Publications by authors named "Martin Traebert"

23Publications

Reprint of: Nonclinical species sensitivity to convulsions: An IQ DruSafe consortium working group initiative.

J Pharmacol Toxicol Methods 2020 Sep 30;105:106919. Epub 2020 Sep 30.

Boehringer Ingelheim Pharma GmbH & Co. KG, Development NCE NDS, Biberach an der Riß 88397, Germany.

View Article and Find Full Text PDF
September 2020

The roles of human induced pluripotent stem cell-derived cardiomyocytes in drug discovery: managing in vitro safety study expectations.

Expert Opin Drug Discov 2020 06 27;15(6):719-729. Epub 2020 Mar 27.

Novartis Institutes for Biomedical Research , Safety Pharmacology, Basel, Switzerland.

View Article and Find Full Text PDF
June 2020

Nonclinical species sensitivity to convulsions: An IQ DruSafe consortium working group initiative.

J Pharmacol Toxicol Methods 2020 May - Jun;103:106683. Epub 2020 Feb 24.

Boehringer Ingelheim Pharma GmbH & Co. KG, Development NCE NDS, 88397 Biberach an der Riß, Germany.

View Article and Find Full Text PDF
February 2020

Cross - site comparison of excitation-contraction coupling using impedance and field potential recordings in hiPSC cardiomyocytes.

J Pharmacol Toxicol Methods 2018 Sep - Oct;93:46-58. Epub 2018 Jun 22.

Nanion Technologies GmbH, Ganghoferstrasse 70A, 80339 Munich, Germany. Electronic address:

View Article and Find Full Text PDF
January 2019

Histone Deacetylase Inhibitors Prolong Cardiac Repolarization through Transcriptional Mechanisms.

Toxicol Sci 2016 09 2;153(1):39-54. Epub 2016 Jun 2.

Preclinical Safety, Novartis Institutes of Biomedical Research, One Health Plaza, East Hanover, NJ 07936-1080.

View Article and Find Full Text PDF
September 2016

Differentiating electrophysiological effects and cardiac safety of drugs based on the electrocardiogram: a blinded validation.

Heart Rhythm 2012 Oct 16;9(10):1706-15. Epub 2012 Jun 16.

Lankenau Institute for Medical Research and Main Line Health Heart Center, 100 Lancaster Ave., Wynnewood, PA 19096, USA.

View Article and Find Full Text PDF
October 2012

Antimalarial drugs: QT prolongation and cardiac arrhythmias.

Expert Opin Drug Saf 2005 May;4(3):421-31

Exploratory Development, Safety Profiling and Assessment, Novartis Pharma AG, MUT-2881.204, CH-4002 Basel, Switzerland.

View Article and Find Full Text PDF
May 2005

Inhibition of hERG K+ currents by antimalarial drugs in stably transfected HEK293 cells.

Eur J Pharmacol 2004 Jan;484(1):41-8

Preclinical Safety, Novartis Pharma AG, MUT-2881.205, CH-4002, Basel, Switzerland.

View Article and Find Full Text PDF
January 2004

Site-specific effects of ghrelin on the neuronal activity in the hypothalamic arcuate nucleus.

Neurosci Lett 2003 May;341(2):151-5

Institute of Veterinary Physiology, University of Zurich, Winterthurerstrasse 260, 8057, Zurich, Switzerland.

View Article and Find Full Text PDF
May 2003