Publications by authors named "Martin den Heijer"

99Publications

[Hormone treatment of transgender people: Long-term health effects and safety].

Ned Tijdschr Geneeskd 2020 Jul 23;164. Epub 2020 Jul 23.

Amsterdam UMC, locatie VUmc, Amsterdam, afd. Endocrinologie (tevens Kennis- en Zorgcentrum voor Genderdysforie.

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July 2020

Adiposity is a confounding factor which largely explains the association of serum vitamin D concentrations with C-reactive protein, leptin and adiponectin.

Cytokine 2020 Jul 20;131:155104. Epub 2020 Apr 20.

Department of Internal Medicine and Endocrinology, VU University Medical Center, Amsterdam Movement Sciences, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.cyto.2020.155104DOI Listing
July 2020

Sexual Desire Changes in Transgender Individuals Upon Initiation of Hormone Treatment: Results From the Longitudinal European Network for the Investigation of Gender Incongruence.

J Sex Med 2020 Apr 31;17(4):812-825. Epub 2020 Jan 31.

Department of Endocrinology, Ghent University Hospital, Ghent, Belgium; Center for Sexology and Gender, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.jsxm.2019.12.020DOI Listing
April 2020

Frequency, Determinants, and Satisfaction of Breast Augmentation in Trans Women Receiving Hormone Treatment.

J Sex Med 2020 02 2;17(2):342-348. Epub 2019 Dec 2.

Department of Endocrinology, Amsterdam UMC, VU University Medical Center, Amsterdam, the Netherlands; Center of Expertise on Gender Dysphoria, Amsterdam UMC, VU University Medical Center, Amsterdam, the Netherlands; Department of Internal Medicine, Amsterdam UMC, VU University Medical Center, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jsxm.2019.10.021DOI Listing
February 2020

Multiple Sclerosis Patients Show Lower Bioavailable 25(OH)D and 1,25(OH)D, but No Difference in Ratio of 25(OH)D/24,25(OH)D and FGF23 Concentrations.

Nutrients 2019 Nov 15;11(11). Epub 2019 Nov 15.

Department of Clinical Chemistry, Endocrine Laboratory, Amsterdam University Medical Center, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.3390/nu11112774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893545PMC
November 2019

Baseline characteristics of the HAARLEM study: 100 male amateur athletes using anabolic androgenic steroids.

Scand J Med Sci Sports 2020 Mar 21;30(3):531-539. Epub 2019 Nov 21.

Department of Internal Medicine, Spaarne Gasthuis, Haarlem, The Netherlands.

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http://dx.doi.org/10.1111/sms.13592DOI Listing
March 2020

Metabolomics: a search for biomarkers of visceral fat and liver fat content.

Metabolomics 2019 10 5;15(10):139. Epub 2019 Oct 5.

Department of Clinical Epidemiology, Leiden University Medical Center, Postal Zone C7-P, PO Box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s11306-019-1599-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6778586PMC
October 2019

Bone health in adult trans persons: an update of the literature.

Curr Opin Endocrinol Diabetes Obes 2019 12;26(6):296-300

Department of Endocrinology, Center for Sexology and Gender, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1097/MED.0000000000000502DOI Listing
December 2019

Ovariectomy increases RANKL protein expression in bone marrow adipocytes of C3H/HeJ mice.

Am J Physiol Endocrinol Metab 2019 12 17;317(6):E1050-E1054. Epub 2019 Sep 17.

Research Laboratory Bone and Calcium Metabolism, Department of Clinical Chemistry, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Movement Sciences, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1152/ajpendo.00142.2019DOI Listing
December 2019

Fracture Risk in Trans Women and Trans Men Using Long-Term Gender-Affirming Hormonal Treatment: A Nationwide Cohort Study.

J Bone Miner Res 2020 01 7;35(1):64-70. Epub 2019 Oct 7.

Department of Endocrinology, Amsterdam UMC, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1002/jbmr.3862DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7003754PMC
January 2020

Bone geometry and trabecular bone score in transgender people before and after short- and long-term hormonal treatment.

Bone 2019 10 1;127:280-286. Epub 2019 Jul 1.

Department of Internal Medicine, Amsterdam UMC, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, the Netherlands; Center of Expertise on Gender Dysphoria, Amsterdam UMC, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2019.06.029DOI Listing
October 2019

Change in grip strength in trans people and its association with lean body mass and bone density.

Endocr Connect 2019 Jul;8(7):1020-1028

Department of Endocrinology and Center of Expertise on Gender Dysphoria, Amsterdam University Medical Center, Vrije Universiteit, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1530/EC-19-0196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652261PMC
July 2019

Gender-Affirming Hormone Treatment Decreases Bone Turnover in Transwomen and Older Transmen.

J Bone Miner Res 2019 10 19;34(10):1862-1872. Epub 2019 Aug 19.

Department of Internal Medicine and Center of Expertise on Gender Dysphoria, Amsterdam UMC, Vrije Universiteit Amsterdam, A, msterdam, The Netherlands.

