Marwan Fakih

Marwan Fakih

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Marwan Fakih

Publications by authors named "Marwan Fakih"

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PD-1 Blockade in a Liver Transplant Recipient With Microsatellite Unstable Metastatic Colorectal Cancer and Hepatic Impairment.

J Natl Compr Canc Netw 2019 Sep;17(9):1026-1030

aDepartment of Hematology and Oncology, University of California, Davis, Sacramento.

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http://dx.doi.org/10.6004/jnccn.2019.7328DOI Listing
September 2019

Efficacy of PD-1 Blockade in Refractory Microsatellite-Stable Colorectal Cancer With High Tumor Mutation Burden.

Clin Colorectal Cancer 2019 Sep 4. Epub 2019 Sep 4.

Division of Hematology and Oncology, Department of Internal Medicine, UC Davis Comprehensive Cancer Center, Sacramento, CA. Electronic address:

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http://dx.doi.org/10.1016/j.clcc.2019.08.001DOI Listing
September 2019

A Pilot Study of Vinorelbine Safety and Pharmacokinetics in Patients with Varying Degrees of Liver Dysfunction.

Oncologist 2019 Aug 1;24(8):1137-1145. Epub 2019 Feb 1.

Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, California, USA

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http://dx.doi.org/10.1634/theoncologist.2018-0336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693729PMC
August 2019

Systemic treatment for metastatic colorectal cancer in the era of precision medicine.

J Surg Oncol 2019 Apr 25;119(5):564-582. Epub 2019 Feb 25.

Medical Oncology and Therapeutics Research, Briskin Center for Clinical Research, GI Medical Oncology, City of Hope Comprehensive Cancer Center, Duarte, California.

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http://doi.wiley.com/10.1002/jso.25421
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http://dx.doi.org/10.1002/jso.25421DOI Listing
April 2019

Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme.

Cell Chem Biol 2019 Feb 20;26(2):278-288.e6. Epub 2018 Dec 20.

Department of Molecular Medicine, The Beckman Research Institute, City of Hope National Medical Center, Duarte, CA, USA; Irell and Manella Graduate School of Biological Sciences of City of Hope, Duarte, CA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24519456183038
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http://dx.doi.org/10.1016/j.chembiol.2018.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524651PMC
February 2019

Complete response to pembrolizumab in a patient with metastatic colon cancer with microsatellite instability and a history of Guillain-Barre syndrome.

J Gastrointest Oncol 2019 Feb;10(1):161-165

Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA.

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http://dx.doi.org/10.21037/jgo.2018.09.19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351297PMC
February 2019

Trastuzumab Plus Pertuzumab Resistance Does Not Preclude Response to Lapatinib Plus Trastuzumab in HER2-Amplified Colorectal Cancer.

Authors:
Marwan G Fakih

Oncologist 2018 04 12;23(4):474-477. Epub 2018 Jan 12.

Gastrointestinal Cancer Section, City of Hope National Medical Center, Duarte, California, USA

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http://dx.doi.org/10.1634/theoncologist.2017-0436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896709PMC
April 2018

Value-based genomics.

Oncotarget 2018 Mar 30;9(21):15792-15815. Epub 2018 Jan 30.

Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.

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http://dx.doi.org/10.18632/oncotarget.24353DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884665PMC
March 2018

Empowering survivors after colorectal and lung cancer treatment: Pilot study of a Self-Management Survivorship Care Planning intervention.

Eur J Oncol Nurs 2017 Aug 19;29:125-134. Epub 2017 Jun 19.

Division of Nursing Research and Education, Department of Population Sciences, City of Hope Comprehensive Cancer Center, Duarte, CA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ejon.2017.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539921PMC
August 2017

The International Duration Evaluation of Adjuvant Chemotherapy study: implications for clinical practice.

Authors:
Marwan Fakih

J Gastrointest Oncol 2017 Aug;8(4):603-607

Department of Medical Oncology and Therapeutics Research, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.

