Maryam Fouladi

Maryam Fouladi

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Maryam Fouladi

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A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.

Cancer Cell 2019 Jul;36(1):51-67.e7

Arthur and Sonia Labatt Brain Tumor Research Centre, Division of Haematology/Oncology, Hospital for Sick Children, Toronto, ON M5G0A4, Canada; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S1A8, Canada; Division of Hematology-Oncology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON M5G1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.06.002DOI Listing
July 2019

Hypothalamic-pituitary function following childhood brain tumors: Analysis of prospective annual endocrine screening.

Pediatr Blood Cancer 2019 05 28;66(5):e27631. Epub 2019 Jan 28.

Divisions of Pediatric Endocrinology, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, Ohio.

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http://dx.doi.org/10.1002/pbc.27631DOI Listing
May 2019

Management of pediatric low-grade glioma.

Curr Opin Pediatr 2019 02;31(1):21-27

Division of Oncology, Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta.

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http://Insights.ovid.com/crossref?an=00008480-900000000-9891
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http://dx.doi.org/10.1097/MOP.0000000000000717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664811PMC
February 2019

Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial.

J Clin Oncol 2018 Oct 17:JCO2017764720. Epub 2018 Oct 17.

Eugene I. Hwang and Roger J. Packer, Children's National Medical Center, Washington, DC; Marcel Kool, Lukas Chavez, Sebastian Brabetz, David T.W. Jones, and Stefan M. Pfister, German Cancer Research Center; David Capper, Andreas von Deimling, and Stefan M. Pfister, University Hospital Heidelberg; Stefan M. Pfister, National Center for Tumor Diseases, Heidelberg; David Capper, Charité Medical University, Berlin, Germany; Peter C. Burger, Johns Hopkins University, Baltimore, MD; Chris Williams-Hughes, Children's Oncology Group, Littleton, CO; Catherine Billups, Yimei Li, and Amar Gajjar, St Jude Children's Research Hospital, Memphis, TN; Linda Heier, Weill Cornell Medical College, New York, NY; Alok Jaju, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Jeff Michalski, Washington University School of Medicine, St. Louis, MO; Sarah Leary and James M. Olson, Seattle Children's Hospital and Research Institute; Sarah Leary and James M. Olson, Fred Hutchinson Cancer Research Center, Seattle, WA; Tianni Zhou, California State University, Long Beach, Long Beach, CA; Maryam Fouladi, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; and Ian F. Pollack, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1200/JCO.2017.76.4720DOI Listing
October 2018

Induced Telomere Damage to Treat Telomerase Expressing Therapy-Resistant Pediatric Brain Tumors.

Mol Cancer Ther 2018 07 13;17(7):1504-1514. Epub 2018 Apr 13.

Brain Tumor Center, Division of Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://mct.aacrjournals.org/lookup/doi/10.1158/1535-7163.MCT
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http://dx.doi.org/10.1158/1535-7163.MCT-17-0792DOI Listing
July 2018

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

J Clin Oncol 2018 07 10;36(19):1963-1972. Epub 2018 May 10.

Lindsey M. Hoffman and Nicholas K. Foreman, University of Colorado Denver; Lindsey M. Hoffman and Nicholas K. Foreman, Children's Hospital Colorado, Aurora, CO; Sophie E.M. Veldhuijzen van Zanten, Esther Hulleman, Gertjan J.L. Kaspers, Esther Sanchez, and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; William P. Vandertop, Academy of Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Niclas Colditz, Marion Hoffmann, Brigitte Bison, Monika Warmuth-Metz, and Christof M. Kramm, University Medical Center Goettingen, Goettingen; Torsten Pietsch and Gerrit H. Gielen, University of Bonn Medical Center, Bonn; David T.W. Jones, Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, German Cancer Research Center, Hopp-Children's Cancer Center at the Nationale Centrum für Tumorerkrankungen Heidelberg, and German Consortium for Translational Cancer Research; Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, Heidelberg University Hospital, Heidelberg, Germany; Joshua Baugh, Brooklyn Chaney, Adam Lane, Christine Fuller, Nancy Yanez Escorza, Renee Doughman, Rachid Drissi, James Leach, Blaise Jones, and Maryam Fouladi, Cincinnati Children's Hospital Medical Center, Cincinnati; Emmett Broxson, Wright State University and The Children's Medical Center, Dayton, OH; Lili Miles, Nemours Children's Hospital, Orlando, FL; Cynthia Hawkins, Ute Bartels, and Eric Bouffet, The Hospital for Sick Children, Toronto, Ontario; Anne Sophie Carret, Centre Hospitalier Universitaire Sainte-Justine; Nada Jabado, McGill University, Montreal, Quebec, Canada; Stewart Goldman, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL; Sarah Leary, Seattle Children's Hospital, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA; Roger Packer, Children's National Health System; Javad Nazarian, Children's National Medical Center, Washington, DC; Katherine E. Warren, National Cancer Institute, Bethesda, MD; Alberto Broniscer, St Jude Children's Research Hospital, Memphis, TN; Mark W. Kieran, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA; Jane Minturn, Children's Hospital of Philadelphia and The Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Melanie Comito, The Pennsylvania State University, Hershey, PA; Chie-Schin Shih, Indiana University, Indianapolis, IN; Soumen Khatua, The University of Texas MD Anderson Cancer Center; Murali Chintagumpala, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX; Timothy Hassall, Lady Cilento Children's Hospital, Brisbane, Queensland; David S. Ziegler, Kids Cancer Centre, Sydney Children's Hospital, Randwick; David S. Ziegler, University of New South Wales, Sydney, New South Wales; Nicholas Gottardo and Hetal Dholaria, Princess Margaret Hospital for Children, Perth, Western Australia, Australia; Martin Benesch, Medical University of Graz, Graz, Austria; Nathalie Boddaert. Stephanie Puget, and Raphaël Calmon, Hôpital Necker Enfants Malades; Pascale Varlet, Hôpital Sainte-Anne, Université Paris V Descartes, Sorbonne Paris Cité, Paris; Géraldine Giraud, David Castel, and Jacques Grill, Gustave Roussy, Université Paris-Sud, Université Paris-Saclay, Villejuif, France; Géraldine Giraud, Uppsala University, Uppsala, Sweden; Chris Jones, The Institute of Cancer Research, Sutton; Darren Hargrave, Great Ormond Street Hospital, London; Guirish A. Solanki, Birmingham Women's and Children's Hospital, Birmingham; Simon Bailey, Great North Children's Hospital, Victoria Wing, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom; Piergiorgio Modena and Marzia Giagnacovo, Sant' Anna Como General Hospital, Como; Manila Antonelli, Sapienza University of Rome, Rome; Veronica Biassoni and Maura Massimino, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan, Italy; Nicolas U. Gerber and Michael A. Grotzer, University Children's Hospital of Zurich, Zurich; André O. von Bueren, University Hospital of Geneva and University of Geneva, Geneva, Switzerland; and Filip Jadrijevic Cvrlje and Gertjan J.L. Kaspers, Children's Hospital Zagreb, Zagreb, Croatia.

