Publications by authors named "Martina Schmidt"

100Publications

Prevalence and severity of long-term physical, emotional, and cognitive fatigue across 15 different cancer entities.

Cancer Med 2020 Nov 7;9(21):8053-8061. Epub 2020 Sep 7.

Division of Physical Activity, Prevention and Cancer, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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November 2020

Knowledge, perceptions, and management of cancer-related fatigue: the patients' perspective.

Support Care Cancer 2020 Aug 29. Epub 2020 Aug 29.

Division of Physical Activity, Prevention and Cancer, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.

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August 2020

Resistance Exercise Modulates Kynurenine Pathway in Pancreatic Cancer Patients.

Int J Sports Med 2021 Jan 24;42(1):33-40. Epub 2020 Jul 24.

Division of Physical Activity, Prevention and Cancer, Deutsches Krebsforschungszentrum, Heidelberg, Germany.

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January 2021

Phosphodiesterase isoforms and cAMP compartments in the development of new therapies for obstructive pulmonary diseases.

Curr Opin Pharmacol 2020 04 1;51:34-42. Epub 2020 Jul 1.

Department of Biomedical and Pharmaceutical Sciences, Chapman University School of Pharmacy, Irvine, CA, USA. Electronic address:

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April 2020

Nanodomains in cardiopulmonary disorders and the impact of air pollution.

Biochem Soc Trans 2020 Jun 29. Epub 2020 Jun 29.

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.

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June 2020

Comparison of subjectively and objectively assessed sleep problems in breast cancer patients starting neoadjuvant chemotherapy.

Support Care Cancer 2021 Feb 19;29(2):1015-1023. Epub 2020 Jun 19.

Division of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT) Heidelberg, Im Neuenheimer Feld 460, 69120, Heidelberg, Germany.

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February 2021

Role of the Ang2-Tie2 Axis in Vascular Damage Driven by High Glucose or Nucleoside Diphosphate Kinase B Deficiency.

Int J Mol Sci 2020 May 25;21(10). Epub 2020 May 25.

Experimental Pharmacology Mannheim, European Center for Angioscience, Medical Faculty Mannheim, Heidelberg University, 68167 Mannheim, Germany.

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May 2020

SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in C. elegans.

Cell Death Dis 2020 04 23;11(4):263. Epub 2020 Apr 23.

Faculty of Science and Engineering, Department of Molecular Pharmacology, Groningen Research Institute of Pharmacy (GRIP), University of Groningen, 9713 AV, Groningen, The Netherlands.

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April 2020

SK channel activation potentiates auranofin-induced cell death in glio- and neuroblastoma cells.

Biochem Pharmacol 2020 01 15;171:113714. Epub 2019 Nov 15.

Faculty of Science and Engineering, Department of Molecular Pharmacology, Groningen Research Institute of Pharmacy (GRIP), University of Groningen, 9713 AV Groningen, the Netherlands. Electronic address:

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January 2020

Pre- to postdiagnosis leisure-time physical activity and prognosis in postmenopausal breast cancer survivors.

Breast Cancer Res 2019 11 7;21(1):117. Epub 2019 Nov 7.

Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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November 2019

Cigarette smoke exposure alters phosphodiesterases in human structural lung cells.

Am J Physiol Lung Cell Mol Physiol 2020 01 30;318(1):L59-L64. Epub 2019 Oct 30.

University of Groningen, Department of Molecular Pharmacology, Groningen, The Netherlands.

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January 2020

Resistance Exercise Reduces Kynurenine Pathway Metabolites in Breast Cancer Patients Undergoing Radiotherapy.

Front Oncol 2019 25;9:962. Epub 2019 Sep 25.

Division of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.

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September 2019

Revealing the Virulence Potential of Clinical and Environmental Isolates Using Whole-Genome Sequencing.

Front Microbiol 2019 4;10:1970. Epub 2019 Sep 4.

University of Groningen, University Medical Center Groningen, Department of Medical Microbiology and Infection Prevention, Groningen, Netherlands.

