Mathias W Pletz

Mathias W Pletz

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Mathias W Pletz

Mathias W Pletz

Publications by authors named "Mathias W Pletz"

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100Publications

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Polyester-based particles to overcome the obstacles of mucus and biofilms in the lung for tobramycin application under static and dynamic fluidic conditions.

Eur J Pharm Biopharm 2018 Oct 29;131:120-129. Epub 2018 Jul 29.

Pharmaceutical Technology and Biopharmacy, Institute for Pharmacy, Friedrich Schiller University Jena, Jena, Germany; Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Jena, Germany.

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October 2018

Development of a clinical decision rule for diagnosing sinus infections - to reduce unnecessary antibiotic prescribing.

Expert Rev Clin Pharmacol 2018 Sep 14. Epub 2018 Sep 14.

b Institute of Infectious Diseases and Infection Control Jena University Hospital.

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September 2018

Antibiotic use on paediatric inpatients in a teaching hospital in the Gambia, a retrospective study.

Antimicrob Resist Infect Control 2018 16;7:82. Epub 2018 Jul 16.

2Institute for Medical Epidemiology, Biometry, and Informatics (IMEBI), Medical Faculty of the Martin-Luther University Halle-Wittenberg, 06112 Halle (Saale), Germany.

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July 2018

Microorganisms @ materials surfaces in aircraft: Potential risks for public health? - A systematic review.

Travel Med Infect Dis 2018 Jul 27. Epub 2018 Jul 27.

Chair of Materials Science (CMS), Otto Schott Institute of Materials Research (OSIM), Friedrich Schiller University Jena, Löbdergraben 32, 07743, Jena, Germany; Jena School for Microbial Communication (JSMC), Friedrich Schiller University Jena, Neugasse 23, 07743, Jena, Germany. Electronic address:

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July 2018

In vitro synergism and anti-biofilm activity of ampicillin, gentamicin, ceftaroline and ceftriaxone against Enterococcus faecalis.

J Antimicrob Chemother 2018 Jun;73(6):1553-1561

Institute of Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany.

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June 2018

[Urosepsis].

Med Klin Intensivmed Notfmed 2018 03;113(2):143-156

Klinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Justus-Liebig-Universität Gießen, Rudolf-Buchheim-Str. 7, 35392, Gießen, Deutschland.

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March 2018

Naso- and oropharyngeal bacterial carriage in nursing home residents: Impact of multimorbidity and functional impairment.

PLoS One 2018 5;13(1):e0190716. Epub 2018 Jan 5.

Institute of Medical Statistics, Computer Sciences and Documentation, Jena University Hospital, Jena, Thuringia, Germany.

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February 2018

[Urosepsis].

Urologe A 2018 Jan;57(1):79-92

Klinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Justus-Liebig-Universität Gießen, Rudolf-Buchheim-Str. 7, 35392, Gießen, Deutschland.

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January 2018

Does medical education predispose to risk behaviour during travel?

Travel Med Infect Dis 2017 Jan - Feb;15:74-75. Epub 2016 Oct 26.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07740, Jena, Thuringia, Germany. Electronic address:

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September 2017

Ultrasensitive Detection of Antiseptic Antibiotics in Aqueous Media and Human Urine Using Deep UV Resonance Raman Spectroscopy.

Anal Chem 2017 Sep 25;89(18):9997-10003. Epub 2017 Aug 25.

Leibniz Institute of Photonic Technology , Jena 07745, Germany.

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September 2017

Deficits in knowledge, attitude, and practice towards blood culture sampling: results of a nationwide mixed-methods study among inpatient care physicians in Germany.

Infection 2017 Aug 15;45(4):433-441. Epub 2017 Feb 15.

ESME - Epidemiological and Statistical Methods Research Group, Department of Epidemiology, Helmholtz Centre for Infection Research, Inhoffenstr. 7, 38124, Brunswick, Germany.

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August 2017

A Novel Computerized Cell Count Algorithm for Biofilm Analysis.

PLoS One 2016 5;11(5):e0154937. Epub 2016 May 5.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany.

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July 2017

Who benefits from antimicrobial combination therapy?

Lancet Infect Dis 2017 07 22;17(7):677-678. Epub 2017 Apr 22.

Center for Infectious Diseases and Infection Control, Jena University Hospital, 07747 Jena, Germany; Department of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Vienna, Austria.

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July 2017

Fluoroquinolone resistance in Streptococcus pneumoniae isolates in Germany from 2004-2005 to 2014-2015.

