Masahiro Hiraoka

Quality assurance of geometric accuracy based on an electronic portal imaging device and log data analysis for Dynamic WaveArc irradiation.

• Authors:
• Hideaki Hirashima,
• Yuki Miyabe,
• Mitsuhiro Nakamura,
• Nobutaka Mukumoto,
• Takashi Mizowaki,
• Masahiro Hiraoka

• April 2018

Effect of long fasting on myocardial accumulation in 18F-fluorodeoxyglucose positron emission tomography after chemoradiotherapy for esophageal carcinoma.

• Authors:
• Yuichi Ishida,
• Katsuyuki Sakanaka,
• Satoshi Itasaka,
• Yuji Nakamoto,
• Kaori Togashi,
• Takashi Mizowaki,
• Masahiro Hiraoka

• March 2018

Regulatory mechanisms of hypoxia-inducible factor 1 activity: Two decades of knowledge.

• Authors:
• Sho Koyasu,
• Minoru Kobayashi,
• Yoko Goto,
• Masahiro Hiraoka,
• Hiroshi Harada

• March 2018

Five-year outcomes following hypofractionated stereotactic radiotherapy delivered in five fractions for acoustic neuromas: the mean cochlear dose may impact hearing preservation.

• Authors:
• Zhiping Chen,
• Keiichi Takehana,
• Takashi Mizowaki,
• Megumi Uto,
• Kengo Ogura,
• Katsuyuki Sakanaka,
• Yoshiki Arakawa,
• Yohei Mineharu,
• Yuki Miyabe,
• Nobutaka Mukumoto,
• Susumu Miyamoto,
• Masahiro Hiraoka

• March 2018

Decreased acute toxicities of intensity-modulated radiation therapy for localized prostate cancer with prostate-based versus bone-based image guidance.

• Authors:
• Kiyonao Nakamura,
• Takashi Mizowaki,
• Haruo Inokuchi,
• Itaru Ikeda,
• Takahiro Inoue,
• Tomomi Kamba,
• Osamu Ogawa,
• Masahiro Hiraoka

• February 2018

HIF-1 maintains a functional relationship between pancreatic cancer cells and stromal fibroblasts by upregulating expression and secretion of Sonic hedgehog.

• Authors:
• Tomohiro Katagiri,
• Minoru Kobayashi,
• Michio Yoshimura,
• Akiyo Morinibu,
• Satoshi Itasaka,
• Masahiro Hiraoka,
• Hiroshi Harada

• February 2018

Use of a second-dose calculation algorithm to check dosimetric parameters for the dose distribution of a first-dose calculation algorithm for lung SBRT plans.

• Authors:
• Yusuke Tsuruta,
• Mitsuhiro Nakamura,
• Yuki Miyabe,
• Manabu Nakata,
• Yoshitomo Ishihara,
• Nobutaka Mukumoto,
• Mami Akimoto,
• Tomohiro Ono,
• Shinsuke Yano,
• Kyoji Higashimura,
• Yukinori Matsuo,
• Takashi Mizowaki,
• Masahiro Hiraoka

• December 2017

Dosimetric advantages and clinical outcomes of simultaneous integrated boost intensity-modulated radiotherapy for anal squamous cell carcinoma.

• Authors:
• Katsuyuki Sakanaka,
• Satoshi Itasaka,
• Yuichi Ishida,
• Kota Fujii,
• Takahiro Horimatsu,
• Takashi Mizowaki,
• Yoshiharu Sakai,
• Masahiro Hiraoka

• December 2017

Dosimetric impact of translational and rotational setup errors for spine stereotactic body radiotherapy: A phantom study.

• Authors:
• Makoto Sasaki,
• Mitsuhiro Nakamura,
• Nobutaka Mukumoto,
• Manabu Nakata,
• Masahiro Hiraoka

• December 2017

Geometric and dosimetric accuracy of dynamic tumor tracking during volumetric-modulated arc therapy using a gimbal mounted linac.

• Authors:
• Tomohiro Ono,
• Yuki Miyabe,
• Kunio Takahashi,
• Mami Akimoto,
• Nobutaka Mukumoto,
• Yoshitomo Ishihara,
• Mitsuhiro Nakamura,
• Takashi Mizowaki,
• Masahiro Hiraoka

• November 2017

Geometric and dosimetric quality assurance using logfiles and a 3D helical diode detector for Dynamic WaveArc.

• Authors:
• Hideaki Hirashima,
• Mitsuhiro Nakamura,
• Yuki Miyabe,
• Nobutaka Mukumoto,
• Megumi Uto,
• Kiyonao Nakamura,
• Takashi Mizowaki,
• Masahiro Hiraoka

• November 2017

Correlation between urinary dose and delayed radiation cystitis after 78 Gy intensity-modulated radiotherapy for high-risk prostate cancer: A 10-year follow-up study of genitourinary toxicity in clinical practice.

• Authors:
• Haruo Inokuchi,
• Takashi Mizowaki,
• Yoshiki Norihisa,
• Kenji Takayama,
• Itaru Ikeda,
• Kiyonao Nakamura,
• Masahiro Hiraoka

• October 2017

Severe esophagitis associated with cytomegalovirus during concurrent chemoradiotherapy for esophageal cancer.

• Authors:
• Rihito Aizawa,
• Shigemi Matsumoto,
• Yu Uneno,
• Yoshitaka Nishikawa,
• Yoshinao Ozaki,
• Yukiko Mori,
• Masashi Kanai,
• Yuichi Ishida,
• Katsuyuki Sakanaka,
• Masahiro Hiraoka,
• Manabu Muto

• September 2017

Stereotactic body radiotherapy for de novo spinal metastases: systematic review.

