Martin Sill

Martin Sill

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Martin Sill

Martin Sill

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High impact of miRNA-4521 on FOXM1 expression in medulloblastoma.

Cell Death Dis 2019 Sep 20;10(10):696. Epub 2019 Sep 20.

Department of Pediatrics and Adolescent Medicine, Molecular Neuro-Oncology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/s41419-019-1926-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754377PMC
September 2019

RF_Purify: a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression.

BMC Bioinformatics 2019 Aug 16;20(1):428. Epub 2019 Aug 16.

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1186/s12859-019-3014-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697926PMC
August 2019

Global DNA methylation reflects spatial heterogeneity and molecular evolution of lung adenocarcinomas.

Int J Cancer 2019 03 3;144(5):1061-1072. Epub 2018 Dec 3.

Division of Cancer Genome Research, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.31939DOI Listing
March 2019

Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre.

Acta Neuropathol Commun 2019 Feb 20;7(1):24. Epub 2019 Feb 20.

Division of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, Queen Square, London, WC1N 3BG, UK.

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https://actaneurocomms.biomedcentral.com/articles/10.1186/s4
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http://dx.doi.org/10.1186/s40478-019-0668-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381711PMC
February 2019

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance.

Cell Death Dis 2017 08 24;8(8):e3013. Epub 2017 Aug 24.

Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), INF 280, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1038/cddis.2017.398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596581PMC
August 2017

Radiogenomics of Glioblastoma: Machine Learning-based Classification of Molecular Characteristics by Using Multiparametric and Multiregional MR Imaging Features.

Radiology 2016 Dec 16;281(3):907-918. Epub 2016 Sep 16.

From the Department of Neuroradiology, University of Heidelberg Medical Center, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany (P.K., S.B., O.E., M.B.); German Cancer Research Center (DKFZ), Department of Radiology, Heidelberg, Germany (D.B., H.P.S., A.R.); Department of Neurology, Medical University Innsbruck, Austria (M.N.); Department of Neuropathology, University of Heidelberg Medical Center, Heidelberg, Germany (A.K., A.v.D., D.C.); German Cancer Consortium (DKTK), Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany (A.K., A.v.D., D.C.); Division of Biostatistics, DKFZ, Heidelberg, Germany (M.S.); Neurology Clinic, University of Heidelberg Medical Center, Heidelberg, Germany (M.N., S.B., A.W., W.W.); Department of Radiation Oncology, University of Heidelberg Medical Center, Heidelberg, Germany (J.D.); Clinical Cooperation Unit Radiation Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany (J.D.); Division of Neurosurgical Research, Department of Neurosurgery, University of Heidelberg Medical Center, Heidelberg, Germany (C.H.M.); Department of Neurosurgery, University of Heidelberg Medical Center, Heidelberg, Germany (A.U.); Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany (D.J., S.P.); German Cancer Consortium (DKTK) Core Center Heidelberg, Heidelberg, Germany (D.J., S.P.); Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany (S.P.); and German Cancer Consortium (DKTK), Clinical Cooperation Unit Neurooncology, DKFZ, Heidelberg, Germany (W.W.).

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http://dx.doi.org/10.1148/radiol.2016161382DOI Listing
December 2016

Protein Profiling Gastric Cancer and Neighboring Control Tissues Using High-Content Antibody Microarrays.

Microarrays (Basel) 2016 Jul 8;5(3). Epub 2016 Jul 8.

Division of Functional Genome Analysis, Deutsches Krebsforschungszentrum (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5040966PMC
http://dx.doi.org/10.3390/microarrays5030019DOI Listing
July 2016

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups.

Neuro Oncol 2016 06 28;18(6):790-6. Epub 2016 Jan 28.

Institute of Neuropathology, University Hospital Münster, Münster, Germany (C.T., V.R., A.J., W.P., M.H.); Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany (M.S.); Core Facility Genomics of the Medical Faculty Münster, Münster, Germany (A.W.); Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (S.H., U.K.); Department of Neuropathology, Institute for Pathology and Neuropathology, University of Tübingen, Tübingen, Germany (R.B.); Faculty of Medicine, Institute of Neuropathology, University of Duisburg-Essen, Essen, Germany (K.K.); Department of Neuropathology, Klinikum Bremen-Mitte, Bremen, Germany (M.B.); Institute of Neurology (Edinger Institute), Goethe University, Frankfurt, Germany (M.M.); Institute of Neuropathology, University of Bonn Medical Center, Bonn, Germany (T.P.); Department of Neuropathology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany (J.F.); Department of Neuropathology, Institute of Pathology, University of Würzburg, and Comprehensive Cancer Center Mainfranken (CCCM), Würzburg, Germany (C.M.M.); Department of Neuropathology, Sainte-Anne Hospital, Paris, France (P.V.); 2nd Department of Paediatrics, Semmelweis University, Budapest, Hungary (P.H.); Department of Hematopathology, Molecular Diagnostic Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (A.O.); Children's Brain Tumour Research Centre, School of Medicine, Queen's Medical Centre, University of Nottingham, Nottingham, UK (R.G.G.); Department of Pediatric Hematology Oncology and Blood and Marrow Transplantation, Cleveland Clinic Children's Hospital, Cleveland, Ohio (J.E.W.); Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany (A.K., A.v.D., D.C.); Clinical Cooperation Unit Neuropathology, German Research Center (DKFZ), Heidelberg, Germany (A.K., A.v.D., D.C.); German Cancer Consortium (DKTK), German Cancer Research Ce