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http://dx.doi.org/10.21037/jgo.2017.07.08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582034PMC
August 2017

Molecular profiling of metastatic colorectal tumors using next-generation sequencing: a single-institution experience.

Oncotarget 2017 Jun;8(26):42198-42213

Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA, USA.

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http://dx.doi.org/10.18632/oncotarget.15030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522060PMC
June 2017

MEK162 Enhances Antitumor Activity of 5-Fluorouracil and Trifluridine in KRAS-mutated Human Colorectal Cancer Cell Lines.

Anticancer Res 2017 06;37(6):2831-2838

Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, U.S.A.

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http://dx.doi.org/10.21873/anticanres.11634DOI Listing
June 2017

Chemotherapy in patients with hepatobiliary cancers and abnormal hepatic function.

J Gastrointest Oncol 2017 Apr;8(2):314-323

Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.

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http://dx.doi.org/10.21037/jgo.2016.09.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401853PMC
April 2017

Response to PD-1 Blockade in Microsatellite Stable Metastatic Colorectal Cancer Harboring a Mutation.

J Natl Compr Canc Netw 2017 02;15(2):142-147

Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, California

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http://dx.doi.org/10.6004/jnccn.2017.0016DOI Listing
February 2017

Reliability, Validity, and Feasibility of a Computer-Based Geriatric Assessment for Older Adults With Cancer.

J Oncol Pract 2016 12 30;12(12):e1025-e1034. Epub 2016 Sep 30.

City of Hope Comprehensive Cancer Center and Beckman Research Institute, Duarte, CA; Duke University Medical Center, Durham, NC; Breast Cancer Advocate, New York, NY; and Northwestern University Feinberg School of Medicine, Chicago, IL.

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http://dx.doi.org/10.1200/JOP.2016.013136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455588PMC
December 2016

Reliability, Validity, and Feasibility of a Computer-Based Geriatric Assessment for Older Adults With Cancer.

J Oncol Pract 2016 12 30;12(12):e1025-e1034. Epub 2016 Sep 30.

City of Hope Comprehensive Cancer Center and Beckman Research Institute, Duarte, CA; Duke University Medical Center, Durham, NC; Breast Cancer Advocate, New York, NY; and Northwestern University Feinberg School of Medicine, Chicago, IL.

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http://dx.doi.org/10.1200/JOP.2016.013136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455588PMC
December 2016

Effect of increasing radiation dose on pathologic complete response in rectal cancer patients treated with neoadjuvant chemoradiation therapy.

Acta Oncol 2016 Dec 20;55(12):1392-1399. Epub 2016 Oct 20.

a Department of Radiation Oncology , City of Hope National Medical Center , Duarte , CA , USA.

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http://dx.doi.org/10.1080/0284186X.2016.1235797DOI Listing
December 2016

Impressive response to dual and MEK inhibition in patients with BRAF mutant intrahepatic cholangiocarcinoma-2 case reports and a brief review.

J Gastrointest Oncol 2016 Dec;7(6):E98-E102

Department of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, USA.

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http://dx.doi.org/10.21037/jgo.2016.09.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177579PMC
December 2016

RAS and BRAF in metastatic colorectal cancer management.

J Gastrointest Oncol 2016 Oct;7(5):687-704

Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.

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http://dx.doi.org/10.21037/jgo.2016.06.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056249PMC
October 2016

The state of regional therapy in the management of metastatic colorectal cancer to the liver.

Expert Rev Anticancer Ther 2016 13;16(2):229-45. Epub 2016 Jan 13.

a Department of Medical Oncology , City of Hope National Medical Center , Duarte , CA , USA.

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http://dx.doi.org/10.1586/14737140.2016.1129277DOI Listing
September 2016

Pilot study of an interdisciplinary supportive care planning intervention in pancreatic cancer.

Support Care Cancer 2016 08 17;24(8):3417-24. Epub 2016 Mar 17.

