Publications by authors named "Massimo C Fantini"

35Publications

The Role of Gut Microbiota Biomodulators on Mucosal Immunity and Intestinal Inflammation.

Cells 2020 05 16;9(5). Epub 2020 May 16.

Department of Experimental Oncology, IEO European Institute of Oncology IRCCS, 20139 Milan, Italy.

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http://dx.doi.org/10.3390/cells9051234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7291275PMC
May 2020

Response Assessed by Ultrasonography as Target of Biological Treatment for Crohn's Disease.

Clin Gastroenterol Hepatol 2020 Aug 20;18(9):2030-2037. Epub 2019 Dec 20.

Gastroenterology Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2019.10.042DOI Listing
August 2020

The Resolution of Intestinal Inflammation: The Peace-Keeper's Perspective.

Cells 2019 04 11;8(4). Epub 2019 Apr 11.

Dep. of Systems Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133 Rome, Italy.

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http://dx.doi.org/10.3390/cells8040344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523641PMC
April 2019

Infection Decreases Smad7 Expression in Intestinal CD4 T Cells, Which Allows TGF-β to Induce IL-10-Producing Regulatory T Cells That Block Colitis.

J Immunol 2019 04 8;202(8):2473-2481. Epub 2019 Mar 8.

Division of Gastroenterology/Hepatology, Department of Internal Medicine, Tufts Medical Center, Boston, MA 02111;

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http://dx.doi.org/10.4049/jimmunol.1801392DOI Listing
April 2019

Update on the Therapeutic Efficacy of Tregs in IBD: Thumbs up or Thumbs down?

Inflamm Bowel Dis 2017 10;23(10):1682-1688

Department of Systems Medicine, University of Rome "Tor Vergata," Rome, Italy.

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http://dx.doi.org/10.1097/MIB.0000000000001272DOI Listing
October 2017

Mongersen, an oral SMAD7 antisense oligonucleotide, and Crohn's disease.

N Engl J Med 2015 Mar;372(12):1104-13

From the Department of Systems Medicine, University of Tor Vergata (G.M., M.C.F., S.O., L.B., F.P.), Gastroenterology Unit-Azienda Ospedaliera San Camillo-Forlanini (M.L.S.), Inflammatory Bowel Disease Unit, Complesso Integrato Columbus, Catholic University (A.A.), and Inflammatory Bowel Disease Unit, Department of Internal Medicine, Division of Gastroenterology, Sandro Pertini Hospital Rome (R.P.), Rome, Department of Surgery, L. Sacco University Hospital (S.A., M.F.), Department of Pathophysiology and Transplantation, University of Milan and Ospedale Policlinico di Milano (F. Caprioli), and Department of Biomedical Sciences for Health, University of Milan, and Gastroenterology Unit, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Policlinico San Donato, San Donato Milanese (M.V.), Milan, First Department of Internal Medicine, St. Matteo Hospital Foundation, University of Pavia, Pavia (A.D.S., G.R.C.), Gastroenterologia, Università Federico II di Napoli, Naples (F. Castiglione), Dipartimento di Scienze Chirurgiche Oncologiche e Gastroenterologiche-Unita' Operativa di Gastroenterologia-Universita' degli Studi di Padova, Padua (G.C.S.), Department of Medical and Surgical Specialties, Gastroenterology SOD2, Azienda Ospedaliero Universitaria Careggi, Florence (F.R.), Division of Gastroenterology, Casa Sollievo Sofferenza Hospital, IRCCS, San Giovanni Rotondo (F.B.), Department of Internal Medicine, Gastroenterology and Hepatology Unit, University of Genoa, Genoa (V.S.), and the Division of Internal Medicine Villa Sofia-Cervello Hospital, University of Palermo, Palermo (A.O.) - all in Italy; and the Department of Medicine, Medical Clinic 1, University of Erlangen-Nürnberg, Erlangen, Germany (M.F.N., R.A.).

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http://dx.doi.org/10.1056/NEJMoa1407250DOI Listing
March 2015

Smad7 induces plasticity in tumor-infiltrating Th17 cells and enables TNF-alpha-mediated killing of colorectal cancer cells.

Carcinogenesis 2014 Jul 30;35(7):1536-46. Epub 2014 Jan 30.

Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy, First Medical Clinic, University of Erlangen, Erlangen, Germany and Barts and the London School of Medicine and Dentistry, London, UK

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http://dx.doi.org/10.1093/carcin/bgu027DOI Listing
July 2014

Smad7 expression in T cells prevents colitis-associated cancer.

Cancer Res 2011 Dec 25;71(24):7423-32. Epub 2011 Oct 25.

Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1895DOI Listing
December 2011

Common immunologic mechanisms in inflammatory bowel disease and spondylarthropathies.

World J Gastroenterol 2009 May;15(20):2472-8

Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2686905PMC
http://dx.doi.org/10.3748/wjg.15.2472DOI Listing
May 2009

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

Gastroenterology 2009 Apr 27;136(4):1308-16, e1-3. Epub 2008 Dec 27.

Department of Internal Medicine, University of Rome Tor Vergata, Rome, Italy.

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http://dx.doi.org/10.1053/j.gastro.2008.12.053DOI Listing
April 2009

Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.

Blood 2009 Apr 7;113(15):3512-9. Epub 2009 Jan 7.

Department of Internal Medicine & Centre of Excellence for Genomic Risk Assessment in Multifactorial and Complex Diseases, University Tor Vergata of Rome, Rome, Italy.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2008-08-17
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http://dx.doi.org/10.1182/blood-2008-08-172767DOI Listing
April 2009

Cytokines: from gut inflammation to colorectal cancer.

Curr Drug Targets 2008 May;9(5):375-80

Department of Internal Medicine, University Tor Vergata of Rome, Rome, Italy.

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http://dx.doi.org/10.2174/138945008784221206DOI Listing
May 2008

Regulation of gut inflammation and th17 cell response by interleukin-21.

Gastroenterology 2008 Apr 17;134(4):1038-48. Epub 2008 Jan 17.

Dipartimento di Medicina Interna e Centro di Eccellenza per lo studio delle malattie complesse e multifattoriali, Università Tor Vergata, Rome.

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http://dx.doi.org/10.1053/j.gastro.2008.01.041DOI Listing
April 2008

New players in the cytokine orchestra of inflammatory bowel disease.

Inflamm Bowel Dis 2007 Nov;13(11):1419-23

Department of Internal Medicine, University Tor Vergata of Rome, Rome, Italy.

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https://academic.oup.com/ibdjournal/article/13/11/1419-1423/
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http://dx.doi.org/10.1002/ibd.20212DOI Listing
November 2007

In vitro generation of CD4+ CD25+ regulatory cells from murine naive T cells.

Nat Protoc 2007 ;2(7):1789-94

Division of Gastroenterology, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy.

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http://dx.doi.org/10.1038/nprot.2007.258DOI Listing
September 2007

IL-27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1.

Eur J Immunol 2007 Jul;37(7):1809-16

Laboratory of Immunology, I Medical Clinic, University of Mainz, Mainz, Germany.

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http://dx.doi.org/10.1002/eji.200636896DOI Listing
July 2007

Drug insight: novel small molecules and drugs for immunosuppression.

Nat Clin Pract Gastroenterol Hepatol 2006 Nov;3(11):633-44

University of Rome Tor Vergata, Italy.

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http://dx.doi.org/10.1038/ncpgasthep0611DOI Listing
November 2006

TGF-beta as a T cell regulator in colitis and colon cancer.

Cytokine Growth Factor Rev 2006 Feb-Apr;17(1-2):97-106. Epub 2005 Nov 18.

Laboratory of Clinical Immunology, I. Department of Medicine, University of Mainz, Obere Zahlbacher Str. 63, 55131 Mainz, Germany.

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http://dx.doi.org/10.1016/j.cytogfr.2005.09.004DOI Listing
January 2009

Angiogenesis, immune system and growth factors: new targets in colorectal cancer therapy.

Expert Rev Anticancer Ther 2005 Aug;5(4):681-94

Laboratory of Immunology, I Medical Clinic, Johannes Gutenberg University, 55131 Mainz, Obere Zahlbacher Str 63, Germany.

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http://dx.doi.org/10.1586/14737140.5.4.681DOI Listing
August 2005

Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7.

J Immunol 2004 May;172(9):5149-53

Laboratory of Immunology, I. Medical Clinic, Johannes Gutenberg University of Mainz, Mainz, Germany.

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http://dx.doi.org/10.4049/jimmunol.172.9.5149DOI Listing
May 2004