Publications by authors named "Martine F Roussel"

95Publications

An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling.

Cancer Res 2020 04 16;80(7):1524-1537. Epub 2020 Jan 16.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1158/0008-5472.CAN-19-2054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416697PMC
April 2020

Preclinical Models of Craniospinal Irradiation for Medulloblastoma.

Cancers (Basel) 2020 Jan 5;12(1). Epub 2020 Jan 5.

Departments of Radiation Oncology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.3390/cancers12010133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016884PMC
January 2020

Modeling pediatric medulloblastoma.

Brain Pathol 2020 05 17;30(3):703-712. Epub 2019 Dec 17.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105.

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http://dx.doi.org/10.1111/bpa.12803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317774PMC
May 2020

CNS penetration and pharmacodynamics of the CHK1 inhibitor prexasertib in a mouse Group 3 medulloblastoma model.

Eur J Pharm Sci 2020 Jan 25;142:105106. Epub 2019 Oct 25.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 28105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2019.105106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925336PMC
January 2020

Women in cancer research.

Nat Rev Cancer 2019 10 15;19(10):547-552. Epub 2019 Aug 15.

Department of Biochemistry and Molecular Biology, John Hopkins School of Public Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41568-019-0176-yDOI Listing
October 2019

A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma.

Clin Cancer Res 2019 02 28;25(4):1379-1388. Epub 2018 Nov 28.

Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, University of Miami, Miller School of Medicine, Miami, Florida.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-1319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7142219PMC
February 2019

Mouse medulloblastoma driven by CRISPR activation of cellular Myc.

Sci Rep 2018 06 7;8(1):8733. Epub 2018 Jun 7.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1038/s41598-018-24956-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992137PMC
June 2018

The critical role that STAT3 plays in glioma-initiating cells: STAT3 addiction in glioma.

Oncotarget 2018 Apr 24;9(31):22095-22112. Epub 2018 Apr 24.

Department of Pathology and Laboratory Medicine, and Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN, USA.

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http://dx.doi.org/10.18632/oncotarget.25188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955139PMC
April 2018

Development and validation of a sensitive LC MS/MS method for the measurement of the checkpoint kinase 1 inhibitor prexasertib and its application in a cerebral microdialysis study.

J Pharm Biomed Anal 2018 Jul 17;156:97-103. Epub 2018 Apr 17.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jpba.2018.04.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984718PMC
July 2018

A new genetically engineered mouse model of choroid plexus carcinoma.

Biochem Biophys Res Commun 2018 02 12;496(2):568-574. Epub 2018 Jan 12.

Université Côte d'Azur, CNRS, Inserm, iBV, Nice, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X173236
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http://dx.doi.org/10.1016/j.bbrc.2017.11.192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880203PMC
February 2018

Epigenetic Drivers in Pediatric Medulloblastoma.

Cerebellum 2018 02;17(1):28-36

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/s12311-017-0899-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807456PMC
February 2018

mTORC1-Mediated Inhibition of 4EBP1 Is Essential for Hedgehog Signaling-Driven Translation and Medulloblastoma.

Dev Cell 2017 12 2;43(6):673-688.e5. Epub 2017 Nov 2.

Department of Developmental Neurobiology, Neurobiology and Brain Tumor Program, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.10.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736446PMC
December 2017

Exome sequencing analysis of murine medulloblastoma models identifies WDR11 as a potential tumor suppressor in Group 3 tumors.

Oncotarget 2017 Sep 27;8(39):64685-64697. Epub 2017 Jul 27.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.18632/oncotarget.19642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630286PMC
September 2017

Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway.

ACS Chem Biol 2017 09 29;12(9):2436-2447. Epub 2017 Aug 29.

Departments of Hematology, ‡Chemical Biology and Therapeutics, §Tumor Cell Biology, and ∥Computational Biology, St. Jude Children's Research Hospital , Memphis, Tennessee, United States.

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http://dx.doi.org/10.1021/acschembio.7b00527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676454PMC
September 2017

Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype.

Cancer Cell 2016 Apr 31;29(4):508-522. Epub 2016 Mar 31.

Li Ka Shing Centre, CRUK Cambridge Institute, University of Cambridge, Robinson Way, Cambridge CB2 0RE, England. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829447PMC
April 2016

Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors.

J Neurooncol 2016 Jan 30;126(2):225-34. Epub 2015 Oct 30.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105, USA.

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http://dx.doi.org/10.1007/s11060-015-1965-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718940PMC
January 2016

TNF Counterbalances the Emergence of M2 Tumor Macrophages.

