Martin Widschwendter

Martin Widschwendter

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Martin Widschwendter

Martin Widschwendter

Publications by authors named "Martin Widschwendter"

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Association between the cervicovaginal microbiome, BRCA1 mutation status, and risk of ovarian cancer: a case-control study.

Lancet Oncol 2019 Aug 9;20(8):1171-1182. Epub 2019 Jul 9.

Department of Women's Cancer, EGA Institute for Women's Health, Faculty of Population Health Sciences, University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(19)30340-7DOI Listing
August 2019

A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases.

Mod Pathol 2019 Jun 25. Epub 2019 Jun 25.

Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, AB, Canada.

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http://dx.doi.org/10.1038/s41379-019-0302-0DOI Listing
June 2019

Accounting for differential variability in detecting differentially methylated regions.

Brief Bioinform 2019 01;20(1):47-57

Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.1093/bib/bbx097DOI Listing
January 2019

Mechanism of cytokinesis failure in ovarian cystadenomas with defective BRCA1 and P53 pathways.

Int J Cancer 2018 12 3;143(11):2932-2942. Epub 2018 Oct 3.

Department of Pathology, USC/Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1002/ijc.31659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235723PMC
December 2018

Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study.

Authors:
Peter F Rambau Robert A Vierkant Maria P Intermaggio Linda E Kelemen Marc T Goodman Esther Herpel Paul D Pharoah Stefan Kommoss Mercedes Jimenez-Linan Beth Y Karlan Aleksandra Gentry-Maharaj Usha Menon Susanna Hernando Polo Francisco J Candido Dos Reis Jennifer Anne Doherty Simon A Gayther Raghwa Sharma Melissa C Larson Paul R Harnett Emma Hatfield Jurandyr M de Andrade Gregg S Nelson Helen Steed Joellen M Schildkraut Micheal E Carney Estrid Høgdall Alice S Whittemore Martin Widschwendter Catherine J Kennedy Frances Wang Qin Wang Chen Wang Sebastian M Armasu Frances Daley Penny Coulson Micheal E Jones Micheal S Anglesio Christine Chow Anna de Fazio Montserrat García-Closas Sara Y Brucker Cezary Cybulski Holly R Harris Andreas D Hartkopf Tomasz Huzarski Allan Jensen Jan Lubiński Oleg Oszurek Javier Benitez Fady Mina Annette Staebler Florin Andrei Taran Jana Pasternak Aline Talhouk Mary Anne Rossing Joy Hendley Robert P Edwards Sian Fereday Francesmary Modugno Roberta B Ness Weiva Sieh Mona A El-Bahrawy Stacey J Winham Jenny Lester Susanne K Kjaer Jacek Gronwald Peter Sinn Peter A Fasching Jenny Chang-Claude Kirsten B Moysich David D Bowtell Brenda Y Hernandez Hugh Luk Sabine Behrens Mitul Shah Audrey Jung Prafull Ghatage Jennifer Alsop Kathryn Alsop Jesús García-Donas Pamela J Thompson Anthony J Swerdlow Chloe Karpinskyj Alicia Cazorla-Jiménez María J García Susha Deen Lynne R Wilkens José Palacios Andrew Berchuck Jennifer M Koziak James D Brenton Linda S Cook Ellen L Goode David G Huntsman Susan J Ramus Martin Köbel

J Pathol Clin Res 2018 10 21;4(4):250-261. Epub 2018 Sep 21.

Department of Pathology and Laboratory Medicine, University of Calgary, Foothills Medical Center, Calgary, AB, Canada.

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http://dx.doi.org/10.1002/cjp2.109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174617PMC
October 2018

A novel cell-type deconvolution algorithm reveals substantial contamination by immune cells in saliva, buccal and cervix.

Epigenomics 2018 07 25;10(7):925-940. Epub 2018 Apr 25.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, 320 Yue Yang Road, Shanghai 200031, PR China.

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https://www.futuremedicine.com/doi/10.2217/epi-2018-0037
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http://dx.doi.org/10.2217/epi-2018-0037DOI Listing
July 2018

Prediction models for endometrial cancer for the general population or symptomatic women: A systematic review.

Crit Rev Oncol Hematol 2018 Jun 31;126:92-99. Epub 2018 Mar 31.

