Massimo Serra

Massimo Serra

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Massimo Serra

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An update on emerging drugs in osteosarcoma: towards tailored therapies?

Expert Opin Emerg Drugs 2019 Aug 14:1-19. Epub 2019 Aug 14.

a Laboratory of Experimental Oncology, Pharmacogenomics and Pharmacogenetics Research Unit, IRCCS Istituto Ortopedico Rizzoli , Bologna , Italy.

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http://dx.doi.org/10.1080/14728214.2019.1654455DOI Listing
August 2019

Current understanding of pharmacogenetic implications of DNA damaging drugs used in osteosarcoma treatment.

Expert Opin Drug Metab Toxicol 2019 Apr 18;15(4):299-311. Epub 2019 Mar 18.

a Pharmacogenomics and Pharmacogenetics Research Unit of the Laboratory of Experimental Oncology , IRCCS Istituto Ortopedico Rizzoli , Bologna , Italy.

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http://dx.doi.org/10.1080/17425255.2019.1588885DOI Listing
April 2019

Prenylated Curcumin Analogues as Multipotent Tools To Tackle Alzheimer's Disease.

ACS Chem Neurosci 2019 Mar 2;10(3):1420-1433. Epub 2019 Jan 2.

Department of Pharmacy and Biotechnology , Alma Mater Studiorum-University of Bologna , Via Belmeloro 6 , 40126 Bologna , Italy.

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http://dx.doi.org/10.1021/acschemneuro.8b00463DOI Listing
March 2019

Endoplasmic reticulum-targeting doxorubicin: a new tool effective against doxorubicin-resistant osteosarcoma.

Cell Mol Life Sci 2019 Feb 14;76(3):609-625. Epub 2018 Nov 14.

Department of Oncology, University of Torino, Via Santena 5/bis, 10126, Torino, Italy.

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http://dx.doi.org/10.1007/s00018-018-2967-9DOI Listing
February 2019

An RGD small-molecule integrin antagonist induces detachment-mediated anoikis in glioma cancer stem cells.

Int J Oncol 2018 Dec 3;53(6):2683-2694. Epub 2018 Oct 3.

Department of Drug Sciences, University of Pavia, I-27100 Pavia, Italy.

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http://dx.doi.org/10.3892/ijo.2018.4583DOI Listing
December 2018

Genetic testing for high-grade osteosarcoma: a guide for future tailored treatments?

Expert Rev Mol Diagn 2018 11 19;18(11):947-961. Epub 2018 Oct 19.

a Laboratory of Experimental Oncology , IRCCS Istituto Ortopedico Rizzoli , Bologna , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14737159.2018.1
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http://dx.doi.org/10.1080/14737159.2018.1535903DOI Listing
November 2018

Functionalized Keratin as Nanotechnology-Based Drug Delivery System for the Pharmacological Treatment of Osteosarcoma.

Int J Mol Sci 2018 Nov 20;19(11). Epub 2018 Nov 20.

Institute of Organic Synthesis and Photoreactivity (ISOF), National Research Council (CNR), Via Gobetti, 101, 40129 Bologna, Italy.

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http://dx.doi.org/10.3390/ijms19113670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274803PMC
November 2018

Agave negatively regulates YAP and TAZ transcriptionally and post-translationally in osteosarcoma cell lines.

Cancer Lett 2018 10 19;433:18-32. Epub 2018 Jun 19.

Oncogenomic and Epigenetic Unit, Molecular Chemoprevention Group, Department of Research, Diagnosis and Innovative Technologies, Translational Research Area, Regina Elena National Cancer Institute, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2018.06.021DOI Listing
October 2018

Synthesis of Variously Functionalized Azabicycloalkane Scaffolds by Domino Metathesis Reactions.

J Org Chem 2017 10 4;82(20):11091-11101. Epub 2017 Oct 4.

Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia , Viale Taramelli 12, 27100 Pavia, Italy.

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http://dx.doi.org/10.1021/acs.joc.7b02047DOI Listing
October 2017

Doxorubicin-resistant osteosarcoma: novel therapeutic approaches in sight?

Future Oncol 2017 04 10;13(8):673-677. Epub 2017 Feb 10.

Pharmacogenomics & Pharmacogenetics Research Unit, Laboratory of Experimental Oncology, Orthopaedic Rizzoli Institute, via di Barbiano 1/10, 40136 Bologna, Italy.

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http://dx.doi.org/10.2217/fon-2016-0519DOI Listing
April 2017

Pharmacogenomics of genes involved in antifolate drug response and toxicity in osteosarcoma.

Expert Opin Drug Metab Toxicol 2017 Mar 19;13(3):245-257. Epub 2016 Oct 19.

a Pharmacogenomics and Pharmacogenetics Research Unit, Laboratory of Experimental Oncology , Orthopaedic Rizzoli Institute , Bologna , Italy.