Division of Nursing Research and Education, Department of Population Sciences, City of Hope, 1500 East Duarte Road, Duarte, CA, 91010, USA.

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http://dx.doi.org/10.1007/s00520-016-3155-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919144PMC
August 2016

Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal.

Nat Commun 2016 07 28;7:12326. Epub 2016 Jul 28.

Department of Molecular Medicine, Beckman Research Institute of City of Hope, Duarte, California 91010, USA.

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http://dx.doi.org/10.1038/ncomms12326DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974481PMC
July 2016

Biologic therapies in colorectal cancer: indications and contraindications.

Authors:
Marwan Fakih

Am Soc Clin Oncol Educ Book 2015 :e197-206

From the City of Hope Comprehensive Cancer Center, Duarte, CA.

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http://dx.doi.org/10.14694/EdBook_AM.2015.35.e197DOI Listing
February 2016

Epidermal Growth Factor Receptor Signaling to the Mitogen Activated Protein Kinase Pathway Bypasses Ras in Pancreatic Cancer Cells.

Pancreas 2016 Feb;45(2):286-92

From the *Division of Surgical Oncology, Departments of Surgery and †Medical Oncology and Experimental Therapeutics, City of Hope National Medical Center, Duarte, CA; and ‡Department of Surgery, Stony Brook Medicine, Stony Brook, NY.

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http://pdfs.journals.lww.com/pancreasjournal/2016/02000/Epid
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/MPA.0000000000000379DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5891223PMC
February 2016

Impact of RAS and BRAF mutations on carcinoembryonic antigen production and pattern of colorectal metastases.

World J Gastrointest Oncol 2016 Jan;8(1):128-35

May Cho, Chie Akiba, Cecilia Lau, Marwan Fakih, Department of Medical Oncology, City of Hope National Medical Center, Duarte, CA 91010, United States.

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http://dx.doi.org/10.4251/wjgo.v8.i1.128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714142PMC
January 2016

Impact of Total Lymph Node Count on Staging and Survival After Neoadjuvant Chemoradiation Therapy for Rectal Cancer.

Ann Surg Oncol 2015 Dec 9;22 Suppl 3:S580-7. Epub 2015 May 9.

Department of Radiation Oncology, City of Hope National Medical Cancer, Duarte, CA, USA.

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http://link.springer.com/10.1245/s10434-015-4585-1
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http://dx.doi.org/10.1245/s10434-015-4585-1DOI Listing
December 2015

A case of fibrolamellar cancer with a palliative response and minor radiographic regression with erlotinib and bevacizumab combination therapy.

Authors:
Marwan Fakih

Am J Ther 2014 Nov-Dec;21(6):e207-10

Department of Medical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, CA.

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http://dx.doi.org/10.1097/MJT.0b013e3182840fa6DOI Listing
July 2015

Accuracy of computed tomography in nodal staging of colon cancer patients.

World J Gastrointest Surg 2015 Jul;7(7):116-22

Audrey H Choi, Hans F Schoellhammer, Won Cho, Michelle Ko, Amanda Arrington, Christopher R Oxner, Stephen M Sentovich, Julio Garcia-Aguilar, Joseph Kim, Department of Surgery, City of Hope National Medical Center, Duarte, CA 91010, United States.

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http://dx.doi.org/10.4240/wjgs.v7.i7.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513434PMC
July 2015

Metastatic colorectal cancer: current state and future directions.

Authors:
Marwan G Fakih

J Clin Oncol 2015 Jun 27;33(16):1809-24. Epub 2015 Apr 27.

Marwan G. Fakih, Gastrointestinal Medical Oncology, City of Hope Comprehensive Cancer Center, Duarte, CA.

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http://dx.doi.org/10.1200/JCO.2014.59.7633DOI Listing
June 2015

The emerging role of neoadjuvant chemotherapy for rectal cancer.