Department of Public Health, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.critrevonc.2018.03.023DOI Listing
June 2018

DNA Methylation Patterns in Normal Tissue Correlate more Strongly with Breast Cancer Status than Copy-Number Variants.

EBioMedicine 2018 May 4;31:243-252. Epub 2018 May 4.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute of Nutrition and Health, Shanghai Institute for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 320 Yue Yang Road, Shanghai 200031, China; Department of Women's Cancer, University College London, 74 Huntley Street, London WC1E 6AU, United Kingdom; UCL Cancer Institute, Paul O'Gorman Building, University College London, 72 Huntley Street, London WC1E 6BT, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.04.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013931PMC
May 2018

Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.

Authors:
Ellen L Goode Matthew S Block Kimberly R Kalli Robert A Vierkant Wenqian Chen Zachary C Fogarty Aleksandra Gentry-Maharaj Aleksandra Tołoczko Alexander Hein Aliecia L Bouligny Allan Jensen Ana Osorio Andreas Hartkopf Andy Ryan Anita Chudecka-Głaz Anthony M Magliocco Arndt Hartmann Audrey Y Jung Bo Gao Brenda Y Hernandez Brooke L Fridley Bryan M McCauley Catherine J Kennedy Chen Wang Chloe Karpinskyj Christiani B de Sousa Daniel G Tiezzi David L Wachter Esther Herpel Florin Andrei Taran Francesmary Modugno Gregg Nelson Jan Lubiński Janusz Menkiszak Jennifer Alsop Jenny Lester Jesús García-Donas Jill Nation Jillian Hung José Palacios Joseph H Rothstein Joseph L Kelley Jurandyr M de Andrade Luis Robles-Díaz Maria P Intermaggio Martin Widschwendter Matthias W Beckmann Matthias Ruebner Mercedes Jimenez-Linan Naveena Singh Oleg Oszurek Paul R Harnett Peter F Rambau Peter Sinn Philipp Wagner Prafull Ghatage Raghwa Sharma Robert P Edwards Roberta B Ness Sandra Orsulic Sara Y Brucker Sharon E Johnatty Teri A Longacre Eilber Ursula Valerie McGuire Weiva Sieh Yanina Natanzon Zheng Li Alice S Whittemore deFazio Anna Annette Staebler Beth Y Karlan Blake Gilks David D Bowtell Estrid Høgdall Francisco J Candido dos Reis Helen Steed Ian G Campbell Jacek Gronwald Javier Benítez Jennifer M Koziak Jenny Chang-Claude Kirsten B Moysich Linda E Kelemen Linda S Cook Marc T Goodman María José García Peter A Fasching Stefan Kommoss Suha Deen Susanne K Kjaer Usha Menon James D Brenton Paul DP Pharoah Georgia Chenevix-Trench David G Huntsman Stacey J Winham Martin Köbel Susan J Ramus

JAMA Oncol 2017 12;3(12):e173290

School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia

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http://dx.doi.org/10.1001/jamaoncol.2017.3290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744673PMC
December 2017

Systems-epigenomics inference of transcription factor activity implicates aryl-hydrocarbon-receptor inactivation as a key event in lung cancer development.

Genome Biol 2017 Dec 20;18(1):236. Epub 2017 Dec 20.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, 320 Yue Yang Road, Shanghai, 200031, China.

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http://dx.doi.org/10.1186/s13059-017-1366-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738803PMC
December 2017

Testing breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples.

Br J Cancer 2017 Feb 12;116(4):501-508. Epub 2017 Jan 12.

Department of Women's Cancer, Institute for Women's Health, University College London, London, W1T 7DN, UK.

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http://dx.doi.org/10.1038/bjc.2016.433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318971PMC
February 2017

The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation.

Nucleic Acids Res 2016 12 14;44(22):10631-10643. Epub 2016 Sep 14.

Helmholtz-Institute for Biomedical Engineering, Stem Cell Biology and Cellular Engineering, RWTH University Medical School, Aachen 52074, Germany

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http://dx.doi.org/10.1093/nar/gkw802DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159544PMC
December 2016

Correlation of an epigenetic mitotic clock with cancer risk.

Genome Biol 2016 10 3;17(1):205. Epub 2016 Oct 3.

CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, 320 Yue Yang Road, Shanghai, 200031, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046977PMC
http://dx.doi.org/10.1186/s13059-016-1064-3DOI Listing
October 2016

Menopause accelerates biological aging.