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http://dx.doi.org/10.1080/17425255.2017.1246532DOI Listing
March 2017

Polymorphisms of genes related to metotrexate response and toxicity in high-grade osteosarcoma.

Expert Opin Drug Metab Toxicol 2017 01 21;13(1):123. Epub 2016 Nov 21.

a Pharmacogenomics and Pharmacogenetics Research Unit, Laboratory of Experimental Oncology , Orthopaedic Rizzoli Institute , Bologna , Italy.

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http://dx.doi.org/10.1080/17425255.2017.1260300DOI Listing
January 2017

Pharmacogenomics of second-line drugs used for treatment of unresponsive or relapsed osteosarcoma patients.

Pharmacogenomics 2016 Dec 24;17(18):2097-2114. Epub 2016 Nov 24.

Pharmacogenomics & Pharmacogenetics Research Unit of the Laboratory of Experimental Oncology, Orthopaedic Rizzoli Institute, Via di Barbiano 1/10, I-40136 Bologna, Italy.

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http://dx.doi.org/10.2217/pgs-2016-0116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558522PMC
December 2016

Targeting ABCB1 and ABCC1 with their Specific Inhibitor CBT-1® can Overcome Drug Resistance in Osteosarcoma.

Curr Cancer Drug Targets 2016 ;16(3):261-74

Pharmacogenomics and Pharmacogenetics Research Unit, Laboratory of Experimental Oncology, Orthopaedic Rizzoli Institute, Via di Barbiano 1/10, I-40136 Bologna, Italy.

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November 2016

Integrins in glioblastoma: Still an attractive target?

Pharmacol Res 2016 11 3;113(Pt A):55-61. Epub 2016 Aug 3.

Department of Drug Sciences, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1016/j.phrs.2016.08.004DOI Listing
November 2016

An update on chemotherapy for osteosarcoma.

Expert Opin Pharmacother 2015 29;16(18):2727-36. Epub 2015 Oct 29.

b Laboratory of Experimental Oncology , Rizzoli Orthopaedic Institute , Via Pupilli 1, Bologna 40136 , Italy.

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http://dx.doi.org/10.1517/14656566.2015.1102226DOI Listing
June 2016

Role of pharmacogenetics of drug-metabolizing enzymes in treating osteosarcoma.

Expert Opin Drug Metab Toxicol 2015 25;11(9):1449-63. Epub 2015 Jun 25.

a Orthopaedic Rizzoli Institute, Laboratory of Experimental Oncology, Pharmacogenomics and Pharmacogenetics Research Unit , Via di Barbiano 1/10, I-40136 Bologna, Italy +390 516 366 762 ; +390 516 366 763 ;

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http://dx.doi.org/10.1517/17425255.2015.1060220DOI Listing
May 2016

H2S-Donating Doxorubicins May Overcome Cardiotoxicity and Multidrug Resistance.

J Med Chem 2016 05 5;59(10):4881-9. Epub 2016 May 5.

Department of Science and Drug Technology, University of Torino , via Pietro Giuria 9, 10125 Torino, Italy.

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http://dx.doi.org/10.1021/acs.jmedchem.6b00184DOI Listing
May 2016

Analysis of Heritability and Shared Heritability Based on Genome-Wide Association Studies for Thirteen Cancer Types.