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http://dx.doi.org/10.1200/JCO.2017.75.9308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075859PMC
July 2018

Regulatory T cell subsets in patients with medulloblastoma at diagnosis and during standard irradiation and chemotherapy (PBTC N-11).

Cancer Immunol Immunother 2017 Dec 20;66(12):1589-1595. Epub 2017 Aug 20.

The Preston A. Wells Center for Brain Tumor Therapy, McKnight Brain Institute, University of Florida, Room L1-183, Gainesville, FL, 32608, USA.

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http://dx.doi.org/10.1007/s00262-017-2051-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5677543PMC
December 2017

Contemporary survival endpoints: an International Diffuse Intrinsic Pontine Glioma Registry study.

Neuro Oncol 2017 09;19(9):1279-1280

Departments of Neurology, Neurosurgery and Pediatrics, Lucile Packard Children's Hospital at Stanford, Stanford, California; Department of Pediatrics, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Division of Hematology/Oncology, The Hospital for Sick Children, Toronto, Canada; Departments of Hematology-Oncology, Neuro-Oncology & Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois; Department of Hematology/Oncology, Seattle Children's Hospital, Seattle, Washington; Departments of Pediatrics, University of Colorado and Morgan Adams Foundation Pediatric Brain Tumor Research Program, Children's Hospital Colorado, Denver, Colorado; Center for Neuroscience and Behavioral Medicine, Children's National Medical Center, Washington D.C.; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Section of Pediatric Hematology/Oncology, Riley Children's Hospital, Indianapolis, Indiana; Department of Pediatrics, Texas Children's Hospital, Houston, Texas; Lady Cilento Children's Hospital, Brisbane, Australia; Princess Margaret Hospital for Children and Telethon Kid's Institute, Subiaco, Australia; Pediatric Oncology Branch, National Cancer Institute, Bethesda, Maryland.

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http://dx.doi.org/10.1093/neuonc/nox107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570207PMC
September 2017

BMI-1 is a potential therapeutic target in diffuse intrinsic pontine glioma.

Oncotarget 2017 Sep 19;8(38):62962-62975. Epub 2017 May 19.

Brain Tumor Center, Division of Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.18632/oncotarget.18002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609895PMC
September 2017

The transcription factor Olig2 is important for the biology of diffuse intrinsic pontine gliomas.

Neuro Oncol 2017 08;19(8):1068-1078

Division of Oncology (J.L.A., R.M., N.O., A.L., S.S., R.D., M.F., L.M.C., L.H., M.D., B.D.), Experimental Hematology and Cancer Biology (R.R.W., J.W.), Pathology (L.M.), Developmental Biology, Center for Autoimmune Genomics and Etiology and Biomedical Informatics, Cincinnati Childrens Hospital Medical Center (CCHMC), Cincinnati, Ohio (M.L.W.); Division of Pediatric Oncology, Johns Hopkins University, Baltimore, Maryland (E.H.R.), Nemours Children’s Hospital, Orlando, Florida (L.M.)

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http://dx.doi.org/10.1093/neuonc/now299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570182PMC
August 2017

A phase I trial of the MEK inhibitor selumetinib (AZD6244) in pediatric patients with recurrent or refractory low-grade glioma: a Pediatric Brain Tumor Consortium (PBTC) study.