Proc Natl Acad Sci U S A 2016 08 25;113(33):9327-32. Epub 2016 Jul 25.

Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095; Department of Biostatistics, Fielding School of Public Health, University of California, Los Angeles, CA 90095

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http://dx.doi.org/10.1073/pnas.1604558113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995944PMC
August 2016

The multi-omic landscape of transcription factor inactivation in cancer.

Genome Med 2016 08 25;8(1):89. Epub 2016 Aug 25.

Department of Women's Cancer, University College London, 74 Huntley Street, London, WC1E 6BT, UK.

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http://dx.doi.org/10.1186/s13073-016-0342-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997779PMC
August 2016

Erratum to: The integrative epigenomic-transcriptomic landscape of ER positive breast cancer.

Clin Epigenetics 2016 1;8:63. Epub 2016 Jun 1.

CAS Key Lab for Computational Biology, CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences, Shanghai Institute for Biological Sciences, 320 Yue Yang Road, Shanghai, 200031 China ; Department of Women's Cancer, University College London, 74 Huntley Street, London, WC1E 6BT UK ; Statistical Genomics Group, Paul O'Gorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6BT UK.

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http://dx.doi.org/10.1186/s13148-016-0231-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890493PMC
July 2016

DNA Methylation Signatures in Vaginal Fluid Samples for Detection of Cervical and Endometrial Cancer.

Int J Gynecol Cancer 2016 Jun 2. Epub 2016 Jun 2.

*Department of Women's Cancer, Elizabeth Garrett Anderson Institute for Women's Health, University College London, London, United Kingdom; †CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai; and ‡University of Chinese Academy of Sciences, Beijing, China; and §UCL Cancer Institute, University College London, London, United Kingdom.

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http://dx.doi.org/10.1097/IGC.0000000000000739DOI Listing
June 2016

Epigenetic drift, epigenetic clocks and cancer risk.

Epigenomics 2016 05 22;8(5):705-19. Epub 2016 Apr 22.

CAS Key Lab of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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https://www.futuremedicine.com/doi/10.2217/epi-2015-0017
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http://dx.doi.org/10.2217/epi-2015-0017DOI Listing
May 2016

Stochastic epigenetic outliers can define field defects in cancer.

BMC Bioinformatics 2016 Apr 22;17:178. Epub 2016 Apr 22.

Department of Women's Cancer, University College London, 74 Huntley Street, London, WC1E 6AU, UK.

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http://dx.doi.org/10.1186/s12859-016-1056-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840974PMC
April 2016

PPM1D Mosaic Truncating Variants in Ovarian Cancer Cases May Be Treatment-Related Somatic Mutations.

J Natl Cancer Inst 2016 Mar 27;108(3). Epub 2016 Jan 27.

Affiliations of authors:CR-UK Department of Oncology, University of Cambridge, Strangeways Research Laboratory , Cambridge, UK (PDPP, HS, ED, PH, CB); Department of Preventive Medicine, Keck School of Medicine , USC/NorrisComprehensive Cancer Center, University of Southern California , CA (MPI, SAG, SJR); Peter MacCallum Cancer Centre, East Melbourne , Victoria , Australia (KA, AOCSG, DDB); Westmead Millennium Institute, Westmead Hospital , Sydney , Australia (AOCSG); The QIMR Berghofer Medical Research Institute , Brisbane , Australia (AOCSG); Gynaecology Research Unit, Hannover Medical School , Hannover , Germany (NB, TD); Radiation Oncology Research Unit, Hannover Medical School , Hannover , Germany (NB); Mother and Child Hospital , Minsk , Belarus (NB); Department of Health Science Research, Division of Epidemiology, Mayo Clinic , Rochester, MN (MSC, JMC, ELG); Department of Biostatistics, University of Kansas Medical Center , KS (BLF); Gynaecological Cancer Research Centre, Women's Cancer, Institute for Women's Health, University College London , London, UK (AGM, MW, UM); Clinics of Obstetrics and Gynaecology, Hannover Medical School , Hannover , Germany (PH); Department of Gynecological Oncology, Roswell Park Cancer Institute , Buffalo, NY (SL, SP, KO); Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center , Los Angeles, CA (JL, BYK); Department of Health Research and Policy - Epidemiology, Stanford University School of Medicine , Stanford, CA (VM, WS, ASW); Department of Cancer Prevention and Control, Roswell Park Cancer Institute , Buffalo, NY (KBM, LSC); Department of Obstetrics and Gynecology, Duke University Medical Center , Durham, NC (OCAC); Department of Biochemistry and Molecular Biology, University of Melbourne , Melbourne, Victoria , Australia (DDB); Sir Peter MacCallum Department of Oncology, University of Melbourne , Melbourne, Victoria , Australia (DDB); Ovarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London , London, UK (DDB).