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http://dx.doi.org/10.1002/jbmr.3762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6852079PMC
October 2019

Integrative Clinical Ethics Support in Gender Affirmative Care: Lessons Learned.

HEC Forum 2019 Sep;31(3):241-260

Department of Medical Humanities, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10730-019-09376-6DOI Listing
September 2019

Cancer Risk in Transgender People.

Endocrinol Metab Clin North Am 2019 06 23;48(2):441-452. Epub 2019 Mar 23.

Department of Internal Medicine, Amsterdam UMC, VU University Medical Center, Amsterdam, the Netherlands; Center of Expertise on Gender Dysphoria, Amsterdam UMC, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08898529193001
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http://dx.doi.org/10.1016/j.ecl.2019.02.005DOI Listing
June 2019

Gender-Affirming Hormone Treatment Induces Facial Feminization in Transwomen and Masculinization in Transmen: Quantification by 3D Scanning and Patient-Reported Outcome Measures.

J Sex Med 2019 May 26;16(5):746-754. Epub 2019 Mar 26.

Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Internal Medicine, Amsterdam Movement Sciences, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jsxm.2019.02.011DOI Listing
May 2019

Cardiovascular risk in 159 934 frequent blood donors while addressing the healthy donor effect.

Heart 2019 08 14;105(16):1260-1265. Epub 2019 Mar 14.

Department of Donor Medicine Research - Donor Studies, Sanquin Research, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1136/heartjnl-2018-314138DOI Listing
August 2019

Changes of Vitamin D-Binding Protein, and Total, Bioavailable, and Free 25-Hydroxyvitamin D in Transgender People.

J Clin Endocrinol Metab 2019 07;104(7):2728-2734

Department of Internal Medicine, Endocrine Section, and Center of Expertise on Gender Dysphoria, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands.

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http://dx.doi.org/10.1210/jc.2018-02602DOI Listing
July 2019

Occurrence of Acute Cardiovascular Events in Transgender Individuals Receiving Hormone Therapy.

Circulation 2019 03;139(11):1461-1462

Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Department of Internal Medicine, Division of Endocrinology, the Netherlands (N.M.N., C.M.W., C.J.M.d.B., L.J.G.G., M.d.H.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.118.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.038584DOI Listing
March 2019

Associations of different body fat deposits with serum 25-hydroxyvitamin D concentrations.

Clin Nutr 2019 12 18;38(6):2851-2857. Epub 2018 Dec 18.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1016/j.clnu.2018.12.018DOI Listing
December 2019

Cardiometabolic Effects of Testosterone in Transmen and Estrogen Plus Cyproterone Acetate in Transwomen.

J Clin Endocrinol Metab 2019 06;104(6):1937-1947

Division of Endocrinology, Department of Internal Medicine, Amsterdam University Medical Center, De Boelelaan, HV Amsterdam, Netherlands.

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http://dx.doi.org/10.1210/jc.2018-02138DOI Listing
June 2019

Bone Safety During the First Ten Years of Gender-Affirming Hormonal Treatment in Transwomen and Transmen.

J Bone Miner Res 2019 03 7;34(3):447-454. Epub 2018 Dec 7.

Department of Internal Medicine, VU University Medical Center, Amsterdam, the Netherlands.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jbmr.3612
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http://dx.doi.org/10.1002/jbmr.3612DOI Listing
March 2019

The effect of PPARγ inhibition on bone marrow adipose tissue and bone in C3H/HeJ mice.

Am J Physiol Endocrinol Metab 2019 01 20;316(1):E96-E105. Epub 2018 Nov 20.

Amsterdam Movement Sciences, Research Laboratory Bone and Calcium Metabolism, Department of Clinical Chemistry, Vrije Universiteit, Amsterdam University Medical Center , Amsterdam , The Netherlands.

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https://www.physiology.org/doi/10.1152/ajpendo.00265.2018
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http://dx.doi.org/10.1152/ajpendo.00265.2018DOI Listing
January 2019

Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation.