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September 2019

cAMP guided his way: a life for G protein-mediated signal transduction and molecular pharmacology-tribute to Karl H. Jakobs.

Naunyn Schmiedebergs Arch Pharmacol 2019 08 17;392(8):887-911. Epub 2019 May 17.

Experimental Pharmacology Mannheim (EPM), European Center for Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Ludolf-Krehl-Str. 13 - 17, 68167, Mannheim, Germany.

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August 2019

Second M muscarinic receptor binding site contributes to bronchoprotection by tiotropium.

Br J Pharmacol 2019 08 2;176(16):2864-2876. Epub 2019 Jul 2.

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.

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August 2019

Return to work after breast cancer: The role of treatment-related side effects and potential impact on quality of life.

Eur J Cancer Care (Engl) 2019 Jul 29;28(4):e13051. Epub 2019 Apr 29.

Division of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.

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July 2019

Effects of physical and mind-body exercise on sleep problems during and after breast cancer treatment: a systematic review and meta-analysis.

Breast Cancer Res Treat 2019 Jul 6;176(1):1-15. Epub 2019 Apr 6.

Division of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ), National Center for Tumor Diseases (NCT) Heidelberg, Im Neuenheimer Feld 460, 69120, Heidelberg, Germany.

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July 2019

Mental health problems and school performance in first graders: results of the prospective cohort study ikidS.

Eur Child Adolesc Psychiatry 2019 Oct 26;28(10):1341-1352. Epub 2019 Feb 26.

Division of Paediatric Epidemiology, Institute of Medical Biostatistics, Epidemiology, and Informatics, University Medical Centre of the Johannes Gutenberg-University, Obere Zahlbacher Str. 69, 55131, Mainz, Germany.

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October 2019

Phosphodiesterases as therapeutic targets for respiratory diseases.

Pharmacol Ther 2019 05 10;197:225-242. Epub 2019 Feb 10.

Department of Molecular Pharmacology, University of Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, GRIAC, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

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May 2019

Achieving Complete Remission of Hepatocellular Carcinoma: A Significant Predictor for Recurrence-Free Survival after Liver Transplantation.

Can J Gastroenterol Hepatol 2019 8;2019:5796074. Epub 2019 Jan 8.

Department of Medicine B for Gastroenterology and Hepatology, University Hospital Muenster, 48149 Muenster, Germany.

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June 2019

Function of cAMP scaffolds in obstructive lung disease: Focus on epithelial-to-mesenchymal transition and oxidative stress.

Br J Pharmacol 2019 07 18;176(14):2402-2415. Epub 2019 Mar 18.

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.

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July 2019

Recommendation for ophthalmic care in German preschool health examination and its adherence: Results of the prospective cohort study ikidS.

PLoS One 2018 3;13(12):e0208164. Epub 2018 Dec 3.

Division of Pediatric Epidemiology, Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany.

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May 2019

Young age at school entry and attention-deficit hyperactivity disorder-related symptoms during primary school: results of a prospective cohort study conducted at German Rudolf Steiner Schools.

BMJ Open 2018 10 10;8(10):e020820. Epub 2018 Oct 10.

Division of Paediatric Epidemiology, Institute of Medical Biostatistics, Epidemiology and Informatics, University Medical Centre of the Johannes Gutenberg-University, Mainz, Germany.

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October 2018

Targeting FRET-Based Reporters for cAMP and PKA Activity Using AKAP79.

Sensors (Basel) 2018 Jul 5;18(7). Epub 2018 Jul 5.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 2JD, UK.

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July 2018

Quality of life, problems, and needs of disease-free breast cancer survivors 5 years after diagnosis.

Qual Life Res 2018 Aug 8;27(8):2077-2086. Epub 2018 May 8.

Division of Physical Activity, Prevention and Cancer, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.

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August 2018

Cigarette smoke up-regulates PDE3 and PDE4 to decrease cAMP in airway cells.

Br J Pharmacol 2018 07 3;175(14):2988-3006. Epub 2018 Jun 3.

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.

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July 2018

PDE8: A Novel Target in Airway Smooth Muscle.

