Publications

Geometric and dosimetric accuracy of dynamic tumor tracking during volumetric-modulated arc therapy using a gimbal mounted linac.
Radiother Oncol 2017 Nov 11. Epub 2017 Nov 11.
Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Japan; Department of Radiation Oncology, Wakayama Red Cross Hospital, Japan.

Volumetric modulated Dynamic WaveArc therapy reduces the dose to the hippocampus in patients with pituitary adenomas and craniopharyngiomas.
Pract Radiat Oncol 2017 Nov - Dec;7(6):382-387. Epub 2017 Apr 13.
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, Japan.

Inter- and Intrafractional Variation in the 3-Dimensional Positions of Pancreatic Tumors Due to Respiration Under Real-Time Monitoring.
Int J Radiat Oncol Biol Phys 2017 Aug 31;98(5):1204-1211. Epub 2017 Mar 31.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Long-term outcomes of intensity-modulated radiotherapy following extra-pleural pneumonectomy for malignant pleural mesothelioma.
Acta Oncol 2017 Jul 24;56(7):957-962. Epub 2017 Jan 24.
a Department of Radiation Oncology and Image-applied Therapy , Graduate School of Medicine, Kyoto University , Kyoto , Japan.

Three-dimensional intrafractional internal target motions in accelerated partial breast irradiation using three-dimensional conformal external beam radiotherapy.
Radiother Oncol 2017 Jul 19;124(1):118-123. Epub 2017 May 19.
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto University, Japan.


Decreased acute toxicities of intensity-modulated radiation therapy for localized prostate cancer with prostate-based versus bone-based image guidance.
Int J Clin Oncol 2017 Jul 29. Epub 2017 Jul 29.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.


UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization.
Sci Rep 2017 Jul 31;7(1):6879. Epub 2017 Jul 31.
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Development of a four-dimensional Monte Carlo dose calculation system for real-time tumor-tracking irradiation with a gimbaled X-ray head.
Phys Med 2017 Mar 16;35:59-65. Epub 2017 Feb 16.
Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.


Regional recurrence in breast cancer patients with one to three positive axillary lymph nodes treated with breast-conserving surgery and whole breast irradiation.
J Radiat Res 2017 Jan 15;58(1):79-85. Epub 2016 Jul 15.
Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan.


Feasibility evaluation of hypofractionated radiotherapy with concurrent temozolomide in elderly patients with glioblastoma.
Int J Clin Oncol 2016 Dec 6;21(6):1023-1029. Epub 2016 Jul 6.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.


Identification of a predictive factor for distant metastasis in esophageal squamous cell carcinoma after definitive chemoradiotherapy.
Int J Clin Oncol 2016 Oct 2;21(5):899-908. Epub 2016 Mar 2.
Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, 54 Sho-goin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.


Ten-year outcomes of intensity-modulated radiation therapy combined with neoadjuvant hormonal therapy for intermediate- and high-risk patients with T1c-T2N0M0 prostate cancer.
Int J Clin Oncol 2016 Aug 3;21(4):783-790. Epub 2016 Feb 3.
Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.



Non-coplanar volumetric-modulated arc therapy (VMAT) for craniopharyngiomas reduces radiation doses to the bilateral hippocampus: a planning study comparing dynamic conformal arc therapy, coplanar VMAT, and non-coplanar VMAT.
Radiat Oncol 2016 Jun 23;11:86. Epub 2016 Jun 23.
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Initial characterization, dosimetric benchmark and performance validation of Dynamic Wave Arc.
Radiat Oncol 2016 Apr 29;11:63. Epub 2016 Apr 29.
Department of Radiotherapy, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Laarbeeklaan 101, B-1090, Brussels, Belgium.

