Massimo Filippi

Massimo Filippi

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Massimo Filippi

Massimo Filippi

Publications by authors named "Massimo Filippi"

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Longitudinal spinal cord atrophy in multiple sclerosis using the generalized boundary shift integral.

Ann Neurol 2019 Nov 22;86(5):704-713. Epub 2019 Aug 22.

Queen Square Multiple Sclerosis Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.25571DOI Listing
November 2019

Functional and structural plasticity following action observation training in multiple sclerosis.

Mult Scler 2019 Oct 7;25(11):1472-1487. Epub 2018 Aug 7.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518792771DOI Listing
October 2019

Northwestern Anagram Test-Italian (Nat-I) for primary progressive aphasia.

Cortex 2019 Oct 21;119:497-510. Epub 2019 Aug 21.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy; Neurology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cortex.2019.08.007DOI Listing
October 2019

Multiple sclerosis associated with pembrolizumab in a patient with non-small cell lung cancer.

J Neurol 2019 Oct 4. Epub 2019 Oct 4.

Neurology Unit, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

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http://link.springer.com/10.1007/s00415-019-09562-z
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http://dx.doi.org/10.1007/s00415-019-09562-zDOI Listing
October 2019

Clinically relevant cranio-caudal patterns of cervical cord atrophy evolution in MS.

Neurology 2019 Oct 14. Epub 2019 Oct 14.

From the Neuroimaging Research Unit (M.A.R., P.V., A.M., P.P., M.F.) and Neurology Unit (M.A.R., P.P., G.C., M.F.), Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy; Department of Neurology (C.G., C.Z.), Neurocenter of Southern Switzerland, Regional Hospital Lugano (EOC), Lugano; Faculty of Biomedical Sciences (C.G., C.Z.), Università della Svizzera Italiana, Lugano, Switzerland; Section of Neuroradiology and MRI Unit, Department of Radiology (A.R.), and Department of Neurology/Neuroimmunology (X.M.), Multiple Sclerosis Centre of Catalonia, Hospital Universitari Vall d'Hebron, Barcelona, Spain; NMR Research Unit (H.K., O.C.), Queen Square MS Centre, Department of Neuroinflammation, UCL Institute of Neurology, London; Nuffield Department of Clinical Neurosciences (L.M., J.P.), University of Oxford, UK; Department of Advanced Medical and Surgical Sciences, and 3T MRI Center, (A.G., A.B.), University of Campania "Luigi Vanvitelli," Naples, Italy; Department of Neurology (A.G., P.E.), Universitätsmedizin Mannheim, University of Heidelberg, Germany; Department of Radiology and Nuclear Medicine (C.L., B.B.) and Institute of Neuroradiology (C.L., B.B.), St. Josef Hospital, Ruhr-University Bochum, Germany; Department of Radiology and Nuclear Medicine (F.B., H.V.), MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, location VUmc, the Netherlands; Institutes of Neurology and Healthcare Engineering (F.B.), University College London, UK; and Vita-Salute San Raffaele University (P.P., G.C., M.F.), Milan, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000008466DOI Listing
October 2019

Application of advanced MRI techniques to monitor pharmacologic and rehabilitative treatment in multiple sclerosis: current status and future perspectives.

Expert Rev Neurother 2019 Sep 30;19(9):835-866. Epub 2018 Dec 30.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University , Milan , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14737175.2019.1
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http://dx.doi.org/10.1080/14737175.2019.1555038DOI Listing
September 2019

The "central vein sign" in patients with diagnostic "red flags" for multiple sclerosis: A prospective multicenter 3T study.

Mult Scler 2019 Sep 19:1352458519876031. Epub 2019 Sep 19.

Department of Neurology, Center of Clinical Neurosciences, Lausanne University Hospital, Lausanne, Switzerland.

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http://dx.doi.org/10.1177/1352458519876031DOI Listing
September 2019

Cognitive impairment and structural brain damage in multiple system atrophy-parkinsonian variant.

