Mary Armanios

Mary Armanios

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Mary Armanios

Mary Armanios

Publications by authors named "Mary Armanios"

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Equity and diversity in academic medicine: a perspective from the JCI editors.

J Clin Invest 2019 Oct;129(10):3974-3977

Department of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1172/JCI130902DOI Listing
October 2019

Short lymphocyte, but not granulocyte, telomere length in a subset of patients with systemic sclerosis.

Ann Rheum Dis 2019 Aug 24;78(8):1142-1144. Epub 2019 Jan 24.

Division of Rheumatology, Northwestern Scleroderma Program, Feinberg School of Medicine, Northwestern University, Chicago, Illinois‎, USA

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http://dx.doi.org/10.1136/annrheumdis-2018-214499DOI Listing
August 2019

Long telomeres and cancer risk: the price of cellular immortality.

J Clin Invest 2019 08 5;130:3474-3481. Epub 2019 Aug 5.

Department of Oncology.

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http://dx.doi.org/10.1172/JCI120851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715353PMC
August 2019

Telomeres in the Clinic, Not on TV.

Authors:
Mary Armanios

Mayo Clin Proc 2018 07;93(7):815-817

Department of Oncology, McKusick-Nathans Institute of Genetic Medicine, Telomere Center, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2018.05.024DOI Listing
July 2018

Diagnostic utility of telomere length testing in a hospital-based setting.

Proc Natl Acad Sci U S A 2018 03 20;115(10):E2358-E2365. Epub 2018 Feb 20.

Department of Oncology and Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD 21287;

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http://dx.doi.org/10.1073/pnas.1720427115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877993PMC
March 2018

IPF lung fibroblasts have a senescent phenotype.

Am J Physiol Lung Cell Mol Physiol 2017 Dec 31;313(6):L1164-L1173. Epub 2017 Aug 31.

The Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, Pittsburgh, Pennsylvania;

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http://dx.doi.org/10.1152/ajplung.00220.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6148001PMC
December 2017

Germline Mutations in DNA Repair Genes in Lung Adenocarcinoma.

J Thorac Oncol 2017 11 24;12(11):1673-1678. Epub 2017 Aug 24.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2017.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659909PMC
November 2017

Shall we call them "telomere-mediated"? Renaming the idiopathic after the cause is found.

Eur Respir J 2016 12;48(6):1556-1558

Dept of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

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http://dx.doi.org/10.1183/13993003.02115-2016DOI Listing
December 2016

Robust reprogramming of Ataxia-Telangiectasia patient and carrier erythroid cells to induced pluripotent stem cells.

Stem Cell Res 2016 09 12;17(2):296-305. Epub 2016 Aug 12.

Department of Radiation Oncology and Molecular Radiation Sciences, and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2016.08.006DOI Listing
September 2016

Integration-free erythroblast-derived human induced pluripotent stem cells (iPSCs) from an individual with Ataxia-Telangiectasia (A-T).

Stem Cell Res 2016 09 5;17(2):205-207. Epub 2016 Aug 5.

Department of Radiation Oncology and Molecular Radiation Sciences, and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/j.scr.2016.08.003DOI Listing
September 2016

Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema.

Sci Transl Med 2016 08;8(351):351ra107

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaf7837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5351811PMC
August 2016

Case 41-2015: A Boy with Immune and Liver Abnormalities.

N Engl J Med 2016 06;374(22):2193

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http://dx.doi.org/10.1056/NEJMc1601156DOI Listing
June 2016

A Syndromic Intellectual Disability Disorder Caused by Variants in TELO2, a Gene Encoding a Component of the TTT Complex.

Am J Hum Genet 2016 05 28;98(5):909-918. Epub 2016 Apr 28.

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Greenberg Center for Skeletal Dysplasias, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1016/j.ajhg.2016.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4863664PMC
May 2016

Radiation Sensitivity and Radiation Necrosis in the Short Telomere Syndromes.

Int J Radiat Oncol Biol Phys 2015 Dec 4;93(5):1115-7. Epub 2015 Sep 4.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2015.08.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4708077PMC
December 2015

Translational strategies in aging and age-related disease.

Nat Med 2015 Dec;21(12):1395-9

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1038/nm.4004DOI Listing
December 2015

Hepatopulmonary syndrome is a frequent cause of dyspnea in the short telomere disorders.

Chest 2015 Oct;148(4):1019-1026

Department of Oncology, Baltimore, MD; Department of Pathology, Baltimore, MD; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address:

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http://dx.doi.org/10.1378/chest.15-0825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594621PMC
October 2015

Treating Myeloproliferation--On Target or Off?

N Engl J Med 2015 Sep;373(10):965-6

From the Departments of Oncology (M.A.) and Molecular Biology and Genetics (C.W.G.) and the Sidney Kimmel Comprehensive Cancer Center (M.A., C.W.G.), Johns Hopkins University School of Medicine, Baltimore.

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http://dx.doi.org/10.1056/NEJMe1508740DOI Listing
September 2015

The short and long telomere syndromes: paired paradigms for molecular medicine.

Curr Opin Genet Dev 2015 Aug 29;33:1-9. Epub 2015 Jul 29.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; McKusick Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2015.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741306PMC
August 2015

Telomere dysfunction causes alveolar stem cell failure.

Proc Natl Acad Sci U S A 2015 Apr 3;112(16):5099-104. Epub 2015 Apr 3.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, and McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205;

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http://dx.doi.org/10.1073/pnas.1504780112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413294PMC
April 2015

What the genetics "RTEL"ing us about telomeres and pulmonary fibrosis.

Am J Respir Crit Care Med 2015 Mar;191(6):608-10

1 Medical Scientist Training Program and.

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http://dx.doi.org/10.1164/rccm.201501-0119EDDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384782PMC
March 2015

Lung transplantation in telomerase mutation carriers with pulmonary fibrosis.

