Massimo F Martelli

Massimo F Martelli

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Massimo F Martelli

Massimo F Martelli

Publications by authors named "Massimo F Martelli"

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Clinical-Grade-Expanded Regulatory T Cells Prevent Graft-versus-Host Disease While Allowing a Powerful T Cell-Dependent Graft-versus-Leukemia Effect in Murine Models.

Biol Blood Marrow Transplant 2017 Nov 17;23(11):1847-1851. Epub 2017 Jul 17.

Department of Hematology, Transfusion Medicine and Biotechnologies, Ospedale Civile, Pescara, Italy; Department of Medicine and Aging Sciences, University of Chieti-Pescara, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2017.07.009DOI Listing
November 2017

Haploidentical transplants using ex vivo T-cell depletion.

Semin Hematol 2016 10 25;53(4):252-256. Epub 2016 Jul 25.

Hematology and Bone Marrow Transplantation Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy.

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http://dx.doi.org/10.1053/j.seminhematol.2016.07.001DOI Listing
October 2016

Differences in Aspergillus-specific immune recovery between T-cell-replete and T-cell-depleted hematopoietic transplants.

Eur J Haematol 2015 Dec 16;95(6):551-7. Epub 2015 Mar 16.

Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.

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http://dx.doi.org/10.1111/ejh.12531DOI Listing
December 2015

"Designed" grafts for HLA-haploidentical stem cell transplantation.

Blood 2014 Feb 20;123(7):967-73. Epub 2013 Dec 20.

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy;

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http://dx.doi.org/10.1182/blood-2013-10-531764DOI Listing
February 2014

Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction.

Eur J Immunol 2013 Jan 5;43(1):182-7. Epub 2012 Dec 5.

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1002/eji.201242643DOI Listing
January 2013

Mutational landscape of AML with normal cytogenetics: biological and clinical implications.

Blood Rev 2013 Jan 20;27(1):13-22. Epub 2012 Dec 20.

Institute of Hematology, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1016/j.blre.2012.11.001DOI Listing
January 2013

Haploidentical hematopoietic stem cell transplantation with a megadose T-cell-depleted graft: harnessing natural and adaptive immunity.

Semin Oncol 2012 Dec;39(6):643-52

Section of Hematology and BMT Unit, University of Parma, Parma, Italy.

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http://dx.doi.org/10.1053/j.seminoncol.2012.09.002DOI Listing
December 2012

T regulatory cell separation for clinical application.

Transfus Apher Sci 2012 Oct 12;47(2):213-6. Epub 2012 Jul 12.

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy.

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http://dx.doi.org/10.1016/j.transci.2012.06.007DOI Listing
October 2012

High-dose thiotepa, etoposide and carboplatin as conditioning regimen for autologous stem cell transplantation in patients with high-risk non-Hodgkin lymphoma.

Clin Exp Med 2012 Sep 18;12(3):165-71. Epub 2011 Sep 18.

Department of Clinical and Experimental Medicine, Section of Hematology and Clinical Immunology, University of Perugia Medical School, Perugia, Italy.

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http://dx.doi.org/10.1007/s10238-011-0157-2DOI Listing
September 2012

High-dose thiotepa, etoposide and carboplatin as conditioning regimen for autologous stem cell transplantation in patients with high-risk Hodgkin's lymphoma.

Hematology 2012 Jan;17(1):23-7

Department of Clinical and Experimental Medicine, Section of Hematology and Clinical Immunology, University of Perugia Medical School, I-06100 Perugia, Italy.

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http://dx.doi.org/10.1179/102453312X13221316477534DOI Listing
January 2012

Haploidentical hematopoietic transplantation: current status and future perspectives.

Blood 2011 Dec 14;118(23):6006-17. Epub 2011 Sep 14.

Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2011-07-33
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http://dx.doi.org/10.1182/blood-2011-07-338822DOI Listing
December 2011

The importance of bone marrow transplantation for patients who do not have a matched sibling donor.

Best Pract Res Clin Haematol 2011 Sep 29;24(3):323-4. Epub 2011 Jul 29.

Department of Immunology, Weizmann Institute of Science, Rehovot, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S15216926110006
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http://dx.doi.org/10.1016/j.beha.2011.06.002DOI Listing
September 2011

Immunoselection and clinical use of T regulatory cells in HLA-haploidentical stem cell transplantation.

