Mathieu J M Bertrand

Mathieu J M Bertrand

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Mathieu J M Bertrand

Mathieu J M Bertrand

Publications by authors named "Mathieu J M Bertrand"

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Monitoring RIPK1 Phosphorylation in the TNFR1 Signaling Complex.

Methods Mol Biol 2018 ;1857:171-179

VIB Center for Inflammation Research, Zwijnaarde-Ghent, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-8754-2_17DOI Listing
May 2019

The E3 ubiquitin ligases HOIP and cIAP1 are recruited to the TNFR2 signaling complex and mediate TNFR2-induced canonical NF-κB signaling.

Biochem Pharmacol 2018 07 31;153:292-298. Epub 2018 Jan 31.

Center for Inflammation Research, VIB, Unit of Molecular Signal Transduction in Inflammation, Technologiepark 927, Zwijnaarde, Ghent 9052, Belgium; Department of Biomedical Molecular Biology, Ghent University, Technologiepark 927, Zwijnaarde, Ghent 9052, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2018.01.039DOI Listing
July 2018

N-glycosylation of mouse TRAIL-R restrains TRAIL-induced apoptosis.

Cell Death Dis 2018 05 1;9(5):494. Epub 2018 May 1.

VIB Center for Inflammation Research, Technologiepark 927, Zwijnaarde-Ghent, 9052, Belgium.

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http://dx.doi.org/10.1038/s41419-018-0544-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931557PMC
May 2018

Correction: Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells.

Oncotarget 2018 04 27;9(32):22871. Epub 2018 Apr 27.

Department of Structural Biology Research Center (SBRC), Research Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Flanders Institute for Biotechnology (VIB), Brussels, Belgium.

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http://dx.doi.org/10.18632/oncotarget.25336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978272PMC
April 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

MK2 phosphorylation of RIPK1 regulates TNF-mediated cell death.

Nat Cell Biol 2017 Oct 18;19(10):1237-1247. Epub 2017 Sep 18.

Inflammation Research Center, VIB, Technologiepark 927, Zwijnaarde-Ghent 9052, Belgium.

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http://dx.doi.org/10.1038/ncb3608DOI Listing
October 2017

RIPK1 protects hepatocytes from death in Fas-induced hepatitis.

Sci Rep 2017 08 23;7(1):9205. Epub 2017 Aug 23.

Institut National de la Santé et de la Recherche Médicale (Inserm), U.1085, Institut de Recherche en Santé, Environnement et Travail (IRSET), F-35043, Rennes, France.

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http://www.nature.com/articles/s41598-017-09789-8
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http://dx.doi.org/10.1038/s41598-017-09789-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569041PMC
August 2017

Experimental African trypanosome infection suppresses the development of multiple myeloma in mice by inducing intrinsic apoptosis of malignant plasma cells.

Oncotarget 2017 Aug 24;8(32):52016-52025. Epub 2017 May 24.

Department of Structural Biology Research Center (SBRC), Research Unit of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Flanders Institute for Biotechnology (VIB), Brussels, Belgium.

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http://dx.doi.org/10.18632/oncotarget.18152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581009PMC
August 2017

RIPK1 protects hepatocytes from Kupffer cells-mediated TNF-induced apoptosis in mouse models of PAMP-induced hepatitis.

J Hepatol 2017 06 11;66(6):1205-1213. Epub 2017 Jan 11.

Institut National de la Santé et de la Recherche Médicale (Inserm), U.1085, Institut de Recherche Santé Environnement et Travail (IRSET), F-35043 Rennes, France; Université de Rennes 1, F-35043 Rennes, France; Structure Fédérative BioSit UMS3480 CNRS-US18 Inserm, F-35043 Rennes, France.

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https://linkinghub.elsevier.com/retrieve/pii/S01688278173000
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http://dx.doi.org/10.1016/j.jhep.2017.01.005DOI Listing
June 2017

Regulation of RIPK1's cell death function by phosphorylation.

Cell Cycle 2016 ;15(1):5-6

a Inflammation Research Center, VIB ; Zwijnaarde-Ghent , Belgium.

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http://dx.doi.org/10.1080/15384101.2015.1112688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4825752PMC
October 2016

An evolutionary perspective on the necroptotic pathway.

Trends Cell Biol 2016 10 28;26(10):721-732. Epub 2016 Jun 28.

VIB Inflammation Research Center, Technologiepark 927, Zwijnaarde-Ghent, 9052, Belgium; Department of Biomedical Molecular Biology, Ghent University, Technologiepark 927, Zwijnaarde-Ghent, 9052, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2016.06.004DOI Listing
October 2016

A real-time fluorometric method for the simultaneous detection of cell death type and rate.

