Mathias Gautel

Mathias Gautel

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Mathias Gautel

Mathias Gautel

Publications by authors named "Mathias Gautel"

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Artifact-free high-density localization microscopy analysis.

Nat Methods 2018 09 30;15(9):689-692. Epub 2018 Jul 30.

Randall Centre for Cell and Molecular Biophysics, King's College London, London, UK.

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http://www.nature.com/articles/s41592-018-0072-5
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http://dx.doi.org/10.1038/s41592-018-0072-5DOI Listing
September 2018

Congenital myopathies: disorders of excitation-contraction coupling and muscle contraction.

Nat Rev Neurol 2018 03 2;14(3):151-167. Epub 2018 Feb 2.

The Dubowitz Neuromuscular Centre, Developmental Neurosciences Programme, UCL Great Ormond Street Institute of Child Health and Great Ormond Street Hospital for Children, London, UK.

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http://dx.doi.org/10.1038/nrneurol.2017.191DOI Listing
March 2018

TITINdb-a computational tool to assess titin's role as a disease gene.

Bioinformatics 2017 Nov;33(21):3482-3485

Randall Division of Cell and Molecular Biophysics, King's College London BHF Centre of Research Excellence, London SE1 1UL, UK.

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http://dx.doi.org/10.1093/bioinformatics/btx424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860166PMC
November 2017

Autopsy findings in EPG5-related Vici syndrome with antenatal onset.

Am J Med Genet A 2017 Sep 27;173(9):2522-2527. Epub 2017 Jul 27.

Department of Paediatric Neurology, Neuromuscular Service, Evelina's Children Hospital, Guy's & St. Thomas' Hospital NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1002/ajmg.a.38342DOI Listing
September 2017

Increasing evidence of mechanical force as a functional regulator in smooth muscle myosin light chain kinase.

Elife 2017 07 11;6. Epub 2017 Jul 11.

Chair for Applied Physics and Center for Nanoscience, Ludwig-Maximilians-Universität München, Munich, Germany.

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http://dx.doi.org/10.7554/eLife.26473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505704PMC
July 2017

Current and future therapeutic approaches to the congenital myopathies.

Semin Cell Dev Biol 2017 04 8;64:191-200. Epub 2016 Aug 8.

Randall Division for Cell and Molecular Biophysics, Muscle Signalling Section Biophysics and Cardiovascular Division, King's College BHF Centre of Research Excellence, United Kingdom.

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http://dx.doi.org/10.1016/j.semcdb.2016.08.004DOI Listing
April 2017

Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection.

Structure 2017 01 15;25(1):107-120. Epub 2016 Dec 15.

Randall Division of Cell and Molecular Biophysics, King's College London, London SE1 1UL, UK. Electronic address:

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http://dx.doi.org/10.1016/j.str.2016.11.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5222588PMC
January 2017

Reply: Aberrant splicing induced by the most common EPG5 mutation in an individual with Vici syndrome.

Brain 2016 09 24;139(Pt 9):e53. Epub 2016 Jun 24.

1 Department of Paediatric Neurology, Neuromuscular Service, Evelina's Children Hospital, Guy's & St. Thomas' Hospital NHS Foundation Trust, London, UK 3 Department of Clinical and Basic Neuroscience, IoPPN, King's College, London, UK 4 Randall Division of Cell and Molecular Biophysics, King's College London, British Heart Foundation Centre of Excellence, London, UK

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http://dx.doi.org/10.1093/brain/aww136DOI Listing
September 2016

Vici syndrome: a review.

Orphanet J Rare Dis 2016 Feb 29;11:21. Epub 2016 Feb 29.

Department of Paediatric Neurology, Neuromuscular Service, Evelina's Children Hospital, Guy's & St. Thomas' Hospital NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1186/s13023-016-0399-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772338PMC
February 2016

The sarcomeric cytoskeleton: from molecules to motion.

J Exp Biol 2016 Jan;219(Pt 2):135-45

Department of Structural and Computational Biology, Max F. Perutz Laboratories, University of Vienna, Campus Vienna Biocenter 5, Vienna A-1030, Austria Department of Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, Ljubljana 1000, Slovenia.

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http://dx.doi.org/10.1242/jeb.124941DOI Listing
January 2016

Epigenetic changes as a common trigger of muscle weakness in congenital myopathies.

