Publications by authors named "Masatoshi Takagi"

100Publications

Copy Number Alteration Analysis for Neuroblastoma using Droplet Digital PCR.

Pediatr Int 2021 Jan 19. Epub 2021 Jan 19.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University (TMDU), Yushima 1-5-45, Bunkyo-Ku, Tokyo, 113-8519, Japan.

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January 2021

DNA Ligase IV Deficiency Identified by Chance Following Vaccine-Derived Rubella Virus Infection.

J Clin Immunol 2020 Nov 10;40(8):1187-1190. Epub 2020 Sep 10.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

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November 2020

VPS72/YL1-Mediated H2A.Z Deposition Is Required for Nuclear Reassembly after Mitosis.

Cells 2020 07 16;9(7). Epub 2020 Jul 16.

Institute of Biochemistry and Molecular Cell Biology, Medical School, RWTH Aachen University, 52074 Aachen, Germany.

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July 2020

Generation of an antibody recognizing a set of acetylated proteins, including subunits of BAF complexes.

Authors:
Masatoshi Takagi

Biochem Biophys Rep 2020 Jul 14;22:100720. Epub 2019 Dec 14.

Cellular Dynamics Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.

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July 2020

Inherited chromosomally integrated human herpesvirus-6 in a patient with XIAP deficiency.

Transpl Infect Dis 2020 Oct 8;22(5):e13331. Epub 2020 Jun 8.

Deprtment of Child Health and Development, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

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October 2020

Disseminated fusariosis in a child after haploidentical hematopoietic stem cell transplantation.

Pediatr Int 2020 Mar;62(3):419-420

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

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March 2020

Noncoding RNA transcription at enhancers and genome folding in cancer.

Cancer Sci 2019 Aug 10;110(8):2328-2336. Epub 2019 Jul 10.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan.

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August 2019

Identification of autoantibodies using human proteome microarrays in patients with IPEX syndrome.

Clin Immunol 2019 06 2;203:9-13. Epub 2019 Apr 2.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan. Electronic address:

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June 2019

Infantile-onset spinocerebellar ataxia type 5 associated with a novel SPTBN2 mutation: A case report.

Brain Dev 2019 Aug 18;41(7):630-633. Epub 2019 Mar 18.

Department of Pediatrics, Tokyo Medical and Dental University, Japan; Kawasaki North Center for Childhood Developmental Disorder, Japan.

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August 2019

[Primary immunodeficiencies and hematological malignancies].

Rinsho Ketsueki 2018;59(11):2459-2467

Department of Community Pediatrics, Perinatal and Maternal Medicine, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University.

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May 2019

Genetic analysis of undiagnosed ataxia-telangiectasia-like disorders.

Brain Dev 2019 Feb 6;41(2):150-157. Epub 2018 Oct 6.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address:

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February 2019

High frequencies of asymptomatic Epstein-Barr virus viremia in affected and unaffected individuals with CTLA4 mutations.

Clin Immunol 2018 10 24;195:45-48. Epub 2018 Jul 24.

Department of Child Health and Development, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan. Electronic address:

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October 2018

Status of KRAS in iPSCs Impacts upon Self-Renewal and Differentiation Propensity.

Stem Cell Reports 2018 08 5;11(2):380-394. Epub 2018 Jul 5.

Division of Stem Cell Processing/Stem Cell Bank, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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August 2018

Hematopoietic cell transplantation for myeloid/NK cell precursor acute leukemia in second remission.

Clin Case Rep 2018 Jun 10;6(6):1023-1028. Epub 2018 Apr 10.

Department of Pediatrics and Developmental Biology Graduate School of Medicine Tokyo Medical and Dental University Yushima 1-5-45, Bunkyo-ku Tokyo Japan.

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June 2018

Phenotype, penetrance, and treatment of 133 cytotoxic T-lymphocyte antigen 4-insufficient subjects.

J Allergy Clin Immunol 2018 12 4;142(6):1932-1946. Epub 2018 May 4.