Nat Protoc 2016 08 14;11(8):1444-54. Epub 2016 Jul 14.

Molecular Signaling and Cell Death Unit, VIB Inflammation Research Center, Ghent, Belgium.

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http://dx.doi.org/10.1038/nprot.2016.085DOI Listing
August 2016

More to Life than NF-κB in TNFR1 Signaling.

Trends Immunol 2016 08 13;37(8):535-545. Epub 2016 Jul 13.

Inflammation Research Center, VIB, Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, Belgium. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5076853PMC
http://dx.doi.org/10.1016/j.it.2016.06.002DOI Listing
August 2016

Poly-ubiquitination in TNFR1-mediated necroptosis.

Cell Mol Life Sci 2016 06 11;73(11-12):2165-76. Epub 2016 Apr 11.

Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, London, UK.

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http://link.springer.com/content/pdf/10.1007%2Fs00018-016-21
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http://link.springer.com/10.1007/s00018-016-2191-4
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http://dx.doi.org/10.1007/s00018-016-2191-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887548PMC
June 2016

Polyhydramnios, Transient Antenatal Bartter's Syndrome, and MAGED2 Mutations.

N Engl J Med 2016 May 27;374(19):1853-63. Epub 2016 Apr 27.

From INSERM, Centre de Recherche des Cordeliers, Unité 1138, Centre National de la Recherche Scientifique, ERL8228 Université Pierre et Marie Curie and Université Paris-Descartes, Paris (K.L., E.S., S.D.); Institute of Human Genetics (B.B.B., A.W., B.R., J.A., G.Y.), Department of Pathology (H.G.), Cologne Center for Genomics and Center for Molecular Medicine (H.T., J.A., P.N.), Department II of Internal Medicine and Center for Molecular Medicine Cologne (M.P.B., T.B., M.M.R.), and Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases and Systems Biology of Aging Cologne (T.B., M.M.R.) - all at the University of Cologne, Cologne, the Department of Cellular and Integrative Physiology, University Medical Center Hamburg, Hamburg (H.V.), University Children's Hospital, Philipps University Marburg (H.W.S.), and Kuratorium für Heimdialyse, Pediatric Kidney Center (G.K.), Marburg, the Institute of Human Genetics, University Health Services Göttingen, Göttingen (G.Y.), and the Department of General Pediatrics, University Hospital Münster, Münster (K.P.S., M. Konrad) - all in Germany; the Division of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center (S.-S.Y., S.-H.L.), and Institute of BioMedical Sciences, Academia Sinica (S.-S.Y.) - both in Taipei, Taiwan; the Department of Biomedical Molecular Biology, Inflammation Research Center, VIB/Ghent University, Ghent (D.P., M.J.M.B.), Unité de Recherche en Physiologie Moléculaire, University of Namur, Namur (C.D., O.B.), and the Division of Nephrology, University Children's Hospital Leuven (E.L.) - all in Belgium; the Divisions of Neonatology (K.B.) and Nephrology (M. Kömhoff), Beatrix Children's Hospital, and the Departments of Obstetrics and Gynecology (L.K.D., S.A.S.), Pathology and Medical Biology (A.T.), and Genetics (T.J.K.) - all at University Medical Center Groningen, Groningen, the Netherlands; and University Children's Hospital Graz

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http://dx.doi.org/10.1056/NEJMoa1507629DOI Listing
May 2016

Vaccination with Necroptotic Cancer Cells Induces Efficient Anti-tumor Immunity.

Cell Rep 2016 Apr 31;15(2):274-87. Epub 2016 Mar 31.

Molecular Signaling and Cell Death Unit, Inflammation Research Center, VIB, 9052 Ghent, Belgium; Department of Biomedical Molecular Biology, Cancer Research Institute Ghent (CRIG), Ghent University, 9052 Ghent, Belgium.

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http://dx.doi.org/10.1016/j.celrep.2016.03.037DOI Listing
April 2016

NF-κB-Independent Role of IKKα/IKKβ in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling.

Mol Cell 2015 Oct 3;60(1):63-76. Epub 2015 Sep 3.

Inflammation Research Center, VIB, Technologiepark 927, Zwijnaarde-Ghent 9052, Belgium; Department of Biomedical Molecular Biology, Ghent University, Technologiepark 927, Zwijnaarde-Ghent 9052, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2015.07.032DOI Listing
October 2015

cIAP2 supports viability of mice lacking cIAP1 and XIAP.