Hum Mol Genet 2015 Aug 27;24(16):4636-47. Epub 2015 May 27.

Department of Biomedicine and Anesthesia, Basel University Hospital, Basel, Switzerland, Department of Life Sciences, General Pathology Section, University of Ferrara, Ferrara, Italy,

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http://dx.doi.org/10.1093/hmg/ddv195DOI Listing
August 2015

Solution NMR assignment of the heavy chain complex of the human cardiac myosin regulatory light chain.

Biomol NMR Assign 2015 Apr 12;9(1):51-3. Epub 2014 Jan 12.

Cardiovascular and Randall Division, King's College London, Guy's Campus, London, SE1 1UL, UK.

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http://dx.doi.org/10.1007/s12104-014-9543-5DOI Listing
April 2015

Titin ruler hypothesis not refuted.

Proc Natl Acad Sci U S A 2015 Mar 18;112(11):E1172. Epub 2015 Feb 18.

School of Molecular and Cellular Biology, Leeds University, Leeds LS2 9JT, United Kingdom; and

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http://dx.doi.org/10.1073/pnas.1422326112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371926PMC
March 2015

The crystal structure of the human titin:obscurin complex reveals a conserved yet specific muscle M-band zipper module.

J Mol Biol 2015 Feb 6;427(4):718-736. Epub 2014 Dec 6.

Randall Division of Cell and Molecular Biophysics, King's College London, New Hunt's House, Guy's Campus, London SE1 1UL, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2014.11.019DOI Listing
February 2015

Pathogenic mechanisms in centronuclear myopathies.

Front Aging Neurosci 2014 19;6:339. Epub 2014 Dec 19.

Randall Division of Cell and Molecular Biophysics and Cardiovascular Division, King's College London BHF Centre of Research Excellence , London , UK.

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http://dx.doi.org/10.3389/fnagi.2014.00339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271577PMC
January 2015

The structure and regulation of human muscle α-actinin.

Cell 2014 Dec 26;159(6):1447-60. Epub 2014 Nov 26.

Department of Structural and Computational Biology, Max F. Perutz Laboratories, University of Vienna, Campus Vienna Biocenter 5, 1030 Vienna, Austria; Department of Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Aškerčeva 5, 1000 Ljubljana, Slovenia. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.10.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259493PMC
December 2014

Myosin binding protein-C activates thin filaments and inhibits thick filaments in heart muscle cells.

Proc Natl Acad Sci U S A 2014 Dec 15;111(52):18763-8. Epub 2014 Dec 15.

Randall Division of Cell and Molecular Biophysics and British Heart Foundation Centre of Research Excellence, King's College London, London SE1 1UL, United Kingdom

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http://dx.doi.org/10.1073/pnas.1413922112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4284530PMC
December 2014

Reply: Hereditary myopathy with early respiratory failure is caused by mutations in the titin FN3 119 domain.

Brain 2014 Jun 24;137(Pt 6):e279. Epub 2014 Feb 24.

4 Randall Division for Cell and Molecular Biophysics and Cardiovascular Division, King's College London, London, UK

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http://dx.doi.org/10.1093/brain/awu033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032095PMC
June 2014

Clinical utility gene card for: Vici Syndrome.

Eur J Hum Genet 2014 Mar 10;22(3). Epub 2013 Jul 10.

1] Randall Division for Cell and Molecular Biophysics, King's College, London, UK [2] Department of Paediatric Neurology, Evelina Children's Hospital, Guy's and St. Thomas' NHS Foundation Trust, London, UK [3] Clinical Neuroscience Division, IoP, King's College, London, UK.

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http://dx.doi.org/10.1038/ejhg.2013.142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925270PMC
March 2014

Phosphoregulation of the titin-cap protein telethonin in cardiac myocytes.

J Biol Chem 2014 Jan 26;289(3):1282-93. Epub 2013 Nov 26.

From the Cardiovascular Division, King's College London British Heart Foundation Centre, London SE1 7EH, United Kingdom.

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http://dx.doi.org/10.1074/jbc.M113.479030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3894314PMC
January 2014

Diggin' on u(biquitin): a novel method for the identification of physiological E3 ubiquitin ligase substrates.

Cell Biochem Biophys 2013 Sep;67(1):127-38

Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7126, USA.

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http://dx.doi.org/10.1007/s12013-013-9624-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3758785PMC
September 2013

Developmental regulation of MURF E3 ubiquitin ligases in skeletal muscle.

