Publications

Inter- and Intrafractional Variation in the 3-Dimensional Positions of Pancreatic Tumors Due to Respiration Under Real-Time Monitoring.
Int J Radiat Oncol Biol Phys 2017 Aug 31;98(5):1204-1211. Epub 2017 Mar 31.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Long-term outcomes of intensity-modulated radiotherapy following extra-pleural pneumonectomy for malignant pleural mesothelioma.
Acta Oncol 2017 Jul 24;56(7):957-962. Epub 2017 Jan 24.
a Department of Radiation Oncology and Image-applied Therapy , Graduate School of Medicine, Kyoto University , Kyoto , Japan.

Three-dimensional intrafractional internal target motions in accelerated partial breast irradiation using three-dimensional conformal external beam radiotherapy.
Radiother Oncol 2017 Jul 19;124(1):118-123. Epub 2017 May 19.
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto University, Japan.


Decreased acute toxicities of intensity-modulated radiation therapy for localized prostate cancer with prostate-based versus bone-based image guidance.
Int J Clin Oncol 2017 Jul 29. Epub 2017 Jul 29.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.


UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization.
Sci Rep 2017 Jul 31;7(1):6879. Epub 2017 Jul 31.
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Development of a four-dimensional Monte Carlo dose calculation system for real-time tumor-tracking irradiation with a gimbaled X-ray head.
Phys Med 2017 Mar 16;35:59-65. Epub 2017 Feb 16.
Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan.


Regional recurrence in breast cancer patients with one to three positive axillary lymph nodes treated with breast-conserving surgery and whole breast irradiation.
J Radiat Res 2017 Jan 15;58(1):79-85. Epub 2016 Jul 15.
Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto 606-8507, Japan.


Feasibility evaluation of hypofractionated radiotherapy with concurrent temozolomide in elderly patients with glioblastoma.
Int J Clin Oncol 2016 Dec 6;21(6):1023-1029. Epub 2016 Jul 6.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.



Identification of a predictive factor for distant metastasis in esophageal squamous cell carcinoma after definitive chemoradiotherapy.
Int J Clin Oncol 2016 Oct 2;21(5):899-908. Epub 2016 Mar 2.
Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, 54 Sho-goin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.


Ten-year outcomes of intensity-modulated radiation therapy combined with neoadjuvant hormonal therapy for intermediate- and high-risk patients with T1c-T2N0M0 prostate cancer.
Int J Clin Oncol 2016 Aug 3;21(4):783-90. Epub 2016 Feb 3.
Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.



Non-coplanar volumetric-modulated arc therapy (VMAT) for craniopharyngiomas reduces radiation doses to the bilateral hippocampus: a planning study comparing dynamic conformal arc therapy, coplanar VMAT, and non-coplanar VMAT.
Radiat Oncol 2016 Jun 23;11:86. Epub 2016 Jun 23.
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Initial characterization, dosimetric benchmark and performance validation of Dynamic Wave Arc.
Radiat Oncol 2016 Apr 29;11:63. Epub 2016 Apr 29.
Department of Radiotherapy, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Laarbeeklaan 101, B-1090, Brussels, Belgium.

Long-term outcomes of intensity-modulated radiation therapy combined with neoadjuvant androgen deprivation therapy under an early salvage policy for patients with T3-T4N0M0 prostate cancer.
Int J Clin Oncol 2016 Feb 4;21(1):148-55. Epub 2015 Jul 4.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Clinical effect of multileaf collimator width on the incidence of late rectal bleeding after high-dose intensity-modulated radiotherapy for localized prostate carcinoma.
Int J Clin Oncol 2016 Feb 12;21(1):156-61. Epub 2015 Jul 12.
Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

L-Phenylalanine preloading reduces the (10)B(n, α)(7)Li dose to the normal brain by inhibiting the uptake of boronophenylalanine in boron neutron capture therapy for brain tumours.
Cancer Lett 2016 Jan 8;370(1):27-32. Epub 2015 Oct 8.
Department of Nuclear Science and Engineering, Kyoto University Research Reactor Institute, Osaka 590-0494, Japan. Electronic address:

Target localization errors from fiducial markers implanted around a lung tumor for dynamic tumor tracking.
Phys Med 2015 Dec 10;31(8):934-41. Epub 2015 Jul 10.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, Japan.



Pretreatment C-reactive protein level predicts outcome and patterns of failure after chemoradiotherapy for locally advanced pancreatic cancer.
Pancreatology 2015 Nov-Dec;15(6):694-700. Epub 2015 Oct 14.
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan.