Am J Respir Cell Mol Biol 2018 04;58(4):426-427

1 Department of Molecular Pharmacology University of Groningen Groningen, the Netherlands and.

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April 2018

Chronic health conditions and school performance in first graders: A prospective cohort study.

PLoS One 2018 27;13(3):e0194846. Epub 2018 Mar 27.

Division of Paediatric Epidemiology, Institute of Medical Biostatistics, Epidemiology, and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

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July 2018

Exercise behavior and physical fitness in patients with advanced lung cancer.

Support Care Cancer 2018 Aug 26;26(8):2725-2736. Epub 2018 Feb 26.

Heidelberg University Clinic, Nationales Centrum für Tumorerkrankungen Heidelberg (NCT), Abt. Medizinische Onkologie - AG Onkologische Sport- und Bewegungstherapie, Im Neuenheimer Feld 460, 69120, Heidelberg, Germany.

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August 2018

L-Thyroxine intake as a potential risk factor for the development of fatigue in breast cancer patients undergoing chemotherapy.

Support Care Cancer 2018 Aug 14;26(8):2561-2569. Epub 2018 Feb 14.

Division of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 460, 69120, Heidelberg, Germany.

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August 2018

Epac Function and cAMP Scaffolds in the Heart and Lung.

J Cardiovasc Dev Dis 2018 Feb 3;5(1). Epub 2018 Feb 3.

Department of Molecular Pharmacology, University of Groningen, 9713AV Groningen, The Netherlands.

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February 2018

cAMP: From Long-Range Second Messenger to Nanodomain Signalling.

Trends Pharmacol Sci 2018 02 27;39(2):209-222. Epub 2017 Dec 27.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK. Electronic address:

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February 2018

Effects of physical exercise on markers of inflammation in breast cancer patients during adjuvant chemotherapy.

Breast Cancer Res Treat 2018 Apr 12;168(2):421-431. Epub 2017 Dec 12.

Division of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.

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April 2018

Determinants of physical, affective, and cognitive fatigue during breast cancer therapy and 12 months follow-up.

Int J Cancer 2018 03 13;142(6):1148-1157. Epub 2017 Nov 13.

Division of Physical Activity, Prevention and Cancer, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ); Im Neuenheimer Feld 581, Heidelberg, 69120, Germany.

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March 2018

Paving the Rho in cancer metastasis: Rho GTPases and beyond.

Pharmacol Ther 2018 03 11;183:1-21. Epub 2017 Sep 11.

Department of Molecular Pharmacology, University of Groningen, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, GRIAC, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

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March 2018

Upregulation of Epac-1 in Hepatic Stellate Cells by Prostaglandin E in Liver Fibrosis Is Associated with Reduced Fibrogenesis.

J Pharmacol Exp Ther 2017 11 1;363(2):126-135. Epub 2017 Sep 1.

Groningen Research Institute for Pharmacy, Department of Pharmacokinetics, Toxicology and Targeting (M.S., L.B., E.P., C.R.-S., K.P.), and Groningen Research Institute for Pharmacy, Department of Molecular Pharmacology (B.H., P.M.-L., M.S.), University of Groningen, Groningen, The Netherlands; and INSERM U1149, Center for Research on Inflammation, Université Paris Diderot, Paris, France (S.L.)

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November 2017

Elevated intrathymic sphingosine-1-phosphate promotes thymus involution during sepsis.

Mol Immunol 2017 10 30;90:255-263. Epub 2017 Aug 30.

Institute of Biochemistry I - Pathobiochemistry, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine & Pharmacology TMP, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany. Electronic address:

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October 2017

Endothelial follistatin-like-1 regulates the postnatal development of the pulmonary vasculature by modulating BMP/Smad signaling.

Pulm Circ 2017 Mar 15;7(1):219-231. Epub 2017 Mar 15.

University of Groningen, Department of Molecular Pharmacology, Groningen Research Institute for Asthma and COPD, Groningen, The Netherlands.

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March 2017

Impact of HSCT Conditioning and Glucocorticoid Dose on Exercise Adherence and Response.