Authors:
Alexander Teumer Layal Chaker Stefan Groeneweg Yong Li Celia Di Munno Caterina Barbieri Ulla T Schultheiss Michela Traglia Tarunveer S Ahluwalia Masato Akiyama Emil Vincent R Appel Dan E Arking Alice Arnold Arne Astrup Marian Beekman John P Beilby Sofie Bekaert Eric Boerwinkle Suzanne J Brown Marc De Buyzere Purdey J Campbell Graziano Ceresini Charlotte Cerqueira Francesco Cucca Ian J Deary Joris Deelen Kai-Uwe Eckardt Arif B Ekici Johan G Eriksson Luigi Ferrrucci Tom Fiers Edoardo Fiorillo Ian Ford Caroline S Fox Christian Fuchsberger Tessel E Galesloot Christian Gieger Martin Gögele Alessandro De Grandi Niels Grarup Karin Halina Greiser Kadri Haljas Torben Hansen Sarah E Harris Diana van Heemst Martin den Heijer Andrew A Hicks Wouter den Hollander Georg Homuth Jennie Hui M Arfan Ikram Till Ittermann Richard A Jensen Jiaojiao Jing J Wouter Jukema Eero Kajantie Yoichiro Kamatani Elisa Kasbohm Jean-Marc Kaufman Lambertus A Kiemeney Margreet Kloppenburg Florian Kronenberg Michiaki Kubo Jari Lahti Bruno Lapauw Shuo Li David C M Liewald Ee Mun Lim Allan Linneberg Michela Marina Deborah Mascalzoni Koichi Matsuda Daniel Medenwald Christa Meisinger Ingrid Meulenbelt Tim De Meyer Henriette E Meyer Zu Schwabedissen Rafael Mikolajczyk Matthijs Moed Romana T Netea-Maier Ilja M Nolte Yukinori Okada Mauro Pala Cristian Pattaro Oluf Pedersen Astrid Petersmann Eleonora Porcu Iris Postmus Peter P Pramstaller Bruce M Psaty Yolande F M Ramos Rajesh Rawal Paul Redmond J Brent Richards Ernst R Rietzschel Fernando Rivadeneira Greet Roef Jerome I Rotter Cinzia F Sala David Schlessinger Elizabeth Selvin P Eline Slagboom Nicole Soranzo Thorkild I A Sørensen Timothy D Spector John M Starr David J Stott Youri Taes Daniel Taliun Toshiko Tanaka Betina Thuesen Daniel Tiller Daniela Toniolo Andre G Uitterlinden W Edward Visser John P Walsh Scott G Wilson Bruce H R Wolffenbuttel Qiong Yang Hou-Feng Zheng Anne Cappola Robin P Peeters Silvia Naitza Henry Völzke Serena Sanna Anna Köttgen Theo J Visser Marco Medici

Nat Commun 2018 10 26;9(1):4455. Epub 2018 Oct 26.

Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-018-06356-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203810PMC
October 2018

Sex differences in body fat distribution are related to sex differences in serum leptin and adiponectin.

Peptides 2018 09 1;107:25-31. Epub 2018 Aug 1.

Department of Clinical Epidemiology, Leiden University Medical Center (LUMC), PO-Box 9600, 2300RC, Leiden, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.peptides.2018.07.008DOI Listing
September 2018

Testosterone, androstenedione, cortisol and cortisone levels in human unstimulated, stimulated and parotid saliva.

Steroids 2018 10 1;138:26-34. Epub 2018 Jun 1.

Endocrine Laboratory, Department of Clinical Chemistry, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.steroids.2018.05.013DOI Listing
October 2018

The osteoblast: Linking glucocorticoid-induced osteoporosis and hyperglycaemia? A post-hoc analysis of a randomised clinical trial.

Bone 2018 07 3;112:173-176. Epub 2018 May 3.

Diabetes Center, Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2018.04.025DOI Listing
July 2018

The occurrence of benign brain tumours in transgender individuals during cross-sex hormone treatment.

Brain 2018 07;141(7):2047-2054

Department of Internal Medicine, Division of Endocrinology, VU University Medical Centre, De Boelelaan, Amsterdam, The Netherlands.

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https://academic.oup.com/brain/article/141/7/2047/4983052
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http://dx.doi.org/10.1093/brain/awy108DOI Listing
July 2018

The Amsterdam Cohort of Gender Dysphoria Study (1972-2015): Trends in Prevalence, Treatment, and Regrets.

J Sex Med 2018 Apr 17;15(4):582-590. Epub 2018 Feb 17.

Department of Endocrinology, VU University Medical Center, Amsterdam, the Netherlands; Center of Expertise on Gender Dysphoria, VU University Medical Center, Amsterdam, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S17436095183005
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http://dx.doi.org/10.1016/j.jsxm.2018.01.016DOI Listing
April 2018

Early Hormonal Treatment Affects Body Composition and Body Shape in Young Transgender Adolescents.

J Sex Med 2018 02;15(2):251-260

Department of Pediatrics, Division of Endocrinology, VU University Medical Center, Amsterdam, The Netherlands; Department of Pediatrics, Division of Pediatric Endocrinology, Ghent University Hospital, Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jsxm.2017.12.009DOI Listing
February 2018

Hyperhomocysteinemia and Risk of First Venous Thrombosis: The Influence of (Unmeasured) Confounding Factors.

Am J Epidemiol 2018 07;187(7):1392-1400

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1093/aje/kwy004DOI Listing
July 2018

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels.