EMBO J 2015 Oct;34(19):2393-5

Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.15252/embj.201592060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601659PMC
October 2015

IAPs, regulators of innate immunity and inflammation.

Semin Cell Dev Biol 2015 Mar 6;39:106-14. Epub 2014 Apr 6.

Inflammation Research Center, VIB, Technologiepark 927, Zwijnaarde-Ghent 9052, Belgium; Department of Biomedical Molecular Biology, Ghent University, Technologiepark 927, Zwijnaarde-Ghent 9052, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2014.03.035DOI Listing
March 2015

RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.

Nature 2014 Sep;513(7516):95-9

1] VIB Inflammation Research Center, Technologiepark 927, B-9052 Ghent, Belgium [2] Department of Biomedical Molecular Biology, Ghent University, Technologiepark 927, B-9052 Ghent, Belgium [3] Methusalem program, Ghent University, Technologiepark 927, B-9052 Ghent, Belgium.

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http://dx.doi.org/10.1038/nature13706DOI Listing
September 2014

MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates.

Cell Rep 2014 May 9;7(4):971-81. Epub 2014 May 9.

VIB Inflammation Research Center, Technologiepark 927, 9052 Zwijnaarde-Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, Technologiepark 927, 9052 Zwijnaarde-Ghent, Belgium; Methusalem Program, Ghent University, Technologiepark 927, 9052 Zwijnaarde-Ghent, Belgium. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(14)00328-3.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471400328
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http://dx.doi.org/10.1016/j.celrep.2014.04.026DOI Listing
May 2014

Caspase-3 and RasGAP: a stress-sensing survival/demise switch.

Trends Cell Biol 2014 Feb 2;24(2):83-9. Epub 2013 Sep 2.

Department of Physiology, University of Lausanne, Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2013.08.002DOI Listing
February 2014

The role of the IAP E3 ubiquitin ligases in regulating pattern-recognition receptor signalling.

Nat Rev Immunol 2012 Dec 5;12(12):833-44. Epub 2012 Nov 5.

Department for Molecular Biomedical Research, VIB, B-9052 Ghent, Belgium.

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http://www.nature.com/articles/nri3325
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http://dx.doi.org/10.1038/nri3325DOI Listing
December 2012

Loss of Maged1 results in obesity, deficits of social interactions, impaired sexual behavior and severe alteration of mature oxytocin production in the hypothalamus.

Hum Mol Genet 2012 Nov 2;21(21):4703-17. Epub 2012 Aug 2.

Unité de Recherche en Physiologie Moléculaire, Namur Research Institute for Life Sciences, FUNDP School of Medicine, University of Namur, 61 rue de Bruxelles, Namur B-5000, Belgium.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/dds310DOI Listing
November 2012

The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress.

Biol Cell 2012 May 29;104(5):259-70. Epub 2012 Feb 29.

Apoptosis Research Centre, National University of Ireland Galway, Galway, Ireland.

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http://doi.wiley.com/10.1111/boc.201100055
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http://dx.doi.org/10.1111/boc.201100055DOI Listing
May 2012

NOD-like receptors and the innate immune system: coping with danger, damage and death.

Cytokine Growth Factor Rev 2011 Oct-Dec;22(5-6):257-76. Epub 2011 Oct 12.

Department for Molecular Biomedical Research, Unit for Molecular Signaling and Cell Death, Technologiepark 927, B-9052 Ghent, Belgium.

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http://dx.doi.org/10.1016/j.cytogfr.2011.09.003DOI Listing
April 2012

The Ripoptosome: death decision in the cytosol.

Mol Cell 2011 Aug;43(3):323-5

Molecular Signaling and Cell Death Unit, Department for Molecular Biomedical Research, VIB, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.molcel.2011.07.007DOI Listing
August 2011

Maged1, a new regulator of skeletal myogenic differentiation and muscle regeneration.

BMC Cell Biol 2010 Jul 20;11:57. Epub 2010 Jul 20.

Unité de Recherche en Physiologie Moléculaire, Namur Research Institute for Life Sciences, FUNDP school of Medicine, University of Namur, 21 rue de Bruxelles, Namur B-5000, Belgium.

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http://dx.doi.org/10.1186/1471-2121-11-57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2912822PMC
July 2010

Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.

Immunity 2009 Jun 21;30(6):789-801. Epub 2009 May 21.

Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.immuni.2009.04.011DOI Listing
June 2009

Apoptotic sensitivity of murine IAP-deficient cells.

Biochem J 2008 Oct;415(1):21-5

Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1042/BJ20081188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676106PMC
October 2008