Authors:
Joshua N Sampson William A Wheeler Meredith Yeager Orestis Panagiotou Zhaoming Wang Sonja I Berndt Qing Lan Christian C Abnet Laufey T Amundadottir Jonine D Figueroa Maria Teresa Landi Lisa Mirabello Sharon A Savage Philip R Taylor Immaculata De Vivo Katherine A McGlynn Mark P Purdue Preetha Rajaraman Hans-Olov Adami Anders Ahlbom Demetrius Albanes Maria Fernanda Amary She-Juan An Ulrika Andersson Gerald Andriole Irene L Andrulis Emanuele Angelucci Stephen M Ansell Cecilia Arici Bruce K Armstrong Alan A Arslan Melissa A Austin Dalsu Baris Donald A Barkauskas Bryan A Bassig Nikolaus Becker Yolanda Benavente Simone Benhamou Christine Berg David Van Den Berg Leslie Bernstein Kimberly A Bertrand Brenda M Birmann Amanda Black Heiner Boeing Paolo Boffetta Marie-Christine Boutron-Ruault Paige M Bracci Louise Brinton Angela R Brooks-Wilson H Bas Bueno-de-Mesquita Laurie Burdett Julie Buring Mary Ann Butler Qiuyin Cai Geraldine Cancel-Tassin Federico Canzian Alfredo Carrato Tania Carreon Angela Carta John K C Chan Ellen T Chang Gee-Chen Chang I-Shou Chang Jiang Chang Jenny Chang-Claude Chien-Jen Chen Chih-Yi Chen Chu Chen Chung-Hsing Chen Constance Chen Hongyan Chen Kexin Chen Kuan-Yu Chen Kun-Chieh Chen Ying Chen Ying-Hsiang Chen Yi-Song Chen Yuh-Min Chen Li-Hsin Chien María-Dolores Chirlaque Jin Eun Choi Yi Young Choi Wong-Ho Chow Charles C Chung Jacqueline Clavel Françoise Clavel-Chapelon Pierluigi Cocco Joanne S Colt Eva Comperat Lucia Conde Joseph M Connors David Conti Victoria K Cortessis Michelle Cotterchio Wendy Cozen Simon Crouch Marta Crous-Bou Olivier Cussenot Faith G Davis Ti Ding W Ryan Diver Miren Dorronsoro Laure Dossus Eric J Duell Maria Grazia Ennas Ralph L Erickson Maria Feychting Adrienne M Flanagan Lenka Foretova Joseph F Fraumeni Neal D Freedman Laura E Beane Freeman Charles Fuchs Manuela Gago-Dominguez Steven Gallinger Yu-Tang Gao Susan M Gapstur Montserrat Garcia-Closas Reina García-Closas Randy D Gascoyne Julie Gastier-Foster Mia M Gaudet J Michael Gaziano Carol Giffen Graham G Giles Edward Giovannucci Bengt Glimelius Michael Goggins Nalan Gokgoz Alisa M Goldstein Richard Gorlick Myron Gross Robert Grubb Jian Gu Peng Guan Marc Gunter Huan Guo Thomas M Habermann Christopher A Haiman Dina Halai Goran Hallmans Manal Hassan Claudia Hattinger Qincheng He Xingzhou He Kathy Helzlsouer Brian Henderson Roger Henriksson Henrik Hjalgrim Judith Hoffman-Bolton Chancellor Hohensee Theodore R Holford Elizabeth A Holly Yun-Chul Hong Robert N Hoover Pamela L Horn-Ross G M Monawar Hosain H Dean Hosgood Chin-Fu Hsiao Nan Hu Wei Hu Zhibin Hu Ming-Shyan Huang Jose-Maria Huerta Jen-Yu Hung Amy Hutchinson Peter D Inskip Rebecca D Jackson Eric J Jacobs Mazda Jenab Hyo-Sung Jeon Bu-Tian Ji Guangfu Jin Li Jin Christoffer Johansen Alison Johnson Yoo Jin Jung Rudolph Kaaks Aruna Kamineni Eleanor Kane Chang Hyun Kang Margaret R Karagas Rachel S Kelly Kay-Tee Khaw Christopher Kim Hee Nam Kim Jin Hee Kim Jun Suk Kim Yeul Hong Kim Young Tae Kim Young-Chul Kim Cari M Kitahara Alison P Klein Robert J Klein Manolis Kogevinas Takashi Kohno Laurence N Kolonel Charles Kooperberg Anne Kricker Vittorio Krogh Hideo Kunitoh Robert C Kurtz Sun-Seog Kweon Andrea LaCroix Charles Lawrence Fernando Lecanda Victor Ho Fun Lee Donghui Li Haixin Li Jihua Li Yao-Jen Li Yuqing Li Linda M Liao Mark Liebow Tracy Lightfoot Wei-Yen Lim Chien-Chung Lin Dongxin Lin Sara Lindstrom Martha S Linet Brian K Link Chenwei Liu Jianjun Liu Li Liu Börje Ljungberg Josep Lloreta Simonetta Di Lollo Daru Lu Eiluv Lund Nuria Malats Satu Mannisto Loic Le Marchand Neyssa Marina Giovanna Masala Giuseppe Mastrangelo Keitaro Matsuo Marc Maynadie James McKay Roberta McKean-Cowdin Mads Melbye Beatrice S Melin Dominique S Michaud Tetsuya Mitsudomi Alain Monnereau Rebecca Montalvan Lee E Moore Lotte Maxild Mortensen Alexandra Nieters Kari E North Anne J Novak Ann L Oberg Kenneth Offit In-Jae Oh Sara H Olson Domenico Palli William Pao In Kyu Park Jae Yong Park Kyong Hwa Park Ana Patiño-Garcia Sofia Pavanello Petra H M Peeters Reury-Perng Perng Ulrike Peters Gloria M Petersen Piero Picci Malcolm C Pike Stefano Porru Jennifer Prescott Ludmila Prokunina-Olsson Biyun Qian You-Lin Qiao Marco Rais Elio Riboli Jacques Riby Harvey A Risch Cosmeri Rizzato Rebecca Rodabough Eve Roman Morgan Roupret Avima M Ruder Silvia de Sanjose Ghislaine Scelo Alan Schned Fredrick Schumacher Kendra Schwartz Molly Schwenn Katia Scotlandi Adeline Seow Consol Serra Massimo Serra Howard D Sesso Veronica Wendy Setiawan Gianluca Severi Richard K Severson Tait D Shanafelt Hongbing Shen Wei Shen Min-Ho Shin Kouya Shiraishi Xiao-Ou Shu Afshan Siddiq Luis Sierrasesúmaga Alan Dart Loon Sihoe Christine F Skibola Alex Smith Martyn T Smith Melissa C Southey John J Spinelli Anthony Staines Meir Stampfer Marianna C Stern Victoria L Stevens Rachael S Stolzenberg-Solomon Jian Su Wu-Chou Su Malin Sund Jae Sook Sung Sook Whan Sung Wen Tan Wei Tang Adonina Tardón David Thomas Carrie A Thompson Lesley F Tinker Roberto Tirabosco Anne Tjønneland Ruth C Travis Dimitrios Trichopoulos Fang-Yu Tsai Ying-Huang Tsai Margaret Tucker Jenny Turner Claire M Vajdic Roel C H Vermeulen Danylo J Villano Paolo Vineis Jarmo Virtamo Kala Visvanathan Jean Wactawski-Wende Chaoyu Wang Chih-Liang Wang Jiu-Cun Wang Junwen Wang Fusheng Wei Elisabete Weiderpass George J Weiner Stephanie Weinstein Nicolas Wentzensen Emily White Thomas E Witzig Brian M Wolpin Maria Pik Wong Chen Wu Guoping Wu Junjie Wu Tangchun Wu Wei Wu Xifeng Wu Yi-Long Wu Jay S Wunder Yong-Bing Xiang Jun Xu Ping Xu Pan-Chyr Yang Tsung-Ying Yang Yuanqing Ye Zhihua Yin Jun Yokota Ho-Il Yoon Chong-Jen Yu Herbert Yu Kai Yu Jian-Min Yuan Andrew Zelenetz Anne Zeleniuch-Jacquotte Xu-Chao Zhang Yawei Zhang Xueying Zhao Zhenhong Zhao Hong Zheng Tongzhang Zheng Wei Zheng Baosen Zhou Meng Zhu Mariagrazia Zucca Simina M Boca James R Cerhan Giovanni M Ferri Patricia Hartge Chao Agnes Hsiung Corrado Magnani Lucia Miligi Lindsay M Morton Karin E Smedby Lauren R Teras Joseph Vijai Sophia S Wang Paul Brennan Neil E Caporaso David J Hunter Peter Kraft Nathaniel Rothman Debra T Silverman Susan L Slager Stephen J Chanock Nilanjan Chatterjee

