Publications by authors named "Massimo Cristofanilli"

100Publications

Corrigendum to "Challenges and opportunities of cfDNA analysis implementation in clinical practice: Perspective of the International Society of Liquid Biopsy (ISLB)" [Crit. Rev. Oncol. Hematol. 151 (July) (2020) 102978].

Crit Rev Oncol Hematol 2020 Oct 18;154:103058. Epub 2020 Aug 18.

Centre for Genomics and Oncological Research - GENYO, Pfizer, University of Granada, Andalusian Regional Government, Granada, Spain; Bio-Health Research Institute (Instituto de Investigación Biosanitaria ibs. GRANADA), Spain; Complejo Hospitalario Universitario Granada (CHUG), Department of Medical Oncology, University of Granada, Granada, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2020.103058DOI Listing
October 2020

Landscape of circulating tumour DNA in metastatic breast cancer.

EBioMedicine 2020 Aug 21;58:102914. Epub 2020 Jul 21.

Division of Hematology and Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, United States; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, 710N. Fairbanks Court- Olson Pavilion, Suite 8-250A, Chicago, IL 60611, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2020.102914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7381501PMC
August 2020

Minimal Residual Disease in Patients With Nonmetastatic Triple-Negative Breast Cancer: Positive, Negative, or a More Complex Issue?

JAMA Oncol 2020 Jul 9. Epub 2020 Jul 9.

Division of Hematology and Oncology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

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http://dx.doi.org/10.1001/jamaoncol.2020.2285DOI Listing
July 2020

Challenges and opportunities of cfDNA analysis implementation in clinical practice: Perspective of the International Society of Liquid Biopsy (ISLB).

Crit Rev Oncol Hematol 2020 Jul 5;151:102978. Epub 2020 May 5.

Centre for Genomics and Oncological Research - GENYO, Pfizer, University of Granada, Andalusian Regional Government, Granada, Spain; Bio-Health Research Institute (Instituto de Investigación Biosanitaria ibs. GRANADA), Spain; Complejo Hospitalario Universitario Granada (CHUG), Department of Medical Oncology, University of Granada, Granada, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2020.102978DOI Listing
July 2020

The Landscape of Targeted Therapies in TNBC.

Cancers (Basel) 2020 Apr 8;12(4). Epub 2020 Apr 8.

Division of Hematology Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.3390/cancers12040916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7226210PMC
April 2020

Hormone Receptor-Positive/Human Epidermal Growth Receptor 2-Negative Metastatic Breast Cancer in Young Women: Emerging Data in the Era of Molecularly Targeted Agents.

Oncologist 2020 Jun 16;25(6):e900-e908. Epub 2020 Mar 16.

Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1634/theoncologist.2019-0729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288640PMC
June 2020

Regulation of KLF4 by posttranslational modification circuitry in endocrine resistance.

Cell Signal 2020 Jun 19;70:109574. Epub 2020 Feb 19.

Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2020.109574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511032PMC
June 2020

Performance of a novel Next Generation Sequencing circulating tumor DNA (ctDNA) platform for the evaluation of samples from patients with metastatic breast cancer (MBC).

Crit Rev Oncol Hematol 2020 Jan 23;145:102856. Epub 2019 Dec 23.

Department of Medicine, Division of Hematology and Oncology, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.critrevonc.2019.102856DOI Listing
January 2020

Time for a shift in molecular down staging in luminal breast cancer.

Lancet Oncol 2020 01 11;21(1):2-3. Epub 2019 Dec 11.

Department of Medicine, Division of Hematology and Oncology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30806-XDOI Listing
January 2020

A novel strategy to block mitotic progression for targeted therapy.

EBioMedicine 2019 Nov 25;49:40-54. Epub 2019 Oct 25.

Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, USA; Department of Pharmacology, Northwestern University Feinberg School of Medicine, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, USA; Chemical of Life Processes Institute, Northwestern University, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945239PMC
November 2019

The curious phenomenon of dual-positive circulating cells: Longtime overlooked tumor cells.

Semin Cancer Biol 2020 02 15;60:344-350. Epub 2019 Oct 15.

Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2019.10.008DOI Listing
February 2020

Current state of clinical trials in breast cancer brain metastases.

Neurooncol Pract 2019 Sep 11;6(5):392-401. Epub 2019 Feb 11.

Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1093/nop/npz003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753353PMC
September 2019

Emerging Role of Genomics and Cell-Free DNA in Breast Cancer.

Curr Treat Options Oncol 2019 06 29;20(8):68. Epub 2019 Jun 29.

Department of Medicine, Division of Hematology and Oncology, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, 710 N Fairbanks Court, Suite 8-250A, Chicago, IL, 60611, USA.

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http://dx.doi.org/10.1007/s11864-019-0667-9DOI Listing
June 2019

Recent advances with cyclin-dependent kinase inhibitors: therapeutic agents for breast cancer and their role in immuno-oncology.

Expert Rev Anticancer Ther 2019 07 20;19(7):569-587. Epub 2019 Jun 20.

a Pennsylvania Cancer and Regenerative Medicine Research Center , Baruch S. Blumberg Institute, Pennsylvania Biotechnology Center , Wynnewood , PA , USA.

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http://dx.doi.org/10.1080/14737140.2019.1615889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834352PMC
July 2019

A novel small-molecule antagonizes PRMT5-mediated KLF4 methylation for targeted therapy.

EBioMedicine 2019 Jun 14;44:98-111. Epub 2019 May 14.

Department of Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, United States; Department of Pharmacology, Northwestern University Feinberg School of Medicine, United States; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S23523964193031
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http://dx.doi.org/10.1016/j.ebiom.2019.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6604046PMC
June 2019

Elevated serum levels of sialyl Lewis X (sLe) and inflammatory mediators in patients with breast cancer.

Breast Cancer Res Treat 2019 Aug 3;176(3):545-556. Epub 2019 May 3.

Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, 1220 Holcombe Blvd, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1007/s10549-019-05258-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6653624PMC
August 2019

Palbociclib and Fulvestrant in Breast Cancer. Reply.

N Engl J Med 2019 Feb;380(8):797

Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL.

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http://dx.doi.org/10.1056/NEJMc1816595DOI Listing
February 2019

Circulating tumor DNA analysis in breast cancer: Is it ready for prime-time?

Cancer Treat Rev 2019 Feb 11;73:73-83. Epub 2019 Jan 11.

Department of Medicine (DAME), University of Udine, Italy; Department of Medical Oncology, Centro di Riferimento Oncologico (CRO), IRCCS, Aviano, PN, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S03057372193000
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http://dx.doi.org/10.1016/j.ctrv.2019.01.004DOI Listing
February 2019

Overall Survival with Palbociclib and Fulvestrant in Advanced Breast Cancer.

N Engl J Med 2018 Nov 20;379(20):1926-1936. Epub 2018 Oct 20.

From the Institute of Cancer Research and Royal Marsden Hospital, London (N.C.T.); David Geffen School of Medicine at University of California, Los Angeles, Santa Monica (D.J.S.), and Pfizer Oncology, San Diego (X.H.) - both in California; National Cancer Center, Goyang-si, Gyeonggi-do (J.R.), and Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul (S.-A.I.) - both in South Korea; Dnipropetrovsk Medical Academy, City Multiple-Discipline Clinical Hospital 4, Dnipropetrovsk, Ukraine (I.B.); National Hospital Organization Osaka National Hospital, Osaka (N.M.), and Aichi Cancer Center Hospital, Nagoya (H.I.) - both in Japan; Istituto Europeo di Oncologia (M. Colleoni) and Pfizer Oncology (C.G.) - both in Milan; Abramson Cancer Center, University of Pennsylvania, Philadelphia (A.D.), and Pfizer Oncology, Collegeville (C.H.B.) - both in Pennsylvania; Peter MacCallum Cancer Centre, University of Melbourne, Melbourne, VIC, Australia (S. Loi); Tom Baker Cancer Centre, University of Calgary, Calgary, AB, Canada (S.V.); Brustzentrum der Universität München, Munich (N.H.), and the German Breast Group, Neu-Isenburg (S. Loibl) - both in Germany; Institut Gustave Roussy, Villejuif, France (F.A.); Pfizer Oncology, Cambridge, MA (K.P.T.); and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Feinberg School of Medicine, Chicago (M. Cristofanilli).

