Publications by authors named "Masood Najafi"

2 Publications

  • Page 1 of 1

Prevalence and Associated Risk Factors of Hyperglycemia and Diabetes Mellitus Among HIV Positive Patients in Tehran, Iran.

Infect Disord Drug Targets 2019 ;19(3):304-309

Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran.

Background: The introduction of Antiretroviral Therapy (ART) has resulted in the emergence of some metabolic complications including hyperglycemia and diabetes mellitus among HIV positive patients. The aim of this study was to investigate the prevalence of hyperglycemia, diabetes mellitus and their associated risk factors in HIV positive patients.

Methods: This cross-sectional study was conducted on HIV positive patients who visited Voluntary Counseling and Testing (VCT) center of Imam Khomeini Hospital, Tehran, Iran (2004-2013). Medical records of patients were reviewed retrospectively. A logistic regression model was applied for analysis of the association between glycemic status and relevant risk factors.

Results: Out of 480 patients who were included in this study, 267 (55.6%) had hyperglycemia, including 28 (5.8%) with diabetes mellitus and 239 (49.8%) with pre-diabetes. The higher frequency of hyperglycemia, was found to be significantly associated with older age (OR for patients ˃40 years old, 2.260; 95% CI, 1.491, 3.247), male gender (OR, 1.555; 95% CI, 1.047, 2.311), higher Body Mass Index (OR for patients with BMI˃25 Kg/m², 1.706; 95% CI, 1.149, 2.531) and prolonged duration of HIV infection (OR for patients with duration of HIV infection ≥60 months, 2.027; 95% CI, 1.372, 2.992).

Conclusion: Hyperglycemia, especially pre-diabetes, is highly frequent among Iranian people living with HIV. Male gender, older age, prolonged duration of HIV infection, and higher BMI were associated with a higher prevalence of hyperglycemia. Hence, it is important to screen all HIV infected patients at the time of diagnosis and then periodically for hyperglycemia.
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http://dx.doi.org/10.2174/1871526518666180723152715DOI Listing
February 2020

Factors associated with menopausal age in Iranian women: Tehran Lipid and Glucose Study.

J Obstet Gynaecol Res 2013 Apr 21;39(4):836-41. Epub 2012 Dec 21.

Reproductive Endocrinology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Aim: Menopause, considered a special event in a woman's life, has a wide age range, 40-60 years, and there is no consensus regarding the factors influencing it. We aimed to assess factors affecting the menopausal age in a population of women participants of the Tehran Lipid and Glucose Study.

Material And Methods: For the present study, 1114 women were selected from among participants of the Tehran Lipid and Glucose Study. Following implementation of our inclusion criteria, their reproductive histories and demographic background as well as anthropometric parameters were assessed, and ordinal regression analysis was conducted using spss version 15.

Results: The mean estimated age at menopause ± standard deviation was 49.6 ± 4.5 years. Menopausal age was considerably lower among women with a history of smoking (P = 0.05), and it increased with increasing age of menarche (P = 0.04) and number of children (P = 0.05). There was no significant correlation between the mean age of menopause and the educational level and anthropometric parameters.

Conclusion: The smoking status, parity and the age of menarche are the influencing factors of age at menopause among the Iranian population.
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http://dx.doi.org/10.1111/j.1447-0756.2012.02050.xDOI Listing
April 2013