Mary E Comeau

Mary E Comeau

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Mary E Comeau

Mary E Comeau

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Genetic Regulation of Enoyl-CoA Hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans.

Diabetes 2019 Jul 22;68(7):1508-1522. Epub 2019 Apr 22.

Section of Endocrinology and Metabolism, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC

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http://dx.doi.org/10.2337/db18-1229DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609988PMC
July 2019

Venous Thromboembolism in Patients With Spontaneous Intracerebral Hemorrhage: A Multicenter Study.

Neurosurgery 2019 Jun;84(6):E304-E310

Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, Ohio.

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http://dx.doi.org/10.1093/neuros/nyy333DOI Listing
June 2019

Adipose Tissue Transferrin and Insulin Resistance.

J Clin Endocrinol Metab 2018 Nov;103(11):4197-4208

Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.

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https://academic.oup.com/jcem/advance-article/doi/10.1210/jc
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http://dx.doi.org/10.1210/jc.2018-00770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6194856PMC
November 2018

Genome-wide association studies suggest that APOL1-environment interactions more likely trigger kidney disease in African Americans with nondiabetic nephropathy than strong APOL1-second gene interactions.

Kidney Int 2018 09 7;94(3):599-607. Epub 2018 Jun 7.

Center for Public Health Genomics; Wake Forest School of Medicine, Winston-Salem, North Carolina, USA; Center for Diabetes Research; Wake Forest School of Medicine, Winston-Salem, North Carolina, USA; Department of Internal Medicine, Section on Nephrology; Wake Forest School of Medicine, Winston-Salem, North Carolina, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2018.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6109415PMC
September 2018

A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.

Hum Mol Genet 2018 Jul;27(13):2392-2404

Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1093/hmg/ddy140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005081PMC
July 2018

Effects of weight-based ultrafiltration rate limits on intradialytic hypotension in hemodialysis.

Hemodial Int 2018 04 23;22(2):270-278. Epub 2017 Jun 23.

Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

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http://doi.wiley.com/10.1111/hdi.12578
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http://dx.doi.org/10.1111/hdi.12578DOI Listing
April 2018

Systemic inflammatory response syndrome, infection, and outcome in intracerebral hemorrhage.

Neurol Neuroimmunol Neuroinflamm 2018 Mar 22;5(2):e428. Epub 2017 Dec 22.

Department of Neurology (A.K.B., M.S.V.E.), College of Physicians and Surgeons, Columbia University; Department of Epidemiology (A.K.B., M.S.V.E.), Mailman School of Public Health, Columbia University, New York, NY; Wake Forest University (M.E.C., C.D.L.), NC; Department of Neurology (A.L.), New York University School of Medicine; Department of Neurology and Rehabilitation Medicine (C.J.M., J.O., D.W.), University of Cincinnati, OH; Departments of Anesthesiology and Neurology (M.L.J.), Duke University, Durham, NC; Baylor University, Houston, TX (S.M.); and University of Illinois Chicago (F.D.T.).

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http://dx.doi.org/10.1212/NXI.0000000000000428DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745360PMC
March 2018

Transcriptional Regulatory Mechanisms in Adipose and Muscle Tissue Associated with Composite Glucometabolic Phenotypes.

Obesity (Silver Spring) 2018 03 29;26(3):559-569. Epub 2018 Jan 29.

Department of Internal Medicine, School of Medicine, Wake Forest University, Winston-Salem, North Carolina, USA.

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http://dx.doi.org/10.1002/oby.22113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821540PMC
March 2018

Factors Considered by Clinicians when Prognosticating Intracerebral Hemorrhage Outcomes.

Neurocrit Care 2017 Dec;27(3):316-325

Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale School of Medicine, P.O. Box 208018, New Haven, CT, 06520, USA.

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http://dx.doi.org/10.1007/s12028-017-0430-7DOI Listing
December 2017

Genetic regulation of adipose tissue transcript expression is involved in modulating serum triglyceride and HDL-cholesterol.

Gene 2017 Oct 26;632:50-58. Epub 2017 Aug 26.

Department of Internal Medicine, Section on Endocrinology and Metabolism, Wake Forest School of Medicine, Winston-Salem, NC 27157, United States. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2017.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5600164PMC
October 2017

Use of Statins and Outcomes in Intracerebral Hemorrhage Patients.

Stroke 2017 08 29;48(8):2098-2104. Epub 2017 Jun 29.