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https://academic.oup.com/jnci/article-lookup/doi/10.1093/jnc
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http://dx.doi.org/10.1093/jnci/djv347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072371PMC
March 2016

Integration of genetic and epigenetic markers for risk stratification: opportunities and challenges.

Per Med 2016 Mar;13(2):93-95

University College London, Department of Women's Cancer, London, UK.

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http://dx.doi.org/10.2217/pme.15.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820043PMC
March 2016

DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer.

Nat Commun 2016 Jan 29;7:10478. Epub 2016 Jan 29.

Department of Women's Cancer, University College London, Medical School Building, Room 340, 74 Huntley Street, London WC1E 6AU, UK.

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http://dx.doi.org/10.1038/ncomms10478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740178PMC
January 2016

The integrative epigenomic-transcriptomic landscape of ER positive breast cancer.

Clin Epigenetics 2015 9;7:126. Epub 2015 Dec 9.

CAS Key Lab for Computational Biology, CAS-MPG Partner Institute for Computational Biology, Chinese Academy of Sciences, Shanghai Institute for Biological Sciences, 320 Yue Yang Road, 200031 Shanghai, China ; Department of Women's Cancer, University College London, 74 Huntley Street, London, WC1E 6BT UK ; Statistical Genomics Group, Paul O'Gorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, London, WC1E 6BT UK.

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http://dx.doi.org/10.1186/s13148-015-0159-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673726PMC
December 2015

A Mouse Model That Reproduces the Developmental Pathways and Site Specificity of the Cancers Associated With the Human BRCA1 Mutation Carrier State.

EBioMedicine 2015 Oct 9;2(10):1318-30. Epub 2015 Sep 9.

Department of Pathology, Keck School of Medicine of University of Southern California, Los Angeles, CA 90089, United States.

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http://dx.doi.org/10.1016/j.ebiom.2015.08.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634618PMC
October 2015

An integrative pan-cancer-wide analysis of epigenetic enzymes reveals universal patterns of epigenomic deregulation in cancer.

Genome Biol 2015 Jul 14;16:140. Epub 2015 Jul 14.

Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, 320 Yue Yang Road, Shanghai, 200031, China.

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http://dx.doi.org/10.1186/s13059-015-0699-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501092PMC
July 2015

Risk Algorithm Using Serial Biomarker Measurements Doubles the Number of Screen-Detected Cancers Compared With a Single-Threshold Rule in the United Kingdom Collaborative Trial of Ovarian Cancer Screening.

J Clin Oncol 2015 Jun 11;33(18):2062-71. Epub 2015 May 11.

Usha Menon, Andy Ryan, Jatinderpal Kalsi, Aleksandra Gentry-Maharaj, Mariam Habib, Sophia Apostolidou, Matthew Burnell, Susan Davies, Richard Gunu, Martin Widschwendter, Elizabeth Benjamin, Mahesh Parmar, and Ian Jacobs, University College London; Anne Dawnay and Tim Mould, University College London Hospital; Naveena Singh, Barts and the London School of Medicine and Dentistry; David Oram and Karina Reynolds, St Bartholomew's Hospital; Alistair McGuire, London School of Economics; Stuart Campbell, Create Health Clinic; Aarti Sharma, University Hospital of Wales; Nazar N. Amso, Cardiff University, Cardiff; Keith Godfrey, Queen Elizabeth Hospital, Gateshead; Alberto Lopes, Royal Cornwall Hospital, Truro; Jonathan Herod, Liverpool Women's Hospital, Liverpool; Karin Williamson, Nottingham City Hospital, Nottingham; Mourad W. Seif, St Mary's Hospital, Manchester; Howard Jenkins and Ian Scott, Royal Derby Hospital, Derby; Robert Woolas, Queen Alexandra Hospital, Portsmouth; John B. Murdoch, St Michael's Hospital, Bristol; Stephen Dobbs, Belfast City Hospital, Belfast; Simon Leeson, Llandudno Hospital, Ysbyty Gwynedd; Derek Cruickshank, James Cook University Hospital, Middlesbrough; Lesley Fallowfield, University of Sussex, Falmer, United Kingdom; Steven J. Skates, Massachusetts General Hospital and Harvard Medical School, Boston, MA; and Ian Jacobs, UNSW Australia, Sydney, NSW, Australia.