Int J Med Microbiol 2017 Jun 19;307(4-5):216-222. Epub 2017 Apr 19.

Institute of Medical Microbiology, National Reference Center for Streptococci, University Hospital (RWTH), Aachen, Germany.

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June 2017

Health problems and behavioural risks in travellers to the tropics - A commentary.

Travel Med Infect Dis 2016 May-Jun;14(3):279-80. Epub 2016 Apr 14.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07740 Jena, Thuringia, Germany. Electronic address:

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April 2017

Effects of colistin on biofilm matrices of Escherichia coli and Staphylococcus aureus.

Int J Antimicrob Agents 2017 Apr 4;49(4):472-479. Epub 2017 Mar 4.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07747 Jena, Germany; InfectoGnostics Research Campus, Philosophenweg 7, 07743 Jena, Germany.

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April 2017

Time to follow up when comparing studies of pneumococcal vaccines.

Lancet Infect Dis 2017 03 24;17(3):244-246. Epub 2017 Jan 24.

Department of Pulmonary Medicine, German Center of Lung Research (DZL), Hannover Medical School, Hannover, Germany; CAPNETZ Foundation, Hannover, Germany.

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March 2017

Knowledge, attitude and practice of Gambian health practitioners towards antibiotic prescribing and microbiological testing: a cross-sectional survey.

Trans R Soc Trop Med Hyg 2017 03;111(3):117-124

ESME - Epidemiological and Statistical Methods Research Group, Department of Epidemiology, Helmholtz Centre for Infection Research, 38124 Braunschweig, Germany.

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March 2017

In silico serine β-lactamases analysis reveals a huge potential resistome in environmental and pathogenic species.

Sci Rep 2017 02 24;7:43232. Epub 2017 Feb 24.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany.

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February 2017

TiO-containing and ZnO-containing borosilicate glass-a novel thin glass with exceptional antibiofilm performances to prevent microfouling.

J Mater Sci Mater Med 2016 Dec 17;27(12):175. Epub 2016 Oct 17.

Center for Sepsis Control and Care, Jena University Hospital, Jena, 07747, Germany.

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December 2016

Were Antibody Titers the Right Parameter When Immunologically Comparing Pneumococcal Vaccines?

Am J Respir Crit Care Med 2016 12;194(12):1447-1448

3 Department for Respiratory Medicine Hannover Medical School Hannover, Germany.

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December 2016

Pre-operative stroke and neurological disability do not independently affect short- and long-term mortality in infective endocarditis patients.

Clin Res Cardiol 2016 Oct 27;105(10):847-57. Epub 2016 Apr 27.

Department of Cardiothoracic Surgery, Jena University Hospital-Friedrich Schiller University of Jena, Erlanger Allee 101, 07747, Jena, Germany.

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October 2016

Characteristics and management of patients with influenza in a German hospital during the 2014/2015 influenza season.

Infection 2016 Oct 5;44(5):667-72. Epub 2016 Jul 5.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07747, Jena, Germany.

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October 2016

Vaccines against major ICU pathogens: where do we stand?

Curr Opin Crit Care 2016 10;22(5):470-6

aCenter for Infectious Diseases and Infection Control, Jena University Hospital, JenabDivision of Microbiology, Paul-Ehrlich-Institut, Langen, Germany.

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October 2016

Fiber enhanced Raman spectroscopic analysis as a novel method for diagnosis and monitoring of diseases related to hyperbilirubinemia and hyperbiliverdinemia.

Analyst 2016 Oct;141(21):6104-6115

Leibniz Institute of Photonic Technology, Jena, Germany and Friedrich Schiller University, Institute for Physical Chemistry, Jena, Germany and Friedrich Schiller University, Abbe Centre of Photonics, Jena, Germany.

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October 2016

A blue fluorescent labeling technique utilizing micro- and nanoparticles for tracking in LIVE/DEAD® stained pathogenic biofilms of Staphylococcus aureus and Burkholderia cepacia.

Int J Nanomedicine 2016 5;11:575-83. Epub 2016 Feb 5.

Center for Infectious Diseases and Infection's Control, Jena University Hospital, Jena, Germany; Center for Sepsis Control and Care, Jena University Hospital, Jena, Germany.

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September 2016

Lab-on-a-Chip-Surface Enhanced Raman Scattering Combined with the Standard Addition Method: Toward the Quantification of Nitroxoline in Spiked Human Urine Samples.

Anal Chem 2016 09 8;88(18):9173-80. Epub 2016 Sep 8.