J Neurol 2019 Sep 26. Epub 2019 Sep 26.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Via Olgettina, 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s00415-019-09555-yDOI Listing
September 2019

Dynamic volumetric changes of hippocampal subfields in clinically isolated syndrome patients: A 2-year MRI study.

Mult Scler 2019 Aug 24;25(9):1232-1242. Epub 2018 Jul 24.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://journals.sagepub.com/doi/10.1177/1352458518787347
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http://dx.doi.org/10.1177/1352458518787347DOI Listing
August 2019

Multi-branch convolutional neural network for multiple sclerosis lesion segmentation.

Neuroimage 2019 08 3;196:1-15. Epub 2019 Apr 3.

Pattern Analysis and Computer Vision (PAVIS), Istituto Italiano di Tecnologia (IIT), Genoa, Italy; NeuroInformatics Laboratory, Fondazione Bruno Kessler, Trento, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2019.03.068DOI Listing
August 2019

Concurrence of NMOSD and ALS in a patient with hexanucleotide repeat expansions of C9orf72.

Amyotroph Lateral Scler Frontotemporal Degener 2019 Aug 22;20(5-6):449-452. Epub 2019 Apr 22.

a Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, IRCCS San Raffaele Scientific Institute , Vita-Salute San Raffaele University , Milan , Italy.

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https://www.tandfonline.com/doi/full/10.1080/21678421.2019.1
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http://dx.doi.org/10.1080/21678421.2019.1604761DOI Listing
August 2019

MRI quality control for the Italian Neuroimaging Network Initiative: moving towards big data in multiple sclerosis.

J Neurol 2019 Aug 17. Epub 2019 Aug 17.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Via Olgettina, 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s00415-019-09509-4DOI Listing
August 2019

Effects of Natalizumab and Fingolimod on Clinical, Cognitive, and Magnetic Resonance Imaging Measures in Multiple Sclerosis.

Neurotherapeutics 2019 Aug 26. Epub 2019 Aug 26.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele Scientific Institute, Via Olgettina, 60, Milan, 20132, Italy.

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http://dx.doi.org/10.1007/s13311-019-00781-wDOI Listing
August 2019

PET is necessary to make the next step forward in understanding MS pathophysiology - No.

Mult Scler 2019 Jul 27;25(8):1088-1090. Epub 2019 Feb 27.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518820238DOI Listing
July 2019

Brain MRI shows white matter sparing in Kennedy's disease and slow-progressing lower motor neuron disease.

Hum Brain Mapp 2019 Jul 28;40(10):3102-3112. Epub 2019 Mar 28.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1002/hbm.24583DOI Listing
July 2019

Axonal degeneration as substrate of fractional anisotropy abnormalities in multiple sclerosis cortex.

Brain 2019 Jul;142(7):1921-1937

Department of Anatomy and Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/brain/awz143DOI Listing
July 2019

Influence of CNS T2-focal lesions on cervical cord atrophy and disability in multiple sclerosis.

Mult Scler 2019 Jul 26:1352458519865989. Epub 2019 Jul 26.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy/Department of Neurology, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1177/1352458519865989DOI Listing
July 2019

Characterizing Rapid Fluctuations of Resting State Functional Connectivity in Demyelinating, Neurodegenerative, and Psychiatric Conditions: From Static to Time-Varying Analysis.

Front Neurosci 2019 10;13:618. Epub 2019 Jul 10.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.3389/fnins.2019.00618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636554PMC
July 2019

Cross-modal plasticity among sensory networks in neuromyelitis optica spectrum disorders.

Mult Scler 2019 Jun 17;25(7):968-979. Epub 2018 May 17.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518778008DOI Listing
June 2019

Cortical Lesions on 7-T MRI in Multiple Sclerosis: A Window into Pathogenetic Mechanisms?

Radiology 2019 Jun 9;291(3):750-751. Epub 2019 Apr 9.

From the Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina 60, 20132 Milan, Italy.