J Gastrointest Oncol 2014 Oct;5(5):362-73

1 Roswell Park Cancer Institute, Buffalo, NY 14263, USA ; 2 City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.

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http://www.thejgo.org/article/view/3072/3543
Publisher Site
http://dx.doi.org/10.3978/j.issn.2078-6891.2014.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173043PMC
October 2014

TP53 and let-7a micro-RNA regulate K-Ras activity in HCT116 colorectal cancer cells.

PLoS One 2013 1;8(8):e70604. Epub 2013 Aug 1.

Division of Surgical Oncology, Department of Surgery, City of Hope Comprehensive Cancer Center, Duarte, California, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070604PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731270PMC
March 2014

Targeted therapies in colorectal cancer: the dos, don'ts, and future directions.

Authors:
Marwan Fakih

J Gastrointest Oncol 2013 Sep;4(3):239-44

City of Hope Comprehensive Cancer Center, 1500 E Duarte St, Duarte, CA 91010, USA.

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http://dx.doi.org/10.3978/j.issn.2078-6891.2013.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712299PMC
September 2013

Multigene assays in metastatic colorectal cancer.

J Natl Compr Canc Netw 2013 Sep;11 Suppl 4:S9-17

From the aCenter for Human Genetics Laboratory, Case Western Reserve University, Cleveland, Ohio; bClinical Molecular Diagnostic Laboratory, Department of Pathology, City of Hope Comprehensive Cancer Center, Duarte, California; cFulgent Therapeutics Inc, Temple City, California; and dMedical Oncology and Experimental Therapeutics, City of Hope Comprehensive Cancer Center, Duarte, California.

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http://dx.doi.org/10.6004/jnccn.2013.0221DOI Listing
September 2013

Impact of medical and surgical intervention on survival in patients with cholangiocarcinoma.

World J Gastrointest Surg 2013 Jun;5(6):178-86

Amanda K Arrington, Rebecca L Wiatrek, Gagandeep Singh, Joseph Kim, Division of Surgical Oncology, City of Hope Comprehensive Cancer Center, Duarte, CA 91010, United States.

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http://dx.doi.org/10.4240/wjgs.v5.i6.178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750129PMC
June 2013

The evolving role of VEGF-targeted therapies in the treatment of metastatic colorectal cancer.

Authors:
Marwan Fakih

Expert Rev Anticancer Ther 2013 Apr 22;13(4):427-38. Epub 2013 Feb 22.

Medical Oncology, City of Hope, 1500 Duarte Rd, Duarte, CA 91010, USA.

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http://dx.doi.org/10.1586/era.13.20DOI Listing
April 2013

Targeting mechanisms of resistance to anti-EGF receptor therapy in KRAS wild-type colorectal cancer: the path to more personalized medicine.

Authors:
Marwan Fakih

Future Oncol 2013 Apr;9(4):551-60

City of Hope, 1500 E Duarte Road, Building 51, Room 127, Duarte, CA 91010, USA.

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http://dx.doi.org/10.2217/fon.12.204DOI Listing
April 2013

Intensive radiographic and biomarker surveillance in stage II and III colorectal cancer.

Oncology 2012 26;82(1):41-7. Epub 2012 Jan 26.

Department of Medicine, Roswell Park Cancer Institute, Buffalo, N.Y., USA.

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http://dx.doi.org/10.1159/000333855DOI Listing
April 2012

Single-agent paclitaxel in advanced anal cancer after failure of cisplatin and 5-fluorouracil chemotherapy.

Anticancer Res 2011 Dec;31(12):4637-40

Internal Medicine Department, University at Buffalo, Buffalo, NY, USA.

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December 2011

First-line cisplatin plus etoposide in high-grade metastatic neuroendocrine tumors of colon and rectum (MCRC NET): review of 8 cases.

Anticancer Res 2011 Mar;31(3):975-8

GI Oncology, Department of Medicine, Roswell Park Cancer Institute, Elm and Carlton streets, Buffalo, NY 14263, USA.