Friedrich Schiller University Jena , Institute of Physical Chemistry and Abbe Center of Photonics, Helmholtzweg 4, 07745 Jena, Germany.

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September 2016

Bactericidal Effect of a Photoresponsive Carbon Monoxide-Releasing Nonwoven against Staphylococcus aureus Biofilms.

Antimicrob Agents Chemother 2016 07 20;60(7):4037-46. Epub 2016 Jun 20.

Friedrich Schiller University Jena, Institute for Inorganic and Analytical Chemistry, Jena, Germany

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July 2016

Can radiological characteristics of preoperative cerebral lesions predict postoperative intracranial haemorrhage in endocarditis patients?

Eur J Cardiothorac Surg 2016 May 16;49(5):e119-26. Epub 2016 Feb 16.

Department of Cardiothoracic Surgery, Jena University Hospital - Friedrich Schiller University of Jena, Jena, Germany

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May 2016

Community-acquired Haemophilus influenzae pneumonia--New insights from the CAPNETZ study.

J Infect 2016 May 3;72(5):554-63. Epub 2016 Mar 3.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07747 Jena, Germany; CAPNETZ STIFTUNG, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany.

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May 2016

Development of a rapid diagnostic assay based on magnetic bead purification of OXA-β-lactamase mRNA.

Future Microbiol 2016 05 10;11:617-29. Epub 2016 May 10.

Center for Infectious Diseases & Infection Control, Jena University Hospital, Jena, Germany.

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May 2016

Three Dimensional Checkerboard Synergy Analysis of Colistin, Meropenem, Tigecycline against Multidrug-Resistant Clinical Klebsiella pneumonia Isolates.

PLoS One 2015 11;10(6):e0126479. Epub 2015 Jun 11.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, D-07747, Jena, Germany.

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April 2016

Bacterial Density, Serotype Distribution and Antibiotic Resistance of Pneumococcal Strains from the Nasopharynx of Peruvian Children Before and After Pneumococcal Conjugate Vaccine 7.

Pediatr Infect Dis J 2016 Apr;35(4):432-9

From the *Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia; †Department of Health Policy, School of Medicine, Vanderbilt University, Nashville, Tennessee; ‡Center for Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany; §Department of Environment and Health, School of Public Health, Bielefeld University, Bielefeld, Germany, ¶Vanderbilt Vaccine Research Program, Division of Infectious Diseases, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee; and ‖Instituto de Investigación Nutricional, Lima, Perú.

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April 2016

Impact of pneumococcal vaccination in children on serotype distribution in adult community-acquired pneumonia using the serotype-specific multiplex urinary antigen detection assay.

Vaccine 2016 Apr 24;34(20):2342-8. Epub 2016 Mar 24.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07747 Jena, Germany; Department of Medicine I, Division of Infectious Diseases and Tropical Medicine, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, Austria. Electronic address:

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April 2016

Advances in the prevention, management, and treatment of community-acquired pneumonia.

F1000Res 2016 8;5. Epub 2016 Mar 8.

Department of Pulmonary Medicine, Inselspital, University Hospital, Bern, Switzerland.

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March 2016

Development of visceral leishmaniasis in an HIV(+) patient upon immune reconstitution following the initiation of antiretroviral therapy.

Infection 2016 Feb 30;44(1):115-9. Epub 2015 Jun 30.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07740, Jena, Thuringia, Germany.

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February 2016

[Not Available].

Anasthesiol Intensivmed Notfallmed Schmerzther 2016 Feb 7;51(2):126-33; quiz 134. Epub 2016 Mar 7.

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February 2016

Infectious disease consultation for Staphylococcus aureus bacteremia - A systematic review and meta-analysis.

J Infect 2016 Jan 9;72(1):19-28. Epub 2015 Oct 9.

Paul Martini Sepsis Research Group, Department of Anaesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany; Center for Clinical Studies, Jena University Hospital, Jena, Germany; Integrated Research and Treatment Center, Center for Sepsis Control and Care (CSCC), Jena University Hospital, Jena, Germany. Electronic address:

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January 2016

Ventriculitis due to infection with Rhizopus arrhizus.

Med Mycol Case Rep 2015 Dec 15;10:18-20. Epub 2015 Dec 15.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07747 Jena, Germany.

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December 2015

Pneumococcal conjugate vaccine for adults: "It's tough to make predictions, ...".

Eur Respir J 2015 Nov;46(5):1265-8

Dept of Respiratory Medicine, Hannover Medical School, Hannover, Germany.