Center for Chronic Immunodeficiency (CCI), Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Institute of Immunology and Transplantation, Royal Free Hospital, University College London, London, United Kingdom. Electronic address:

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December 2018

Droplet Digital PCR-Based Chimerism Analysis for Primary Immunodeficiency Diseases.

J Clin Immunol 2018 04 18;38(3):300-306. Epub 2018 Apr 18.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

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April 2018

Nationwide survey of therapy-related leukemia in childhood in Japan.

Int J Hematol 2018 Jul 24;108(1):91-97. Epub 2018 Mar 24.

Department of Pediatrics, Ehime Prefectural Central Hospital, Ehime, Japan.

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July 2018

Targeting the enhanced ER stress response in Marinesco-Sjögren syndrome.

J Neurol Sci 2018 02 9;385:49-56. Epub 2017 Dec 9.

Department of Pediatrics, Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address:

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February 2018

Haploinsufficiency of A20 causes autoinflammatory and autoimmune disorders.

J Allergy Clin Immunol 2018 04 11;141(4):1485-1488.e11. Epub 2017 Dec 11.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address:

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April 2018

Hematopoietic stem cell transplantation for pulmonary alveolar proteinosis associated with primary immunodeficiency disease.

Int J Hematol 2018 May 28;107(5):610-614. Epub 2017 Nov 28.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

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May 2018

Population Pharmacokinetics of Intravenous Busulfan in Japanese Pediatric Patients With Primary Immunodeficiency Diseases.

J Clin Pharmacol 2018 03 27;58(3):327-331. Epub 2017 Oct 27.

Department of Pharmacokinetics and Pharmacodynamics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.

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March 2018

Loss of DNA Damage Response in Neuroblastoma and Utility of a PARP Inhibitor.

J Natl Cancer Inst 2017 11;109(11)

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan; Department of Pediatrics, Graduate School of Medicine, Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, Laboratory of Sequence Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan; Department of Pediatrics and Adolescent Medicine, School of Medicine, Juntendo University, Tokyo, Japan; Department of Pediatric Hematology/Oncology, Saitama Children's Medical Center, Saitama, Japan, Department of Pediatrics, Nagara Medical Center, Gifu, Japan; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan; Division of Cancer Genomics, Saitama Cancer Center Research Institute, Saitama, Japan; Division of Cancer Genomics, Chiba Cancer Center, Chiba, Japan; Gunma Children's Medical Center, Gunma, Japan; Saga Medical Center, Saga, Japan.

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November 2017

Effect of reduced-intensity conditioning and the risk of late-onset non-infectious pulmonary complications in pediatric patients.

Eur J Haematol 2017 Dec 4;99(6):525-531. Epub 2017 Oct 4.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan.

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December 2017

Slowly progressive leukodystrophy in an adolescent male with phosphoglycerate kinase deficiency.

Brain Dev 2018 Feb 8;40(2):150-154. Epub 2017 Aug 8.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Bunkyo, Tokyo, Japan. Electronic address:

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February 2018

Erratum to: DNA damage response and hematological malignancy.

Authors:
Masatoshi Takagi

Int J Hematol 2017 09;106(3):450-453

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University (TMDU), Yushima 1-5-45, Bunkyo-ku, Tokyo, 113-8519, Japan.

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September 2017

Flow cytometry-based diagnosis of primary immunodeficiency diseases.

Allergol Int 2018 Jan 3;67(1):43-54. Epub 2017 Jul 3.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

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January 2018

Multicolor Flow Cytometry for the Diagnosis of Primary Immunodeficiency Diseases.

J Clin Immunol 2017 Jul 8;37(5):486-495. Epub 2017 Jun 8.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

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July 2017

DNA damage response and hematological malignancy.

Authors:
Masatoshi Takagi

Int J Hematol 2017 Sep 3;106(3):345-356. Epub 2017 Apr 3.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University (TMDU), Yushima 1-5-45, Bunkyo-ku, Tokyo, 113-8519, Japan.

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September 2017

A Stable Mixed Chimera After SCT with RIC in an Infant with IκBα Hypermorphic Mutation.