From the Department of Neurology, Southern Illinois University School of Medicine, Springfield (F.M.S.); Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest University, Winston-Salem, NC (C.D.L., M.E.C.); Department of Neurology and Rehabilitation Medicine, University of Cincinnati, OH (C.J.M., P.S., J.L.O., D.W.); Center for Genomic Medicine, Massachusetts General Hospital, Boston (J.R.); Departments of Neurology and Medical Imaging, University of Arizona, Tucson (C.S.K.); Michael E. DeBakey VA Medical Center and Department of Neurology, Baylor College of Medicine, Houston, TX (S.M.); and Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas (S.S., C.H.).

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http://dx.doi.org/10.1161/STROKEAHA.117.017358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659292PMC
August 2017

Transancestral mapping and genetic load in systemic lupus erythematosus.

Authors:
Carl D Langefeld Hannah C Ainsworth Deborah S Cunninghame Graham Jennifer A Kelly Mary E Comeau Miranda C Marion Timothy D Howard Paula S Ramos Jennifer A Croker David L Morris Johanna K Sandling Jonas Carlsson Almlöf Eduardo M Acevedo-Vásquez Graciela S Alarcón Alejandra M Babini Vicente Baca Anders A Bengtsson Guillermo A Berbotto Marc Bijl Elizabeth E Brown Hermine I Brunner Mario H Cardiel Luis Catoggio Ricard Cervera Jorge M Cucho-Venegas Solbritt Rantapää Dahlqvist Sandra D'Alfonso Berta Martins Da Silva Iñigo de la Rúa Figueroa Andrea Doria Jeffrey C Edberg Emőke Endreffy Jorge A Esquivel-Valerio Paul R Fortin Barry I Freedman Johan Frostegård Mercedes A García Ignacio García de la Torre Gary S Gilkeson Dafna D Gladman Iva Gunnarsson Joel M Guthridge Jennifer L Huggins Judith A James Cees G M Kallenberg Diane L Kamen David R Karp Kenneth M Kaufman Leah C Kottyan László Kovács Helle Laustrup Bernard R Lauwerys Quan-Zhen Li Marco A Maradiaga-Ceceña Javier Martín Joseph M McCune David R McWilliams Joan T Merrill Pedro Miranda José F Moctezuma Swapan K Nath Timothy B Niewold Lorena Orozco Norberto Ortego-Centeno Michelle Petri Christian A Pineau Bernardo A Pons-Estel Janet Pope Prithvi Raj Rosalind Ramsey-Goldman John D Reveille Laurie P Russell José M Sabio Carlos A Aguilar-Salinas Hugo R Scherbarth Raffaella Scorza Michael F Seldin Christopher Sjöwall Elisabet Svenungsson Susan D Thompson Sergio M A Toloza Lennart Truedsson Teresa Tusié-Luna Carlos Vasconcelos Luis M Vilá Daniel J Wallace Michael H Weisman Joan E Wither Tushar Bhangale Jorge R Oksenberg John D Rioux Peter K Gregersen Ann-Christine Syvänen Lars Rönnblom Lindsey A Criswell Chaim O Jacob Kathy L Sivils Betty P Tsao Laura E Schanberg Timothy W Behrens Earl D Silverman Marta E Alarcón-Riquelme Robert P Kimberly John B Harley Edward K Wakeland Robert R Graham Patrick M Gaffney Timothy J Vyse

Nat Commun 2017 07 17;8:16021. Epub 2017 Jul 17.

Divisions of Genetics and Molecular Medicine and Immunology, Infection and Inflammatory Diseases, King's College London, Guy's Hospital, London SE1 9RT, UK.

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http://dx.doi.org/10.1038/ncomms16021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520018PMC
July 2017

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.