Neuro Oncol 2017 Aug;19(8):1135-1144

University of California San Francisco, San Francisco, California; Boston Children's Hospital, Boston, Massachusetts; Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania; St Jude Children's Research Hospital, Memphis, Tennessee; Lurie Children's Hospital, Chicago, Illinois; Children's National Medical Center, Washington, DC; Duke University Medical Center, Durham, North Carolina; Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, Maryland; Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1093/neuonc/now282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570236PMC
August 2017

Random-effects meta-analysis for systematic reviews of phase I clinical trials: Rare events and missing data.

Res Synth Methods 2017 Jun 10;8(2):124-135. Epub 2016 Jun 10.

Department of Mathematical Sciences, University of Cincinnati, Cincinnati, OH, 45221, USA.

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http://dx.doi.org/10.1002/jrsm.1209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149121PMC
June 2017

MEK and RAF inhibitors: time for a paradigm shift in the treatment of pediatric low-grade gliomas?

Neuro Oncol 2017 06;19(6):741-743

Division of Pediatric Neuro-oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1093/neuonc/nox039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464452PMC
June 2017

Intertumoral Heterogeneity within Medulloblastoma Subgroups.

Authors:
Florence M G Cavalli Marc Remke Ladislav Rampasek John Peacock David J H Shih Betty Luu Livia Garzia Jonathon Torchia Carolina Nor A Sorana Morrissy Sameer Agnihotri Yuan Yao Thompson Claudia M Kuzan-Fischer Hamza Farooq Keren Isaev Craig Daniels Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Ji Yeoun Lee Wieslawa A Grajkowska Marta Perek-Polnik Alexandre Vasiljevic Cecile Faure-Conter Anne Jouvet Caterina Giannini Amulya A Nageswara Rao Kay Ka Wai Li Ho-Keung Ng Charles G Eberhart Ian F Pollack Ronald L Hamilton G Yancey Gillespie James M Olson Sarah Leary William A Weiss Boleslaw Lach Lola B Chambless Reid C Thompson Michael K Cooper Rajeev Vibhakar Peter Hauser Marie-Lise C van Veelen Johan M Kros Pim J French Young Shin Ra Toshihiro Kumabe Enrique López-Aguilar Karel Zitterbart Jaroslav Sterba Gaetano Finocchiaro Maura Massimino Erwin G Van Meir Satoru Osuka Tomoko Shofuda Almos Klekner Massimo Zollo Jeffrey R Leonard Joshua B Rubin Nada Jabado Steffen Albrecht Jaume Mora Timothy E Van Meter Shin Jung Andrew S Moore Andrew R Hallahan Jennifer A Chan Daniela P C Tirapelli Carlos G Carlotti Maryam Fouladi José Pimentel Claudia C Faria Ali G Saad Luca Massimi Linda M Liau Helen Wheeler Hideo Nakamura Samer K Elbabaa Mario Perezpeña-Diazconti Fernando Chico Ponce de León Shenandoah Robinson Michal Zapotocky Alvaro Lassaletta Annie Huang Cynthia E Hawkins Uri Tabori Eric Bouffet Ute Bartels Peter B Dirks James T Rutka Gary D Bader Jüri Reimand Anna Goldenberg Vijay Ramaswamy Michael D Taylor

Cancer Cell 2017 06;31(6):737-754.e6

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163053PMC
June 2017

Population pharmacokinetics of temsirolimus and sirolimus in children with recurrent solid tumours: a report from the Children's Oncology Group.

Br J Clin Pharmacol 2017 05 20;83(5):1097-1107. Epub 2016 Dec 20.

Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

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http://dx.doi.org/10.1111/bcp.13181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401981PMC
May 2017

Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease.

J Neurooncol 2017 04 21;132(2):255-266. Epub 2017 Jan 21.

Department of Paediatrics, Division of Oncology/Haematology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11060-016-2363-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378734PMC
April 2017

A comparison of safety and efficacy of cytotoxic versus molecularly targeted drugs in pediatric phase I solid tumor oncology trials.

Pediatr Blood Cancer 2017 03 22;64(3). Epub 2016 Sep 22.

Division of Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

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http://dx.doi.org/10.1002/pbc.26258DOI Listing
March 2017

Radiation and subsequent reirradiation outcomes in the treatment of diffuse intrinsic pontine glioma and a systematic review of the reirradiation literature.

Pract Radiat Oncol 2017 Mar - Apr;7(2):86-92. Epub 2016 Nov 23.

Department of Radiation Oncology, University of Cincinnati Barrett Cancer Center, Cincinnati, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.prro.2016.11.005DOI Listing
March 2017

