Publications by authors named "Matteo Pellegrini"

100Publications

Extracellular traps released by antimicrobial TH17 cells contribute to host defense.

J Clin Invest 2020 Nov 19. Epub 2020 Nov 19.

Division of Dermatology, UCLA, Los Angeles, United States of America.

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http://dx.doi.org/10.1172/JCI141594DOI Listing
November 2020

β-Globin Lentiviral Vectors Have Reduced Titers due to Incomplete Vector RNA Genomes and Lowered Virion Production.

Stem Cell Reports 2020 Oct 30. Epub 2020 Oct 30.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Terasaki Life Sciences Building, 610 Charles E. Young Drive East, Los Angeles, CA 90095-1489, USA; Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, USA; Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, USA; The Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research, University of California, Los Angeles, USA; UCLA Jonsson Comprehensive Cancer Center, Los Angeles, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2020.10.007DOI Listing
October 2020

Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age.

JCI Insight 2020 Nov 12. Epub 2020 Nov 12.

Division of Cardiology, UCLA, Los Angeles, United States of America.

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http://dx.doi.org/10.1172/jci.insight.140628DOI Listing
November 2020

A rat epigenetic clock recapitulates phenotypic aging and co-localizes with heterochromatin.

Elife 2020 11 12;9. Epub 2020 Nov 12.

Translational Gerontology Branch, Biomedical Research Center, National Institute on Aging, National Institutes of Health, Baltimore, United States.

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http://dx.doi.org/10.7554/eLife.59201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661040PMC
November 2020

Cell-free DNA Methylation and Transcriptomic Signature Prediction of Pregnancies with Adverse Outcomes.

Epigenetics 2020 Oct 13:1-20. Epub 2020 Oct 13.

Departments of Pediatrics David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

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http://dx.doi.org/10.1080/15592294.2020.1816774DOI Listing
October 2020

Pro-inflammatory cytokine polymorphisms in ONECUT2 and HNF4A and primary colorectal carcinoma: a post genome-wide gene-lifestyle interaction study.

Am J Cancer Res 2020 1;10(9):2955-2976. Epub 2020 Sep 1.

Department of Epidemiology, Fielding School of Public Health, University of California Los Angeles, CA 90095, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539781PMC
September 2020

Genome-wide Association Analysis of Proinflammatory Cytokines and Gene-lifestyle Interaction for Invasive Breast Cancer Risk: The WHI dbGaP Study.

Cancer Prev Res (Phila) 2020 Sep 14. Epub 2020 Sep 14.

Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1158/1940-6207.CAPR-20-0256DOI Listing
September 2020

Integrative Analysis of Glucometabolic Traits, Adipose Tissue DNA Methylation, and Gene Expression Identifies Epigenetic Regulatory Mechanisms of Insulin Resistance and Obesity in African Americans.

Diabetes 2020 Dec 14;69(12):2779-2793. Epub 2020 Sep 14.

Department of Internal Medicine, Section of Endocrinology and Metabolism, Wake Forest School of Medicine, Winston-Salem, NC

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http://dx.doi.org/10.2337/db20-0117DOI Listing
December 2020

How prior pair-bonding experience affects future bonding behavior in monogamous prairie voles.

Horm Behav 2020 Sep 30;126:104847. Epub 2020 Sep 30.

Department of Psychology and Neuroscience, University of Colorado Boulder, 80309, USA; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, 80309, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yhbeh.2020.104847DOI Listing
September 2020

Targeted bisulfite sequencing for biomarker discovery.

Methods 2020 Aug 2. Epub 2020 Aug 2.

Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095, United States; UCLA-DOE Institute for Genomics and Proteomics, University of California Los Angeles, Los Angeles, CA 90095, United States; Institute for Quantitative and Computational Biosciences - The Collaboratory, University of California Los Angeles, Los Angeles, CA 90095, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2020.07.006DOI Listing
August 2020

Effects of sulforaphane on the oxidative response, apoptosis, and the transcriptional profile of human stomach mucosa cells in vitro.

Mutat Res 2020 Jun - Jul;854-855:503201. Epub 2020 May 31.

Department of Clinical Analysis, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, SP, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.mrgentox.2020.503201DOI Listing
October 2020

Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury.

Cell 2020 Aug 3;182(3):545-562.e23. Epub 2020 Jul 3.

Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA; UCLA Cardiovascular Theme, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA; Department of Molecular, Cell and Developmental Biology, College of Letters and Sciences, University of California, Los Angeles, CA 90095, USA; Eli & Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA 90095, USA; Molecular Biology Institute, University of California, Los Angeles, CA 90095, USA; California Nanosystems Institute, University of California, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.06.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7415659PMC
August 2020

The Epigenetic Pacemaker: modeling epigenetic states under an evolutionary framework.

Bioinformatics 2020 Nov;36(17):4662-4663

Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btaa585DOI Listing
November 2020

Creating New β-Globin-Expressing Lentiviral Vectors by High-Resolution Mapping of Locus Control Region Enhancer Sequences.

Mol Ther Methods Clin Dev 2020 Jun 18;17:999-1013. Epub 2020 Apr 18.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.omtm.2020.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7225380PMC
June 2020

ER Stress Regulates Immunosuppressive Function of Myeloid Derived Suppressor Cells in Leprosy that Can Be Overcome in the Presence of IFN-γ.

iScience 2020 May 12;23(5):101050. Epub 2020 Apr 12.

Division of Dermatology, David Geffen School of Medicine, Los Angeles, CA 90095, USA; Department of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.isci.2020.101050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190750PMC
May 2020

Molecular signatures for inflammation vary across cancer types and correlate significantly with tumor stage, sex and vital status of patients.

PLoS One 2020 24;15(4):e0221545. Epub 2020 Apr 24.

Department of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221545PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182171PMC
July 2020

Impacts of ciliary neurotrophic factor on the retinal transcriptome in a mouse model of photoreceptor degeneration.

Sci Rep 2020 04 20;10(1):6593. Epub 2020 Apr 20.

Department of Ophthalmology and Stein Eye Institute, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1038/s41598-020-63519-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7171121PMC
April 2020

Cellular, Molecular, and Immunological Characteristics of Langhans Multinucleated Giant Cells Programmed by IL-15.

J Invest Dermatol 2020 Sep 22;140(9):1824-1836.e7. Epub 2020 Feb 22.

Department of Medicine, Division of Dermatology, David Geffen School of Medicine at University of California (UCLA), Los Angeles, California, USA; Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine at University of California (UCLA), Los Angeles, California, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2020.01.026DOI Listing
September 2020

Telescope: an interactive tool for managing large-scale analysis from mobile devices.

Gigascience 2020 01;9(1)

Department of Clinical Pharmacy, School of Pharmacy, University of Southern California, 1985 Zonal Avenue, Los Angeles, CA 90089-9121, USA.

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http://dx.doi.org/10.1093/gigascience/giz163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977584PMC
January 2020

DNA Methylation Changes More Slowly Than Physiological States in Response to Weight Loss in Genetically Diverse Mouse Strains.

Front Endocrinol (Lausanne) 2019 20;10:882. Epub 2019 Dec 20.

Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA, United States.

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http://dx.doi.org/10.3389/fendo.2019.00882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933503PMC
December 2019

Genome-wide DNA Methylation Profiling of Blood from Monozygotic Twins Discordant for Myocardial Infarction.

In Vivo 2020 Jan-Feb;34(1):361-367

Department of Molecular, Cell and Developmental Biology, David Geffen School of Medicine, University of California, Los Angeles, CA, U.S.A.

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http://dx.doi.org/10.21873/invivo.11782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6984093PMC
June 2020

Transcriptome and DNA methylation changes modulated by sulforaphane induce cell cycle arrest, apoptosis, DNA damage, and suppression of proliferation in human liver cancer cells.

Food Chem Toxicol 2020 Feb 12;136:111047. Epub 2019 Dec 12.

Department of Clinical Analysis, Toxicology and Food Sciences, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Av. do Café - Vila Monte Alegre, Ribeirão Preto, SP, 14040-903, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2019.111047DOI Listing
February 2020

Activation of the HIF1α/PFKFB3 stress response pathway in beta cells in type 1 diabetes.

Diabetologia 2020 01 13;63(1):149-161. Epub 2019 Nov 13.

Larry L. Hillblom Islet Research Center, David Geffen School of Medicine at UCLA, University of California Los Angeles, 10833 Le Conte Avenue, 33-165 CHS, Los Angeles, CA, 90095-7073, USA.

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http://dx.doi.org/10.1007/s00125-019-05030-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945783PMC
January 2020

Identification of a systemic interferon-γ inducible antimicrobial gene signature in leprosy patients undergoing reversal reaction.