J Natl Cancer Inst 2015 Dec 12;107(12):djv279. Epub 2015 Oct 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD (JNS, OP, SIB, QL, CCA, LTA, JDF, MTL, LM, SAS, PRT, KAM, PR, DA, DB, BAB, AB, LBr, WHC, CCC, JSC, JFFJr, NDF, LEBF, MGC, AMG, RNH, NH, WH, PDI, BTJ, CK, CMK, LML, MSL, LEM, LPO, RSSS, WeiT, MT, CWa, SW, NW, KY, PH, LMM, NEC, NR, DTS, SJC, NC); Information Management Services, Silver Spring, MD (WAW, CG); Cancer Genomics Research Laboratory, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Gaithersburg, MD (MY, ZW, LBu, AH, CLi); Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (IDV, KAB, BMB, CoC, MCB, CF, EG, SL, JP, MSt, DJH); Department of Epidemiology, Harvard School of Public Health, Boston, MA (IDV, OA, KAB, CoC, MCB, EG, RSK, SL, JP, HDS, MSt, DTr, DJH, PK); Ontario Health Study, Toronto, Ontario, Canada (MPP); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (HOA, EWe); Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (AA, MF); UCL Cancer Institute, London, UK (MFA, AMF, DH); Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex, UK (MFA, AMF, DH, RT); Guangdong Lung Cancer Institute, Guangdong Provincial Key Laboratory of Translational Medicine in Lung Cancer, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China (SJA, JS, YLW, XCZ); Department of Radiation Sciences, Oncology, Umea University, Umea, Sweden (UA, RH, BSM); Division of Urologic Surgery, Washington University School of Medicine, Saint Louis, MO (GAJr, RGIII); Litwin Centre for Cancer Genetics, University of Toronto, Ontario, Canada (ILA, NG, JSW); Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada (ILA, SG, NG, JSW); Hematology Unit, Ospedale Oncologico di Riferimento Regionale A. Businco, Cagliari, Italy (EA); Department of Medicin

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http://kooperberg.fhcrc.org/papers/2015sampson.pdf
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http://jnci.oxfordjournals.org/lookup/doi/10.1093/jnci/djv27
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http://dx.doi.org/10.1093/jnci/djv279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4806328PMC
December 2015

Advances in emerging drugs for osteosarcoma.

