Masayuki Yamamoto

Masayuki Yamamoto

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Masayuki Yamamoto

Publications by authors named "Masayuki Yamamoto"

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Cis-element architecture of Nrf2-sMaf heterodimer binding sites and its relation to diseases.

Arch Pharm Res 2020 Mar 2;43(3):275-285. Epub 2019 Dec 2.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine and Tohoku University Tohoku Medical Megabank Organization, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.

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http://dx.doi.org/10.1007/s12272-019-01193-2DOI Listing
March 2020

Further characterization of the synergistic activation mechanism of cationic channels by M and M muscarinic receptors in mouse intestinal smooth muscle cells.

Am J Physiol Cell Physiol 2020 Mar 25;318(3):C514-C523. Epub 2019 Dec 25.

Laboratory of Veterinary Pharmacology, Department of Veterinary Medicine, Faculty of Applied Biological Science, Gifu University, Gifu, Japan.

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http://dx.doi.org/10.1152/ajpcell.00277.2019DOI Listing
March 2020

deletion accelerates mutant /-driven cholangiocarcinoma.

Am J Physiol Gastrointest Liver Physiol 2020 Mar 21;318(3):G419-G427. Epub 2020 Jan 21.

Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1152/ajpgi.00296.2019DOI Listing
March 2020

Amino-acid selective isotope labeling enables simultaneous overlapping signal decomposition and information extraction from NMR spectra.

J Biomol NMR 2020 Mar 30;74(2-3):125-137. Epub 2020 Jan 30.

Laboratory for Cellular Structural Biology, RIKEN Center for Biosystems Dynamics Research, Yokohama, Japan.

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http://dx.doi.org/10.1007/s10858-019-00295-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080692PMC
March 2020

Impacts of NRF2 activation in non-small-cell lung cancer cell lines on extracellular metabolites.

Cancer Sci 2020 Feb 15;111(2):667-678. Epub 2020 Jan 15.

Department of Integrative Genomics, Tohoku University Tohoku Medical Megabank Organization, Sendai, Japan.

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http://dx.doi.org/10.1111/cas.14278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004536PMC
February 2020

Nrf2 Suppresses Oxidative Stress and Inflammation in Knock-In Alzheimer's Disease Model Mice.

Mol Cell Biol 2020 Feb 27;40(6). Epub 2020 Feb 27.

Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Miyagi, Japan

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http://dx.doi.org/10.1128/MCB.00467-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048263PMC
February 2020

Meiotic gene silencing complex MTREC/NURS recruits the nuclear exosome to YTH-RNA-binding protein Mmi1.

PLoS Genet 2020 Feb 3;16(2):e1008598. Epub 2020 Feb 3.

Laboratory of Cell Responses, National Institute for Basic Biology, Myodaiji, Okazaki, Aichi, Japan.

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http://dx.doi.org/10.1371/journal.pgen.1008598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018101PMC
February 2020

Wavelength- and Tissue-dependent Variations in the Mutagenicity of Cyclobutane Pyrimidine Dimers in Mouse Skin.

Photochem Photobiol 2020 01 15;96(1):94-104. Epub 2019 Oct 15.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1111/php.13159DOI Listing
January 2020

Quantitative and qualitative impairments in GATA2 and myeloid neoplasms.

IUBMB Life 2020 01 1;72(1):142-150. Epub 2019 Nov 1.

Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.

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http://dx.doi.org/10.1002/iub.2188DOI Listing
January 2020

Two effects of GATA2 enhancer repositioning by 3q chromosomal rearrangements.

IUBMB Life 2020 01 9;72(1):159-169. Epub 2019 Dec 9.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1002/iub.2191DOI Listing
January 2020

Study profile of The Tohoku Medical Megabank Community-Based Cohort Study.

J Epidemiol 2020 Jan 11. Epub 2020 Jan 11.

Tohoku Medical Megabank Organization, Tohoku University.

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http://dx.doi.org/10.2188/jea.JE20190271DOI Listing
January 2020

Oxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromate.

Mutat Res 2020 Feb - Mar;850-851:503136. Epub 2020 Jan 15.

National Institute of Health Sciences, Division of Genetics and Mutagenesis, Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa 210-9501, Japan.

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http://dx.doi.org/10.1016/j.mrgentox.2020.503136DOI Listing
January 2020

Role of Nrf2 in inflammatory response in lung of mice exposed to zinc oxide nanoparticles.