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http://ascopubs.org/doi/10.1200/JCO.2014.59.4945
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http://dx.doi.org/10.1200/JCO.2014.59.4945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463475PMC
June 2015

A systems-level integrative framework for genome-wide DNA methylation and gene expression data identifies differential gene expression modules under epigenetic control.

Bioinformatics 2014 Aug 2;30(16):2360-6. Epub 2014 May 2.

Computational Systems Genomics, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China, Department of Women's Cancer, UCL Elizabeth Garrett Anderson Institute for Women's Health and Statistical Genomics Group, Paul O'Gorman Building, UCL Cancer Institute, University College London, London WC1E 6BT, UKComputational Systems Genomics, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China, Department of Women's Cancer, UCL Elizabeth Garrett Anderson Institute for Women's Health and Statistical Genomics Group, Paul O'Gorman Building, UCL Cancer Institute, University College London, London WC1E 6BT, UK.

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http://dx.doi.org/10.1093/bioinformatics/btu316DOI Listing
August 2014

The dynamics of DNA methylation covariation patterns in carcinogenesis.

PLoS Comput Biol 2014 Jul 10;10(7):e1003709. Epub 2014 Jul 10.

Key Laboratory of Systems Biology, SIBS-Nordisk Translational Research Centre for PreDiabetes, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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http://dx.doi.org/10.1371/journal.pcbi.1003709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091688PMC
July 2014

A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival.

Genome Med 2014 27;6(6):47. Epub 2014 Jun 27.

Department of Women's Cancer, UCL Elizabeth Garrett Anderson Institute for Women's Health, University College London, 74 Huntley Street, London WC1E 6 AU, UK.

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http://dx.doi.org/10.1186/gm567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4110671PMC
July 2014

PP2A-B55β antagonizes cyclin E1 proteolysis and promotes its dysregulation in cancer.

Cancer Res 2014 Apr 7;74(7):2006-14. Epub 2014 Feb 7.

Authors' Affiliations: Tumor Initiation and Maintenance Program, Cancer Center, Sanford-Burnham Medical Research Institute, La Jolla; Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California; and Department of Gynaecological Oncology, University College London, London, United Kingdom.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-1263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064712PMC
April 2014

A prospective validation of the IOTA logistic regression models (LR1 and LR2) in comparison to subjective pattern recognition for the diagnosis of ovarian cancer.

Int J Gynecol Cancer 2013 Nov;23(9):1583-9

*Gynaecological Diagnostic Outpatient Treatment Unit, University College Hospital; †Department of Statistical Science, University College London; and ‡Department of Women's Cancer, University College London, Elizabeth Garrett Anderson, Institute for Women's Health, London, United Kingdom.

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http://dx.doi.org/10.1097/IGC.0b013e3182a6171aDOI Listing
November 2013

The sex hormone system in carriers of BRCA1/2 mutations: a case-control study.

Lancet Oncol 2013 Nov 17;14(12):1226-32. Epub 2013 Oct 17.

Department of Women's Cancer, UCL EGA Institute for Women's Health, University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(13)70448-0DOI Listing
November 2013

Cellular network entropy as the energy potential in Waddington's differentiation landscape.

Sci Rep 2013 Oct 24;3:3039. Epub 2013 Oct 24.

1] Statistical Cancer Genomics, Paul O'Gorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, United Kingdom [2] Centre for Mathematics and Physics in the Life Sciences and Experimental Biology, University College London, London WC1E6BT United Kingdom.

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http://dx.doi.org/10.1038/srep03039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3807110PMC
October 2013

Distinctive topology of age-associated epigenetic drift in the human interactome.

Proc Natl Acad Sci U S A 2013 Aug 12;110(35):14138-43. Epub 2013 Aug 12.

Statistical Cancer Genomics, University College London Cancer Institute, University College London, London WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1307242110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761591PMC
August 2013

GALR1 methylation in vaginal swabs is highly accurate in identifying women with endometrial cancer.