Best Pract Res Clin Haematol 2011 Sep 29;24(3):459-66. Epub 2011 Jun 29.

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy.

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http://dx.doi.org/10.1016/j.beha.2011.05.005DOI Listing
September 2011

A NUP98-positive acute myeloid leukemia with a t(11;12)(p15;q13) without HOXC cluster gene involvement.

Cancer Genet Cytogenet 2009 Sep;193(2):109-11

Hematology and Bone Marrow Transplantation Unit, University of Perugia, Ematologia e Trapianto di Midollo Osseo, Ospedale S.M. della Misericordia, (Padiglione B, piano -2), S. Andrea delle Fratte, 06156 Perugia, Italy.

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http://dx.doi.org/10.1016/j.cancergencyto.2009.04.015DOI Listing
September 2009

Clinical impact of natural killer cell reconstitution after allogeneic hematopoietic transplantation.

Semin Immunopathol 2008 Dec 11;30(4):489-503. Epub 2008 Nov 11.

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Ospedale Santa Maria della Misericordia, Perugia, Italy.

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http://dx.doi.org/10.1007/s00281-008-0136-1DOI Listing
December 2008

t(3;11)(q12;p15)/NUP98-LOC348801 fusion transcript in acute myeloid leukemia.

Haematologica 2008 Sep 4;93(9):1398-401. Epub 2008 Jul 4.

IbiT Foundation, Fondazione IRCCS Biotecnologie nel Trapianto, Hematology, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.3324/haematol.12945DOI Listing
September 2008

The haploidentical option for high-risk haematological malignancies.

Blood Cells Mol Dis 2008 Jan-Feb;40(1):8-12. Epub 2007 Oct 1.

Department of Hematology, University of Perugia, Italy.

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http://dx.doi.org/10.1016/j.bcmd.2007.07.004DOI Listing
February 2008

Large-scale generation of human allodepleted anti-3rd party lymphocytes.

Blood Cells Mol Dis 2008 Jan-Feb;40(1):106-12. Epub 2007 Nov 1.

Department of Clinical and Experimental Medicine, IRCCS Foundation on Transplantation Biotechnologies, University of Perugia, Italy.

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http://dx.doi.org/10.1016/j.bcmd.2007.07.014DOI Listing
February 2008

NK cell alloreactivity and allogeneic hematopoietic stem cell transplantation.

Blood Cells Mol Dis 2008 Jan-Feb;40(1):84-90. Epub 2007 Oct 26.

Department of Clinical and Experimental Medicine, IRCCS Foundation on Transplantation Biotechnologies, University of Perugia, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S107997960700143
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http://dx.doi.org/10.1016/j.bcmd.2007.06.029DOI Listing
February 2008

Photodynamic purging of alloreactive T cells for adoptive immunotherapy after haploidentical stem cell transplantation.

Blood Cells Mol Dis 2008 Jan-Feb;40(1):76-83. Epub 2007 Nov 5.

Department of Clinical and Experimental Medicine, IRCCS Foundation on Transplantation Biotechnologies, University of Perugia, Via Brunamonti 51, 06123, Italy.

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http://dx.doi.org/10.1016/j.bcmd.2007.06.022DOI Listing
February 2008

From 'megadose' haploidentical hematopoietic stem cell transplants in acute leukemia to tolerance induction in organ transplantation.

Blood Cells Mol Dis 2008 Jan-Feb;40(1):1-7. Epub 2007 Nov 5.

Weizmann Institute of Science, Department of Immunology, POB 26, Rehovot 76100, Israel.

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http://dx.doi.org/10.1016/j.bcmd.2007.06.030DOI Listing
February 2008

Molecular cytogenetic findings in a four-way t(1;12;5;12)(p36;p13;q33;q24) underlying the ETV6-PDGFRB fusion gene in chronic myelomonocytic leukemia.

Cancer Genet Cytogenet 2007 Jul;176(1):67-71

Department of Hematology, University of Perugia, IBiT Foundation (Fondazione IRCCS Biotecnologie nel Trapianto), via Brunamonti 51, 06122 Perugia, Italy.

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http://dx.doi.org/10.1016/j.cancergencyto.2007.03.004DOI Listing
July 2007

Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML): biologic and clinical features.