• Authors:
• Zain A Husain,
• Arjun Sahgal,
• Antonio De Salles,
• Melissa Funaro,
• Janis Glover,
• Motohiro Hayashi,
• Masahiro Hiraoka,
• Marc Levivier,
• Lijun Ma,
• Roberto Martínez-Alvarez,
• J Ian Paddick,
• Jean Régis,
• Ben J Slotman,
• Samuel Ryu

• September 2017

Estimation of the shielding ability of a tungsten functional paper for diagnostic x-rays and gamma rays.

• Authors:
• Hajime Monzen,
• Ikuo Kanno,
• Takahiro Fujimoto,
• Masahiro Hiraoka

• September 2017

Estimation of lung tumor position from multiple anatomical features on 4D-CT using multiple regression analysis.

• Authors:
• Tomohiro Ono,
• Mitsuhiro Nakamura,
• Yoshinori Hirose,
• Kenji Kitsuda,
• Yuka Ono,
• Takashi Ishigaki,
• Masahiro Hiraoka

• September 2017

Impact of sampling interval in training data acquisition on intrafractional predictive accuracy of indirect dynamic tumor-tracking radiotherapy.

• Authors:
• Nobutaka Mukumoto,
• Mitsuhiro Nakamura,
• Mami Akimoto,
• Yuki Miyabe,
• Kenji Yokota,
• Yukinori Matsuo,
• Takashi Mizowaki,
• Masahiro Hiraoka

• August 2017

Long-term outcomes of intensity-modulated radiotherapy following extra-pleural pneumonectomy for malignant pleural mesothelioma.

• Authors:
• Yukinori Matsuo,
• Keiko Shibuya,
• Kenichi Okubo,
• Nami Ueki,
• Akihiro Aoyama,
• Makoto Sonobe,
• Mitsuhiro Nakamura,
• Takashi Mizowaki,
• Hiroshi Date,
• Masahiro Hiraoka

• July 2017

Assessment of treatment response after lung stereotactic body radiotherapy using diffusion weighted magnetic resonance imaging and positron emission tomography: A pilot study.

• Authors:
• Takashi Shintani,
• Yukinori Matsuo,
• Yusuke Iizuka,
• Takamasa Mitsuyoshi,
• Shigeaki Umeoka,
• Yuji Nakamoto,
• Takashi Mizowaki,
• Kaori Togashi,
• Masahiro Hiraoka

• July 2017

UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization.

• Authors:
• Ryota Nakashima,
• Yoko Goto,
• Sho Koyasu,
• Minoru Kobayashi,
• Akiyo Morinibu,
• Michio Yoshimura,
• Masahiro Hiraoka,
• Ester M Hammond,
• Hiroshi Harada

• July 2017

Development of a four-dimensional Monte Carlo dose calculation system for real-time tumor-tracking irradiation with a gimbaled X-ray head.

• Authors:
• Yoshitomo Ishihara,
• Mitsuhiro Nakamura,
• Yuki Miyabe,
• Nobutaka Mukumoto,
• Yukinori Matsuo,
• Akira Sawada,
• Masaki Kokubo,
• Takashi Mizowaki,
• Masahiro Hiraoka

• March 2017

Evaluation of the prevalence of burnout and psychological morbidity among radiation oncologist members of the Kyoto Radiation Oncology Study Group (KROSG).

• Authors:
• Wambaka Ange Mampuya,
• Yukinori Matsuo,
• Akira Nakamura,
• Masahiro Hiraoka

• March 2017

Regional recurrence in breast cancer patients with one to three positive axillary lymph nodes treated with breast-conserving surgery and whole breast irradiation.

• Authors:
• Kimiko Hirata,
• Michio Yoshimura,
• Minoru Inoue,
• Chikako Yamauchi,
• Masakazu Ogura,
• Masakazu Toi,
• Eiji Suzuki,
• Megumi Takeuchi,
• Masahiro Takada,
• Masahiro Hiraoka

• January 2017

Long-term complications of definitive chemoradiotherapy for esophageal cancer using the classical method.

• Authors:
• Hitoshi Ito,
• Satoshi Itasaka,
• Katsuyuki Sakanaka,
• Norio Araki,
• Takashi Mizowaki,
• Masahiro Hiraoka

• January 2017

A randomized Phase III trial of comparing two dose-fractionations stereotactic body radiotherapy (SBRT) for medically inoperable Stage IA non-small cell lung cancer or small lung lesions clinically diagnosed as primary lung cancer: Japan Clinical Oncology Group Study JCOG1408 (J-SBRT trial).

• Authors:
• Tomoki Kimura,
• Yasushi Nagata,
• Junko Eba,
• Shuichi Ozawa,
• Satoshi Ishikura,
• Taro Shibata,
• Yoshinori Ito,
• Masahiro Hiraoka,
• Yasumasa Nishimura,

• January 2017

Feasibility evaluation of hypofractionated radiotherapy with concurrent temozolomide in elderly patients with glioblastoma.

• Authors:
• Megumi Uto,
• Takashi Mizowaki,
• Kengo Ogura,
• Yoshiki Arakawa,
• Yohei Mineharu,
• Susumu Miyamoto,
• Masahiro Hiraoka

• December 2016

Development of a four-axis moving phantom for patient-specific QA of surrogate signal-based tracking IMRT.