PLoS Negl Trop Dis 2019 10 10;13(10):e0007764. Epub 2019 Oct 10.

Division of Dermatology, Department of Medicine, David Geffen School of Medicine at University of California (UCLA), Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0007764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805014PMC
October 2019

The size of cell-free mitochondrial DNA in blood is inversely correlated with tumor burden in cancer patients.

Precis Clin Med 2019 Sep 1;2(3):131-139. Epub 2019 Oct 1.

Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1093/pcmedi/pbz014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770274PMC
September 2019

Interactions between core histone marks and DNA methyltransferases predict DNA methylation patterns observed in human cells and tissues.

Epigenetics 2020 03 17;15(3):272-282. Epub 2019 Sep 17.

Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1080/15592294.2019.1666649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7028327PMC
March 2020

ACTINN: automated identification of cell types in single cell RNA sequencing.

Bioinformatics 2020 01;36(2):533-538

Molecular Biology Institute, University of California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btz592DOI Listing
January 2020

The cell fate regulator NUPR1 is induced by Mycobacterium leprae via type I interferon in human leprosy.

PLoS Negl Trop Dis 2019 07 25;13(7):e0007589. Epub 2019 Jul 25.

Division of Dermatology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0007589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684084PMC
July 2019

RNA Modulates the Expression of Cell Cycle Genes in Human Fibroblasts.

Int J Mol Sci 2019 Jul 5;20(13). Epub 2019 Jul 5.

Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy.

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http://dx.doi.org/10.3390/ijms20133315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651528PMC
July 2019

H3K36 Methylation and the Chromodomain Protein Eaf3 Are Required for Proper Cotranscriptional Spliceosome Assembly.

Cell Rep 2019 06;27(13):3760-3769.e4

Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA; Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.05.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904931PMC
June 2019

IL-1β Induces the Rapid Secretion of the Antimicrobial Protein IL-26 from Th17 Cells.

J Immunol 2019 08 24;203(4):911-921. Epub 2019 Jun 24.

Division of Dermatology, Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA 90095;

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http://dx.doi.org/10.4049/jimmunol.1900318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6684376PMC
August 2019

Human epigenetic ageing is logarithmic with time across the entire lifespan.

Epigenetics 2019 09 6;14(9):912-926. Epub 2019 Jun 6.

b Department of Molecular, Cell and Developmental Biology, University of California , Los Angeles , CA , USA.

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http://dx.doi.org/10.1080/15592294.2019.1623634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691990PMC
September 2019

DNA methylation estimation using methylation-sensitive restriction enzyme bisulfite sequencing (MREBS).

PLoS One 2019 4;14(4):e0214368. Epub 2019 Apr 4.

Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214368PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448829PMC
December 2019

Endocardially Derived Macrophages Are Essential for Valvular Remodeling.

Dev Cell 2019 03 21;48(5):617-630.e3. Epub 2019 Feb 21.

Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA; Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, Los Angeles, CA 90095, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2019.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440481PMC
March 2019

Comparison of reprogramming factor targets reveals both species-specific and conserved mechanisms in early iPSC reprogramming.

BMC Genomics 2018 Dec 22;19(1):956. Epub 2018 Dec 22.

Department of Molecular, Cellular and Developmental Biology, Bioinformatics Interdepartmental Program, University of California Los Angeles, Los Angeles, CA, 90095, USA.

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https://bmcgenomics.biomedcentral.com/articles/10.1186/s1286
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http://dx.doi.org/10.1186/s12864-018-5326-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303873PMC
December 2018

Plasticity of antimicrobial and phagocytic programs in human macrophages.

Immunology 2019 02 11;156(2):164-173. Epub 2018 Nov 11.

Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

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http://doi.wiley.com/10.1111/imm.13013
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http://dx.doi.org/10.1111/imm.13013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328994PMC
February 2019

A multi-tissue full lifespan epigenetic clock for mice.

Aging (Albany NY) 2018 10;10(10):2832-2854

Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.18632/aging.101590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224226PMC
October 2018

A temporal transcriptome and methylome in human embryonic stem cell-derived cardiomyocytes identifies novel regulators of early cardiac development.

Epigenetics 2018 19;13(10-11):1013-1026. Epub 2018 Oct 19.

a Department of Molecular, Cell, and Developmental Biology , University of California , Los Angeles , CA , USA.

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http://dx.doi.org/10.1080/15592294.2018.1526029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342070PMC
March 2019

Directed strain evolution restructures metabolism for 1-butanol production in minimal media.