J Clin Immunol 2017 07 21;37(5):413-414. Epub 2017 Feb 21.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, 5-45 Yushima 1-chome, Bunkyo-ku, Tokyo, 113-8519, Japan.

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July 2017

Prolonged neutropenia due to antihuman neutrophil antigen 2 (CD177) antibody after bone marrow transplantation.

Pediatr Blood Cancer 2017 Jul 1;64(7). Epub 2016 Dec 1.

Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.

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July 2017

Poly (ADP-ribose) polymerase inhibitors selectively induce cytotoxicity in TCF3-HLF-positive leukemic cells.

Cancer Lett 2017 02 25;386:131-140. Epub 2016 Nov 25.

Department of Pediatrics and Developmental Biology, Graduate School of Medicine, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo, 113-8519, Japan. Electronic address:

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February 2017

Hematopoietic Stem Cell Transplantation for XIAP Deficiency in Japan.

J Clin Immunol 2017 01 4;37(1):85-91. Epub 2016 Nov 4.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

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January 2017

ELYS regulates the localization of LBR by modulating its phosphorylation state.

J Cell Sci 2016 11 6;129(22):4200-4212. Epub 2016 Oct 6.

Cellular Dynamics Laboratory, Riken, Saitama 351-0198, Japan

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November 2016

Antipsychotics promote neural differentiation of human iPS cell-derived neural stem cells.

Biochem Biophys Res Commun 2016 Nov 26;480(4):615-621. Epub 2016 Oct 26.

Department of Pharmacology, Graduate School of Medicine, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8602, Japan.

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November 2016

Ocular manifestation in myeloid/NK cell precursor acute leukemia: a case report. Diagnosed by flow cytometry and PCR from aqueous humor.

Medicine (Baltimore) 2016 Sep;95(38):e4967

Department of Ophthalmology & Visual Science, Graduate School of Medical and Dental Science Department of Pediatrics and Developmental Biology Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan Department of Radiation Therapeutics and Oncology, Tokyo Medical and Dental University, Tokyo, Japan.

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September 2016

EWSR1/ELF5 induces acute myeloid leukemia by inhibiting p53/p21 pathway.

Cancer Sci 2016 Dec 25;107(12):1745-1754. Epub 2016 Nov 25.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan.

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December 2016

Perichromosomal protein Ki67 supports mitotic chromosome architecture.

Genes Cells 2016 Oct 9;21(10):1113-1124. Epub 2016 Sep 9.

Cellular Dynamics Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama, 351-0198, Japan.

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October 2016

Inherited genetic variants associated with childhood acute lymphoblastic leukemia risk.

Rinsho Ketsueki 2016 07;57(7):891-9

Tokyo Medical and Dental University, Graduate School, Department of Pediatrics and Developmental Biology.

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July 2016

ATM and SIRT6/SNF2H Mediate Transient H2AX Stabilization When DSBs Form by Blocking HUWE1 to Allow Efficient γH2AX Foci Formation.

Cell Rep 2015 Dec 17;13(12):2728-40. Epub 2015 Dec 17.

Division of Carcinogenesis and Cancer Prevention, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan. Electronic address:

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December 2015

Dysregulation of the DNA Damage Response and KMT2A Rearrangement in Fetal Liver Hematopoietic Cells.

PLoS One 2015 11;10(12):e0144540. Epub 2015 Dec 11.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan.

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June 2016

Haploidentical Bone Marrow Transplantation With Clofarabine and Busulfan Conditioning for a Child With Multiple Recurrent Acute Lymphoblastic Leukemia.

J Pediatr Hematol Oncol 2016 Jan;38(1):e39-41

Departments of *Pediatrics ‡Transfusion Medicine §Pharmacy, Tokyo Medical and Dental University (TMDU) ∥Division of Leukemia and Lymphoma, Children's Cancer Center, National Center for Child Health and Development, Tokyo †Department of Pediatrics, Uwajima City Hospital, Uwajima, Japan.

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January 2016

[Genetics of hereditary hematological malignancies].

Authors:
Masatoshi Takagi

Rinsho Ketsueki 2015 Oct;56(10):1969-77

Department of Pediatrics and Developmental Biology, Graduate school, Tokyo Medical and Dental University.