Authors:
Xia Jiang Paul F O'Reilly Hugues Aschard Yi-Hsiang Hsu J Brent Richards Josée Dupuis Erik Ingelsson David Karasik Stefan Pilz Diane Berry Bryan Kestenbaum Jusheng Zheng Jianan Luan Eleni Sofianopoulou Elizabeth A Streeten Demetrius Albanes Pamela L Lutsey Lu Yao Weihong Tang Michael J Econs Henri Wallaschofski Henry Völzke Ang Zhou Chris Power Mark I McCarthy Erin D Michos Eric Boerwinkle Stephanie J Weinstein Neal D Freedman Wen-Yi Huang Natasja M Van Schoor Nathalie van der Velde Lisette C P G M de Groot Anke Enneman L Adrienne Cupples Sarah L Booth Ramachandran S Vasan Ching-Ti Liu Yanhua Zhou Samuli Ripatti Claes Ohlsson Liesbeth Vandenput Mattias Lorentzon Johan G Eriksson M Kyla Shea Denise K Houston Stephen B Kritchevsky Yongmei Liu Kurt K Lohman Luigi Ferrucci Munro Peacock Christian Gieger Marian Beekman Eline Slagboom Joris Deelen Diana van Heemst Marcus E Kleber Winfried März Ian H de Boer Alexis C Wood Jerome I Rotter Stephen S Rich Cassianne Robinson-Cohen Martin den Heijer Marjo-Riitta Jarvelin Alana Cavadino Peter K Joshi James F Wilson Caroline Hayward Lars Lind Karl Michaëlsson Stella Trompet M Carola Zillikens Andre G Uitterlinden Fernando Rivadeneira Linda Broer Lina Zgaga Harry Campbell Evropi Theodoratou Susan M Farrington Maria Timofeeva Malcolm G Dunlop Ana M Valdes Emmi Tikkanen Terho Lehtimäki Leo-Pekka Lyytikäinen Mika Kähönen Olli T Raitakari Vera Mikkilä M Arfan Ikram Naveed Sattar J Wouter Jukema Nicholas J Wareham Claudia Langenberg Nita G Forouhi Thomas E Gundersen Kay-Tee Khaw Adam S Butterworth John Danesh Timothy Spector Thomas J Wang Elina Hyppönen Peter Kraft Douglas P Kiel

Nat Commun 2018 01 17;9(1):260. Epub 2018 Jan 17.

Institute for Aging Research, Hebrew SeniorLife, 1200 Centre Street, Boston, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-02662-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5772647PMC
January 2018

Associations of Abdominal Subcutaneous and Visceral Fat with Insulin Resistance and Secretion Differ Between Men and Women: The Netherlands Epidemiology of Obesity Study.

Metab Syndr Relat Disord 2018 02 17;16(1):54-63. Epub 2018 Jan 17.

1 Department of Clinical Epidemiology, Leiden University Medical Center , Leiden, the Netherlands .

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http://dx.doi.org/10.1089/met.2017.0128DOI Listing
February 2018

Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.

Am J Hum Genet 2018 01;102(1):88-102

Department of Internal Medicine, Erasmus MC, 3000 CA Rotterdam, the Netherlands; The Generation R Study Group, Erasmus MC, 3000 CA Rotterdam, the Netherlands; Department of Epidemiology, Erasmus MC, 3000 CA Rotterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777980PMC
January 2018

Associations of Serum 25(OH)D Concentrations with Lung Function, Airway Inflammation and Common Cold in the General Population.

Nutrients 2018 Jan 3;10(1). Epub 2018 Jan 3.

Department of Internal Medicine and Endocrinology, VU University Medical Center, Amsterdam Movement Sciences, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.3390/nu10010035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5793263PMC
January 2018

Plasma FGF23 is not elevated in prostate cancer.

Clin Chim Acta 2018 Mar 23;478:129-131. Epub 2017 Dec 23.

Department of Clinical Chemistry, Endocrine Laboratory, VU University Medical Center, de Boelelaan 1117, 1081 HV Amsterdam, The Netherlands; Laboratory of Endocrinology, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2017.12.035DOI Listing
March 2018

Long term hormonal treatment for transgender people.

BMJ 2017 11 30;359:j5027. Epub 2017 Nov 30.

Center of expertise on gender dysphoria, VU Medical Center, Amsterdam, Netherlands.

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http://dx.doi.org/10.1136/bmj.j5027DOI Listing
November 2017

Breast Development in Transwomen After 1 Year of Cross-Sex Hormone Therapy: Results of a Prospective Multicenter Study.

J Clin Endocrinol Metab 2018 02;103(2):532-538

Department of Endocrinology and Center of Expertise on Gender Dysphoria, VU University Medical Center, Amsterdam, The Netherlands.

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https://academic.oup.com/jcem/article/103/2/532/4642966
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http://dx.doi.org/10.1210/jc.2017-01927DOI Listing
February 2018

The effect of raloxifene on bone marrow adipose tissue and bone turnover in postmenopausal women with osteoporosis.

Bone 2019 01 11;118:62-68. Epub 2017 Oct 11.

Leiden University Medical Center, Department of Internal Medicine, Albinusdreef 2, PO Box 9600, 2300RC Leiden, The Netherlands; VU University Medical Center, Department of Clinical Chemistry, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S87563282173037
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http://dx.doi.org/10.1016/j.bone.2017.10.011DOI Listing
January 2019

Brain sexual differentiation and effects of cross-sex hormone therapy in transpeople: A resting-state functional magnetic resonance study.

Neurophysiol Clin 2017 Dec 10;47(5-6):361-370. Epub 2017 Oct 10.

Department of medical psychology, neuroscience campus Amsterdam, VU university medical center, De Boelelaan 1117, 1081 HV, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neucli.2017.09.001DOI Listing
December 2017

Brain functional connectivity patterns in children and adolescents with gender dysphoria: Sex-atypical or not?