Dose calculation accuracies in whole breast radiotherapy treatment planning: a multi-institutional study.
Radiol Phys Technol 2015 Jul 3;8(2):200-8. Epub 2015 Feb 3.
Department of Radiation Oncology, Saitama Medical University Saitama Medical Center, 1981, Kamoda, Kawagoe City, Saitama, 350-8550, Japan,

Radiation sensitivity assay with a panel of patient-derived spheroids of small cell carcinoma of the cervix.
Int J Cancer 2015 Jun 11;136(12):2949-60. Epub 2014 Dec 11.
Department of Biochemistry, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan; Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, Kyoto, Japan.



Impact of pretreatment interstitial lung disease on radiation pneumonitis and survival after stereotactic body radiation therapy for lung cancer.
J Thorac Oncol 2015 Jan;10(1):116-25
*Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, Kyoto, Japan; †Department of Genome Biology, Kinki University Faculty of Medicine, Osaka-Sayama, Japan; ‡Departments of Respiratory Medicine, and §Diagnostic Imaging and Nuclear Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan; and ‖Department of Therapeutic Radiology, Yamaguchi University Graduate School of Medicine, Ube, Japan.

UCHL1 provides diagnostic and antimetastatic strategies due to its deubiquitinating effect on HIF-1α.
Nat Commun 2015 Jan 23;6:6153. Epub 2015 Jan 23.
1] Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Kyoto 606-8507, Japan [2] Group of Radiation and Tumor Biology, Career-Path Promotion Unit for Young Life Scientists, Kyoto University, Yoshida Konoe-cho, Kyoto 606-8501, Japan [3] Precursory Research for Embryonic Science and Technology (PRESTO), Japan Science and Technology Agency (JST), 4-1-8 Honcho, Saitama 332-0012, Japan.

Dosimetric shield evaluation with tungsten sheet in 4, 6, and 9MeV electron beams.
Phys Med 2014 Nov 19;30(7):838-42. Epub 2014 Jun 19.
Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, 54 Kawara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.


Safety and effectiveness of stereotactic body radiotherapy for a clinically diagnosed primary stage I lung cancer without pathological confirmation.
Int J Clin Oncol 2014 Oct 12;19(5):814-21. Epub 2013 Nov 12.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin, Kawahara-cho, Sakyo-ku, Kyoto, Kyoto, Japan.

The impact of abdominal compression on outcome in patients treated with stereotactic body radiotherapy for primary lung cancer.
J Radiat Res 2014 Sep 6;55(5):934-9. Epub 2014 May 6.
Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.



Radiotherapy for patients with isolated local recurrence of primary resected pancreatic cancer. Prolonged disease-free interval associated with favorable prognosis.
Strahlenther Onkol 2014 May 6;190(5):485-90. Epub 2014 Mar 6.
Department of Radiation Oncology and Image-Applied Therapy, Graduate School of Medicine, Kyoto University, 606-8507, Kyoto, Japan,


Long-term outcomes of dynamic conformal arc irradiation combined with neoadjuvant hormonal therapy in Japanese patients with T1c-T2N0M0 prostate cancer: case series study.
Jpn J Clin Oncol 2014 Feb 29;44(2):180-5. Epub 2013 Dec 29.
*Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.

HIF-1-mediated metabolic reprogramming reduces ROS levels and facilitates the metastatic colonization of cancers in lungs.
Sci Rep 2014 Jan 23;4:3793. Epub 2014 Jan 23.
1] Group of Radiation and Tumor Biology, Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine. 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan [2] Group of Radiation and Tumor Biology, Career-Path Promotion Unit for Young Life Scientists, Kyoto University. Yoshida Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan.

Efficacy of salvage stereotactic radiotherapy for recurrent glioma: impact of tumor morphology and method of target delineation on local control.
Cancer Med 2013 Dec 28;2(6):942-9. Epub 2013 Oct 28.
Department of Radiation Oncology and Image-applied Therapy, Kyoto University Graduate School of Medicine, 54 Kawahara-cho Shogoin Sakyo-ku, Kyoto, 606-8507, Japan.

Initial and cumulative recurrence patterns of glioblastoma after temozolomide-based chemoradiotherapy and salvage treatment: a retrospective cohort study in a single institution.
Radiat Oncol 2013 Apr 23;8:97. Epub 2013 Apr 23.
Departments of Radiation Oncology and Image-applied Therapy, 54 Kawahara-cho, Shogoin Sakyo-ku, Kyoto 606-8507, Japan.

LY6E: a conductor of malignant tumor growth through modulation of the PTEN/PI3K/Akt/HIF-1 axis.
Oncotarget 2016 10;7(40):65837-65848
Department of Radiation Oncology and Image-Applied Therapy, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan.

OF