Blood 2007 Feb 28;109(3):874-85. Epub 2006 Sep 28.

Institute of Hematology, University of Perugia, Italy.

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http://dx.doi.org/10.1182/blood-2006-07-012252DOI Listing
February 2007

Hematopoietic stem cell transplantation from alternative donors for high-risk acute leukemia: the haploidentical option.

Curr Stem Cell Res Ther 2007 Jan;2(1):105-12

Hematopoietic Stem Cell Transplant Unit, Section of Hematology and Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Perugia 06100, Italy.

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January 2007

Chronic lymphocytic leukaemia Is terminal del(14)(q24) a new marker for prognostic stratification?

Leuk Res 2006 Dec 2;30(12):1569-72. Epub 2006 May 2.

Hematology and Bone Marrow Transplantation Unit, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1016/j.leukres.2006.03.019DOI Listing
December 2006

Allogeneic hematopoietic transplantation and natural killer cell recognition of missing self.

Immunol Rev 2006 Dec;214:202-18

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Italy.

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http://dx.doi.org/10.1111/j.1600-065X.2006.00455.xDOI Listing
December 2006

Interleukin-7-engineered mesenchymal cells: in vitro effects on naive T-cell population.

Biol Blood Marrow Transplant 2006 Dec;12(12):1250-60

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, Perugia University, Perugia, Italy.

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http://dx.doi.org/10.1016/j.bbmt.2006.09.001DOI Listing
December 2006

Natural killer cell recognition of missing self and haploidentical hematopoietic transplantation.

Semin Cancer Biol 2006 Oct 8;16(5):404-11. Epub 2006 Jul 8.

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce, Via Brunamonti 51, Perugia, Italy.

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http://dx.doi.org/10.1016/j.semcancer.2006.07.007DOI Listing
October 2006

Nucleophosmin gene mutations are predictors of favorable prognosis in acute myelogenous leukemia with a normal karyotype.

Blood 2005 Dec 2;106(12):3733-9. Epub 2005 Aug 2.

Department of Internal Medicine III, University Hospital Grosshadern, Ludwig Maximilian's University, Munich, Germany.

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http://dx.doi.org/10.1182/blood-2005-06-2248DOI Listing
December 2005

Transferring functional immune responses to pathogens after haploidentical hematopoietic transplantation.

Blood 2005 Dec 25;106(13):4397-406. Epub 2005 Aug 25.

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce, Via Brunamonti 51-06122 Perugia, Italy.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2005-05-17
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http://dx.doi.org/10.1182/blood-2005-05-1775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895249PMC
December 2005

Natural killer cell alloreactivity for leukemia therapy.

J Immunother 2005 May-Jun;28(3):175-82

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, 06122 Perugia, Italy.

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October 2005

Nucleophosmin mutations in childhood acute myelogenous leukemia with normal karyotype.

Blood 2005 Aug 3;106(4):1419-22. Epub 2005 May 3.

Centro Ricerca Tettamanti, Clinica Pediatrica University of Milano-Bicocca, Ospedale San Gerardo, 20052 Monza, Italy.

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http://dx.doi.org/10.1182/blood-2005-03-0899DOI Listing
August 2005

The impact of donor natural killer cell alloreactivity on allogeneic hematopoietic transplantation.

Transpl Immunol 2005 Aug;14(3-4):203-6

Division of Haematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Italy.

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http://dx.doi.org/10.1016/j.trim.2005.03.008DOI Listing
August 2005

Crossing the HLA barriers.

Blood Cells Mol Dis 2004 Nov-Dec;33(3):206-10

Department of Immunology, The Weizmann Institute of Science, 76100 Rehovot, Israel.

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http://linkinghub.elsevier.com/retrieve/pii/S107997960400162
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http://dx.doi.org/10.1016/j.bcmd.2004.08.004DOI Listing
April 2005

Alloreactive natural killer cells in mismatched hematopoietic stem cell transplantation.

Blood Cells Mol Dis 2004 Nov-Dec;33(3):216-21

Department of Clinical and Experimental Medicine, Haematology and Clinical Immunology, University of Perugia, Italy.

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http://dx.doi.org/10.1016/j.bcmd.2004.08.005DOI Listing
April 2005

Hematopoietic stem cell transplantation from alternative sources in adults with high-risk acute leukemia.