Part Fibre Toxicol 2019 12 16;16(1):47. Epub 2019 Dec 16.

Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://dx.doi.org/10.1186/s12989-019-0328-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6915997PMC
December 2019

[A Case of Successful Surgical Treatment for Paraaortic Lymph Nodes Recurrence of Gallbladder Cancer].

Gan To Kagaku Ryoho 2019 Dec;46(13):2261-2263

Dept. of Surgery and Gastrointestinal Surgery, Itami City Hospital.

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December 2019

GATA2 and PU.1 Collaborate To Activate the Expression of the Mouse Gene, Encoding FcεRIβ, through Distinct Mechanisms.

Mol Cell Biol 2019 11 28;39(22). Epub 2019 Oct 28.

Department of Pharmacy, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Japan

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http://dx.doi.org/10.1128/MCB.00314-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6817753PMC
November 2019

Aryl Hydrocarbon Receptor Directly Regulates Gene Expression.

Mol Cell Biol 2019 10 27;39(20). Epub 2019 Sep 27.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Aoba, Sendai, Japan

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http://dx.doi.org/10.1128/MCB.00190-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766698PMC
October 2019

Direct and Specific Functional Evaluation of the Nrf2 and MafG Heterodimer by Introducing a Tethered Dimer into Small Maf-Deficient Cells.

Mol Cell Biol 2019 10 27;39(20). Epub 2019 Sep 27.

Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan

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http://dx.doi.org/10.1128/MCB.00273-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766697PMC
October 2019

Dietary supplementation with sulforaphane attenuates liver damage and heme overload in a sickle cell disease murine model.

Exp Hematol 2019 09 9;77:51-60.e1. Epub 2019 Aug 9.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan; Tohoku Medical Mega-Bank Organization, Tohoku University, Sendai, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.exphem.2019.08.001DOI Listing
September 2019

Mouse Tryptase Gene Expression is Coordinately Regulated by GATA1 and GATA2 in Bone Marrow-Derived Mast Cells.

Int J Mol Sci 2019 Sep 17;20(18). Epub 2019 Sep 17.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai 980-8573, Japan.

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http://dx.doi.org/10.3390/ijms20184603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770354PMC
September 2019

Outlier detection for questionnaire data in biobanks.

Int J Epidemiol 2019 08;48(4):1305-1315

Statistical Genetics Team, RIKEN Center for Advanced Intelligence Project, Tokyo, Japan.

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http://dx.doi.org/10.1093/ije/dyz012DOI Listing
August 2019

Spiral ganglion cell degeneration-induced deafness as a consequence of reduced GATA factor activity.

Genes Cells 2019 Aug 4;24(8):534-545. Epub 2019 Jul 4.

Division of Medical Biochemistry, Tohoku Medical Pharmaceutical University, Sendai, Japan.

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http://dx.doi.org/10.1111/gtc.12705DOI Listing
August 2019

Conductive Adhesive Film Expands the Utility of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging.

Anal Chem 2019 07 28;91(14):8979-8986. Epub 2019 Jun 28.

School of Dental Medicine , Tsurumi University , 2-1-3 Tsurumi , Tsurumi-ku, Yokohama , Kanagawa 230-8501 , Japan.

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http://dx.doi.org/10.1021/acs.analchem.9b01159DOI Listing
July 2019

Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap1.

Cell Rep 2019 07;28(3):746-758.e4

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8575, Japan; Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai 980-8573, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.06.047DOI Listing
July 2019

A Case Where Selective Plasma Exchange for Neuromyelitis Optica Was Effective.

Ther Apher Dial 2019 Jun;23(3):299-300

Clinical Engineering Center, Nishichita General Hospital, Aichi, Japan.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1744-9987.12
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http://dx.doi.org/10.1111/1744-9987.12817DOI Listing
June 2019

Environmental Electrophile-Mediated Toxicity in Mice Lacking Nrf2, CSE, or Both.

Environ Health Perspect 2019 06 5;127(6):67002. Epub 2019 Jun 5.

1 Environmental Biology Laboratory, Faculty of Medicine, University of Tsukuba , Tsukuba, Japan.

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http://dx.doi.org/10.1289/EHP4949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794492PMC
June 2019

Respiratory resistance among adults in a population-based cohort study in Northern Japan.

Respir Investig 2019 May 13;57(3):274-281. Epub 2019 Feb 13.