Expert Opin Emerg Drugs 2015 Sep 1;20(3):495-514. Epub 2015 Jun 1.

a 1 Rizzoli Orthopaedic Institute, Laboratory of Experimental Oncology , Bologna, Italy.

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http://dx.doi.org/10.1517/14728214.2015.1051965DOI Listing
September 2015

Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.

Authors:
Zhaoming Wang Bin Zhu Mingfeng Zhang Hemang Parikh Jinping Jia Charles C Chung Joshua N Sampson Jason W Hoskins Amy Hutchinson Laurie Burdette Abdisamad Ibrahim Christopher Hautman Preethi S Raj Christian C Abnet Andrew A Adjei Anders Ahlbom Demetrius Albanes Naomi E Allen Christine B Ambrosone Melinda Aldrich Pilar Amiano Christopher Amos Ulrika Andersson Gerald Andriole Irene L Andrulis Cecilia Arici Alan A Arslan Melissa A Austin Dalsu Baris Donald A Barkauskas Bryan A Bassig Laura E Beane Freeman Christine D Berg Sonja I Berndt Pier Alberto Bertazzi Richard B Biritwum Amanda Black William Blot Heiner Boeing Paolo Boffetta Kelly Bolton Marie-Christine Boutron-Ruault Paige M Bracci Paul Brennan Louise A Brinton Michelle Brotzman H Bas Bueno-de-Mesquita Julie E Buring Mary Ann Butler Qiuyin Cai Geraldine Cancel-Tassin Federico Canzian Guangwen Cao Neil E Caporaso Alfredo Carrato Tania Carreon Angela Carta Gee-Chen Chang I-Shou Chang Jenny Chang-Claude Xu Che Chien-Jen Chen Chih-Yi Chen Chung-Hsing Chen Constance Chen Kuan-Yu Chen Yuh-Min Chen Anand P Chokkalingam Lisa W Chu Francoise Clavel-Chapelon Graham A Colditz Joanne S Colt David Conti Michael B Cook Victoria K Cortessis E David Crawford Olivier Cussenot Faith G Davis Immaculata De Vivo Xiang Deng Ti Ding Colin P Dinney Anna Luisa Di Stefano W Ryan Diver Eric J Duell Joanne W Elena Jin-Hu Fan Heather Spencer Feigelson Maria Feychting Jonine D Figueroa Adrienne M Flanagan Joseph F Fraumeni Neal D Freedman Brooke L Fridley Charles S Fuchs Manuela Gago-Dominguez Steven Gallinger Yu-Tang Gao Susan M Gapstur Montserrat Garcia-Closas Reina Garcia-Closas Julie M Gastier-Foster J Michael Gaziano Daniela S Gerhard Carol A Giffen Graham G Giles Elizabeth M Gillanders Edward L Giovannucci Michael Goggins Nalan Gokgoz Alisa M Goldstein Carlos Gonzalez Richard Gorlick Mark H Greene Myron Gross H Barton Grossman Robert Grubb Jian Gu Peng Guan Christopher A Haiman Goran Hallmans Susan E Hankinson Curtis C Harris Patricia Hartge Claudia Hattinger Richard B Hayes Qincheng He Lee Helman Brian E Henderson Roger Henriksson Judith Hoffman-Bolton Chancellor Hohensee Elizabeth A Holly Yun-Chul Hong Robert N Hoover H Dean Hosgood Chin-Fu Hsiao Ann W Hsing Chao Agnes Hsiung Nan Hu Wei Hu Zhibin Hu Ming-Shyan Huang David J Hunter Peter D Inskip Hidemi Ito Eric J Jacobs Kevin B Jacobs Mazda Jenab Bu-Tian Ji Christoffer Johansen Mattias Johansson Alison Johnson Rudolf Kaaks Ashish M Kamat Aruna Kamineni Margaret Karagas Chand Khanna Kay-Tee Khaw Christopher Kim In-Sam Kim Jin Hee Kim Yeul Hong Kim Young-Chul Kim Young Tae Kim Chang Hyun Kang Yoo Jin Jung Cari M Kitahara Alison P Klein Robert Klein Manolis Kogevinas Woon-Puay Koh Takashi Kohno Laurence N Kolonel Charles Kooperberg Christian P Kratz Vittorio Krogh Hideo Kunitoh Robert C Kurtz Nilgun Kurucu Qing Lan Mark Lathrop Ching C Lau Fernando Lecanda Kyoung-Mu Lee Maxwell P Lee Loic Le Marchand Seth P Lerner Donghui Li Linda M Liao Wei-Yen Lim Dongxin Lin Jie Lin Sara Lindstrom Martha S Linet Jolanta Lissowska Jianjun Liu Börje Ljungberg Josep Lloreta Daru Lu Jing Ma Nuria Malats Satu Mannisto Neyssa Marina Giuseppe Mastrangelo Keitaro Matsuo Katherine A McGlynn Roberta McKean-Cowdin Lorna H McNeill Robert R McWilliams Beatrice S Melin Paul S Meltzer James E Mensah Xiaoping Miao Dominique S Michaud Alison M Mondul Lee E Moore Kenneth Muir Shelley Niwa Sara H Olson Nick Orr Salvatore Panico Jae Yong Park Alpa V Patel Ana Patino-Garcia Sofia Pavanello Petra H M Peeters Beata Peplonska Ulrike Peters Gloria M Petersen Piero Picci Malcolm C Pike Stefano Porru Jennifer Prescott Xia Pu Mark P Purdue You-Lin Qiao Preetha Rajaraman Elio Riboli Harvey A Risch Rebecca J Rodabough Nathaniel Rothman Avima M Ruder Jeong-Seon Ryu Marc Sanson Alan Schned Fredrick R Schumacher Ann G Schwartz Kendra L Schwartz Molly Schwenn Katia Scotlandi Adeline Seow Consol Serra Massimo Serra Howard D Sesso Gianluca Severi Hongbing Shen Min Shen Sanjay Shete Kouya Shiraishi Xiao-Ou Shu Afshan Siddiq Luis Sierrasesumaga Sabina Sierri Alan Dart Loon Sihoe Debra T Silverman Matthias Simon Melissa C Southey Logan Spector Margaret Spitz Meir Stampfer Par Stattin Mariana C Stern Victoria L Stevens Rachael Z Stolzenberg-Solomon Daniel O Stram Sara S Strom Wu-Chou Su Malin Sund Sook Whan Sung Anthony Swerdlow Wen Tan Hideo Tanaka Wei Tang Ze-Zhang Tang Adonina Tardon Evelyn Tay Philip R Taylor Yao Tettey David M Thomas Roberto Tirabosco Anne Tjonneland Geoffrey S Tobias Jorge R Toro Ruth C Travis Dimitrios Trichopoulos Rebecca Troisi Ann Truelove Ying-Huang Tsai Margaret A Tucker Rosario Tumino David Van Den Berg Stephen K Van Den Eeden Roel Vermeulen Paolo Vineis Kala Visvanathan Ulla Vogel Chaoyu Wang Chengfeng Wang Junwen Wang Sophia S Wang Elisabete Weiderpass Stephanie J Weinstein Nicolas Wentzensen William Wheeler Emily White John K Wiencke Alicja Wolk Brian M Wolpin Maria Pik Wong Margaret Wrensch Chen Wu Tangchun Wu Xifeng Wu Yi-Long Wu Jay S Wunder Yong-Bing Xiang Jun Xu Hannah P Yang Pan-Chyr Yang Yasushi Yatabe Yuanqing Ye Edward D Yeboah Zhihua Yin Chen Ying Chong-Jen Yu Kai Yu Jian-Min Yuan Krista A Zanetti Anne Zeleniuch-Jacquotte Wei Zheng Baosen Zhou Lisa Mirabello Sharon A Savage Peter Kraft Stephen J Chanock Meredith Yeager Maria Terese Landi Jianxin Shi Nilanjan Chatterjee Laufey T Amundadottir