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http://dx.doi.org/10.1148/radiol.2019190398DOI Listing
June 2019

Classifying silent progression in relapsing-remitting MS.

Nat Rev Neurol 2019 Jun;15(6):315-316

Neuroimaging Research Unit and Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1038/s41582-019-0199-8DOI Listing
June 2019

Resting State Dynamic Functional Connectivity in Neurodegenerative Conditions: A Review of Magnetic Resonance Imaging Findings.

Front Neurosci 2019 20;13:657. Epub 2019 Jun 20.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.3389/fnins.2019.00657DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596427PMC
June 2019

Hippocampal-related memory network in multiple sclerosis: A structural connectivity analysis.

Mult Scler 2019 May 23;25(6):801-810. Epub 2018 Apr 23.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518771838DOI Listing
May 2019

Functional MRI in Atypical Parkinsonisms.

Int Rev Neurobiol 2018;142:149-173. Epub 2018 Oct 25.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00747742183010
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http://dx.doi.org/10.1016/bs.irn.2018.09.002DOI Listing
May 2019

Imaging the migrainous brain: the present and the future.

Neurol Sci 2019 May;40(Suppl 1):49-54

Department of Neurology, IRCCS Ospedale San Raffaele, Vita-salute University, Via Olgettina 48, 20100, Milan, Italy.

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http://dx.doi.org/10.1007/s10072-019-03851-1DOI Listing
May 2019

Crossed aphasia confirmed by fMRI in a case with nonfluent variant of primary progressive aphasia carrying a GRN mutation.

J Neurol 2019 May 29;266(5):1274-1279. Epub 2019 Mar 29.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina, 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s00415-019-09298-wDOI Listing
May 2019

Functional brain connectivity abnormalities and cognitive deficits in neuromyelitis optica spectrum disorder.

Mult Scler 2019 May 13:1352458519845109. Epub 2019 May 13.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, IRCCS, San Raffaele Scientific Institute, Milan, Italy/Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458519845109DOI Listing
May 2019

10Kin1day: A Bottom-Up Neuroimaging Initiative.

Authors:
Martijn P van den Heuvel Lianne H Scholtens Hannelore K van der Burgh Federica Agosta Clara Alloza Celso Arango Bonnie Auyeung Simon Baron-Cohen Silvia Basaia Manon J N L Benders Frauke Beyer Linda Booij Kees P J Braun Geraldo Busatto Filho Wiepke Cahn Dara M Cannon Tiffany M Chaim-Avancini Sandra S M Chan Eric Y H Chen Benedicto Crespo-Facorro Eveline A Crone Udo Dannlowski Sonja M C de Zwarte Bruno Dietsche Gary Donohoe Stefan Du Plessis Sarah Durston Covadonga M Díaz-Caneja Ana M Díaz-Zuluaga Robin Emsley Massimo Filippi Thomas Frodl Martin Gorges Beata Graff Dominik Grotegerd Dariusz Gąsecki Julie M Hall Laurena Holleran Rosemary Holt Helene J Hopman Andreas Jansen Joost Janssen Krzysztof Jodzio Lutz Jäncke Vasiliy G Kaleda Jan Kassubek Shahrzad Kharabian Masouleh Tilo Kircher Martijn G J C Koevoets Vladimir S Kostic Axel Krug Stephen M Lawrie Irina S Lebedeva Edwin H M Lee Tristram A Lett Simon J G Lewis Franziskus Liem Michael V Lombardo Carlos Lopez-Jaramillo Daniel S Margulies Sebastian Markett Paulo Marques Ignacio Martínez-Zalacaín Colm McDonald Andrew M McIntosh Genevieve McPhilemy Susanne L Meinert José M Menchón Christian Montag Pedro S Moreira Pedro Morgado David O Mothersill Susan Mérillat Hans-Peter Müller Leila Nabulsi Pablo Najt Krzysztof Narkiewicz Patrycja Naumczyk Bob Oranje Victor Ortiz-Garcia de la Foz Jiska S Peper Julian A Pineda Paul E Rasser Ronny Redlich Jonathan Repple Martin Reuter Pedro G P Rosa Amber N V Ruigrok Agnieszka Sabisz Ulrich Schall Soraya Seedat Mauricio H Serpa Stavros Skouras Carles Soriano-Mas Nuno Sousa Edyta Szurowska Alexander S Tomyshev Diana Tordesillas-Gutierrez Sofie L Valk Leonard H van den Berg Theo G M van Erp Neeltje E M van Haren Judith M C van Leeuwen Arno Villringer Christiaan H Vinkers Christian Vollmar Lea Waller Henrik Walter Heather C Whalley Marta Witkowska A Veronica Witte Marcus V Zanetti Rui Zhang Siemon C de Lange

