Massimo F Martelli

Immune tolerance induction by nonmyeloablative haploidentical HSCT combining T-cell depletion and posttransplant cyclophosphamide.

Authors:

Franco Aversa Esther Bachar-Lustig Noga Or-Geva Lucia Prezioso Sabrina Bonomini Ilenia Manfra Alessandro Monti Chiara Schifano Yael Zlotnikov-Klionsky Massimo F Martelli Gabriella Sammarelli Maria Sassi Maurizio Soli Silvia Giuliodori Magda Benecchi Nicola Giuliani Frank Lohr Silvia Pratissoli Yair Reisner

Blood Adv 2017 Nov 30;1(24):2166-2175. Epub 2017 Oct 30.

Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.

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November 2017

Clinical-Grade-Expanded Regulatory T Cells Prevent Graft-versus-Host Disease While Allowing a Powerful T Cell-Dependent Graft-versus-Leukemia Effect in Murine Models.

Authors:

Beatrice Del Papa Loredana Ruggeri Elena Urbani Stefano Baldoni Debora Cecchini Tiziana Zei Roberta Iacucci Ostini Barbara Crescenzi Alessandra Carotti Antonio Pierini Paolo Sportoletti Paolo Di Bartolomeo Franca Falzetti Cristina Mecucci Andrea Velardi Massimo F Martelli Mauro Di Ianni

Biol Blood Marrow Transplant 2017 Nov 17;23(11):1847-1851. Epub 2017 Jul 17.

Department of Hematology, Transfusion Medicine and Biotechnologies, Ospedale Civile, Pescara, Italy; Department of Medicine and Aging Sciences, University of Chieti-Pescara, Italy. Electronic address:

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November 2017

Haploidentical transplants using ex vivo T-cell depletion.

Authors:

Massimo F Martelli Franco Aversa

Semin Hematol 2016 10 25;53(4):252-256. Epub 2016 Jul 25.

Hematology and Bone Marrow Transplantation Unit, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy.

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October 2016

Haploidentical hematopoietic transplantation from KIR ligand-mismatched donors with activating KIRs reduces nonrelapse mortality.

Authors:

Antonella Mancusi Loredana Ruggeri Elena Urbani Antonio Pierini Maria Speranza Massei Alessandra Carotti Adelmo Terenzi Franca Falzetti Antonella Tosti Fabiana Topini Silvia Bozza Luigina Romani Rita Tognellini Martin Stern Franco Aversa Massimo F Martelli Andrea Velardi

Blood 2015 May 13;125(20):3173-82. Epub 2015 Mar 13.

Division of Hematology and Clinical Immunology and Bone Marrow Transplant Program, Department of Medicine and.

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May 2015

Differences in Aspergillus-specific immune recovery between T-cell-replete and T-cell-depleted hematopoietic transplants.

Authors:

Katia Perruccio Fabiana Topini Antonella Tosti Maria Vittoria Gazzola Chiara Messina Massimo F Martelli Maurizio Caniglia Andrea Velardi Simone Cesaro

Eur J Haematol 2015 Dec 16;95(6):551-7. Epub 2015 Mar 16.

Pediatric Hematology Oncology, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.

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December 2015

HLA-haploidentical transplantation with regulatory and conventional T-cell adoptive immunotherapy prevents acute leukemia relapse.

Authors:

Massimo F Martelli Mauro Di Ianni Loredana Ruggeri Franca Falzetti Alessandra Carotti Adelmo Terenzi Antonio Pierini Maria Speranza Massei Lucia Amico Elena Urbani Beatrice Del Papa Tiziana Zei Roberta Iacucci Ostini Debora Cecchini Rita Tognellini Yair Reisner Franco Aversa Brunangelo Falini Andrea Velardi

Blood 2014 Jul 12;124(4):638-44. Epub 2014 Jun 12.

Division of Hematology and Clinical Immunology, Department of Medicine, University of Perugia, Perugia, Italy;

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July 2014

Experts' considerations on HLA-haploidentical stem cell transplantation.

Authors:

Francesca Patriarca Leo Luznik Marta Medeot Marco Zecca Andrea Bacigalupo Paolo Di Bartolomeo William Arcese Paolo Corradini Fabio Ciceri Luca Vago Christopher G Kanakry Katharina Fleischhauer Massimo F Martelli Alberto Bosi Alessandro Rambaldi Simone Cesaro Domenico Russo Renato Fanin

Eur J Haematol 2014 Sep 26;93(3):187-97. Epub 2014 Apr 26.

