Masanori Yoshizumi

Masanori Yoshizumi

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Masanori Yoshizumi

Masanori Yoshizumi

Publications by authors named "Masanori Yoshizumi"

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73Publications

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Proliferative Pathways of Vascular Smooth Muscle Cells in Response to Intermittent Hypoxia.

Int J Mol Sci 2019 Jun 1;20(11). Epub 2019 Jun 1.

Department of Pharmacology, Nara Medical University School of Medicine, Kashihara 634-8521, Japan.

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http://dx.doi.org/10.3390/ijms20112706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600262PMC
June 2019

[Vascular smooth muscle cell response to cyclic mechanical stretch and aortic dissection].

Nihon Yakurigaku Zasshi 2018;151(4):155-159

Department of Pharmacology, Nara Medical University School of Medicine.

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http://dx.doi.org/10.1254/fpj.151.155DOI Listing
March 2019

Chemokines protect vascular smooth muscle cells from cell death induced by cyclic mechanical stretch.

Sci Rep 2017 11 23;7(1):16128. Epub 2017 Nov 23.

Department of Pharmacology, Nara Medical University School of Medicine, Nara, Japan.

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http://dx.doi.org/10.1038/s41598-017-15867-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701048PMC
November 2017

Detection of Nitric Oxide Induced by Angiotensin II Receptor Type 1 Using Soluble Guanylate Cyclase beta1 Subunit Fused to a Yellow Fluorescent Protein, Venus.

J Fluoresc 2017 Jan 28;27(1):399-405. Epub 2016 Oct 28.

Department of Pharmacology, Nara Medical University School of Medicine, 840 Shijo-cho, Kashihara, Nara, 634-0813, Japan.

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http://dx.doi.org/10.1007/s10895-016-1968-zDOI Listing
January 2017

Angiotensin (1-7), small but complicated, needs more exercise.

Circ J 2015 15;79(6):1220-1. Epub 2015 May 15.

Department of Cardiovascular Physiology and Medicine, Graduate School of Biomedical and Health Sciences Hiroshima University.

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http://dx.doi.org/10.1253/circj.CJ-15-0448DOI Listing
March 2016

Olmesartan inhibits cultured rat aortic smooth muscle cell death induced by cyclic mechanical stretch through the inhibition of the c-Jun N-terminal kinase and p38 signaling pathways.

J Pharmacol Sci 2015 Jan 15;127(1):69-74. Epub 2014 Nov 15.

Department of Pharmacology, Nara Medical University School of Medicine, Kashihara, Nara, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jphs.2014.11.002DOI Listing
January 2015

Intermittent hypoxia induces the proliferation of rat vascular smooth muscle cell with the increases in epidermal growth factor family and erbB2 receptor.

Exp Cell Res 2013 Nov 19;319(19):3042-50. Epub 2013 Aug 19.

Department of Pharmacology, Nara Medical University School of Medicine, Kashihara 634-8521, Japan; Department of Pharmacy, Nara Medical University Hospital, Kashihara 634-8522, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2013.08.014DOI Listing
November 2013

Role of big mitogen-activated protein kinase 1 (BMK1) / extracellular signal-regulated kinase 5 (ERK5) in the pathogenesis and progression of atherosclerosis.

J Pharmacol Sci 2012 20;120(4):259-63. Epub 2012 Nov 20.

Department of Pharmacology, Nara Medical University School of Medicine, Kashihara, Nara 634-8521, Japan.

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http://dx.doi.org/10.1254/jphs.12r11cpDOI Listing
June 2013

Proteomic analysis of S-nitrosylation induced by 1-methyl-4-phenylpyridinium (MPP+).

Proteome Sci 2012 Dec 29;10(1):74. Epub 2012 Dec 29.

Department of Pharmacology, Nara Medical University School of Medicine, 840 Shijo-cho, Kashihara, Nar, 634-8521, Japan.

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http://dx.doi.org/10.1186/1477-5956-10-74DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576269PMC
December 2012

Prevention of the wortmannin-induced inhibition of phosphoinositide 3-kinase by sulfhydryl reducing agents.

Pharmacol Rep 2011 ;63(3):733-9

Department of Pharmacology, Nara Medical University, Kashihara, Nara 634 8521, Japan.