Blood Cells Mol Dis 2004 Nov-Dec;33(3):294-302

Department of Hematology, University of Perugia, Perugia, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S107997960400178
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http://dx.doi.org/10.1016/j.bcmd.2004.08.021DOI Listing
April 2005

Fourth International Workshop on Haploidentical Transplants, Naples, Italy, July 8-10, 2004.

Blood Cells Mol Dis 2004 Nov-Dec;33(3):159-75

Department of Clinical and Experimental Medicine, University of Perugia, Italy.

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April 2005

Exploitation of alloreactive NK cells in adoptive immunotherapy of cancer.

Curr Opin Immunol 2005 Apr;17(2):211-7

Division of Haematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce, 06122 Perugia, Italy.

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http://dx.doi.org/10.1016/j.coi.2005.01.007DOI Listing
April 2005

Natural killer cell alloreactivity in haploidentical hematopoietic stem cell transplantation.

Int J Hematol 2005 Jan;81(1):13-7

Division of Haematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

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January 2005

Cryptic insertion producing two NUP98/NSD1 chimeric transcripts in adult refractory anemia with an excess of blasts.

Genes Chromosomes Cancer 2004 Dec;41(4):395-9

Hematology and Bone Marrow Transplantation Unit, University of Perugia, 06123 Perugia, Italy.

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http://dx.doi.org/10.1002/gcc.20103DOI Listing
December 2004

Melphalan versus melphalan plus busulphan in conditioning to autologous stem cell transplantation for low-risk multiple myeloma.

Hematol J 2004 ;5(2):118-22

Department of Biomedical Sciences and Human Oncology, Section of Internal Medicine and Clinical Oncology, University of Bari, Bari, Italy.

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http://dx.doi.org/10.1038/sj.thj.6200369DOI Listing
November 2004

Transplantation of haploidentically mismatched stem cells for the treatment of malignant diseases.

Springer Semin Immunopathol 2004 Nov 11;26(1-2):155-68. Epub 2004 Sep 11.

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Via Brunamonti, 06123 Perugia, Italy.

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http://dx.doi.org/10.1007/s00281-004-0161-7DOI Listing
November 2004

Natural killer cells as a therapeutic tool in mismatched transplantation.

Best Pract Res Clin Haematol 2004 Sep;17(3):427-38

Division of Haematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Policlinico Monteluce, Via Brunamonti 06100, Perugia, Italy.

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http://dx.doi.org/10.1016/j.beha.2004.05.010DOI Listing
September 2004

Typical genomic imbalances in primary MALT lymphoma of the orbit.

J Pathol 2003 Aug;200(5):656-60

Haematology and Bone Marrow Transplantation Unit, Policlinico Monteluce, University of Perugia, via Brunamonti, 06123 Perugia, Italy.

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http://dx.doi.org/10.1002/path.1386DOI Listing
August 2003

Human homeobox gene HOXC13 is the partner of NUP98 in adult acute myeloid leukemia with t(11;12)(p15;q13).

Genes Chromosomes Cancer 2003 Apr;36(4):420-3

Hematology and Bone Marrow Transplantation Unit, University of Perugia, Policlinico Monteluce, via Brunamonti, 06123 Perugia, Italy.

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http://doi.wiley.com/10.1002/gcc.10182
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http://dx.doi.org/10.1002/gcc.10182DOI Listing
April 2003

Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants.

Science 2002 Mar;295(5562):2097-100

Department of Clinical and Experimental Medicine, Section of Hematology and Clinical Immunology, Perugia University School of Medicine, Perugia, Italy.

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http://dx.doi.org/10.1126/science.1068440DOI Listing
March 2002

Transplants across human leukocyte antigen barriers.

Semin Hematol 2002 Jan;39(1):48-56

Department of Hematology, University of Perugia, Perugia, Italy.

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January 2002

Philadelphia-positive acute lymphoblastic leukemia with multiple subclones including duplication of the Philadelphia chromosome and Abelson oncogene.

Cancer Genet Cytogenet 2002 Jan;132(1):46-50

Hematology and Bone Marrow Transplantation Unit, University of Perugia, Policlinico Monteluce, 06100, Perugia, Italy.

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http://dx.doi.org/10.1016/s0165-4608(01)00507-6DOI Listing
January 2002