Psychoneuroendocrinology 2017 Dec 18;86:187-195. Epub 2017 Sep 18.

Department of Medical Psychology, Neuroscience Campus Amsterdam, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands; Neuroendocrinology, GIGA Neurosciences, University of Liège, Avenue Hippocrate, 15, 4000 Liège, Belgium.

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http://dx.doi.org/10.1016/j.psyneuen.2017.09.014DOI Listing
December 2017

Transient Elevated Serum Prolactin in Trans Women Is Caused by Cyproterone Acetate Treatment.

LGBT Health 2017 10 7;4(5):328-336. Epub 2017 Sep 7.

1 Department of Endocrinology, Ghent University Hospital , Ghent, Belgium .

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http://dx.doi.org/10.1089/lgbt.2016.0190DOI Listing
October 2017

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Am J Hum Genet 2017 Aug 27;101(2):227-238. Epub 2017 Jul 27.

Department of Human Genetics, McGill University, Montreal, QC H3A 1B1, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, QC H3T 1E2, Canada; Department of Twin Research and Genetic Epidemiology, King's College London, London WC2R 2LS, UK; Department of Medicine, McGill University, Montreal, QC H3G 1Y6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544392PMC
August 2017

Self-perception of voice in transgender persons during cross-sex hormone therapy.

Laryngoscope 2017 12 21;127(12):2796-2804. Epub 2017 Jul 21.

Centre for Sexology and Gender, Ghent, Belgium.

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http://doi.wiley.com/10.1002/lary.26716
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http://dx.doi.org/10.1002/lary.26716DOI Listing
December 2017

Is Hepatic Triglyceride Content Associated with Aortic Pulse Wave Velocity and Carotid Intima-Media Thickness? The Netherlands Epidemiology of Obesity Study.

Radiology 2017 10 29;285(1):73-82. Epub 2017 May 29.

From the Departments of Radiology (R.L.W., J.J.M.W., A.d.R., H.J.L.), Clinical Epidemiology (R.d.M., K.B.G., M.d.H., S.l.C., F.R.R.), Internal Medicine (K.B.G.), Medical Statistics and Bio-informatics (S.l.C.), Endocrinology (R.L.W., J.W.A.S.), and Cardiology (J.W.J.), Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, the Netherlands; Department of Internal Medicine, VU University Medical Center, Amsterdam, the Netherlands (M.d.H.); and Department of Internal Medicine, Radboud University Nijmegen Medical Center, Nijmegen, the Netherlands (J.W.A.S.).

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http://dx.doi.org/10.1148/radiol.2017160916DOI Listing
October 2017

Incidental findings in research: A focus group study about the perspective of the research participant.

J Magn Reson Imaging 2018 01 4;47(1):230-237. Epub 2017 May 4.

Department of Public Health and Primary Care, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.1002/jmri.25739DOI Listing
January 2018

Bone Mineral Density Increases in Trans Persons After 1 Year of Hormonal Treatment: A Multicenter Prospective Observational Study.

J Bone Miner Res 2017 Jun 2;32(6):1252-1260. Epub 2017 May 2.

Department of Internal Medicine and Center of Expertise on Gender Dysphoria, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1002/jbmr.3102DOI Listing
June 2017

Oestrogen and anti-androgen therapy for transgender women.

Lancet Diabetes Endocrinol 2017 04 2;5(4):291-300. Epub 2016 Dec 2.

Department of Endocrinology and Center of Expertise on Gender Dysphoria, VU University Medical Center, Amsterdam, Netherlands.

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http://dx.doi.org/10.1016/S2213-8587(16)30319-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5366074PMC
April 2017

Effect of pubertal suppression and cross-sex hormone therapy on bone turnover markers and bone mineral apparent density (BMAD) in transgender adolescents.

Bone 2017 02 11;95:11-19. Epub 2016 Nov 11.

Department of Clinical Chemistry, Endocrine Laboratory, VU University Medical Center, de Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2016.11.008DOI Listing
February 2017

Association between Hepatic Triglyceride Content and Left Ventricular Diastolic Function in a Population-based Cohort: The Netherlands Epidemiology of Obesity Study.

Radiology 2016 May 26;279(2):443-50. Epub 2016 Jan 26.

From the Departments of Radiology (R.L.W., A.d.R., H.J.L.), Endocrinology (R.L.W., J.W.A.S.), Clinical Epidemiology (R.d.M., M.d.H., S.l.C., F.R.R.), Medical Statistics and Bio-informatics (S.l.C.), Thrombosis and Haemostasis (F.R.R.), and Cardiology (J.W.J.), Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, the Netherlands.

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http://dx.doi.org/10.1148/radiol.2015150035DOI Listing
May 2016

Determination of human reference values for serum total 1,25-dihydroxyvitamin D using an extensively validated 2D ID-UPLC-MS/MS method.

J Steroid Biochem Mol Biol 2016 11 10;164:127-133. Epub 2015 Dec 10.