Department of Occupational Health, Tohoku University Graduate School of Medicine, Japan; Tohoku University Tohoku Medical Megabank Organization, Japan; Center for Environmental Conservation and Research Safety, Tohoku University, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.resinv.2018.12.008DOI Listing
May 2019

Structural instability of IκB kinase β promotes autophagic degradation through enhancement of Keap1 binding.

PLoS One 2018 30;13(11):e0203978. Epub 2018 Nov 30.

Department of Molecular Medical Science, Graduate School of Biomedical Science, Hiroshima University, Hiroshima, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203978PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267955PMC
April 2019

GATA2 hypomorphism induces chronic myelomonocytic leukemia in mice.

Cancer Sci 2019 Apr 23;110(4):1183-1193. Epub 2019 Feb 23.

Department of Molecular Hematology, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://doi.wiley.com/10.1111/cas.13959
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http://dx.doi.org/10.1111/cas.13959DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447832PMC
April 2019

Identification of genetic alterations in extramammary Paget disease using whole exome analysis.

J Dermatol Sci 2019 Apr 11;94(1):229-235. Epub 2019 Apr 11.

Department of Dermatology, Shinshu University School of Medicine, Asahi 3-1-1, Matsumoto, 390-8621 Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09231811193007
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http://dx.doi.org/10.1016/j.jdermsci.2019.03.006DOI Listing
April 2019

Nrf2 Suppresses Allergic Lung Inflammation by Attenuating the Type 2 Innate Lymphoid Cell Response.

J Immunol 2019 03 23;202(5):1331-1339. Epub 2019 Jan 23.

Division of Cancer Biology and Therapeutics, Miyagi Cancer Center Research Institute, Medeshima-Shiode, Natori 981-1293, Japan;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1801180
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http://dx.doi.org/10.4049/jimmunol.1801180DOI Listing
March 2019

New insights into nuclear factor erythroid 2-related factors in toxicology and pharmacology.

Toxicol Appl Pharmacol 2019 03 4;367:33-35. Epub 2019 Feb 4.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2019.01.014DOI Listing
March 2019

Nrf2 deficiency aggravates the increase in osteoclastogenesis and bone loss induced by inorganic arsenic.

Toxicol Appl Pharmacol 2019 03 8;367:62-70. Epub 2019 Feb 8.

School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang 110122, China. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2019.02.003DOI Listing
March 2019

Nrf2 Activation Ameliorates Hepatotoxicity Induced by a Heme Synthesis Inhibitor.

Toxicol Sci 2019 01;167(1):227-238

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Aoba, Sendai 980-8575, Japan.

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http://dx.doi.org/10.1093/toxsci/kfy233DOI Listing
January 2019

Nrf2 represses the onset of type 1 diabetes in non-obese diabetic mice.

J Endocrinol 2019 Jan 1. Epub 2019 Jan 1.

M Yamamoto, Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.

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https://joe.bioscientifica.com/view/journals/joe/aop/joe-18-
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http://dx.doi.org/10.1530/JOE-18-0355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602871PMC
January 2019

Roles of the KEAP1-NRF2 system in mammalian skin exposed to UV radiation.

Toxicol Appl Pharmacol 2018 12 28;360:69-77. Epub 2018 Sep 28.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1016/j.taap.2018.09.038DOI Listing
December 2018

Development and application of a rapid and sensitive genotyping method for pharmacogene variants using the single-stranded tag hybridization chromatographic printed-array strip (STH-PAS).

Drug Metab Pharmacokinet 2018 Dec 22;33(6):258-263. Epub 2018 Aug 22.

Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba Aramaki, Aoba-ku, Sendai, 980-8578, Japan; Advanced Research Center for Innovations in Next-Generation Medicine, Tohoku University, Sendai, 980-8575, Japan; Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8573, Japan; Department of Pharmaceutical Sciences, Tohoku University Hospital, 1-1 Seiryo-machi, Aoba-ku, Sendai, 980-8574, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.dmpk.2018.08.003DOI Listing
December 2018

Sulforaphane ameliorates steroid insensitivity through an Nrf2-dependent pathway in cigarette smoke-exposed asthmatic mice.

Free Radic Biol Med 2018 12 9;129:473-485. Epub 2018 Oct 9.

Department of Pulmonary Medicine, Division of Clinical Medicine, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S08915849183175
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http://dx.doi.org/10.1016/j.freeradbiomed.2018.10.400DOI Listing
December 2018

Tumors sweeten macrophages with acids.

Nat Immunol 2018 12;19(12):1281-1283

Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.