Med Sci Sports Exerc 2017 Nov;49(11):2143-2150

1Department of Medical Oncology, National Center for Tumor Diseases (NCT) and Heidelberg University Hospital, Heidelberg, GERMANY; 2Division of Physical Activity, Prevention and Cancer, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Heidelberg, GERMANY; 3Bone Marrow Transplant Unit, German Clinic for Diagnostics, Wiesbaden, GERMANY; 4Department of Medicine V, Heidelberg University Hospital, Heidelberg, GERMANY; 5Central Institute of Mental Health, Mannheim, GERMANY; and 6Faculty of Health, University of Antwerp, BELGIUM.

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November 2017

The PDE4 inhibitor CHF-6001 and LAMAs inhibit bronchoconstriction-induced remodeling in lung slices.

Am J Physiol Lung Cell Mol Physiol 2017 Sep 8;313(3):L507-L515. Epub 2017 Jun 8.

Department of Molecular Pharmacology, University of Groningen, The Netherlands.

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September 2017

Catecholamines facilitate VEGF-dependent angiogenesis via β2-adrenoceptor-induced Epac1 and PKA activation.

Oncotarget 2017 Jul;8(27):44732-44748

Institute of Experimental and Clinical Pharmacology and Toxicology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.

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July 2017

The microRNA-7-mediated reduction in EPAC-1 contributes to vascular endothelial permeability and eNOS uncoupling in murine experimental retinopathy.

Acta Diabetol 2017 Jun 28;54(6):581-591. Epub 2017 Mar 28.

International Research and Training Network on Diabetic Microvascular Complications (GRK1874/DIAMICOM), University of Heidelberg, Heidelberg, Germany.

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June 2017

Effects of exercise on sleep problems in breast cancer patients receiving radiotherapy: a randomized clinical trial.

Breast Cancer Res Treat 2017 04 8;162(3):489-499. Epub 2017 Feb 8.

Division of Physical Activity, Prevention and Cancer, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 460, 69120, Heidelberg, Germany.

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April 2017

Microtubule-regulating proteins and cAMP-dependent signaling in neuroblastoma differentiation.

Cytoskeleton (Hoboken) 2017 Mar 13;74(3):143-158. Epub 2017 Feb 13.

Laboratory of Cell and Neuronal Dynamics, Department of Biology, Faculty of Sciences, Universidad de Chile, Santiago, Chile.

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March 2017

Self-reported physical activity behavior of breast cancer survivors during and after adjuvant therapy: 12 months follow-up of two randomized exercise intervention trials.

Acta Oncol 2017 Apr 13;56(4):618-627. Epub 2017 Jan 13.

a Division of Physical Activity, Prevention and Cancer , National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ) , Heidelberg , Germany.

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April 2017

Muscle strength in breast cancer patients receiving different treatment regimes.

J Cachexia Sarcopenia Muscle 2017 Apr 28;8(2):305-316. Epub 2016 Nov 28.

Division of Medical Oncology, National Center for Tumor Diseases (NCT) and University Hospital, Heidelberg, Germany.

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April 2017

Epac1 links prostaglandin E2 to β-catenin-dependent transcription during epithelial-to-mesenchymal transition.

Oncotarget 2016 Jul;7(29):46354-46370

Department of Molecular Pharmacology, Groningen Research Institute for Pharmacy (GRIP), University of Groningen, Groningen, The Netherlands.

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July 2016

Determinants of exercise adherence and contamination in a randomized controlled trial in cancer patients during and after allogeneic HCT.

Support Care Cancer 2016 10 17;24(10):4327-37. Epub 2016 May 17.

Department of Medical Oncology, National Center for Tumor Diseases (NCT) and Heidelberg University Hospital, Im Neuenheimer Feld 460, 69120, Heidelberg, Germany.

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October 2016

Cancer-related fatigue shows a stable association with diurnal cortisol dysregulation in breast cancer patients.

Brain Behav Immun 2016 Feb 9;52:98-105. Epub 2015 Oct 9.

Division of Preventive Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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February 2016

Exchange Protein Directly Activated by cAMP (EPAC) Regulates Neuronal Polarization through Rap1B.