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http://www.nejm.org/doi/10.1056/NEJMoa1810527
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http://dx.doi.org/10.1056/NEJMoa1810527DOI Listing
November 2018

Identification of Incidental Germline Mutations in Patients With Advanced Solid Tumors Who Underwent Cell-Free Circulating Tumor DNA Sequencing.

J Clin Oncol 2018 Oct 19:JCO1800328. Epub 2018 Oct 19.

Thomas P. Slavin, Kar Wing Kevin Tsang, Susan L. Neuhausen, Stacy W. Gray, and Jeffrey N. Weitzel, City of Hope, Duarte; Kimberly C. Banks, Darya Chudova, Justin I. Odegaard, Rebecca J. Nagy, Christine E. Lee, and Richard B. Lanman, Guardant Health, Redwood City; Razelle Kurzrock, University of California, San Diego, Moores Cancer Center, San Diego, CA; Geoffrey R. Oxnard, Dana-Farber Cancer Institute; Aditya Bardia, Massachusetts General Hospital Cancer Center and Harvard Medical School, Boston, MA; Massimo Cristofanilli, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL; Angel A. Rodriguez, Houston Methodist Hospital; Funda Meric-Bernstam, The University of Texas MD Anderson Cancer Center, Houston, TX; Brian Leyland-Jones, Avera Cancer Institute, Sioux Falls, SD; Mike F. Janicek, Arizona Oncology Associates Gynecology Oncology, Scottsdale, AZ; Michael Lilly, Medical University of South Carolina, Charleston, SC; and Guru Sonpavde, The University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, AL.

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http://ascopubs.org/doi/10.1200/JCO.18.00328
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http://dx.doi.org/10.1200/JCO.18.00328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286162PMC
October 2018

From the Past to the Present: Insurer Coverage Frameworks for Next-Generation Tumor Sequencing.

Value Health 2018 09 3;21(9):1062-1068. Epub 2018 Aug 3.

Department of Clinical Pharmacy, UCSF Center for Translational and Policy Research on Personalized Medicine (TRANSPERS), University of California San Francisco, San Francisco, CA, USA; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S10983015183226
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http://dx.doi.org/10.1016/j.jval.2018.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374027PMC
September 2018

Impeding Circulating Tumor Cell Reseeding Decelerates Metastatic Progression and Potentiates Chemotherapy.

Mol Cancer Res 2018 12 16;16(12):1844-1854. Epub 2018 Aug 16.

Department of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1541-7786.MCR-18-0302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279516PMC
December 2018

NQO1 regulates mitotic progression and response to mitotic stress through modulating SIRT2 activity.

Free Radic Biol Med 2018 10 13;126:358-371. Epub 2018 Aug 13.

Laboratory for Molecular Cancer Biology, Department of Radiation Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2018.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170003PMC
October 2018

Regarding the Congruence Between 2 Circulating Tumor DNA Sequencing Assays.

JAMA Oncol 2018 10;4(10):1430

International Society of Liquid Biopsy, Granada, Spain.

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http://oncology.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamaoncol.2018.2320DOI Listing
October 2018

Phase I study of alpelisib (BYL-719) and trastuzumab emtansine (T-DM1) in HER2-positive metastatic breast cancer (MBC) after trastuzumab and taxane therapy.

Breast Cancer Res Treat 2018 Sep 30;171(2):371-381. Epub 2018 May 30.

Lynn Sage Breast Cancer Program, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, 676 N St. Clair St. Suite 850, Chicago, IL, 60611, USA.

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http://link.springer.com/10.1007/s10549-018-4792-0
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http://dx.doi.org/10.1007/s10549-018-4792-0DOI Listing
September 2018

Decreased expression of microRNA-26b in locally advanced and inflammatory breast cancer.

Hum Pathol 2018 07 22;77:121-129. Epub 2018 Apr 22.