Authors:
Philip C Haycock Stephen Burgess Aayah Nounu Jie Zheng George N Okoli Jack Bowden Kaitlin Hazel Wade Nicholas J Timpson David M Evans Peter Willeit Abraham Aviv Tom R Gaunt Gibran Hemani Massimo Mangino Hayley Patricia Ellis Kathreena M Kurian Karen A Pooley Rosalind A Eeles Jeffrey E Lee Shenying Fang Wei V Chen Matthew H Law Lisa M Bowdler Mark M Iles Qiong Yang Bradford B Worrall Hugh Stephen Markus Rayjean J Hung Chris I Amos Amanda B Spurdle Deborah J Thompson Tracy A O'Mara Brian Wolpin Laufey Amundadottir Rachael Stolzenberg-Solomon Antonia Trichopoulou N Charlotte Onland-Moret Eiliv Lund Eric J Duell Federico Canzian Gianluca Severi Kim Overvad Marc J Gunter Rosario Tumino Ulrika Svenson Andre van Rij Annette F Baas Matthew J Bown Nilesh J Samani Femke N G van t'Hof Gerard Tromp Gregory T Jones Helena Kuivaniemi James R Elmore Mattias Johansson James Mckay Ghislaine Scelo Robert Carreras-Torres Valerie Gaborieau Paul Brennan Paige M Bracci Rachel E Neale Sara H Olson Steven Gallinger Donghui Li Gloria M Petersen Harvey A Risch Alison P Klein Jiali Han Christian C Abnet Neal D Freedman Philip R Taylor John M Maris Katja K Aben Lambertus A Kiemeney Sita H Vermeulen John K Wiencke Kyle M Walsh Margaret Wrensch Terri Rice Clare Turnbull Kevin Litchfield Lavinia Paternoster Marie Standl Gonçalo R Abecasis John Paul SanGiovanni Yong Li Vladan Mijatovic Yadav Sapkota Siew-Kee Low Krina T Zondervan Grant W Montgomery Dale R Nyholt David A van Heel Karen Hunt Dan E Arking Foram N Ashar Nona Sotoodehnia Daniel Woo Jonathan Rosand Mary E Comeau W Mark Brown Edwin K Silverman John E Hokanson Michael H Cho Jennie Hui Manuel A Ferreira Philip J Thompson Alanna C Morrison Janine F Felix Nicholas L Smith Angela M Christiano Lynn Petukhova Regina C Betz Xing Fan Xuejun Zhang Caihong Zhu Carl D Langefeld Susan D Thompson Feijie Wang Xu Lin David A Schwartz Tasha Fingerlin Jerome I Rotter Mary Frances Cotch Richard A Jensen Matthias Munz Henrik Dommisch Arne S Schaefer Fang Han Hanna M Ollila Ryan P Hillary Omar Albagha Stuart H Ralston Chenjie Zeng Wei Zheng Xiao-Ou Shu Andre Reis Steffen Uebe Ulrike Hüffmeier Yoshiya Kawamura Takeshi Otowa Tsukasa Sasaki Martin Lloyd Hibberd Sonia Davila Gang Xie Katherine Siminovitch Jin-Xin Bei Yi-Xin Zeng Asta Försti Bowang Chen Stefano Landi Andre Franke Annegret Fischer David Ellinghaus Carlos Flores Imre Noth Shwu-Fan Ma Jia Nee Foo Jianjun Liu Jong-Won Kim David G Cox Olivier Delattre Olivier Mirabeau Christine F Skibola Clara S Tang Merce Garcia-Barcelo Kai-Ping Chang Wen-Hui Su Yu-Sun Chang Nicholas G Martin Scott Gordon Tracey D Wade Chaeyoung Lee Michiaki Kubo Pei-Chieng Cha Yusuke Nakamura Daniel Levy Masayuki Kimura Shih-Jen Hwang Steven Hunt Tim Spector Nicole Soranzo Ani W Manichaikul R Graham Barr Bratati Kahali Elizabeth Speliotes Laura M Yerges-Armstrong Ching-Yu Cheng Jost B Jonas Tien Yin Wong Isabella Fogh Kuang Lin John F Powell Kenneth Rice Caroline L Relton Richard M Martin George Davey Smith

JAMA Oncol 2017 May;3(5):636-651

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, England2School of Social and Community Medicine, University of Bristol, Bristol, England.

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http://dx.doi.org/10.1001/jamaoncol.2016.5945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638008PMC
May 2017

APOL1 renal-risk genotypes associate with longer hemodialysis survival in prevalent nondiabetic African American patients with end-stage renal disease.

Kidney Int 2016 08 6;90(2):389-395. Epub 2016 May 6.

Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA; Center for Public Health Genomics, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA; Center for Genomics and Personalized Medicine Research, Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2016.02.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946964PMC
August 2016

Relationships between measures of adiposity with subclinical atherosclerosis in patients with type 2 diabetes.

Obesity (Silver Spring) 2016 08 29;24(8):1810-8. Epub 2016 Jun 29.

Department of Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.

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http://dx.doi.org/10.1002/oby.21540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963287PMC
August 2016

Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans.

J Clin Endocrinol Metab 2016 Apr 20;101(4):1455-68. Epub 2016 Jan 20.

Department of Internal Medicine (N.K.S., J.C.-E., J.D., S.R., L.Ma., K.C., L.Me., E.K., D.D., B.I.F., S.K.D.), Center for Public Health Genomics (N.K.S., S.P.S., J.W.C., L.Ma., N.D.P., D.R.M., M.C., G.A.H., B.I.F., C.D.L., S.K.D.), Department of Biostatistical Sciences, Division of Public Health Sciences (S.P.S., J.W.C., D.R.M., J.B., M.C., C.D.L.), Department of Biochemistry (N.D.P., D.W.B.), Center for Diabetes Research and Center for Genomics and Personalized Medicine Research (N.D.P., G.A.H., D.W.B., B.I.F.), and Clinical Research Unit, Biomedical Research Services and Administration (M.B., S.J.B., L.E.), Wake Forest School of Medicine, Winston-Salem, North Carolina 27157.