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Authors:
Jonathon Torchia Brian Golbourn Shengrui Feng King Ching Ho Patrick Sin-Chan Alexandre Vasiljevic Joseph D Norman Paul Guilhamon Livia Garzia Natalia R Agamez Mei Lu Tiffany S Chan Daniel Picard Pasqualino de Antonellis Dong-Anh Khuong-Quang Aline C Planello Constanze Zeller Dalia Barsyte-Lovejoy Lucie Lafay-Cousin Louis Letourneau Mathieu Bourgey Man Yu Deena M A Gendoo Misko Dzamba Mark Barszczyk Tiago Medina Alexandra N Riemenschneider A Sorana Morrissy Young-Shin Ra Vijay Ramaswamy Marc Remke Christopher P Dunham Stephen Yip Ho-Keung Ng Jian-Qiang Lu Vivek Mehta Steffen Albrecht Jose Pimentel Jennifer A Chan Gino R Somers Claudia C Faria Lucia Roque Maryam Fouladi Lindsey M Hoffman Andrew S Moore Yin Wang Seung Ah Choi Jordan R Hansford Daniel Catchpoole Diane K Birks Nicholas K Foreman Doug Strother Almos Klekner Laszló Bognár Miklós Garami Péter Hauser Tibor Hortobágyi Beverly Wilson Juliette Hukin Anne-Sophie Carret Timothy E Van Meter Eugene I Hwang Amar Gajjar Shih-Hwa Chiou Hideo Nakamura Helen Toledano Iris Fried Daniel Fults Takafumi Wataya Chris Fryer David D Eisenstat Katrin Scheinemann Adam J Fleming Donna L Johnston Jean Michaud Shayna Zelcer Robert Hammond Samina Afzal David A Ramsay Nongnuch Sirachainan Suradej Hongeng Noppadol Larbcharoensub Richard G Grundy Rishi R Lulla Jason R Fangusaro Harriet Druker Ute Bartels Ronald Grant David Malkin C Jane McGlade Theodore Nicolaides Tarik Tihan Joanna Phillips Jacek Majewski Alexandre Montpetit Guillaume Bourque Gary D Bader Alyssa T Reddy G Yancey Gillespie Monika Warmuth-Metz Stefan Rutkowski Uri Tabori Mathieu Lupien Michael Brudno Ulrich Schüller Torsten Pietsch Alexander R Judkins Cynthia E Hawkins Eric Bouffet Seung-Ki Kim Peter B Dirks Michael D Taylor Anat Erdreich-Epstein Cheryl H Arrowsmith Daniel D De Carvalho James T Rutka Nada Jabado Annie Huang

Cancer Cell 2016 Dec;30(6):891-908

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Paediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Division of Hematology/Oncology, Hospital for Sick Children, Toronto, ON M5G1X8, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON M5G1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500911PMC
December 2016

Phase I trial of p28 (NSC745104), a non-HDM2-mediated peptide inhibitor of p53 ubiquitination in pediatric patients with recurrent or progressive central nervous system tumors: A Pediatric Brain Tumor Consortium Study.

Neuro Oncol 2016 09 28;18(9):1319-25. Epub 2016 Mar 28.

Division of Hematology, Oncology, Neuro-Oncology and Stem Cell Transplant, Ann & Robert H. Lurie Children's Hospital of Chicago and Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois (R.R.L., S.G.); Division of Surgical Oncology, Department of Surgery, University of Illinois College of Medicine, Chicago, Illinois (T.Y., C.W.B.); Pharmacy Investigational Drug Service, University of Illinois Hospital and Health Sciences System, University of Illinois College of Pharmacy, Chicago, Illinois (L.B., M.P.); Department of Neurosurgery, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania (I.F.P.); Departments of Neurology, Pediatrics, Neurosurgery, and Human Biology, Stanford University, Palo Alto, California (P.G.F.); Center for Neuroscience and Behavioral Medicine, Brain Tumor Institute, Children's National Health System, Department of Neurology and Pediatrics, The George Washington University, Washington, DC (R.J.P.); Memorial Sloan Kettering Cancer Center, Department of Pediatrics, Weill Cornell Medical College, New York, New York (I.J.D.); Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine of University of Southern California, Los Angeles, California (G.D.); Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, Tennessee (S.W., A.O., J.M.B.); Department of Hematology-Oncology, Cincinnati Children's Hospital Medical Center, Neuro-Oncology Program, Cincinnati, Ohio (M.F.).

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http://dx.doi.org/10.1093/neuonc/now047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999001PMC
September 2016

Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.

Authors:
Vijay Ramaswamy Thomas Hielscher Stephen C Mack Alvaro Lassaletta Tong Lin Kristian W Pajtler David T W Jones Betty Luu Florence M G Cavalli Kenneth Aldape Marc Remke Martin Mynarek Stefan Rutkowski Sridharan Gururangan Roger E McLendon Eric S Lipp Christopher Dunham Juliette Hukin David D Eisenstat Dorcas Fulton Frank K H van Landeghem Mariarita Santi Marie-Lise C van Veelen Erwin G Van Meir Satoru Osuka Xing Fan Karin M Muraszko Daniela P C Tirapelli Sueli M Oba-Shinjo Suely K N Marie Carlos G Carlotti Ji Yeoun Lee Amulya A Nageswara Rao Caterina Giannini Claudia C Faria Sofia Nunes Jaume Mora Ronald L Hamilton Peter Hauser Nada Jabado Kevin Petrecca Shin Jung Luca Massimi Massimo Zollo Giuseppe Cinalli László Bognár Almos Klekner Tibor Hortobágyi Sarah Leary Ralph P Ermoian James M Olson Jeffrey R Leonard Corrine Gardner Wieslawa A Grajkowska Lola B Chambless Jason Cain Charles G Eberhart Sama Ahsan Maura Massimino Felice Giangaspero Francesca R Buttarelli Roger J Packer Lyndsey Emery William H Yong Horacio Soto Linda M Liau Richard Everson Andrew Grossbach Tarek Shalaby Michael Grotzer Matthias A Karajannis David Zagzag Helen Wheeler Katja von Hoff Marta M Alonso Teresa Tuñon Ulrich Schüller Karel Zitterbart Jaroslav Sterba Jennifer A Chan Miguel Guzman Samer K Elbabaa Howard Colman Girish Dhall Paul G Fisher Maryam Fouladi Amar Gajjar Stewart Goldman Eugene Hwang Marcel Kool Harshad Ladha Elizabeth Vera-Bolanos Khalida Wani Frank Lieberman Tom Mikkelsen Antonio M Omuro Ian F Pollack Michael Prados H Ian Robins Riccardo Soffietti Jing Wu Phillipe Metellus Uri Tabori Ute Bartels Eric Bouffet Cynthia E Hawkins James T Rutka Peter Dirks Stefan M Pfister Thomas E Merchant Mark R Gilbert Terri S Armstrong Andrey Korshunov David W Ellison Michael D Taylor