Front Neurol 2019 9;10:425. Epub 2019 May 9.

Connectome Lab, CTG, CNCR, VU Amsterdam, Amsterdam, Netherlands.

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https://www.frontiersin.org/article/10.3389/fneur.2019.00425
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http://dx.doi.org/10.3389/fneur.2019.00425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524614PMC
May 2019

Brain mapping in multiple sclerosis: Lessons learned about the human brain.

Neuroimage 2019 04 14;190:32-45. Epub 2017 Sep 14.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1016/j.neuroimage.2017.09.021DOI Listing
April 2019

Effect of HLA-DRB1 alleles and genetic variants on the development of neutralizing antibodies to interferon beta in the BEYOND and BENEFIT trials.

Mult Scler 2019 04 9;25(4):565-573. Epub 2018 Mar 9.

Department of Neurology, Klinikum rechts der Isar, Technische Universität München, München, Germany/German Competence Network Multiple Sclerosis (KKNMS), München, Germany/Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

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http://dx.doi.org/10.1177/1352458518763089DOI Listing
April 2019

Functional MRI in Idiopathic Parkinson's Disease.

Int Rev Neurobiol 2018 24;141:439-467. Epub 2018 Aug 24.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1016/bs.irn.2018.08.005DOI Listing
April 2019

Added value of multimodal MRI to the clinical diagnosis of primary progressive aphasia variants.

Cortex 2019 Apr 8;113:58-66. Epub 2018 Dec 8.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cortex.2018.11.025DOI Listing
April 2019

Dynamic gray matter volume changes in pediatric multiple sclerosis: A 3.5 year MRI study.

Neurology 2019 Apr 13;92(15):e1709-e1723. Epub 2019 Mar 13.

From the Neuroimaging Research Unit (E.D.M., A.M., M.F., M.A.R.) and Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience (E.D.M., L.M., M.F., M.A.R.), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan; Multiple Sclerosis Center (A.G.), Ospedale di Gallarate; Pediatric Neurology Unit (P.V.), V. Buzzi Children's Hospital, Milan; and Biomedical and Clinical Science Department (P.V.), University of Milan, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000007267DOI Listing
April 2019

Cognitive reserve, cognition, and regional brain damage in MS: A 2 -year longitudinal study.

Mult Scler 2019 03 5;25(3):372-381. Epub 2018 Jan 5.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458517750767DOI Listing
March 2019

Brain and cord imaging features in neuromyelitis optica spectrum disorders.

Ann Neurol 2019 Mar 28;85(3):371-384. Epub 2019 Jan 28.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://doi.wiley.com/10.1002/ana.25411
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http://dx.doi.org/10.1002/ana.25411DOI Listing
March 2019

Reduced dynamics of functional connectivity and cognitive impairment in multiple sclerosis.

Mult Scler 2019 Mar 19:1352458519837707. Epub 2019 Mar 19.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458519837707DOI Listing
March 2019

Two-year dynamic functional network connectivity in clinically isolated syndrome.

Mult Scler 2019 Mar 19:1352458519837704. Epub 2019 Mar 19.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458519837704DOI Listing
March 2019

White Matter Microstructure Breakdown in the Motor Neuron Disease Spectrum: Recent Advances Using Diffusion Magnetic Resonance Imaging.