Metab Eng 2018 09 11;49:153-163. Epub 2018 Aug 11.

Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan. Electronic address:

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http://dx.doi.org/10.1016/j.ymben.2018.08.004DOI Listing
September 2018

Seed genome hypomethylated regions are enriched in transcription factor genes.

Proc Natl Acad Sci U S A 2018 08 13;115(35):E8315-E8322. Epub 2018 Aug 13.

Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, CA 90095;

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http://dx.doi.org/10.1073/pnas.1811017115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126732PMC
August 2018

GATA4 represses RANKL in osteoblasts via multiple long-range enhancers to regulate osteoclast differentiation.

Bone 2018 11 19;116:78-86. Epub 2018 Jul 19.

Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2018.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158087PMC
November 2018

CRACR2A-Mediated TCR Signaling Promotes Local Effector Th1 and Th17 Responses.

J Immunol 2018 08 9;201(4):1174-1185. Epub 2018 Jul 9.

Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095;

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http://dx.doi.org/10.4049/jimmunol.1800659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081249PMC
August 2018

An epigenetic pacemaker is detected via a fast conditional expectation maximization algorithm.

Epigenomics 2018 06;10(6):695-706

Deptartment of Molecular, Cell & Developmental Biology, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.2217/epi-2017-0130DOI Listing
June 2018

Synaptic N-methyladenosine (mA) epitranscriptome reveals functional partitioning of localized transcripts.

Nat Neurosci 2018 07 27;21(7):1004-1014. Epub 2018 Jun 27.

Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1038/s41593-018-0173-6DOI Listing
July 2018

Transposon-associated epigenetic silencing during Pleurotus ostreatus life cycle.

DNA Res 2018 Oct;25(5):451-464

Genetics and Microbiology Research Group, Department of Agrarian Production, Public University of Navarre, Pamplona, Navarre, Spain.

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http://dx.doi.org/10.1093/dnares/dsy016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191308PMC
October 2018

Vav3-induced cytoskeletal dynamics contribute to heterotypic properties of endothelial barriers.

J Cell Biol 2018 08 1;217(8):2813-2830. Epub 2018 Jun 1.

Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA

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http://dx.doi.org/10.1083/jcb.201706041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080943PMC
August 2018

The Memory of Environmental Chemical Exposure in C. elegans Is Dependent on the Jumonji Demethylases jmjd-2 and jmjd-3/utx-1.

Cell Rep 2018 05;23(8):2392-2404

Molecular Toxicology Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA 90095, USA; Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA; Institute for Society and Genetics, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.04.078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6003705PMC
May 2018

Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence.

Stem Cell Reports 2018 05;10(5):1453-1463

Department of Molecular Cell and Developmental Biology, UCLA, Los Angeles, CA 90095, USA; Eli and Edythe Broad Center for Regenerative Medicine, UCLA, Los Angeles, CA 90095, USA; Molecular Biology Institute, UCLA, Los Angeles, CA 90095, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995366PMC
May 2018

Similarity between soybean and seed methylomes and loss of non-CG methylation does not affect seed development.

Proc Natl Acad Sci U S A 2017 11 23;114(45):E9730-E9739. Epub 2017 Oct 23.

Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, CA 90095;

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http://dx.doi.org/10.1073/pnas.1716758114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5692608PMC
November 2017

SaVanT: a web-based tool for the sample-level visualization of molecular signatures in gene expression profiles.

BMC Genomics 2017 Oct 25;18(1):824. Epub 2017 Oct 25.

Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, CA, 90095, USA.

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http://dx.doi.org/10.1186/s12864-017-4167-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657101PMC
October 2017

Targeted mutagenesis in a human-parasitic nematode.

PLoS Pathog 2017 Oct 10;13(10):e1006675. Epub 2017 Oct 10.

Molecular Biology Institute, University of California, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1006675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650185PMC
October 2017

CGmapTools improves the precision of heterozygous SNV calls and supports allele-specific methylation detection and visualization in bisulfite-sequencing data.

Bioinformatics 2018 02;34(3):381-387

State Key Laboratory for Agrobiotechnology, Key Laboratory of Crop Heterosis and Utilization, Beijing Key Laboratory of Crop Genetic Improvement, China Agricultural University, Beijing 100193, China.