J Clin Oncol 2016 07 6;34(21):2468-77. Epub 2016 Jun 6.

Vijay Ramaswamy, Stephen C. Mack, Alvaro Lassaletta, Betty Luu, Florence M.G. Cavalli, Uri Tabori, Ute Bartels, Eric Bouffet, Cynthia E. Hawkins, James T. Rutka, Peter Dirks, and Michael D. Taylor, The Hospital for Sick Children; Vijay Ramaswamy, Kenneth Aldape, James T. Rutka, and Michael D. Taylor, University of Toronto; Kenneth Aldape, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario; Christopher Dunham and Juliette Hukin, British Columbia Children's Hospital; Juliette Hukin, University of British Columbia, Vancouver, British Columbia; David D. Eisenstat, Dorcas Fulton, and Frank K.H. van Landeghem, University of Alberta, Edmonton; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Nada Jabado and Kevin Petrecca, McGill University, Montreal, Quebec, Canada; Thomas Hielscher, Kristian W. Pajtler, David T.W. Jones, Marcel Kool, Stefan M. Pfister, and Andrey Korshunov, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Marc Remke, University Hospital Düsseldorf, Düsseldorf; Martin Mynarek, Stefan Rutkowski, and Katja von Hoff, University Medical Center Hamburg-Eppendorf, Hamburg; Ulrich Schüller, Ludwig-Maximilians-Universität, Munich, Germany; Stephen C. Mack, Cleveland Clinic Foundation, Cleveland; Maryam Fouladi, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Tong Lin, Amar Gajjar, Thomas E. Merchant, and David W. Ellison, St Jude Children's Research Hospital, Memphis; Lola B. Chambless, Vanderbilt Medical Center, Nashville, TN; Sridharan Gururangan, Roger E. McLendon, and Eric S. Lipp, Duke University, Durham; Jing Wu, University of North Carolina at Chapel Hill, Chapel Hill, NC; Mariarita Santi, Children's Hospital of Philadelphia; Lyndsey Emery, Hospital of the University of Pennsylvania, Philadelphia; Ronald L. Hamilton and Ian F. Pollack, University of Pittsburgh School of Medicine; Frank Lieberman, University of Pittsburgh Medical Cen

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http://dx.doi.org/10.1200/JCO.2015.65.7825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4962737PMC
July 2016

Apparent diffusion coefficient histogram metrics correlate with survival in diffuse intrinsic pontine glioma: a report from the Pediatric Brain Tumor Consortium.

Neuro Oncol 2016 05 20;18(5):725-34. Epub 2015 Oct 20.

Department of Radiology, Boston Children's Hospital, Boston, Massachusetts (T.Y.P., S.V., K.I.R.); Department of Radiology, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (A.P.); Department of Diagnostic Imaging, St Jude Children's Research Hospital, Memphis, Tennessee (L.E.K.); Department of Biostatistics, St Jude Children's Research Hospital, Memphis, Tennessee (M.K., J.M.B.); Department of Neurosurgery, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania (I.F.P.); Neuro-Oncology Program, Cincinnati Children's Hospital, Cincinnati, Ohio (M.F.).

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http://dx.doi.org/10.1093/neuonc/nov256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4827042PMC
May 2016

Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma.

Cancer Cell 2016 05;29(5):669-683

Department of Pediatrics, Division of Experimental Hematology and Cancer Biology, Brain Tumor Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 25229, USA; Key Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai 201102, China. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946168PMC
May 2016

A pilot study of bevacizumab-based therapy in patients with newly diagnosed high-grade gliomas and diffuse intrinsic pontine gliomas.

J Neurooncol 2016 Mar 1;127(1):53-61. Epub 2015 Dec 1.

Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave MLC 7051, Cincinnati, OH, 45229, USA.

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March 2016

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.