Front Neurol 2019 5;10:193. Epub 2019 Mar 5.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.3389/fneur.2019.00193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413536PMC
March 2019

Imaging patterns of gray and white matter abnormalities associated with PASAT and SDMT performance in relapsing-remitting multiple sclerosis.

Mult Scler 2019 02 27;25(2):204-216. Epub 2017 Nov 27.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458517743091DOI Listing
February 2019

Targeting progression in multiple sclerosis - an update.

Nat Rev Neurol 2019 Feb;15(2):62-64

Neuroimaging Research Unit and Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, Scientific Institute and University Hospital San Raffaele, Milan, Italy.

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http://dx.doi.org/10.1038/s41582-018-0127-3DOI Listing
February 2019

Association between pathological and MRI findings in multiple sclerosis.

Lancet Neurol 2019 Feb;18(2):198-210

Neuroimaging Research Unit and Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1016/S1474-4422(18)30451-4DOI Listing
February 2019

Cross-sectional study of smoking exposure: no differential effect on OCT metrics in a cohort of MS patients.

Mult Scler J Exp Transl Clin 2019 Jan-Mar;5(1):2055217319828400. Epub 2019 Feb 25.

Ann Romney Center for Neurologic Disease, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1177/2055217319828400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390224PMC
February 2019

Resting-state Functional MRI in Parkinsonian Syndromes.

Mov Disord Clin Pract 2019 Feb 8;6(2):104-117. Epub 2019 Feb 8.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute Vita-Salute San Raffaele University Milan Italy.

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http://dx.doi.org/10.1002/mdc3.12730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384182PMC
February 2019

Functional and structural brain networks in posterior cortical atrophy: A two-centre multiparametric MRI study.

Neuroimage Clin 2018 12;19:901-910. Epub 2018 Jun 12.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, via Olgettina 60, 20132 Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, via Olgettina 60, 20132 Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2018.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019262PMC
January 2019

Unraveling treatment response in multiple sclerosis: A clinical and MRI challenge.

Neurology 2019 01 26;92(4):180-192. Epub 2018 Dec 26.

From the Department of Neurosciences (C.G., L.P.), San Camillo-Forlanini Hospital, Rome, Italy; Centre d'Esclerosi Multiple de Catalunya (Cemcat), Department of Neurology/Neuroimmunology (M.T., J.R., J.S.-G., X.M.), and Magnetic Resonance Unit, Department of Radiology (A.R.), Hospital Universitari Vall d'Hebron, Universitat Autonoma de Barcelona, Spain; Biostatistics Unit (M.P.S.), Department of Health Sciences, University of Genoa; Neuroimaging Research Unit (M.F., M.A.R.), Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Nuffield Department of Clinical Neurosciences (J.P.), West Wing, John Radcliffe Hospital, Oxford; Institutes of Neurology & Healthcare Engineering (O.C., F.B.), University College London (O.C.), UK; Amsterdam Neuroscience and Department of Radiology and Nuclear Medicine (F.B., H.V.), VU University Medical Center, Amsterdam, the Netherlands; Department of Neurology (J.L.F.), Rigshospitalet Glostrup and University of Copenhagen, Denmark; Neuroradiological Academic Unit (T.A.Y.), Institute of Neurology, London, UK; Department of Neurology (C.E.), Medical University of Graz, Austria; Neurologic Clinic and Policlinic, Department of Medicine (L.K.), Clinical Research, Biomedicine and Biomedical Engineering, University Hospital Basel, University of Basel, Switzerland; Department of Neurology and Psychiatry (C.P.), Sapienza University, Rome; and Neurology and Neurometabolic Unit, Department of Neurological and Behavioral Sciences (N.D.S.), University of Siena, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000006810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345120PMC
January 2019

Structural connectivity in multiple sclerosis and modeling of disconnection.