J Muscle Res Cell Motil 2012 Jun 17;33(2):107-22. Epub 2012 Mar 17.

Cardiovascular Division, BHF Centre of Research Excellence, King's College London, London, UK.

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http://dx.doi.org/10.1007/s10974-012-9288-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353113PMC
June 2012

The sarcomeric cytoskeleton as a target for pharmacological intervention.

Curr Opin Pharmacol 2012 Jun 4;12(3):347-54. Epub 2012 Apr 4.

King's College London BHF Centre of Research Excellence, Randall Division for Cell and Molecular Biophysics and Cardiovascular Division, New Hunt's House, Guy's Campus, London SE1 1UL, United Kingdom.

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http://dx.doi.org/10.1016/j.coph.2012.03.007DOI Listing
June 2012

Structure, interactions and function of the N-terminus of cardiac myosin binding protein C (MyBP-C): who does what, with what, and to whom?

J Muscle Res Cell Motil 2012 May 20;33(1):83-94. Epub 2012 Apr 20.

Randall Division for Cell and Molecular Biophysics and Cardiovascular Division, King's College London BHF Centre of Research Excellence, London, UK.

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http://dx.doi.org/10.1007/s10974-012-9291-zDOI Listing
May 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan Theocharis Panaretakis Udai Bhan Pandey Zuzana Papackova Issidora Papassideri Irmgard Paris Junsoo Park Ohkmae K Park Jan B Parys Katherine R Parzych Susann Patschan Cam Patterson Sophie Pattingre John M Pawelek Jianxin Peng David H Perlmutter Ida Perrotta George Perry Shazib Pervaiz Matthias Peter Godefridus J Peters Morten Petersen Goran Petrovski James M Phang Mauro Piacentini Philippe Pierre Valérie Pierrefite-Carle Gérard Pierron Ronit Pinkas-Kramarski Antonio Piras Natik Piri Leonidas C Platanias Stefanie Pöggeler Marc Poirot Angelo Poletti Christian Poüs Mercedes Pozuelo-Rubio Mette Prætorius-Ibba Anil Prasad Mark Prescott Muriel Priault Nathalie Produit-Zengaffinen Ann Progulske-Fox Tassula Proikas-Cezanne Serge Przedborski Karin Przyklenk Rosa Puertollano Julien Puyal Shu-Bing Qian Liang Qin Zheng-Hong Qin Susan E Quaggin Nina Raben Hannah Rabinowich Simon W Rabkin Irfan Rahman Abdelhaq Rami Georg Ramm Glenn Randall Felix Randow V Ashutosh Rao Jeffrey C Rathmell Brinda 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Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang 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Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

Autophagy 2012 Apr;8(4):445-544

Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3404883PMC
http://dx.doi.org/10.4161/auto.19496DOI Listing
April 2012

Cytoskeletal protein kinases: titin and its relations in mechanosensing.

Authors:
Mathias Gautel

Pflugers Arch 2011 Jul 18;462(1):119-34. Epub 2011 Mar 18.

King's College London BHF Centre of Research Excellence, Cardiovascular Division, London, SE1 1UL, UK.

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July 2011

Transcriptional mechanisms regulating skeletal muscle differentiation, growth and homeostasis.

Nat Rev Mol Cell Biol 2011 Jun;12(6):349-61

Max-Planck-Institute for Heart and Lung Research, Department for Cardiac Development and Remodelling, Benekestrasse, Bad Nauheim, Germany. thomas.braun@ mpi-bn.mpg.de

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June 2011

Structure and interactions of myosin-binding protein C domain C0: cardiac-specific regulation of myosin at its neck?

J Biol Chem 2011 Apr 5;286(14):12650-8. Epub 2011 Feb 5.

Department of Biochemistry, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.

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April 2011

Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover.

Dev Biol 2011 Mar 23;351(1):46-61. Epub 2010 Dec 23.

King's College London BHF Centre of Research Excellence, Randall Division for Cell and Molecular Biophysics and Cardiovascular Division, New Hunt's House, Guy's Campus, London SE1 1UL, UK.

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March 2011

The sarcomeric cytoskeleton: who picks up the strain?

Authors:
Mathias Gautel

Curr Opin Cell Biol 2011 Feb 27;23(1):39-46. Epub 2010 Dec 27.

