Masayuki Amano

Masayuki Amano

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Masayuki Amano

Masayuki Amano

Publications by authors named "Masayuki Amano"

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48Publications

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Amino-acid inserts of HIV-1 capsid (CA) induce CA degradation and abrogate viral infectivity: Insights for the dynamics and mechanisms of HIV-1 CA decomposition.

Sci Rep 2019 Jul 8;9(1):9806. Epub 2019 Jul 8.

Department of Hematology, Rheumatology, and Infectious Diseases, Kumamoto University School of Medicine, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1038/s41598-019-46082-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614453PMC
July 2019

Mondor's Disease: A Review of the Literature.

Intern Med 2018 Sep 18;57(18):2607-2612. Epub 2018 May 18.

Department of Diagnostic and Generalist Medicine, Dokkyo Medical University Hospital, Japan.

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http://dx.doi.org/10.2169/internalmedicine.0495-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191595PMC
September 2018

Design, Synthesis, Biological Evaluation, and X-ray Studies of HIV-1 Protease Inhibitors with Modified P2' Ligands of Darunavir.

ChemMedChem 2017 12 24;12(23):1942-1952. Epub 2017 Nov 24.

Departments of Hematology and Infectious Diseases, Kumamoto University School of Medicine, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1002/cmdc.201700614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896574PMC
December 2017

Design, synthesis, X-ray studies, and biological evaluation of novel macrocyclic HIV-1 protease inhibitors involving the P1'-P2' ligands.

Bioorg Med Chem Lett 2017 11 6;27(21):4925-4931. Epub 2017 Sep 6.

Departments of Hematology and Infectious Diseases, Kumamoto University of Medicine, Kumamoto 860-8556, Japan; Experimental Retrovirology Section, HIV and AIDS Malignancy Branch National Cancer Institute, Bethesda, MD 20892, USA; Center for Clinical Sciences, National Center for Global Health and Medicine, Shinjuku, Tokyo 162-8655, Japan.

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http://dx.doi.org/10.1016/j.bmcl.2017.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647257PMC
November 2017

Design of novel HIV-1 protease inhibitors incorporating isophthalamide-derived P2-P3 ligands: Synthesis, biological evaluation and X-ray structural studies of inhibitor-HIV-1 protease complex.

Bioorg Med Chem 2017 10 9;25(19):5114-5127. Epub 2017 Apr 9.

Department of Hematology, Kumamoto University of Medicine, Kumamoto 860-8556, Japan; Department of Infectious Diseases, Kumamoto University of Medicine, Kumamoto 860-8556, Japan; Experimental Retrovirology Section, HIV and AIDS Malignancy Branch National Cancer Institute, Bethesda, MD 20892, USA; Department of Refractory Viral Infection, National Center for Global Health and Medicine Research Institute, Shinjuku, Tokyo 162-8655, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S09680896173073
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http://dx.doi.org/10.1016/j.bmc.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617771PMC
October 2017

Immunomodulatory drugs act as inhibitors of DNA methyltransferases and induce PU.1 up-regulation in myeloma cells.

Biochem Biophys Res Commun 2016 Jan 30;469(2):236-42. Epub 2015 Nov 30.

Departments of Hematology, Rheumatology, and Infectious Disease, Kumamoto University Graduate School of Medicine, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.11.116DOI Listing
January 2016

Structure-based design, synthesis, X-ray studies, and biological evaluation of novel HIV-1 protease inhibitors containing isophthalamide-derived P2-ligands.

Bioorg Med Chem Lett 2015 Nov 30;25(21):4903-4909. Epub 2015 May 30.

Departments of Hematology and Infectious Diseases, Kumamoto University of Medicine, Kumamoto 860-8556, Japan; Experimental Retrovirology Section, HIV and AIDS Malignancy Branch, National Cancer Institute, Bethesda, MD 20892, USA; Center for Clinical Sciences, National Center for Global Health and Medicine, Shinjuku, Tokyo 162-8655, Japan.

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http://dx.doi.org/10.1016/j.bmcl.2015.05.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607586PMC
November 2015

Structure-based design of potent HIV-1 protease inhibitors with modified P1-biphenyl ligands: synthesis, biological evaluation, and enzyme-inhibitor X-ray structural studies.

J Med Chem 2015 Jul 24;58(13):5334-43. Epub 2015 Jun 24.

§Departments of Hematology and Infectious Diseases, Kumamoto University Graduate School of Medical and Pharmaceutical Sciences, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1021/acs.jmedchem.5b00676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765733PMC
July 2015

A novel tricyclic ligand-containing nonpeptidic HIV-1 protease inhibitor, GRL-0739, effectively inhibits the replication of multidrug-resistant HIV-1 variants and has a desirable central nervous system penetration property in vitro.

Antimicrob Agents Chemother 2015 May 17;59(5):2625-35. Epub 2015 Feb 17.

Departments of Infectious Diseases and Hematology, Kumamoto University School of Medicine, Kumamoto, Japan Experimental Retrovirology Section, HIV and AIDS Malignancy Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan

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http://dx.doi.org/10.1128/AAC.04757-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394833PMC
May 2015

Emphysematous cystitis: a review of the literature.

Intern Med 2014 1;53(2):79-82. Epub 2012 Mar 1.

Nara Prefectural Nara Hospital, Japan.

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http://dx.doi.org/10.2169/internalmedicine.53.1121DOI Listing
September 2014

Design and synthesis of potent macrocyclic HIV-1 protease inhibitors involving P1-P2 ligands.

Org Biomol Chem 2014 Sep;12(35):6842-54

Departments of Chemistry and Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, USA.

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http://dx.doi.org/10.1039/c4ob00738gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4133278PMC
September 2014

Highly potent HIV-1 protease inhibitors with novel tricyclic P2 ligands: design, synthesis, and protein-ligand X-ray studies.

J Med Chem 2013 Sep 15;56(17):6792-802. Epub 2013 Aug 15.

Department of Chemistry and Department of Medicinal Chemistry, Purdue University , West Lafayette, Indiana 47907, United States.

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http://dx.doi.org/10.1021/jm400768fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800042PMC
September 2013

[Recent and future development of anti-HIV agents].

Nihon Rinsho 2010 Mar;68(3):395-400

Department of Hematology, Kumamoto University Graduate School of Medicine.

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March 2010

Synthesis and biological evaluation of novel allophenylnorstatine-based HIV-1 protease inhibitors incorporating high affinity P2-ligands.

Bioorg Med Chem Lett 2010 Feb 5;20(3):1241-6. Epub 2009 Dec 5.

Departments of Chemistry and Medicinal Chemistry, Purdue University, West Lafayette, IN 47907, United States.

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http://dx.doi.org/10.1016/j.bmcl.2009.11.123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179850PMC
February 2010

Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization.

J Biol Chem 2007 Sep 17;282(39):28709-20. Epub 2007 Jul 17.

Department of Hematology, Kumamoto University Graduate School of Medical and Pharmaceutical Sciences, 1-1-1 Honjo, Kumamoto 860-8556, Japan.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M703938200
Publisher Site
http://dx.doi.org/10.1074/jbc.M703938200DOI Listing
September 2007

A novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI), GRL-98065, is potent against multiple-PI-resistant human immunodeficiency virus in vitro.

Antimicrob Agents Chemother 2007 Jun 19;51(6):2143-55. Epub 2007 Mar 19.

Departments of Infectious Diseases and Hematology, Kumamoto University School of Medicine, 1-1-1 Honjo, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1128/AAC.01413-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891396PMC
June 2007