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http://dx.doi.org/10.1210/jc.2015-3336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880154PMC
April 2016

Clinician judgment vs formal scales for predicting intracerebral hemorrhage outcomes.

Neurology 2016 Jan 16;86(2):126-33. Epub 2015 Dec 16.

From the Division of Neurocritical Care and Emergency Neurology (D.Y.H., K.N.S.), Department of Neurology, Yale School of Medicine, New Haven, CT; the Maryland Stroke Center (C.A.D., M.J.S., T.D.W.), Baltimore; the Center for Public Health Genomics and Department of Biostatistical Sciences (C.D.L., M.E.C.), Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC; the Center for Human Genetic Research (J.R., T.W.K.B.), Boston, MA; the University of Miami (S.K., M.L.P.), Miller School of Medicine, FL; Duke University Medical Center (M.L.J., J.M.), Durham, NC; the Department of Neurology (J.L.O., D.W.), University of Cincinnati College of Medicine, OH; and the Baltimore Veterans Administration Medical Center and University of Maryland School of Medicine (S.J.K.).

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http://www.neurology.org/content/86/2/126.full.pdf
Web Search
http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000002266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731687PMC
January 2016

Prophylactic Antiepileptic Drug Use and Outcome in the Ethnic/Racial Variations of Intracerebral Hemorrhage Study.

Stroke 2015 Dec 15;46(12):3532-5. Epub 2015 Oct 15.

From the Department of Neurology, Yale University School of Medicine, New Haven, CT (K.N.S.); Department of Neurology, Baylor College of Medicine, Houston, TX (S.R.M.); Department of Neurology and Rehabilitation Medicine, University of Cincinnati, OH (C.J.M., J.O., D.W.); Department of Neurology, University of Miami School of Medicine, Miami, FL (S.K.); Department of Neurology, College of Physicians and Surgeons, Columbia University, New York (M.S.V.E.); Department of Neurology, University of Southern California, Los Angeles (G.S.); Department of Neurology, University of Maryland School of Medicine, Baltimore, MD (S.J.K.); Department of Neurology, Emory University School of Medicine, Atlanta, GA (M.F.); Department of Neurology, Massachusetts General Hospital, Boston, MA (J.R.); Department of Biostatistical Sciences and Center for Public Health Genomics, Wake Forest School of Medicine, Winston-Salem, NC (C.D.L., M.E.C.); and Office of Clinical Research, National Institute of Neurological Disorders and Stroke, Bethesda, MD (S.P.W.).

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http://dx.doi.org/10.1161/STROKEAHA.115.010875DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659755PMC
December 2015

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.

PLoS Genet 2014 Aug 7;10(8):e1004517. Epub 2014 Aug 7.

Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125087PMC
August 2014

Meta-analysis of genome-wide association studies identifies 1q22 as a susceptibility locus for intracerebral hemorrhage.

Am J Hum Genet 2014 Apr 20;94(4):511-21. Epub 2014 Mar 20.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA; Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Massachusetts General Hospital, Boston, MA 02114, USA; The J. Philip Kistler Stroke Research Center, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02141, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.02.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980413PMC
April 2014

Polymorphisms in MYH9 are associated with diabetic nephropathy in European Americans.

Nephrol Dial Transplant 2012 Apr 3;27(4):1505-11. Epub 2011 Oct 3.

Program in Molecular Medicine and Translational Science, Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1093/ndt/gfr522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3315672PMC
April 2012

Is collapsing C1q nephropathy another MYH9-associated kidney disease? A case report.

Am J Kidney Dis 2010 May 29;55(5):e21-4. Epub 2010 Jan 29.

Department of Internal Medicine-Nephrology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S02726386090159
Publisher Site
http://dx.doi.org/10.1053/j.ajkd.2009.10.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864358PMC
May 2010

Non-muscle myosin heavy chain 9 gene MYH9 associations in African Americans with clinically diagnosed type 2 diabetes mellitus-associated ESRD.

Nephrol Dial Transplant 2009 Nov 30;24(11):3366-71. Epub 2009 Jun 30.

1Internal Medicine/Nephrology, 2Biochemistry, 3Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

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http://dx.doi.org/10.1093/ndt/gfp316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910323PMC
November 2009