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http://dx.doi.org/10.1093/neuonc/nov322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864264PMC
June 2016

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.

Authors:
Dominik Sturm Brent A Orr Umut H Toprak Volker Hovestadt David T W Jones David Capper Martin Sill Ivo Buchhalter Paul A Northcott Irina Leis Marina Ryzhova Christian Koelsche Elke Pfaff Sariah J Allen Gnanaprakash Balasubramanian Barbara C Worst Kristian W Pajtler Sebastian Brabetz Pascal D Johann Felix Sahm Jüri Reimand Alan Mackay Diana M Carvalho Marc Remke Joanna J Phillips Arie Perry Cynthia Cowdrey Rachid Drissi Maryam Fouladi Felice Giangaspero Maria Łastowska Wiesława Grajkowska Wolfram Scheurlen Torsten Pietsch Christian Hagel Johannes Gojo Daniela Lötsch Walter Berger Irene Slavc Christine Haberler Anne Jouvet Stefan Holm Silvia Hofer Marco Prinz Catherine Keohane Iris Fried Christian Mawrin David Scheie Bret C Mobley Matthew J Schniederjan Mariarita Santi Anna M Buccoliero Sonika Dahiya Christof M Kramm André O von Bueren Katja von Hoff Stefan Rutkowski Christel Herold-Mende Michael C Frühwald Till Milde Martin Hasselblatt Pieter Wesseling Jochen Rößler Ulrich Schüller Martin Ebinger Jens Schittenhelm Stephan Frank Rainer Grobholz Istvan Vajtai Volkmar Hans Reinhard Schneppenheim Karel Zitterbart V Peter Collins Eleonora Aronica Pascale Varlet Stephanie Puget Christelle Dufour Jacques Grill Dominique Figarella-Branger Marietta Wolter Martin U Schuhmann Tarek Shalaby Michael Grotzer Timothy van Meter Camelia-Maria Monoranu Jörg Felsberg Guido Reifenberger Matija Snuderl Lynn Ann Forrester Jan Koster Rogier Versteeg Richard Volckmann Peter van Sluis Stephan Wolf Tom Mikkelsen Amar Gajjar Kenneth Aldape Andrew S Moore Michael D Taylor Chris Jones Nada Jabado Matthias A Karajannis Roland Eils Matthias Schlesner Peter Lichter Andreas von Deimling Stefan M Pfister David W Ellison Andrey Korshunov Marcel Kool

Cell 2016 Feb;164(5):1060-1072

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.

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http://www.cell.com/cell/pdf/S0092-8674(16)00055-6.pdf
Web Search
http://www.cell.com/cms/attachment/2048488015/2058390163/mmc
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S009286741600055
Publisher Site
http://dx.doi.org/10.1016/j.cell.2016.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139621PMC
February 2016

Applying stability selection to consistently estimate sparse principal components in high-dimensional molecular data.

Bioinformatics 2015 Aug 10;31(16):2683-90. Epub 2015 Apr 10.

Division of Biostatistics, DKFZ, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/bioinformatics/btv197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528629PMC
August 2015

Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial.

Neuro Oncol 2014 Dec 15;16(12):1630-8. Epub 2014 Jul 15.

Department of Neurooncology (B.W., M.P., W.W.); Department of Neuropathology (D.C., A.v.D.); Department of Pediatric Oncology, Hematology, and Immunology, Heidelberg University Hospital (S.M.P.); Clinical Cooperation Units Neurooncology (B.W., W.W.), Neuropathology (D.C, A.v.D.); Neuroimmunology and Brain Tumor Immunology (M.P.); Division of Molecular Genetics (V.H.); Division of Biostatistics (M.S.); Division of Pediatric Neurooncology (S.M.P., D.T.W.J.), German Cancer Research Center (DKFZ), Heidelberg, Germany (O.D.W.) and German Cancer Consortium (DKTK); Department for Neuropathology, Institute of Pathology, Medical University of Hannover, Hannover, Germany (C.H.); Department of Neuropathology, Heinrich-Heine-University, Düsseldorf, Germany (J.F., G.R.); German Consortium for Translational Cancer Research (DKTK), Düsseldorf, Germany (M.P., G.R.); Institute for Neuropathology, Saarland University, 66421 Saarbrücken, Germany (W.F.); Institute for Neuropathology, University of Essen Medical School, Essen, Germany (K.K.); Institute for Neuropathology, University of Tübingen, Tübingen, Germany (R.M.); Department of Neuropathology, University of Bonn Medical Center, Bonn, Germany (T.P.); Department of Neurology, University Hospital Zurich, Zürich, Switzerland (M.W.).