Mult Scler 2019 Jan 9:1352458518820759. Epub 2019 Jan 9.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518820759DOI Listing
January 2019

Imaging correlates of hand motor performance in multiple sclerosis: A multiparametric structural and functional MRI study.

Mult Scler 2019 Jan 18:1352458518822145. Epub 2019 Jan 18.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/ Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1177/1352458518822145DOI Listing
January 2019

Can action observation modulate balance performance in healthy subjects?

Arch Physiother 2019 22;9. Epub 2019 Jan 22.

1Laboratory of Movement Analysis, San Raffaele Scientific Institute, via Olgettina 58, 20132 Milan, Italy.

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http://dx.doi.org/10.1186/s40945-018-0053-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341526PMC
January 2019

Automated classification of Alzheimer's disease and mild cognitive impairment using a single MRI and deep neural networks.

Neuroimage Clin 2019 18;21:101645. Epub 2018 Dec 18.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2018.101645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413333PMC
December 2018

Multiple sclerosis.

Nat Rev Dis Primers 2018 11 8;4(1):43. Epub 2018 Nov 8.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://www.nature.com/articles/s41572-018-0041-4
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http://dx.doi.org/10.1038/s41572-018-0041-4DOI Listing
November 2018

Author Correction: Multiple sclerosis.

Nat Rev Dis Primers 2018 Nov 22;4(1):49. Epub 2018 Nov 22.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1038/s41572-018-0050-3DOI Listing
November 2018

The hippocampus in multiple sclerosis.

Lancet Neurol 2018 10 18;17(10):918-926. Epub 2018 Sep 18.

Neuroimaging Research Unit and Department of Neurology, Institute of Experimental Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30309-0DOI Listing
October 2018

Brain motor functional changes after somatosensory discrimination training.

Brain Imaging Behav 2018 Aug;12(4):1011-1021

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina, 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1007/s11682-017-9763-2DOI Listing
August 2018

Measurement of Whole-Brain and Gray Matter Atrophy in Multiple Sclerosis: Assessment with MR Imaging.

Radiology 2018 08 1;288(2):554-564. Epub 2018 May 1.

From the Neuroimaging Research Unit (L.S., M.A.R., E.P., M.F.) and Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience (M.A.R., M.F.), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina 60, 20132 Milan, Italy; Department of Research and Development, Icometrix, Leuven, Belgium (W.V.H., D. Sima, D. Smeets); Xinapse Systems, Colchester, England (M.A.H.); Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy (N.D.S.); Section of Neuroradiology, Department of Radiology, Hospital Universitari Vall d'Hebron, Barcelona, Spain (A.R.); Unit of Clinical Neuroimmunology, CEM-Cat, Hospital Universitari Vall d'Hebron, Barcelona, Spain (J.S.G.); and Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, England (J.P.).

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http://dx.doi.org/10.1148/radiol.2018172468DOI Listing
August 2018

MRI of non-Alzheimer's dementia: current and emerging knowledge.

Curr Opin Neurol 2018 08;31(4):405-414

Neuroimaging Research Unit.

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http://dx.doi.org/10.1097/WCO.0000000000000571DOI Listing
August 2018

Recent advances in headache neuroimaging.

Curr Opin Neurol 2018 08;31(4):379-385

Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1097/WCO.0000000000000573DOI Listing
August 2018

MRI in multiple sclerosis: what is changing?

Curr Opin Neurol 2018 08;31(4):386-395

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1097/WCO.0000000000000572DOI Listing
August 2018

Are there two different forms of functional dystonia? A multimodal brain structural MRI study.

Mol Psychiatry 2018 Aug 17. Epub 2018 Aug 17.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1038/s41380-018-0222-2DOI Listing
August 2018

Tracking brain damage in progressive supranuclear palsy: a longitudinal MRI study.

J Neurol Neurosurg Psychiatry 2018 07 18;89(7):696-701. Epub 2018 Jan 18.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1136/jnnp-2017-317443DOI Listing
July 2018

Cervical Cord T1-weighted Hypointense Lesions at MR Imaging in Multiple Sclerosis: Relationship to Cord Atrophy and Disability.