Authors:
Dominik Sturm Brent A Orr Umut H Toprak Volker Hovestadt David T W Jones David Capper Martin Sill Ivo Buchhalter Paul A Northcott Irina Leis Marina Ryzhova Christian Koelsche Elke Pfaff Sariah J Allen Gnanaprakash Balasubramanian Barbara C Worst Kristian W Pajtler Sebastian Brabetz Pascal D Johann Felix Sahm Jüri Reimand Alan Mackay Diana M Carvalho Marc Remke Joanna J Phillips Arie Perry Cynthia Cowdrey Rachid Drissi Maryam Fouladi Felice Giangaspero Maria Łastowska Wiesława Grajkowska Wolfram Scheurlen Torsten Pietsch Christian Hagel Johannes Gojo Daniela Lötsch Walter Berger Irene Slavc Christine Haberler Anne Jouvet Stefan Holm Silvia Hofer Marco Prinz Catherine Keohane Iris Fried Christian Mawrin David Scheie Bret C Mobley Matthew J Schniederjan Mariarita Santi Anna M Buccoliero Sonika Dahiya Christof M Kramm André O von Bueren Katja von Hoff Stefan Rutkowski Christel Herold-Mende Michael C Frühwald Till Milde Martin Hasselblatt Pieter Wesseling Jochen Rößler Ulrich Schüller Martin Ebinger Jens Schittenhelm Stephan Frank Rainer Grobholz Istvan Vajtai Volkmar Hans Reinhard Schneppenheim Karel Zitterbart V Peter Collins Eleonora Aronica Pascale Varlet Stephanie Puget Christelle Dufour Jacques Grill Dominique Figarella-Branger Marietta Wolter Martin U Schuhmann Tarek Shalaby Michael Grotzer Timothy van Meter Camelia-Maria Monoranu Jörg Felsberg Guido Reifenberger Matija Snuderl Lynn Ann Forrester Jan Koster Rogier Versteeg Richard Volckmann Peter van Sluis Stephan Wolf Tom Mikkelsen Amar Gajjar Kenneth Aldape Andrew S Moore Michael D Taylor Chris Jones Nada Jabado Matthias A Karajannis Roland Eils Matthias Schlesner Peter Lichter Andreas von Deimling Stefan M Pfister David W Ellison Andrey Korshunov Marcel Kool

Cell 2016 Feb;164(5):1060-1072

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.

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February 2016

Vismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.

J Clin Oncol 2015 Aug 13;33(24):2646-54. Epub 2015 Jul 13.

Giles W. Robinson, Brent A. Orr, Gang Wu, Tong Lin, Ibrahim Qaddoumi, Sue C. Kaste, Michael Rusch, Sariah J. Allen, Arzu Onar-Thomas, Clinton F. Stewart, James M. Boyett, Richard J. Gilbertson, David W. Ellison, and Amar Gajjar, St Jude Children's Research Hospital, Memphis, TN; Sridharan Gururangan and Annick Desjardins, Duke University Medical Center, Durham, NC; Roger J. Packer, Children's National Medical Center, Washington, DC; Stewart Goldman, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Michael D. Prados, University of California San Francisco, San Francisco, CA; Murali Chintagumpala, Texas Children's Cancer Center, Houston, TX; Naoko Takebe, National Cancer Institute, Bethesda, MD; Maryam Fouladi, Cincinnati Children's Hospital, Cincinnati, OH; and Tom Curran, Children's Hospital of Philadelphia, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.2014.60.1591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534527PMC
August 2015

Nocardia farcinica Meningitis Masquerading as Central Nervous System Metastasis in a Child With Cerebellar Pilocytic Astrocytoma.

J Pediatr Hematol Oncol 2015 Aug;37(6):482-5

Divisions of *Oncology, Cancer and Blood Diseases Institute ∥Pediatric Neurosurgery Departments of ‡Pediatrics, Division of Infectious Diseases §Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH †Department of Pediatrics, Division of Infectious Diseases, University of Illinois at Chicago, Chicago, IL.

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August 2015

Towards risk-adapted therapy for rhabdoid tumour subgroups.

Lancet Oncol 2015 May 14;16(5):486-8. Epub 2015 Apr 14.

Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. Electronic address:

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May 2015

Molecular biology of pediatric brain tumors and impact on novel therapies.

Curr Neurol Neurosci Rep 2015 Apr;15(4):10

Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, USA,

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April 2015

Tumor-associated macrophages in SHH subgroup of medulloblastomas.

Clin Cancer Res 2015 Mar 24;21(6):1457-65. Epub 2014 Oct 24.

Children's Hospital Los Angeles and The Saban Research Institute, Los Angeles, California. Department of Pediatrics, Keck School of Medicine of University of Southern California, Los Angeles, California. Department of Pathology, Keck School of Medicine of University of Southern California, Los Angeles, California.

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March 2015

Population pharmacokinetic analysis of oxaliplatin in adults and children identifies important covariates for dosing.

Cancer Chemother Pharmacol 2015 Mar 4;75(3):495-503. Epub 2015 Jan 4.

University of California San Diego, 9500 Gilman Drive, MC 0657, La Jolla, CA, 92093-0657, USA.

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http://dx.doi.org/10.1007/s00280-014-2667-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344382PMC
March 2015

Pediatric tectal plate gliomas: a review of clinical outcomes, endocrinopathies, and neuropsychological sequelae.

J Neurooncol 2015 Mar 13;122(1):169-77. Epub 2015 Jan 13.

Cancer and Blood Diseases Institute, Division of Oncology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA,

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March 2015

A phase 1 and pharmacokinetic study of enzastaurin in pediatric patients with refractory primary central nervous system tumors: a pediatric brain tumor consortium study.