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http://dx.doi.org/10.1016/s1734-1140(11)70585-0DOI Listing
December 2011

Big mitogen-activated protein kinase 1 protects cultured rat aortic smooth muscle cells from oxidative damage.

J Pharmacol Sci 2011 19;116(2):173-80. Epub 2011 May 19.

Department of Pharmacology, Nara Medical University School of Medicine, Japan.

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http://dx.doi.org/10.1254/jphs.11015fpDOI Listing
October 2011

Pharmacology in health food: metabolism of quercetin in vivo and its protective effect against arteriosclerosis.

J Pharmacol Sci 2011 24;115(4):466-70. Epub 2011 Mar 24.

Department of Medical Pharmacology, Institute of Health Bioscience, The University of Tokushima Graduate School, Japan.

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http://dx.doi.org/10.1254/jphs.10r38fmDOI Listing
August 2011

Pharmacology in health foods: preface.

J Pharmacol Sci 2011 24;115(4):459-60. Epub 2011 Mar 24.

Department of Pharmacology, Nara Medical University, School of Medicine, Japan.

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http://dx.doi.org/10.1254/jphs.10r35fmDOI Listing
August 2011

Functional restoration of endothelial cells of the cryopreserved heart valve.

Gen Thorac Cardiovasc Surg 2011 Mar 30;59(3):169-74. Epub 2011 Mar 30.

Department of Cardiovascular Surgery, The University of Tokushima Graduate School of Health Biosciences, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan.

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http://link.springer.com/10.1007/s11748-010-0711-y
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http://dx.doi.org/10.1007/s11748-010-0711-yDOI Listing
March 2011

Olmesartan inhibits angiotensin II-Induced migration of vascular smooth muscle cells through Src and mitogen-activated protein kinase pathways.

J Pharmacol Sci 2010 28;113(2):161-8. Epub 2010 May 28.

Department of Pharmacology, Nara Medical University School of Medicine, Nara, Japan.

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http://dx.doi.org/10.1254/jphs.09332fpDOI Listing
September 2010

Neuroprotective effects of pramipexole against tunicamycin-induced cell death in PC12 cells.

Clin Exp Pharmacol Physiol 2009 Dec 9;36(12):1183-5. Epub 2009 Jun 9.

Department of Pharmacology, Nara Medical University School of Medicine, Kashihara, Nara, Japan.

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http://dx.doi.org/10.1111/j.1440-1681.2009.05224.xDOI Listing
December 2009

[Evidence based medicine in dietary supplements].

Nihon Yakurigaku Zasshi 2009 May;133(5):297

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May 2009

ER stress is the initial response to polyglutamine toxicity in PC12 cells.

Biochem Biophys Res Commun 2008 Dec 12;377(2):550-555. Epub 2008 Oct 12.

Laboratory of Neurobiology, Department of Life Science and Biotechnology, Faculty of Chemistry, Materials and Bioengineering and High Technology Research Center (HRC), Kansai University, Suita, Osaka 564-8680, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2008.10.006DOI Listing
December 2008

Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells.

Biochem Biophys Res Commun 2008 May 19;370(1):159-63. Epub 2008 Mar 19.

Aab Cardiovascular Research Institute and Department of Medicine, University of Rochester School of Medicine and Dentistry, Box 706, 601 Elmwood Avenue, Rochester, NY 14642, USA.

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http://dx.doi.org/10.1016/j.bbrc.2008.03.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2435412PMC
May 2008

The novel Src kinase inhibitor M475271 inhibits VEGF-induced vascular endothelial-cadherin and beta-catenin phosphorylation but increases their association.

J Pharmacol Sci 2006 Sep 15;102(1):112-20. Epub 2006 Sep 15.

Department of Pharmacology, The University of Tokushima Graduate School, Institute of Health Biosciences, Japan.

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http://dx.doi.org/10.1254/jphs.fp0060357DOI Listing
September 2006

Transactivation of fetal liver kinase-1/kinase-insert domain-containing receptor by lysophosphatidylcholine induces vascular endothelial cell proliferation.

Endocrinology 2006 Mar 1;147(3):1377-85. Epub 2005 Dec 1.