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March 2011

Making sense of anti-EGFR plus oxaliplatin-based therapy in the first-line treatment of metastatic colorectal cancer.

Authors:
Marwan G Fakih

Future Oncol 2011 Feb;7(2):223-6

University at Buffalo & Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.2217/fon.10.181DOI Listing
February 2011

Serological immune responses to influenza vaccine in patients with colorectal cancer.

Cancer Chemother Pharmacol 2011 Jan 5;67(1):111-5. Epub 2010 Mar 5.

Department of Medicine, Roswell Park Cancer Institute, Elm and Carlton, Buffalo, NY 14221, USA.

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http://dx.doi.org/10.1007/s00280-010-1292-2DOI Listing
January 2011

Stop and go FOLFOX plus bevacizumab chemotherapy in the first-line treatment of metastatic colorectal cancer.

Oncology 2010 12;79(1-2):67-71. Epub 2010 Nov 12.

Department of Internal Medicine, University at Buffalo, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.1159/000319549DOI Listing
January 2011

5-FU-induced hyperammonemic encephalopathy in a case of metastatic rectal adenocarcinoid successfully rechallenged with the fluoropyrimidine analog, capecitabine.

Anticancer Res 2011 Jan;31(1):335-8

Roswell Park Cancer Institute, Buffalo, NY 14203, USA.

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January 2011

Predictive or non-predictive, prognostic or non-prognostic: Dilemmas generated through small retrospective studies.

Authors:
Marwan Fakih

J Gastrointest Oncol 2010 Dec;1(2):72-3

Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY.

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http://dx.doi.org/10.3978/j.issn.2078-6891.2010.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397576PMC
December 2010

Management of stage II/III rectal cancer.

J Gastrointest Oncol 2010 Dec;1(2):112-9

Department of Radiology, Tripler Army Medical Center, Honolulu, HI.

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http://dx.doi.org/10.3978/j.issn.2078-6891.2010.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397578PMC
December 2010

Positron emission tomography as predictor of rectal cancer response during or following neoadjuvant chemoradiation.

World J Gastrointest Oncol 2010 May;2(5):213-7

Shane Hopkins, Gary Y Yang, Department of Radiation Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, United States.

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http://dx.doi.org/10.4251/wjgo.v2.i5.213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998836PMC
May 2010

Management of anal cancer in 2010. Part 1: Overview, screening, and diagnosis.

Oncology (Williston Park) 2010 Apr;24(4):364-9

School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA.

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April 2010

Management of anal cancer in 2010. Part 2: current treatment standards and future directions.

Oncology (Williston Park) 2010 Apr;24(5):417-24

School of Medicine and Biomedical Sciences, State University of New York at Buffalo, USA.

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April 2010

KRAS mutation screening in colorectal cancer: From paper to practice.

Authors:
Marwan M Fakih

Clin Colorectal Cancer 2010 Jan;9(1):22-30

Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.3816/CCC.2010.n.003DOI Listing
January 2010

A phase I and pharmacokinetics study of intravenous calcitriol in combination with oral dexamethasone and gefitinib in patients with advanced solid tumors.

Cancer Chemother Pharmacol 2009 Dec 26;65(1):33-40. Epub 2009 Apr 26.

Department of Medicine, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.1007/s00280-009-1000-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746253PMC
December 2009

A case of 5-fluorouracil-induced acute psychosis.

Clin Colorectal Cancer 2009 Jul;8(3):166-8

Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

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http://dx.doi.org/10.3816/CCC.2009.n.027DOI Listing
July 2009

Spontaneous regression of colorectal cancer metastatic to retroperitoneal lymph nodes.

Anticancer Res 2009 Feb;29(2):465-8

Departments of Medicine, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

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February 2009

Treating rectal cancer: key issues reconsidered.

Authors:
Marwan Fakih

Oncology (Williston Park) 2008 Nov;22(12):1444-6

Roswell Park Cancer Institute, Buffalo, New York, USA.

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November 2008