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http://dx.doi.org/10.1093/bioinformatics/btx595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454434PMC
February 2018

Divergence in Morris Water Maze-Based Cognitive Performance under Chronic Stress Is Associated with the Hippocampal Whole Transcriptomic Modification in Mice.

Front Mol Neurosci 2017 30;10:275. Epub 2017 Aug 30.

Applied Neuroscience, Warfighter Interface Division, 711th Human Performance Wing, Air Force Research LaboratoryWright-Patterson AFB, OH, United States.

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http://dx.doi.org/10.3389/fnmol.2017.00275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582454PMC
August 2017

High-Resolution Mapping of Chromatin Conformation in Cardiac Myocytes Reveals Structural Remodeling of the Epigenome in Heart Failure.

Circulation 2017 Oct 11;136(17):1613-1625. Epub 2017 Aug 11.

From Departments of Anesthesiology and Perioperative Medicine (M.R.-G., D.J.C., T.H.K., E.K., E.M., T.-T.S., E.S., S.R., Y.W., T.M.V.), Medicine (D.L., P.P., Y.W., T.M.V.), Physiology (P.P.,Y.W., T.M.V.), Molecular, Cellular and Developmental Biology (M.P.), UCLA, Los Angeles, CA; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City (E.B.); Ludwig Institute for Cancer Research, Department of Cellular and Molecular Medicine, Institute of Genomic Medicine, and Moores Cancer Center, UCSD, San Diego, CA (A.D.S., B.R.); and Department of Cell Biology and Genetics, Erasmus MC, Rotterdam, The Netherlands (N.J.G.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.029430DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5648689PMC
October 2017

Addressing the Digital Divide in Contemporary Biology: Lessons from Teaching UNIX.

Trends Biotechnol 2017 10 15;35(10):901-903. Epub 2017 Jul 15.

Department of Computer Science, University of California Los Angeles, 580 Portola Plaza, Los Angeles, CA 90095, USA; Department of Human Genetics, University of California Los Angeles, 695 Charles E. Young Drive South, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.tibtech.2017.06.007DOI Listing
October 2017

Prenatal Growth Patterns and Birthweight Are Associated With Differential DNA Methylation and Gene Expression of Cardiometabolic Risk Genes in Human Placentas: A Discovery-Based Approach.

Reprod Sci 2018 04 11;25(4):523-539. Epub 2017 Jul 11.

2 Division of Neonatology and Developmental Biology, Department of Pediatrics, Neonatal Research Center of the UCLA Children's Discovery and Innovation Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.

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http://journals.sagepub.com/doi/10.1177/1933719117716779
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http://dx.doi.org/10.1177/1933719117716779DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348426PMC
April 2018

Omega-3 fatty acids increase the unfolded protein response and improve amyloid-β phagocytosis by macrophages of patients with mild cognitive impairment.

FASEB J 2017 10 20;31(10):4359-4369. Epub 2017 Jun 20.

Department of Cell, Molecular, and Developmental Biology, UCLA Life Sciences, University of California, Los Angeles, Los Angeles, California, USA;

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http://dx.doi.org/10.1096/fj.201700290RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602894PMC
October 2017

Chromosome-level genome assembly and transcriptome of the green alga illuminates astaxanthin production.

Proc Natl Acad Sci U S A 2017 05 8;114(21):E4296-E4305. Epub 2017 May 8.

Howard Hughes Medical Institute, Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720-3102;

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http://dx.doi.org/10.1073/pnas.1619928114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448231PMC
May 2017

Modulation of innate immunity of patients with Alzheimer's disease by omega-3 fatty acids.

FASEB J 2017 08 18;31(8):3229-3239. Epub 2017 Apr 18.

Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, Los Angeles, California, USA.

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http://dx.doi.org/10.1096/fj.201700065RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503712PMC
August 2017

Altered methylation of specific DNA loci in the liver of -null mice results in repression of and and is associated with development of preneoplastic foci.

FASEB J 2017 05 8;31(5):2090-2103. Epub 2017 Feb 8.

Department of Nutrition, Nutrition Research Institute, University of North Carolina at Chapel Hill, Kannapolis, North Carolina, USA;

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http://dx.doi.org/10.1096/fj.201601169RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388550PMC
May 2017

Abf1 and other general regulatory factors control ribosome biogenesis gene expression in budding yeast.

Nucleic Acids Res 2017 05;45(8):4493-4506

Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 23/A, 43124 Parma, Italy.

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http://dx.doi.org/10.1093/nar/gkx058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5416754PMC
May 2017