Hum Mol Genet 2014 Dec 15;23(24):6616-33. Epub 2014 Jul 15.

Division of Cancer Epidemiology and Genetics,

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http://kooperberg.fhcrc.org/papers/2014wang.pdf
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http://hmg.oxfordjournals.org/content/23/24/6616.full.pdf
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddu363
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http://dx.doi.org/10.1093/hmg/ddu363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240198PMC
December 2014

Targeting polo-like kinase 1 by NMS-P937 in osteosarcoma cell lines inhibits tumor cell growth and partially overcomes drug resistance.

Invest New Drugs 2014 Dec 7;32(6):1167-80. Epub 2014 Sep 7.

Laboratory of Experimental Oncology, Rizzoli Orthopaedic Institute, Via di Barbiano 1/10, 40136, Bologna, Italy.

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http://dx.doi.org/10.1007/s10637-014-0158-6DOI Listing
December 2014

Copy number alterations and neoplasia-specific mutations in MELK, PDCD1LG2, TLN1, and PAX5 at 9p in different neoplasias.

Genes Chromosomes Cancer 2014 Jul 24;53(7):579-88. Epub 2014 Mar 24.

Department of Pathology, Haartman Institute and HUSLAB, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

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http://doi.wiley.com/10.1002/gcc.22168
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http://dx.doi.org/10.1002/gcc.22168DOI Listing
July 2014

Modulation of the osteosarcoma expression phenotype by microRNAs.

PLoS One 2012 25;7(10):e48086. Epub 2012 Oct 25.

The EuroBoNet Network of Excellence on Bone Tumours, Department of Tumor Biology, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo University Hospital, Oslo, Norway.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048086PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485010PMC
May 2013

A small-molecule RGD-integrin antagonist inhibits cell adhesion, cell migration and induces anoikis in glioblastoma cells.