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http://dx.doi.org/10.1093/neuonc/nou138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232086PMC
December 2014

Prediction of recurrence of non muscle-invasive bladder cancer by means of a protein signature identified by antibody microarray analyses.

Proteomics 2014 Jun 29;14(11):1333-42. Epub 2014 Apr 29.

Division of Functional Genome Analysis, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/pmic.201300320DOI Listing
June 2014

Plasma protein analysis of patients with different B-cell lymphomas using high-content antibody microarrays.

Proteomics Clin Appl 2013 Dec;7(11-12):802-12

Division of Functional Genome Analysis, Deutsches Krebsforschungszentrum, Heidelberg, Germany.

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http://dx.doi.org/10.1002/prca.201300048DOI Listing
December 2013

Targeted resequencing for analysis of clonal composition of recurrent gene mutations in chronic lymphocytic leukaemia.

Br J Haematol 2013 Nov 27;163(4):496-500. Epub 2013 Aug 27.

Department of Translational Oncology, National Centre for Tumour Diseases (NCT) and German Cancer Research Centre (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1111/bjh.12539DOI Listing
November 2013

Next-generation sequencing of cancer consensus genes in lymphoma.

Leuk Lymphoma 2013 Aug 14;54(8):1831-5. Epub 2013 Jun 14.

Department of Translational Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.3109/10428194.2013.796053DOI Listing
August 2013

Prognostic value of tumor progression-related gene expression in colorectal cancer patients.

J Cancer Res Clin Oncol 2012 Oct 22;138(10):1631-40. Epub 2012 May 22.

Chemotherapy and Toxicology Unit, German Cancer Research Center, Im Neuenheimer Feld 581, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00432-012-1238-7DOI Listing
October 2012

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

Cancer Cell 2012 Oct;22(4):425-37

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) Heidelberg, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ccr.2012.08.024DOI Listing
October 2012

Evaluation of incidence rates in pre-clinical studies using a Williams-type procedure.

Int J Biostat 2010 ;6(1):Article 15

Leibniz University Hannover, Germany.

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July 2012

Robust biclustering by sparse singular value decomposition incorporating stability selection.

Bioinformatics 2011 Aug 2;27(15):2089-97. Epub 2011 Jun 2.

Division of Biostatistics, DKFZ, 69120 Heidelberg, Germany.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btr322DOI Listing
August 2011

Molecular characterization of AML with ins(21;8)(q22;q22q22) reveals similarity to t(8;21) AML.

Genes Chromosomes Cancer 2011 Jan;50(1):51-8

Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1002/gcc.20830DOI Listing
January 2011

Assessment and optimisation of normalisation methods for dual-colour antibody microarrays.

BMC Bioinformatics 2010 Nov 12;11:556. Epub 2010 Nov 12.

Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany.

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http://dx.doi.org/10.1186/1471-2105-11-556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098099PMC
November 2010

SEURAT: visual analytics for the integrated analysis of microarray data.

BMC Med Genomics 2010 Jun 3;3:21. Epub 2010 Jun 3.

Department of Computer Oriented Statistics and Data Analysis, University of Augsburg, Universitätsstr, 14, 86159 Augsburg, Germany.

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http://bmcmedgenomics.biomedcentral.com/articles/10.1186/175
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http://dx.doi.org/10.1186/1755-8794-3-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2893446PMC
June 2010

Poly-k-trend tests for survival adjusted analysis of tumor rates formulated as approximate multiple contrast test.

J Biopharm Stat 2008 ;18(5):934-48

Leibniz University Hannover, Institute of Biostatistics, Hannover, Germany.

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http://dx.doi.org/10.1080/10543400802294285DOI Listing
November 2008

Approximate simultaneous confidence intervals for multiple contrasts of binomial proportions.

Biom J 2008 Oct;50(5):782-92

Institut für Biostatistik, Leibniz Universität Hannover, Herrenhäuser Str. 2, D-30419 Hannover, Germany.

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http://dx.doi.org/10.1002/bimj.200710465DOI Listing
October 2008