Neuro Oncol 2015 Feb 27;17(2):303-11. Epub 2014 Nov 27.

Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas (L.B.K., M.C., J.S., S.M.B.); Department of Biostatistics, Operations and Biostatistics Center for Pediatric Brain Tumor Consortium, St. Jude Children's Research Hospital, Memphis, Tennessee (M.K., J.M.B.); Eli Lilly and Company, Indianapolis, Indiana (R.L.D.); Division of Neuro-oncology, St. Jude Children's Research Hospital, Memphis, Tennessee (C.W., R.G.); Ann and Robert H. Lurie Children's Hospital of Chicago, Center for Cancer and Blood Disorders, Northwestern University Feinberg School of Medicine, Chicago, Illinois (S.G.); Department of Pediatrics, Division of Hematology/Oncology, University of California San Francisco, San Francisco, California (A.B.); Department of Hematology Oncology, Cincinnati Children's Hospital Medical Center,Cincinnati, Ohio (M.F.); Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee (L.K.); Department of Preventive Medicine, University of Tennessee Health Science Center Memphis, Tennessee (M.K.).

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http://dx.doi.org/10.1093/neuonc/nou114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288513PMC
February 2015

Patterns of progression in pediatric patients with high-grade glioma or diffuse intrinsic pontine glioma treated with Bevacizumab-based therapy at diagnosis.

J Neurooncol 2015 Feb 30;121(3):591-8. Epub 2014 Nov 30.

Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA,

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February 2015

A phase I trial of veliparib (ABT-888) and temozolomide in children with recurrent CNS tumors: a pediatric brain tumor consortium report.

Neuro Oncol 2014 Dec 7;16(12):1661-8. Epub 2014 Jun 7.

Texas Children's Cancer Center, Baylor College of Medicine (J.M.S., P.T., A.A., X-N.L., S.M.B.); Children's National Medical Center (L.K.); St. Jude Children's Research Hospital (A.O-T., J.B., L.K.); University of Tennessee Health Science Center (M.K.); AbbVie Pharmaceuticals (B.C., E.M., V.G.); National Cancer Institute, Pediatric Oncology Branch (K.E.W.); Children's Hospital of Chicago (S.G.); Children's Hospital of Pittsburgh (I.F.P.); Cincinnati Children's Hospital Medical Center (M.F.); Cancer Therapy Evaluation Program, National Cancer Institute (A.C.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232081PMC
December 2014

18F-FDG PET and MR imaging associations across a spectrum of pediatric brain tumors: a report from the pediatric brain tumor consortium.

J Nucl Med 2014 Sep 28;55(9):1473-80. Epub 2014 Jul 28.

Department of Radiology, Harvard Medical School, Boston, Massachusetts Department of Radiology, Boston Children's Hospital, Boston, Massachusetts

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4249729PMC
September 2014

Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas.

J Neurooncol 2014 Mar 30;117(1):67-76. Epub 2014 Jan 30.

Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, MLC 7013, 3333 Burnet Ave, Cincinnati, OH, 45229, USA.

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http://dx.doi.org/10.1007/s11060-014-1374-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4261223PMC
March 2014

Cytogenetic prognostication within medulloblastoma subgroups.

J Clin Oncol 2014 Mar 3;32(9):886-96. Epub 2014 Feb 3.

David J.H. Shih, Marc Remke, Vijay Ramaswamy, Betty Luu, Yuan Yao, Xin Wang, Adrian M. Dubuc, Livia Garzia, John Peacock, Stephen C. Mack, Xiaochong Wu, Adi Rolider, A. Sorana Morrissy, Florence M.G. Cavalli, Claudia C. Faria, Stephen W. Scherer, Uri Tabori, Cynthia E. Hawkins, David Malkin, Eric Bouffet, James T. Rutka, and Michael D. Taylor, Hospital for Sick Children; David J.H. Shih, Marc Remke, Vijay Ramaswamy, Yuan Yao, Xin Wang, Adrian M. Dubuc, John Peacock, Stephen C. Mack, and Michael D. Taylor, University of Toronto, Toronto; Boleslaw Lach, McMaster University, Hamilton, Ontario; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Steffen Albrecht, Adam Fontebasso, and Nada Jabado, McGill University, Montreal, Quebec, Canada; Paul A. Northcott, Andrey Korshunov, Marcel Kool, David T.W. Jones, and Stefan M. Pfister, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Ulrich Schüller, Ludwig-Maximilians-University, Munich; Stefan Rutkowski, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Karel Zitterbart, Masaryk University School of Medicine; Karel Zitterbart and Leos Kren, University Hospital Brno, Brno, Czech Republic; Toshihiro Kumabe and Teiji Tominaga, Tohoku University Graduate School of Medicine, Sendai, Japan; Young Shin Ra, University of Ulsan, Asan Medical Center; Ji-Yeoun Lee, Byung-Kyu Cho, Seung-Ki Kim, and Kyu-Chang Wang, Seoul National University Children's Hospital, Seoul; Shin Jung, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Chonnam, South Korea; Peter Hauser and Miklós Garami, Semmelweis University, Budapest; László Bognár and Almos Klekner, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary; Shenandoah Robinson, Boston Children's Hospital; Scott L. Pomeroy, Harvard Medical School, Boston, MA; Ali G. Saad, University of Arkansas for Medical Sciences, Little

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948094PMC
March 2014

A phase I trial of imetelstat in children with refractory or recurrent solid tumors: a Children's Oncology Group Phase I Consortium Study (ADVL1112).