Department of Clinical Chemistry, Endocrine Laboratory, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jsbmb.2015.12.003DOI Listing
November 2016

Advantages and disadvantages of unstructured cardiovascular risk factor screening for follow-up in primary care.

Eur J Prev Cardiol 2016 07 24;23(11):1195-201. Epub 2015 Nov 24.

Department of Public Health and Primary Care, Leiden University Medical Centre, The Netherlands.

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http://dx.doi.org/10.1177/2047487315618794DOI Listing
July 2016

Overweight can be used as a tool to guide case-finding for cardiovascular risk assessment.

Fam Pract 2015 Dec 17;32(6):646-51. Epub 2015 Oct 17.

Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, Department of Primary and Community care, Radboud University Medical Center, Nijmegen, The Netherlands.

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https://academic.oup.com/fampra/article/32/6/646/2450443
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http://dx.doi.org/10.1093/fampra/cmv080DOI Listing
December 2015

Type 2 diabetes is associated with postprandial amino acid measures.

Arch Biochem Biophys 2016 Jan 10;589:138-44. Epub 2015 Aug 10.

Department of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1016/j.abb.2015.08.003DOI Listing
January 2016

Individual contributions of visceral fat and total body fat to subclinical atherosclerosis: The NEO study.

Atherosclerosis 2015 Aug 3;241(2):547-54. Epub 2015 Jun 3.

Department of Clinical Epidemiology, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00219150150134
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http://dx.doi.org/10.1016/j.atherosclerosis.2015.05.026DOI Listing
August 2015

Prevalence of cartilaginous tumours as an incidental finding on MRI of the knee.

Eur Radiol 2015 Dec 21;25(12):3480-7. Epub 2015 May 21.

Department of Radiology, C2-S, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00330-015-3764-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636526PMC
December 2015

Self-reported acne is not associated with prostate cancer.

Urol Oncol 2014 Oct 8;32(7):941-5. Epub 2014 Jul 8.

Department for Health Evidence, Radboud University Medical Center, Nijmegen, The Netherlands; Comprehensive Cancer Centre The Netherlands, Nijmegen, The Netherlands; Department of Urology, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2014.02.019DOI Listing
October 2014

Associations between thyroid function and mortality: the influence of age.

Eur J Endocrinol 2014 Aug 6;171(2):183-91. Epub 2014 May 6.

Division of EndocrinologyDepartment of MedicineDepartment for Health EvidenceDepartment of Laboratory MedicineDepartment of UrologyRadboud University Medical Centre, PO Box 9101, 6500 HB Nijmegen, The NetherlandsSection of EndocrinologyDepartment of Internal Medicine, VU University Medical Center, Amsterdam, The NetherlandsDivision of EndocrinologyDepartment of MedicineDepartment for Health EvidenceDepartment of Laboratory MedicineDepartment of UrologyRadboud University Medical Centre, PO Box 9101, 6500 HB Nijmegen, The NetherlandsSection of EndocrinologyDepartment of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1530/EJE-13-1070DOI Listing
August 2014

Plasma osteocalcin levels as a predictor of cardiovascular disease in older men and women: a population-based cohort study.

Eur J Endocrinol 2014 Aug 6;171(2):161-70. Epub 2014 May 6.

Division of EpidemiologyNorwegian Institute of Public Health, PO Box 4404 Nydalen, N-0403 Oslo, NorwayDepartment of Epidemiology and BiostatisticsEMGO Institute for Health and Care ResearchEndocrine SectionDepartment of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands.

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http://www.eje-online.org/content/early/2014/05/06/EJE-13-10
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http://www.eje-online.org/cgi/doi/10.1530/EJE-13-1044
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http://dx.doi.org/10.1530/EJE-13-1044DOI Listing
August 2014

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

Authors:
Marco Medici Eleonora Porcu Giorgio Pistis Alexander Teumer Suzanne J Brown Richard A Jensen Rajesh Rawal Greet L Roef Theo S Plantinga Sita H Vermeulen Jari Lahti Matthew J Simmonds Lise Lotte N Husemoen Rachel M Freathy Beverley M Shields Diana Pietzner Rebecca Nagy Linda Broer Layal Chaker Tim I M Korevaar Maria Grazia Plia Cinzia Sala Uwe Völker J Brent Richards Fred C Sweep Christian Gieger Tanguy Corre Eero Kajantie Betina Thuesen Youri E Taes W Edward Visser Andrew T Hattersley Jürgen Kratzsch Alexander Hamilton Wei Li Georg Homuth Monia Lobina Stefano Mariotti Nicole Soranzo Massimiliano Cocca Matthias Nauck Christin Spielhagen Alec Ross Alice Arnold Martijn van de Bunt Sandya Liyanarachchi Margit Heier Hans Jörgen Grabe Corrado Masciullo Tessel E Galesloot Ee M Lim Eva Reischl Peter J Leedman Sandra Lai Alessandro Delitala Alexandra P Bremner David I W Philips John P Beilby Antonella Mulas Matteo Vocale Goncalo Abecasis Tom Forsen Alan James Elisabeth Widen Jennie Hui Holger Prokisch Ernst E Rietzschel Aarno Palotie Peter Feddema Stephen J Fletcher Katharina Schramm Jerome I Rotter Alexander Kluttig Dörte Radke Michela Traglia Gabriela L Surdulescu Huiling He Jayne A Franklyn Daniel Tiller Bijay Vaidya Tim de Meyer Torben Jørgensen Johan G Eriksson Peter C O'Leary Eric Wichmann Ad R Hermus Bruce M Psaty Till Ittermann Albert Hofman Emanuele Bosi David Schlessinger Henri Wallaschofski Nicola Pirastu Yurii S Aulchenko Albert de la Chapelle Romana T Netea-Maier Stephen C L Gough Henriette Meyer Zu Schwabedissen Timothy M Frayling Jean-Marc Kaufman Allan Linneberg Katri Räikkönen Johannes W A Smit Lambertus A Kiemeney Fernando Rivadeneira André G Uitterlinden John P Walsh Christa Meisinger Martin den Heijer Theo J Visser Timothy D Spector Scott G Wilson Henry Völzke Anne Cappola Daniela Toniolo Serena Sanna Silvia Naitza Robin P Peeters