• Authors:
• Nobutaka Mukumoto,
• Mitsuhiro Nakamura,
• Masahiro Yamada,
• Kunio Takahashi,
• Mami Akimoto,
• Yuki Miyabe,
• Kenji Yokota,
• Shuji Kaneko,
• Akira Nakamura,
• Satoshi Itasaka,
• Yukinori Matsuo,
• Takashi Mizowaki,
• Masaki Kokubo,
• Masahiro Hiraoka

• December 2016

Identification of a predictive factor for distant metastasis in esophageal squamous cell carcinoma after definitive chemoradiotherapy.

• Authors:
• Katsuyuki Sakanaka,
• Yuichi Ishida,
• Satoshi Itasaka,
• Yasumasa Ezoe,
• Ikuo Aoyama,
• Shinichi Miyamoto,
• Takahiro Horimatsu,
• Manabu Muto,
• Masahiro Hiraoka

• October 2016

Technical Note: Introduction of variance component analysis to setup error analysis in radiotherapy.

• Authors:
• Yukinori Matsuo,
• Mitsuhiro Nakamura,
• Takashi Mizowaki,
• Masahiro Hiraoka

• September 2016

Dosimetric comparison of lung stereotactic body radiotherapy treatment plans using averaged computed tomography and end-exhalation computed tomography images: Evaluation of the effect of different dose-calculation algorithms and prescription methods.

• Authors:
• Takamasa Mitsuyoshi,
• Mitsuhiro Nakamura,
• Yukinori Matsuo,
• Nami Ueki,
• Akira Nakamura,
• Yusuke Iizuka,
• Wambaka Ange Mampuya,
• Takashi Mizowaki,
• Masahiro Hiraoka

• September 2016

[Clinical Efficacy of Cepharanthin(R)for Radiotherapy-Induced Leukopenia - A Nationwide, Multicenter, and Observational Study].

• Authors:
• Shuichi Kanamori,
• Masahiro Hiraoka,
• Noboru Fukuhara,
• Yukio Oizumi,
• Atsushi Danjo,
• Kensei Nakata,
• Kazuhiko Owaki,
• Yasumasa Nishimura

• September 2016

Ten-year outcomes of intensity-modulated radiation therapy combined with neoadjuvant hormonal therapy for intermediate- and high-risk patients with T1c-T2N0M0 prostate cancer.

• Authors:
• Takashi Mizowaki,
• Yoshiki Norihisa,
• Kenji Takayama,
• Itaru Ikeda,
• Haruo Inokuchi,
• Kiyonao Nakamura,
• Tomomi Kamba,
• Takahiro Inoue,
• Toshiyuki Kamoto,
• Osamu Ogawa,
• Masahiro Hiraoka

• August 2016

Stereotactic body radiotherapy versus lobectomy for operable clinical stage IA lung adenocarcinoma: comparison of survival outcomes in two clinical trials with propensity score analysis (JCOG1313-A).

• Authors:
• Junko Eba,
• Kenichi Nakamura,
• Junki Mizusawa,
• Kenji Suzuki,
• Yasushi Nagata,
• Teruaki Koike,
• Masahiro Hiraoka,
• Shun-Ichi Watanabe,
• Satoshi Ishikura,
• Hisao Asamura,
• Haruhiko Fukuda,

• August 2016

Non-coplanar volumetric-modulated arc therapy (VMAT) for craniopharyngiomas reduces radiation doses to the bilateral hippocampus: a planning study comparing dynamic conformal arc therapy, coplanar VMAT, and non-coplanar VMAT.

• Authors:
• Megumi Uto,
• Takashi Mizowaki,
• Kengo Ogura,
• Masahiro Hiraoka

• June 2016

[History of radiation oncology and present state].

• Authors:
• Haruo Inokuchi,
• Masahiro Hiraoka

• May 2016

Multivariate analysis for the estimation of target localization errors in fiducial marker-based radiotherapy.

• Authors:
• Masanori Takamiya,
• Mitsuhiro Nakamura,
• Mami Akimoto,
• Nami Ueki,
• Masahiro Yamada,
• Hiroaki Tanabe,
• Yukinori Matsuo,
• Takashi Mizowaki,
• Masaki Kokubo,
• Masahiro Hiraoka,
• Akio Itoh

• April 2016

Initial characterization, dosimetric benchmark and performance validation of Dynamic Wave Arc.

• Authors:
• Manuela Burghelea,
• Dirk Verellen,
• Kenneth Poels,
• Cecilia Hung,
• Mitsuhiro Nakamura,
• Jennifer Dhont,
• Thierry Gevaert,
• Robbe Van den Begin,
• Christine Collen,
• Yukinori Matsuo,
• Takahiro Kishi,
• Viorica Simon,
• Masahiro Hiraoka,
• Mark de Ridder

• April 2016

Long-term outcomes of intensity-modulated radiation therapy combined with neoadjuvant androgen deprivation therapy under an early salvage policy for patients with T3-T4N0M0 prostate cancer.

• Authors:
• Takashi Mizowaki,
• Yoshiki Norihisa,
• Kenji Takayama,
• Itaru Ikeda,
• Haruo Inokuchi,
• Kiyonao Nakamura,
• Tomomi Kamba,
• Takahiro Inoue,
• Toshiyuki Kamoto,
• Osamu Ogawa,
• Masahiro Hiraoka

• February 2016

Clinical effect of multileaf collimator width on the incidence of late rectal bleeding after high-dose intensity-modulated radiotherapy for localized prostate carcinoma.