Long-term outcomes of intensity-modulated radiation therapy combined with neoadjuvant androgen deprivation therapy under an early salvage policy for patients with T3-T4N0M0 prostate cancer.
Int J Clin Oncol 2016 Feb 4;21(1):148-55. Epub 2015 Jul 4.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Clinical effect of multileaf collimator width on the incidence of late rectal bleeding after high-dose intensity-modulated radiotherapy for localized prostate carcinoma.
Int J Clin Oncol 2016 Feb 12;21(1):156-61. Epub 2015 Jul 12.
Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

L-Phenylalanine preloading reduces the (10)B(n, α)(7)Li dose to the normal brain by inhibiting the uptake of boronophenylalanine in boron neutron capture therapy for brain tumours.
Cancer Lett 2016 Jan 8;370(1):27-32. Epub 2015 Oct 8.
Department of Nuclear Science and Engineering, Kyoto University Research Reactor Institute, Osaka 590-0494, Japan. Electronic address:

Target localization errors from fiducial markers implanted around a lung tumor for dynamic tumor tracking.
Phys Med 2015 Dec 10;31(8):934-941. Epub 2015 Jul 10.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, Japan.



Dose calculation accuracies in whole breast radiotherapy treatment planning: a multi-institutional study.
Radiol Phys Technol 2015 Jul 3;8(2):200-8. Epub 2015 Feb 3.
Department of Radiation Oncology, Saitama Medical University Saitama Medical Center, 1981, Kamoda, Kawagoe City, Saitama, 350-8550, Japan,

Radiation sensitivity assay with a panel of patient-derived spheroids of small cell carcinoma of the cervix.
Int J Cancer 2015 Jun 11;136(12):2949-60. Epub 2014 Dec 11.
Department of Biochemistry, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan; Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan.



Impact of pretreatment interstitial lung disease on radiation pneumonitis and survival after stereotactic body radiation therapy for lung cancer.
J Thorac Oncol 2015 Jan;10(1):116-25
*Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, Japan; †Department of Genome Biology, Kinki University Faculty of Medicine, Osaka-Sayama, Japan; ‡Departments of Respiratory Medicine, and §Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan; and ‖Department of Therapeutic Radiology, Yamaguchi University Graduate School of Medicine, Ube, Japan.

UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α.
Nat Commun 2015 Jan 23;6:6153. Epub 2015 Jan 23.
1] Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Kyoto 606-8507, Japan [2] Group of Radiation and Tumor Biology, Career-Path Promotion Unit for Young Life Scientists, Kyoto University, Yoshida Konoe-cho, Kyoto 606-8501, Japan [3] Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency (JST), 4-1-8 Honcho, Saitama 332-0012, Japan.

Dosimetric shield evaluation with tungsten sheet in 4, 6, and 9MeV electron beams.
Phys Med 2014 Nov 19;30(7):838-42. Epub 2014 Jun 19.
Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, 54 Kawara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.


The impact of abdominal compression on outcome in patients treated with stereotactic body radiotherapy for primary lung cancer.
J Radiat Res 2014 Sep 6;55(5):934-9. Epub 2014 May 6.
Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.


Radiotherapy for patients with isolated local recurrence of primary resected pancreatic cancer. Prolonged disease-free interval associated with favorable prognosis.
Strahlenther Onkol 2014 May 6;190(5):485-90. Epub 2014 Mar 6.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 606-8507, Kyoto, Japan,


HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs.
Sci Rep 2014 Jan 23;4:3793. Epub 2014 Jan 23.
1] Group of Radiation and Tumor Biology, Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine. 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan [2] Group of Radiation and Tumor Biology, Career-Path Promotion Unit for Young Life Scientists, Kyoto University. Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

Efficacy of salvage stereotactic radiotherapy for recurrent glioma: impact of tumor morphology and method of target delineation on local control.
Cancer Med 2013 Dec 28;2(6):942-9. Epub 2013 Oct 28.
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, 54 Kawahara-cho Shogoin Sakyo-ku, Kyoto, 606-8507, Japan.

Initial and cumulative recurrence patterns of glioblastoma after temozolomide-based chemoradiotherapy and salvage treatment: a retrospective cohort study in a single institution.
Radiat Oncol 2013 Apr 23;8:97. Epub 2013 Apr 23.
Departments of Radiation Oncology and Image-applied Therapy, 54 Kawahara-cho, Shogoin Sakyo-ku, Kyoto 606-8507, Japan.


Pretreatment C-reactive protein level predicts outcome and patterns of failure after chemoradiotherapy for locally advanced pancreatic cancer.
Pancreatology 2015 Nov-Dec;15(6):694-700. Epub 2015 Oct 14.
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan.

LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis.
Oncotarget 2016 10;7(40):65837-65848
Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan.



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