King's College London BHF Centre of Research Excellence, Cardiovascular Division and Randall Division for Cell and Molecular Biophysics, London SE1 1UL, United Kingdom.

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February 2011

Cell biology. Gett'N-WASP stripes.

Science 2010 Dec;330(6010):1491-2

King's College London British Heart Foundation Centre of Research Excellence, Cardiovascular Division, London, SE1 1UL, UK.

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December 2010

Structural insight into M-band assembly and mechanics from the titin-obscurin-like-1 complex.

Proc Natl Acad Sci U S A 2010 Feb 1;107(7):2908-13. Epub 2010 Feb 1.

King's College London BHF Research Excellence Centre, Randall Division for Cell and Molecular Biophysics and Cardiovascular Division, New Hunt's House, Guy's Campus, London SE1 1UL, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814874PMC
February 2010

Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover.

FEBS Lett 2009 Jun 8;583(12):1846-52. Epub 2009 May 8.

King's College London, Department of Medical and Molecular Genetics, London, UK.

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http://dx.doi.org/10.1016/j.febslet.2009.04.049DOI Listing
June 2009

The sarcomere and sarcomerogenesis.

Adv Exp Med Biol 2008 ;642:1-14

Cardiovascular Division, King's College London, London, UK.

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February 2009

The sarcomere and the nucleus: functional links to hypertrophy, atrophy and sarcopenia.

Authors:
Mathias Gautel

Adv Exp Med Biol 2008 ;642:176-91

Cardiovascular Division, King's College London, London, UK.

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February 2009

Myosin binding protein C positioned to play a key role in regulation of muscle contraction: structure and interactions of domain C1.

J Mol Biol 2008 Dec 7;384(3):615-30. Epub 2008 Oct 7.

Department of Biochemistry, University of Leicester, Lancaster Road, Leicester LE1 9HN, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631168PMC
December 2008

Mechanoenzymatics of titin kinase.

Proc Natl Acad Sci U S A 2008 Sep 2;105(36):13385-90. Epub 2008 Sep 2.

Chair for Applied Physics, Center for Integrated Protein Science Munich and Center for Nanoscience, Ludwig-Maximilians-Universität München, 80799 Munich, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527993PMC
September 2008

Comparing proteins by their unfolding pattern.

Biophys J 2008 Jul;95(1):426-34

Lehrstuhl für Angewandte Physik and Center for Nanoscience, LMU München, Munich, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2426622PMC
July 2008

Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies.

J Cell Sci 2008 Jun 13;121(11):1841-51. Epub 2008 May 13.

King's College London, The Randall Division for Cell and Molecular Biophysics, and Cardiovascular Division, New Hunt's House, London, UK.

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June 2008

Rigid conformation of an immunoglobulin domain tandem repeat in the A-band of the elastic muscle protein titin.

J Mol Biol 2007 Aug 25;371(2):469-80. Epub 2007 May 25.

EMBL Hamburg Outstation, c/o DESY, Notkestrasse 85, D-22603 Hamburg, Germany.

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August 2007

Dissecting the N-terminal myosin binding site of human cardiac myosin-binding protein C. Structure and myosin binding of domain C2.

J Biol Chem 2007 Mar 27;282(12):9204-15. Epub 2006 Dec 27.

Department of Biochemistry, University of Leicester, University Road, Leicester LE1 7RH.

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March 2007

Complete human gene structure of obscurin: implications for isoform generation by differential splicing.

J Muscle Res Cell Motil 2005 ;26(6-8):427-34

The Randall Division of Cell and Molecular Biophysics and The Cardiovascular Division, New Hunt's House, King's College London, SE1 1UL, London, United Kingdom.

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January 2007

Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment.

Proc Natl Acad Sci U S A 2006 Nov 9;103(47):17713-7. Epub 2006 Nov 9.

Max Planck Institute of Molecular Physiology, Department of Physical Biochemistry, 44227 Dortmund, Germany.

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November 2006

Targeted homozygous deletion of M-band titin in cardiomyocytes prevents sarcomere formation.

J Cell Sci 2006 Oct;119(Pt 20):4322-31

Institute for Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.

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October 2006

Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus.

J Struct Biol 2006 Aug 27;155(2):239-50. Epub 2006 Apr 27.

EMBL-Hamburg, c/o DESY, Notkeststrasse 85, D-22603 Hamburg, Germany.