Cell Rep 2015 Sep 10;12(11):1902-14. Epub 2015 Sep 10.

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4581986PMC
September 2015

Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation.

PLoS One 2015 19;10(6):e0129642. Epub 2015 Jun 19.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, TN, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0129642PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474721PMC
April 2016

Generation of Atoh1-rtTA transgenic mice: a tool for inducible gene expression in hair cells of the inner ear.

Sci Rep 2014 Nov 3;4:6885. Epub 2014 Nov 3.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105.

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http://dx.doi.org/10.1038/srep06885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217099PMC
November 2014

Role of the miR-17∼92 cluster family in cerebellar and medulloblastoma development.

Biol Open 2014 Jun 13;3(7):597-605. Epub 2014 Jun 13.

Department of Tumor Cell Biology, Danny Thomas Research Center, St Jude Children's Research Hospital, Memphis, TN 38105-3678, USA

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http://dx.doi.org/10.1242/bio.20146734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154296PMC
June 2014

Role of MYC in Medulloblastoma.

Cold Spring Harb Perspect Med 2013 Nov 1;3(11). Epub 2013 Nov 1.

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105.

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http://dx.doi.org/10.1101/cshperspect.a014308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808772PMC
November 2013

Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression.

Cancer Res 2013 Dec 21;73(23):7068-78. Epub 2013 Oct 21.

Authors' Affiliations: Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee; Santaris Pharma, Hørsholm; and Department of Haematology, Aalborg University Hospital, Copenhagen, Denmark.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-0927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857104PMC
December 2013

Miz1 is required to maintain autophagic flux.

Nat Commun 2013 ;4:2535

1] Theodor Boveri Institute, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany [2].

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http://dx.doi.org/10.1038/ncomms3535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084558PMC
May 2014

Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Authors:
Paul A Northcott David J H Shih John Peacock Livia Garzia A Sorana Morrissy Thomas Zichner Adrian M Stütz Andrey Korshunov Jüri Reimand Steven E Schumacher Rameen Beroukhim David W Ellison Christian R Marshall Anath C Lionel Stephen Mack Adrian Dubuc Yuan Yao Vijay Ramaswamy Betty Luu Adi Rolider Florence M G Cavalli Xin Wang Marc Remke Xiaochong Wu Readman Y B Chiu Andy Chu Eric Chuah Richard D Corbett Gemma R Hoad Shaun D Jackman Yisu Li Allan Lo Karen L Mungall Ka Ming Nip Jenny Q Qian Anthony G J Raymond Nina T Thiessen Richard J Varhol Inanc Birol Richard A Moore Andrew J Mungall Robert Holt Daisuke Kawauchi Martine F Roussel Marcel Kool David T W Jones Hendrick Witt Africa Fernandez-L Anna M Kenney Robert J Wechsler-Reya Peter Dirks Tzvi Aviv Wieslawa A Grajkowska Marta Perek-Polnik Christine C Haberler Olivier Delattre Stéphanie S Reynaud François F Doz Sarah S Pernet-Fattet Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Wolfram Scheurlen Charles G Eberhart Michelle Fèvre-Montange Anne Jouvet Ian F Pollack Xing Fan Karin M Muraszko G Yancey Gillespie Concezio Di Rocco Luca Massimi Erna M C Michiels Nanne K Kloosterhof Pim J French Johan M Kros James M Olson Richard G Ellenbogen Karel Zitterbart Leos Kren Reid C Thompson Michael K Cooper Boleslaw Lach Roger E McLendon Darell D Bigner Adam Fontebasso Steffen Albrecht Nada Jabado Janet C Lindsey Simon Bailey Nalin Gupta William A Weiss László Bognár Almos Klekner Timothy E Van Meter Toshihiro Kumabe Teiji Tominaga Samer K Elbabaa Jeffrey R Leonard Joshua B Rubin Linda M Liau Erwin G Van Meir Maryam Fouladi Hideo Nakamura Giuseppe Cinalli Miklós Garami Peter Hauser Ali G Saad Achille Iolascon Shin Jung Carlos G Carlotti Rajeev Vibhakar Young Shin Ra Shenandoah Robinson Massimo Zollo Claudia C Faria Jennifer A Chan Michael L Levy Poul H B Sorensen Matthew Meyerson Scott L Pomeroy Yoon-Jae Cho Gary D Bader Uri Tabori Cynthia E Hawkins Eric Bouffet Stephen W Scherer James T Rutka David Malkin Steven C Clifford Steven J M Jones Jan O Korbel Stefan M Pfister Marco A Marra Michael D Taylor

Nature 2012 Aug;488(7409):49-56

Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.