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October 2015

Transient abnormal myelopoiesis in non-Down syndrome neonate.

Pediatr Int 2015 ;57(1):e14-7

Department of Pediatrics and Developmental Biology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.

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December 2016

ATM Regulates Adipocyte Differentiation and Contributes to Glucose Homeostasis.

Cell Rep 2015 Feb 12;10(6):957-967. Epub 2015 Feb 12.

Department of Pediatrics and Developmental Biology, Graduate School of Medicine, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan.

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February 2015

Graft versus host disease-dependent renal dysfunction after hematopoietic stem cell transplantation.

CEN Case Rep 2014 Nov 21;3(2):202-205. Epub 2014 Mar 21.

Department of Pediatrics, Graduate School, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, 113-8519, Japan.

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November 2014

A new microcolumn-type microchip for examining the expression of chimeric fusion genes using a nucleic acid sandwich hybridization technique.

J Chromatogr B Analyt Technol Biomed Life Sci 2014 Nov 6;970:60-7. Epub 2014 Sep 6.

R&D Div., Medical Business Unit, Sony Corporation, 5-1-12 Kitashinagawa, Shinagawa-ku, Tokyo 141-0001 Japan.

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November 2014

Hematopoietic myeloid cell differentiation diminishes nucleotide excision repair.

Int J Hematol 2014 Sep 16;100(3):260-5. Epub 2014 Jul 16.

Department of Pediatrics and Developmental Biology, Graduate Medical School, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo, 113-8519, Japan.

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September 2014

Ki67 antigen contributes to the timely accumulation of protein phosphatase 1γ on anaphase chromosomes.

J Biol Chem 2014 Aug 10;289(33):22877-87. Epub 2014 Jul 10.

From the Cellular Dynamics Laboratory, RIKEN, 2-1, Hirosawa, Wako, Saitama 351-0198, Japan

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August 2014

Whole-exome sequence analysis of ataxia telangiectasia-like phenotype.

J Neurol Sci 2014 May 4;340(1-2):86-90. Epub 2014 Mar 4.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address:

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May 2014

Control of nuclear size by NPC proteins.

Adv Exp Med Biol 2014 ;773:571-91

Cellular Dynamics Laboratory, RIKEN, WAKO, Saitama, 351-0198, Japan,

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September 2014

Notch2 activation ameliorates nephrosis.

Nat Commun 2014 ;5:3296

Division of Nephrology, Department of Internal Medicine, Juntendo University Faculty of Medicine, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan.

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November 2015

FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice.

FASEB J 2014 May 22;28(5):2020-8. Epub 2014 Jan 22.

1Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Bunkyo, Tokyo 113-8510, Japan.

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May 2014

Two novel HSD3B2 missense mutations with diverse residual enzymatic activities for Δ5-steroids.

Clin Endocrinol (Oxf) 2014 Jun 16;80(6):782-9. Epub 2014 Jan 16.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan.

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June 2014

ATM-dependent DNA damage-response pathway as a determinant in chronic myelogenous leukemia.

DNA Repair (Amst) 2013 Jul 19;12(7):500-7. Epub 2013 May 19.

Tokyo Medical and Dental University, Department of the Pediatrics and Developmental Biology, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan.

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July 2013

Artemis-dependent DNA double-strand break formation at stalled replication forks.

Cancer Sci 2013 Jun 15;104(6):703-10. Epub 2013 Apr 15.

Department of Pediatrics and Developmental Biology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.

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June 2013

XCIND as a genetic disease of X-irradiation hypersensitivity and cancer susceptibility.

Int J Hematol 2013 Jan 25;97(1):37-42. Epub 2012 Dec 25.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-Ku, Tokyo, Japan.

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January 2013

Ataxia telangiectasia mutated-dependent regulation of topoisomerase II alpha expression and sensitivity to topoisomerase II inhibitor.

Cancer Sci 2013 Feb 13;104(2):178-84. Epub 2013 Jan 13.

Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University, Tokyo, Japan.

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February 2013