PLoS Genet 2014 Feb 27;10(2):e1004123. Epub 2014 Feb 27.

Department of Internal Medicine, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://repub.eur.nl/pub/65428/REPUB_65428_OA.pdf
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http://dx.plos.org/10.1371/journal.pgen.1004123
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http://dx.doi.org/10.1371/journal.pgen.1004123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937134PMC
February 2014

Prediction of vitamin D deficiency by simple patient characteristics.

Am J Clin Nutr 2014 May 19;99(5):1089-95. Epub 2014 Feb 19.

Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research (ES, MWH, MV, and NMvS), and the Departments of Internal Medicine and Endocrinology (RTdJ, MdH, and PL) and General Practice (TM), VU University Medical Center, Amsterdam, Netherlands; and the Department of Health Sciences, EMGO Institute for Health and Care Research, Faculty of Earth and Life Sciences, VU University Amsterdam, Amsterdam, Netherlands (MWH and MV).

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http://dx.doi.org/10.3945/ajcn.113.076430DOI Listing
May 2014

Body fat, especially visceral fat, is associated with electrocardiographic measures of sympathetic activation.

Obesity (Silver Spring) 2014 Jun 18;22(6):1553-9. Epub 2014 Feb 18.

Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, the Netherlands.

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http://dx.doi.org/10.1002/oby.20709DOI Listing
June 2014

Circulating uncarboxylated matrix Gla protein, a marker of vitamin K status, as a risk factor of cardiovascular disease.

Maturitas 2014 Feb 24;77(2):137-41. Epub 2013 Oct 24.

Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Centre, Amsterdam, The Netherlands; Department of Internal Medicine and Endocrinology, VU University Medical Centre, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.maturitas.2013.10.008DOI Listing
February 2014

[Homocysteine levels: measure or not?].

Ned Tijdschr Geneeskd 2013 ;157(44):A6265

VU Medisch Centrum, Amsterdam.

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June 2014

Combining risk markers improves cardiovascular risk prediction in women.

Clin Sci (Lond) 2014 Jan;126(2):139-46

*Department of General Internal Medicine, Division of Vascular Medicine, Radboud University Nijmegen Medical Centre, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1042/CS20130178DOI Listing
January 2014

[Chronic bone pain due to raised FGF23 production? The importance of determining phosphate levels].

Ned Tijdschr Geneeskd 2013 ;157(28):A5908

VUmc, Afd. Interne Geneeskunde, Amsterdam, the Netherlands.

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September 2013

Atherosclerosis decreases the impact of neuroticism in late-life depression: hypothesis of vascular apathy.

Am J Geriatr Psychiatry 2014 Aug 12;22(8):801-10. Epub 2013 Jun 12.

University Center of Psychiatry, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jagp.2013.01.001DOI Listing
August 2014

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.