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http://is.muni.cz/repo/990835/nature11327.pdf
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http://www.nature.com/doifinder/10.1038/nature11327
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http://dx.doi.org/10.1038/nature11327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683624PMC
August 2012

A mouse model of the most aggressive subgroup of human medulloblastoma.

Cancer Cell 2012 Feb;21(2):168-80

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.ccr.2011.12.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3285412PMC
February 2012

Medulloblastoma: advances and challenges.

F1000 Biol Rep 2011 1;3. Epub 2011 Mar 1.

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http://dx.doi.org/10.3410/B3-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100785PMC
July 2011

Intrinsic disorder mediates the diverse regulatory functions of the Cdk inhibitor p21.

Nat Chem Biol 2011 Apr 27;7(4):214-21. Epub 2011 Feb 27.

Departments of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1038/nchembio.536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3124363PMC
April 2011

Development and cancer of the cerebellum.

Trends Neurosci 2011 Mar;34(3):134-42

Laboratory of Developmental Neurobiology, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1016/j.tins.2011.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051031PMC
March 2011

Cerebellum development and medulloblastoma.

Curr Top Dev Biol 2011 ;94:235-82

Department of Tumor Cell Biology and Genetics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://linkinghub.elsevier.com/retrieve/pii/B978012380916200
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http://dx.doi.org/10.1016/B978-0-12-380916-2.00008-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213765PMC
April 2011

E2f1-3 are critical for myeloid development.

J Biol Chem 2011 Feb 28;286(6):4783-95. Epub 2010 Nov 28.

College of Medicine and Public Health, Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1074/jbc.M110.182733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039366PMC
February 2011

New concepts in organ site research on medulloblastoma: genetics and genomics.

Future Oncol 2010 Aug;6(8):1229-31

St Jude Children's Research Hospital, Department of Genetics & Tumor Cell Biology, Memphis, TN 38105, USA.

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http://dx.doi.org/10.2217/fon.10.86DOI Listing
August 2010

Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells.

Cancer Res 2010 Jul 1;70(13):5618-27. Epub 2010 Jun 1.

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-3740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896438PMC
July 2010

Inhibition of Hsp90 via 17-DMAG induces apoptosis in a p53-dependent manner to prevent medulloblastoma.

Proc Natl Acad Sci U S A 2009 Oct 23;106(40):17037-42. Epub 2009 Sep 23.

Department of Genetics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1073/pnas.0902880106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761355PMC
October 2009

The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma.

Proc Natl Acad Sci U S A 2009 Feb 5;106(8):2812-7. Epub 2009 Feb 5.

Department of Genetics and Tumor Cell Biology, Saint Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1073/pnas.0809579106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636735PMC
February 2009

Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma.

Mol Cancer Res 2009 Jan;7(1):33-40

Department of Genetics and Tumor Cell Biology, Mail Stop no. 350, 262 Danny Thomas Place, Memphis, TN 38105-3678, USA.

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http://mcr.aacrjournals.org/lookup/doi/10.1158/1541-7786.MCR
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http://dx.doi.org/10.1158/1541-7786.MCR-08-0369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637533PMC
January 2009

Differential post-transcriptional regulation of two Ink4 proteins, p18 Ink4c and p19 Ink4d.

Cell Cycle 2008 Dec 13;7(23):3737-46. Epub 2008 Dec 13.

Department of Tumor Cell Biology and Genetics, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628444PMC
http://dx.doi.org/10.4161/cc.7.23.7187DOI Listing
December 2008

Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.

Biochemistry 2008 Aug 25;47(34):8961-9. Epub 2008 Jul 25.

Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1021/bi800604cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587436PMC
August 2008

Post-transcriptional down-regulation of Atoh1/Math1 by bone morphogenic proteins suppresses medulloblastoma development.

Genes Dev 2008 Mar;22(6):722-7

Departments of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1101/gad.1636408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275424PMC
March 2008

N-myc coordinates retinal growth with eye size during mouse development.

Genes Dev 2008 Jan;22(2):179-93

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1101/gad.1608008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2192753PMC
January 2008

N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development.

Proc Natl Acad Sci U S A 2006 Aug 24;103(31):11579-83. Epub 2006 Jul 24.

Department of Genetics and Tumor Cell Biology, Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1073/pnas.0604727103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1518798PMC
August 2006

Statistical significance threshold criteria for analysis of microarray gene expression data.

Stat Appl Genet Mol Biol 2004 19;3:Article36. Epub 2004 Dec 19.