Radiology 2018 Jul 17;288(1):234-244. Epub 2018 Apr 17.

From the Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience (P.V., M.A., P.P., R.M., M.F., M.A.R.), Department of Neurology (P.P., R.M., G.C., M.F., M.A.R.), and Department of Neuroradiology (A.F.), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina 60, 20132 Milan, Italy.

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http://dx.doi.org/10.1148/radiol.2018172311DOI Listing
July 2018

Gray matter volume modifications in migraine: A cross-sectional and longitudinal study.

Neurology 2018 07 20;91(3):e280-e292. Epub 2018 Jun 20.

From the Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience (R.M., M.A.R., E.P., M.F.) and Departments of Neurology (R.M., M.A.R., B.C., M.F.) and Neuroradiology (A.F.), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; and NIHR-Wellcome Trust King's Clinical Research Facility (P.J.G.), King's College London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000005819DOI Listing
July 2018

Cardiovascular disease and brain health: Focus on white matter hyperintensities.

Int J Cardiol Heart Vasc 2018 Jun 14;19:63-69. Epub 2018 May 14.

Cardiothoracic and Vascular Department, San Raffaele Hospital, Milan, Italy.

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http://dx.doi.org/10.1016/j.ijcha.2018.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016077PMC
June 2018

Neuroimaging in amyotrophic lateral sclerosis: current and emerging uses.

Expert Rev Neurother 2018 05 15;18(5):395-406. Epub 2018 Apr 15.

a Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience , San Raffaele Scientific Institute, Vita-Salute San Raffaele University , Milan , Italy.

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http://dx.doi.org/10.1080/14737175.2018.1463160DOI Listing
May 2018

Changes in functional and structural brain connectome along the Alzheimer's disease continuum.

Mol Psychiatry 2018 May 9. Epub 2018 May 9.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1038/s41380-018-0067-8DOI Listing
May 2018

Progression of white matter damage in progressive supranuclear palsy with predominant parkinsonism.

Parkinsonism Relat Disord 2018 04 4;49:95-99. Epub 2018 Jan 4.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2018.01.001DOI Listing
April 2018

Prediction of a multiple sclerosis diagnosis in patients with clinically isolated syndrome using the 2016 MAGNIMS and 2010 McDonald criteria: a retrospective study.

Lancet Neurol 2018 02 21;17(2):133-142. Epub 2017 Dec 21.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1016/S1474-4422(17)30469-6DOI Listing
February 2018

Cognition in multiple sclerosis: State of the field and priorities for the future.

Neurology 2018 02 17;90(6):278-288. Epub 2018 Jan 17.

From the Department of Neurology & Corinne Goldsmith Dickinson Center for Multiple Sclerosis (J.F.S., M.I.), Icahn School of Medicine at Mount Sinai, New York; Department of Neurology (R.B.), School of Medicine and Biomedical Sciences, University of Buffalo, State University of New York (SUNY); Department of Neurology (C.E.), Medical University of Graz, Austria; Department of Neurology & Neuroimaging Research Unit, Division of Neuroscience (M.F., M.A.R.), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Anatomy and Neurosciences (J.J.G., H.H.), VU University Medical Center, Amsterdam Neuroscience, VUmc MS Center Amsterdam, the Netherlands; Masku Neurological Rehabilitation Centre (P.H.), Masku, Finland; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, and Mother-Child Health (M.I.), University of Genoa, Italy; Department of Neurology & Columbia University Multiple Sclerosis Clinical Care and Research Center (V.M.L.), Columbia University Medical Center, New York, NY; Department of Neurology and Rehabilitation (E.M.R.-O.), Tampere University Hospital, Finland; and Schey Center for Cognitive Neuroimaging, Neurological Institute (S.R.), Cleveland Clinic, OH.

