Publications by authors named "Martina Severa"

45Publications

Three Decades of Interferon-β in Multiple Sclerosis: Can We Repurpose This Information for the Management of SARS-CoV2 Infection?

Front Immunol 2020 18;11:1459. Epub 2020 Jun 18.

Department of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2020.01459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7326001PMC
August 2020

Interferon-β therapy specifically reduces pathogenic memory B cells in multiple sclerosis patients by inducing a FAS-mediated apoptosis.

Immunol Cell Biol 2016 10 6;94(9):886-894. Epub 2016 Jun 6.

Department of Infectious, Parasitic and Immune-mediated Disease, Istituto Superiore di Sanità, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/icb.2016.55DOI Listing
October 2016

IFN-α promotes rapid human Treg contraction and late Th1-like Treg decrease.

J Leukoc Biol 2016 09 26;100(3):613-23. Epub 2016 Feb 26.

Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Rome, Italy; Istituto Pasteur-Fondazione Cenci Bolognetti, Rome, Italy

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.5A0415-140RDOI Listing
September 2016

Impact of Mycobacterium tuberculosis RD1-locus on human primary dendritic cell immune functions.

Sci Rep 2015 Nov 25;5:17078. Epub 2015 Nov 25.

Department of Infectious, Parasitic and Immune-mediated Diseases; Istituto Superiore di Sanità; Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep17078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658526PMC
November 2015

Dual effect of Thymosin α 1 on human monocyte-derived dendritic cell in vitro stimulated with viral and bacterial toll-like receptor agonists.

Expert Opin Biol Ther 2015 22;15 Suppl 1:S59-70. Epub 2015 Jun 22.

Istituto Superiore di Sanità of Infectious, Parasitic and Immune-mediated Diseases, Viale Regina Elena, Rome, 00151 , Italy +39 06 49903638 ; +39 06 49903638 ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/14712598.2015.1019460DOI Listing
February 2016

IFN-β Therapy Regulates TLR7-Mediated Response in Plasmacytoid Dendritic Cells of Multiple Sclerosis Patients Influencing an Anti-Inflammatory Status.

J Interferon Cytokine Res 2015 Sep 29;35(9):668-81. Epub 2015 Apr 29.

1 Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità , Rome, Italy .

View Article

Download full-text PDF

Source
http://www.liebertpub.com/doi/10.1089/jir.2014.0207
Publisher Site
http://dx.doi.org/10.1089/jir.2014.0207DOI Listing
September 2015

IFN-β and multiple sclerosis: cross-talking of immune cells and integration of immunoregulatory networks.

Cytokine Growth Factor Rev 2015 Apr 22;26(2):229-39. Epub 2014 Nov 22.

Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cytogfr.2014.11.005DOI Listing
April 2015

Pro- and anti-inflammatory cytokines in tuberculosis: a two-edged sword in TB pathogenesis.

Semin Immunol 2014 Dec 8;26(6):543-51. Epub 2014 Nov 8.

Department of Infectious, Parasitic and Immune-mediated diseases, Istituto Superiore di Sanità, 00161 Rome, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.smim.2014.09.011DOI Listing
December 2014

A human dendritic cell-based in vitro model to assess Mycobacterium tuberculosis SO2 vaccine immunogenicity.

ALTEX 2014 20;31(4):397-406. Epub 2014 May 20.

Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14573/altex.1311041DOI Listing
August 2015

The transcriptional repressor BLIMP1 curbs host defenses by suppressing expression of the chemokine CCL8.

J Immunol 2014 Mar 29;192(5):2291-304. Epub 2014 Jan 29.

Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1301799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943885PMC
March 2014

IFN-β therapy modulates B-cell and monocyte crosstalk via TLR7 in multiple sclerosis patients.

Eur J Immunol 2013 Jul 28;43(7):1963-72. Epub 2013 May 28.

Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201243212DOI Listing
July 2013

Epstein-Barr virus persistence and infection of autoreactive plasma cells in synovial lymphoid structures in rheumatoid arthritis.

Ann Rheum Dis 2013 Sep 25;72(9):1559-68. Epub 2012 Dec 25.

Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University of London, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/annrheumdis-2012-202352DOI Listing
September 2013

EBV stimulates TLR- and autophagy-dependent pathways and impairs maturation in plasmacytoid dendritic cells: implications for viral immune escape.

Eur J Immunol 2013 Jan 30;43(1):147-58. Epub 2012 Oct 30.

Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201242552DOI Listing
January 2013

Bystander inhibition of dendritic cell differentiation by Mycobacterium tuberculosis-induced IL-10.

Immunol Cell Biol 2011 Mar 31;89(3):437-46. Epub 2010 Aug 31.

Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/icb.2010.106DOI Listing
March 2011

Superior immunogenicity of inactivated whole virus H5N1 influenza vaccine is primarily controlled by Toll-like receptor signalling.

PLoS Pathog 2008 Aug 29;4(8):e1000138. Epub 2008 Aug 29.

Department of Medical Microbiology, Molecular Virology Section, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.ppat.1000138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516931PMC
August 2008

IFN-beta modulates the response to TLR stimulation in human DC: involvement of IFN regulatory factor-1 (IRF-1) in IL-27 gene expression.

Eur J Immunol 2007 Dec;37(12):3499-508

Department of Infectious, Parasitic and Immune-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.200737566DOI Listing
December 2007

In vitro infection of human dendritic cells by Aspergillus fumigatus conidia triggers the secretion of chemokines for neutrophil and Th1 lymphocyte recruitment.

Microbes Infect 2007 Jul 11;9(8):971-80. Epub 2007 Apr 11.

Department of Infectious, Parasitic, and Immuno-mediated Diseases, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.micinf.2007.03.015DOI Listing
July 2007

Sensitization to TLR7 agonist in IFN-beta-preactivated dendritic cells.

J Immunol 2007 May;178(10):6208-16

Department of Infectious, Parasitic, and Immuno-Mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.178.10.6208DOI Listing
May 2007

NF-{kappa}B is required for STAT-4 expression during dendritic cell maturation.

J Leukoc Biol 2007 Jan 17;81(1):355-63. Epub 2006 Oct 17.

Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, 00161 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0506319DOI Listing
January 2007

Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1.

J Biol Chem 2006 Sep 18;281(36):26188-95. Epub 2006 Jul 18.

Division of Infectious Disease and Immunology, Department of Medicine, The University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M604516200
Publisher Site
http://dx.doi.org/10.1074/jbc.M604516200DOI Listing
September 2006

Pin-ning down immune responses to RNA viruses.

Nat Immunol 2006 Jun;7(6):555-7

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni0606-555DOI Listing
June 2006

Differential responsiveness to IFN-alpha and IFN-beta of human mature DC through modulation of IFNAR expression.

J Leukoc Biol 2006 Jun 19;79(6):1286-94. Epub 2006 Apr 19.

Department of Infectious, Parasitic and Immune-Mediated Diseases, Istituto Superiore di Sanità, 00161 Rome, Italy.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1189/jlb.1205742
Publisher Site
http://dx.doi.org/10.1189/jlb.1205742DOI Listing
June 2006

Inhibition of interleukin-12 expression in diltiazem-treated dendritic cells through the reduction of nuclear factor-kappa B transcriptional activity.

Biochem Pharmacol 2005 Feb 9;69(3):425-32. Epub 2004 Dec 9.

Department of Infectious, Parasitic, and Immunomediated Diseases, Istituto Superiore di Sanità, Rome I-00161, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bcp.2004.10.004DOI Listing
February 2005