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August 2006

From A to Z and back? Multicompartment proteins in the sarcomere.

Trends Cell Biol 2006 Jan 6;16(1):11-8. Epub 2005 Dec 6.

King's College London, Muscle Signalling and Development, The Randall Division of Cell and Molecular Biophysics, New Hunt's House, London SE1 1UL, UK.

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January 2006

Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk.

Nature 2006 Jan;439(7073):229-33

EMBL-Hamburg c/o DESY, Notkeststrasse 85, D-22603 Hamburg, Germany.

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http://dx.doi.org/10.1038/nature04343DOI Listing
January 2006

The crystal structure of the actin binding domain from alpha-actinin in its closed conformation: structural insight into phospholipid regulation of alpha-actinin.

J Mol Biol 2005 Apr;348(1):151-65

Structural Biology Laboratory, Elettra-Sincrotrone Trieste in Area Science Park, S.S. 14 Km 163,5 34012 Trieste, Italy.

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April 2005

Mechanically induced titin kinase activation studied by force-probe molecular dynamics simulations.

Biophys J 2005 Feb 5;88(2):790-804. Epub 2004 Nov 5.

Theoretical and Computational Biophysics Department, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.

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http://dx.doi.org/10.1529/biophysj.104.052423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1305156PMC
February 2005

Protein kinase D is a novel mediator of cardiac troponin I phosphorylation and regulates myofilament function.

Circ Res 2004 Nov 28;95(11):1091-9. Epub 2004 Oct 28.

Cardiovascular Division, King's College London, London, UK.

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http://dx.doi.org/10.1161/01.RES.0000149299.34793.3cDOI Listing
November 2004

Binding of myosin binding protein-C to myosin subfragment S2 affects contractility independent of a tether mechanism.

Circ Res 2004 Oct 7;95(9):930-6. Epub 2004 Oct 7.

Department of Bioengineering, Box 357962, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1161/01.RES.0000147312.02673.56DOI Listing
October 2004

The elasticity of single titin molecules using a two-bead optical tweezers assay.

Biophys J 2004 Aug;87(2):1112-35

Medical Research Council Muscle and Cell Motility Unit, King's College London, London SE1 1UL, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1304451PMC
August 2004

Association of the chaperone alphaB-crystallin with titin in heart muscle.

J Biol Chem 2004 Feb 4;279(9):7917-24. Epub 2003 Dec 4.

European Molecular Biology Laboratory, Meyerhofstrasse 1, D-69117 Heidelberg, Germany.

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February 2004

Myofibrillar tightly bound calcium in skeletal muscle fibers: a possible role of this cation in titin strands aggregation.

FEBS Lett 2004 Jan;556(1-3):271-5

Muscle Biochemistry Group, INRA (Institut National de la Recherche Agronomique)-Theix, 63122, Saint Genès Champanelle, France.

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http://dx.doi.org/10.1016/s0014-5793(03)01436-4DOI Listing
January 2004

Solution scattering suggests cross-linking function of telethonin in the complex with titin.

J Biol Chem 2003 Jan 20;278(4):2636-44. Epub 2002 Nov 20.

European Molecular Biology Laboratory (EMBL), Hamburg Outstation, EMBL c/o Deutsches Electronen- Synchrotron (DESY), Notkestrasse 85, Germany.

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http://dx.doi.org/10.1074/jbc.M210217200DOI Listing
January 2003

PEVK domain of titin: an entropic spring with actin-binding properties.

J Struct Biol 2002 Jan-Feb;137(1-2):194-205

Institute of Physiology and Pathophysiology, University of Heidelberg, Germany.

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http://dx.doi.org/10.1006/jsbi.2002.4468DOI Listing
December 2002

Transient association of titin and myosin with microtubules in nascent myofibrils directed by the MURF2 RING-finger protein.

J Cell Sci 2002 Dec;115(Pt 23):4469-82

European Molecular Biology Laboratory, Cell Biology Division, Heidelberg, Germany.

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http://dx.doi.org/10.1242/jcs.00131DOI Listing
December 2002

The spectrin repeat: a structural platform for cytoskeletal protein assemblies.

FEBS Lett 2002 Feb;513(1):119-23

Structural Biology Laboratory, Sincrotrone Trieste in Area Science Park, S.S. 14 Km 163,5, 34012 Trieste, Italy.

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February 2002