• Authors:
• Haruo Inokuchi,
• Takashi Mizowaki,
• Yoshiki Norihisa,
• Kenji Takayama,
• Itaru Ikeda,
• Kiyonao Nakamura,
• Mitsuhiro Nakamura,
• Masahiro Hiraoka

• February 2016

L-Phenylalanine preloading reduces the (10)B(n, α)(7)Li dose to the normal brain by inhibiting the uptake of boronophenylalanine in boron neutron capture therapy for brain tumours.

• Authors:
• Tsubasa Watanabe,
• Hiroki Tanaka,
• Satoshi Fukutani,
• Minoru Suzuki,
• Masahiro Hiraoka,
• Koji Ono

• January 2016

Potent anti-tumor effects of EGFR-targeted hybrid peptide on mice bearing liver metastases.

• Authors:
• Arong Gaowa,
• Tomohisa Horibe,
• Masayuki Kohno,
• Hiroshi Harada,
• Masahiro Hiraoka,
• Koji Kawakami

• January 2016

Target localization errors from fiducial markers implanted around a lung tumor for dynamic tumor tracking.

• Authors:
• Mitsuhiro Nakamura,
• Masanori Takamiya,
• Mami Akimoto,
• Nami Ueki,
• Masahiro Yamada,
• Hiroaki Tanabe,
• Nobutaka Mukumoto,
• Kenji Yokota,
• Yukinori Matsuo,
• Takashi Mizowaki,
• Masaki Kokubo,
• Masahiro Hiraoka

• December 2015

Dynamic tumor-tracking radiotherapy with real-time monitoring for liver tumors using a gimbal mounted linac.

• Authors:
• Yusuke Iizuka,
• Yukinori Matsuo,
• Yoshitomo Ishihara,
• Mami Akimoto,
• Hiroaki Tanabe,
• Kenji Takayama,
• Nami Ueki,
• Kenji Yokota,
• Takashi Mizowaki,
• Masaki Kokubo,
• Masahiro Hiraoka

• December 2015

Prospective Trial of Stereotactic Body Radiation Therapy for Both Operable and Inoperable T1N0M0 Non-Small Cell Lung Cancer: Japan Clinical Oncology Group Study JCOG0403.

• Authors:
• Yasushi Nagata,
• Masahiro Hiraoka,
• Taro Shibata,
• Hiroshi Onishi,
• Masaki Kokubo,
• Katsuyuki Karasawa,
• Yoshiyuki Shioyama,
• Rikiya Onimaru,
• Takuyo Kozuka,
• Etsuo Kunieda,
• Tsutomu Saito,
• Keiichi Nakagawa,
• Masato Hareyama,
• Yoshihiro Takai,
• Kazushige Hayakawa,
• Norio Mitsuhashi,
• Satoshi Ishikura

• December 2015

Treatment and Prognosis of Isolated Local Relapse after Stereotactic Body Radiotherapy for Clinical Stage I Non-Small-Cell Lung Cancer: Importance of Salvage Surgery.

• Authors:
• Masatsugu Hamaji,
• Fengshi Chen,
• Yukinori Matsuo,
• Nami Ueki,
• Masahiro Hiraoka,
• Hiroshi Date

• November 2015

PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase.

• Authors:
• Minoru Inoue,
• Michio Yoshimura,
• Minoru Kobayashi,
• Akiyo Morinibu,
• Satoshi Itasaka,
• Masahiro Hiraoka,
• Hiroshi Harada

• October 2015

A novel method to visually determine the intracellular pH of xenografted tumor in vivo by utilizing fluorescent protein as an indicator.

• Authors:
• Shotaro Tanaka,
• Hiroshi Harada,
• Masahiro Hiraoka

• September 2015

Phase I study of stereotactic body radiation therapy for peripheral T2N0M0 non-small cell lung cancer with PTV<100 cc using a continual reassessment method (JCOG0702).

• Authors:
• Rikiya Onimaru,
• Hiroki Shirato,
• Taro Shibata,
• Masahiro Hiraoka,
• Satoshi Ishikura,
• Katsuyuki Karasawa,
• Yukinori Matsuo,
• Masaki Kokubo,
• Yoshiyuki Shioyama,
• Haruo Matsushita,
• Yoshinori Ito,
• Hiroshi Onishi

• August 2015

Dose calculation accuracies in whole breast radiotherapy treatment planning: a multi-institutional study.

• Authors:
• Shogo Hatanaka,
• Yuki Miyabe,
• Naoki Tohyama,
• Yu Kumazaki,
• Masahiko Kurooka,
• Hiroyuki Okamoto,
• Hidenobu Tachibana,
• Satoshi Kito,
• Akihisa Wakita,
• Yuko Ohotomo,
• Hiroyuki Ikagawa,
• Satoshi Ishikura,
• Miwako Nozaki,
• Yoshikazu Kagami,
• Masahiro Hiraoka,
• Teiji Nishio

• July 2015

Combination of BMP-2-releasing gelatin/β-TCP sponges with autologous bone marrow for bone regeneration of X-ray-irradiated rabbit ulnar defects.

• Authors:
• Masaya Yamamoto,
• Akishige Hokugo,
• Yoshitake Takahashi,
• Takayoshi Nakano,
• Masahiro Hiraoka,
• Yasuhiko Tabata

• July 2015

Geometric Verification of Dynamic Wave Arc Delivery With the Vero System Using Orthogonal X-ray Fluoroscopic Imaging.