Eur Respir J 2014 Jul 15;44(1):178-87. Epub 2014 May 15.

Dept of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA

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http://erj.ersjournals.com/content/erj/44/1/178.full.pdf
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http://erj.ersjournals.com/cgi/doi/10.1183/09031936.00060014
Publisher Site
http://dx.doi.org/10.1183/09031936.00060014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4076528PMC
July 2014

Short telomeres: a repeat offender in IPF.

Lancet Respir Med 2014 Jul 24;2(7):513-4. Epub 2014 Jun 24.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(14)70140-7DOI Listing
July 2014

Detection of paroxysmal nocturnal hemoglobinuria clones to exclude inherited bone marrow failure syndromes.

Eur J Haematol 2014 Jun 18;92(6):467-70. Epub 2014 Mar 18.

The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; Division of Hematology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1111/ejh.12299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161035PMC
June 2014

Reply: telomerase makes connections between pulmonary fibrosis and emphysema.

Authors:
Mary Armanios

Am J Respir Crit Care Med 2014 Mar;189(6):754-5

1 Johns Hopkins University School of Medicine Baltimore, Maryland.

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http://dx.doi.org/10.1164/rccm.201401-0019LEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983841PMC
March 2014

Telomere phenotypes in females with heterozygous mutations in the dyskeratosis congenita 1 (DKC1) gene.

Hum Mutat 2013 Nov 11;34(11):1481-5. Epub 2013 Sep 11.

Department of Oncology and Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/humu.22397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926107PMC
November 2013

The gastrointestinal manifestations of telomere-mediated disease.

Aging Cell 2013 Apr 4;12(2):319-23. Epub 2013 Jan 4.

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1111/acel.12041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602337PMC
April 2013

Telomeres and age-related disease: how telomere biology informs clinical paradigms.

Authors:
Mary Armanios

J Clin Invest 2013 Mar 1;123(3):996-1002. Epub 2013 Mar 1.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, and McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1172/JCI66370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3673231PMC
March 2013

The telomere syndromes.

Nat Rev Genet 2012 Oct 11;13(10):693-704. Epub 2012 Sep 11.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA.

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http://dx.doi.org/10.1038/nrg3246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548426PMC
October 2012

An emerging role for the conserved telomere component 1 (CTC1) in human genetic disease.

Authors:
Mary Armanios

Pediatr Blood Cancer 2012 Aug 3;59(2):209-10. Epub 2012 May 3.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/pbc.24200DOI Listing
August 2012

Telomerase mutations and the pulmonary fibrosis-bone marrow failure syndrome complex.

Authors:
Mary Armanios

N Engl J Med 2012 07;367(4):384; author reply 384

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http://dx.doi.org/10.1056/NEJMc1206730DOI Listing
July 2012

Telomerase and idiopathic pulmonary fibrosis.

Authors:
Mary Armanios

Mutat Res 2012 Feb 4;730(1-2):52-8. Epub 2011 Nov 4.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002751071100289
Publisher Site
http://dx.doi.org/10.1016/j.mrfmmm.2011.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292861PMC
February 2012

Telomeres and disease: an overview.

Mutat Res 2012 Feb 11;730(1-2):1-2. Epub 2011 Nov 11.

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http://dx.doi.org/10.1016/j.mrfmmm.2011.11.005DOI Listing
February 2012

Telomere length is a determinant of emphysema susceptibility.

Am J Respir Crit Care Med 2011 Oct 14;184(8):904-12. Epub 2011 Jul 14.

Department of Oncology, Johns Hopkins University School of Medicine, 1650 Orleans Street, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1164/rccm.201103-0520OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208661PMC
October 2011

Decreased dyskerin levels as a mechanism of telomere shortening in X-linked dyskeratosis congenita.

J Med Genet 2011 May 17;48(5):327-33. Epub 2011 Mar 17.

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, 1650 Orleans St., CRB 186, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1136/jmg.2010.085100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3088476PMC
May 2011

Syndrome complex of bone marrow failure and pulmonary fibrosis predicts germline defects in telomerase.

Blood 2011 May 24;117(21):5607-11. Epub 2011 Mar 24.

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1182/blood-2010-11-322149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110022PMC
May 2011

Short telomeres compromise β-cell signaling and survival.

PLoS One 2011 Mar 10;6(3):e17858. Epub 2011 Mar 10.

Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017858PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053388PMC
March 2011

Syndromes of telomere shortening.

Authors:
Mary Armanios

Annu Rev Genomics Hum Genet 2009 ;10:45-61

Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21285, USA.

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http://dx.doi.org/10.1146/annurev-genom-082908-150046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818564PMC
October 2009

Dyskeratosis congenita: the first NIH clinical research workshop.

Pediatr Blood Cancer 2009 Sep;53(3):520-3

Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA.

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http://dx.doi.org/10.1002/pbc.22061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2739803PMC
September 2009

Short telomeres are a risk factor for idiopathic pulmonary fibrosis.

Proc Natl Acad Sci U S A 2008 Sep 27;105(35):13051-6. Epub 2008 Aug 27.

Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA.

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http://dx.doi.org/10.1073/pnas.0804280105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2529100PMC
September 2008

Short telomeres, even in the presence of telomerase, limit tissue renewal capacity.

Cell 2005 Dec;123(6):1121-31

Department of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/j.cell.2005.11.020DOI Listing
December 2005

Short telomeres and ataxia-telangiectasia mutated deficiency cooperatively increase telomere dysfunction and suppress tumorigenesis.

Cancer Res 2003 Dec;63(23):8188-96

Departments of Molecular Biology and Genetics, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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December 2003