26):9824-30

Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1021/jo0620056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2565276PMC
December 2006

Reaction mechanism and kinetics of the traceless Staudinger ligation.

J Am Chem Soc 2006 Jul;128(27):8820-8

Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1021/ja060484kDOI Listing
July 2006

Chemical synthesis of proteins.

Annu Rev Biophys Biomol Struct 2005 ;34:91-118

Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1146/annurev.biophys.34.040204.144700DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845543PMC
July 2005

Synthetic surfaces for ribonuclease adsorption.

Langmuir 2005 Jan;21(1):187-90

Department of Biochemistry and Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1021/la0480686DOI Listing
January 2005

Site-specific protein immobilization by Staudinger ligation.

J Am Chem Soc 2003 Oct;125(39):11790-1

Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1021/ja036712hDOI Listing
October 2003

Potent inhibition of ribonuclease A by oligo(vinylsulfonic acid).

J Biol Chem 2003 Jun 20;278(23):20934-8. Epub 2003 Mar 20.

Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1074/jbc.M301852200DOI Listing
June 2003

Protein assembly by orthogonal chemical ligation methods.

J Am Chem Soc 2003 May;125(18):5268-9

Department of Chemistry, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1021/ja029752eDOI Listing
May 2003

Tandem cytochrome P450 monooxygenase genes and splice variants in the white rot fungus Phanerochaete chrysosporium: cloning, sequence analysis, and regulation of differential expression.

Fungal Genet Biol 2003 Feb;38(1):10-21

Molecular Toxicology Division, Department of Environmental Health, College of Medicine, University of Cincinnati, Cincinnati, OH 45267-0056, USA.

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February 2003

Staudinger ligation of alpha-azido acids retains stereochemistry.

J Org Chem 2002 Jul;67(14):4993-6

Department of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1021/jo025631lDOI Listing
July 2002