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX; Morgan Welch Inflammatory Breast Cancer Research Program and Clinic, The University of Texas MD Anderson Cancer Center, Houston, TX. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2018.04.002DOI Listing
July 2018

Comparing the Performances of Magnetic Resonance Imaging Size vs Pharmacokinetic Parameters to Predict Response to Neoadjuvant Chemotherapy and Survival in Patients With Breast Cancer.

Curr Probl Diagn Radiol 2019 May - Jun;48(3):235-240. Epub 2018 Mar 28.

Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, TX.

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http://dx.doi.org/10.1067/j.cpradiol.2018.03.003DOI Listing
August 2019

Perspective on Circulating Tumor Cell Clusters: Why It Takes a Village to Metastasize.

Cancer Res 2018 02 2;78(4):845-852. Epub 2018 Feb 2.

Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-2748DOI Listing
February 2018

Emerging Innovative Therapeutic Approaches Leveraging Cyclin-Dependent Kinase Inhibitors to Treat Advanced Breast Cancer.

Clin Pharmacol Ther 2018 06 30;103(6):1009-1019. Epub 2018 Jan 30.

Department of Medicine-Hematology and Oncology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

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http://dx.doi.org/10.1002/cpt.965DOI Listing
June 2018

Cell-Free DNA and Circulating Tumor Cells: Comprehensive Liquid Biopsy Analysis in Advanced Breast Cancer.

Clin Cancer Res 2018 02 27;24(3):560-568. Epub 2017 Nov 27.

Department of Medicine-Hematology and Oncology, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-2092DOI Listing
February 2018

Response rate as a potential surrogate for survival and efficacy in patients treated with novel immune checkpoint inhibitors: A meta-regression of randomised prospective studies.

Eur J Cancer 2017 11 19;86:257-265. Epub 2017 Oct 19.

Department of Medical, Surgery and Health Sciences, University of Trieste, Piazza Ospitale 1, 34129 Trieste, Italy; Breast Cancer Unit and Translational Research Unit, ASST Cremona, Viale Concordia 1, 26100 Cremona, Italy.

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http://dx.doi.org/10.1016/j.ejca.2017.09.018DOI Listing
November 2017

Prognostic values of cancer associated macrophage-like cells (CAML) enumeration in metastatic breast cancer.

Breast Cancer Res Treat 2017 Oct 7;165(3):733-741. Epub 2017 Jul 7.

Department of Medicine-Hematology and Oncology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.

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http://link.springer.com/10.1007/s10549-017-4372-8
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http://dx.doi.org/10.1007/s10549-017-4372-8DOI Listing
October 2017

Detection of Activating Estrogen Receptor Gene () Mutations in Single Circulating Tumor Cells.

Clin Cancer Res 2017 Oct 5;23(20):6086-6093. Epub 2017 Jul 5.

Department of Cancer Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-17-1173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641250PMC
October 2017

Concordance of Genomic Alterations by Next-Generation Sequencing in Tumor Tissue versus Circulating Tumor DNA in Breast Cancer.

Mol Cancer Ther 2017 07 26;16(7):1412-1420. Epub 2017 Apr 26.

Developmental Therapeutics Program of Division of Hematology Oncology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0061DOI Listing
July 2017

The Growing Role of CDK4/6 Inhibitors in Treating Hormone Receptor-Positive Advanced Breast Cancer.

Curr Treat Options Oncol 2017 01;18(1)

Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, 710 North Fairbanks Ct, Suite 8-250a, Chicago, IL, USA.

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http://dx.doi.org/10.1007/s11864-017-0443-7DOI Listing
January 2017

Targeting Epidermal Growth Factor Receptor in triple negative breast cancer: New discoveries and practical insights for drug development.

Cancer Treat Rev 2017 Feb 5;53:111-119. Epub 2017 Jan 5.

Developmental Therapeutics Program, Division of Hematology/Oncology, Feinberg School of Medicine, Chicago, USA; Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, USA.

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http://dx.doi.org/10.1016/j.ctrv.2016.12.010DOI Listing
February 2017

Developmental therapeutics for inflammatory breast cancer: Biology and translational directions.

Oncotarget 2017 Feb;8(7):12417-12432

Developmental Therapeutics Program, Division of Hematology/Oncology, Feinberg School of Medicine, Chicago, United States of America.