Int J Oncol 2013 Jan 20;42(1):83-92. Epub 2012 Nov 20.

Department of Developmental and Molecular Biology, Albert Einstein College of Medicine of Yeshiva University, Bronx, NY 10461, USA.

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http://dx.doi.org/10.3892/ijo.2012.1708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583633PMC
January 2013

Experimental design applied to the optimization of microwave-assisted DNA hydrolysis.

J Chromatogr A 2012 Aug 15;1249:8-16. Epub 2012 Jun 15.

Department of Drug Sciences, University of Pavia, viale Taramelli 12, 27100 Pavia, Italy.

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http://dx.doi.org/10.1016/j.chroma.2012.06.015DOI Listing
August 2012

Functional characterization of osteosarcoma cell lines provides representative models to study the human disease.

Lab Invest 2011 Aug 25;91(8):1195-205. Epub 2011 Apr 25.

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/labinvest.2011.72DOI Listing
August 2011

Stereoselective Pd-catalyzed synthesis of quaternary α-D-C-mannosyl-(S)-amino acids.

J Org Chem 2011 Jul 2;76(13):5247-57. Epub 2011 Jun 2.

Dipartimento di Chimica Farmaceutica, Università degli Studi di Pavia, viale Taramelli 12, 27100 Pavia, Italy.

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http://dx.doi.org/10.1021/jo2002962DOI Listing
July 2011

Array comparative genomic hybridization reveals frequent alterations of G1/S checkpoint genes in undifferentiated pleomorphic sarcoma of bone.

Genes Chromosomes Cancer 2011 May 19;50(5):291-306. Epub 2011 Jan 19.

Department of Pathology, Haartman Institute and HUSLAB, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

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http://doi.wiley.com/10.1002/gcc.20851
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http://dx.doi.org/10.1002/gcc.20851DOI Listing
May 2011

Emerging drugs for high-grade osteosarcoma.

Expert Opin Emerg Drugs 2010 Dec 9;15(4):615-34. Epub 2010 Aug 9.

Rizzoli Orthopaedic Institute, Pharmacogenomics and Pharmacogenetics Research Unit, Laboratory of Experimental Oncology, Via di Barbiano 1/10, 40136 Bologna, Italy.

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http://dx.doi.org/10.1517/14728214.2010.505603DOI Listing
December 2010

A combined high-resolution mass spectrometric and in silico approach for the characterisation of small ligands of beta2-microglobulin.

ChemMedChem 2010 Jul;5(7):1015-25

Dipartimento di Scienze Farmaceutiche Pietro Pratesi, Università degli Studi di Milano, Via Mangiagalli 25, Milan, Italy.

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http://dx.doi.org/10.1002/cmdc.201000082DOI Listing
July 2010

Frequent deletion of CDKN2A and recurrent coamplification of KIT, PDGFRA, and KDR in fibrosarcoma of bone--an array comparative genomic hybridization study.

Genes Chromosomes Cancer 2010 Feb;49(2):132-43

Department of Pathology, Haartman Institute and HUSLAB, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1002/gcc.20727DOI Listing
February 2010

Design, synthesis and SAR analysis of novel selective sigma1 ligands (Part 2).

Bioorg Med Chem 2010 Feb 21;18(3):1204-12. Epub 2009 Dec 21.

Department of Pharmaceutical Chemistry, University of Pavia, Viale Taramelli 12, 27100 Pavia, Italy.

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http://dx.doi.org/10.1016/j.bmc.2009.12.039DOI Listing
February 2010

Caveolins in the development and diseases of musculoskeletal system.

Cancer Lett 2009 Nov 3;284(2):113-21. Epub 2009 Apr 3.

Department of Musculoskeletal Oncology, Oncologic Research Laboratory, Servizio Sanitario Regionale Emilia-Romagna, Istituto Ortopedici Rizzoli, IRCCS, Via di Barbiano 1/10, 40136 Bologna, Italy.

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http://dx.doi.org/10.1016/j.canlet.2009.02.016DOI Listing
November 2009

Small molecule integrin antagonists in cancer therapy.

Mini Rev Med Chem 2009 Oct;9(12):1439-46

Dipartimento di Farmacologia Sperimentale ed Applicata, Università di Pavia, Italy.

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October 2009

LSAMP, a novel candidate tumor suppressor gene in human osteosarcomas, identified by array comparative genomic hybridization.

Genes Chromosomes Cancer 2009 Aug;48(8):679-93

Department of Tumor Biology, The Norwegian Radium Hospital, Rikshospitalet University Hospital, Oslo, Norway.

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http://doi.wiley.com/10.1002/gcc.20675
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http://dx.doi.org/10.1002/gcc.20675DOI Listing
August 2009

Overcoming resistance to conventional drugs in Ewing sarcoma and identification of molecular predictors of outcome.

J Clin Oncol 2009 May 23;27(13):2209-16. Epub 2009 Mar 23.