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November 2015

[Pneumococcal Vaccination for Adults - starting before 60? Pro].

Authors:
Mathias W Pletz

Dtsch Med Wochenschr 2015 Nov 3;140(23):1775. Epub 2015 Nov 3.

Zentrum für Infektionsmedizin und Krankenhaushygiene, Universitätsklinikum Jena.

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November 2015

Mutagenesis of the CTX-M-type ESBL-is MIC-guided treatment according to the new EUCAST recommendations a safe approach?

J Antimicrob Chemother 2015 Sep 12;70(9):2528-35. Epub 2015 Jun 12.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, D-07747 Jena, Germany

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September 2015

Aspects of pulmonary drug delivery strategies for infections in cystic fibrosis--where do we stand?

Expert Opin Drug Deliv 2015 Aug 2;12(8):1351-74. Epub 2015 Feb 2.

Jena University Hospital, Center for Infectious Diseases and Infection Control , Erlanger Allee 101, 07740 Jena , Germany +49 3641 9324227 ;

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August 2015

Quantifying the Hawthorne Effect in Hand Hygiene Compliance Through Comparing Direct Observation With Automated Hand Hygiene Monitoring.

Infect Control Hosp Epidemiol 2015 Aug 23;36(8):957-62. Epub 2015 Apr 23.

1Center for Infectious Diseases and Infection Control,Jena University Hospital,Jena,Germany.

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August 2015

Detection of pneumonia associated pathogens using a prototype multiplexed pneumonia test in hospitalized patients with severe pneumonia.

PLoS One 2014 14;9(11):e110566. Epub 2014 Nov 14.

University Hospital Jena, Institute of Medical Microbiology, Jena, Germany; University Hospital Jena, Center for Infectious Diseases and Infection Control, and Center for Sepsis Care and Control, Jena, Germany.

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July 2015

[Infectious disease medicine: change is not always progress].

Authors:
Mathias W Pletz

Dtsch Med Wochenschr 2015 Jun 26;140(13):974. Epub 2015 Jun 26.

Zentrum für Infektionsmedizin und Krankenhaushygiene, Universitätsklinikum Jena.

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June 2015

[Current strategies against multi-drug resistant organisms].

Dtsch Med Wochenschr 2015 Jun 26;140(13):975-81. Epub 2015 Jun 26.

Klinische Mikrobiologie und Krankenhaushygiene, Klinikum der Universität München.

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June 2015

[Staphylococcus aureus bacteremia - a distinct entity].

Dtsch Med Wochenschr 2015 Jun 26;140(13):982-9. Epub 2015 Jun 26.

Zentrum für Infektionsmedizin und Krankenhaushygiene, Universitätsklinikum Jena.

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June 2015

Direct RNA-based detection of CTX-M β-lactamases in human blood samples.

Int J Med Microbiol 2015 May 20;305(3):370-7. Epub 2015 Feb 20.

Center for Infectious Diseases and Infection's Control, Jena University Hospital, Erlanger Allee 101, D-07747 Jena, Germany.

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May 2015

[Unclear dermatological finding in a 35-year-old patient].

Dtsch Med Wochenschr 2015 Apr 31;140(7):513. Epub 2015 Mar 31.

Zentrum für Infektionsmedizin und Krankenhaushygiene, Universitätsklinikum Jena.

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April 2015

Increased Severity and Mortality of CAP in COPD: Results from the German Competence Network, CAPNETZ.

Chronic Obstr Pulm Dis 2015 Mar 26;2(2):131-140. Epub 2015 Mar 26.

Department of Respiratory Medicine, Maastricht University Medical Centre (MUMC+), Maastricht, the Netherlands.

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March 2015

Colonization with extended-spectrum beta-lactamase-producing and carbapenemase-producing Enterobacteriaceae in international travelers returning to Germany.

Int J Med Microbiol 2015 Jan 9;305(1):148-56. Epub 2014 Dec 9.

Institute for Medical Microbiology and Epidemiology of Infectious Diseases, Leipzig University Hospital, Liebigstr. 21, D-04103 Leipzig, Germany.

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January 2015

Non-invasive assessment of upper and lower airway infection and inflammation in CF patients.

Pediatr Pulmonol 2014 Nov 25;49(11):1065-75. Epub 2014 Jan 25.

Department of Paediatrics, Cystic Fibrosis Centre, Jena University Hospital, Jena, Germany.

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November 2014

The bigger picture: the history of antibiotics and antimicrobial resistance displayed by scientometric data.