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http://dx.doi.org/10.18632/oncotarget.13778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355355PMC
February 2017

Metastatic breast cancer: focus on endocrine sensitivity.

Lancet 2016 12 29;388(10063):2961-2962. Epub 2016 Nov 29.

Department of Medicine, Division of Hematology and Oncology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(16)32418-7DOI Listing
December 2016

Longitudinally collected CTCs and CTC-clusters and clinical outcomes of metastatic breast cancer.

Breast Cancer Res Treat 2017 01 22;161(1):83-94. Epub 2016 Oct 22.

Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, 19107, USA.

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http://dx.doi.org/10.1007/s10549-016-4026-2DOI Listing
January 2017

Detection and Characterization of Circulating Tumor Associated Cells in Metastatic Breast Cancer.

Int J Mol Sci 2016 Sep 30;17(10). Epub 2016 Sep 30.

Department of Medicine-Hematology and Oncology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.3390/ijms17101665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085698PMC
September 2016

Real-time HER2 status detected on circulating tumor cells predicts different outcomes of anti-HER2 therapy in histologically HER2-positive metastatic breast cancer patients.

BMC Cancer 2016 07 25;16:526. Epub 2016 Jul 25.

Translational Medicine Center, Laboratory of Oncology, Affiliated Hospital of Academy of Military Medical Sciences, 8 Dongdajie, Beijing, 100071, China.

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http://dx.doi.org/10.1186/s12885-016-2578-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4960713PMC
July 2016

GSK-3 inhibition overcomes chemoresistance in human breast cancer.

Cancer Lett 2016 10 14;380(2):384-92. Epub 2016 Jul 14.

Center for Developmental Therapeutics, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, 2170 Campus Drive, Evanston, IL 60208, USA; Chemistry of Life Processes Institute, Northwestern University, 2170 Campus Drive, Evanston, IL, 60208, USA; Northwestern Medicine Developmental Therapeutics Institute, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Olson Pavilion, 233 East Superior Street, Chicago, IL 60611, USA; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Searle Building 8-510, 320 East Superior Street, Chicago, IL 60611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786372PMC
October 2016

Prospective changes in global DNA methylation and cancer incidence and mortality.

Br J Cancer 2016 08 28;115(4):465-72. Epub 2016 Jun 28.

Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, 680 N. Lake Shore Drive, Suite 1400, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1038/bjc.2016.205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985350PMC
August 2016

Plasma ESR1 Mutations and the Treatment of Estrogen Receptor-Positive Advanced Breast Cancer.

J Clin Oncol 2016 09 6;34(25):2961-8. Epub 2016 Jun 6.

Charlotte Fribbens, Ben O'Leary, Sarah Hrebien, Isaac Garcia-Murillas, Matthew Beaney, Mitch Dowsett, and Nicholas C. Turner, Institute of Cancer Research; Charlotte Fribbens, Ben O'Leary, Stephen R.D. Johnston, and Nicholas C. Turner, Royal Marsden Hospital; Lucy Kilburn and Judith M. Bliss, The Institute of Cancer Research Clinical Trials and Statistics Unit, London, UK; Massimo Cristofanilli, Thomas Jefferson University, Philadelphia, PA; Fabrice Andre, Institut Gustave Roussy, Villejuif, France; Sherene Loi, University of Melbourne, Melbourne, Australia; Sibylle Loibl, German Breast Group, Neu-Isenburg, Germany; and John Jiang, Cynthia Huang Bartlett, and Maria Koehler, Pfizer, New York, NY.

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http://dx.doi.org/10.1200/JCO.2016.67.3061DOI Listing
September 2016

Genomic and Immunological Tumor Profiling Identifies Targetable Pathways and Extensive CD8+/PDL1+ Immune Infiltration in Inflammatory Breast Cancer Tumors.

Mol Cancer Ther 2016 07 19;15(7):1746-56. Epub 2016 Apr 19.

Translational R&D Oncology Group, Quintiles, Westmont, Illinois. Department of Pharmacology, University of Illinois at Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/1535-7163.MCT-15-0353DOI Listing
July 2016