Department of Biostatistics, St. Jude Children's Research Hospital.

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http://dx.doi.org/10.2202/1544-6115.1064DOI Listing
May 2006

Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia.

Proc Natl Acad Sci U S A 2006 Apr 17;103(17):6688-93. Epub 2006 Apr 17.

Department of Hematology-Oncology, St. Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1073/pnas.0602030103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1440588PMC
April 2006

The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma.

Cell Cycle 2006 Feb 15;5(4):363-5. Epub 2006 Feb 15.

Department of Genetics & Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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https://www.tandfonline.com/doi/full/10.4161/cc.5.4.2475
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http://dx.doi.org/10.4161/cc.5.4.2475DOI Listing
February 2006

Monoclonal antibodies to the mouse p19(Arf) tumor suppressor protein.

Hybrid Hybridomics 2004 Oct;23(5):293-300

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1089/hyb.2004.23.293DOI Listing
October 2004

A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.

Nat Struct Mol Biol 2004 Oct 7;11(10):927-35. Epub 2004 Sep 7.

Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1038/nsmb826DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862556PMC
October 2004

N-terminal polyubiquitination and degradation of the Arf tumor suppressor.

Genes Dev 2004 Aug;18(15):1862-74

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1101/gad.1213904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC517406PMC
August 2004

Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture.

J Cell Biol 2004 Apr;165(2):263-73

Dept. of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA.

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http://dx.doi.org/10.1083/jcb.200309102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172030PMC
April 2004

Histone deacetylase inhibitors activate INK4d gene through Sp1 site in its promoter.

Oncogene 2004 Jul;23(31):5340-9

Department of Molecular-Targeting Cancer Prevention, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.

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http://dx.doi.org/10.1038/sj.onc.1207689DOI Listing
July 2004

Arf tumor suppressor promoter monitors latent oncogenic signals in vivo.

Proc Natl Acad Sci U S A 2003 Dec 9;100(26):15930-5. Epub 2003 Dec 9.

Departments of Genetics and Tumor Cell Biology, St Jude Children's Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1073/pnas.2536808100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC307670PMC
December 2003

A molecular fingerprint for medulloblastoma.

Cancer Res 2003 Sep;63(17):5428-37

Department of Genetics and Tumor Cell Biology, Saint Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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September 2003

Hemangiosarcomas, medulloblastomas, and other tumors in Ink4c/p53-null mice.

Cancer Res 2003 Sep;63(17):5420-7

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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September 2003

Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d.

Nat Cell Biol 2003 May;5(5):422-6

Gonda Department of Cell and Molecular Biology, House Ear Institute, 2100 W. 3rd St., Fifth Floor, Los Angeles, CA 90057, USA.

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http://www.nature.com/articles/ncb976
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http://dx.doi.org/10.1038/ncb976DOI Listing
May 2003

Oncogenic potential of the c-FMS proto-oncogene (CSF-1 receptor).

Cell Cycle 2003 Jan-Feb;2(1):5-6

Dept. of Genetics and Tumor Cell Biology, Howard Hughes Medical Institute, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA

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http://www.tandfonline.com/doi/abs/10.4161/cc.2.1.295
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http://dx.doi.org/10.4161/cc.2.1.295DOI Listing
August 2003

Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing.

Mol Cell 2003 Feb;11(2):415-24

Howard Hughes Medical Institute, St. Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN 38105, USA.

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http://www.cell.com/molecular-cell/pdf/S1097-2765(03)00057-1
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http://dx.doi.org/10.1016/s1097-2765(03)00057-1DOI Listing
February 2003

Arf induces p53-dependent and -independent antiproliferative genes.

Cancer Res 2003 Mar;63(5):1046-53

Department of Genetics and Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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March 2003

p53: regular or super?

Cancer Cell 2002 Dec;2(6):434-5

Department of Genetics and Tumor Cell Biology, Danny Thomas Research Tower, 5006C, St Jude Children's Research Hospital, 332 North Lauderdale Street, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/s1535-6108(02)00216-7DOI Listing
December 2002

The cyclin-dependent kinase inhibitors p19(Ink4d) and p27(Kip1) are coexpressed in select retinal cells and act cooperatively to control cell cycle exit.

Mol Cell Neurosci 2002 Mar;19(3):359-74

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, 332 North Lauderdale Street, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1006/mcne.2001.1090DOI Listing
March 2002

The RING domain of Mdm2 can inhibit cell proliferation.

Cancer Res 2002 Feb;62(4):1222-30

Department of Tumor Cell Biology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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February 2002