Clin Cancer Res 2013 Dec 4;19(23):6578-84. Epub 2013 Oct 4.

Authors' Affiliations: Texas Children's Cancer Center and Department of Pediatrics; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas; Division of Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Children's Oncology Group, Arcadia; Geron Corporation, Menlo Park, California; Department of Oncology, Mayo Clinic, Rochester; and Department of Pediatrics, Hematology-Oncology, University of Minnesota, Minneapolis, Minnesota.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079262PMC
December 2013

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma.

Acta Neuropathol 2013 Dec 31;126(6):917-29. Epub 2013 Oct 31.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00401-013-1198-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830749PMC
December 2013

Pharmacotherapeutic management of pediatric gliomas : current and upcoming strategies.

Paediatr Drugs 2013 Feb;15(1):29-42

Division of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1007/s40272-012-0002-4DOI Listing
February 2013

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

Cancer Cell 2012 Oct;22(4):425-37

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.

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October 2012

Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Authors:
Paul A Northcott David J H Shih John Peacock Livia Garzia A Sorana Morrissy Thomas Zichner Adrian M Stütz Andrey Korshunov Jüri Reimand Steven E Schumacher Rameen Beroukhim David W Ellison Christian R Marshall Anath C Lionel Stephen Mack Adrian Dubuc Yuan Yao Vijay Ramaswamy Betty Luu Adi Rolider Florence M G Cavalli Xin Wang Marc Remke Xiaochong Wu Readman Y B Chiu Andy Chu Eric Chuah Richard D Corbett Gemma R Hoad Shaun D Jackman Yisu Li Allan Lo Karen L Mungall Ka Ming Nip Jenny Q Qian Anthony G J Raymond Nina T Thiessen Richard J Varhol Inanc Birol Richard A Moore Andrew J Mungall Robert Holt Daisuke Kawauchi Martine F Roussel Marcel Kool David T W Jones Hendrick Witt Africa Fernandez-L Anna M Kenney Robert J Wechsler-Reya Peter Dirks Tzvi Aviv Wieslawa A Grajkowska Marta Perek-Polnik Christine C Haberler Olivier Delattre Stéphanie S Reynaud François F Doz Sarah S Pernet-Fattet Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Wolfram Scheurlen Charles G Eberhart Michelle Fèvre-Montange Anne Jouvet Ian F Pollack Xing Fan Karin M Muraszko G Yancey Gillespie Concezio Di Rocco Luca Massimi Erna M C Michiels Nanne K Kloosterhof Pim J French Johan M Kros James M Olson Richard G Ellenbogen Karel Zitterbart Leos Kren Reid C Thompson Michael K Cooper Boleslaw Lach Roger E McLendon Darell D Bigner Adam Fontebasso Steffen Albrecht Nada Jabado Janet C Lindsey Simon Bailey Nalin Gupta William A Weiss László Bognár Almos Klekner Timothy E Van Meter Toshihiro Kumabe Teiji Tominaga Samer K Elbabaa Jeffrey R Leonard Joshua B Rubin Linda M Liau Erwin G Van Meir Maryam Fouladi Hideo Nakamura Giuseppe Cinalli Miklós Garami Peter Hauser Ali G Saad Achille Iolascon Shin Jung Carlos G Carlotti Rajeev Vibhakar Young Shin Ra Shenandoah Robinson Massimo Zollo Claudia C Faria Jennifer A Chan Michael L Levy Poul H B Sorensen Matthew Meyerson Scott L Pomeroy Yoon-Jae Cho Gary D Bader Uri Tabori Cynthia E Hawkins Eric Bouffet Stephen W Scherer James T Rutka David Malkin Steven C Clifford Steven J M Jones Jan O Korbel Stefan M Pfister Marco A Marra Michael D Taylor

Nature 2012 Aug;488(7409):49-56

Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683624PMC
August 2012

Medulloblastoma with melanotic differentiation: case report and review of the literature.

J Neurooncol 2011 Jul 16;103(3):759-64. Epub 2010 Oct 16.

Division of Hematology/Oncology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA.

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July 2011

Determination of the gamma-secretase inhibitor MK-0752 in human plasma by online extraction and electrospray tandem mass spectrometry (HTLC-ESI-MS/MS).

J Chromatogr B Analyt Technol Biomed Life Sci 2010 Sep 30;878(25):2348-52. Epub 2010 Jul 30.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.jchromb.2010.07.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2926936PMC
September 2010

Clinical pharmacokinetics of amifostine and WR1065 in pediatric patients with medulloblastoma.

Clin Cancer Res 2010 Feb 26;16(3):1049-57. Epub 2010 Jan 26.

Department of Clinical Pharmacy and Pharmaceutical Sciences, University of Tennessee, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818675PMC
February 2010

Diffusion tensor imaging of brainstem tumors: axonal degeneration of motor and sensory tracts.

J Neurosurg Pediatr 2008 Apr;1(4):270-6

Department of Radiological Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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April 2008