Department of Hematology, Stem Cell Transplant Unit, DISM, University Hospital, Udine, Italy.

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September 2014

"Designed" grafts for HLA-haploidentical stem cell transplantation.

Authors:

Massimo F Martelli Mauro Di Ianni Loredana Ruggeri Antonio Pierini Franca Falzetti Alessandra Carotti Adelmo Terenzi Yair Reisner Franco Aversa Brunangelo Falini Andrea Velardi

Blood 2014 Feb 20;123(7):967-73. Epub 2013 Dec 20.

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy;

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February 2014

The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model.

Authors:

Paolo Sportoletti Emanuela Varasano Roberta Rossi Oxana Bereshchenko Debora Cecchini Ilaria Gionfriddo Niccolò Bolli Enrico Tiacci Tamara Intermesoli Pamela Zanghì Arianna Masciulli Maria Paola Martelli Franca Falzetti Massimo F Martelli Brunangelo Falini

Blood 2013 Apr 22;121(17):3447-58. Epub 2013 Feb 22.

Institute of Hematology, University of Perugia, Ospedale S. Mariadella Misericordia, Perugia, Italy.

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April 2013

Mutational landscape of AML with normal cytogenetics: biological and clinical implications.

Authors:

Maria Paola Martelli Paolo Sportoletti Enrico Tiacci Massimo F Martelli Brunangelo Falini

Blood Rev 2013 Jan 20;27(1):13-22. Epub 2012 Dec 20.

Institute of Hematology, University of Perugia, Perugia, Italy.

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January 2013

Haploidentical hematopoietic stem cell transplantation with a megadose T-cell-depleted graft: harnessing natural and adaptive immunity.

Authors:

Franco Aversa Massimo F Martelli Andrea Velardi

Semin Oncol 2012 Dec;39(6):643-52

Section of Hematology and BMT Unit, University of Parma, Parma, Italy.

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December 2012

Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction.

Authors:

Beatrice Del Papa Paolo Sportoletti Debora Cecchini Emanuela Rosati Chiara Balucani Stefano Baldoni Katia Fettucciari Pierfrancesco Marconi Massimo F Martelli Franca Falzetti Mauro Di Ianni

Eur J Immunol 2013 Jan 5;43(1):182-7. Epub 2012 Dec 5.

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Perugia, Italy.

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January 2013

T regulatory cell separation for clinical application.

Authors:

Mauro Di Ianni Beatrice Del Papa Tiziana Zei Roberta Iacucci Ostini Debora Cecchini Maria Grazia Cantelmi Stefano Baldoni Paolo Sportoletti Laura Cavalli Alessandra Carotti Antonio Pierini Brunangelo Falini Massimo F Martelli Franca Falzetti

Transfus Apher Sci 2012 Oct 12;47(2):213-6. Epub 2012 Jul 12.

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy.

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October 2012

High-dose thiotepa, etoposide and carboplatin as conditioning regimen for autologous stem cell transplantation in patients with high-risk Hodgkin's lymphoma.

Authors:

Mauro Di Ianni Stelvio Ballanti Giuseppe Iodice Antonia Reale Franca Falzetti Olivia Minelli Gabriella Serio Massimo F Martelli Franco Dammacco Angelo Vacca Roberto Ria

Hematology 2012 Jan;17(1):23-7

Department of Clinical and Experimental Medicine, Section of Hematology and Clinical Immunology, University of Perugia Medical School, I-06100 Perugia, Italy.

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January 2012

High-dose thiotepa, etoposide and carboplatin as conditioning regimen for autologous stem cell transplantation in patients with high-risk non-Hodgkin lymphoma.

Authors:

Franca Falzetti Mauro Di Ianni Stelvio Ballanti Giuseppe Iodice Antonia Reale Olivia Minelli Gabriella Serio Massimo F Martelli Franco Dammacco Angelo Vacca Roberto Ria

Clin Exp Med 2012 Sep 18;12(3):165-71. Epub 2011 Sep 18.

Department of Clinical and Experimental Medicine, Section of Hematology and Clinical Immunology, University of Perugia Medical School, Perugia, Italy.

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September 2012

Immunoselection and clinical use of T regulatory cells in HLA-haploidentical stem cell transplantation.

Authors:

Mauro Di Ianni Franca Falzetti Alessandra Carotti Adelmo Terenzi Beatrice Del Papa Katia Perruccio Loredana Ruggeri Paolo Sportoletti Emanuela Rosati Pierfrancesco Marconi Brunangelo Falini Yair Reisner Andrea Velardi Franco Aversa Massimo F Martelli

Best Pract Res Clin Haematol 2011 Sep 29;24(3):459-66. Epub 2011 Jun 29.