Laboratory of Oncologic Research, Orthopaedic Institute Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.

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http://dx.doi.org/10.1200/JCO.2008.19.2542DOI Listing
May 2009

Clinical impact of the methotrexate resistance-associated genes C-MYC and dihydrofolate reductase (DHFR) in high-grade osteosarcoma.

Ann Oncol 2008 Aug 2;19(8):1500-8. Epub 2008 Apr 2.

Laboratorio di Ricerca Oncologica, Istituti Ortopedici Rizzoli, Bologna, Italy.

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http://dx.doi.org/10.1093/annonc/mdn148DOI Listing
August 2008

Prognostic value of CCN3 in osteosarcoma.

Clin Cancer Res 2008 Feb;14(3):701-9

Laboratorio di Ricerca Oncologica and Laboratorio di Rigenerazione Tissutale Ossea, Istituti Ortopedici Rizzoli, Bologna, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0806DOI Listing
February 2008

Genomic imbalances associated with secondary acute leukemias in Hodgkin lymphoma.

Oncol Rep 2007 Dec;18(6):1427-34

Istituto di Ematologia e Oncologia Medica Lorenzo e Ariosto Seràgnoli, Università di Bologna - Medical School, 40138 Bologna, Italy.

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December 2007

Malignant fibrous histiocytoma of bone: analysis of genomic imbalances by comparative genomic hybridisation and C-MYC expression by immunohistochemistry.

Eur J Cancer 2006 May 19;42(8):1172-80. Epub 2006 Apr 19.

Department of Pathology, Haartman Institute and HUSLAB, University of Helsinki and Helsinki University Central Hospital, P.O. Box 21, FI-00014 Helsinki, Finland.

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http://dx.doi.org/10.1016/j.ejca.2006.01.035DOI Listing
May 2006

No correlation between methotrexate serum level and histologic response in the pre-operative treatment of extremity osteosarcoma.

Anticancer Drugs 2006 Apr;17(4):411-5

Chemotherapy Research of the Department of Musculoskeletal Oncology, Istituti Ortopedici Rizzoli, Bologna, Italy.

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http://dx.doi.org/10.1097/01.cad.0000203379.14738.d9DOI Listing
April 2006

Prognostic and therapeutic relevance of HER2 expression in osteosarcoma and Ewing's sarcoma.

Eur J Cancer 2005 Jun;41(9):1349-61

Laboratorio di Ricerca Oncologica, Istituti Ortopedici Rizzoli, Via di Barbiano 1/10, 40136 Bologna, Italy.

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http://dx.doi.org/10.1016/j.ejca.2005.03.015DOI Listing
June 2005

Gene amplifications in osteosarcoma-CGH microarray analysis.

Genes Chromosomes Cancer 2005 Feb;42(2):158-63

Departments of Pathology and Medical Genetics, Haartman Institute and HUSLAB, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland.

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http://doi.wiley.com/10.1002/gcc.20120
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http://dx.doi.org/10.1002/gcc.20120DOI Listing
February 2005

The use of autologous platelet gel to treat difficult-to-heal wounds: a pilot study.

Transfusion 2004 Jul;44(7):1013-8

Department of Haematology & Blood Transfusion Medicine, Ospedale Santi Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.

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http://dx.doi.org/10.1111/j.1537-2995.2004.03366.xDOI Listing
July 2004

Differentially expressed genes in multidrug resistant variants of U-2 OS human osteosarcoma cells.

Oncol Rep 2004 Jun;11(6):1257-63

Department of Clinical Laboratory Medicine, Shiga University of Medical Science, Tsukinowa-cho, Seta, Otsu, Shiga 520-2192, Japan.

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June 2004

Identification of markers of possible prognostic value in 57 giant cell tumors of bone.

Oncol Rep 2003 Mar-Apr;10(2):351-6

Laboratory of Oncologic Research, Rizzoli Orthopaedic Institute, I-40136 Bologna, Italy.

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July 2003

Value of P-glycoprotein and clinicopathologic factors as the basis for new treatment strategies in high-grade osteosarcoma of the extremities.

J Clin Oncol 2003 Feb;21(3):536-42

Laboratorio di Ricerca Oncologica, Sezione di Chemioterapia, Servizio di Anatomia Patologica, Va Divisione, and Unita' di Chirurgia Generale, Istituti Ortopedici Rizzoli, Bologna, Italy.

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http://dx.doi.org/10.1200/JCO.2003.03.144DOI Listing
February 2003

Preferential expression of RB1-inducible coiled-coil 1 in terminal differentiated musculoskeletal cells.

Am J Pathol 2002 Aug;161(2):359-64

Department of Clinical Laboratory Medicine, Shiga University of Medical Science, Otsu, Shiga, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1850752PMC
http://dx.doi.org/10.1016/S0002-9440(10)64190-9DOI Listing
August 2002