Publications

Inhibition of TRF1 Telomere Protein Impairs Tumor Initiation and Progression in Glioblastoma Mouse Models and Patient-Derived Xenografts.
Cancer Cell 2017 Nov;32(5):590-607.e4
Telomeres and Telomerase Group, Molecular Oncology Program, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, Madrid, 28029, Spain. Electronic address:

Glioblastoma and glioblastoma stem cells are dependent on functional MTH1.
Oncotarget 2017 Oct 20;8(49):84671-84684. Epub 2017 Jul 20.
Department of Medical Biochemistry and Biophysics, Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Karolinska Institutet, Stockholm, Sweden.

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.
Cancer Cell 2017 Jul;32(1):42-56.e6
Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA. Electronic address:

Targeting tyrosine receptor kinase B in gliomas.
Neuro Oncol 2017 Jan 14;19(1):138-139. Epub 2016 Sep 14.
Cancer and Neurobiology Laboratory, Experimental Research Center, Clinical Hospital (CPE-HCPA), Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., G.S., C.B.F., R.R.); Department of Pharmacology, Institute for Basic Health Sciences, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (K.V.P., C.A., M.B., M.S.G., A.T., R.R.); Department of Internal Medicine, Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (G.S.), Children's Cancer Institute, Porto Alegre, Brazil (C.B.F.).

GlioVis data portal for visualization and analysis of brain tumor expression datasets.
Neuro Oncol 2017 Jan 9;19(1):139-141. Epub 2016 Nov 9.
Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA (R.L.B.); Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA (Q.W., R.G.V.); Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA (Q.W.); Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA (Q.W., R.G.V.); Bioinformatics unit, Structural Biology and Biocomputing Programme, Centro Nacional de Investigaciones Oncológicas, CNIO, Madrid, Spain (A.C.); Department of Computational Biology, The Jackson Laboratory, Farmington, Connecticut, USA (R.G.V.); Seve Ballesteros Foundation Brain Tumor Group, Cancer Cell Biology Programme, Centro Nacional de Investigaciones Oncológicas, CNIO, Madrid, Spain (M.S.)

Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma.
Cancer Cell 2014 Aug;26(2):288-300
Division of Human Biology and Solid Tumor Translational Research, Fred Hutchinson Cancer Research Center, Department of Neurosurgery and Alvord Brain Tumor Center, University of Washington, Seattle, WA 98109, USA. Electronic address:

Histone acetyltransferase PCAF is required for Hedgehog-Gli-dependent transcription and cancer cell proliferation.
Cancer Res 2013 Oct 13;73(20):6323-33. Epub 2013 Aug 13.
Authors' Affiliations: Biotech Research and Innovation Centre (BRIC) and Centre for Epigenetics, University of Copenhagen; The Danish Stem Cell Center (Danstem), Copenhagen, Denmark; and F-BBVA Cancer Cell Biology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid, Spain.

An essential role for p38 MAPK in cerebellar granule neuron precursor proliferation.
Acta Neuropathol 2012 Apr;123(4):573-86
Departments of Neurological Surgery and Cancer Biology, Vanderbilt University, Nashville, TN, 37212, USA; Department of Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, NY, 10065, USA.



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