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy.

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September 2011

The importance of bone marrow transplantation for patients who do not have a matched sibling donor.

Authors:

Yair Reisner Massimo F Martelli

Best Pract Res Clin Haematol 2011 Sep 29;24(3):323-4. Epub 2011 Jul 29.

Department of Immunology, Weizmann Institute of Science, Rehovot, Italy.

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September 2011

Haploidentical hematopoietic transplantation: current status and future perspectives.

Authors:

Yair Reisner David Hagin Massimo F Martelli

Blood 2011 Dec 14;118(23):6006-17. Epub 2011 Sep 14.

Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.

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December 2011

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation.

Blood 2011 Apr 3;117(14):3921-8. Epub 2011 Feb 3.

Hematology and Clinical Immunology Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy.

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April 2011

NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL.

Authors:

Paolo Sportoletti Stefano Baldoni Laura Cavalli Beatrice Del Papa Elisabetta Bonifacio Raffaella Ciurnelli Alain Sylvin Bell Ambra Di Tommaso Emanuela Rosati Barbara Crescenzi Cristina Mecucci Isabella Screpanti Pierfrancesco Marconi Massimo F Martelli Mauro Di Ianni Franca Falzetti

Br J Haematol 2010 Nov 31;151(4):404-6. Epub 2010 Aug 31.

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November 2010

CD34+ cells from AML with mutated NPM1 harbor cytoplasmic mutated nucleophosmin and generate leukemia in immunocompromised mice.

Blood 2010 Nov 15;116(19):3907-22. Epub 2010 Jul 15.

Institute of Hematology and Clinical Immunology, University of Perugia, Perugia, Italy.

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November 2010

Thymosin alpha1 to harness immunity to pathogens after haploidentical hematopoietic transplantation.

Authors:

Katia Perruccio Pierluigi Bonifazi Fabiana Topini Antonella Tosti Silvia Bozza Teresa Aloisi Alessandra Carotti Franco Aversa Massimo F Martelli Luigina Romani Andrea Velardi

Ann N Y Acad Sci 2010 Apr;1194:153-61

Division of Hematology and Clinical Immunology, University of Perugia, Perugia, Italy.

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April 2010

A NUP98-positive acute myeloid leukemia with a t(11;12)(p15;q13) without HOXC cluster gene involvement.

Authors:

Roberta La Starza Lucia Brandimarte Valentina Pierini Valeria Nofrini Paolo Gorello Barbara Crescenzi Laura Berchicci Caterina Matteucci Silvia Romoli Donatella Beacci Roberto Rosati Massimo F Martelli Cristina Mecucci

Cancer Genet Cytogenet 2009 Sep;193(2):109-11

Hematology and Bone Marrow Transplantation Unit, University of Perugia, Ematologia e Trapianto di Midollo Osseo, Ospedale S.M. della Misericordia, (Padiglione B, piano -2), S. Andrea delle Fratte, 06156 Perugia, Italy.

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September 2009

A new genetic lesion in B-CLL: a NOTCH1 PEST domain mutation.

Authors:

Mauro Di Ianni Stefano Baldoni Emanuela Rosati Raffaella Ciurnelli Laura Cavalli Massimo F Martelli PierFrancesco Marconi Isabella Screpanti Franca Falzetti

Br J Haematol 2009 Sep 10;146(6):689-91. Epub 2009 Jul 10.

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September 2009

Cytoplasmic nucleophosmin is not detected in blastic plasmacytoid dendritic cell neoplasm.

Authors:

Fabio Facchetti Stefano A Pileri Claudio Agostinelli Maria Paola Martelli Marco Paulli Adriano Venditti Massimo F Martelli Brunangelo Falini

Haematologica 2009 Feb 9;94(2):285-8. Epub 2008 Dec 9.

Institute of Pathology, Spedali Civili, University of Brescia, Brescia.

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February 2009

Clinical impact of natural killer cell reconstitution after allogeneic hematopoietic transplantation.

Authors:

Andrea Velardi Loredana Ruggeri Antonella Mancusi Emanuela Burchielli Katia Perruccio Franco Aversa Massimo F Martelli

Semin Immunopathol 2008 Dec 11;30(4):489-503. Epub 2008 Nov 11.

Division of Hematology and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Perugia, Ospedale Santa Maria della Misericordia, Perugia, Italy.

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December 2008