• Authors:
• Manuela Burghelea,
• Dirk Verellen,
• Kenneth Poels,
• Thierry Gevaert,
• Tom Depuydt,
• Koen Tournel,
• Cecilia Hung,
• Viorica Simon,
• Masahiro Hiraoka,
• Mark de Ridder

• July 2015

Pretreatment Modified Glasgow Prognostic Score Predicts Clinical Outcomes After Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer.

• Authors:
• Takahiro Kishi,
• Yukinori Matsuo,
• Nami Ueki,
• Yusuke Iizuka,
• Akira Nakamura,
• Katsuyuki Sakanaka,
• Takashi Mizowaki,
• Masahiro Hiraoka

• July 2015

Radiation sensitivity assay with a panel of patient-derived spheroids of small cell carcinoma of the cervix.

• Authors:
• Aya Nakajima,
• Hiroko Endo,
• Hiroaki Okuyama,
• Yumiko Kiyohara,
• Tadashi Kimura,
• Shoji Kamiura,
• Masahiro Hiraoka,
• Masahiro Inoue

• June 2015

A multi-centre analysis of treatment procedures and error components in dynamic tumour tracking radiotherapy.

• Authors:
• Yukinori Matsuo,
• Dirk Verellen,
• Kenneth Poels,
• Nobutaka Mukumoto,
• Tom Depuydt,
• Mami Akimoto,
• Mitsuhiro Nakamura,
• Nami Ueki,
• Benedikt Engels,
• Christine Collen,
• Masaki Kokubo,
• Masahiro Hiraoka,
• Mark de Ridder

• June 2015

Influence of the correlation modeling period on the prediction accuracy of infrared marker-based dynamic tumor tracking using a gimbaled X-ray head.

• Authors:
• Mitsuhiro Nakamura,
• Mami Akimoto,
• Nobutaka Mukumoto,
• Masahiro Yamada,
• Hiroaki Tanabe,
• Nami Ueki,
• Yukinori Matsuo,
• Takashi Mizowaki,
• Masaki Kokubo,
• Masahiro Hiraoka

• May 2015

Enhancement of anti-tumor activity of hybrid peptide in conjugation with carboxymethyl dextran via disulfide linkers.

• Authors:
• Arong Gaowa,
• Tomohisa Horibe,
• Masayuki Kohno,
• Yasuhiko Tabata,
• Hiroshi Harada,
• Masahiro Hiraoka,
• Koji Kawakami

• May 2015

Video-assisted thoracoscopic lobectomy versus stereotactic radiotherapy for stage I lung cancer.

• Authors:
• Masatsugu Hamaji,
• Fengshi Chen,
• Yukinori Matsuo,
• Atsushi Kawaguchi,
• Satoshi Morita,
• Nami Ueki,
• Makoto Sonobe,
• Yasushi Nagata,
• Masahiro Hiraoka,
• Hiroshi Date

• April 2015

Improvement of registration accuracy in accelerated partial breast irradiation using the point-based rigid-body registration algorithm for patients with implanted fiducial markers.

• Authors:
• Minoru Inoue,
• Michio Yoshimura,
• Sayaka Sato,
• Mitsuhiro Nakamura,
• Masahiro Yamada,
• Kimiko Hirata,
• Makoto Sasaki,
• Takahiro Fujimoto,
• Masakazu Ogura,
• Masahiro Hiraoka

• April 2015

Definitive radiotherapy for head and neck squamous cell carcinoma: update and perspectives on the basis of EBM.

• Authors:
• Takeshi Kodaira,
• Yasumasa Nishimura,
• Yoshikazu Kagami,
• Yoshinori Ito,
• Naoto Shikama,
• Satoshi Ishikura,
• Masahiro Hiraoka

• March 2015

Baseline correction of a correlation model for improving the prediction accuracy of infrared marker-based dynamic tumor tracking.

• Authors:
• Mami Akimoto,
• Mitsuhiro Nakamura,
• Nobutaka Mukumoto,
• Masahiro Yamada,
• Hiroaki Tanabe,
• Nami Ueki,
• Shuji Kaneko,
• Yukinori Matsuo,
• Takashi Mizowaki,
• Masaki Kokubo,
• Masahiro Hiraoka

• March 2015

Commissioning and quality assurance of Dynamic WaveArc irradiation.

• Authors:
• Sayaka Sato,
• Yuki Miyabe,
• Kunio Takahashi,
• Masahiro Yamada,
• Mitsuhiro Nakamura,
• Yoshitomo Ishihara,
• Kenji Yokota,
• Shuji Kaneko,
• Takashi Mizowaki,
• Hajime Monzen,
• Masahiro Hiraoka

• March 2015

Interfraction positional variation in pancreatic tumors using daily breath-hold cone-beam computed tomography with visual feedback.

• Authors:
• Mitsuhiro Nakamura,
• Mami Akimoto,
• Tomohiro Ono,
• Akira Nakamura,
• Shinsuke Yano,
• Manabu Nakata,
• Satoshi Itasaka,
• Takashi Mizowaki,
• Keiko Shibuya,
• Masahiro Hiraoka

• March 2015

Recurrence patterns after postoperative radiotherapy for squamous cell carcinoma of the pharynx and larynx.

• Authors:
• Yusuke Iizuka,
• Michio Yoshimura,
• Haruo Inokuchi,
• Yukinori Matsuo,
• Akira Nakamura,
• Takashi Mizowaki,
• Shigeru Hirano,
• Morimasa Kitamura,
• Ichiro Tateya,
• Masahiro Hiraoka

• January 2015

Impact of pretreatment interstitial lung disease on radiation pneumonitis and survival after stereotactic body radiation therapy for lung cancer.