J Neurosci 2015 Aug;35(32):11315-29

Laboratory of Cell and Neuronal Dynamics, Department of Biology, Faculty of Sciences, Universidad de Chile, 7800024 Santiago, Chile,

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August 2015

RhoA Activation Sensitizes Cells to Proteotoxic Stimuli by Abrogating the HSF1-Dependent Heat Shock Response.

PLoS One 2015 20;10(7):e0133553. Epub 2015 Jul 20.

Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands.

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April 2016

β3-Adrenoceptor-mediated relaxation of rat and human urinary bladder: roles of BKCa channels and Rho kinase.

Naunyn Schmiedebergs Arch Pharmacol 2015 Jul 9;388(7):749-59. Epub 2015 May 9.

Department of Molecular Pharmacology, University of Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands,

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July 2015

Factors influencing participation in a randomized controlled resistance exercise intervention study in breast cancer patients during radiotherapy.

BMC Cancer 2015 Mar 27;15:186. Epub 2015 Mar 27.

Unit of Physical Activity and Cancer, Department of Preventive Oncology, German Cancer Research Center and National Center for Tumor Diseases, Im Neuenheimer Feld 460, 69120, Heidelberg, Germany.

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March 2015

Exercise training intensity prescription in breast cancer survivors: validity of current practice and specific recommendations.

J Cancer Surviv 2015 Dec 26;9(4):612-9. Epub 2015 Feb 26.

Department of Preventive Oncology, National Center for Tumor Diseases (NCT) Heidelberg, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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December 2015

A-kinase-anchoring proteins coordinate inflammatory responses to cigarette smoke in airway smooth muscle.

Am J Physiol Lung Cell Mol Physiol 2015 Apr 30;308(8):L766-75. Epub 2015 Jan 30.

University of Groningen, Department of Molecular Pharmacology, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, GRIAC, Groningen, The Netherlands;

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April 2015

Effects of resistance exercise on fatigue and quality of life in breast cancer patients undergoing adjuvant chemotherapy: A randomized controlled trial.

Int J Cancer 2015 Jul 16;137(2):471-80. Epub 2014 Dec 16.

Division of Preventive Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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July 2015

A high transconductance accumulation mode electrochemical transistor.

Adv Mater 2014 Nov 13;26(44):7450-5. Epub 2014 Oct 13.

Department of Bioelectronics, Ecole Nationale Supérieure des Mines, CMP-EMSE, MOC, Gardanne, 13541, France.

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November 2014

Prostaglandin E2 promotes MYCN non-amplified neuroblastoma cell survival via β-catenin stabilization.

J Cell Mol Med 2015 Jan 30;19(1):210-26. Epub 2014 Sep 30.

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands; Department of Paediatrics, Department of Pediatric Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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January 2015

Exercise intensity classification in cancer patients undergoing allogeneic HCT.

Med Sci Sports Exerc 2015 May;47(5):889-95

1Division of Preventive Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center, Heidelberg, GERMANY; 2Department of Medical Oncology, National Center for Tumor Diseases (NCT) and Heidelberg University Hospital, Heidelberg, GERMANY; 3Department of Medicine VII, Heidelberg University Hospital, Heidelberg, GERMANY; 4Department of Medicine V, Heidelberg University Hospital, Heidelberg, GERMANY; 5Institute of Sports and Sport Science, Heidelberg University, Heidelberg, GERMANY; 6Central Institute of Mental Health, Mannheim, GERMANY; and 7Fred Hutchinson Cancer Research Centre, Seattle, WA.

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May 2015

Rat β₃-adrenoceptor protein expression: antibody validation and distribution in rat gastrointestinal and urogenital tissues.

Naunyn Schmiedebergs Arch Pharmacol 2014 Nov 30;387(11):1117-27. Epub 2014 Aug 30.

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands.

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November 2014

Interaction between Epac1 and miRNA-7 in airway smooth muscle cells.

Naunyn Schmiedebergs Arch Pharmacol 2014 Aug 4;387(8):795-7. Epub 2014 Jul 4.