Authors:
Joshua C Randall Thomas W Winkler Zoltán Kutalik Sonja I Berndt Anne U Jackson Keri L Monda Tuomas O Kilpeläinen Tõnu Esko Reedik Mägi Shengxu Li Tsegaselassie Workalemahu Mary F Feitosa Damien C Croteau-Chonka Felix R Day Tove Fall Teresa Ferreira Stefan Gustafsson Adam E Locke Iain Mathieson Andre Scherag Sailaja Vedantam Andrew R Wood Liming Liang Valgerdur Steinthorsdottir Gudmar Thorleifsson Emmanouil T Dermitzakis Antigone S Dimas Fredrik Karpe Josine L Min George Nicholson Deborah J Clegg Thomas Person Jon P Krohn Sabrina Bauer Christa Buechler Kristina Eisinger Amélie Bonnefond Philippe Froguel Jouke-Jan Hottenga Inga Prokopenko Lindsay L Waite Tamara B Harris Albert Vernon Smith Alan R Shuldiner Wendy L McArdle Mark J Caulfield Patricia B Munroe Henrik Grönberg Yii-Der Ida Chen Guo Li Jacques S Beckmann Toby Johnson Unnur Thorsteinsdottir Maris Teder-Laving Kay-Tee Khaw Nicholas J Wareham Jing Hua Zhao Najaf Amin Ben A Oostra Aldi T Kraja Michael A Province L Adrienne Cupples Nancy L Heard-Costa Jaakko Kaprio Samuli Ripatti Ida Surakka Francis S Collins Jouko Saramies Jaakko Tuomilehto Antti Jula Veikko Salomaa Jeanette Erdmann Christian Hengstenberg Christina Loley Heribert Schunkert Claudia Lamina H Erich Wichmann Eva Albrecht Christian Gieger Andrew A Hicks Asa Johansson Peter P Pramstaller Sekar Kathiresan Elizabeth K Speliotes Brenda Penninx Anna-Liisa Hartikainen Marjo-Riitta Jarvelin Ulf Gyllensten Dorret I Boomsma Harry Campbell James F Wilson Stephen J Chanock Martin Farrall Anuj Goel Carolina Medina-Gomez Fernando Rivadeneira Karol Estrada André G Uitterlinden Albert Hofman M Carola Zillikens Martin den Heijer Lambertus A Kiemeney Andrea Maschio Per Hall Jonathan Tyrer Alexander Teumer Henry Völzke Peter Kovacs Anke Tönjes Massimo Mangino Tim D Spector Caroline Hayward Igor Rudan Alistair S Hall Nilesh J Samani Antony Paul Attwood Jennifer G Sambrook Joseph Hung Lyle J Palmer Marja-Liisa Lokki Juha Sinisalo Gabrielle Boucher Heikki Huikuri Mattias Lorentzon Claes Ohlsson Niina Eklund Johan G Eriksson Cristina Barlassina Carlo Rivolta Ilja M Nolte Harold Snieder Melanie M Van der Klauw Jana V Van Vliet-Ostaptchouk Pablo V Gejman Jianxin Shi Kevin B Jacobs Zhaoming Wang Stephan J L Bakker Irene Mateo Leach Gerjan Navis Pim van der Harst Nicholas G Martin Sarah E Medland Grant W Montgomery Jian Yang Daniel I Chasman Paul M Ridker Lynda M Rose Terho Lehtimäki Olli Raitakari Devin Absher Carlos Iribarren Hanneke Basart Kees G Hovingh Elina Hyppönen Chris Power Denise Anderson John P Beilby Jennie Hui Jennifer Jolley Hendrik Sager Stefan R Bornstein Peter E H Schwarz Kati Kristiansson Markus Perola Jaana Lindström Amy J Swift Matti Uusitupa Mustafa Atalay Timo A Lakka Rainer Rauramaa Jennifer L Bolton Gerry Fowkes Ross M Fraser Jackie F Price Krista Fischer Kaarel Krjutå Kov Andres Metspalu Evelin Mihailov Claudia Langenberg Jian'an Luan Ken K Ong Peter S Chines Sirkka M Keinanen-Kiukaanniemi Timo E Saaristo Sarah Edkins Paul W Franks Göran Hallmans Dmitry Shungin Andrew David Morris Colin N A Palmer Raimund Erbel Susanne Moebus Markus M Nöthen Sonali Pechlivanis Kristian Hveem Narisu Narisu Anders Hamsten Steve E Humphries Rona J Strawbridge Elena Tremoli Harald Grallert Barbara Thorand Thomas Illig Wolfgang Koenig Martina Müller-Nurasyid Annette Peters Bernhard O Boehm Marcus E Kleber Winfried März Bernhard R Winkelmann Johanna Kuusisto Markku Laakso Dominique Arveiler Giancarlo Cesana Kari Kuulasmaa Jarmo Virtamo John W G Yarnell Diana Kuh Andrew Wong Lars Lind Ulf de Faire Bruna Gigante Patrik K E Magnusson Nancy L Pedersen George Dedoussis Maria Dimitriou Genovefa Kolovou Stavroula Kanoni Kathleen Stirrups Lori L Bonnycastle Inger Njølstad Tom Wilsgaard Andrea Ganna Emil Rehnberg Aroon Hingorani Mika Kivimaki Meena Kumari Themistocles L Assimes Inês Barroso Michael Boehnke Ingrid B Borecki Panos Deloukas Caroline S Fox Timothy Frayling Leif C Groop Talin Haritunians David Hunter Erik Ingelsson Robert Kaplan Karen L Mohlke Jeffrey R O'Connell David Schlessinger David P Strachan Kari Stefansson Cornelia M van Duijn Gonçalo R Abecasis Mark I McCarthy Joel N Hirschhorn Lu Qi Ruth J F Loos Cecilia M Lindgren Kari E North Iris M Heid

PLoS Genet 2013 Jun 6;9(6):e1003500. Epub 2013 Jun 6.

Wellcome Trust Sanger Institute, Hinxton, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1003500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674993PMC
June 2013

[Imputation of missing data].

Ned Tijdschr Geneeskd 2013 ;157(18):A5539

LUMC, afd. Klinische Epidemiologie, Leiden, the Netherlands.

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July 2013