• Authors:
• Nami Ueki,
• Yukinori Matsuo,
• Yosuke Togashi,
• Takeshi Kubo,
• Keiko Shibuya,
• Yusuke Iizuka,
• Takashi Mizowaki,
• Kaori Togashi,
• Michiaki Mishima,
• Masahiro Hiraoka

• January 2015

UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α.

• Authors:
• Yoko Goto,
• Lihua Zeng,
• Chan Joo Yeom,
• Yuxi Zhu,
• Akiyo Morinibu,
• Kazumi Shinomiya,
• Minoru Kobayashi,
• Kiichi Hirota,
• Satoshi Itasaka,
• Michio Yoshimura,
• Keiji Tanimoto,
• Masae Torii,
• Terumasa Sowa,
• Toshi Menju,
• Makoto Sonobe,
• Hideaki Kakeya,
• Masakazu Toi,
• Hiroshi Date,
• Ester M Hammond,
• Masahiro Hiraoka,
• Hiroshi Harada

• January 2015

[Recent progress in radiation therapy].

• Authors:
• Masahiro Hiraoka,
• Haruo Inokuchi

• December 2014

Dosimetric shield evaluation with tungsten sheet in 4, 6, and 9MeV electron beams.

• Authors:
• Takahiro Fujimoto,
• Hajime Monzen,
• Manabu Nakata,
• Takashi Okada,
• Shinsuke Yano,
• Toru Takakura,
• Junichi Kuwahara,
• Makoto Sasaki,
• Kyoji Higashimura,
• Masahiro Hiraoka

• November 2014

Prediction of clinical outcome after stereotactic body radiotherapy for non-small cell lung cancer using diffusion-weighted MRI and (18)F-FDG PET.

• Authors:
• Yusuke Iizuka,
• Yukinori Matsuo,
• Shigeaki Umeoka,
• Yuji Nakamoto,
• Nami Ueki,
• Takashi Mizowaki,
• Kaori Togashi,
• Masahiro Hiraoka

• November 2014

Comparison of long-term survival outcomes between stereotactic body radiotherapy and sublobar resection for stage I non-small-cell lung cancer in patients at high risk for lobectomy: A propensity score matching analysis.

• Authors:
• Yukinori Matsuo,
• Fengshi Chen,
• Masatsugu Hamaji,
• Atsushi Kawaguchi,
• Nami Ueki,
• Yasushi Nagata,
• Makoto Sonobe,
• Satoshi Morita,
• Hiroshi Date,
• Masahiro Hiraoka

• November 2014

Development of a dose verification system for Vero4DRT using Monte Carlo method.

• Authors:
• Yoshitomo Ishihara,
• Akira Sawada,
• Mitsuhiro Nakamura,
• Yuki Miyabe,
• Hiroaki Tanabe,
• Shuji Kaneko,
• Kenji Takayama,
• Takashi Mizowaki,
• Masaki Kokubo,
• Masahiro Hiraoka

• November 2014

Development of an expanded-field irradiation technique using a gimbaled x-ray head.

• Authors:
• Tomohiro Ono,
• Yuki Miyabe,
• Masahiro Yamada,
• Kenji Yokota,
• Shuji Kaneko,
• Akira Sawada,
• Hajime Monzen,
• Takashi Mizowaki,
• Masaki Kokubo,
• Masahiro Hiraoka

• October 2014

The impact of abdominal compression on outcome in patients treated with stereotactic body radiotherapy for primary lung cancer.

• Authors:
• Wambaka Ange Mampuya,
• Yukinori Matsuo,
• Nami Ueki,
• Mitsuhiro Nakamura,
• Nobutaka Mukumoto,
• Akira Nakamura,
• Yusuke Iizuka,
• Takahiro Kishi,
• Takashi Mizowaki,
• Masahiro Hiraoka

• September 2014

Evaluation of dynamic tumour tracking radiotherapy with real-time monitoring for lung tumours using a gimbal mounted linac.

• Authors:
• Yukinori Matsuo,
• Nami Ueki,
• Kenji Takayama,
• Mitsuhiro Nakamura,
• Yuki Miyabe,
• Yoshitomo Ishihara,
• Nobutaka Mukumoto,
• Shinsuke Yano,
• Hiroaki Tanabe,
• Shuji Kaneko,
• Takashi Mizowaki,
• Hajime Monzen,
• Akira Sawada,
• Masaki Kokubo,
• Masahiro Hiraoka

• September 2014

Sonication-induced formation of size-controlled self-assemblies of amphiphilic Janus-type polymers as optical tumor-imaging agents.

• Authors:
• Koji Miki,
• Hiroki Hashimoto,
• Tatsuhiro Inoue,
• Hideki Matsuoka,
• Hiroshi Harada,
• Masahiro Hiraoka,
• Kouichi Ohe

• August 2014

Dosimetric comparison of Acuros XB, AAA, and XVMC in stereotactic body radiotherapy for lung cancer.

• Authors:
• Yusuke Tsuruta,
• Manabu Nakata,
• Mitsuhiro Nakamura,
• Yukinori Matsuo,
• Kyoji Higashimura,
• Hajime Monzen,
• Takashi Mizowaki,
• Masahiro Hiraoka

• August 2014

Accuracy of positional correction for the floor-mounted kV X-ray IGRT system in angled couch positions.