Department of Molecular Pharmacology, University of Groningen, Groningen, The Netherlands,

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August 2014

Cardiorespiratory fitness in breast cancer patients undergoing adjuvant therapy.

Acta Oncol 2014 Oct 16;53(10):1356-65. Epub 2014 May 16.

Preventive Oncology, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ) , Heidelberg , Germany.

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October 2014

TGF-β-activated kinase 1 (TAK1) signaling regulates TGF-β-induced WNT-5A expression in airway smooth muscle cells via Sp1 and β-catenin.

PLoS One 2014 11;9(4):e94801. Epub 2014 Apr 11.

Department of Molecular Pharmacology, University of Groningen, Groningen, the Netherlands; Groningen Research Institute for Asthma and COPD, University of Groningen, Groningen, the Netherlands.

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May 2015

Activin-A: active in inflammation in COPD.

Eur Respir J 2014 Apr;43(4):954-5

University of Groningen, Groningen, the Netherlands.

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April 2014

The pharmacological rationale for combining muscarinic receptor antagonists and β-adrenoceptor agonists in the treatment of airway and bladder disease.

Curr Opin Pharmacol 2014 Jun 27;16:31-42. Epub 2014 Mar 27.

Respiratory Diseases Research and Department of Translational Medicine & Clinical Pharmacology, Boehringer Ingelheim Pharma GmbH, Ingelheim, Germany; Department of Pharmacology, Johannes Gutenberg University, Mainz, Germany. Electronic address:

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June 2014

A-kinase anchoring proteins contribute to loss of E-cadherin and bronchial epithelial barrier by cigarette smoke.

Am J Physiol Cell Physiol 2014 Mar 22;306(6):C585-97. Epub 2014 Jan 22.

University of Groningen, Department of Molecular Pharmacology, Groningen, The Netherlands;

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March 2014

Sphingosine kinase-1 inhibition protects primary rat hepatocytes against bile salt-induced apoptosis.

Biochim Biophys Acta 2013 Dec 28;1832(12):1922-9. Epub 2013 Jun 28.

Dept. of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address:

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December 2013

Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors.

PLoS Genet 2013 27;9(3):e1003284. Epub 2013 Mar 27.

Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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June 2013

Exchange protein directly activated by cAMP (epac): a multidomain cAMP mediator in the regulation of diverse biological functions.

Pharmacol Rev 2013 Apr 27;65(2):670-709. Epub 2013 Feb 27.

Department of Molecular Pharmacology, Groningen Research Institute for Pharmacy, University of Groningen, 9713 AV Groningen, The Netherlands.

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April 2013

Association of pre-diagnosis physical activity with recurrence and mortality among women with breast cancer.

Int J Cancer 2013 Sep 18;133(6):1431-40. Epub 2013 Mar 18.

Unit of Physical Activity and Cancer, Division of Environmental Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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September 2013

Distinct PKA and Epac compartmentalization in airway function and plasticity.

Pharmacol Ther 2013 Feb 23;137(2):248-65. Epub 2012 Oct 23.

Department of Molecular Pharmacology, University Center of Pharmacy, University of Groningen, The Netherlands.

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February 2013

The role of endogenous H2S formation in reversible remodeling of lung tissue during hibernation in the Syrian hamster.

J Exp Biol 2012 Aug;215(Pt 16):2912-9

Department of Clinical Pharmacology, University of Groningen, University Medical Center Groningen, PO Box 196, 9700 RB Groningen, The Netherlands.

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August 2012

Walking, bicycling, and sports in postmenopausal breast cancer survivors--results from a German patient cohort study.

Psychooncology 2013 Jun 16;22(6):1291-8. Epub 2012 Jul 16.

Unit of Physical Activity and Cancer, Division of Environmental Epidemiology, German Cancer Research Center, Heidelberg, Germany.

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June 2013

Induction of VMAT-1 and TPH-1 expression induces vesicular accumulation of serotonin and protects cells and tissue from cooling/rewarming injury.

PLoS One 2012 12;7(1):e30400. Epub 2012 Jan 12.

Department of Clinical Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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May 2012