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http://www.nature.com/articles/s41590-018-0258-0
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http://dx.doi.org/10.1038/s41590-018-0258-0DOI Listing
December 2018

Formation of a Methylenedioxy Bridge in (+)-Epipinoresinol by CYP81Q3 Corroborates with Diastereomeric Specialization in Sesame Lignans.

Plant Cell Physiol 2018 Nov;59(11):2278-2287

Suntory Foundation for Life Sciences, 8-1-1 Seikadai, Seika, Soraku, Kyoto, Japan.

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http://dx.doi.org/10.1093/pcp/pcy150DOI Listing
November 2018

A 3' Distal Otic Vesicle Enhancer Directs Inner Ear-Specific Expression.

Mol Cell Biol 2018 11 15;38(21). Epub 2018 Oct 15.

Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan, USA

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http://dx.doi.org/10.1128/MCB.00302-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189460PMC
November 2018

NRF2 mitigates acute alcohol-induced hepatic and pancreatic injury in mice.

Food Chem Toxicol 2018 Nov 21;121:495-503. Epub 2018 Sep 21.

Program of Environmental Toxicology, School of Public Health, China Medical University, No. 77 Puhe Road, Shenyang North New Area, Shenyang, Liaoning, 110122, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2018.09.042DOI Listing
November 2018

Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

Nat Commun 2018 11 28;9(1):5052. Epub 2018 Nov 28.

Medical Genomics Center, National Center for Global Health and Medicine, Tokyo, 162-8655, Japan.

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http://dx.doi.org/10.1038/s41467-018-07345-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261994PMC
November 2018

Severity of eczema and mental health problems in Japanese schoolchildren: The ToMMo Child Health Study.

Allergol Int 2018 Oct 13;67(4):481-486. Epub 2018 Apr 13.

Department of Disaster Public Health, International Research Institute of Disaster Science, Tohoku University, Sendai, Japan; Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan; Department of Molecular Epidemiology, Graduate School of Medicine, Tohoku University, Sendai, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S13238930183001
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http://dx.doi.org/10.1016/j.alit.2018.02.009DOI Listing
October 2018

Functional characterization of 40 CYP2B6 allelic variants by assessing efavirenz 8-hydroxylation.

Biochem Pharmacol 2018 10 8;156:420-430. Epub 2018 Sep 8.

Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-8578, Japan; Advanced Research Center for Innovations in Next-Generation Medicine, Tohoku University, Sendai 980-8575, Japan; Tohoku Medical Megabank Organization, Tohoku University, Sendai 980-8575, Japan; Department of Pharmaceutical Sciences, Tohoku University Hospital, Sendai 980-8574, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00062952183039
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http://dx.doi.org/10.1016/j.bcp.2018.09.010DOI Listing
October 2018

Phenethyl Isothiocyanate, a Dual Activator of Transcription Factors NRF2 and HSF1.

Mol Nutr Food Res 2018 09 19;62(18):e1700908. Epub 2018 Jun 19.

Cullman Chemoprotection Center, Johns Hopkins University, Baltimore, MD, 21205, USA.

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http://doi.wiley.com/10.1002/mnfr.201700908
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http://dx.doi.org/10.1002/mnfr.201700908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175120PMC
September 2018

Genetic inactivation of Nrf2 prevents clonal expansion of initiated cells in a nutritional model of rat hepatocarcinogenesis.

J Hepatol 2018 09 22;69(3):635-643. Epub 2018 Jun 22.

Department of Biomedical Sciences, School of Medicine, University of Cagliari, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2018.05.010DOI Listing
September 2018

Palmitate deranges erythropoietin production via transcription factor ATF4 activation of unfolded protein response.

Kidney Int 2018 09 7;94(3):536-550. Epub 2018 Jun 7.

Division of CKD Pathophysiology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2018.03.011DOI Listing
September 2018

Adipocyte-specific deficiency of Nfe2l1 disrupts plasticity of white adipose tissues and metabolic homeostasis in mice.

Biochem Biophys Res Commun 2018 09 25;503(1):264-270. Epub 2018 Jun 25.

School of Public Health, China Medical University, Shenyang, 110122, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2018.06.013DOI Listing
September 2018

-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF1.

Mol Cell Biol 2018 09 15;38(17). Epub 2018 Aug 15.

Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan

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http://dx.doi.org/10.1128/MCB.00252-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094050PMC
September 2018

Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy.

Redox Biol 2018 09 11;18:173-180. Epub 2018 Jul 11.

Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), ISCIII. Instituto de Investigaciones Biomédicas "Alberto Sols", UAM-CSIC. Instituto de Investigación Sanitaria La Paz (IdiPaz) and Department of Biochemistry, Faculty of Medicine, Autonomous University of MadridMadrid, Spain; Cellular and Molecular Medicine Department, Radiobiology Laboratory, "Victor Babes" National Institute of Pathology, Bucharest, Romania. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132317183041
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http://dx.doi.org/10.1016/j.redox.2018.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052199PMC
September 2018

Functional Characterization of 21 Allelic Variants of Dihydropyrimidine Dehydrogenase Identified in 1070 Japanese Individuals.

Drug Metab Dispos 2018 08 16;46(8):1083-1090. Epub 2018 May 16.

Laboratory of Pharmacotherapy of Life-Style Related Diseases, Graduate School of Pharmaceutical Sciences (E.H., Yo.N., F.A., Yu.N., N.H., M.H.), and Tohoku Medical Megabank Organization (S.S., J.Y., M.N., M.Y., M.H.), and Department of Pharmaceutical Sciences, Tohoku University Hospital, Sendai, Japan (M.M., H.Y., N.M., M.H.)

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http://dx.doi.org/10.1124/dmd.118.081737DOI Listing
August 2018

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis.

Physiol Rev 2018 07;98(3):1169-1203

Department of Medical Biochemistry, Graduate School of Medicine, Tohoku University , Sendai , Japan ; Department of Pharmacology & Chemical Biology, University of Pittsburgh , Pittsburgh, Pennsylvania ; and Department of Gene Expression Regulation, Institute of Development, Aging and Cancer, Tohoku University , Sendai , Japan.

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http://dx.doi.org/10.1152/physrev.00023.2017DOI Listing
July 2018

Macrophages Switch Their Phenotype by Regulating Maf Expression during Different Phases of Inflammation.

J Immunol 2018 07 15;201(2):635-651. Epub 2018 Jun 15.

Laboratory of Immune Regulation, The School of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan;

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http://dx.doi.org/10.4049/jimmunol.1800040DOI Listing
July 2018

Detection of novel metabolite for roxadustat doping by global metabolomics.

J Biochem 2018 06;163(6):e1

Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8573, Japan.

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https://academic.oup.com/jb/article/163/6/e1/4996379
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http://dx.doi.org/10.1093/jb/mvy036DOI Listing
June 2018

Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo.

Genes Cells 2018 May 15;23(5):386-392. Epub 2018 Mar 15.

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://doi.wiley.com/10.1111/gtc.12579
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http://dx.doi.org/10.1111/gtc.12579DOI Listing
May 2018

Quantitative analysis of UV photolesions suggests that cyclobutane pyrimidine dimers produced in mouse skin by UVB are more mutagenic than those produced by UVC.

Photochem Photobiol Sci 2018 Apr;17(4):404-413

Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://xlink.rsc.org/?DOI=C7PP00348J
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http://dx.doi.org/10.1039/c7pp00348jDOI Listing
April 2018

Nrf2 activation attenuates genetic endoplasmic reticulum stress induced by a mutation in the phosphomannomutase 2 gene in zebrafish.

Proc Natl Acad Sci U S A 2018 03 22;115(11):2758-2763. Epub 2018 Feb 22.

Department of Molecular and Developmental Biology, Faculty of Medicine, University of Tsukuba, 305-8575 Tsukuba, Japan;

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http://dx.doi.org/10.1073/pnas.1714056115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856520PMC
March 2018

YTH-RNA-binding protein prevents deleterious expression of meiotic proteins by tethering their mRNAs to nuclear foci.

Elife 2018 02 9;7. Epub 2018 Feb 9.

Laboratory of Cell Responses, National Institute for Basic Biology, Okazaki, Japan.

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http://dx.doi.org/10.7554/eLife.32155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807050PMC
February 2018

Detection of novel metabolite for Roxadustat doping by global metabolomics.

J Biochem 2018 Feb 9. Epub 2018 Feb 9.

Department of Integrative Genomics, Tohoku Medical Megabank Organization, Tohoku University, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8573, Japan.

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https://academic.oup.com/jb/advance-article/doi/10.1093/jb/m
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http://dx.doi.org/10.1093/jb/mvy028DOI Listing
February 2018

[CNC-small Maf heterodimer: Unique cis-element recognition and biological functions].

Seikagaku 2017 Apr;89(2):278-81

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April 2017