• Authors:
• Satoshi Koubuchi,
• Toru Takakura,
• Mitsuhiro Nakamura,
• Takashi Mizowaki,
• Manabu Nakata,
• Masahiro Hiraoka

• July 2014

Intrafractional tracking accuracy in infrared marker-based hybrid dynamic tumour-tracking irradiation with a gimballed linac.

• Authors:
• Nobutaka Mukumoto,
• Mitsuhiro Nakamura,
• Masahiro Yamada,
• Kunio Takahashi,
• Hiroaki Tanabe,
• Shinsuke Yano,
• Yuki Miyabe,
• Nami Ueki,
• Shuji Kaneko,
• Yukinori Matsuo,
• Takashi Mizowaki,
• Akira Sawada,
• Masaki Kokubo,
• Masahiro Hiraoka

• May 2014

[Use of surgical clips to verify positional accuracy in image-guided accelerated partial breast irradiation].

• Authors:
• Makoto Sasaki,
• Manabu Nakata,
• Minoru Inoue,
• Sayaka Sato,
• Mitsuhiro Nakamura,
• Takahiro Fujimoto,
• Yusuke Tsuruta,
• Shinsuke Yano,
• Kyouji Higashimura,
• Michio Yoshimura,
• Masahiro Hiraoka

• May 2014

Dosimetric impact of gold markers implanted closely to lung tumors: a Monte Carlo simulation.

• Authors:
• Takehiro Shiinoki,
• Akira Sawada,
• Yoshitomo Ishihara,
• Yuki Miyabe,
• Yukinori Matsuo,
• Takashi Mizowaki,
• Masaki Kokubo,
• Masahiro Hiraoka

• May 2014

Pineal parenchymal tumor of intermediate differentiation: Treatment outcomes of five cases.

• Authors:
• Tsubasa Watanabe,
• Takashi Mizowaki,
• Yoshiki Arakawa,
• Yusuke Iizuka,
• Kengo Ogura,
• Katsuyuki Sakanaka,
• Susumu Miyamoto,
• Masahiro Hiraoka

• March 2014

Dosimetric advantages of O-ring design radiotherapy system for skull-base tumors.

• Authors:
• Kengo Ogura,
• Takashi Mizowaki,
• Yuichi Ishida,
• Masahiro Hiraoka

• March 2014

Protection of cardiomyocytes from the hypoxia-mediated injury by a peptide targeting the activator of G-protein signaling 8.

• Authors:
• Motohiko Sato,
• Masahiro Hiraoka,
• Hiroko Suzuki,
• Miho Sakima,
• Abdullah Al Mamun,
• Yukiko Yamane,
• Takayuki Fujita,
• Utako Yokoyama,
• Satoshi Okumura,
• Yoshihiro Ishikawa

Effect of intrafractional prostate motion on simultaneous boost intensity-modulated radiotherapy to the prostate: a simulation study based on intrafractional motion in the prone position.

• Authors:
• Itaru Ikeda,
• Takashi Mizowaki,
• Tomohiro Ono,
• Masahiro Yamada,
• Mitsuhiro Nakamura,
• Hajime Monzen,
• Shinsuke Yano,
• Masahiro Hiraoka

Dosimetric evaluation of the Acuros XB algorithm for a 4 MV photon beam in head and neck intensity-modulated radiation therapy.

• Authors:
• Kimiko Hirata,
• Mitsuhiro Nakamura,
• Michio Yoshimura,
• Nobutaka Mukumoto,
• Manabu Nakata,
• Hitoshi Ito,
• Haruo Inokuchi,
• Yukinori Matsuo,
• Takashi Mizowaki,
• Masahiro Hiraoka

Pretreatment C-reactive protein level predicts outcome and patterns of failure after chemoradiotherapy for locally advanced pancreatic cancer.

• Authors:
• Takahiro Kishi,
• Akira Nakamura,
• Satoshi Itasaka,
• Keiko Shibuya,
• Shigemi Matsumoto,
• Masashi Kanai,
• Yuzo Kodama,
• Kyoichi Takaori,
• Takashi Mizowaki,
• Masahiro Hiraoka

Long-term stability assessment of a 4D tumor tracking system integrated into a gimbaled linear accelerator.

• Authors:
• Mami Akimoto,
• Mitsuhiro Nakamura,
• Yuki Miyabe,
• Nobutaka Mukumoto,
• Kenji Yokota,
• Takashi Mizowaki,
• Masahiro Hiraoka

A multicenter phase I study of preoperative chemoradiotherapy with S-1 and irinotecan for locally advanced lower rectal cancer (SAMRAI-1).

• Authors:
• Takeo Sato,
• Kazushige Hayakawa,
• Naohiro Tomita,
• Masafumi Noda,
• Norihiko Kamikonya,
• Toshiaki Watanabe,
• Daiki Kato,
• Yoshiharu Sakai,
• Masahiro Hiraoka,
• Mitsuo Shimada,
• Hitoshi Ikushima,
• Hideo Baba,
• Natsuo Oya,
• Masatoshi Oya,
• Keiko Nemoto-Murofushi,
• Masahiro Takeuchi,
• Masahiko Watanabe

Comparative evaluation of respiratory-gated and ungated FDG-PET for target volume definition in radiotherapy treatment planning for pancreatic cancer.

• Authors:
• Takahiro Kishi,
• Yukinori Matsuo,
• Akira Nakamura,
• Yuji Nakamoto,
• Satoshi Itasaka,
• Takashi Mizowaki,
• Kaori Togashi,
• Masahiro Hiraoka

LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis.