Department of Pharmacology, The University of Tokushima Graduate School of Medical Sciences, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.

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http://dx.doi.org/10.1210/en.2005-0644DOI Listing
March 2006

Addition of the antioxidant probucol to angiotensin II type I receptor antagonist arrests progressive mesangioproliferative glomerulonephritis in the rat.

J Am Soc Nephrol 2006 Mar 8;17(3):783-94. Epub 2006 Feb 8.

Department of Pediatrics, The Institute of Health Bioscience, The University of Tokushima Graduate School, Kuramoto-cho-3-chome, Tokushima 770-8503, Japan.

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http://dx.doi.org/10.1681/ASN.2005050519DOI Listing
March 2006

Subtypes of neuronal nicotinic acetylcholine receptors involved in nicotine-induced phosphorylation of extracellular signal-regulated protein kinase in PC12h cells.

Neurosci Lett 2006 Jan 10;392(1-2):101-4. Epub 2005 Oct 10.

Department of Pharmacology, Nara Medical University School of Medicine, 840 Shijo-Chou, Kashihara, Japan.

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http://dx.doi.org/10.1016/j.neulet.2005.09.003DOI Listing
January 2006

Pramipexole protects against H2O2-induced PC12 cell death.

Naunyn Schmiedebergs Arch Pharmacol 2006 Jan 16;372(4):257-66. Epub 2005 Dec 16.

Department of Pharmacology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima, 770-8503, Japan.

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http://link.springer.com/content/pdf/10.1007/s00210-005-0025
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http://link.springer.com/10.1007/s00210-005-0025-2
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http://dx.doi.org/10.1007/s00210-005-0025-2DOI Listing
January 2006

ERK1/2 activation by angiotensin II inhibits insulin-induced glucose uptake in vascular smooth muscle cells.

Exp Cell Res 2005 Aug;308(2):291-9

Department of Pharmacology, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto 770-8503, Japan.

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http://dx.doi.org/10.1016/j.yexcr.2005.04.028DOI Listing
August 2005

A novel Src kinase inhibitor, M475271, inhibits VEGF-induced human umbilical vein endothelial cell proliferation and migration.

J Pharmacol Sci 2005 Jun 4;98(2):130-41. Epub 2005 Jun 4.

Department of Pharmacology, The University of Tokushima Graduate School Institute of Health Biosciences, Japan.

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http://dx.doi.org/10.1254/jphs.fp0040850DOI Listing
June 2005

Nitrite is an alternative source of NO in vivo.

Am J Physiol Heart Circ Physiol 2005 May 30;288(5):H2163-70. Epub 2004 Dec 30.

Department of Pharmacology, The University of Tokushima School of Medicine, Tokushima, Japan.

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http://dx.doi.org/10.1152/ajpheart.00525.2004DOI Listing
May 2005

Nitrite-derived nitric oxide formation following ischemia-reperfusion injury in kidney.

Am J Physiol Renal Physiol 2005 Jan 14;288(1):F182-7. Epub 2004 Sep 14.

Department of Pharmacology, University of Tokushima School of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.

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http://dx.doi.org/10.1152/ajprenal.00036.2004DOI Listing
January 2005

Malfunction of vascular control in lifestyle-related diseases: formation of systemic hemoglobin-nitric oxide complex (HbNO) from dietary nitrite.

J Pharmacol Sci 2004 Dec 10;96(4):395-400. Epub 2004 Dec 10.

Department of Clinical Pharmacology, Subdivision of Clinical Pharmaceutical Sciences, Institute of Health Biosciences, The University of Tokushima Graduate School, 1-78 Sho-machi, Tokushima 770-8505, Japan.

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http://dx.doi.org/10.1254/jphs.fmj04006x3DOI Listing
December 2004

[Endothelin in cardiac injury].

Nihon Rinsho 2004 Sep;62 Suppl 9:622-5

Department of Pharmacology, The University of Tokushima School of Medicine.

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September 2004

Atheroprotective effects of antioxidants through inhibition of mitogen-activated protein kinases.

Acta Pharmacol Sin 2004 Aug;25(8):977-85

Department of Pharmacology, The University of Tokushima Graduate School of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.