Int J Antimicrob Agents 2014 Nov 25;44(5):424-30. Epub 2014 Aug 25.

Center for Infectious Diseases and Infection Control, Jena University Hospital, 07740 Jena, Germany.

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November 2014

Direct RNA-based detection and differentiation of CTX-M-type extended-spectrum β-lactamases (ESBL).

PLoS One 2013 5;8(11):e80079. Epub 2013 Nov 5.

Center for Infectious Diseases and Infection's Control, Jena University Hospital, Jena, Germany.

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June 2014

Vitamin D deficiency in community-acquired pneumonia: low levels of 1,25(OH)2 D are associated with disease severity.

Respir Res 2014 Apr 27;15:53. Epub 2014 Apr 27.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, 07740 Jena, Germany.

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April 2014

Bronchiectasis-associated hospitalizations in Germany, 2005-2011: a population-based study of disease burden and trends.

PLoS One 2013 1;8(8):e71109. Epub 2013 Aug 1.

Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.

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March 2014

HIV post exposure prophylaxis induced bicytopenia: a case report.

AIDS Res Ther 2014 Feb 7;11(1):11. Epub 2014 Feb 7.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Erlanger Allee 101, Jena, Thuringia 07740, Germany.

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February 2014

Clinical measures for increased creatinine clearances and suboptimal antibiotic dosing.

Intensive Care Med 2013 Jul 20;39(7):1322-4. Epub 2013 Apr 20.

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July 2013

Antihypertensives suppress the emergence of fluoroquinolone-resistant mutants in pneumococci: an in vitro study.

Int J Med Microbiol 2013 May 14;303(4):176-81. Epub 2013 Mar 14.

Center for Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany.

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May 2013

Fulminant Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis.

Laryngoscope 2013 Feb 30;123(2):362-5. Epub 2012 May 30.

Department of Otorhinolaryngology, Jena University Hospital, Jena, Germany.

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February 2013

Ex vivo transcriptional profiling reveals a common set of genes important for the adaptation of Pseudomonas aeruginosa to chronically infected host sites.

Environ Microbiol 2013 Feb 12;15(2):570-87. Epub 2012 Nov 12.

Institute for Molecular Bacteriology, Twincore, Center for Clinical and Experimental Infection Research, a joint venture of the Helmholtz Center of Infection Research and the Hannover Medical School, Hannover, 30625, Germany.

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February 2013

Presentation, etiology and outcome of pneumonia in younger nursing home residents.

J Infect 2012 Jul 10;65(1):32-8. Epub 2012 Feb 10.

Thoraxzentrum Ruhrgebiet, Department of Respiratory and Infectious Diseases, EVK Herne and Augusta-Kranken-Anstalt Bochum, Bergstrasse 26, 44791 Bochum, Germany.

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July 2012

Community-acquired pneumonia in younger patients is an entity on its own.

Eur Respir J 2012 May 16;39(5):1156-61. Epub 2011 Nov 16.

Thoraxzentrum Ruhrgebiet, Dept of Respiratory and Infectious Diseases, EVK Herne and Augusta-Kranken-Anstalt, Bochum, Germany.

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May 2012

Serum cortisol predicts death and critical disease independently of CRB-65 score in community-acquired pneumonia: a prospective observational cohort study.

BMC Infect Dis 2012 Apr 13;12:90. Epub 2012 Apr 13.

Division of Pulmonology, Medical Department 1, University Hospital Carl Gustav Carus, Fetscherstr. 74, 01307 Dresden, Germany.

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April 2012

Caspofungin for treatment of invasive aspergillosis in Germany: results of a pre-planned subanalysis of an international registry.

Eur J Med Res 2012 Apr 17;17. Epub 2012 Apr 17.

Ruprecht-Karls-Universität Heidelberg, Universitaetsklinikum, Medizinische Klinik Abteilung V, Heidelberg, Germany.

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April 2012

Potential cost-effectiveness and benefit-cost ratios of adult pneumococcal vaccination in Germany.

Health Econ Rev 2012 Mar 30;2(1). Epub 2012 Mar 30.

Centre for Health Economics, Königsworther Platz 1, Hannover, 30167, Germany.

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March 2012

Nursing-home-acquired pneumonia in Germany: an 8-year prospective multicentre study.

Thorax 2012 Feb 5;67(2):132-8. Epub 2011 Nov 5.

Thoraxzentrum Ruhrgebiet, Department of Respiratory and Infectious Diseases, EVK Herne and Augusta-Kranken-Anstalt Bochum, Germany.

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February 2012