• Authors:
• Chan Joo Yeom,
• Lihua Zeng,
• Yoko Goto,
• Akiyo Morinibu,
• Yuxi Zhu,
• Kazumi Shinomiya,
• Minoru Kobayashi,
• Satoshi Itasaka,
• Michio Yoshimura,
• Cheol-Goo Hur,
• Hideaki Kakeya,
• Ester M Hammond,
• Masahiro Hiraoka,
• Hiroshi Harada

Difference in dose-volumetric data between the analytical anisotropic algorithm, the dose-to-medium, and the dose-to-water reporting modes of the Acuros XB for lung stereotactic body radiation therapy.

• Authors:
• Wambaka A Mampuya,
• Mitsuhiro Nakamura,
• Yoshinori Hirose,
• Kenji Kitsuda,
• Takashi Ishigaki,
• Takashi Mizowaki,
• Masahiro Hiraoka

The accuracy of extracted target motion trajectories in four-dimensional cone-beam computed tomography for lung cancer patients.

• Authors:
• Hiraku Iramina,
• Mitsuhiro Nakamura,
• Yusuke Iizuka,
• Takamasa Mitsuyoshi,
• Yukinori Matsuo,
• Takashi Mizowaki,
• Masahiro Hiraoka,
• Ikuo Kanno

Comparison of the pharmacokinetics between L-BPA and L-FBPA using the same administration dose and protocol: a validation study for the theranostic approach using [F]-L-FBPA positron emission tomography in boron neutron capture therapy.

• Authors:
• Tsubasa Watanabe,
• Yoshihide Hattori,
• Youichiro Ohta,
• Miki Ishimura,
• Yosuke Nakagawa,
• Yu Sanada,
• Hiroki Tanaka,
• Satoshi Fukutani,
• Shin-Ichiro Masunaga,
• Masahiro Hiraoka,
• Koji Ono,
• Minoru Suzuki,
• Mitsunori Kirihata

Phase I study of stereotactic body radiation therapy for peripheral T2N0M0 non-small cell lung cancer (JCOG0702): Results for the group with PTV⩾100cc.

• Authors:
• Rikiya Onimaru,
• Hiroshi Onishi,
• Taro Shibata,
• Masahiro Hiraoka,
• Satoshi Ishikura,
• Katsuyuki Karasawa,
• Yukinori Matsuo,
• Masaki Kokubo,
• Yoshiyuki Shioyama,
• Haruo Matsushita,
• Yoshinori Ito,
• Hiroki Shirato

Optimization of Couch Modeling in the Change of Dose Calculation Methods and Their Versions.

• Authors:
• Junichi Kuwahara,
• Manabu Nakata,
• Takahiro Fujimoto,
• Mitsuhiro Nakamura,
• Makoto Sasaki,
• Yusuke Tsuruta,
• Shinsuke Yano,
• Kyoji Higashimura,
• Masahiro Hiraoka

Three-dimensional intrafractional internal target motions in accelerated partial breast irradiation using three-dimensional conformal external beam radiotherapy.

• Authors:
• Kimiko Hirata,
• Michio Yoshimura,
• Nobutaka Mukumoto,
• Mitsuhiro Nakamura,
• Minoru Inoue,
• Makoto Sasaki,
• Takahiro Fujimoto,
• Shinsuke Yano,
• Manabu Nakata,
• Takashi Mizowaki,
• Masahiro Hiraoka

Volumetric modulated Dynamic WaveArc therapy reduces the dose to the hippocampus in patients with pituitary adenomas and craniopharyngiomas.

• Authors:
• Megumi Uto,
• Takashi Mizowaki,
• Kengo Ogura,
• Yuki Miyabe,
• Mitsuhiro Nakamura,
• Nobutaka Mukumoto,
• Hideaki Hirashima,
• Masahiro Hiraoka

Inter- and Intrafractional Variation in the 3-Dimensional Positions of Pancreatic Tumors Due to Respiration Under Real-Time Monitoring.

• Authors:
• Mami Akimoto,
• Mitsuhiro Nakamura,
• Akira Nakamura,
• Nobutaka Mukumoto,
• Takashi Kishi,
• Yoko Goto,
• Takashi Mizowaki,
• Masahiro Hiraoka

Prognostic Significance of Serum CEA for Non-small Cell Lung Cancer Patients Receiving Stereotactic Body Radiotherapy.

• Authors:
• Takashi Shintani,
• Yukinori Matsuo,
• Yusuke Iizuka,
• Takamasa Mitsuyoshi,
• Takashi Mizowaki,
• Masahiro Hiraoka

A circadian clock gene, PER2, activates HIF-1 as an effector molecule for recruitment of HIF-1α to promoter regions of its downstream genes.

• Authors:
• Minoru Kobayashi,
• Akiyo Morinibu,
• Sho Koyasu,
• Yoko Goto,
• Masahiro Hiraoka,
• Hiroshi Harada

ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair.

• Authors:
• Masataka Tsuda,
• Kosai Cho,
• Masato Ooka,
• Naoto Shimizu,
• Reiko Watanabe,
• Akira Yasui,
• Yuka Nakazawa,
• Tomoo Ogi,
• Hiroshi Harada,
• Keli Agama,
• Jun Nakamura,
• Ryuta Asada,
• Haruna Fujiike,
• Tetsushi Sakuma,
• Takashi Yamamoto,
• Junko Murai,
• Masahiro Hiraoka,
• Kaoru Koike,
• Yves Pommier,
• Shunichi Takeda,
• Kouji Hirota