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http://dx.doi.org/10.1212/WNL.0000000000004977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818015PMC
February 2018

Unraveling ALS due to mutation through the combination of brain and cervical cord MRI.

Neurology 2018 02 24;90(8):e707-e716. Epub 2018 Jan 24.

From the Neuroimaging Research Unit (F.A., E.G.S., E.P., P.V., M.F.) and Department of Neurology (M.F.), Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; and Clinic of Neurology (I.V.M., Z.S., B.S.-D., M.J., D.L., V.S.K.), Faculty of Medicine, University of Belgrade, Serbia.

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http://dx.doi.org/10.1212/WNL.0000000000005002DOI Listing
February 2018

Effects of pharmacological and nonpharmacological treatments on brain functional magnetic resonance imaging in Alzheimer's disease and mild cognitive impairment: a critical review.

Alzheimers Res Ther 2018 02 20;10(1):21. Epub 2018 Feb 20.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina, 60, 20132, Milan, Italy.

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http://dx.doi.org/10.1186/s13195-018-0347-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819240PMC
February 2018

Mirror therapy for an adult with central post-stroke pain: a case report.

Arch Physiother 2018 23;8. Epub 2018 Feb 23.

4Humanitas Clinical and Research Center, Humanitas University, Rozzano, Italy.

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http://dx.doi.org/10.1186/s40945-018-0047-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824546PMC
February 2018

Necrotic-hemorrhagic myelitis: A rare malignant variant of parainfectious acute disseminated encephalomyelitis in childhood.

J Neurol Sci 2018 01 23;384:58-60. Epub 2017 Nov 23.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2017.11.032DOI Listing
January 2018

Structural connectivity-defined thalamic subregions have different functional connectivity abnormalities in multiple sclerosis patients: Implications for clinical correlations.

Hum Brain Mapp 2017 12 7;38(12):6005-6018. Epub 2017 Sep 7.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://doi.wiley.com/10.1002/hbm.23805
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http://dx.doi.org/10.1002/hbm.23805DOI Listing
December 2017

Long-term disability progression in primary progressive multiple sclerosis: a 15-year study.

Brain 2017 Nov;140(11):2814-2819

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1093/brain/awx250DOI Listing
November 2017

Brain network connectivity differs in early-onset neurodegenerative dementia.

Neurology 2017 Oct 27;89(17):1764-1772. Epub 2017 Sep 27.

From the Neuroimaging Research Unit (M. Filippi, S.B., E.C., F.I., A.M., F.C., F.A.), Department of Neurology (M. Filippi, G.M., M. Falautano, G.C.), Institute of Experimental Neurology, Division of Neuroscience, and Department of Neuroradiology and CERMAC (A.F.), Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000004577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664301PMC
October 2017

MRI substrates of sustained attention system and cognitive impairment in pediatric MS patients.

Neurology 2017 Sep 18;89(12):1265-1273. Epub 2017 Aug 18.

From the Neuroimaging Research Unit (E.D.M., E.P., M.F., M.A.R.) and Department of Neurology (E.D.M., L.M., A. Fiorino, G.C., M.F., M.A.R.), Institute of Experimental Neurology, Division of Neuroscience, and Department of Neuroradiology (A. Falini), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan; Multiple Sclerosis Center (A.G., L.P.), Ospedale di Gallarate; Department of Child Neurology and Psychiatry (P.V., M.C.P.), C. Mondino National Neurological Institute, Brain and Behaviour Department, University of Pavia; Multiple Sclerosis Center (R.C.), Spedali Civili of Brescia; and Department NEUROFARBA (M.P.A.), Section Neurosciences, University of Florence, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000004388DOI Listing
September 2017

The Role of T1-Weighted Derived Measures of Neurodegeneration for Assessing Disability Progression in Multiple Sclerosis.

Front Neurol 2017 4;8:433. Epub 2017 Sep 4.

Neuroimaging Research Unit, Institute of Experimental Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.3389/fneur.2017.00433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591328PMC
September 2017