Int J Gynecol Cancer 2013 Jul;23(6):1050-5

Department of Women's Cancer, University College London Elizabeth Garrett Anderson Institute for Women's Health, University College London, United Kingdom.

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http://dx.doi.org/10.1097/IGC.0b013e3182959103DOI Listing
July 2013

Epigenetics makes its mark on women-specific cancers--an opportunity to redefine oncological approaches?

Gynecol Oncol 2013 Jan 1;128(1):134-143. Epub 2012 Oct 1.

Statistical Genomics Group, Paul O'Gorman Building, UCL Cancer Institute, University College London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S00908258120078
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http://dx.doi.org/10.1016/j.ygyno.2012.09.027DOI Listing
January 2013

Noninvasive nutritional management of ovarian cancer patients: beyond intestinal obstruction.

Int J Gynecol Cancer 2012 Jul;22(6):1089-95

Department of Women's Cancer, EGA Institute for Women's Health, University College London, London, United Kingdom.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/IGC.0b013e318256e4d3DOI Listing
July 2012

Differential variability improves the identification of cancer risk markers in DNA methylation studies profiling precursor cancer lesions.

Bioinformatics 2012 Jun 6;28(11):1487-94. Epub 2012 Apr 6.

Statistical Genomics Group, Paul O'Gorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, London, UK.

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http://dx.doi.org/10.1093/bioinformatics/bts170DOI Listing
June 2012

A comparison of feature selection and classification methods in DNA methylation studies using the Illumina Infinium platform.

BMC Bioinformatics 2012 Apr 24;13:59. Epub 2012 Apr 24.

Statistical Genomics Group, Paul O'Gorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK.

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http://dx.doi.org/10.1186/1471-2105-13-59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364843PMC
April 2012

Epigenetic variability in cells of normal cytology is associated with the risk of future morphological transformation.

Genome Med 2012 Mar 27;4(3):24. Epub 2012 Mar 27.

Statistical Genomics Group, Paul O'Gorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK.

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http://dx.doi.org/10.1186/gm323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446274PMC
March 2012

Fooled by the film: delayed diagnosis of incarcerated small-bowel hernia after laparoscopic surgery for endometrial cancer.

Int J Gynecol Cancer 2012 Feb;22(2):337-9

Barts Cancer Institute, A Cancer Research UK Centre of Excellence, Barts and the London School of Medicine and Dentistry, London, England.

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http://dx.doi.org/10.1097/IGC.0b013e31823c244bDOI Listing
February 2012

Underlying mechanisms of ovarian cancer risk reduction after tubal ligation.

Acta Obstet Gynecol Scand 2011 Jun 15;90(6):559-63. Epub 2011 Apr 15.

Oncogynecological Center, Department of Obstetrics and Gynecology, General Teaching Hospital, First Medical School, Charles University, Prague, Czech Republic.

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http://dx.doi.org/10.1111/j.1600-0412.2011.01114.xDOI Listing
June 2011

Independent surrogate variable analysis to deconvolve confounding factors in large-scale microarray profiling studies.

Bioinformatics 2011 Jun 6;27(11):1496-505. Epub 2011 Apr 6.

Statistical Genomics Group, Paul O'Gorman Building, UCL Cancer Institute, London WC1E 6BT, UK.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btr171DOI Listing
June 2011

Genome-wide DNA methylation analysis of archival formalin-fixed paraffin-embedded tissue using the Illumina Infinium HumanMethylation27 BeadChip.

Methods 2010 Nov 29;52(3):248-54. Epub 2010 Apr 29.

Medical Genomics Group, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK.

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http://dx.doi.org/10.1016/j.ymeth.2010.04.012DOI Listing
November 2010