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August 2004

BMK1 is activated in glomeruli of diabetic rats and in mesangial cells by high glucose conditions.

Kidney Int 2004 May;65(5):1749-60

Department of Pharmacology and Pediatrics, The University of Tokushima School of Medicine, Tokushima, Japan.

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http://dx.doi.org/10.1111/j.1523-1755.2004.00576.xDOI Listing
May 2004

Ebselen inhibits p38 mitogen-activated protein kinase-mediated endothelial cell death by hydrogen peroxide.

Eur J Pharmacol 2004 Feb;485(1-3):127-35

Department of Pharmacology, The University of Tokushima School of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.

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http://dx.doi.org/10.1016/j.ejphar.2003.11.079DOI Listing
February 2004

The reaction rate of edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186)) with hydroxyl radical.

Chem Pharm Bull (Tokyo) 2004 Feb;52(2):186-91

Department of Pharmacology, The University of Tokushima School of Medicine, Tokushima, Japan.

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http://dx.doi.org/10.1248/cpb.52.186DOI Listing
February 2004

Enzymatic and nonenzymatic formation of reactive oxygen species from 6-anilino-5,8-quinolinequinone.

Biochim Biophys Acta 2004 Jan;1670(1):19-27

Department of Pharmacology, The University of Tokushima School of Medicine, 3-18-15 Kuramoto, 'Tokushima 770-8503, Japan.

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http://dx.doi.org/10.1016/j.bbagen.2003.10.008DOI Listing
January 2004

New methods to evaluate endothelial function: Evaluation of endothelial function by hemoglobin-nitric oxide complex using electron paramagnetic resonance spectroscopy.

J Pharmacol Sci 2003 Dec;93(4):417-22

Department of Pharmacology, The University of Tokushima School of Medicine, Kuramoto, Japan.

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http://dx.doi.org/10.1254/jphs.93.417DOI Listing
December 2003

Evaluation of systemic blood NO dynamics by EPR spectroscopy: HbNO as an endogenous index of NO.

Am J Physiol Heart Circ Physiol 2003 Aug 27;285(2):H589-96. Epub 2003 Mar 27.

Department of Pharmacology, The University of Tokushima School of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.

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http://dx.doi.org/10.1152/ajpheart.01010.2002DOI Listing
August 2003

Stress and vascular responses: atheroprotective effect of laminar fluid shear stress in endothelial cells: possible role of mitogen-activated protein kinases.

J Pharmacol Sci 2003 Mar;91(3):172-6

Department of Pharmacology, The University of Tokushima School of Medicine, Tokushima, Japan.

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http://dx.doi.org/10.1254/jphs.91.172DOI Listing
March 2003

Effect of endothelin-1 (1-31) on the renal resistance vessels.

J Med Invest 2003 Feb;50(1-2):87-94

Department of Pharmacolgy, The University of Tokushima School of Medicine, Tokushima, Japan.

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February 2003

The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation.

J Biol Chem 2002 Aug 14;277(32):29330-41. Epub 2002 May 14.

Center for Cardiovascular Research, University of Rochester, Rochester, New York 14642, USA.

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http://dx.doi.org/10.1074/jbc.M112450200DOI Listing
August 2002

Quercetin glucuronide prevents VSMC hypertrophy by angiotensin II via the inhibition of JNK and AP-1 signaling pathway.

Biochem Biophys Res Commun 2002 May;293(5):1458-65

Department of Pharmacology, The University of Tokushima School of Medicine, 3-18-15 Kuramoto, Tokushima 770-8503, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0200407
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http://dx.doi.org/10.1016/S0006-291X(02)00407-2DOI Listing
May 2002

Hydrogen peroxide stimulates c-Src-mediated big mitogen-activated protein kinase 1 (BMK1) and the MEF2C signaling pathway in PC12 cells: potential role in cell survival following oxidative insults.

J Biol Chem 2002 Mar 8;277(11):9614-21. Epub 2002 Jan 8.

Department of Pharmacology, Pediatrics, Virology, and Clinical Nutrition, the University of Tokushima School of Medicine, Tokushima 770-8503, Japan.

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http://dx.doi.org/10.1074/jbc.M111790200DOI Listing
March 2002