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

Authors:
Ellen L Goode Georgia Chenevix-Trench Honglin Song Susan J Ramus Maria Notaridou Kate Lawrenson Martin Widschwendter Robert A Vierkant Melissa C Larson Susanne K Kjaer Michael J Birrer Andrew Berchuck Joellen Schildkraut Ian Tomlinson Lambertus A Kiemeney Linda S Cook Jacek Gronwald Montserrat Garcia-Closas Martin E Gore Ian Campbell Alice S Whittemore Rebecca Sutphen Catherine Phelan Hoda Anton-Culver Celeste Leigh Pearce Diether Lambrechts Mary Anne Rossing Jenny Chang-Claude Kirsten B Moysich Marc T Goodman Thilo Dörk Heli Nevanlinna Roberta B Ness Thorunn Rafnar Claus Hogdall Estrid Hogdall Brooke L Fridley Julie M Cunningham Weiva Sieh Valerie McGuire Andrew K Godwin Daniel W Cramer Dena Hernandez Douglas Levine Karen Lu Edwin S Iversen Rachel T Palmieri Richard Houlston Anne M van Altena Katja K H Aben Leon F A G Massuger Angela Brooks-Wilson Linda E Kelemen Nhu D Le Anna Jakubowska Jan Lubinski Krzysztof Medrek Anne Stafford Douglas F Easton Jonathan Tyrer Kelly L Bolton Patricia Harrington Diana Eccles Ann Chen Ashley N Molina Barbara N Davila Hector Arango Ya-Yu Tsai Zhihua Chen Harvey A Risch John McLaughlin Steven A Narod Argyrios Ziogas Wendy Brewster Aleksandra Gentry-Maharaj Usha Menon Anna H Wu Daniel O Stram Malcolm C Pike Jonathan Beesley Penelope M Webb Xiaoqing Chen Arif B Ekici Falk C Thiel Matthias W Beckmann Hannah Yang Nicolas Wentzensen Jolanta Lissowska Peter A Fasching Evelyn Despierre Frederic Amant Ignace Vergote Jennifer Doherty Rebecca Hein Shan Wang-Gohrke Galina Lurie Michael E Carney Pamela J Thompson Ingo Runnebaum Peter Hillemanns Matthias Dürst Natalia Antonenkova Natalia Bogdanova Arto Leminen Ralf Butzow Tuomas Heikkinen Kari Stefansson Patrick Sulem Sören Besenbacher Thomas A Sellers Simon A Gayther Paul D P Pharoah

Nat Genet 2010 Oct 19;42(10):874-9. Epub 2010 Sep 19.

Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1038/ng.668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020231PMC
October 2010

Development and validation of a method for profiling post-translational modification activities using protein microarrays.

PLoS One 2010 Jun 28;5(6):e11332. Epub 2010 Jun 28.

Signal Transduction Program, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893156PMC
June 2010

DNA methylation of polycomb group target genes in cores taken from breast cancer centre and periphery.

Breast Cancer Res Treat 2010 Apr 8;120(2):345-55. Epub 2009 Apr 8.

Department of Gynaecological Oncology, Institute for Women's Health, University College London, 1st Floor, Maple House, 149 Tottenham Court Road, London, W1T 7DN, UK.

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http://dx.doi.org/10.1007/s10549-009-0384-3DOI Listing
April 2010

Emerging promise of epigenetics and DNA methylation for the diagnosis and management of women's cancers.

Epigenomics 2010 Feb;2(1):9-38

Department of Gynecological Oncology, Institute for Women's Health, University College London, 149 Tottenham Court Road, London, UK.

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http://dx.doi.org/10.2217/epi.09.47DOI Listing
February 2010

DNA methylation analysis in liquid-based cytology for cervical cancer screening.

Int J Cancer 2009 Dec;125(12):2995-3002

Department of Gynecological Oncology, Institute for Women's Health, University College London, London WC1E 6DH, United Kingdom.

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http://dx.doi.org/10.1002/ijc.24745DOI Listing
December 2009

HOXA11 DNA methylation--a novel prognostic biomarker in ovarian cancer.

Int J Cancer 2008 Aug;123(3):725-9

Department of Gynecological Oncology, UCL EGA Institute for Women's Health, University College London, United Kingdom.

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http://dx.doi.org/10.1002/ijc.23563DOI Listing
August 2008

Epigenetic stem cell signature in cancer.

Nat Genet 2007 Feb 31;39(2):157-8. Epub 2006 Dec 31.

Department of Gynecological Oncology, Institute for Women's Health, University College London, London WC1E 6DH, UK.

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http://dx.doi.org/10.1038/ng1941DOI Listing
February 2007

Circulating methylated DNA: a new generation of tumor markers.

Clin Cancer Res 2006 Dec;12(24):7205-8

Department of Gynaecological Oncology, UCL Elizabeth Garrett Institute for Women's Health, University College London, London, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-2531DOI Listing
December 2006